CN113145288B - A new type of microbead screening device and method - Google Patents
A new type of microbead screening device and method Download PDFInfo
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- 239000011325 microbead Substances 0.000 title claims abstract description 124
- 238000012216 screening Methods 0.000 title claims abstract description 31
- 238000000034 method Methods 0.000 title claims description 26
- 238000005192 partition Methods 0.000 claims abstract description 75
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 51
- 239000007788 liquid Substances 0.000 claims abstract description 40
- 238000004062 sedimentation Methods 0.000 claims abstract description 7
- 230000005484 gravity Effects 0.000 claims description 9
- 238000003756 stirring Methods 0.000 claims description 7
- 230000001133 acceleration Effects 0.000 claims description 6
- 239000011324 bead Substances 0.000 description 4
- 238000006073 displacement reaction Methods 0.000 description 4
- 239000002245 particle Substances 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 241000283070 Equus zebra Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
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Abstract
Description
技术领域Technical field
本发明应用微珠生产领域,具体涉及一种新型微珠装置及方法。The invention is applied in the field of microbead production, and specifically relates to a new type of microbead device and method.
背景技术Background technique
玻璃微珠是近年来发展迅速、用途广泛、性能特殊的一种新型材料,应用于航空航天机械的除锈、城市交通道路的斑马线、禁停线、双黄线的夜间反光和交通标志牌的夜间反光装置中。目前,在反光微玻璃珠在制造过程中,为了遴选等直径的颗粒,往往采用颗粒筛进行筛选,但是颗粒筛筛选速度慢,效率低且不能适应于大规模的生产。Glass beads are a new type of material that has developed rapidly in recent years, has a wide range of uses, and has special properties. It is used in rust removal of aerospace machinery, zebra crossings, no-stop lines, double yellow lines on urban traffic roads, and night reflections on traffic signs. Reflective device at night. At present, in the manufacturing process of reflective microglass beads, in order to select particles of equal diameters, particle sieves are often used for screening. However, the particle sieve screening speed is slow, the efficiency is low, and it cannot be adapted to large-scale production.
发明内容Contents of the invention
本发明的目的在于提供一种新型微珠筛选装置及方法,提高了微珠筛选的效率。The purpose of the present invention is to provide a new microbead screening device and method, which improves the efficiency of microbead screening.
为解决上述技术问题,本发明提供了一种技术方案:一种新型微珠筛选装置,包括:In order to solve the above technical problems, the present invention provides a technical solution: a new microbead screening device, including:
具有一定高度的水槽,水槽内盛放有具有一定水平流速V的液体;A water tank with a certain height, which contains liquid with a certain horizontal flow rate V;
容器,设置于所述水槽上方,用于盛放待筛选的微珠,所述微珠包括当量直径分别为dp1、dp2、dp3……dp(n-1)的微珠;容器下方设有卡槽,卡槽中设有可抽离的卡板,当卡板被抽离时,容器中的微珠落入所述水槽内,进行沉降筛选;A container is arranged above the water tank for holding microbeads to be screened. The microbeads include microbeads with equivalent diameters of d p1 , d p2 , d p3 ...d p(n-1) respectively; container There is a card slot below, and a removable card plate is provided in the card slot. When the card plate is pulled away, the microbeads in the container fall into the water tank for sedimentation and screening;
采集通道,设置于水槽底部,用于筛选和采集微珠,包括按照所述液体的流动方向依次设置的第一至第n隔板;其中第一隔板和第二隔板之间形成第一采集通道,第二隔板和第三隔板之间形成第二采集通道,第三隔板和第四隔板之间形成第三采集通道……第n-1隔板和第n隔板之间形成第n-1采集通道;其中第一采集通道、第二采集通道、第三采集通道……第n-1采集通道分别用于采集当量直径为dp1、dp2、dp3……dp(n-1)的微珠;A collection channel is provided at the bottom of the water tank for screening and collecting microbeads, and includes first to nth partitions arranged in sequence according to the flow direction of the liquid; wherein a first partition is formed between the first partition and the second partition. Collection channel, the second collection channel is formed between the second partition and the third partition, and the third collection channel is formed between the third partition and the fourth partition... Between the n-1th partition and the nth partition The n-1th collection channel is formed between them; the first collection channel, the second collection channel, the third collection channel... the n-1th collection channel are used to collect the equivalent diameters of d p1 , d p2 , d p3 ...d respectively. p(n-1) microbeads;
各隔板的高度和位置按以下公式确定:The height and position of each partition are determined according to the following formula:
第一隔板上端距离卡板的垂直距离为Sn;The vertical distance between the upper end of the first partition and the clamping plate is S n ;
第二隔板上端距离卡板的垂直距离为Sn;The vertical distance between the upper end of the second partition and the clamping plate is S n ;
第三隔板上端距离卡板的垂直距离为Sn-h2;The vertical distance between the upper end of the third partition and the clamping plate is S n -h 2 ;
第四隔板上端距离卡板的垂直距离为Sn-h3;The vertical distance between the upper end of the fourth partition and the clamping plate is S n -h 3 ;
………
第n隔板上端距离卡板的垂直距离为Sn-hn-1;The vertical distance between the upper end of the n-th partition and the clamping plate is Sn -h n-1 ;
其中 in
第n隔板、第n-1隔板,第n-2隔板……第二隔板与容器右侧的水平距离分别为Wn-1、Wn-2、Wn-3……W1;The horizontal distances between the n-th partition, the n-1 partition, the n-2 partition...the second partition and the right side of the container are W n-1 , W n-2 , W n-3 ...W respectively. 1 ;
其中 式中ρp为所述微珠的密度,ρ为所述液体的密度,g为重力加速度,μ为动力粘度。in In the formula, ρ p is the density of the microbeads, ρ is the density of the liquid, g is the acceleration of gravity, and μ is the dynamic viscosity.
按上述方案,所述水槽侧方连通有搅拌水槽,用于产生所述一定水平流速V的液体。According to the above solution, a stirring water tank is connected to the side of the water tank for generating liquid with a certain horizontal flow rate V.
按上述方案,所述的n=4。According to the above scheme, the n=4.
一种微珠筛选方法,包括以下步骤:A microbead screening method includes the following steps:
S1、将待筛选的微珠放入容器内,当水槽中的液体的水平流速为匀速V时,抽离卡板,微珠落入水槽中;S1. Put the microbeads to be screened into the container. When the horizontal flow rate of the liquid in the water tank is constant speed V, pull out the card and the microbeads fall into the water tank;
S2、不同当量直径的微珠在水槽中水平流速为V的液体的影响下进行沉降,其中微珠根据当量直径的不同,由大到小分别落入第一至第n-1采集通道,从而完成对微珠的筛选。S2. Microbeads with different equivalent diameters settle under the influence of the liquid with a horizontal flow rate of V in the water tank. The microbeads fall into the first to n-1 collection channels from large to small according to the different equivalent diameters, so that Complete the screening of microbeads.
按上述方案,所述的S1中,根据待筛选的微珠直径、密度,以及容器中液体的密度、预设的水平流速V,设计水槽中各部分的尺寸。According to the above scheme, in S1, the size of each part in the water tank is designed according to the diameter and density of the beads to be screened, the density of the liquid in the container, and the preset horizontal flow rate V.
按上述方案,所述的S1中,先在水槽中加入液体,启动水槽侧方连通的搅拌水槽,待液体的水平流速达到匀速V时,再将待筛选的微珠放入水槽内。According to the above scheme, in S1, liquid is first added to the water tank, and the stirring water tank connected to the side of the water tank is started. When the horizontal flow rate of the liquid reaches a uniform speed V, the microbeads to be screened are then placed into the water tank.
本发明的有益效果为:通过设置容器可实现单次对大量的微珠进行筛选,通过设置水槽以及采集通道,利用不同当量直径微珠在流动液体中水平移动速度和沉降速度的不同,可实现对微珠的快速筛选;The beneficial effects of the present invention are: by setting up a container, a large number of microbeads can be screened at a time; by setting up a water tank and a collection channel, and utilizing the differences in the horizontal movement speed and settling speed of microbeads with different equivalent diameters in the flowing liquid, it can be achieved Rapid screening of microbeads;
进一步地,本装置可通过调整各隔板距离容器右侧的距离,以此调整采集通道的位置以及宽度,从而调整采集通道所收集的微珠规格;Furthermore, this device can adjust the position and width of the collection channel by adjusting the distance between each partition and the right side of the container, thereby adjusting the specifications of the microbeads collected by the collection channel;
进一步地,本装置通过设置不同隔板的高度,可实现不同当量直径的微珠于同一时间落入采集通道,进一步提升了对微珠的筛选效率。Furthermore, by setting the height of different partitions, this device can realize that microbeads with different equivalent diameters fall into the collection channel at the same time, further improving the screening efficiency of microbeads.
附图说明Description of drawings
图1为本发明一实施例的结构示意图;Figure 1 is a schematic structural diagram of an embodiment of the present invention;
图中:1-水槽,2-容器,3-卡板,4-微珠,5-第一采集通道,6-第二采集通道,7-第三采集通道,8-第一隔板,9-第二隔板,10-第三隔板,11-第四隔板。In the picture: 1-sink, 2-container, 3-cardboard, 4-microbeads, 5-first collection channel, 6-second collection channel, 7-third collection channel, 8-first partition, 9 -Second partition, 10-Third partition, 11-Fourth partition.
具体实施方式Detailed ways
为使本公开实施例的目的、技术方案和优点更加清楚,下面将结合本公开实施例的附图,对本公开实施例的技术方案进行清楚、完整地描述。显然,所描述的实施例是本公开的一部分实施例,而不是全部的实施例。基于所描述的本公开的实施例,本领域普通技术人员在无需创造性劳动的前提下所获得的所有其他实施例,都属于本公开保护的范围。In order to make the purpose, technical solutions and advantages of the embodiments of the present disclosure more clear, the technical solutions of the embodiments of the present disclosure will be clearly and completely described below in conjunction with the drawings of the embodiments of the present disclosure. Obviously, the described embodiments are some, but not all, of the embodiments of the present disclosure. Based on the described embodiments of the present disclosure, all other embodiments obtained by those of ordinary skill in the art without creative efforts fall within the scope of protection of the present disclosure.
参见图1,一种新型微珠筛选装置,包括:Referring to Figure 1, a new type of microbead screening device includes:
具有一定高度的水槽1,水槽1内盛放有具有一定水平流速V的液体;The water tank 1 has a certain height, and the water tank 1 contains liquid with a certain horizontal flow rate V;
容器2,设置于水槽1上方,用于盛放待筛选的微珠4,微珠4包括当量直径分别为dp1、dp2、dp3……dp(n-1)的微珠4;容器2下方设有卡槽,卡槽中设有可抽离的卡板3,当卡板3被抽离时,容器2中的微珠4落入所述水槽1内,进行沉降筛选;Container 2 is set above the water tank 1 and is used to hold microbeads 4 to be screened. The microbeads 4 include microbeads 4 with equivalent diameters of d p1 , d p2 , d p3 ... d p (n-1) ; There is a card slot below the container 2, and a removable card plate 3 is provided in the card slot. When the card plate 3 is pulled away, the microbeads 4 in the container 2 fall into the water tank 1 for sedimentation and screening;
采集通道,设置于水槽1底部,用于筛选和采集微珠4,包括按照所述液体的流动方向依次设置的第一至第n隔板;其中第一隔板8和第二隔板9之间形成第一采集通道5,第二隔板9和第三隔板10之间形成第二采集通道6,第三隔板10和第四隔板11之间形成第三采集通道7……第n-1隔板和第n隔板之间形成第n-1采集通道;其中第一采集通道5、第二采集通道6、第三采集通道7……第n-1采集通道分别用于采集当量直径为dp1、dp2、dp3……dp(n-1)的微珠4;The collection channel is provided at the bottom of the water tank 1 for screening and collecting microbeads 4, and includes first to nth partitions arranged in sequence according to the flow direction of the liquid; where the first partition 8 and the second partition 9 The first collection channel 5 is formed between, the second collection channel 6 is formed between the second partition 9 and the third partition 10, the third collection channel 7 is formed between the third partition 10 and the fourth partition 11... The n-1th collection channel is formed between the n-1 partition and the n-th partition; the first collection channel 5, the second collection channel 6, the third collection channel 7... the n-1th collection channel are used for collection respectively. Microbeads 4 with equivalent diameters d p1 , d p2 , d p3 ...d p(n-1) ;
各隔板的高度和位置按以下公式确定:The height and position of each partition are determined according to the following formula:
第一隔板8上端距离卡板3的垂直距离为Sn;The vertical distance between the upper end of the first partition plate 8 and the clamping plate 3 is Sn ;
第二隔板9上端距离卡板3的垂直距离为Sn;The vertical distance between the upper end of the second partition plate 9 and the clamping plate 3 is Sn ;
第三隔板10上端距离卡板3的垂直距离为Sn-h2;The vertical distance between the upper end of the third partition 10 and the clamping plate 3 is Sn -h 2 ;
第四隔板11上端距离卡板3的垂直距离为Sn-h3;The vertical distance between the upper end of the fourth partition plate 11 and the clamping plate 3 is Sn -h 3 ;
………
第n隔板上端距离卡板3的垂直距离为Sn-hn-1;The vertical distance between the upper end of the n-th partition and the clamping plate 3 is Sn -h n-1 ;
其中通过设置不同的隔板高度,使得所有采集通道都具有最快的采集速度;in By setting different partition heights, all acquisition channels have the fastest acquisition speed;
第n隔板、第n-1隔板,第n-2隔板……第二隔板9与容器2右侧的水平距离分别为Wn-1、Wn-2、Wn-3……W1;The horizontal distances between the n-th partition, the n-1 partition, the n-2 partition...the second partition 9 and the right side of the container 2 are W n-1 , W n-2 , W n-3 ... respectively. …W 1 ;
其中 式中ρp为微珠4的密度,ρ为所述液体的密度,g为重力加速度,μ为动力粘度。in In the formula, ρ p is the density of microbeads 4, ρ is the density of the liquid, g is the acceleration of gravity, and μ is the dynamic viscosity.
进一步地,水槽1侧方连通有搅拌水槽,用于产生所述一定水平流速V的液体。Furthermore, a stirring water tank is connected to the side of the water tank 1 for generating liquid with a certain horizontal flow rate V.
进一步地,所述的n=4。Further, the n=4.
本实施例中,微珠4包括三种当量直径的规格,分别为dp1=1000μm,dp2=100μm,dp3=10μm;下面对微珠4的运动过程作详细分析:In this embodiment, microbeads 4 include three specifications of equivalent diameters, namely d p1 =1000 μm, d p2 =100 μm, and d p3 =10 μm; the movement process of microbeads 4 is analyzed in detail below:
微珠4沉降过程,其垂直方向运动分为加速运动过程与匀速运动过程;During the settling process of microbeads 4, their vertical motion is divided into accelerated motion process and uniform motion process;
a)微珠匀速运动过程分析a) Analysis of uniform motion process of microbeads
当微珠4进行匀速运动时,微珠4所受有重力(mg)、浮力和拖曳力设此时微珠4的运动速度为ut,于是有:When the microbead 4 moves at a constant speed, the microbead 4 is subjected to gravity (mg), buoyancy and drag force Assume that the movement speed of microbead 4 at this time is u t , then there is:
整理得到速度公式:Organize and get the speed formula:
其中dp为微珠4的直径,ξD为曳力系数,ρp为微珠4的密度,ρ为液体的密度;Where d p is the diameter of the microbead 4, ξ D is the drag coefficient, ρ p is the density of the microbead 4, and ρ is the density of the liquid;
根据流体力学可知:According to fluid mechanics, it can be known:
1、Rep≤2,为层流区,又称斯托克斯区,此时1. Re p ≤ 2, it is the laminar flow zone, also known as the Stokes zone. At this time
2、2≤Rep≤500,为过渡区,又称阿仑区,此时2. 2≤Re p ≤500, which is the transition zone, also known as the Allen zone. At this time
3、500<Rep<2×105,为湍流区,又称牛顿区,此时3. 500<Re p <2×10 5 is the turbulent zone, also known as the Newton zone. At this time
ξD≈0.44 (5) ξD≈0.44 (5)
4、Rep≥2×105时,ξD将突然下降,呈现不规则现象;4. When Re p ≥2×10 5 , ξ D will suddenly drop and show irregularities;
其中,Rep为雷诺数,Rep=dputρ/μ,曳力系数ξD为雷诺数的函数,μ为动力粘度(Pa·S),本实施例中仅对层流区进行分析。Among them, Re p is the Reynolds number, Re p =d p u t ρ/μ, the drag coefficient ξ D is a function of the Reynolds number, and μ is the dynamic viscosity (Pa·S). In this embodiment, only the laminar flow region is tested. analyze.
将式(3)中曳力系数ξD代入沉降速度ut的表达式中,得到:Substituting the drag coefficient ξ D in equation (3) into the expression of settlement velocity u t , we get:
沉降过程中,不同微珠4会相互干扰,其中微珠4有丝状、片状等不规则形状,在计算时应以当量直径代入,并通过下式进行修正:During the settling process, different microbeads 4 will interfere with each other. The microbeads 4 have irregular shapes such as filamentous and flaky shapes. When calculating, the equivalent diameter should be substituted and corrected by the following formula:
其中,i为微珠4与液体的体积比;α为形状影响因子,为i的函数,关系式如下表:Among them, i is the volume ratio of microbeads 4 to liquid; α is the shape influence factor, which is a function of i. The relationship formula is as follows:
表1沉降速度微珠形状影响因子Table 1 Factors affecting the shape of sedimentation velocity microbeads
b)微珠加速运动分析b) Analysis of accelerated movement of microbeads
微珠4在液体中做加速运动时,垂直方向上受到的力有浮力Fb、曳力FD、重力FB,于是有:When the microbead 4 accelerates in the liquid, the forces it receives in the vertical direction include buoyancy force F b , drag force F D , and gravity F B , so there is:
其中ρp为微珠4的密度,ρ为液体的密度;Where ρ p is the density of microbeads 4, and ρ is the density of liquid;
根据牛顿第二定律有:According to Newton's second law:
FB=Fb-FD=ma (11)F B =F b -F D =ma (11)
式中ξD为曳力系数,A为微珠4在流动方向上的投影面积,a为微珠4的加速度。In the formula, ξ D is the drag coefficient, A is the projected area of the microbead 4 in the flow direction, and a is the acceleration of the microbead 4.
建立微珠4运动方程如下:The motion equation of microbead 4 is established as follows:
S=A+Bt+Ct2+Dt3 (12)S=A+Bt+Ct 2 +Dt 3 (12)
S′=B+2Ct+3Dt2 (13)S′=B+2Ct+3Dt 2 (13)
S″=2C+6Dt (14)S″=2C+6Dt (14)
S″′=6D (15)S″′=6D (15)
式中,S为微珠4沉降的高度,A、B、C、D为式(12)一元三次方程的待定系数;t=0时,可得:In the formula, S is the height of the settlement of microbead 4, and A, B, C, and D are the undetermined coefficients of the cubic equation of equation (12); when t=0, we can get:
S=A+Bt+Ct2+Dt3=0 (16)S=A+Bt+Ct 2 +Dt 3 =0 (16)
可得A=0;It can be obtained that A=0;
微珠4开始运动时,其速度为0,即S′=0,所以有:When microbead 4 starts to move, its speed is 0, that is, S′=0, so there is:
S′=B+2Ct+3Dt2=0 (17)S′=B+2Ct+3Dt 2 =0 (17)
可得B=0;It can be obtained that B=0;
将A=0、B=0代入式(12)、式(13)、式(14)、式(15)中,得到:Substituting A=0 and B=0 into formula (12), formula (13), formula (14), and formula (15), we get:
S=Ct2+Dt3 (18)S=Ct 2 +Dt 3 (18)
S′=2Ct+3Dt2 (19)S′=2Ct+3Dt 2 (19)
由于微珠4刚开始运动时,其速度为0,所受的拖曳力也为0,微珠4此时所受力可表示为:Since when microbead 4 first starts moving, its speed is 0 and the drag force it experiences is also 0. The force on microbead 4 at this time can be expressed as:
其中a0为初始加速度,m为微珠4质量,于是可得:Among them, a 0 is the initial acceleration, m is the mass of microbead 4, so we can get:
由式(8)、式(9)、式(11)可得:From formula (8), formula (9), and formula (11), we can get:
S″=2C+6Dt=a0 (22)S″=2C+6Dt=a 0 (22)
将t=0代入式(23)得到:Substituting t=0 into equation (23) we get:
假设当t=T时,微珠4所受重力、浮力以及拖曳力达到平衡,根据式(6)有:Assume that when t=T, the gravity, buoyancy and drag force on the microbead 4 are balanced. According to equation (6):
因为此时微珠4垂直方向所受合力为0,即加速度也为0,S″=0,所以有:Because the resultant force in the vertical direction of microbead 4 is 0 at this time, that is, the acceleration is also 0, S″=0, so there is:
S″=2C+6DT=0 (26)S″=2C+6DT=0 (26)
将式(27)代入式(25)中有:Substitute equation (27) into equation (25):
将式(24)代入(28)的解有:The solution of substituting equation (24) into (28) is:
将式(29)、式(24)代入式(28)中,可得:Substituting formula (29) and formula (24) into formula (28), we can get:
其中T表示微珠4从开始运动到所受的重力、浮力、拖曳力达到平衡所需的时间;虽然式(30)无法直接得出T与微珠4与液体的比重有直接关系,但动力粘度μ与液体的比重有直接关系,μ=ρν,其中ν为运动粘度;Among them, T represents the time required for the microbead 4 to reach equilibrium from the beginning of its movement to the gravity, buoyancy, and drag force. Although Equation (30) cannot directly conclude that T is directly related to the specific gravity of the microbead 4 and the liquid, the dynamic force The viscosity μ is directly related to the specific gravity of the liquid, μ=ρν, where ν is the kinematic viscosity;
将式(30)、式(29)、式(24)代入式(18)得到微珠4所受的三个作用力达到平衡所需要的运动的高度距离:Substitute equation (30), equation (29), and equation (24) into equation (18) to obtain the height distance of movement required for the three forces on microbead 4 to reach equilibrium:
本实施例中,装置处于20℃环境下,微珠4与液体的动力粘度为1Pa·S,微珠4的当量直径分为10μm、100μm、1000μm,下面分别分析三种微珠4的沉降过程;In this example, the device is in an environment of 20°C, the dynamic viscosity of the microbeads 4 and the liquid is 1 Pa·S, and the equivalent diameters of the microbeads 4 are divided into 10 μm, 100 μm, and 1000 μm. The sedimentation processes of the three types of microbeads 4 are analyzed below. ;
通过式(30)可得到三种微珠4在加速运动过程中,受到的三个作用力达到平衡所需的运动时间和运动距离分别为:Through equation (30), it can be obtained that the movement time and movement distance required for the three forces received by the three types of microbeads 4 to reach equilibrium during the accelerated movement are:
微珠4当量直径为10μm:The equivalent diameter of microbeads is 10μm:
微珠4当量直径为100μm:The equivalent diameter of microbeads is 100μm:
微珠4当量直径为1000μm:The equivalent diameter of microbeads is 1000μm:
由此可以看出三种不同当量直径的微珠4的加速运动过程时间和距离都很小,可以忽略不计,下面分析微珠4在液体中做匀速运动的过程:It can be seen from this that the time and distance of the accelerated motion process of microbeads 4 of three different equivalent diameters are very small and can be ignored. The process of uniform motion of microbeads 4 in the liquid is analyzed below:
(a)当微珠4直径为10μm时:(a) When the diameter of microbead 4 is 10 μm:
微珠4在所受三个作用力达到平衡后做匀速运动,其初速度为:Microbead 4 moves at a uniform speed after the three forces it receives reach equilibrium. Its initial speed is:
沉降时间为:The settling time is:
(b)当微珠4直径为100μm时:(b) When the diameter of microbead 4 is 100 μm:
同理可得:In the same way, we can get:
(c)当微珠4直径为1000μm时:(c) When the diameter of microbead 4 is 1000 μm:
同理可得:In the same way, we can get:
其中,H1、H2、H3分别对应直径为10μm、100μm、1000μm的微珠4从开始做匀速运动到进入采集通道,其运动长度在垂直方向分量的距离,由于微珠4在垂直方向的运动分为加速运动过程和匀速运动过程,所以有:Among them, H 1 , H 2 , and H 3 respectively correspond to the distance in the vertical direction component of the movement length of microbeads 4 with diameters of 10 μm, 100 μm, and 1000 μm from the time when they start to move at a constant speed until they enter the collection channel. Since the microbeads 4 move in the vertical direction The motion is divided into accelerated motion process and uniform motion process, so there are:
Sn=S1+H1=S2+H2=S3+H3 (44)S n =S 1 +H 1 =S 2 +H 2 =S 3 +H 3 (44)
其中Sn为微珠4从离开容器3到进入采集通道的垂直位移距离,由于S1、S2、S3都很小,可以忽略不计,所以:Where S n is the vertical displacement distance of microbead 4 from leaving container 3 to entering the collection channel. Since S 1 , S 2 , and S 3 are all very small and can be ignored, so:
H1=H2=H3=Sn (45)H 1 =H 2 =H 3 =S n (45)
由此可得,当微珠4直径为1000μm时,其沉降所需时间t3最短,对应第一采集通道5,直径为100μm和10μm的微珠4分别对应第二采集通道6和第三采集通道7。It can be seen that when the diameter of the microbead 4 is 1000 μm, the time t 3 required for its settlement is the shortest, corresponding to the first collection channel 5, and the microbeads 4 with diameters of 100 μm and 10 μm correspond to the second collection channel 6 and the third collection respectively. Channel 7.
当微珠直径为1000μm时,落入第一采集通道5,其采集时间即沉降时间t3最短,若要使第二采集通道6的采集速度和第一采集通道5一样快,需要使第三隔板10相较于第二隔板9加高h2,则有:When the diameter of microbeads is 1000 μm and falls into the first collection channel 5, the collection time, that is, the settling time t3 is the shortest. If the collection speed of the second collection channel 6 is as fast as the first collection channel 5, the third collection channel 6 needs to be made as fast as the first collection channel 5. The partition 10 is higher than the second partition 9 by h 2 , then:
计算可得:Calculate:
同理,若要使第三采集通道7的采集速度和第一采集通道5一样快,需要使第四隔板11相较于第二隔板9加高h3,则有:In the same way, if you want to make the collection speed of the third collection channel 7 as fast as that of the first collection channel 5, you need to make the fourth partition 11 higher than the second partition 9 by h 3 , then:
计算可得:Calculate:
容器2的右侧与第四隔板11的水平距离为W3;W3为落入第三采集通道7的微珠4在沉降过程中进行的水平位移距离;W3的值为:The horizontal distance between the right side of the container 2 and the fourth partition 11 is W 3 ; W 3 is the horizontal displacement distance of the microbeads 4 falling into the third collection channel 7 during the settling process; the value of W 3 is:
容器2的右侧与第三隔板10的水平距离为W2;W2为落入第二采集通道6的微珠4在沉降过程中进行的水平位移距离;W2的值为:The horizontal distance between the right side of the container 2 and the third partition 10 is W 2 ; W 2 is the horizontal displacement distance of the microbeads 4 falling into the second collection channel 6 during the settling process; the value of W 2 is:
容器2的右侧与所述第二隔板9的水平距离为W1;W1为落入第一采集通道5的微珠4在沉降过程中进行的水平位移距离;W1的值为:The horizontal distance between the right side of the container 2 and the second partition 9 is W 1 ; W 1 is the horizontal displacement distance of the microbeads 4 falling into the first collection channel 5 during the settling process; the value of W 1 is:
一种新型微珠筛选方法,包括以下步骤:A new microbead screening method includes the following steps:
S1、将待筛选的微珠4放入容器2内,当水槽1中液体的水平流速为匀速V时,抽离卡板3,微珠4落入水槽1中;S1. Put the microbeads 4 to be screened into the container 2. When the horizontal flow rate of the liquid in the water tank 1 is a constant speed V, pull out the card 3 and the microbeads 4 fall into the water tank 1;
S2、不同当量直径的微珠4在水槽1中水平流速为V的液体的影响下进行沉降,其中微珠4根据当量直径的不同,由大到小分别落入第一至第n-1采集通道,从而完成对微珠4的筛选。S2. Microbeads 4 with different equivalent diameters settle under the influence of liquid with a horizontal flow rate V in the water tank 1. Microbeads 4 fall into the first to n-1 collections from large to small according to different equivalent diameters. channel, thereby completing the screening of microbeads 4.
进一步地,所述的S1中,根据待筛选的微珠4直径、密度,以及容器2中液体的密度、预设的水平流速V,设计水槽1中各部分的尺寸。Further, in S1, the size of each part in the water tank 1 is designed according to the diameter and density of the microbeads 4 to be screened, the density of the liquid in the container 2, and the preset horizontal flow rate V.
进一步地,所述的S1中,先在水槽1中加入液体,启动水槽1侧方连通的搅拌水槽,待液体的水平流速达到匀速V时,再将待筛选的微珠4放入水槽1内。Further, in the described S1, liquid is first added to the water tank 1, and the stirring water tank connected to the side of the water tank 1 is started. When the horizontal flow rate of the liquid reaches a uniform speed V, the microbeads 4 to be screened are then placed into the water tank 1. .
综上,本发明通过设置搅拌水槽使水槽内产生一定水平流速的液体,微珠在沉降过程中收到液体流速的影响落入预设位置的采集通道内,并且根据不同当量直径的微珠的沉降速度加高相应的采集通道的隔板,使得所有采集通道的采集速度都达到最大。In summary, the present invention generates a liquid with a certain horizontal flow rate in the water tank by setting up a stirring water tank. During the settling process, the microbeads are affected by the liquid flow rate and fall into the collection channel at the preset position. According to the different equivalent diameters of microbeads, The sedimentation velocity increases the partition wall of the corresponding collection channel, so that the collection speed of all collection channels reaches the maximum.
以上所述仅为本发明的实施例,并非因此限制本发明的专利范围,凡是利用本发明说明书及附图内容所作的等效结构或等效流程变换,或直接或间接运用在其它相关的技术领域,均同理包括在本发明的专利保护范围内。The above are only examples of the present invention, and do not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the description and drawings of the present invention, or directly or indirectly applied to other related technologies fields are equally included in the scope of patent protection of the present invention.
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