CN112889820A - Compound quaternary ammonium salt disinfectant and preparation method and use method thereof - Google Patents
Compound quaternary ammonium salt disinfectant and preparation method and use method thereof Download PDFInfo
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Abstract
The invention discloses a compound quaternary ammonium salt disinfectant, a preparation method and a use method thereof, wherein the compound quaternary ammonium salt disinfectant comprises 16-20 wt% of quaternary ammonium salt bactericide, 0.5-3 wt% of metal ion chelating agent, 0.5-10 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of mixed liquor to 8-10, the compound quaternary ammonium salt disinfectant also comprises 0.5-1.5 wt% of benzotriazole and 1-5 wt% of polyglycerol ether, the molar ratio of ethoxy to glyceryl in the polyglycerol ether is 26:1, and the balance is water. The compound quaternary ammonium salt disinfectant provided by the invention has low ecological toxicity and good environmental compatibility, has good bactericidal property at low concentration after dilution, has a corrosion inhibition effect on metal aluminum, can be used for surface disinfection of aluminum products, has a wide application range, can be used in a low-temperature environment by being matched with a diluent, and has good practicability.
Description
Technical Field
The invention relates to the technical field of disinfectant products, in particular to a compound quaternary ammonium salt disinfectant and a preparation method and a use method thereof.
Background
The quaternary ammonium salt disinfectant has the characteristics of low concentration, effectiveness, small side effect, no color, low stimulation, safety and the like, so the quaternary ammonium salt disinfectant is widely used as a sterilization disinfectant in the fields of medical treatment, surgical products, family personal, public health and the like. However, the inventor of the present invention finds that the quaternary ammonium salt disinfectant with a single disinfectant component has limited bactericidal effect in certain use environments, can generate drug resistance after being used alone for a long time, and can generate corrosion to different degrees on the surface of a disinfected metal product, so that the existing quaternary ammonium salt disinfectant needs to be compounded to exert the synergistic effect among the components so as to improve the bactericidal and disinfectant effects and protect the metal product to be disinfected, thereby expanding the use range of the quaternary ammonium salt disinfectant.
In addition, the quaternary ammonium salt disinfectant can frequently contact with a human body and be repeatedly used in the daily disinfection process, such as hand disinfection, disinfection of clothes and daily necessities, and indoor and outdoor environment disinfection, so people put forward higher requirements on the quaternary ammonium salt disinfectant, such as low toxicity, low concentration, and the requirement of the effect of high-efficiency sterilization and disinfection under the extremely low concentration as far as possible, and the use requirement of low freezing point and the use under the low-temperature environment such as winter. Therefore, how to design or develop a compound quaternary ammonium salt disinfectant with good bactericidal property at low concentration and wide application range becomes a technical problem to be solved by the technical personnel in the field.
Disclosure of Invention
Aiming at the defects or improvement requirements of the prior art, the invention provides a compound quaternary ammonium salt disinfectant, a preparation method and a use method thereof.
The purpose of the invention is realized by the following technical scheme:
according to one aspect of the invention, the compound quaternary ammonium salt disinfectant comprises 16 wt% -20 wt% of quaternary ammonium salt disinfectant, 0.5 wt% -3 wt% of metal ion chelating agent, 0.5 wt% -10 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of mixed liquor to 8-10, the compound quaternary ammonium salt disinfectant also comprises 0.5 wt% -1.5 wt% of benzotriazole and 1 wt% -5 wt% of polyglycerol ether, the molar ratio of ethoxy to glyceryl in the polyglycerol ether is 26:1, and the balance is water.
Further, the quaternary ammonium salt bactericide at least comprises one of benzalkonium chloride, benzalkonium bromide, didecyldimethyl ammonium chloride, didecyldimethyl ammonium bromide, decylmethylhydroxyethyl/hydroxypropyl ammonium chloride, hexadecyltrimethyl ammonium bromide and ethylene (didodecyldimethyl ammonium bromide).
Further, the metal ion chelating agent at least comprises one of ethylene diamine tetraacetic acid and sodium salt thereof, nitrilotriacetic acid and sodium salt thereof, sodium gluconate, sodium citrate, hydroxyethylidene diphosphonic acid and sodium salt thereof, ethylene diamine tetramethylene phosphonic acid and sodium salt thereof, 2-phosphate-1, 2, 4-tricarboxylic acid butane, 2-hydroxyphosphonoacetic acid and sodium salt thereof.
Further, the water-soluble amphoteric surfactant comprises at least one of cocamidopropyl betaine, dodecyl dimethyl betaine, dodecyl propyl betaine, cocamidopropyl ammonium oxide, dodecyl propyl ammonium oxide, and dodecyl dimethyl amine oxide.
Further, the strong alkali solution at least comprises one of sodium hydroxide aqueous solution, potassium hydroxide aqueous solution, sodium carbonate aqueous solution and potassium carbonate aqueous solution.
The invention also provides a compound quaternary ammonium salt disinfectant, which comprises 17-19 wt% of quaternary ammonium salt, 1-2 wt% of metal ion chelating agent, 3-7 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of the mixed liquor to 8-10; the compound quaternary ammonium salt disinfectant also comprises 0.8-1.2 wt% of benzotriazole, 2-4 wt% of polyglycerol ether and the balance of water.
According to another aspect of the invention, the preparation method of the compound quaternary ammonium salt disinfectant is provided: firstly, adding 16-20 wt% of quaternary ammonium salt bactericide, 0.5-3 wt% of metal ion chelating agent, 0.5-10 wt% of water-soluble amphoteric surfactant, 0.5-1.5 wt% of benzotriazole, 1-5 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the mixture is fully dissolved, then adding strong alkaline solution to adjust the pH of the mixed solution in the reaction kettle to 8-10, and preparing the compound quaternary ammonium salt disinfectant for later use by filling.
According to a third aspect of the invention, there is provided a method of using the above compound quaternary ammonium salt disinfectant: the compound quaternary ammonium salt disinfectant is diluted by water for use, and the dilution mass ratio is 1: 50-600.
The invention also provides another using method of the compound quaternary ammonium salt disinfectant, which comprises the following steps: diluting the compound quaternary ammonium salt disinfectant with a mixed diluent prepared from water and a water-soluble alcohol solvent, wherein the dilution mass ratio of the compound quaternary ammonium salt disinfectant to the mixed diluent is 1:50-600, and the volume ratio of water to the water-soluble alcohol solvent in the mixed diluent is 1: 1-9:1.
The invention also provides another using method of the compound quaternary ammonium salt disinfectant, which comprises the following steps: diluting the compound quaternary ammonium salt disinfectant with a low-temperature synergistic solvent for use, wherein the dilution mass ratio is 1: 50-600; the low-temperature synergistic solvent comprises 25-30 wt% of halogenated salt, 25-30 wt% of water-soluble alcohol solvent and the balance of water.
Further, the halogenated salt at least comprises one of sodium chloride and calcium chloride.
Further, the water-soluble alcohol solvent at least comprises one of methanol, ethanol, ethylene glycol, propylene glycol, isopropanol, 1, 3-butanediol, glycerol, diethylene glycol and triethylene glycol.
Compared with the prior art, the technical scheme of the invention has the following advantages:
the compound quaternary ammonium salt disinfectant provided by the invention has low ecological toxicity, good environmental compatibility, easy storage and long service cycle; the compound quaternary ammonium salt disinfectant can be prepared by compounding the existing quaternary ammonium salt disinfectant, and the preparation process is simple; the prepared compound quaternary ammonium salt disinfectant still has high-efficiency bactericidal performance under the low concentration of 600 times of dilution, has a corrosion inhibition effect on metal aluminum, can be used for surface disinfection of aluminum products, and has a wide application range; in addition, the compound quaternary ammonium salt disinfectant can be matched with diluent to be used in a low-temperature environment, has good practicability and has wide industrial popularization value.
Detailed Description
Various other advantages and benefits will become apparent to those of ordinary skill in the art upon reading the following detailed description of the specific embodiments. The present invention is described in further detail by the following specific embodiments, and the specific examples described in the following embodiments of the present invention are merely illustrative of the specific embodiments of the present invention and are intended to be illustrative of the present invention and are not to be construed as limiting the present invention.
The invention provides a compound quaternary ammonium salt disinfectant, which comprises 16-20 wt% of quaternary ammonium salt bactericide, 0.5-3 wt% of metal ion chelating agent, 0.5-10 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of mixed liquor to 8-10, and also comprises 0.5-1.5 wt% of benzotriazole and 1-5 wt% of polyglycerol ether, wherein the molar ratio of ethoxy to glyceryl in the polyglycerol ether is 26:1, and the balance is water.
The invention also provides a preferable example of the compound quaternary ammonium salt disinfectant, wherein the compound quaternary ammonium salt disinfectant comprises 17 wt% -19 wt% of quaternary ammonium salt, 1 wt% -2 wt% of metal ion chelating agent, 3 wt% -7 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of the mixed liquor to 8-10; the compound quaternary ammonium salt disinfectant also comprises 0.8-1.2 wt% of benzotriazole, 2-4 wt% of polyglycerol ether and the balance of water.
Further, the quaternary ammonium salt bactericide comprises one or more of benzalkonium chloride, benzalkonium bromide, didecyldimethyl ammonium chloride, didecyldimethyl ammonium bromide, decylmethylhydroxyethyl/hydroxypropylammonium chloride, cetyltrimethyl ammonium bromide, and ethylene (didodecyldimethyl ammonium bromide).
Further, the metal ion chelating agent comprises one or more of ethylene diamine tetraacetic acid and sodium salt thereof, nitrilotriacetic acid and sodium salt thereof, sodium gluconate, sodium citrate, hydroxyethylidene diphosphonic acid and sodium salt thereof, ethylene diamine tetra methylene phosphonic acid and sodium salt thereof, 2-phosphate-1, 2, 4-tricarboxylic acid butane, 2-hydroxyphosphonoacetic acid and sodium salt thereof.
Further, the water-soluble amphoteric surfactant comprises one or more of cocamidopropyl betaine, dodecyl dimethyl betaine, dodecyl propyl betaine, cocamidopropyl ammonium oxide, dodecyl propyl ammonium oxide, dodecyl dimethyl amine oxide.
Further, the strong alkali solution comprises one or more of sodium hydroxide aqueous solution, potassium hydroxide aqueous solution, sodium carbonate aqueous solution and potassium carbonate aqueous solution.
In addition, the invention provides a preparation method of the compound quaternary ammonium salt disinfectant, which comprises the following steps: adding 16-20 wt% of quaternary ammonium salt bactericide, 0.5-3 wt% of metal ion chelating agent, 0.5-10 wt% of water-soluble amphoteric surfactant, 0.5-1.5 wt% of benzotriazole, 1-5 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the mixture is fully dissolved, adding strong alkaline liquid to adjust the pH of the mixed liquid in the reaction kettle to 8-10, and preparing the compound quaternary ammonium salt disinfectant for later use.
Furthermore, the invention provides three using methods of the compound quaternary ammonium salt disinfectant.
The use method I comprises the following steps: the compound quaternary ammonium salt disinfectant is diluted by water for use, and the dilution mass ratio is 1: 50-600.
The use method II comprises the following steps: diluting the compound quaternary ammonium salt disinfectant with a mixed diluent prepared from water and a water-soluble alcohol solvent, wherein the dilution mass ratio of the compound quaternary ammonium salt disinfectant to the mixed diluent is 1:50-600, and the volume ratio of water to the water-soluble alcohol solvent in the mixed diluent is 1: 1-9:1. The water-soluble alcohol solvent can reduce the freezing point of the diluted liquid system, has good compatibility, ensures that the diluted disinfectant does not freeze in the low-temperature transportation and use processes such as winter and the like, is suitable for being used as a disinfectant in a cold chain environment, enlarges the application range of the compound quaternary ammonium salt disinfectant, and has good practicability.
The using method comprises the following steps: diluting the compound quaternary ammonium salt disinfectant with a low-temperature synergistic solvent for use, wherein the dilution mass ratio is 1: 50-600; the low-temperature synergistic solvent comprises 25-30 wt% of halogenated salt, 25-30 wt% of water-soluble alcohol solvent and the balance of water. Further, the halogenated salt at least comprises one of sodium chloride and calcium chloride.
Further, the water-soluble alcohol solvent comprises one or more of methanol, ethanol, ethylene glycol, propylene glycol, isopropyl alcohol, 1, 3-butylene glycol, glycerol, diethylene glycol and triethylene glycol.
Example 1:
the embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 10 wt% of didecyl dimethyl ammonium bromide, 10 wt% of benzalkonium chloride, 1 wt% of ethylene diamine tetraacetic acid disodium, 5 wt% of cocamidopropyl betaine, 1 wt% of benzotriazole, 2 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by adopting a sodium carbonate solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: firstly, adding 10 wt% of didecyl dimethyl ammonium bromide, 10 wt% of benzalkonium chloride, 1 wt% of ethylene diamine tetraacetic acid, 5 wt% of cocamidopropyl betaine, 1 wt% of benzotriazole, 2 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the solution is fully dissolved, adding a sodium carbonate solution to adjust the pH of a mixed solution in the reaction kettle to 8-10, and preparing the compound quaternary ammonium salt disinfectant for later use by filling.
Example 2:
the embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 10 wt% of didecyl dimethyl ammonium bromide, 10 wt% of benzalkonium bromide, 1 wt% of nitrilotriacetic acid, 5 wt% of dodecyl dimethyl betaine, 0.8 wt% of benzotriazole, 4 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by adopting a sodium hydroxide solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: firstly, adding 10 wt% of didecyl dimethyl ammonium bromide, 10 wt% of benzalkonium bromide, 1 wt% of nitrilotriacetic acid, 5 wt% of dodecyl dimethyl betaine, 0.8 wt% of benzotriazole, 4 wt% of polyglyceryl ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the materials are fully dissolved, then adding a sodium hydroxide solution to adjust the pH of a mixed solution in the reaction kettle to be 8-10, and preparing the compound quaternary ammonium salt disinfectant for later use by filling.
Example 3:
the embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 10 wt% of didecyl dimethyl ammonium chloride, 10 wt% of benzalkonium bromide, 0.2 wt% of sodium gluconate, 0.5 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of sodium citrate, 6 wt% of dodecyl propyl amine oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by adopting a potassium hydroxide solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: firstly, adding 10 wt% of didecyl dimethyl ammonium chloride, 10 wt% of benzalkonium bromide, 0.2 wt% of sodium gluconate, 0.5 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of sodium citrate, 6 wt% of dodecyl propyl amine oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglyceryl ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the materials are fully dissolved, adding a potassium hydroxide solution to adjust the pH of a mixed solution in the reaction kettle to 8-10, and preparing the compound quaternary ammonium salt disinfectant to be filled for later use.
When the compound quaternary ammonium salt disinfectant provided in examples 1 to 3 is used, the compound quaternary ammonium salt disinfectant is diluted with water according to a mass ratio of 1:600, and then used for wiping disinfection or spraying disinfection of the surface of an environmental object.
Example 4:
the embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 10 wt% of didecyl dimethyl ammonium chloride, 5 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 5 wt% of benzalkonium bromide, 0.2 wt% of sodium gluconate, 0.5 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of sodium citrate, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by using a sodium carbonate solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: firstly, adding 10 wt% of didecyl dimethyl ammonium chloride, 5 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 5 wt% of benzalkonium bromide, 0.2 wt% of sodium gluconate, 0.5 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of sodium citrate, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the components are fully dissolved, then adding a sodium carbonate solution to adjust the pH value of a mixed solution in the reaction kettle to 8-10, preparing the compound quaternary ammonium salt disinfectant, and filling for later use.
When the compound quaternary ammonium salt disinfectant provided by the embodiment 4 is used, the following components are added: ethanol ═ 7: 3 (volume ratio) to prepare mixed diluent, and diluting the compound quaternary ammonium salt disinfectant and the mixed diluent according to the mass ratio of 1:600 for wiping disinfection or spraying disinfection of the surface of an environmental object.
Example 5:
the embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 8 wt% of didecyl dimethyl ammonium bromide, 8 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 3 wt% of benzalkonium bromide, 0.8 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of hydroxyethylidene diphosphonic acid, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by adopting a potassium carbonate solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: adding 8 wt% of didecyl dimethyl ammonium bromide, 8 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 3 wt% of benzalkonium bromide, 0.8 wt% of disodium edetate, 0.3 wt% of hydroxyethylidene diphosphonic acid, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the mixture is fully dissolved, adding a potassium carbonate solution to adjust the pH of the mixed solution in the reaction kettle to be 8-10, preparing the compound quaternary ammonium salt disinfectant, and filling for later use.
When the compound quaternary ammonium salt disinfectant provided in example 5 is used, the following components are added: ethylene glycol: preparing mixed diluent from isopropanol (volume ratio) of 6:1:3, diluting the compound quaternary ammonium salt disinfectant and the mixed diluent according to the mass ratio of 1:600, and then wiping and disinfecting or spraying the surface of an environmental object for disinfection.
Example 6
The embodiment provides a compound quaternary ammonium salt disinfectant which comprises: 8 wt% of didecyl dimethyl ammonium bromide, 8 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 3 wt% of benzalkonium bromide, 0.8 wt% of disodium ethylene diamine tetraacetate, 0.3 wt% of hydroxyethylidene diphosphonic acid, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglyceryl ether and the balance of water, and the pH of the mixed solution is adjusted to 8-10 by using a potassium carbonate solution.
The preparation method of the compound quaternary ammonium salt disinfectant provided by the embodiment comprises the following steps: adding 8 wt% of didecyl dimethyl ammonium bromide, 8 wt% of ethylene base (didodecyl dimethyl ammonium bromide), 3 wt% of benzalkonium bromide, 0.8 wt% of disodium edetate, 0.3 wt% of hydroxyethylidene diphosphonic acid, 3 wt% of dodecyl dimethyl betaine, 2 wt% of cocamidopropyl ammonium oxide, 1.1 wt% of benzotriazole, 3 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the mixture is fully dissolved, adding a potassium carbonate solution to adjust the pH of the mixed solution in the reaction kettle to be 8-10, preparing the compound quaternary ammonium salt disinfectant, and filling for later use.
When the compound quaternary ammonium salt disinfectant provided in example 6 is used, the following components are added: ethylene glycol: isopropyl alcohol: preparing a low-temperature synergistic solvent from calcium chloride in a mass ratio of 50:20:5:25, diluting the compound quaternary ammonium salt disinfectant and the low-temperature synergistic solvent in a mass ratio of 1:600, and then using the disinfectant for wiping or spraying the surfaces of environmental objects for disinfection. The diluted disinfectant is still in a liquid state after being placed in a low-temperature freezer with the temperature of-40 ℃ for 10 hours, and the phenomenon of icing and crystallization is avoided.
The compound quaternary ammonium salt disinfectant provided by the embodiments 1-6 is stored at 54 ℃ for 14 days, the reduction rate of the effective sterilization components is less than or equal to 10 percent, the technical requirements of the one-year storage period are met, and other technical indexes meet the regulations of GB 14930.1-2015 and QB/T4314-2012.
Comparative example 1:
the benzotriazole and the polyglyceryl ether in the example 3 are removed and replaced by the same amount of water, and other components and the content of the components are not changed.
After example 3 and comparative example 1 were diluted with water at a mass ratio of 1:600, respectively, the biocidal experiments were conducted according to "disinfection technical specification" 2002 edition: namely, the 5min suspension method is used for respectively carrying out killing experiments on escherichia coli, staphylococcus aureus and candida albicans, other experimental conditions are the same, and the experimental results are shown in the table 1:
TABLE 1 results of the microbial kill experiments
The experimental data in table 1 show that the compound quaternary ammonium salt disinfectant provided in embodiment 3 of the present invention still has a killing effect on three microorganisms in the surface after being diluted 600 times with water, while the comparative example 1 (where benzotriazole and polyglyceryl ether are not added) has an unqualified microorganism killing effect, so that the benzotriazole component and polyglyceryl ether component in the compound quaternary ammonium salt disinfectant of the present invention have a synergistic bactericidal effect in a disinfection system, so that the compound quaternary ammonium salt disinfectant can still realize an efficient sterilization function at a low concentration.
Comparative example 2:
the polyglyceryl ether component of example 2 was removed and replaced with an equal amount of water, and the other components and their contents were unchanged.
After example 2 and comparative example 2 were diluted with water at a mass ratio of 1:600, metal corrosion tests were conducted according to "specification for disinfection" 2002, and the corrosion rate and corrosion grade of metallic aluminum were compared, and the results are shown in table 2:
TABLE 2 Metal corrosiveness data
| Name (R) | Class of metals | Corrosion rate (mm/year) | Corrosion grade |
| Example 2 | Aluminium | 0.0042 | Substantially free of corrosion |
| Comparative example 2 | Aluminium | 0.0186 | Slight corrosion |
As can be seen from the experimental data in Table 2, the example 2 added with the polyglyceryl ether component has no corrosion to the metallic aluminum basically after being diluted, and the comparative example 2 has slight corrosion to the metallic aluminum after being diluted, so that the polyglyceryl ether (the multi-effect moisturizer such as the hand cream moisturizer) has corrosion-retarding effect and can be used as a corrosion inhibitor when being added into the quaternary ammonium salt disinfectant. The compound quaternary ammonium salt disinfectant containing the polyglyceryl ether component has a corrosion inhibition effect on metal aluminum, and the slow release principle is inferred as follows: the moisture-keeping film-forming effect of the polyglyceryl ether can prevent oxygen and halogen ions in quaternary ammonium salt from entering the surface of the metal aluminum, thereby realizing corrosion inhibition protection on the metal aluminum and being used for sterilizing and disinfecting the surface of an aluminum product.
In conclusion, the compound quaternary ammonium salt disinfectant provided by the invention has the advantages of low ecological toxicity, good environmental compatibility, easiness in storage and long service cycle; the compound quaternary ammonium salt disinfectant can be prepared by compounding the existing quaternary ammonium salt disinfectant, and the preparation process is simple; the added benzotriazole component and polyglycerol ether component have the effect of synergistic sterilization, so that the compound quaternary ammonium salt disinfectant can still realize the function of efficient sterilization under the low concentration of 600 times of dilution; in addition, the compound quaternary ammonium salt disinfectant added with the polyglyceryl ether component has no corrosion to metal aluminum after being diluted, and can be used for sterilizing and disinfecting the surface of an aluminum product.
It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and that those skilled in the art will be able to design alternative embodiments without departing from the scope of the appended claims. The present embodiments are, therefore, to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. In the claims, the word "comprising" does not exclude the presence of data or steps not listed in a claim.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (12)
1. A compound quaternary ammonium salt disinfectant comprises 16 wt% -20 wt% of quaternary ammonium salt bactericide, 0.5 wt% -3 wt% of metal ion chelating agent, 0.5 wt% -10 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the PH of mixed liquor to 8-10, and is characterized in that: the compound quaternary ammonium salt disinfectant also comprises 0.5-1.5 wt% of benzotriazole and 1-5 wt% of polyglycerol ether, wherein the molar ratio of ethoxy to glyceryl in the polyglycerol ether is 26:1, and the balance is water.
2. The compound quaternary ammonium salt disinfectant as set forth in claim 1, wherein: the quaternary ammonium salt bactericide at least comprises one of benzalkonium chloride, benzalkonium bromide, didecyl dimethyl ammonium chloride, didecyl dimethyl ammonium bromide, decyl methyl hydroxyethyl/hydroxypropyl ammonium chloride, cetyl trimethyl ammonium bromide and ethylene (didodecyl dimethyl ammonium bromide).
3. The compound quaternary ammonium salt disinfectant as set forth in claim 1, wherein: the metal ion chelating agent at least comprises one of ethylene diamine tetraacetic acid and sodium salt thereof, nitrilotriacetic acid and sodium salt thereof, sodium gluconate, sodium citrate, hydroxyethylidene diphosphonic acid and sodium salt thereof, ethylene diamine tetramethylene phosphonic acid and sodium salt thereof, 2-phosphate-1, 2, 4-butane tricarboxylate, 2-hydroxyphosphonoacetic acid and sodium salt thereof.
4. The compound quaternary ammonium salt disinfectant as set forth in claim 1, wherein: the water-soluble amphoteric surfactant at least comprises one of cocamidopropyl betaine, dodecyl dimethyl betaine, dodecyl propyl betaine, cocamidopropyl ammonium oxide, dodecyl propyl ammonium oxide and dodecyl dimethyl amine oxide.
5. The compound quaternary ammonium salt disinfectant as set forth in claim 1, wherein: the strong alkali solution at least comprises one of sodium hydroxide aqueous solution, potassium hydroxide aqueous solution, sodium carbonate aqueous solution and potassium carbonate aqueous solution.
6. A compound quaternary ammonium salt disinfectant is characterized in that: comprises 17 wt% -19 wt% of quaternary ammonium salt, 1 wt% -2 wt% of metal ion chelating agent, 3 wt% -7 wt% of water-soluble amphoteric surfactant and strong alkali liquor for adjusting the pH of the mixed liquor to 8-10; the compound quaternary ammonium salt disinfectant also comprises 0.8-1.2 wt% of benzotriazole, 2-4 wt% of polyglycerol ether and the balance of water.
7. The method for preparing the compound quaternary ammonium salt disinfectant as set forth in any one of claims 1 to 5, characterized in that: adding 16-20 wt% of quaternary ammonium salt bactericide, 0.5-3 wt% of metal ion chelating agent, 0.5-10 wt% of water-soluble amphoteric surfactant, 0.5-1.5 wt% of benzotriazole, 1-5 wt% of polyglycerol ether and water into a reaction kettle, controlling the temperature of the reaction kettle to be 20-35 ℃, uniformly stirring until the mixture is fully dissolved, and adding strong alkali liquor to adjust the pH of the mixed liquor in the reaction kettle to 8-10 to obtain the compound quaternary ammonium salt disinfectant.
8. The method of using the compound quaternary ammonium salt disinfectant as set forth in any one of claims 1 to 5, characterized in that: the compound quaternary ammonium salt disinfectant is diluted by water for use, and the dilution mass ratio is 1: 50-600.
9. The method of using the compound quaternary ammonium salt disinfectant as set forth in any one of claims 1 to 5, characterized in that: diluting the compound quaternary ammonium salt disinfectant with a mixed diluent prepared from water and a water-soluble alcohol solvent, wherein the dilution mass ratio of the compound quaternary ammonium salt disinfectant to the mixed diluent is 1:50-600, and the volume ratio of water to the water-soluble alcohol solvent in the mixed diluent is 1: 1-9: 1.
10. the method of using the compound quaternary ammonium salt disinfectant as set forth in any one of claims 1 to 5, characterized in that: diluting the compound quaternary ammonium salt disinfectant with a low-temperature synergistic solvent for use, wherein the dilution mass ratio is 1: 50-600; the low-temperature synergistic solvent comprises 25-30 wt% of halogenated salt, 25-30 wt% of water-soluble alcohol solvent and the balance of water.
11. The method of using a compound quaternary ammonium salt disinfectant as set forth in claim 10, wherein: the halogenated salt at least comprises one of sodium chloride and calcium chloride.
12. The method of using the compound quaternary ammonium salt disinfectant as set forth in claim 9 or 10, characterized in that: the water-soluble alcohol solvent at least comprises one of methanol, ethanol, ethylene glycol, propylene glycol, isopropanol, 1, 3-butanediol, glycerol, diethylene glycol and triethylene glycol.
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