CN112915013B

CN112915013B - Integrated dispensing injector and using method thereof

Info

Publication number: CN112915013B
Application number: CN202110214336.8A
Authority: CN
Inventors: 俞志平
Original assignee: Meilan Hangzhou Pharmaceutical Technology Co ltd
Current assignee: Meilan Hangzhou Pharmaceutical Technology Co ltd
Priority date: 2020-09-10
Filing date: 2021-02-26
Publication date: 2022-01-04
Anticipated expiration: 2041-02-26
Also published as: CN215875548U; CN112915013A

Abstract

The present disclosure provides an integrated dispensing injector including an injection tube and a needle tube. The injection tube comprises a main body part for containing liquid medicine and an extension part connected with the main body part, the extension part is provided with a channel communicated with the main body part, and the outer wall of the extension part is provided with a vent groove extending towards the direction far away from the main body part; the needle tube is arranged on the extension part and is provided with an embedded section embedded into the extension part and an exposed section exposed out of the extension part and connected with the embedded section, the exposed section is provided with a puncture needle point, at least one part of the outer surface of the exposed section is provided with a hydrophobic coating, and when dispensing, the needle point of the needle tube is placed into the liquid medicine bottle by the dispensing mechanical arm, and the ventilation groove partially enters the liquid medicine bottle; the core bar is movably arranged in the inner cavity of the injection tube, one end of the core bar is provided with a piston, and the other end of the core bar is provided with a holding part matched with the push-pull device. According to the present disclosure, contamination of liquid medicine can be reduced and dispensing efficiency can be improved.

Description

Integrated dispensing injector and using method thereof

Technical Field

The present disclosure relates to an integrated dispensing syringe and a method of using the same.

Background

With the development of science and technology, mechanical automation is gradually applied to various fields, for example, when dispensing medicines, a medicine dispensing mechanical arm and a medicine dispensing injector can be used for dispensing medicines, so that the labor input is reduced.

At present, a dispensing injector used in cooperation with a dispensing mechanical arm is generally formed by combining a split type injection tube and a needle tube, and the injection tube and the needle tube are connected through an adhesive. When a medicine is dispensed using such a split type dispensing syringe, an adhesive for connecting the syringe and the needle tube may react with the liquid medicine when contacting the liquid medicine, and the liquid medicine may be contaminated. In addition, the liquid medicine bottle usually has pressure difference inside and outside the bottle, so that the liquid medicine may be splashed or difficult to be sucked by the syringe due to abnormal air pressure difference inside and outside the bottle during the process of sucking the liquid medicine, thereby causing low dispensing efficiency.

Disclosure of Invention

The present disclosure has been made in view of the above-described situation, and an object thereof is to provide a dispensing syringe and a method of using the same, which can reduce contamination of a drug solution and improve dispensing efficiency.

The integrated dispensing injector is matched with a dispensing mechanical arm for use, wherein the dispensing mechanical arm comprises a clamping device for clamping the integrated dispensing injector, a push-pull device for pushing and pulling the integrated dispensing injector and a loading device for loading a liquid medicine bottle containing liquid medicine, and is characterized by comprising an injection tube, a needle tube and a core bar, wherein the injection tube comprises a main body part for containing the liquid medicine and an extension part connected with the main body part, the extension part is provided with a channel communicated with the main body part, and the outer wall of the extension part is provided with a vent groove extending towards the direction far away from the main body part; the needle tube is mounted on an extension part of the injection tube, the needle tube is provided with an embedded section embedded into the extension part and an exposed section exposed out of the extension part and connected with the embedded section, the exposed section is provided with a puncture needle point, at least one part of the outer surface of the exposed section is provided with a hydrophobic coating, the main body part and the needle tube form an injection passage through the channel, and when dispensing, the dispensing mechanical arm puts the needle tube into the liquid medicine bottle through the clamping device and enables the vent groove to partially enter the liquid medicine bottle; the core rod is movably arranged in the inner cavity of the injection tube, one end of the core rod is provided with a piston, and the other end of the core rod is provided with a rod body matched with the push-pull device.

In the integrated dispensing injector related to the present disclosure, the hydrophobic coating is provided on at least a portion of the outer surface of the exposed section of the needle tube, so that the attachment of the liquid medicine to the needle tube can be effectively suppressed, and the contamination caused by the falling of the liquid medicine attached to the needle tube during the movement of the needle tube can be reduced. In addition, the outer wall of the extension portion is provided with a vent groove extending in a direction away from the main body portion, and the needle tube is inserted into the liquid medicine bottle and the vent groove is partially inserted into the liquid medicine bottle at the time of dispensing. In this case, the air pressure difference between the inside and the outside of the liquid medicine bottle is balanced by the partial air vent groove located outside the liquid medicine bottle and the partial air vent groove located inside the liquid medicine bottle, whereby the liquid medicine can be easily extracted or pushed, and the dispensing efficiency can be improved.

In the integrated dispensing syringe according to the present disclosure, optionally, a through hole is provided between the main body portion and the extension portion, and the main body portion communicates with the channel via the through hole.

In the integrated dispensing syringe according to the present disclosure, the integrated dispensing syringe may further include a liquid medicine filtering membrane disposed between the main body portion and the extension portion, and the liquid medicine filtering membrane may be disposed in the through hole. This enables the filtration of the chemical solution.

In the integrated dispensing injector according to the present disclosure, optionally, the insertion section of the needle tube is connected to the through hole so that the body portion and the needle tube form an injection passage. This allows the drug solution to enter the body through the needle tube.

In the integrated dispensing syringe according to the present disclosure, the extension portion may be formed integrally with the main body portion. Therefore, the extension part and the main body part can be prevented from being separated from each other during the operation of the integrated dispensing syringe.

In the unitary dispensing syringe to which the present disclosure relates, optionally, the passageway tapers in inner diameter from proximal to distal to the body portion. Thereby, the inner diameter of the channel can be matched with the needle tube by tapering.

In the integrated dispensing syringe according to the present disclosure, the needle tube may be fixed to the channel by forming a fixing portion between the insert molding and the channel. Thereby, the needle tube can be fixed to the fixing section.

In the integrated dispensing syringe according to the present disclosure, optionally, the extension portion has a plurality of vent grooves uniformly arranged on an outer periphery of the extension portion. In this case, the plurality of vent grooves uniformly arranged on the outer periphery of the extension portion can balance the air pressure inside and outside the liquid medicine bottle more efficiently.

In the unitary dispensing syringe to which the present disclosure relates, optionally, the hydrophobic coating comprises a substrate layer, an intermediate layer disposed over the substrate layer, and a surface layer disposed over the intermediate layer. In this case, the base layer can help to arrange the hydrophobic coating on the outer surface of the needle tube, and the surface layer can effectively improve the hydrophobicity of the hydrophobic coating.

In the unitary dispensing syringe to which the present disclosure relates, optionally, the base layer is made of at least one selected from chromium, molybdenum or tungsten, the intermediate layer is made of at least one selected from tungsten carbide, silicon carbide or titanium carbide, and the surface layer is made of at least one selected from amorphous carbon, tetrahedral amorphous carbon, metal-doped amorphous carbon, hydrogen-containing amorphous carbon, tetrahedral hydrogen-containing amorphous carbon, metal-doped hydrogen-containing amorphous carbon, or modified hydrogen-containing amorphous carbon.

According to the present disclosure, it is possible to provide a dispensing syringe and a method of using the same, which can reduce contamination of a liquid medicine and can improve dispensing efficiency.

Drawings

Fig. 1 is a schematic view of an integrated dispensing syringe and dispensing robot in accordance with an embodiment of the present disclosure.

Fig. 2 is a schematic perspective view of an integrated dispensing syringe according to an embodiment of the present disclosure.

Fig. 3 is a schematic sectional view of the integrated dispensing syringe according to the embodiment of the present disclosure along the longitudinal direction.

Fig. 4 is a partially enlarged schematic view of the extension of fig. 3.

Fig. 5 is a schematic sectional view along the short axis of the extension in fig. 2.

FIG. 6 is an enlarged partial schematic view illustrating the exposed section of the syringe of FIG. 4.

Fig. 7 is a schematic view showing a hydrophobic coating layer.

Fig. 8 is a schematic view of the integrated dispensing syringe containing the liquid medicine bottle according to the embodiment of the present disclosure.

Fig. 9 is a flowchart of a method of using the integrated dispensing syringe according to the embodiment of the present disclosure.

Description of reference numerals:

10 … dosage injector, 110 … syringe, 111 … main body part, 1110 … inner cavity, 1111 … cover body, 1112 … through hole, 1113 … liquid medicine filter membrane, 112 … extending part, 1120 … channel, 1121 … vent groove, 1122 … gas filter membrane, 1123 … fixing part, 120 … syringe, 121 … embedding section, 122 … exposing section, 1221 … needle point, 130 … core rod, 131 … rod body, 132 … piston, 20 … dosage mechanical arm, 210 … clamping device, 220 … push-pull device, 230 … loading device, 30 … liquid medicine bottle, 400 … hydrophobic coating, 410 … basal layer, 420 … intermediate layer, 430 … surface layer

Detailed Description

Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In the following description, the same components are denoted by the same reference numerals, and redundant description thereof is omitted. The drawings are schematic and the ratio of the dimensions of the components and the shapes of the components may be different from the actual ones.

The present embodiment relates to an integrated dispensing syringe, which may be referred to as a dispensing syringe or syringe for short. A doctor or the like can dispense an intravenous drug by using the dispensing syringe according to the present embodiment and the dispensing robot. The dispensing syringe of the present embodiment can improve dispensing efficiency and reduce contamination of liquid medicine. The dispensing syringe according to the present embodiment will be described in detail below with reference to the drawings.

Fig. 1 is a schematic diagram of the dispensing syringe 10 according to the embodiment of the present disclosure engaged with a dispensing robot arm 20. Fig. 2 is a schematic perspective view of the dispensing syringe 10 according to the embodiment of the present disclosure. Fig. 3 is a schematic sectional view of the dispensing syringe 10 according to the embodiment of the present disclosure along the longitudinal direction.

In the present embodiment, the injector 10 may include a syringe 110 and a needle tube 120 (see fig. 1 and 2). In some examples, the syringe 10 may further include a core pin 130 (see fig. 1 and 2). The dispensing robot 20 may include a gripping device 210, a push-pull device 220, and a loading device 230. The holding unit 210 may hold the syringe 110 of the syringe 10, the push-pull unit 220 may push-pull the stem 130 of the syringe 10, and the loading unit 230 may load the liquid medicine bottle 30 (see fig. 1) containing the liquid medicine.

In the embodiment shown in fig. 1, the holding unit 210 may be moved in the a direction to place the syringe 120 of the syringe 10 into the liquid medicine bottle 30 or in the b direction to remove the syringe 120 of the syringe 10 from the liquid medicine bottle 30. The push-pull means 220 can push and pull the stem 130, thereby allowing the syringe 10 to push or suck the medical fluid in the medical fluid bottle 30. In addition, in the embodiment shown in fig. 1, the loading unit 30 can be moved in the direction c or the direction d to facilitate the syringe 10 to suck or push the liquid medicine in different liquid medicine bottles 30.

In some examples, the dispensing syringe 10 of the present disclosure may be used in conjunction with a dispensing robotic arm 20 (see fig. 1). Specifically, the dispensing robot 20 may grip the syringe 10 by the gripping device 210 and may push and pull the core pin 130 of the syringe 10 by the push-pull device 220. In addition, the syringe 10 held by the holding unit 210 may have a position corresponding to the loading unit 230 for loading the liquid medicine bottle 30, and the holding unit 210 of the dispensing robot 20 may be moved in the a direction to move the syringe 120 of the syringe 10 into the liquid medicine bottle 30, and the holding unit 210 may be moved in the b direction to move the syringe 120 of the syringe 10 away from the liquid medicine bottle 30.

In this embodiment, the injector 10 may include a syringe 110 and a syringe 120, as described above. In some examples, syringe 10 may also include a core pin 130. Wherein the syringe 110 and the needle tube 120 may form an injection passage, the core pin 130 may be movably disposed in an inner cavity 1110 (described later) of the syringe 110, and the injector 10 may push or suck a medical fluid through the injection passage by pushing or pulling the core pin 130.

In some examples, syringe 110 may include a body portion 111 and an extension portion 112 (see fig. 2). The main body 111 may be formed with an inner cavity 1110 for receiving a medical solution, and the extension part 112 may be connected to the main body 111.

In some examples, the body portion 111 may be elongated. For example, the outer contour of the body 111 may have a columnar structure such as a cylindrical shape or a prismatic shape.

In some examples, as described above, the body portion 111 may have an internal cavity 1110, and the internal cavity 1110 may be used to contain a medical fluid. In some examples, the diameter may be the same throughout the lumen 1110. Thereby, the core bar 130 can be easily pushed or pulled within the internal cavity 1110.

In some examples, the main body 111 may be made of plastic or the like. For example, the material of the main body 111 may be polypropylene or polyvinyl chloride. However, the present disclosure is not limited thereto, and the main body 111 may be made of other materials, such as glass.

In some examples, the body portion 111 may be transparent. This facilitates the external observation of the medical fluid contained in the internal cavity 1110. In some examples, the outer wall of the main body 111 may be provided with a scale (not shown). In some examples, the scale on the outer wall of the main body portion 111 may increase in order from the end near the extension portion 112 to the end far from the extension portion 112. For example, 5ml, 10ml, 15ml, 20ml, 25ml, 30 ml. This facilitates reading of the amount of the chemical liquid in the main body 111.

In some examples, an end of the main body 111 distal from the extension 112 may be provided with a cover 1111. In this case, the holder 210 can hold the lid 1111, thereby preventing the syringe 10 from sliding up and down on the holder 210 (see fig. 1). In some examples, the cover 1111 may protrude outward from the main body portion 111 in a radial direction of the main body portion 111.

In some examples, an end of the body portion 111 near the extension 112 may be provided with a through hole 1112. The body portion 111 may communicate with the extension portion 112 through a through hole 1112.

In some examples, the extension 112 may be continuously integrally formed with the body portion 111. This can prevent the extension portion 112 and the body portion 111 from being separated from each other when the dispensing syringe 10 is operated. But examples of the present disclosure are not limited thereto, and the extension part 112 may be connected with the body part 111 in other ways. The extension portion 112 is connected to the main body portion 111 by, for example, adhesion, screwing, or engagement.

In some examples, the extension 112 may be elongated. In some examples, the outer diameter of the extension 112 may taper from an end proximal to the body 111 to an end distal to the body 111. For example, the extension 112 may be generally conical. Thereby facilitating entry of the extension 112 into the liquid medicine bottle 30.

In some examples, the extension 112 may have a channel 1120 running through it lengthwise. In some examples, the channel 1120 may be tapered. That is, the inner diameter of the channel 1120 may gradually decrease from an end close to the body portion 111 to an end far from the body portion 111. Examples of the present disclosure are not limited thereto and the channel 1120 may have other shapes. For example, the channel 1120 may be cylindrical, etc. In some examples, when the extension 112 is connected with the body portion 111, the channel 1120 may be in communication with the lumen 1110 of the body portion 111. In some examples, the inner diameter of the channel 1120 near an end of the body portion 111 may be equal to the inner diameter of the lumen 1110 of the body portion 111 near an end of the extension 112. Additionally, in some examples, the lumen 1110 of the body portion 111 may communicate with the channel 1120 of the extension 112 via the through-holes 1112 of the body portion 111.

In some examples, a drug solution filtering membrane 1113 (see fig. 3) may be disposed between the extension portion 112 and the body portion 111. In some examples, the drug solution filtering membrane 1113 may include a large number of filtering holes. In this case, when the chemical enters the extension part 112 from the main body part 111, impurities in the chemical can be filtered effectively by the chemical filtering membrane 1113.

In some examples, the drug solution filtering membrane 1113 may be disposed in the through hole 1112 of the main body 111. In some examples, the drug solution filter membrane 1113 may be no smaller than the through-hole 1112. In some examples, the drug solution filter 1113 may fill the through hole 1112. In some examples, the drug solution filtering membrane 1113 may cover the through hole 1112. Thus, impurities in the liquid medicine can be effectively filtered.

In some examples, the drug solution filtering membrane 1113 may be fixed between the main body 111 and the extension 112 by a snap or screw method. For example, the liquid medicine filtering membrane 1113 may include a filter screen (not shown) and a housing (not shown) for carrying the filter screen, and the housing may have a snap-fit structure or a screw-fit structure. In this case, the chemical filtering membrane 1113 may be fixed between the main body 111 and the extension 112 by engagement or screwing. However, the present disclosure is not limited thereto, and in some examples, the medical fluid filtering membrane 1113 may be fixed between the main body 111 and the extension portion 112 by other methods, for example, the medical fluid filtering membrane 1113 may be fixed by adhesion.

Fig. 4 is a partially enlarged schematic view of the extension 112 of fig. 3. Fig. 5 is a schematic sectional view of the extension 112 along the direction a-a'.

In some examples, the extension 112 is integrally formed with the body 111. In some examples, the extension part 112 and the main body part 111 of the injection tube 110 can be integrally molded by injecting plastic in a molten state into a mold cavity through an insert injection molding process and cooling the injection tube 110.

In some examples, a vent groove 1121 may be provided on an outer wall of the extension 112. In some examples, a vent groove 1121 extending in a direction away from the main body portion 111 may be provided at an outer wall of the extension portion 112. In some examples, the vent groove 1121 is disposed on an outer wall of the extension 112 along a length direction of the extension 112. In some examples, a plurality of vent slots 1121 may be provided on the outer wall of the extension 112. In some examples, the plurality of vent slots 1121 may be uniformly disposed on the outer wall of the extension 112.

In some examples, the cross-section of the vent groove 1121 along the direction a-a' may be rectangular (see fig. 5). In other examples, the width of the cross section of the vent groove 1121 along the direction a-a' may be narrow from inside to outside, such as a trapezoid, so as to prevent the plug scraps from blocking the vent groove 1121 during the puncturing process of the plug of the liquid medicine bottle 30 by the syringe 10.

In some examples, the extension 112 may partially enter the liquid medicine bottle 30. Specifically, when the extension portion 112 partially enters the liquid medicine bottle 30, a portion of the vent groove 1121 may be located outside the liquid medicine bottle 30, and another portion of the vent groove 1121 may be located inside the liquid medicine bottle 30. In this case, the space of the liquid medicine bottle 30 is communicated with the ambient air pressure through the partial ventilation groove 1121 located outside the liquid medicine bottle 30 and the partial ventilation groove 1121 located inside the liquid medicine bottle 30, so that the air pressure inside and outside the liquid medicine bottle 30 can be balanced, and the problem that the liquid medicine is splashed or is difficult to be sucked by the syringe 10 due to the abnormal air pressure difference inside and outside the bottle during the liquid medicine suction process can be effectively avoided. This can improve the dispensing efficiency.

In the present embodiment, as described above, the injector 10 may include the syringe 120 (see fig. 2). In some examples, needle cannula 120 may be embedded in extension 112. In some examples, needle cannula 120 may have an insertion section 121 inserted into extension 112, and an exposed section 122 exposed from extension 112 and connected to insertion section 121. In some examples, the exposed section 122 may have a needle tip 1221 for piercing (see fig. 4).

In some examples, needle cannula 120 may be inserted into passage 1120 of extension 112. In some examples, the plastic part in a molten state is coated on the outer circumference of the needle tube 120 by insert injection molding, so that the needle tube 120 and the channel 1120 of the extension part 112 form a fixing part 1125 to be fixed to the channel 1120 (see fig. 4). Thus, contamination of the chemical solution can be reduced.

In some examples, a retainer 1125 may be formed between the needle cannula 120 and the channel 1120, and the needle cannula 120 may be secured to the channel 1120 by the retainer 1125. In some examples, retainer 1125 may be formed by cooling molten plastic between needle 120 and extension 112 by insert molding. In some examples, the fixation portion 1125 may be located on an inner wall of the extension 112.

In some examples, body portion 111 may form an injection path with needle 120 via channel 1120. In some examples, the end of needle cannula 120 inserted into extension 112 may be connected to through-hole 1112 of body 111, thereby enabling an injection path with body 111 via channel 1112. In some examples, the end of the needle 120 inserted into the extension 112 may abut against the through hole 1112 of the body 111. In other examples, the end of the needle tube 120 inserted into the extension 112 may be connected to the through hole 1112 of the main body 111 by, for example, a connecting tube (not shown).

FIG. 6 is an enlarged partial schematic view illustrating the exposed section 122 of the syringe 120 of FIG. 4. Fig. 7 is a schematic view illustrating the hydrophobic coating 400.

In some examples, a hydrophobic coating 400 (see fig. 6) may be disposed on the outer surface of the needle cannula 120. In some examples, a hydrophobic coating 400 may be disposed on at least a portion of an outer surface of the exposed section 122 of the needle cannula 120. In some examples, a hydrophobic coating 400 may be disposed on an outer surface of the extension 112. During dispensing, the liquid medicine may adhere to the surface of the needle tube 120 due to the tension of the water, and the liquid medicine adhering to the surface of the needle tube 120 may fall and contaminate when the dispensing syringe 10 is moved to another position. In this case, by providing the hydrophobic coating 400 on the outer surface of the needle tube 120, it is possible to effectively suppress the adhesion of the drug solution to the outer surface of the needle tube 120, and thus to reduce contamination.

In some examples, the hydrophobic coating 400 may include a base layer 410, an intermediate layer 420 disposed over the base layer 410, and a surface layer 430 disposed over the intermediate layer 420. In some examples, the hydrophobic coating 400 may be applied to the surface of the exposed section 122 of the needle cannula 120 via chemical vapor deposition.

Specifically, the outer surface of the needle tube 120 may be first cleaned; next, a base layer 410 is coated on the outer surface of the cleaned needle tube 120 by chemical vapor deposition; next, an intermediate layer 420 is coated on the base layer 410 by chemical vapor deposition; finally, a surface layer 430 is applied over the intermediate layer 420 by chemical vapor deposition.

In some examples, the base layer 410 may be made of at least one selected from chromium, molybdenum, or tungsten.

In some examples, the intermediate layer 420 may be made of at least one selected from tungsten carbide, silicon carbide, or titanium carbide.

In some examples, the surface layer 430 may be made of at least one selected from amorphous carbon (a-C), tetrahedral amorphous carbon (ta-C), metal doped amorphous carbon (a-C: Me, wherein Me may be tungsten, titanium, molybdenum, aluminum, or the like), hydrogen containing amorphous carbon (a-C: H), tetrahedral hydrogen containing amorphous carbon (ta-C: H), metal doped hydrogen containing amorphous carbon (a-C: H: Me, wherein Me may be tungsten, titanium, molybdenum, aluminum, or the like), or modified hydrogen containing amorphous carbon (a-C: H: X, wherein X may be silicon, oxygen, nitrogen, fluorine, boron, or the like).

In some examples, preferably, the base layer 410 may be made of chromium, the intermediate layer 420 may be made of tungsten carbide, and the surface layer 430 may be made of hydrogen-containing amorphous carbon (a-C: H).

Fig. 8 is a schematic view of the dispensing syringe 10 according to the embodiment of the present disclosure being inserted into the liquid medicine bottle 30.

In some examples, the syringe 10 may enter the liquid drug bottle 30 by piercing the sealing means of the liquid drug bottle 30, for example, with the needle tip 1221 of the needle cannula 120. In some examples, the length of needle cannula 120 may be no less than the length of extension 112. In this case, the needle tube 120 can be fitted into the extension 112 so as to come into contact with the through hole 1112 of the body 111. Examples of the present disclosure are not limited thereto and the length of needle cannula 120 may be less than the length of extension 112. In some examples, the length of the protrusion from the needle tube 120 from the extension 112 is less than the height of the liquid medicine bottle 30, in which case the extension 112 can partially enter the liquid medicine bottle 30, thereby enabling the vent groove 1121 to partially enter the liquid medicine bottle 30.

In some examples, the vent groove 1121 may be partially disposed into the liquid medicine bottle 30 after the needle 120 is inserted into the liquid medicine bottle 30 (see fig. 8). In this case, when the dispensing syringe 10 is operated, the liquid medicine bottle 30 can be brought into gas communication with the atmosphere by positioning a part of the vent groove 1121 and another part of the vent groove 1121 outside and inside the liquid medicine bottle 30, respectively, and the air pressures inside and outside the liquid medicine bottle 30 can be balanced.

In some examples, as described above, the syringe 10 may also include a core pin 130 (see fig. 2). In some examples, the mandrel 130 may be disposed within the internal cavity 1110 of the body portion 111 and may be movable within the internal cavity 1110. In this case, when the needle tube 120 is inserted into the liquid medicine bottle 30 and the needle tip 1221 is submerged into the liquid medicine in the liquid medicine bottle 30, the syringe 10 can push or suck the liquid medicine in the liquid medicine bottle 30 by pushing or pulling the stem 130 (see fig. 1). Specifically, when the stem 130 is pushed, the drug solution can be pushed from the inner cavity 1110 of the body 111 into the drug solution bottle 30 through the injection passage formed by the body 111 and the needle tube 120; when the stem 130 is pulled, the drug solution can be sucked from the drug solution bottle 30 into the cavity 1110 of the body 111 through the injection path formed by the body 111 and the needle tube 120.

In some examples, the stem 130 may include a shaft 131 and a plunger 132, and the plunger 132 may be disposed at an end of the shaft 131 near the needle 120 (see fig. 3).

In some examples, the shaft 131 may be elongated. In some examples, the outer diameter of the shaft 131 may be no greater than the diameter of the inner cavity 1110 of the body portion 111. In some examples, the length of the shaft 131 may be no less than the length of the inner cavity 1110 of the body portion 111.

In some examples, piston 132 may have an outer diameter that matches the inner cavity 1110 of body portion 111 to enable piston 132 to move along the walls of inner cavity 1110. In some examples, the piston 132 may be made of an elastic material.

In some examples, the piston 132 may be integrally formed with the rod 131. In other examples, the piston 132 may be coupled to the rod 131 by a snap-fit. But examples of the present disclosure are not limited thereto, and the rod 131 may be connected with the piston 132 in other ways. The rod 131 is coupled to the piston 132, for example, by bonding, screwing, or the like.

In some examples, the stem 131 of the stem 130 may cooperate with a push-pull device 220 of the dispensing robot 20 (see fig. 1). In some examples, the push-pull device 220 may be connected to the lever 131 and push or pull the lever 131 when using the dispensing syringe 10 and the dispensing robot 20 for dispensing. In this case, the push-pull device 220 of the dispensing arm 20 pushes or pulls the stem 130, so that the drug solution can be pushed or sucked.

However, the disclosed example is not limited thereto, the core rod 130 may be composed of the piston 132, and the push-pull device 220 may be an air pump device (not shown). In this case, the air pump device is connected to the inner cavity 1110 of the main body 111, and the air pressure in the inner cavity 1110 is increased by the air pump device to push the piston 132 in a direction approaching the needle tube 120, thereby pushing the liquid medicine; the medical fluid can be sucked by reducing the air pressure in the inner cavity 1110 by the air pump means to pull the piston 132 in a direction away from the needle tube 120.

Fig. 9 is a flowchart of a method of using the dispensing syringe 10 according to the embodiment of the present disclosure. Hereinafter, a method of using the dispensing syringe 10 according to the example of the present embodiment will be described in detail with reference to fig. 9.

In the present embodiment, as shown in fig. 9, the dispensing by the cooperation of the syringe 10 and the dispensing robot 20 may include the steps of:

the dispensing syringe 10 is fixed to the gripper 210 of the dispensing arm 20, and the liquid medicine bottle 30 is placed on the loader 230 of the dispensing arm 20 (step S100).

In some examples, the gripping device 210 of the dispensing robot 20 is secured to the dispensing robot 20 by gripping the cover 1111 of the dispensing syringe 10 (see fig. 1).

In some examples, the loading device 230 may hold the vial of the liquid medicine bottle 30 to be fixed on the loading device 230.

In some examples, the syringe 10 may be located near the loading device 230, and in some examples, the syringe 10 may also be located directly above the mouth of the liquid medicine bottle 30.

The needle tube 120 of the dispensing syringe 10 is inserted into the liquid medicine bottle 30 (step S200).

In some examples, the gripping device 210 of the dispensing robot 20 may be moved in the a direction (see fig. 1) to cause the needle cannula 120 to pierce the liquid medicine bottle 30.

In some examples, the dispensing syringe 10 has a vent groove 1121, and the needle tube 120 enters the liquid drug bottle 30 with the vent groove 1121 partially entering the liquid drug bottle 30.

Push and pull the core rod 130 of the dispensing syringe 10 to push or suck the liquid medicine in the liquid medicine bottle 30 (step S300)

In some examples, the push-pull device 220 of the dispensing robot 20 may push or pull the core rod 130 through the cap 1111 holding the dispensing syringe 10, so that the syringe 10 pushes or sucks the liquid medicine in the liquid medicine bottle 30.

The needle tube 120 of the dispensing syringe 10 is separated from the liquid medicine bottle 30(S400)

In some examples, the gripping device 210 of the dispensing robot 20 may be moved in the direction b (see fig. 1) to cause the syringe 120 to withdraw the vial 30.

According to the dispensing syringe 10 and the method of using the same of the present embodiment, contamination of the liquid medicine can be reduced and dispensing efficiency can be improved.

While the present disclosure has been described in detail in connection with the drawings and examples, it is to be understood that the above description is not intended to limit the invention in any way. Those skilled in the art can make modifications and variations to the present invention as needed without departing from the true spirit and scope of the invention, and such modifications and variations are within the scope of the invention.

Claims

1. An integrated dispensing injector is a dispensing injector matched with a dispensing mechanical arm for use, the dispensing mechanical arm comprises a clamping device for clamping the integrated dispensing injector, a push-pull device for pushing and pulling the integrated dispensing injector and a loading device for loading a liquid medicine bottle containing liquid medicine, and is characterized by comprising an injection tube, a needle tube and a core rod,

the syringe comprises a main body part for containing liquid medicine and an extension part connected with the main body part, wherein the extension part is provided with a channel communicated with the main body part, a vent groove extending towards the direction far away from the main body part is arranged on the outer wall of the extension part, and the width of the cross section of the vent groove is wide and narrow from inside to outside;

the needle tube is mounted on an extension part of the injection tube, the needle tube is provided with an embedded section embedded into the extension part and an exposed section exposed out of the extension part and connected with the embedded section, the exposed section is provided with a puncture needle point, at least one part of the outer surface of the exposed section is provided with a hydrophobic coating, the main body part and the needle tube form an injection passage through the channel, and when dispensing, the dispensing mechanical arm puts the needle tube into the liquid medicine bottle through the clamping device and enables the vent groove to partially enter the liquid medicine bottle;

the core rod is movably arranged in the inner cavity of the injection tube, one end of the core rod is provided with a piston, and the other end of the core rod is provided with a rod body matched with the push-pull device.

2. The integrated dispensing syringe of claim 1, wherein:

a through hole is formed between the main body part and the extending part, and the main body part is communicated with the channel through the through hole.

3. An integrated dispensing syringe according to claim 2, characterized in that:

the integrated dispensing syringe further comprises a liquid medicine filtering membrane arranged between the main body part and the extension part, and the liquid medicine filtering membrane is arranged in the through hole.

4. An integrated dispensing syringe according to claim 2, characterized in that:

the insertion section of the needle tube is connected to the through hole so that the main body and the needle tube form the injection passage.

5. The integrated dispensing syringe of claim 1, wherein:

the extension portion is continuously integrally formed with the main body portion.

6. The integrated dispensing syringe of claim 1, wherein:

the passage has an inner diameter that decreases from proximate the body portion to distal the body portion.

7. The integrated dispensing syringe of claim 1, wherein:

the needle tube is fixed in the channel by forming a fixing part between the insert injection molding and the channel.

8. The integrated dispensing syringe of claim 1, wherein:

the extension portion has a plurality of vent grooves uniformly arranged at an outer circumference of the extension portion.

9. The integrated dispensing syringe of claim 1, wherein:

the hydrophobic coating includes a base layer, an intermediate layer disposed over the base layer, and a surface layer disposed over the intermediate layer.

10. The integrated dispensing syringe of claim 9, wherein:

the base layer is made of at least one selected from chromium, molybdenum or tungsten,

the intermediate layer is made of at least one selected from tungsten carbide, silicon carbide or titanium carbide,

the surface layer is made of at least one selected from amorphous carbon, tetrahedral amorphous carbon, metal-doped amorphous carbon, hydrogen-containing amorphous carbon, tetrahedral hydrogen-containing amorphous carbon, metal-doped hydrogen-containing amorphous carbon, or modified hydrogen-containing amorphous carbon.