CN112945957B - High-precision microscopic scanning platform capable of automatically loading slide - Google Patents
High-precision microscopic scanning platform capable of automatically loading slide Download PDFInfo
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- CN112945957B CN112945957B CN202110171475.7A CN202110171475A CN112945957B CN 112945957 B CN112945957 B CN 112945957B CN 202110171475 A CN202110171475 A CN 202110171475A CN 112945957 B CN112945957 B CN 112945957B
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- 230000007246 mechanism Effects 0.000 claims abstract description 110
- 239000011521 glass Substances 0.000 claims abstract description 45
- 230000000007 visual effect Effects 0.000 claims description 12
- 238000007598 dipping method Methods 0.000 claims description 9
- 238000006243 chemical reaction Methods 0.000 description 6
- 238000004043 dyeing Methods 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001360 synchronised effect Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/24—Base structure
- G02B21/26—Stages; Adjusting means therefor
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- G—PHYSICS
- G02—OPTICS
- G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
- G02B21/00—Microscopes
- G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
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Abstract
The invention relates to a high-precision microscopic scanning platform for automatically loading slides, which comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis lead screw nut mechanism; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw nut mechanism, and the X-axis movable plate is slidably assembled on the Z-axis screw nut mechanism; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism, and the Y-axis movable plate is slidably assembled in the X-axis screw nut mechanism; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding way; the glass slide table is provided with a slide positioning groove for inserting a slide, the bottom of the slide positioning groove is provided with an avoidance groove, and the avoidance groove is communicated in the slide inserting direction. The invention can rapidly and automatically load the slide, the triaxial mechanism rapidly and accurately sends the slide to the scanning position, the objective lens can be rapidly switched at any time according to the type of the slide, the automation degree is high, the positioning is accurate, the speed is high, and the invention can adapt to the requirement of large-scale continuous scanning.
Description
Technical Field
The invention relates to the technical field of slide scanning detection, in particular to a high-precision microscopic scanning platform for automatically loading slides.
Background
The automation degree of slide sample scanning is higher and higher, and slide sample's film-making, dyeing, scanning link all have automatic equipment, have improved slide scanning efficiency, have reduced personnel's infection risk, but slide scanning link still has some problems, like the full-automatic film-making dyeing scanning system (with the present applicant) that the invention patent of publication number CN111551756A discloses, can realize film-making, dyeing, the automation of scanning, slide scanning link adopts the manipulator to snatch the slide from the slide box and scans, and the slide position can be adjusted in the glass stand horizontal movement about. However, the position of the sample on the slide has deviation, and a part of the slide sample still cannot be scanned comprehensively after the position of the glass carrier is adjusted, so that a certain scanning blind area exists. Different types of slide samples also need to be scanned by using different types of scanning objective lenses, and some scanning devices capable of adjusting the objective lenses are available on the market, for example, a full-automatic microscope scanning system without an objective table disclosed in the patent of publication number CN107479178A adopts a synchronous belt to switch the objective lenses to scan different types of slide samples, so that the rotation precision cannot be ensured, and the synchronous belt needs an additional driving mechanism to drive, so that a plurality of parts are added, and the volume of the scanning device is increased. The manipulator device capable of freely grabbing the slide disclosed in the patent publication No. CN110587585A adopts a plurality of groups of screw nut mechanisms and electric clamping jaws to clamp and transfer the slide, has a complex structure and low slide transferring efficiency, occupies equipment space, can generate more vibration in the operation process, and influences the detection result of the slide.
Disclosure of Invention
The invention aims to provide a high-precision microscopic scanning platform for automatically loading slides, which solves the problems that the existing slide scanning link cannot adapt to different types of slides for scanning and has low scanning efficiency.
In order to achieve the above purpose, the invention adopts the following technical scheme:
a high-precision microscopic scanning platform for automatically loading slides comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis lead screw nut mechanism arranged on the Z-axis fixing plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw nut mechanism in a sliding way; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is slidably assembled in the X-axis screw nut mechanism; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding way; the glass slide positioning device is characterized in that a glass slide positioning groove for inserting a glass slide is formed in the glass slide table, an avoidance groove is formed in the bottom of the glass slide positioning groove, and the avoidance groove is communicated in the glass slide inserting direction.
Further preferably, a slide position sensor is provided in the slide positioning groove.
Further preferably, the slide positioning groove is provided with a pushing mechanism at one side for inserting a slide, and the pushing mechanism comprises a slide pushing plate for pushing the slide into the slide positioning groove from the slide box, a slide reset pushing plate for pushing the slide back into the slide box from the slide positioning groove, and a pushing mechanism supporting plate, wherein the slide pushing plate and the slide reset pushing plate are respectively arranged at two ends of the pushing mechanism supporting plate.
Further preferably, the slide pushing plate and the slide reset pushing plate are horizontally arranged at the same height.
Further preferably, the avoidance groove comprises a first avoidance groove for the slide pushing plate to enter and exit and a second avoidance groove for the slide reset pushing plate to enter and exit.
Further preferably, the widths of the first avoidance groove and the second avoidance groove are smaller than the width of the slide positioning groove.
Further preferably, the first avoidance groove and the second avoidance groove have a depth greater than that of the slide positioning groove.
Further preferably, the Z-axis fixed plate is respectively provided with a Z-axis position sensor in the limit movement direction of the X-axis movable plate; x-axis position sensors are respectively arranged on the X-axis movable plate in the limit movement direction of the Y-axis movable plate; and Y-axis position sensors are respectively arranged on the Y-axis movable plate in the limiting movement direction of the glass carrying table.
Further preferably, a light hole is provided in the slide positioning groove.
Further preferably, a pressing plate is arranged at the position of the slide positioning groove for inserting the slide, one end of the pressing plate is provided with a downward bulge to form pressing arrangement of the slide, and the end part of the other end of the pressing plate is upturned to form a guide plate for inserting the slide.
The invention has the beneficial effects that:
the invention relates to a high-precision microscopic scanning platform for automatically loading slides, which comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixed plate and a Z-axis lead screw nut mechanism arranged on the Z-axis fixed plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw nut mechanism in a sliding way; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is slidably assembled in the X-axis screw nut mechanism; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding way; the glass slide table is provided with a slide positioning groove for inserting a slide, the bottom of the slide positioning groove is provided with an avoidance groove, and the avoidance groove is communicated in the slide inserting direction.
The high-precision microscopic scanning platform for automatically loading the slide can quickly and automatically load the slide, the triaxial mechanism can quickly and accurately send the slide to a scanning position, the objective lens can be quickly switched at any time according to the type of the slide, the automation degree is high, the positioning is accurate, the speed is high, and the requirement of large-scale continuous scanning can be met.
Drawings
FIG. 1 is a schematic diagram of the structure of a high-precision microscanning platform for automatically loading slides according to the present invention;
FIG. 2 is a schematic view of the structure of FIG. 1 from another perspective;
FIG. 3 is a schematic view of the structure of the high-precision microscanning platform of the present invention for automatically loading slides;
FIG. 4 is a schematic view of the glass carrier in FIGS. 1-3;
FIG. 5 is a schematic view of the slide pusher plate mated with the glass carrier;
FIG. 6 is a schematic view of the structure of a high precision microscanning platform slide pusher plate of the present invention for automatically loading slides;
fig. 7 is a schematic of a portion of the structure of a high-precision microscanning platform microscope of the present invention automatically loaded with slides.
Name corresponding to each label in the figure:
1. A Z-axis mechanism, 11, a Z-axis screw nut mechanism, 12, a Z-axis fixing plate, 111, a first screw, 112, a first servo motor, 13, a base, 121, a Z-axis slide rail, 14, a Z-axis position sensor, 15, a Z-axis sensor sensing plate, 16, a Z-axis nut,
2. An X-axis mechanism, 21, an X-axis screw nut mechanism, 22, an X-axis movable plate, 23, an X-axis movable plate bracket, 211, a second screw rod, 212, a second servo motor, 221, an X-axis slide rail, 24, an X-axis position sensor, 25, an X-axis sensor sensing plate, 26, an X-axis nut,
3. A Y-axis mechanism, 31, a Y-axis screw nut mechanism, 32, a Y-axis movable plate, 311, a third screw, 312, a third servo motor, 321, a Y-axis slide rail, 33, a Y-axis position sensor, 34, a Y-axis sensor sensing plate, 35, a glass carrying table, 351, a slide positioning groove, 352, a positioning step surface, 353, a pressing plate, 354, a light transmitting hole, 355, a back plate, 356, a first avoiding groove, 357, a slide position sensor, 358, a second avoiding groove, 36, a Y-axis nut,
4. Slide pushing mechanism, 41, slide pushing plate, 42, slide reset pushing plate,
5. A microscope scanning mirror, 51, a switchable objective lens, 511, an objective lens gear ring, 52, an objective lens switching device, 521, an objective lens switching motor, 522, a motor fixing frame, 523, a motor gear,
6. The visual sense of the sensor is that,
7. A vertical frame, 71 and a clamping groove,
8. The dipping mirror oil is dripped into the pipe.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention.
Example 1 of the present invention:
as shown in fig. 1-6, the high precision microscope scanning platform for automatically loading slides comprises an X-axis mechanism 2, a Y-axis mechanism 3, a Z-axis mechanism 1, a microscope scanning mirror 5 and a slide pushing mechanism 4.
As shown in fig. 1 to 3, the Z-axis mechanism 1 includes a Z-axis screw nut mechanism 11 and a Z-axis fixing plate 12, the Z-axis screw nut mechanism 11 is provided on the Z-axis fixing plate 12, the Z-axis screw nut mechanism 11 includes a screw, denoted as a first screw 111, driving the screw is a first servo motor 112, the Z-axis fixing plate 12 is vertically mounted on the base 13, a Z-axis slide rail 121 is provided on the Z-axis fixing plate 12, and the Z-axis slide rail 121 is vertically provided.
The side of the Z-axis fixed plate 12 is provided with two Z-axis position sensors 14, the Z-axis position sensors 14 are respectively arranged at the limit positions of the X-axis movable plate 22 moving up and down along the Z axis, and the side of the X-axis movable plate 22 is provided with a Z-axis sensor sensing plate 15 matched with the Z-axis position sensors 14.
The X-axis mechanism 2 includes an X-axis screw nut mechanism 21 and an X-axis movable plate 22.
The X-axis movable plate 22 is horizontally arranged, an X-axis movable plate bracket 23 is arranged on the lower side of the X-axis movable plate 22, the X-axis movable plate 22 is arranged on the X-axis movable plate bracket 23, and the side surface of the X-axis movable plate bracket 23 is fixedly connected with a Z-axis nut 16 in the Z-axis screw nut mechanism 11.
The X-axis movable plate bracket 23 is further provided with a slider which is matched and slidingly connected with the Z-axis sliding rail 121, and the X-axis movable plate 22 is slidingly assembled on the Z-axis fixed plate 12 along the Z-axis.
The X-axis screw nut mechanism 21 is fixed to a side surface of the X-axis movable plate 22, and the X-axis screw nut mechanism 21 includes a screw, denoted as a second screw 211, and a second servo motor 212 drives the screw.
The X-axis movable plate 22 is provided with an X-axis slide rail 221, and the X-axis slide rail 221 is horizontally arranged.
As shown in fig. 2, two X-axis position sensors 24 are provided on the bottom surface of the X-axis movable plate 22, the X-axis position sensors 24 are respectively provided at the limit positions of the Y-axis movable plate 32 moving left and right along the X-axis, and an X-axis sensor sensing plate 25 cooperating with the X-axis position sensors 24 is provided on the X-axis nut 26.
The Y-axis mechanism 3 includes a Y-axis movable plate 32 and a Y-axis lead screw nut mechanism 31 mounted on the Y-axis movable plate.
The Y-axis movable plate 32 is provided with a slider which is matched with the X-axis slide rail 221, the Y-axis movable plate 32 is slidably assembled on the X-axis movable plate 22, and the Y-axis movable plate 32 horizontally moves along the X-axis slide rail 221.
The Y-axis screw nut mechanism 31 is fixed to the upper side surface of the Y-axis movable plate 32, and includes a screw, denoted as a third screw 311, and a third servo motor 312 for driving the screw.
The Y-axis movable plate 32 is provided with a Y-axis slide rail 321, and the Y-axis slide rail 321 is horizontally arranged.
The side of the Y-axis movable plate 32 extends out of a screw fixing seat, namely an X-axis nut 26 in the X-axis screw nut mechanism 21. The Y-axis movable plate 32 is driven by the X-axis screw nut mechanism 21 to slide on the X-axis movable plate 22.
The glass carrying platform 35 is arranged on the Y-axis movable plate 32, a sliding block matched with the Y-axis sliding rail 321 is arranged on the glass carrying platform 35, the glass carrying platform 35 is slidingly assembled on the Y-axis movable plate 32, and the glass carrying platform 35 horizontally moves along the Y-axis sliding rail 321.
The glass carrying table 35 is fixed on a Y-axis nut 36 in the Y-axis screw nut mechanism 31, and the Y-axis screw nut mechanism 31 drives the glass carrying table 35 to horizontally move along the front-back direction of the Y-axis slide rail 321.
Two Y-axis position sensors 33 are arranged on the upper side surface of the Y-axis movable plate 32, the Y-axis position sensors 33 are respectively arranged at the limit positions of the glass carrying table 35 moving back and forth along the Y axis, and a Y-axis sensor sensing plate 34 matched with the Y-axis position sensors 33 is arranged on a Y-axis nut 36.
As shown in fig. 3, a slide positioning groove 351 is provided on the glass stage 35, and a positioning step surface 352 is provided in the slide positioning groove 351, the positioning step surface 352 being used for positioning the slide.
As shown in fig. 4, the four corners of the slide positioning groove are provided with pressing plates 353, one end of each pressing plate 353 is provided with a downward bulge for pressing a slide to enable the slide to be more stably placed in the slide positioning groove 351, the other end of each pressing plate 353 is close to the position where the slide is inserted, the end of each pressing plate 353 is tilted upwards to form a guide plate for inserting the slide, and the slide cannot be pushed into the slide positioning groove due to small errors, so that the slide is prevented from being damaged.
As shown in fig. 4, a light hole 354 is formed at the bottom of the slide positioning groove 351, and corresponds to the sample position of the slide, so that the scanning by a microscope is facilitated.
In order to ensure that the slide pushing plate 41 and the slide reset pushing plate 42 can smoothly enter and exit the slide positioning groove 351, the following design is made, a first avoidance groove 356 and a second avoidance groove 358 are formed in the bottom of the slide positioning groove 351, the first avoidance groove 356 and the second avoidance groove 358 are communicated with each other in the slide positioning groove 351 along the slide entering and exiting direction, the first avoidance groove 356 is used for allowing the slide pushing plate 41 to enter and exit the slide positioning groove 351, the second avoidance groove 358 is used for allowing the slide reset pushing plate 42 to enter and exit the slide positioning groove 351, and the widths of the first avoidance groove 356 and the second avoidance groove 358 are the same and smaller than the width of the slide positioning groove 351. The depth of the first avoiding groove 356 is equal to the thickness of the slide pushing plate 41, and the depth of the second avoiding groove 358 is equal to the thickness of the slide reset pushing plate 42, so that the slide pushing plate 41 and the slide reset pushing plate 42 can conveniently enter and exit the slide positioning groove 351. The slide pushing plate 41 pushes the slide into the slide positioning groove 351 quickly, and the slide reset pusher 42 pushes the slide out of the slide positioning groove 351 quickly after the scanning is completed.
The slide enters the slide positioning slot 351 and the recovery after the scan is completed by the slide pushing mechanism 4.
As shown in fig. 5-6, the slide pushing mechanism 4 is of a T-shaped plate structure, the slide pushing mechanism 4 comprises a slide pushing plate 41 and a slide reset pushing plate 42, the slide pushing plate 41 is arranged at one end of the T-shaped plate, the slide reset pushing plate 42 is arranged at the other end of the T-shaped plate, the slide pushing plate 41 is of a strip-shaped plate and used for pushing a slide in a slide box into a slide positioning groove 351, the slide reset pushing plate 42 is used for pushing the slide back into the slide box from the slide positioning groove 351, the slide pushing plate and the slide reset pushing plate have the same width and are horizontally arranged at the same height, and the slide pushing mechanism 4 is driven by a screw-nut mechanism.
As shown in fig. 3, a visual sensor 6 is disposed above a slide positioning groove 351, the visual sensor 6 is mounted on a stand 7, a clamping groove 71 is disposed on the stand 7, the visual sensor is disposed in the clamping groove 71, the visual sensor can move a certain distance in the clamping groove 71, and the position of the visual sensor 6 can be adjusted according to different slide samples, so that the visual recognition of the visual sensor 6 is ensured to be more accurate. The vision sensor 6 photographs the slide in the slide positioning groove 351, recognizes the position of the sample on the slide, feeds back to the control system, and the control system controls the X-axis mechanism 2, the Y-axis mechanism 3 and the Z-axis mechanism 1to adjust the position of the slide, so that the sample is in a proper range of scanning, and the accuracy of the scanning result is improved.
The left side of the vision sensor 6 is provided with a dipping mirror oil drop adding pipe 8, the dipping mirror oil drop adding pipe 8 is arranged on the vertical frame, and the dipping mirror oil drop adding pipe 8 is used for dropping dipping mirror oil on a slide in the slide positioning groove 351.
The backplate 355 is provided with to slide constant head tank 351's below, as shown, and backplate 355 is used for providing image acquisition's background for vision sensor 6, makes the image more clear, can receive sample and the immersion oil that flow out on the slide simultaneously, guarantees the inside cleanness of microscan.
As shown in fig. 7, a micro-scanning mirror 5 is provided above the glass stage 35, and the micro-scanning mirror 5 includes a switchable objective lens 51 and an objective lens switching device 52.
The circumference is provided with objective ring gear 511 on the objective lens frame, the objective lens frame can rotate and be used for switching different objective lenses, objective lens conversion device 52 sets up on the microscope support, objective lens conversion device 52 includes objective lens conversion motor 521 and motor fixed frame 522, motor fixed frame 522 installs on the microscope support, objective lens conversion motor 521 sets up in motor fixed frame 522, install motor gear 523 in the objective lens conversion motor 521 pivot, motor gear 523 and objective lens ring gear 511 meshing rotate and are connected, objective lens conversion motor 521's rotation drives the rotatory change objective lens of objective lens, can scan different grade type slide sample, motor gear 523 and objective lens ring gear 511 cooperation transmission, and is efficient, position adjustment is accurate, can accomplish objective lens switching work fast and stably.
The working principle of the high-precision microscopic scanning platform for automatically loading the glass slide is as follows:
After the slide is pushed by the slide pushing plate 41 in the slide pushing mechanism 4 and enters the slide positioning groove 351, the slide position sensor 357 judges that the slide enters the slide positioning groove 351, the vision sensor 6 photographs the slide, judges the position of a sample on the slide, feeds back slide position information to the scanning platform, the X-axis mechanism 2, the Y-axis mechanism 3 and the Z-axis mechanism 1 start to work, wherein the Z-axis mechanism 1 firstly moves downwards for a certain distance to avoid interference of the slide pushing plate 41 on the glass table 35, then the X-axis mechanism 2 and the Y-axis mechanism 3 act to accurately send the slide to the position under the objective lens of the microscope, and if different objective lenses need to be switched, the objective lens switching motor 521 acts to drive the objective lens frame to rotate and adjust different objective lenses. After the scanning is completed, the X-axis mechanism 2, the Y-axis mechanism 3 and the Z-axis mechanism 1 are reset, the slide positioning groove 351 returns to the initial position, and at the moment, the slide reset push plate 42 in the slide pushing mechanism 4 pushes out the slide in the slide positioning groove 351 to return to the slide box, so that the automatic scanning of the slide is completed.
The high-precision microscopic scanning platform for automatically loading the glass slide has the characteristics of compact structure, high transmission efficiency and low failure rate, compared with the existing mechanical arm structure, the glass slide pushing mechanism can complete two processes of conveying the glass slide to the glass carrier and conveying the glass slide back to the glass carrier box only by reciprocating in one direction of a horizontal plane, the efficiency is greatly improved, the three-axis platform of the glass carrier has more degrees of freedom, the glass carrier is suitable for various glass slide scanning requirements, the objective lens can be rapidly switched, and the glass slide scanning efficiency is improved.
Claims (5)
1. A high-precision microscopic scanning platform for automatically loading a slide, which is characterized in that: comprises a Z-axis mechanism, an X-axis mechanism and a Y-axis mechanism; the Z-axis mechanism comprises a Z-axis fixing plate and a Z-axis lead screw nut mechanism arranged on the Z-axis fixing plate; the X-axis mechanism comprises an X-axis movable plate and an X-axis screw nut mechanism arranged on the X-axis movable plate, and the X-axis movable plate is assembled on the Z-axis screw nut mechanism in a sliding way; the Y-axis mechanism comprises a glass carrying table, a Y-axis movable plate and a Y-axis screw nut mechanism arranged on the Y-axis movable plate, and the Y-axis movable plate is slidably assembled in the X-axis screw nut mechanism; the glass carrying table is assembled in the Y-axis screw nut mechanism in a sliding way; the glass slide table is provided with a slide positioning groove for inserting a slide, the bottom of the slide positioning groove is provided with an avoidance groove, and the avoidance groove is communicated in the slide inserting direction; the slide positioning groove is provided with a pressing plate at the position for inserting the slide, one end of the pressing plate is provided with a downward bulge to form pressing arrangement on the slide, and the other end of the pressing plate is upturned to form a guide plate for inserting the slide; a slide position sensor is arranged in the slide positioning groove; the slide positioning groove is provided with a pushing mechanism at one side for inserting the slide, and the pushing mechanism comprises a slide pushing plate for pushing the slide into the slide positioning groove from the slide box, a slide reset pushing plate for pushing the slide back into the slide box from the slide positioning groove, and a pushing mechanism supporting plate, wherein the slide pushing plate and the slide reset pushing plate are respectively arranged at two ends of the pushing mechanism supporting plate; the slide pushing plate and the slide reset pushing plate are horizontally arranged at the same height; the avoidance groove comprises a first avoidance groove for the slide pushing plate to enter and exit and a second avoidance groove for the slide reset pushing plate to enter and exit; a visual sensor is arranged above the slide positioning groove, the visual sensor is arranged on the vertical frame, a clamping groove is arranged on the vertical frame, the visual sensor is arranged in the clamping groove, the visual sensor is used for photographing a slide in the slide positioning groove so as to identify the position of a sample on the slide, the sample is fed back to a control system, and the control system controls an X-axis mechanism, a Y-axis mechanism and a Z-axis mechanism to adjust the position of the slide so as to accurately push the slide under an objective lens of a microscope; the left side of the vision sensor is provided with a dipping mirror oil drop adding pipe, the dipping mirror oil drop adding pipe is arranged on the vertical frame and used for dripping the dipping mirror oil drop on a slide in the slide positioning groove, a backboard is arranged below the slide positioning groove and used for providing an image acquisition background for the vision sensor and receiving a sample flowing out of the slide and the dipping mirror oil.
2. A high precision microscanning platform for automatically loading slides according to claim 1, wherein: the width of the first avoidance groove and the width of the second avoidance groove are smaller than the width of the slide positioning groove.
3. A high precision microscanning platform for automatically loading slides according to claim 2, wherein: the depth of the first avoidance groove and the second avoidance groove is greater than that of the slide positioning groove.
4. A high precision microscanning platform for automatically loading slides according to claim 1, wherein: z-axis position sensors are respectively arranged on the Z-axis fixed plate in the limit movement direction of the X-axis movable plate; x-axis position sensors are respectively arranged on the X-axis movable plate in the limit movement direction of the Y-axis movable plate; and Y-axis position sensors are respectively arranged on the Y-axis movable plate in the limiting movement direction of the glass carrying table.
5. A high precision microscanning platform for automatically loading slides according to claim 1, wherein: and a light hole is arranged in the slide positioning groove.
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| CN202110171475.7A CN112945957B (en) | 2021-02-08 | 2021-02-08 | High-precision microscopic scanning platform capable of automatically loading slide |
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| CN202110171475.7A CN112945957B (en) | 2021-02-08 | 2021-02-08 | High-precision microscopic scanning platform capable of automatically loading slide |
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| CN112945957B true CN112945957B (en) | 2024-05-14 |
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| CN113534431A (en) * | 2021-06-16 | 2021-10-22 | 武汉希诺智能医学有限公司 | Two-dimensional two-section type precise movement platform of microscope |
| CN114324167B (en) * | 2021-12-31 | 2024-04-09 | 杭州千麦医学检验实验室有限公司 | Chromosome karyotype AI analysis detector |
| CN115015116A (en) * | 2022-05-31 | 2022-09-06 | 苏州秉理科技有限公司 | A carrier-type automatic digital slice scanning system |
| CN116202964A (en) * | 2023-03-03 | 2023-06-02 | 上海申挚医疗科技有限公司 | Slide detection device on stage, scanner and scanning method |
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