CN112925092B - Electronic hysteroscope imaging lens for gas and liquid uterus expansion - Google Patents
Electronic hysteroscope imaging lens for gas and liquid uterus expansion Download PDFInfo
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- G—PHYSICS
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- G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
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- A61B1/303—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the vagina, i.e. vaginoscopes
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Abstract
本发明公开了一种气体、液体膨宫两用的电子宫腔镜成像镜头,包括自物至像依次排列的第一透镜、第二透镜、第三透镜、第四透镜、第五透镜和第六透镜,第二透镜与第三透镜之间放置光阑,第四透镜与第五透镜组成双胶合透镜,第六透镜外侧放置像面。本发明镜头口径小,能够明显减轻患者痛苦,适于子宫癌早期诊断;结构简单,操作便捷,仅需调整透镜组间隔即可实现多场景应用需求;可实现90°视场无盲区、大景深、高分辨率成像,提高早期疾病尤其肿瘤的检出率及确诊率,减少医生对体内仪器不必要的操作,降低手术风险。
The invention discloses an electronic hysteroscope imaging lens for gas and liquid dilatation of the uterus. Six lenses, a diaphragm is placed between the second lens and the third lens, the fourth lens and the fifth lens form a doublet, and the image plane is placed outside the sixth lens. The lens of the invention has a small aperture, can obviously relieve the pain of patients, and is suitable for the early diagnosis of uterine cancer; the structure is simple, the operation is convenient, and multi-scene application requirements can be achieved only by adjusting the interval of the lens groups; it can realize a 90° field of view without blind spots and a large depth of field , High-resolution imaging, improve the detection rate and diagnosis rate of early diseases, especially tumors, reduce unnecessary operations by doctors on internal instruments, and reduce the risk of surgery.
Description
技术领域technical field
本发明涉及光学技术领域,具体涉及一种气体、液体膨宫两用的电子宫腔镜成像镜头,用于妇科微创手术及宫腔镜免麻醉检查时宫腔成像。The invention relates to the field of optical technology, in particular to an electronic hysteroscope imaging lens for gas and liquid dilatation of the uterus, which is used for uterine cavity imaging in gynecological minimally invasive surgery and hysteroscope-free anesthesia inspection.
背景技术Background technique
随着生活水平逐渐提高,人们越来越关注自身的健康。全球妇女恶性肿瘤中,宫颈癌发病率位居第二。宫颈细胞变异到癌细胞要历经十多年漫长的癌变周期,如果能在病变初期及时发现并医治,治愈率可达100%。目前在临床医学中,子宫疾病诊断方法主要有超声技术和医用内窥镜,传统超声技术只能观察到器官断层结构剖面,具有图像不直接、视野小等缺点;而内窥镜在医学领域应用已有近百年的历史,从1806年德国人发明了硬式内窥镜开始,经历了硬管式内窥镜、光纤内窥镜、电子内窥镜的发展进程,其中硬管式内窥镜照度低、观测角度受限、图像分辨率低以及检查时会给患者带来痛苦,限制了其在宫腔癌症早期诊断方面的应用;电子内窥镜是医生视觉的延伸,宫腔镜检查时应用超微细光纤把微小“电子眼”由阴道、子宫颈进入宫腔内,可在无需开腔或微创情况下由内窥镜直接呈现内脏器官表面的组织形态及体内病变情况,辅助医生进行宫腔疾病诊断与治疗,可明显减轻患者的痛苦程度,如子宫癌早期诊断以及子宫畸形、子宫内膜息肉、宫腔异物、异常子宫出血等疾病的诊疗,但现有技术的电子内窥镜仍存在以下缺点:With the gradual improvement of living standards, people pay more and more attention to their own health. Cervical cancer is the second most common cancer among women in the world. It takes more than ten years for cervical cells to mutate into cancer cells. If the disease can be detected and treated in time at the early stage, the cure rate can reach 100%. At present, in clinical medicine, the diagnosis methods of uterine diseases mainly include ultrasound technology and medical endoscope. Traditional ultrasound technology can only observe the cross-sectional structure of the organ, which has the disadvantages of not direct image and small field of view. However, endoscopy is used in the medical field. It has a history of nearly a hundred years. Since the invention of the rigid endoscope by the Germans in 1806, it has experienced the development process of the rigid endoscope, the fiber optic endoscope and the electronic endoscope. Low, limited observation angle, low image resolution, and pain to patients during inspection, limit its application in the early diagnosis of uterine cancer; electronic endoscope is an extension of the doctor's vision, and is used in hysteroscopy The ultra-fine optical fiber brings tiny "electronic eyes" from the vagina and cervix into the uterine cavity, which can directly display the tissue morphology of the surface of internal organs and the lesions in the body through the endoscope without opening the cavity or minimally invasive, assisting doctors in uterine cavity diseases. Diagnosis and treatment can significantly reduce the suffering of patients, such as the early diagnosis of uterine cancer and the diagnosis and treatment of uterine malformations, endometrial polyps, uterine foreign bodies, abnormal uterine bleeding and other diseases, but the electronic endoscopes in the existing technology still have the following: shortcoming:
(1)我国宫腔临床上普遍使用的硬管式内窥镜检测存在盲区、图像分辨率低、检查时会给患者带来痛苦,光纤内窥镜中玻璃纤维易断裂导致成像出现黑点,而传统B超技术除图像分辨率低之外还有图像不直接的问题,这些弊端都限制了它们在临床上的广泛使用。(1) The hard tube endoscope commonly used in clinical uterine cavity detection in China has blind spots, low image resolution, and pain to the patient during inspection. The glass fiber in the fiber optic endoscope is easy to break, resulting in black spots on the imaging. In addition to low image resolution, traditional B-ultrasound technology also has the problem of indirect images, which limit their widespread clinical use.
(2)因免麻醉电子宫腔镜价格昂贵很多依赖进口,增加了医院的医疗成本及资金投入,很多国产宫腔镜成像镜头硬质部外径均超出无麻醉宫腔诊断所容许8mm上限,诊断时需做麻醉,只适宜手术情况,不适宜单纯做子宫癌早期诊断,限制了其应用范围。(2) Due to the high price of anesthesia-free electronic hysteroscopes, many rely on imports, which increases the medical cost and capital investment of hospitals. The outer diameter of the hard part of many domestic hysteroscopic imaging lenses exceeds the upper limit of 8mm allowed for the diagnosis of uterine cavity without anesthesia. Anesthesia is required for diagnosis, and it is only suitable for surgical conditions, not for early diagnosis of uterine cancer, which limits its application range.
(3)为清晰观察宫腔构造,检查时需对宫腔进行膨宫,针对不同的膨宫方式如气体膨宫与液体膨宫需选用不同的宫腔镜成像镜头,增加了医院的资金投入;由于加工装配宫腔镜头时是在空气中,对生产加工阶段实时检测液体膨宫状态时宫腔镜像质存在一定困难。(3) In order to clearly observe the structure of the uterine cavity, the uterine cavity needs to be distended during the examination. Different hysteroscopic imaging lenses should be used for different methods of uterine distention, such as gas and liquid uterine distention, which increases the hospital’s capital investment. ; Since the uterine lens is in the air when processing and assembling, it is difficult to detect the quality of the uterine mirror in real time during the production and processing stage when the state of liquid distended uterus is detected.
发明内容SUMMARY OF THE INVENTION
本发明所要解决的技术问题是针对上述背景技术的不足,提供一种适用于气体膨宫或液体膨宫两种膨宫状态的免麻醉、大景深、无盲区的电子宫腔镜成像镜头。The technical problem to be solved by the present invention is to provide an anesthesia-free, large depth of field, and no blind spot electronic hysteroscope imaging lens suitable for gas or liquid uterine distention.
为实现上述发明目的,本发明采用以下技术方案:In order to realize the above-mentioned purpose of the invention, the present invention adopts the following technical solutions:
一种气体、液体膨宫两用的电子宫腔镜成像镜头,包括自物至像依次排列的第一透镜、第二透镜、第三透镜、第四透镜、第五透镜和第六透镜,第二透镜与第三透镜之间放置光阑,第四透镜与第五透镜组成双胶合透镜,第六透镜外侧放置像面。An electronic hysteroscope imaging lens for gas and liquid dilatation of the uterus, comprising a first lens, a second lens, a third lens, a fourth lens, a fifth lens and a sixth lens arranged in sequence from the object to the image. A diaphragm is placed between the second lens and the third lens, the fourth lens and the fifth lens form a doublet, and the image plane is placed outside the sixth lens.
所述第一透镜前后表面的曲率半径均为正值,前表面为低阶非球面,后表面为高阶非球面。The curvature radii of the front and rear surfaces of the first lens are all positive values, the front surface is a low-order aspheric surface, and the rear surface is a high-order aspheric surface.
所述第二透镜前后表面的曲率半径均为正值,前表面为高阶非球面,后表面为低阶非球面。The curvature radii of the front and rear surfaces of the second lens are all positive values, the front surface is a high-order aspheric surface, and the rear surface is a low-order aspheric surface.
所述第三透镜前表面的曲率半径为正值,后表面的曲率半径为负值,前表面为高阶非球面,后表面为低阶非球面。The curvature radius of the front surface of the third lens is a positive value, the curvature radius of the rear surface is a negative value, the front surface is a high-order aspheric surface, and the rear surface is a low-order aspheric surface.
所述第四透镜前后表面的曲率半径均为正值,前表面为低阶非球面,后表面为标准球面。The curvature radii of the front and rear surfaces of the fourth lens are all positive values, the front surface is a low-order aspheric surface, and the rear surface is a standard spherical surface.
所述第五透镜前表面的曲率半径为正值,后表面的曲率半径为负值,前表面为标准球面,后表面为高阶非球面。The curvature radius of the front surface of the fifth lens is a positive value, the curvature radius of the rear surface is a negative value, the front surface is a standard spherical surface, and the rear surface is a high-order aspherical surface.
所述第六透镜前后表面的曲率半径均为负值,前表面为低阶非球面,后表面为高阶非球面。所述第一透镜和第二透镜组成的光具组光焦度为负值。The curvature radii of the front and rear surfaces of the sixth lens are all negative values, the front surface is a low-order aspheric surface, and the rear surface is a high-order aspheric surface. The optical power of the optical train composed of the first lens and the second lens is a negative value.
所述第三透镜、第四透镜、第五透镜与第六透镜组成的光具组光焦度为正值。The optical power group composed of the third lens, the fourth lens, the fifth lens and the sixth lens is a positive value.
与现有技术相比,本发明具有以下有益效果:Compared with the prior art, the present invention has the following beneficial effects:
(1)电子宫腔镜成像镜头的口径限制在3.2mm以内,满足无麻醉宫腔病变诊断需求,能够明显减轻检查时患者痛苦,适于子宫癌早期诊断;(1) The diameter of the imaging lens of the electronic hysteroscope is limited to within 3.2mm, which meets the needs for the diagnosis of intrauterine lesions without anesthesia, can significantly reduce the pain of patients during examination, and is suitable for the early diagnosis of uterine cancer;
(2)仅需调整透镜组间隔即可实现不同的应用需求,如气体膨宫与液体膨宫时的宫腔镜检查;生产装配阶段检测空气介质宫腔镜像质的同时,也为实际诊疗阶段液体膨宫状态时宫腔镜成像系统像质检测提供了重要依据;(2) Different application requirements can be achieved only by adjusting the interval of the lens groups, such as hysteroscopy in gas and liquid dilatation; in the production and assembly stage, the quality of the air-medium uterine mirror is detected, and it is also in the actual diagnosis and treatment stage. The quality detection of hysteroscopic imaging system provides an important basis for the detection of fluid distended uterus;
(3)可实现90°视场无盲区、大景深高分辨率成像,既可观测全视场图像,又可获取病灶区域的细节,实现局部范围内病灶的低畸变高清晰图像放大,像质优良,提高早期疾病尤其肿瘤的检出率及确诊率,无盲区的成像特性可使宫腔镜处在某一固定位置进行全视场观测,减少医生对体内仪器不必要的操作,降低手术风险。(3) It can realize high-resolution imaging with 90° field of view without blind area and large depth of field, which can not only observe the full field of view image, but also obtain the details of the lesion area, and realize the low-distortion and high-definition image enlargement of the lesion in the local area. Excellent, improve the detection rate and diagnosis rate of early-stage diseases, especially tumors, and the imaging characteristics of no blind spot allow the hysteroscope to be in a fixed position for full-field observation, reducing unnecessary operations by doctors on internal instruments and reducing surgical risks. .
附图说明Description of drawings
图1为电子宫腔镜成像镜头结构示意图(物距100mm);Figure 1 is a schematic diagram of the structure of an electronic hysteroscope imaging lens (object distance 100mm);
图2为液体膨宫状态的电子宫腔镜成像系统RayFan曲线及场曲、畸变图像(物距100mm),其中图2(2a)为RayFan曲线,图2(2b)为场曲、畸变图像;Figure 2 is the RayFan curve and the field curvature and distortion images of the electronic hysteroscopy imaging system in the state of liquid distended uterus (object distance 100mm), of which Figure 2(2a) is the RayFan curve, and Figure 2(2b) is the field curvature and distortion images;
图3为气体膨宫状态的电子宫腔镜成像系统RayFan曲线及场曲、畸变图像(物距100mm),其中图3(3a)为RayFan曲线,图3(3b)为场曲、畸变图像;Figure 3 is the RayFan curve and the field curvature and distortion images of the electronic hysteroscopy imaging system in the state of gas distended uterus (object distance 100mm), of which Figure 3(3a) is the RayFan curve, and Figure 3(3b) is the field curvature and distortion images;
图4为电子宫腔镜成像系统相对照度图(物距100mm),其中图4(4a)为液体膨宫状态,图4(4b)为气体膨宫状态;Figure 4 is the relative illumination diagram of the electronic hysteroscopy imaging system (object distance 100mm), in which Figure 4 (4a) is the state of liquid distended uterus, and Figure 4 (4b) is the state of gas distended uterus;
图5-7分别为物距80mm、100mm和120mm时气体膨宫状态的电子宫腔镜成像系统传函曲线与点列图,其中图5(5a)、图6(6a)、图7(7a)为传函曲线,图5(5b)、图6(6b)、图7(7b)为点列图;Figures 5-7 are the transfer function curves and point diagrams of the electronic hysteroscopy imaging system of the gas distended uterus when the object distances are 80mm, 100mm and 120mm, respectively. Figures 5(5a), 6(6a) and 7(7a) ) is the transfer curve, and Figure 5(5b), Figure 6(6b), and Figure 7(7b) are point diagrams;
图8-10分别为物距80mm、100mm和120mm时液体膨宫状态的电子宫腔镜成像系统传函曲线与点列图,其中图8(8a)、图9(9a)、图10(10a)为传函曲线,图8(8b)、图9(9b)、图10(10b)为点列图。Figures 8-10 are the transfer function curves and point diagrams of the electronic hysteroscopy imaging system for the liquid uterine distended state when the object distances are 80mm, 100mm and 120mm, respectively. Figures 8(8a), 9(9a) and 10(10a) ) is the transfer curve, and Figure 8 (8b), Figure 9 (9b), and Figure 10 (10b) are point diagrams.
具体实施方式Detailed ways
下面结合附图对本发明的技术方案作进一步说明。The technical solutions of the present invention will be further described below with reference to the accompanying drawings.
本发明所述的电子宫腔镜成像镜头选用五片式负光焦度在前正光焦度在后的“反远距型”透镜组做初始结构,可以兼顾大视场角及大相对孔径,有较长的后工作距,与双高斯结构相比,像面照度比较均匀。The electronic hysteroscope imaging lens of the present invention selects a five-piece negative focal power in the front and a "reverse telephoto" lens group with a positive focal power in the back as the initial structure, which can take into account a large field of view and a large relative aperture. Compared with the double Gaussian structure, the image surface illumination is relatively uniform.
如图1所示,本发明所述的电子宫腔镜成像镜头包括自物至像依次排列的第一透镜1、第二透镜2、第三透镜4、第四透镜5、第五透镜6与第六透镜7,第二透镜2与第三透镜4之间放置光阑 3,第四透镜5与第五透镜6组成双胶合透镜,第六透镜7以后放置像面8。其中第一透镜1前后表面的曲率半径均为正值,前表面为低阶非球面,后表面为高阶非球面,第二透镜2前后表面的曲率半径均为正值,前表面为高阶非球面,后表面为低阶非球面,第三透镜4前表面的曲率半径为正值,后表面的曲率半径为负值,前表面为高阶非球面,后表面为低阶非球面,第四透镜5前后表面的曲率半径均为正值,前表面为低阶非球面,后表面为标准球面,第五透镜6前表面的曲率半径为正值,后表面的曲率半径为负值,前表面为标准球面,后表面为高阶非球面,第六透镜7前后表面的曲率半径均为负值,前表面为低阶非球面,后表面为高阶非球面。第一透镜1和第二透镜2组成的光具组光焦度为负值;第三透镜4、第四透镜5、第五透镜6与第六透镜7组成的光具组光焦度为正值。As shown in FIG. 1, the electronic hysteroscope imaging lens of the present invention includes a
为提高对目标观察的精细程度,要求内窥镜具有大景深和高分辨率。若分辨率不佳,体内组织特性和病灶区域细节无法获取,失去临床诊断的意义;若景深过小,则成像清晰范围不足,视场模糊易造成误诊;由仪器分辨率公式可知,入瞳直径越大,分辨率越高,景深越小;为提高系统分辨率,单纯以提高入瞳直径的方法易导致像质下降,且入瞳直径越大景深越小,所以入瞳直径不可以无限制增大,优选地,将系统入瞳直径增加至D=0.35mm,设计时需将物距设置为多重结构进行优化,兼顾系统工作距离对景深的影响,优选地,将景深范围控制在80~120mm之间。In order to improve the fineness of the target observation, the endoscope is required to have a large depth of field and high resolution. If the resolution is poor, the characteristics of the tissue in the body and the details of the lesion area cannot be obtained, and the significance of clinical diagnosis will be lost; if the depth of field is too small, the clear range of imaging will be insufficient, and the blurred field of view will easily lead to misdiagnosis. The larger the resolution, the smaller the depth of field; in order to improve the system resolution, simply increasing the diameter of the entrance pupil will easily lead to image quality degradation, and the larger the diameter of the entrance pupil, the smaller the depth of field, so the diameter of the entrance pupil cannot be unlimited. Increase, preferably, the diameter of the entrance pupil of the system is increased to D=0.35mm, and the object distance needs to be set to multiple structures for optimization during design, taking into account the influence of the system working distance on the depth of field, preferably, the depth of field range is controlled at 80~ between 120mm.
为在有限口径下获得更大观察范围,优选地,将视场角定为90°。若成像存在严重的大视场像差如畸变、场曲及像散,畸变会影响医生准确判断病变位置,场曲或像散将导致医生观测视野不够清晰易造成误诊,优化时需对像质较差的视场及时调整权重,将场曲、像散控制在公差允许范围内;低畸变无盲区的成像特性可使宫腔镜处在某一固定位置进行全视场观测,减少医生对体内仪器不必要的操作,精准判断病变位置,从而降低手术风险,对于提高工作效率、增加获取的图像信息量有重要意义。In order to obtain a larger observation range under a limited aperture, preferably, the field of view angle is set to 90°. If the imaging has serious large field of view aberrations such as distortion, field curvature and astigmatism, the distortion will affect the doctor's accurate judgment of the lesion location. The field curvature or astigmatism will cause the doctor's observation field to be unclear and easily lead to misdiagnosis. The weight of the poor field of view is adjusted in time to control the field curvature and astigmatism within the allowable tolerance range; the imaging characteristics of low distortion and no blind spot allow the hysteroscope to be in a fixed position for full field of view observation, reducing the doctor's attention to the body. The unnecessary operation of the instrument can accurately determine the location of the lesion, thereby reducing the risk of surgery, which is of great significance for improving work efficiency and increasing the amount of acquired image information.
同时,引入非球面可简化结构降低光能损耗,提高像质及像面照度,还可实现镜头组小型化将镜头组外径控制在3.2mm以内,适应无麻醉宫腔检查的需求。但非球面的使用会增加元件制造及检测成本,需严格控制该宫腔镜非球面数量,考虑到液体膨宫状态下使用时系统封装要求,尽量避免在第一面使用高阶非球面。At the same time, the introduction of aspheric surface can simplify the structure, reduce light energy loss, improve image quality and image surface illumination, and also realize the miniaturization of the lens group and control the outer diameter of the lens group within 3.2mm, which is suitable for the needs of anesthesia-free uterine cavity examination. However, the use of aspheric surfaces will increase the cost of component manufacturing and testing. It is necessary to strictly control the number of aspheric surfaces of the hysteroscope. Considering the system packaging requirements when using the hysteroscope in a liquid distended state, try to avoid using high-order aspheric surfaces on the first side.
由于该宫腔镜需工作在气体膨宫与液体膨宫两种工作状态,需将物面与透镜第一面间的玻璃材质设置为多重结构进行优化,这种设计方案也大大方便了生产加工阶段及成像镜头封装以后液体膨宫状态宫腔镜像质检测。Since the hysteroscope needs to work in two working states of gas distention and liquid distention, the glass material between the object surface and the first surface of the lens needs to be set to multiple structures for optimization. This design scheme also greatly facilitates production and processing. Mirror quality detection of uterine cavity in the state of liquid distended uterus after encapsulation of stage and imaging lens.
如表1和表2所示,考虑到系统封装要求,避免了透镜组第一面使用高阶非球面,因气体膨宫与液体膨宫透镜结构参数相同,只需调整各透镜组间隔即可应用在气体膨宫与液体膨宫两种不同的工作状态,节约了成本,在生产装配阶段检测空气介质宫腔镜像质的同时,也为液体膨宫状态时宫腔镜成像系统像质检测提供了重要依据。As shown in Table 1 and Table 2, considering the system packaging requirements, the use of a high-order aspheric surface on the first surface of the lens group is avoided. Since the structural parameters of the gas dilatation lens and the liquid dilatation lens are the same, it is only necessary to adjust the interval of each lens group. It is used in two different working states of gas distention and liquid distention, which saves costs. It can detect the mirror quality of the air medium uterus in the production and assembly stage, and also provide the image quality detection of the hysteroscopic imaging system in the state of liquid distention. important basis.
表1电子宫腔镜成像镜头LensDataEditorTable 1 Electronic hysteroscopy imaging lens LensDataEditor
表2电子宫腔镜成像镜头多重结构数据Table 2 Multiple structural data of the imaging lens of electronic hysteroscopy
本发明所述的电子宫腔镜成像镜头最大视场角为90°,工作景深为80~120mm,优选地,成像镜头口径在3.2mm以内,成像系统第一面到像面的距离在6.5mm以内,可以实现免麻醉、无盲区、大景深宫腔诊断的需求。The electronic hysteroscope imaging lens of the present invention has a maximum field of view angle of 90° and a working depth of field of 80-120 mm. Preferably, the diameter of the imaging lens is within 3.2 mm, and the distance from the first surface of the imaging system to the image surface is 6.5 mm. Within the scope, it can meet the needs of no anesthesia, no blind spot, and large depth of field diagnosis of the uterine cavity.
本发明所述的电子宫腔镜成像镜头空间分辨率及视场角均满足1/6英寸CCD的要求,优选地, 1/6英寸CCD具体参数为2.4mm×1.8mm,对角线3mm,如表1所示,电子宫腔镜所成的像在像面 8的最大直径为2.999mm,当1/6英寸CCD图像传感器置于光学系统像面8,所成的像应外接1/6 英寸CCD。如图5-10所示,在气体膨宫与液体膨宫两种工作状态,光学系统空间分辨率100lp/mm 处光学调制传递函数MTF>0.4,满足1/6英寸CCD空间分辨率的要求,气体膨宫与液体膨宫两种工作状态全视场点列图RMS半径以及GEO半径均小于系统衍射艾里斑半径,可以实现高清晰成像。The spatial resolution and field of view of the electronic hysteroscope imaging lens of the present invention both meet the requirements of a 1/6-inch CCD. As shown in Table 1, the maximum diameter of the image formed by the electronic hysteroscope on the
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