CN113180889A - Mitral valve replacement device and use method thereof - Google Patents
Mitral valve replacement device and use method thereof Download PDFInfo
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- CN113180889A CN113180889A CN202110323285.2A CN202110323285A CN113180889A CN 113180889 A CN113180889 A CN 113180889A CN 202110323285 A CN202110323285 A CN 202110323285A CN 113180889 A CN113180889 A CN 113180889A
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- leaflet
- replacement device
- native
- mitral valve
- valve
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2418—Scaffolds therefor, e.g. support stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2463—Implants forming part of the valve leaflets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
- A61F2/2466—Delivery devices therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2478—Passive devices for improving the function of the heart muscle, i.e. devices for reshaping the external surface of the heart, e.g. bags, strips or bands
- A61F2/2487—Devices within the heart chamber, e.g. splints
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0008—Fixation appliances for connecting prostheses to the body
- A61F2220/0016—Fixation appliances for connecting prostheses to the body with sharp anchoring protrusions, e.g. barbs, pins, spikes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
- A61F2230/0028—Shapes in the form of latin or greek characters
- A61F2230/0034—D-shaped
Landscapes
- Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Prostheses (AREA)
Abstract
The invention belongs to the technical field of medical instruments, and particularly relates to a mitral valve replacement device and a using method thereof, wherein the related device comprises a bracket for supporting artificial valve leaflets and an anchor for anchoring the artificial valve leaflets to native valve leaflets, the bracket is connected with a suture film through a suture line, and the bracket is of a D-shaped structure and is attached to the native valve; the artificial valve leaflet is fixedly connected with the bracket, and the anchoring piece is used for jointing the artificial valve leaflet with the native valve leaflet; according to the invention, the artificial valve leaflet device with the support is conveyed to the native valve position through the conveying device, so that the regurgitation of the valve caused by incomplete closure and calcification is effectively avoided; can also be used for replacing native valves, has the effect of reducing the volume of the ventricles, improves the cardiac function and has important clinical significance.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a mitral valve replacement device and a using method thereof.
Background
As percutaneous aortic valve replacement techniques mature and exhibit good prognosis, transcatheter mitral valve replacement becomes an important research and development direction for the treatment of mitral regurgitation, especially for severe regurgitation patients at high risk of surgery. Currently, various TMVR valves have entered clinical trials and achieved good preliminary follow-up results. Nevertheless, there is still a great innovation in various aspects such as the improvement of the valve.
For example, patent document No. cn202011228753.x discloses a percutaneous transcatheter mitral valve replacement system comprising a valve frame support, a prosthetic leaflet, and a ventricular septum anchor; a valve frame supporting body is arranged between the atrium and the ventricle, and is provided with a hollow cavity with two open ends; the inner wall of the cavity of the valve frame support body is provided with an artificial valve leaf; an interventricular septum anchor is arranged between the valve frame supporting body and the interventricular septum. However, this system does not address the problem of regurgitation due to valve insufficiency and calcification. For this reason, it is necessary to improve it to overcome the complement in practical use.
Disclosure of Invention
Based on the above-mentioned shortcomings and drawbacks of the prior art, it is an object of the present invention to at least address one or more of the above-mentioned problems of the prior art, in other words, to provide a mitral valve replacement device and a method of using the same that meets one or more of the above-mentioned needs.
In order to achieve the purpose, the invention adopts the following technical scheme:
a mitral valve replacement device comprises a bracket for supporting artificial valve leaflets and an anchor for anchoring the artificial valve leaflets to native valve leaflets, wherein the bracket is connected with a suture film through a suture line, and is in a D-shaped structure and is attached to the native valve; the artificial valve leaflet is fixedly connected with the bracket, and the anchoring piece is used for jointing the artificial valve leaflet with the native valve leaflet.
Preferably, the outer side of the stent is fixedly provided with barbs so that the stent is attached to the native valve annulus; the stent is in a net rhombus shape and is formed by one or more of cutting, welding or weaving.
Preferably, the anchor comprises a fixing portion and an anchoring portion, the fixing portion is fixedly connected with the artificial valve leaflet, and the anchoring portion is fixedly connected with the native valve leaflet.
Preferably, the anchoring part is in a barb shape; the anchor is any one or more of a high polymer material and a metal material.
Preferably, one end of the artificial valve leaflet is sewed at the bottom of the support through a suture, and the other end of the artificial valve leaflet is anchored at the tail end of the native valve leaflet through an anchor.
Preferably, the material of the artificial valve leaflet is one or more of bovine pericardium, porcine pericardium or porcine heart valve; the thickness of the artificial valve leaflet is 0.05-0.1 mm.
Preferably, the sewing film is one or more of PET, polyurethane and PTFE.
Preferably, the suture films are sutured on the inner side and the outer side of the support through sutures.
Preferably, the suture line is one or more of a polymer material, PET, PTFE, e-PTFE, biological tissue and a tissue engineering material; the diameter of the suture is 0.01-0.5 mm.
The invention also provides a use method of the mitral valve replacement device, which comprises the following steps:
s1, placing the mitral valve replacement device into a delivery pipe, and delivering the mitral valve replacement device to the native valve leaflet position through the delivery pipe;
s2, releasing the mitral valve replacement device onto the native leaflets via the delivery device;
s3, anchoring the artificial valve leaflet on the native valve leaflet through the anchoring piece;
and S4, evacuating the conveying device.
Compared with the prior art, the invention has the beneficial effects that:
the mitral valve replacement device is conveyed to the native valve position through the conveying device and is firmly positioned through the anchoring piece, so that the mitral valve replacement device is used for valve insufficiency and regurgitation caused by calcification; can also be used for replacing native valves, has the effect of reducing the volume of the ventricles, improves the cardiac function and has important clinical significance.
The stent of the mitral valve replacement device is of a D-shaped structure, is matched with the opening shape of the mitral valve, has smooth outer surface and cannot cause tissue damage such as cardiac muscle, valve leaflet and the like.
Drawings
Fig. 1 is a schematic view of the overall structure of a mitral valve replacement device according to a first embodiment of the present invention;
fig. 2 is a schematic view of a stent structure of a mitral valve replacement device according to a first embodiment of the present invention;
FIG. 3 is a top view of a mitral valve replacement device in accordance with a first embodiment of the present invention;
FIG. 4 is a schematic view of an anchor of a mitral valve replacement device according to a first embodiment of the present invention;
FIG. 5 is a schematic illustration of a mitral valve replacement device according to a first embodiment of the present invention;
FIG. 6 is a schematic view of a mitral valve replacement device according to a first embodiment of the present invention from another perspective;
in the figure: 1 stent, 2 barbs, 3 artificial valve leaflets, 4 suture films, 5 anchors, 51 fixation parts, 52 anchor parts.
Detailed Description
In order to more clearly illustrate the embodiments of the present invention, the following description will explain the embodiments of the present invention with reference to the accompanying drawings. It is obvious that the drawings in the following description are only some examples of the invention, and that for a person skilled in the art, other drawings and embodiments can be derived from them without inventive effort.
The first embodiment is as follows:
as shown in fig. 1 to 6, the present embodiment provides a mitral valve replacement device, comprising a stent 1 for supporting a prosthetic leaflet 3 and an anchor 5 for anchoring the prosthetic leaflet 3 to a native leaflet, wherein the stent 1 is connected with a suture film 4 by a suture, and the stent 1 has a "D" shape and is attached to the native valve; the artificial valve leaflet 3 is fixedly connected with the bracket 1, and the anchoring piece 5 is used for jointing the artificial valve leaflet 3 with the native valve leaflet.
Specifically, the anchor 5 includes a fixing portion 51 and an anchoring portion 52, the fixing portion 51 is fixedly connected with the artificial valve leaflet 3, the anchoring portion 52 is in a barb shape, the anchoring portion 52 is fixedly connected with the native valve leaflet, the anchor 5 is made of any one or more of a polymer material and a metal material, and the anchor can be selected according to actual requirements in a specific using process.
In this embodiment, the anchoring member has two barb-shaped anchoring portions, the two anchoring portions are arranged relatively, and the directions of the barbs are respectively folded towards one side of the fixing portion, the anchoring portions can also be uniformly arranged along the circumferential direction of the fixing portion, the number of the anchoring portions is not limited to two in this embodiment, and the specific number can be set according to actual requirements; when the anchoring piece fixes the artificial valve leaflet and the native valve leaflet, the artificial valve leaflet and the native valve leaflet are anchored more firmly, the artificial valve leaflet can be prevented from slipping off when being attached to the native valve leaflet, and the artificial valve leaflet is not easy to shift.
The outer side of the bracket 1 is fixedly provided with a plurality of barbs 2, the directions of all the barbs 2 are kept consistent, and the barbs 2 can penetrate into a target position to further stabilize the device while forming a clamping surface, so that the bracket 1 is attached to the native valve ring; the stent 1 is in a net rhombus shape, is formed in one or more modes of cutting, welding or weaving, is more attached to a native valve, improves the stability of the structure, and can be selected according to actual requirements in a specific forming mode.
The stent 1 in the embodiment is of a D-shaped structure, is adaptive to the opening shape of the mitral valve, has smooth outer surface and cannot cause tissue damage such as cardiac muscle, valve leaflets and the like.
The artificial valve leaflet 3 is made of one or a combination of more of bovine pericardium, porcine pericardium or porcine heart valve, can also be made of non-biological flexible material, can float and swing along blood flow, can avoid calcification and can be used for a long time; the thickness of the artificial valve leaflet 3 is 0.05-0.1 mm, and the artificial valve leaflet can be selected preferentially according to the damage of the native valve leaflet of a patient and the pressure environment of the heart in practical application.
The material of the sewing membrane 4 is one or more of PET, polyurethane, PTFE, can specifically select according to the actual demand, sews up membrane 4 through the stylolite and sews up in the inside and outside both sides of support 1 to improve the structural strength of support 1.
One end of the artificial valve leaflet 3 is sewed at the bottom of the support 1 through a suture, and the other end of the artificial valve leaflet 3 is anchored at the tail end of the native valve leaflet through an anchoring piece 5.
The suture line is made of one or more of high polymer materials, PET, PTFE, e-PTFE, biological tissues and tissue engineering, can be selected according to actual requirements in a specific using process, and has the diameter of 0.01-0.5 mm.
In this embodiment, the anchoring elements have a shape that conforms to the native leaflets to attach to the native leaflets, avoiding twisting of the stent, thereby preventing tearing damage to the tissue when the anchoring elements are in an anchoring relationship with the tissue. In addition, the release path anchored on the inner wall of the cardiac apex is a straight path, and the release mode is relatively easier.
Correspondingly, the invention also provides a use method of the mitral valve replacement device, which comprises the following steps:
s1, placing the mitral valve replacement device into a delivery pipe, and delivering the mitral valve replacement device to the native valve leaflet position through the delivery pipe;
s2, releasing the mitral valve replacement device onto the native leaflets via the delivery device;
s3, anchoring the artificial valve leaflet on the native valve leaflet through the anchoring piece;
s4, the delivery device is withdrawn to effect delivery of the mitral valve replacement device into the atrium.
Compared with the prior art, the invention has the following beneficial effects:
according to the invention, the mitral valve device with the support is conveyed to the native valve position through the conveying device and is firmly positioned through the anchoring piece, so that regurgitation of the valve caused by incomplete closure and calcification is effectively avoided; meanwhile, the heart valve can be used for replacing a native valve, has the effect of reducing the volume of a ventricle, improves the cardiac function and has important clinical significance.
Example two:
the present embodiment provides a mitral valve replacement device, which is different from the first embodiment in that:
compared with the first embodiment, the anchor can be a threaded anchor or a gasket anchor, and the anchoring and the release after implantation of the threaded anchor are more convenient without limiting the form of a barb-shaped anchor; the gasket anchoring piece can be arranged outside the apex of the heart, can adjust the length of the pull rope and enhances the anchoring effect.
Other specific structures and methods of use can be seen with reference to example one.
The foregoing has outlined rather broadly the preferred embodiments and principles of the present invention and it will be appreciated that those skilled in the art may devise variations of the present invention that are within the spirit and scope of the appended claims.
Claims (10)
1. A mitral valve replacement device is characterized by comprising a bracket for supporting a prosthetic valve leaflet and an anchor for anchoring the prosthetic valve leaflet to a native valve leaflet, wherein the bracket is connected with a suture film through a suture line, and is of a D-shaped structure and is attached to the native valve; the artificial valve leaflet is fixedly connected with the bracket, and the anchoring piece is used for jointing the artificial valve leaflet with the native valve leaflet.
2. The mitral valve replacement device of claim 1, wherein barbs are fixedly provided on the outside of the stent to attach the stent to the native annulus; the stent is in a net rhombus shape and is formed by one or more of cutting, welding or weaving.
3. The mitral valve replacement device of claim 1, wherein the anchor comprises a fixation portion and an anchor portion, the fixation portion being fixedly connected to the prosthetic leaflet and the anchor portion being fixedly connected to the native leaflet.
4. A mitral valve replacement device according to claim 3, wherein the anchoring portion is barb-shaped; the anchor is any one or more of a high polymer material and a metal material.
5. The mitral valve replacement device of claim 1, wherein one end of the prosthetic leaflet is sutured to the base of the holder with a suture, and the other end of the prosthetic leaflet is anchored to the trailing end of the native leaflet with an anchor.
6. The mitral valve replacement device of claim 1, wherein the prosthetic leaflet is made of one or more of bovine pericardium, porcine pericardium, or porcine heart valve; the thickness of the artificial valve leaflet is 0.05-0.1 mm.
7. The mitral valve replacement device of claim 1, wherein the sewing membrane is one or more of PET, polyurethane, PTFE.
8. The mitral valve replacement device of claim 1, wherein the suture membranes are sutured to the stent on both the inner and outer sides with sutures.
9. The mitral valve replacement device of claim 1, wherein the suture is one or more of a polymer material, PET, PTFE, e-PTFE, biological tissue, tissue engineering material; the diameter of the suture is 0.01-0.5 mm.
10. A method of using a mitral valve replacement device according to any one of claims 1 to 9, comprising the steps of:
s1, placing the mitral valve replacement device into a delivery pipe, and delivering the mitral valve replacement device to the native valve leaflet position through the delivery pipe;
s2, releasing the mitral valve replacement device onto the native leaflets via the delivery device;
s3, anchoring the artificial valve leaflet on the native valve leaflet through the anchoring piece;
and S4, evacuating the conveying device.
Priority Applications (1)
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CN202110323285.2A CN113180889A (en) | 2021-03-26 | 2021-03-26 | Mitral valve replacement device and use method thereof |
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CN202110323285.2A CN113180889A (en) | 2021-03-26 | 2021-03-26 | Mitral valve replacement device and use method thereof |
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CN202110323285.2A Pending CN113180889A (en) | 2021-03-26 | 2021-03-26 | Mitral valve replacement device and use method thereof |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117982261A (en) * | 2022-10-27 | 2024-05-07 | 合源医疗器械(上海)有限公司 | Medical Devices |
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US20160030176A1 (en) * | 2014-08-04 | 2016-02-04 | Medizinische Universität Wien | Implant and method for improving coaptation of an atrioventricular valve |
CN105682611A (en) * | 2013-10-28 | 2016-06-15 | 坦迪尼控股股份有限公司 | Prosthetic heart valve and systems and methods for delivering the same |
US20170095332A1 (en) * | 2015-10-06 | 2017-04-06 | W. L. Gore & Associates, Inc. | Leaflet support devices and methods of making and using the same |
WO2018142217A2 (en) * | 2017-02-06 | 2018-08-09 | Hazu Gmbh | Methods and systems for assisting or repairing prosthetic cardiac valves |
CN109009569A (en) * | 2018-09-07 | 2018-12-18 | 谭雄进 | A kind of artificial mitral valve intervention displacement apparatus and its interventional method |
US20190201191A1 (en) * | 2017-08-31 | 2019-07-04 | Half Moon Medical, Inc. | Prosthetic leaflet device |
CN111067666A (en) * | 2019-12-17 | 2020-04-28 | 宁波健世生物科技有限公司 | Transcatheter valve replacement system |
CN111467082A (en) * | 2020-04-02 | 2020-07-31 | 科凯(南通)生命科学有限公司 | Valve ring contracts device |
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2021
- 2021-03-26 CN CN202110323285.2A patent/CN113180889A/en active Pending
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CN105682611A (en) * | 2013-10-28 | 2016-06-15 | 坦迪尼控股股份有限公司 | Prosthetic heart valve and systems and methods for delivering the same |
US20160030176A1 (en) * | 2014-08-04 | 2016-02-04 | Medizinische Universität Wien | Implant and method for improving coaptation of an atrioventricular valve |
US20170095332A1 (en) * | 2015-10-06 | 2017-04-06 | W. L. Gore & Associates, Inc. | Leaflet support devices and methods of making and using the same |
WO2018142217A2 (en) * | 2017-02-06 | 2018-08-09 | Hazu Gmbh | Methods and systems for assisting or repairing prosthetic cardiac valves |
US20190201191A1 (en) * | 2017-08-31 | 2019-07-04 | Half Moon Medical, Inc. | Prosthetic leaflet device |
CN109009569A (en) * | 2018-09-07 | 2018-12-18 | 谭雄进 | A kind of artificial mitral valve intervention displacement apparatus and its interventional method |
CN111067666A (en) * | 2019-12-17 | 2020-04-28 | 宁波健世生物科技有限公司 | Transcatheter valve replacement system |
CN111467082A (en) * | 2020-04-02 | 2020-07-31 | 科凯(南通)生命科学有限公司 | Valve ring contracts device |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117982261A (en) * | 2022-10-27 | 2024-05-07 | 合源医疗器械(上海)有限公司 | Medical Devices |
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Application publication date: 20210730 |