CN113058144B - Nasal cavity circulation drug delivery device - Google Patents
Nasal cavity circulation drug delivery device Download PDFInfo
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- CN113058144B CN113058144B CN202110520133.1A CN202110520133A CN113058144B CN 113058144 B CN113058144 B CN 113058144B CN 202110520133 A CN202110520133 A CN 202110520133A CN 113058144 B CN113058144 B CN 113058144B
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- storage cavity
- circulation
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- 210000003928 nasal cavity Anatomy 0.000 title claims abstract description 52
- 238000012377 drug delivery Methods 0.000 title claims abstract description 34
- 239000007788 liquid Substances 0.000 claims abstract description 106
- 210000003128 head Anatomy 0.000 claims abstract description 67
- 239000011550 stock solution Substances 0.000 claims abstract description 42
- 239000003814 drug Substances 0.000 claims abstract description 27
- 238000001802 infusion Methods 0.000 claims abstract description 18
- 238000001914 filtration Methods 0.000 claims abstract description 4
- 239000007921 spray Substances 0.000 claims description 12
- 230000008878 coupling Effects 0.000 claims 1
- 238000010168 coupling process Methods 0.000 claims 1
- 238000005859 coupling reaction Methods 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 abstract description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 6
- 229940079593 drug Drugs 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 210000001331 nose Anatomy 0.000 description 4
- 238000000034 method Methods 0.000 description 3
- 238000007789 sealing Methods 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000009513 drug distribution Methods 0.000 description 2
- 210000000492 nasalseptum Anatomy 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 235000015073 liquid stocks Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002351 wastewater Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2210/00—Anatomical parts of the body
- A61M2210/06—Head
- A61M2210/0618—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a nasal cavity circulation drug delivery device, which comprises a shell, a liquid storage tank, a drug delivery mechanism and a circulation mechanism, wherein the liquid storage tank is arranged on the shell; the liquid storage tank is divided into a stock solution storage cavity and a liquid return storage cavity, and a one-way valve is arranged between the stock solution storage cavity and the liquid return storage cavity; the drug delivery mechanism comprises a drug delivery nozzle, a drug delivery pump, a first infusion pipeline and a second infusion pipeline, and liquid in the stock solution storage cavity is pumped to the drug delivery nozzle by the drug delivery pump; the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline and a second liquid return pipeline, and liquid sucked by the suction head is pumped to the liquid return storage cavity by the circulating pump; the liquid pumped by the suction head flows back to the stock solution storage cavity from the liquid return storage cavity through the one-way valve after being filtered by the filtering component. According to the technical scheme provided by the invention, the effective residence time and the distribution space of the liquid medicine in the nasal cavity are improved through cyclic administration, so that the medicine is absorbed, and the nasal cavity is effectively prevented from being choked and damaged by water pressure.
Description
Technical Field
The invention relates to the technical field of medical treatment and health, in particular to a nasal cavity circulation drug delivery device.
Background
At present, the benefits of drug absorption through nasal mucosa are agreed in the medical field, and the nasal drug absorption and utilization rate and drug distribution capacity are not high due to the functional limitations of nasal structures and drug delivery systems.
Disclosure of Invention
The invention aims to improve the absorption and utilization rate and the drug distribution capacity of nasal administration.
The invention in order to achieve the above object, the present invention provides a nasal cavity circulation drug delivery device comprising a housing, and a liquid storage tank, a drug delivery mechanism and a circulation mechanism mounted on the housing;
the liquid storage tank is internally divided into a stock solution storage cavity and a liquid return storage cavity, a one-way valve is arranged between the stock solution storage cavity and the liquid return storage cavity, and the one-way valve is arranged in such a way that the liquid medicine in the liquid return storage cavity can flow to the stock solution storage cavity;
the dosing mechanism comprises a dosing spray head, a dosing pump, a first infusion pipeline connected between the stock solution storage cavity and the dosing pump, and a second infusion pipeline connected between the dosing pump and the dosing spray head, wherein liquid in the stock solution storage cavity can be pumped to the dosing spray head by the dosing pump to be sprayed out;
the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline connected between the suction head and the circulating pump, and a second liquid return pipeline connected between the liquid return storage cavity and the circulating pump, wherein liquid sucked by the suction head is pumped to the liquid return storage cavity through the circulating pump;
the liquid pumped by the suction head flows back to the stock solution storage cavity through the one-way valve from the liquid return storage cavity after being filtered by the filtering component.
Preferably, an exhaust valve for keeping the balance of the internal and external air pressures of the stock solution storage cavity is arranged on the side wall of the stock solution storage cavity.
Preferably, the delivery head and the suction head are fixed relative to the housing, and the delivery head and the suction head are arranged such that when the delivery head is inserted into one nostril of a human body, the suction head can be inserted into the other nostril.
Preferably, the upper end of the shell is provided with a first interface and a second interface, and the lower end of the shell is provided with a first opening and a second opening;
the administration spray head is arranged at the first interface, the suction head is arranged at the second interface, and the administration pump and the circulating pump are arranged in the cavity of the shell;
the liquid storage tank is detachably arranged below the shell, and is provided with a first opening which is communicated with the stock solution storage cavity and corresponds to the first opening, and a second opening which is communicated with the liquid return storage cavity and corresponds to the second opening.
Preferably, the administration pump of the administration mechanism is mounted in the housing, and the administration nozzle is connected to an end of the second infusion line extending outside the housing, wherein at least a portion of the line of the second infusion line located outside the housing is flexible to enable the administration nozzle to move relative to the housing; and/or the number of the groups of groups,
the circulating pump of the circulating mechanism is arranged in the shell, the suction head is connected to one end of the first liquid return pipeline, which is positioned outside the shell, wherein at least part of the pipeline of the first liquid return pipeline, which is positioned outside the shell, is flexible so that the suction head can move relative to the shell.
Preferably, the nasal circulation administration device further comprises a connecting member arranged to connect to the head or ear when the administration nozzle and/or the suction head is inserted into the nasal cavity, to prevent the administration nozzle and/or the suction head from being detached from the nasal cavity.
Preferably, the nasal circulation drug delivery device further comprises a control unit connected with the drug delivery pump and the circulation pump and a control switch connected with the control unit;
the control unit is arranged to start the circulation pump and the administration pump simultaneously when the control switch is started; and
the control unit is arranged to stop the drug delivery pump when the control switch is closed, and stop the suction pump after the suction pump continues to work for a preset time; or the control switch has a first closing state and a second closing state, and the control unit is set so that when the control switch is in the first closing state, the administration pump stops working, and the suction pump continues to work, and when the control switch is in the second closing state, the administration pump and the suction pump stop working.
Preferably, the administration pump and the circulation pump are miniature diaphragm pumps.
Preferably, the nasal circulation administration device further comprises a first cover over the administration nozzle and a second cover for over the suction nozzle.
The technical scheme provided by the invention can realize the cyclic administration of the nasal cavity, thereby improving the effective residence time and the distribution space of the liquid medicine in the nasal cavity and being beneficial to the absorption and utilization rate of the medicine. Meanwhile, when the nasal cavity on one side is circularly administrated, negative pressure traction is generated by sucking the nasal cavity on the other side, so that the problems of nasal cavity choking and nasal cavity damage caused by water pressure in the nasal cavity when the nasal cavity is administrated in the prior art can be effectively avoided.
Drawings
The accompanying drawings, which are included to provide a further understanding of the invention, illustrate and explain the invention and are not to be construed as limiting the invention. In the drawings:
FIG. 1 is a schematic view of a nasal circulation administration device according to one embodiment of the present invention;
FIG. 2 is a schematic view of a nasal circulation administration device from another perspective;
FIG. 3 is a schematic view of the internal structure of the nasal circulation administration device;
FIG. 4 is a schematic illustration of the power cord plugged into the nasal circulation administration device;
FIG. 5 is a schematic circuit diagram of a nasal circulation administration device;
FIG. 6 is a schematic illustration of the injection of a liquid medicine into the stock solution storage chamber after the tank is removed from the housing;
FIG. 7 is a schematic view of pouring the waste water from the liquid return storage chamber after the liquid storage tank is detached from the housing;
fig. 8 is a schematic view of the structure of a human nose;
FIG. 9 is another structural illustration of a human nose;
FIG. 10 is a schematic illustration of nasal cavity cleansing using a nasal circulatory delivery device provided in one embodiment;
fig. 11 is a schematic view of nasal cavity cleansing using a nasal circulatory delivery device provided in another embodiment.
Description of the reference numerals
1-a drug delivery mechanism; 11-a spray head; 12-an administration pump; 13-a first infusion line; 14-a second infusion line; 2-a circulation mechanism; 21-sucking head; 22-a circulation pump; 23-a first liquid return pipeline; 24-a second liquid return pipeline; 3-a housing; 31-a first interface; 32-a second interface; 33-a first opening; 34-a second opening; 35-a first seal; 36-a second seal; 4-a liquid storage tank; 41-a stock solution storage chamber; 42-a liquid return storage cavity; 43-one-way valve; 44-a filter element; 45-exhaust valve; 5-controlling a switch; 51-switching a display lamp; 6-cell; 7-a first cover; 8-a second cover; 9-a circuit board; 10-a charging interface; 20-power supply lines; 30-connecting parts; 100-head; 101-nose; 102-nasal septum; 103-first nostril; 104-a first nasal meatus; 105-a second naris; 106-a second nasal meatus; 107-posterior naris.
Detailed Description
Example embodiments will now be described more fully with reference to the accompanying drawings. However, the exemplary embodiments may be embodied in many forms and should not be construed as limited to the examples set forth herein; rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the concept of the example embodiments to those skilled in the art. The drawings are merely schematic illustrations of the present disclosure and are not necessarily drawn to scale. The same reference numerals in the drawings denote the same or similar parts, and thus a repetitive description thereof will be omitted.
Furthermore, the described features, structures, or characteristics may be combined in any suitable manner in one or more embodiments. In the following description, numerous specific details are provided to give a thorough understanding of embodiments of the present disclosure. One skilled in the relevant art will recognize, however, that the aspects of the disclosure may be practiced without one or more of the specific details, or with other methods, components, devices, steps, etc. In other instances, well-known structures, methods, devices, implementations, materials, or operations are not shown or described in detail to avoid obscuring aspects of the disclosure.
Spatially relative terms, such as "upper," "lower," "left," "right," and the like, may be used herein for ease of description to describe one element or feature's relationship to another element or feature's illustrated in the figures. It will be understood that the spatial terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "under" other elements or features would then be oriented "over" the other elements or features. Thus, the exemplary term "lower" may encompass both an upper and lower orientation. The device may also be otherwise positioned, such as rotated 90 degrees or at other orientations, and the spatially relative descriptors used herein interpreted accordingly.
The invention provides a nasal cavity circulation drug delivery device, as shown in figures 1-4, which comprises a shell 3, a liquid storage tank 4, a drug delivery mechanism 1 and a circulation mechanism 2, wherein the liquid storage tank 4, the drug delivery mechanism 1 and the circulation mechanism 2 are arranged on the shell 3;
the liquid storage tank 4 is internally divided into a stock solution storage cavity 41 and a liquid return storage cavity 42, a one-way valve 43 is arranged between the stock solution storage cavity 41 and the liquid return storage cavity 42, and the one-way valve 43 is arranged in such a way that the liquid medicine in the liquid return storage cavity 42 can only flow to the stock solution storage cavity 41;
the dosing mechanism 1 comprises a dosing nozzle 11, a dosing pump 12, a first infusion pipeline 13 connected between the stock solution storage cavity 41 and the dosing pump 12, and a second infusion pipeline 14 connected between the dosing pump 12 and the dosing nozzle 11, wherein the liquid in the stock solution storage cavity 31 can be pumped to the dosing nozzle 11 by the dosing pump 12 for ejection;
the circulating mechanism 2 comprises a suction head 21, a circulating pump 22, a first liquid return pipeline 23 connected between the suction head 21 and the circulating pump 22, and a second liquid return pipeline 24 connected between the liquid return storage cavity 42 and the circulating pump 22, wherein the liquid sucked by the suction head 21 is pumped to the liquid return storage cavity 42 through the circulating pump 22;
wherein, a filter member 44 is disposed in the liquid return storage chamber 42, the liquid pumped by the suction head 21 is filtered by the filter member 44, and flows back from the liquid return storage chamber 42 to the stock solution storage chamber 41 through the one-way valve 43, and the liquid in the stock solution storage chamber 41 is sprayed to the nasal cavity.
Preferably, an exhaust valve 45 for maintaining the balance of the internal and external air pressures of the stock solution storage chamber 41 is provided on the sidewall of the stock solution storage chamber 41. By providing the vent valve 45, it is ensured that the liquid in the liquid return storage chamber 42 can enter the stock solution storage chamber 41 through the check valve 43.
When the nasal cavity circulation drug delivery device provided by the invention is used, the drug delivery spray head 11 and the suction head 21 are respectively inserted into one nasal cavity, so that the controllable drug delivery of the drug delivery spray head 11 to one nasal cavity can be realized, meanwhile, the liquid medicine flowing out of the other nasal cavity is sucked through the suction head 21, then the sucked liquid medicine filters nasal secretion wrapped in the liquid medicine through the filtering component 44, and the sucked liquid medicine enters the stock solution storage cavity 41 through the one-way valve 43 after being sucked, and is sprayed to the nasal cavity again through the drug delivery spray head 11 from the stock solution storage cavity 41, thereby realizing the nasal cavity circulation drug delivery, solving the problem that the nasal cavity is hurt by the water choking and the water pressure in the nasal cavity when the nasal cavity is administrated in the prior art, improving the effective residence time and the distribution space of the liquid medicine in the nasal cavity, and being beneficial to the absorption utilization rate of the drug.
The nasal circulation administration device provided by the invention is described in detail below according to the embodiment.
First embodiment
In this first embodiment, the administration nozzle 11 and the administration pump 12 in the administration mechanism 1 and the suction nozzle 21 and the circulation pump 22 in the circulation mechanism 2 are fixed to the housing.
In this embodiment, the administration nozzle 11 and the suction nozzle 21 are fixed with respect to the housing 3, and the administration nozzle 11 and the suction nozzle 21 are configured such that, when the administration nozzle 11 is inserted into one nostril of a human body for cyclic administration, the suction nozzle 21 can be inserted into the other nostril for suction.
Specifically, as shown in fig. 1 to 3, the upper end of the housing 3 of the nasal circulation administration device is provided with a first port 31 and a second port 32, and the lower end is provided with a first opening 33 and a second opening 34;
the administration nozzle 11 is fixedly installed at the first port 31, the administration pump 12 is installed in the cavity of the housing 3, the suction head 21 is fixedly installed at the second port 32, and the circulation pump 22 is installed in the cavity of the housing 3.
The liquid storage tank 4 is detachably mounted below the housing 3, and the liquid storage tank 4 has a first opening which is communicated with the stock solution storage cavity 41 and corresponds to the first opening 33, and a second opening which is communicated with the liquid return storage cavity 42 and corresponds to the second opening 34, a first infusion pipeline 13 connected with the water inlet of the administration pump 12 extends into the stock solution storage cavity 41 through the first opening 33, and a second liquid return pipeline 24 connected with the water outlet of the circulation pump 22 extends into the liquid return storage cavity 42 through the second opening 34.
As shown in fig. 3 and 4, a first sealing member 35 for sealing the connection between the first opening of the liquid storage tank 4 and the first liquid delivery line 13 is provided at the first opening 33; a second seal 36 is provided at the second opening 34 for sealing the connection between the second opening of the tank 4 and the second return line 24.
Preferably, the reservoir 4 is arranged to be detachably mounted on the housing 3. Fig. 6 shows the tank 4 removed from the housing 3, and the tank 4 is attached to the housing 3 after being filled with the liquid medicine circulated into the liquid stock chamber 41, and fig. 7 shows the tank 4 removed from the housing 3 after use, and the liquid in the liquid return chamber 42 is removed.
The nasal circulation administration device further comprises a first cover 7 for covering the administration nozzle 11 and a second cover 8 for covering the suction nozzle 21. When the novel medicine feeder is used, the first cover body 7 and the second cover body 8 are taken down, and after the novel medicine feeder is used, the first cover body 7 and the second cover body 8 are covered to protect the medicine feeding nozzle 11 and the suction head 21.
The battery 6 is provided in the housing 3, and the battery 6 may be provided between the drug delivery pump 12 and the circulation pump 22 as shown in fig. 3, but may be provided in other positions. The housing 3 is provided with a charging interface 10 for charging the battery 6. As shown in fig. 4, the battery 6 can be charged by connecting a power line 20 (in this embodiment, a power line of a USB interface) to the charging interface 10.
In addition, the control switch 5 for controlling the nasal circulation administration device is provided at a position suitable for operation on the housing 3, and a switch indication lamp 51 for indicating the on-off state of the control switch 5 is also provided on the housing 3. The switch indicator lamp 51 is turned on when the control switch 5 is in the on state, and the switch indicator lamp 51 is turned off when the control switch 5 is in the off state.
In this embodiment, for convenience of control of the administration mechanism 1 and the circulation mechanism 2, the nasal cavity circulation administration device further includes a control unit connected to the administration pump 12 and the circulation pump 22, and a control switch 5 connected to the control unit. The control unit is in particular a circuit board 9 as shown in fig. 3 and 5. Fig. 5 shows a schematic circuit diagram of the nasal circulation administration device.
The control unit is arranged to activate both the suction pump 22 and the dosing pump 12 at the same time when the control switch 5 is activated;
in order to ensure that the medicine is sucked by the circulation mechanism 2 to leave the nasal cavity after the nasal cavity circulation medicine feeder is used, no medicine remains in the nasal cavity, namely, only the circulation mechanism 2 works after the medicine feeding mechanism 1 stops working. The control unit is arranged to stop the administration pump 12 first when the control switch 5 is closed, and to stop the suction pump 22 after a predetermined time of continued operation. Alternatively, the control switch 5 is set to have a first off state and a second off state, and the control unit is set such that the administration pump 12 stops operating and the suction pump 22 continues to operate when the control switch 5 is in the first off state, and such that both the administration pump 12 and the suction pump 22 stop operating when the control switch 5 is in the second off state. This ensures that no drug remains in the nasal cavity after the end of the cyclic administration, and the drug is finally stored in the stock solution storage tank 42.
The first closing state may be a state in which the switch 5 is closed after being pressed only once, and the second closing state may be a state in which the switch 5 is closed after being pressed twice. Of course, the first closing state and the second closing state may take other forms, for example, the control switch 5 may be provided to include two control switches, where one control switch is in the first closing state when closed, and the other control switch is in the second closing state when closed.
Second embodiment
In this second embodiment, referring to fig. 11, the administration pump 12 of the administration mechanism 1 is installed in the housing 3, the administration nozzle 11 is connected to an end of the second infusion line 14 extending outside the housing 3, wherein at least a portion of the line of the second infusion line 14 located outside the housing 3 is flexible to enable the administration nozzle 11 to move relative to the housing 3; and/or the number of the groups of groups,
the circulating pump 22 of the circulating mechanism 2 is installed in the housing 3, and the suction head 21 is connected to one end of the first liquid return pipeline 23 located outside the housing 3, wherein at least part of the pipeline of the first liquid return pipeline 23 located outside the housing 3 is flexible so that the suction head 21 can move relative to the housing 3.
The mounting of the administration pump 12 of the administration mechanism 1 and the circulation pump 22 of the circulation mechanism 2 in the housing 3 and the mounting of the tank 4 in the present embodiment may be the same as those in the above embodiment, except that the administration nozzle 11 and the suction nozzle 21 are flexibly connected to the outside of the housing 3 so as to be movable with respect to the housings 3. In this way, when using the nasal circulation administration device, the administration nozzle 11 and the suction head 21 can be simply held by hand and inserted into the nasal cavity, which is light.
Preferably, the nasal circulation administration device further comprises a connection member 30, the connection member 30 being arranged to be connected to the head or the ear when the administration nozzle 11 and/or the suction head 21 are inserted into the nasal cavity, so as to prevent the administration nozzle and/or the suction head from being detached from the nasal cavity. For example, the connection member 30 may be an ear-hanging or head-hanging string connected to the administration head and the suction head, and the administration head 11 and the suction head 21 may be prevented from being separated from the nasal cavity by being hung on the ear or the head-hanging string connected to the head when the administration head 11 and the suction head 21 are respectively inserted into the nasal cavity, thus facilitating the liberation of both hands.
The charging and control manner in the second embodiment may be the same as that in the first embodiment, and will not be described here again.
The following describes a specific procedure for cleaning the nasal cavity using the nasal circulation administration device.
Figures 8 and 9 show the structure of the human head 100 at the nose, on the medial line of the interior of the nose 101 of the head 100 is a nasal septum 102, 2 nasal passages being located on each side of the nasal septum 102, namely a first nasal passage 104 communicating with a first nostril 103 and a second nasal passage 106 communicating with a second nostril 105, the first nasal passage 104 and the second nasal passage 106 communicating at a posterior nostril 107 throughout the rear of the nasal cavity, liquid can flow between the first nasal passage 104 and the second nasal passage 106 through the posterior nostril 107, so that liquid entering from the first nostril 103 can flow out of the second nostril 105 through the first nasal passage 104, the posterior nostril 107 and the second nasal passage 106 in sequence.
Fig. 10 shows a state in which the administration mechanism 1 and the circulation mechanism 2 of the nasal cavity circulation administration device are simultaneously operated to administer drugs to the nasal cavity, and the nasal cavity circulation administration device shown in fig. 10 is provided as the above-described first embodiment.
When in use, the liquid storage tank 4 is firstly arranged on the shell 3, and the first cover body 7 and the second cover body 8 are removed to expose the administration nozzle 11 and the suction head 21;
the administration nozzle 11 is inserted into the first nostril 103, and the suction nozzle 21 is inserted into the second nostril 105;
the control switch 5 is turned on, the administration pump 12 and the circulating pump 22 are simultaneously started, the administration pump 12 pumps the liquid in the stock solution storage cavity 41 to the first nostril 103, the liquid entering the first nasal passages 104 from the first nostril 103 can enter the second nasal passages 105 from the rear nostril 107, then the liquid flowing out from the opposite nasal passages is sucked and discharged by the sucking head 21 positioned in the second nostril 105 along the first liquid return pipeline 23, the circulating pump 22 and the second liquid return pipeline 24 into the liquid return storage cavity 42 while the liquid is administrated to the nasal cavity. The sucked and discharged liquid is filtered by the filter member 44, enters the stock solution storage chamber 41 through the check valve 43, and is then delivered from the stock solution storage chamber 41 to the nasal cavity through the administration nozzle 11.
After the circulation dosing is completed, the control switch 5 is turned off, at this time, the dosing pump 12 stops working, and the circulation pump 22 stops after continuing to suck for a while.
Fig. 11 shows a schematic view of cyclic administration of nasal cavities using the nasal cyclic administration device provided in the second embodiment described above. The drug delivery nozzle 11 is shown connected to the outside of the housing 3 through a flexible second infusion line 14 and the suction head 12 through a flexible first return line 23, and is connected to the head 100 through a connecting member 30 when the drug delivery nozzle 11 and the suction head 12 are inserted into two nostrils, respectively, so that the drug delivery nozzle 11 and the suction head 12 can be prevented from being separated from the nostrils. The specific operation of the nasal circulation administration device in this embodiment is the same as that of the above embodiment.
The preferred embodiments of the present invention have been described in detail above with reference to the accompanying drawings, but the present invention is not limited thereto. Within the scope of the technical idea of the invention, a number of simple variants of the technical solution of the invention are possible, including combinations of individual specific technical features in any suitable way. The various possible combinations of the invention are not described in detail in order to avoid unnecessary repetition. Such simple variations and combinations are likewise to be regarded as being within the scope of the present disclosure.
Claims (9)
1. The nasal cavity circulation drug delivery device is characterized by comprising a shell, a liquid storage tank, a drug delivery mechanism and a circulation mechanism, wherein the liquid storage tank, the drug delivery mechanism and the circulation mechanism are arranged on the shell;
the liquid storage tank is internally divided into a stock solution storage cavity and a liquid return storage cavity, a one-way valve is arranged between the stock solution storage cavity and the liquid return storage cavity, and the one-way valve is arranged in such a way that the liquid medicine in the liquid return storage cavity can flow to the stock solution storage cavity; wherein the liquid storage tank is detachably arranged on the shell;
the dosing mechanism comprises a dosing spray head, a dosing pump, a first infusion pipeline connected between the stock solution storage cavity and the dosing pump, and a second infusion pipeline connected between the dosing pump and the dosing spray head, wherein liquid in the stock solution storage cavity can be pumped to the dosing spray head by the dosing pump to be sprayed out;
the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline connected between the suction head and the circulating pump, and a second liquid return pipeline connected between the liquid return storage cavity and the circulating pump, wherein liquid sucked by the suction head is pumped to the liquid return storage cavity through the circulating pump;
the liquid pumped by the suction head flows back to the stock solution storage cavity through the one-way valve from the liquid return storage cavity after being filtered by the filtering component.
2. The nasal circulation dosing device of claim 1, wherein an exhaust valve for maintaining the balance of the internal and external air pressures of the stock solution storage chamber is provided on a side wall of the stock solution storage chamber.
3. The nasal circulation dosing device of claim 1, wherein the dosing head and the suction head are fixed relative to the housing and the dosing head and suction head are configured such that when the dosing head is inserted into one nostril of a human body, the suction head is insertable into the other nostril.
4. The nasal circulation dosing device of claim 3, wherein the housing has a first port and a second port at an upper end and a first aperture and a second aperture at a lower end;
the administration spray head is arranged at the first interface, the suction head is arranged at the second interface, and the administration pump and the circulating pump are arranged in the cavity of the shell;
the liquid storage tank is detachably arranged below the shell, and is provided with a first opening which is communicated with the stock solution storage cavity and corresponds to the first opening, and a second opening which is communicated with the liquid return storage cavity and corresponds to the second opening.
5. The nasal circulation dosing device of claim 1, wherein the dosing pump of the dosing mechanism is mounted within the housing, the dosing cap being connected to an end of the second infusion line that extends outside the housing, wherein at least a portion of the line of the second infusion line that is outside the housing is flexible to enable movement of the dosing cap relative to the housing; and/or the number of the groups of groups,
the circulating pump of the circulating mechanism is arranged in the shell, the suction head is connected to one end of the first liquid return pipeline, which is positioned outside the shell, wherein at least part of the pipeline of the first liquid return pipeline, which is positioned outside the shell, is flexible so that the suction head can move relative to the shell.
6. The nasal circulation dosing device of claim 5, further comprising a coupling member configured to couple to a head or ear when the dosing and/or suction head is inserted into the nasal cavity to prevent the dosing and/or suction head from being removed from the nasal cavity.
7. The nasal circulation dosing device of any one of claims 1-6, further comprising a control unit coupled to the dosing pump and the circulation pump and a control switch coupled to the control unit;
the control unit is arranged to start the circulation pump and the administration pump simultaneously when the control switch is started; and
the control unit is arranged to stop the drug delivery pump when the control switch is closed, and stop the circulating pump after the circulating pump continues to work for a preset time; or the control switch has a first closing state and a second closing state, and the control unit is set so that when the control switch is in the first closing state, the administration pump stops working, the circulating pump continues to work, and when the control switch is in the second closing state, the administration pump and the circulating pump stop working.
8. The nasal circulation dosing device of any one of claims 1-6, wherein the dosing pump and the circulation pump are miniature diaphragm pumps.
9. The nasal circulation dosing device of any one of claims 1-6, further comprising a first cap over the dosing head and a second cap for over the suction head.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110520133.1A CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202110520133.1A CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN113058144A CN113058144A (en) | 2021-07-02 |
| CN113058144B true CN113058144B (en) | 2024-01-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202110520133.1A Active CN113058144B (en) | 2021-05-13 | 2021-05-13 | Nasal cavity circulation drug delivery device |
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| CN113730779B (en) * | 2021-11-05 | 2022-02-08 | 纳索菲德(上海)制药技术有限公司 | Device for spraying medicine to nasal cavity and using method |
| CN114470496B (en) * | 2022-01-14 | 2024-04-12 | 赵子逸 | Nasal and olfactory region circulation drug delivery device |
| CN115282412B (en) * | 2022-01-14 | 2023-08-25 | 温州医科大学 | Drug delivery device for entering blood circulation through nasal cavity and application method thereof |
| CN116898717A (en) * | 2023-09-13 | 2023-10-20 | 暨甄(北京)科技有限公司 | Nasal cavity nursing device |
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