CN113101209A

CN113101209A - Liquid storage bag for mixing biological pharmaceutical liquid

Info

Publication number: CN113101209A
Application number: CN202110358545.XA
Authority: CN
Inventors: 秦孙星
Original assignee: Shanghai Lechunle New Material Co ltd; Shanghai Lepure Biotech Co ltd
Current assignee: Shanghai Lechunle New Material Co ltd; Shanghai Lepure Biotech Co ltd
Priority date: 2021-04-02
Filing date: 2021-04-02
Publication date: 2021-07-13
Anticipated expiration: 2041-04-02
Also published as: CN113101209B

Abstract

The invention belongs to the technical field of medical instruments, and particularly relates to a liquid storage bag for mixing biological pharmaceutical liquid, which comprises a connecting part for dividing the liquid storage bag into at least two mutually sealed liquid storage bags; the first liquid storage bag is provided with a one-way valve flowing from the outside to the first liquid storage bag; a sealing valve which is opened from outside to inside is arranged on the second liquid storage bag; a connecting device is connected between the first liquid storage bag and the second liquid storage bag; one end of the connecting device is fixedly connected to the first liquid storage bag, the other end of the connecting device is connected with the second liquid storage bag in a buckling mode, and the first liquid storage bag is communicated with the second liquid storage bag through the connecting device; the closing valve comprises a closing plate and a closing valve shell; a first accommodating cavity is arranged in the closed valve shell; the closing plate is positioned in the first accommodating cavity, and when the closing valve is closed, the upper surface of the closing plate is attached to the inner wall of the upper part of the first accommodating cavity; when the connecting device is buckled with the closing valve, the closing plate opens the closing valve under the action of the connecting device. The problem of the insufficient solder wire difficult to strut has been solved effectively.

Description

Liquid storage bag for mixing biological pharmaceutical liquid

Technical Field

The invention relates to the technical field of medical instruments, in particular to a liquid storage bag for mixing biological pharmaceutical liquid.

Background

Infusion is a dose of injection infused into a human body by intravenous drip, and the injection is usually packaged in a glass or plastic infusion bottle or infusion bag. The vertical polypropylene liquid storage bag is mainly made of polypropylene and polyethylene, is one of the safest infusion packaging materials at present, and is widely used clinically at present. When a patient is transfused, a certain dosage of therapeutic solution, such as glucose, sodium bicarbonate and potassium chloride solution which is clinically used for alkalinization and diuresis, is often required to be added into an infusion bottle or an infusion bag, and the therapeutic solution is formed by mixing more than two kinds of medicinal liquid, namely 5 percent of glucose, sodium bicarbonate and potassium chloride solution; the common method for infusing glucose sodium bicarbonate potassium chloride solution to a patient is that the solution is prepared on site before infusion, and the large-batch solution preparation on site wastes time and labor; in addition, there is a risk of scratching by the sodium bicarbonate ampoule when the medical personnel open the sodium bicarbonate bottle. Consequently, most medicine all is partial shipment with the stock solution bag at present, the joint seam with multiple liquid medicine through the rosin joint separates multiple liquid medicine, in the time of the use, the joint seam through the extrusion with the rosin joint struts, mix multiple liquid medicine, however, this kind of present packaging mode, when mixing, need use very big strength just can strut the joint seam of rosin joint, because present a lot of operators all are the less women's nurse of strength, lead to work efficiency low, when the urgent need is used medicine, there is the potential safety hazard even still to patient's first aid.

Disclosure of Invention

1. Technical problem to be solved

The invention aims to provide a liquid storage bag for mixing biological pharmaceutical liquid, aiming at the potential safety hazard caused by physical limitation when a plurality of liquid medicines are mixed by spreading a rosin joint through a mode that the liquid storage bag encapsulates the plurality of liquid medicines through the rosin joint in the prior art.

2. Technical scheme

In order to solve the above problems, the present invention adopts the following technical solutions.

A reservoir bag for mixing a biopharmaceutical liquid, comprising a connecting portion (1) dividing the reservoir bag into at least two mutually sealed reservoirs;

the separated liquid storage bags are respectively a first liquid storage bag (2) and a second liquid storage bag (3);

the first liquid storage bag (2) is provided with a one-way valve (21) flowing to the first liquid storage bag (2) from the outside;

a sealing valve (31) which is opened from outside to inside is arranged on the second liquid storage bag (3) so that the gas in the second liquid storage chamber (3) flows out;

a connecting device (4) is connected between the first liquid storage bag (2) and the second liquid storage bag (3);

one end of the connecting device (4) is fixedly connected to the first liquid storage bag (2), the other end of the connecting device (4) is connected with the second liquid storage bag (3) in a buckling mode, and the first liquid storage bag (2) is communicated with the second liquid storage bag (3) through the connecting device (4);

the closing valve (31) comprises a closing plate (311) and a closing valve housing (312);

a first accommodating cavity (312a) is arranged in the closed valve shell (312);

the closing plate (311) is positioned in the first accommodating cavity (312a), and when the closing valve (31) is closed, the upper surface of the closing plate (311) is attached to the inner wall of the upper part of the first accommodating cavity (312 a);

when the connecting device (4) is buckled with the closing valve (31), the closing plate (311) opens the closing valve (31) under the action of the connecting device (4).

Preferably, a second accommodating cavity (312b) is further arranged in the closed valve shell (312); the second accommodating cavity (312b) is positioned at the lower part of the first accommodating cavity (312a), and the first accommodating cavity (312a) and the second accommodating cavity (312b) are communicated with each other.

Preferably, the second containing cavity (312b) is spherical;

a floating ball (33) matched with the second accommodating cavity is arranged in the second accommodating cavity (312 b);

when the floating ball (33) floats upwards, the surface of the floating ball (33) is attached to the inner wall of the upper part of the second containing cavity (312b), and the first containing cavity (312a) and the second containing cavity (312b) are blocked.

Preferably, a connecting channel (41) is arranged in the connecting device (4);

the connecting device (4) is respectively connected with the one-way valve (21) and the closing valve (31) and then communicates the first liquid storage bag (2) and the second liquid storage bag (3) through a connecting channel (41).

Preferably, a mandril (411) is arranged at one end of the connecting channel (41) connected with the closing valve (31);

the ejector rod (411) is positioned on the inner side of one end of the connecting channel (41), the outer diameter of the ejector rod (411) is smaller than the inner diameter of the connecting channel (41), and the ejector rod (411) and the connecting channel (41) are coaxial;

after the connecting device (4) is connected with the closing valve (31), the ejector rod (411) pushes the closing plate (311) downwards.

Preferably, a return device is arranged between the lower part of the closing plate (311) and the inner wall of the first accommodating cavity (312 a).

Preferably, the outer diameter of the closing plate (311) is smaller than the inner diameter of the first accommodation cavity (312 a).

Preferably, the upper surface of the closing plate (311) is made of elastic material.

Preferably, the floating ball (33) is hollow.

Preferably, the connection portion (1) is a virtual bonding wire formed by hot pressing.

3. Advantageous effects

Compared with the prior art, the invention has the beneficial effects that:

the utility model provides a liquid storage bag for bio-pharmaceuticals liquid mixes, at the connecting portion through the rosin joint line of hot pressing formation, with the liquid medicine partial shipment of multiple differences in a liquid storage bag, connect through connecting device between two liquid storage bags, with the gas of one of them liquid storage bag arrange in another liquid storage bag, through increasing the atmospheric pressure in one of them liquid storage bag, strut the rosin joint line, solved effectively and can only be through pushing hard with the rosin joint line vaulting pole, improved work efficiency.

The second liquid storage bag is used for mixing the biological pharmaceutical liquid, the first liquid storage bag and the second liquid storage bag are respectively provided with a one-way valve and a closing valve which can be connected with a connecting device, external gas can only enter the first liquid storage bag through the control of the one-way valve, and the closing valve is connected with the connecting device and then enters the second liquid storage bag into the first liquid storage bag through the one-way valve, so that the pressure of the first liquid storage bag is increased.

Three, a stock solution bag for bio-pharmaceuticals liquid mixes, the second at the sealing valve casing holds the intracavity and installs the floater, after connecting device is connected with the sealing valve, gas in the second stock solution bag passes through in the connecting device flow direction first stock solution bag, except that gas can flow out, liquid also can discharge, the floater is located the second and holds the intracavity, can drive the floater come-up when liquid rises, hold the second and the first passageway that holds between the chamber is closed, make the liquid medicine can not flow in first stock solution bag through connecting device.

Drawings

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a cross-sectional view of the present invention;

FIG. 3 is a partial cross-sectional view of the connection device of the present invention;

FIG. 4 is a schematic view of the connection state of the present invention;

in the figure, 1, connecting part;

2. a first reservoir; 21. a one-way valve;

3. a second reservoir; 31. the closing valve 311, the closing plate 312, the closing valve shell 312, the first accommodating cavity 312b, the second accommodating cavity 33 and the floating ball;

4. a connecting device; 41. connecting channel 411, ejector pin.

Detailed Description

Example 1:

as shown in fig. 1-4, a reservoir for mixing biopharmaceutical liquids includes a connector portion 1 dividing the reservoir into at least two reservoirs sealed to each other. The connecting part 1 is a virtual welding line formed by hot pressing, and the liquid storage bag is divided into a plurality of liquid storage bags which are sealed relatively independently through the virtual welding line. In this embodiment, there are two separate reservoirs, a first reservoir 2 and a second reservoir 3. Wherein, the first reservoir 2 is provided with a one-way valve 21 flowing from the outside to the first reservoir 2, and the second reservoir 3 is provided with a closing valve 31 opening from the outside to the inside, so that the gas in the second reservoir 3 flows out. A connecting device 4 is connected between the first reservoir 2 and the second reservoir 3. Connecting device 4 one end fixed connection is on first reservoir 2, and the connecting device 4 other end is connected with 3 buckles of second reservoir, through connecting device 4 with

first reservoir

2 and 3 intercommunications of second reservoir, with the gaseous first reservoir 2 of arranging in the second reservoir 3, the pressure increase of first reservoir 2 props open connecting portion 1 of rosin joint between first reservoir 2 and the second reservoir 3, and the liquid medicine of first reservoir 2 and second reservoir 3 realizes mixing.

Specifically, the latching valve 31 includes a latching plate 311 and a latching valve housing 312. A first accommodating cavity 312a is arranged in the closing valve housing 312, the closing plate 311 is located in the first accommodating cavity 312a, when the closing valve 31 is closed, the upper surface of the closing plate 311 is attached to the inner wall of the upper portion of the first accommodating cavity 312a, and when the connecting device 4 is buckled with the closing valve 31, the closing plate 311 opens the closing valve 31 under the action of the connecting device 4. A second receiving chamber 312b is also provided in the closing valve housing 312. The second receiving chamber 312b is located at a lower portion of the first receiving chamber 312a, and the first receiving chamber 312a and the second receiving chamber 312b communicate with each other.

Specifically, the second accommodating cavity 312b is spherical, a floating ball 33 matched with the second accommodating cavity is arranged in the second accommodating cavity 312b, the floating ball 33 is hollow, and when the floating ball 33 floats upwards, the surface of the floating ball 33 is attached to the inner wall of the upper portion of the second accommodating cavity 312b, so that the first accommodating cavity 312a and the second accommodating cavity 312b are blocked.

Specifically, a connecting channel 41 is arranged in the connecting device 4, and after the connecting device 4 is connected with the one-way valve 21 and the closing valve 31 respectively, the first reservoir 2 and the second reservoir 3 are communicated through the connecting channel 41. An ejector rod 411 is arranged at one end of the connecting channel 41 connected with the closing valve 31, the ejector rod 411 is positioned on the inner side of one end of the connecting channel 41, the outer diameter of the ejector rod 411 is smaller than the inner diameter of the connecting channel 41, the ejector rod 411 and the connecting channel 41 are coaxial, and after the connecting device 4 is connected with the closing valve 31, the ejector rod 411 pushes the closing plate 311 downwards.

Specifically, a return device is arranged between the lower portion of the closing plate 311 and the inner wall of the first accommodating cavity 312a, and after the connecting device 4 is disconnected from the closing valve 31 by the return device, the closing plate 311 is jacked up under the action of the return device and attached to the inner wall of the first accommodating cavity 312a to close the closing valve 31.

Specifically, the outer diameter of the closing plate 311 is smaller than the inner diameter of the first accommodating cavity 312a, and the closing plate 311 moves up and down in the first accommodating cavity 312 a. To increase the sealing effect, the upper surface of the closing plate 311 is made of a material having elasticity.

When not using state, the one end of connecting device 4 is connected with first reservoir 2, other one end free state, when needing to mix the liquid medicine of first reservoir 2 and second reservoir 3, go into the free port of connecting device 4 in the port of closing valve 31, ejector pin 411 promotes the downward motion of closing plate 311, make connecting channel 41 and the first chamber 312a that holds communicate, pat second reservoir 3 gently, pass through connecting channel 41 with the gas in the second reservoir 3 and emit into in the first reservoir 2, increase the atmospheric pressure in the first reservoir 2, make connecting portion 1 of rosin joint prop open, reach the unnecessary liquid medicine of first reservoir 2 and second reservoir 3 and mix.

Example 2:

on the basis of embodiment 1, the connecting device 4 and the liquid storage bag are separated, the ports at two ends of the connecting device 4 are connected with the dustproof caps, the connecting device is opened when in use, the dustproof caps are also arranged on the one-way valve 21 and the sealing valve 31, and the dustproof caps are taken off when being connected with the connecting device 4, so that the pollution of a connecting port is effectively prevented.

Claims

1. A reservoir bag for mixing biopharmaceutical liquids, comprising a connecting portion (1) dividing the reservoir bag into at least two mutually sealed reservoirs;

2. A reservoir bag for mixing biopharmaceutical liquids as in claim 1 wherein a second receiving cavity (312b) is further provided in said closure valve housing (312); the second accommodating cavity (312b) is positioned at the lower part of the first accommodating cavity (312a), and the first accommodating cavity (312a) and the second accommodating cavity (312b) are communicated with each other.

3. A reservoir bag for mixing of biopharmaceutical liquids as in claim 2 wherein said second cavity (312b) is spherical;

4. A reservoir bag for mixing of biopharmaceutical liquids according to claim 1, wherein a connection channel (41) is provided in said connection device (4);

5. A reservoir bag for mixing of biopharmaceutical liquids according to claim 4 wherein an end of said connection channel (41) connected to said closing valve (31) is provided with a push rod (411);

6. A reservoir bag for mixing biopharmaceutical liquids according to claim 1, wherein return means are provided between a lower portion of said closure plate (311) and an inner wall of said first cavity (312 a).

7. A reservoir bag for mixing of biopharmaceutical liquids according to claim 1, wherein an outer diameter of said closure plate (311) is smaller than an inner diameter of said first receiving cavity (312 a).

8. A reservoir bag for mixing of biopharmaceutical liquids according to claim 1, wherein an upper surface of said closure plate (311) is of a material having elasticity.

9. A reservoir bag for mixing biopharmaceutical liquids as in claim 2 wherein said floating ball (33) is hollow.

10. A reservoir bag for mixing of biopharmaceutical liquids according to claim 1 wherein said connection portion (1) is a virtual weld line formed by heat pressing.