CN112782415B

CN112782415B - Test pre-processing device, medical equipment and testing method

Info

Publication number: CN112782415B
Application number: CN202011553652.XA
Authority: CN
Inventors: 黄公安; 徐吉; 李根乾
Original assignee: Xingtong Medical Technology Suzhou Co ltd
Current assignee: Xingtong Medical Technology Suzhou Co ltd
Priority date: 2020-12-24
Filing date: 2020-12-24
Publication date: 2025-01-10
Anticipated expiration: 2040-12-24
Also published as: CN112782415A

Abstract

The invention discloses a test pretreatment device, medical equipment and a detection method, wherein the test pretreatment device comprises a tray, a tray fixing jig, a material supply mechanism, a test solution storage mechanism and an injection mechanism, wherein the tray is provided with at least one limiting groove, the tray fixing jig is provided with a structure for installing and fixing the tray, the material supply mechanism is provided with a structure for storing materials in batches and transferring the materials onto the tray one by one, the test solution storage mechanism is provided with a group of containers, and the injection mechanism is provided with a structure capable of extending into a groove of any container for absorbing liquid and injecting the liquid into the material on the tray. According to the scheme, the tray is arranged to install the reagent strips, batch materials are stored through the material supply mechanism, the stored materials are transferred to the tray to meet the test requirement, the injection mechanism is combined to automatically inject the test liquid in the container into the grooves of the reagent strips on the tray, the test requirement of a large number of items can be met, equipment conditions are created for the automatic implementation of various tests, and the detection efficiency is improved.

Description

Pretreatment device for test, medical equipment and detection method

Technical Field

The invention relates to the field of medical equipment, in particular to a pretreatment device for testing, medical equipment and a detection method.

Background

The cycle-enhanced fluorescent immune reaction is a high-sensitivity fluorescent immune reaction, which enhances the intensity of a fluorescent signal by a certain method, thereby enabling detection of a low concentration target.

The reaction and corresponding detection are achieved by automated equipment, and in automated detection, the reagent strip is the material required for testing, and is provided with

(1) Reading the well, wherein fluorescent signals on the probe are read;

(2) Washing the hole, and finishing washing of interference substances, redundant signal antibodies and redundant fluorescent signals in the sample on the probe in the hole;

(3) A dry reagent well in which a dry reagent for sample treatment, signal antibody and fluorescent signal is present, and which reacts with the probe after dissolution;

(4) And a probe storage hole in which the probe is stored and locked with a protective cover.

In testing, the reagent strips need to be pre-treated to facilitate subsequent addition of test fluid for the reaction and testing of the supply.

In order to meet the test requirements of a large number of items, the automatic equipment needs to be capable of storing a plurality of reagent strips and automatically transferring and supplying the reagent strips;

secondly, the test solution can be automatically injected into different holes of the reagent strip.

Disclosure of Invention

The invention aims to solve the problems in the prior art and provides a pretreatment device for testing, medical equipment and a detection method.

The aim of the invention is achieved by the following technical scheme:

A test pretreatment device comprises

The tray is provided with at least one limit groove;

The tray fixing jig is provided with a structure for installing and fixing the tray;

the material supply mechanism is provided with a structure for storing materials in batches and transferring the materials onto a tray one by one;

a test liquid storage mechanism having a set of containers;

the injection mechanism is provided with a structure which can extend into a groove of any material which is absorbed in the container and injected onto the tray.

Preferably, the tray has at least 5 side-by-side limit slots.

Preferably, the material supply mechanism comprises

A material storage device having a plurality of layers of openable drawers;

The multifunctional manipulator is provided with an adsorption device for adsorbing the drawer and a first clamping mechanism for clamping materials in the drawer;

and the moving mechanism drives the multifunctional manipulator to move.

Preferably, the multifunctional manipulator further comprises a code reader, wherein the code reader is obliquely arranged, and the lens of the code reader faces downwards and faces the material storage device.

Preferably, the injection mechanism at least comprises a vertical suction nozzle connecting pipe and a suction injection mechanism connected with the upper end of the suction nozzle connecting pipe, the suction nozzle connecting pipe is connected with a mechanism for driving the suction nozzle connecting pipe to move horizontally along a first horizontal direction Y and/or a second horizontal direction X and move along a vertical direction Z, and the suction injection mechanism and the suction nozzle connecting pipe synchronously move horizontally.

Preferably, the suction injection mechanism comprises a syringe connected with the suction nozzle connecting pipe and a mechanism for driving a piston rod of the syringe, and the suction nozzle is perpendicular to the syringe.

Preferably, the injection mechanism further comprises a blanking device and a suction nozzle automatic supply mechanism positioned beside the blanking device, the blanking device comprises a limiting plate which is positioned in the moving range of the suction nozzle connecting pipe and is perpendicular to the suction nozzle connecting pipe, at least one perforation is formed on the limiting plate, and the outer wall of the limiting plate keeps a distance from the wall of the perforation in the coaxial state of the suction nozzle connecting pipe and the perforation.

Preferably, the automatic nozzle supply mechanism comprises

The storage bin is provided with a storage space for storing the multi-layer stacked objects, and the bottom of the storage bin is provided with a feed opening;

The conveying jig is positioned below the storage bin for a certain distance and can move between a first horizontal position and a second horizontal position, wherein the first horizontal position corresponds to a feed opening of the storage bin;

the automatic blanking mechanism can move the objects stacked in multiple layers to the conveying jig at the first horizontal position one by one.

Preferably, the test pretreatment device further comprises a film opening mechanism, wherein the film opening mechanism comprises a row of film opening cones which are arranged along the extending direction of the limiting groove, the film opening cones are vertically arranged, and the film opening cones are connected with a mechanism for driving the film opening cones to synchronously move vertically and horizontally.

Preferably, the test pretreatment device further comprises

The cover opening mechanism at least comprises a first cover opening plate, the first cover opening plate is vertical and perpendicular to the limit groove, and the first cover opening plate is connected with a mechanism for driving the first cover opening plate to lift and translate;

the probe transfer mechanism is provided with a probe clamping jaw and a mechanism for driving the probe clamping jaw to lift and translate, and the probe transfer mechanism and the cover opening mechanism translate synchronously.

Preferably, the test pretreatment device comprises a horizontal compression bar, the extension direction of the compression bar is vertical to the limit groove and is connected with a mechanism for driving the compression bar to translate and lift, and the compression bar can translate to the position right above the limit groove.

Preferably, the test pretreatment device comprises

The tray positioning jig is provided with a limiting structure for positioning the tray;

The tray transfer mechanism has a structure for moving the tray between the tray fixing jig and the tray positioning jig.

Preferably, the test pretreatment device comprises

The blanking plate is vertically arranged and is vertical or parallel to the limit groove of the tray on the tray fixing jig;

the tray transfer mechanism comprises

The tray clamping jaw comprises two clamping rods which are equal in height and horizontally extend and an opening and closing driving device for driving the clamping rods to open and close, and the clamping rods are perpendicular to or parallel to the blanking plate;

the clamping jaw overturning mechanism is connected with the tray clamping jaw and drives the tray clamping jaw to rotate around a parallel shaft of the clamping rod;

and the moving mechanism drives the clamping turnover mechanism to translate and lift, and the clamping rods move between the upper position and the lower position of the blanking plate and move from the outer side of the blanking plate to correspond to the position of the blanking plate in the vertical direction.

Preferably, the lower end face of the blanking plate of the test pretreatment device is a group of planes with height differences.

Medical equipment comprises the test pretreatment device.

The detection method at least comprises the following steps:

S1, fixing a tray on a tray fixing jig;

s3, the material supply mechanism moves at least one material to a limit groove of the tray for limiting;

S5, the injection mechanism sucks liquid from the appointed container and injects the liquid into a groove of the material on the tray according to the metering.

Preferably, the S3 comprises

S31, an adsorption device on the multifunctional manipulator adsorbs the drawer and opens the drawer;

S32, a code reader on the multifunctional manipulator reads bar codes on materials in the drawer to determine the types, the quantity and the positions of the materials;

s33, the first clamping mechanism on the multifunctional manipulator clamps and moves out at least one material in the drawer and places the drawer in the limit groove of the tray.

Preferably, the device further comprises an S41 positioned between the S3 and the S5, and the protective film on the surface of the material on the tray is punctured by the film opening mechanism.

Preferably, the probe transfer mechanism further comprises an S42 located between the S3 and the S5, wherein the cover opening mechanism is used for opening the protective cover on the material and the probe transfer mechanism is used for taking out the probe from the material and placing the probe on the tray.

Preferably, the tray transfer mechanism further comprises an S43 located between the S3 and the S5, and the tray is moved from the tray fixing jig to the tray positioning jig through the tray transfer mechanism.

Preferably, the step S3 includes unloading the suction nozzle on the suction pipe connecting nozzle through the blanking device and moving the suction nozzle connecting pipe to the conveying jig of the second horizontal position to replace the suction nozzle before sucking different test liquids.

Preferably, the tray transfer mechanism turns the tray 180 degrees after the test is completed and moves the tray to the lower part of the blanking plate, the blanking plate applies a downward pressure to the materials in the tray until the materials fall from the limiting groove by lifting the tray, and the tray transfer mechanism turns the tray 180 degrees again and places the tray on the tray fixing jig after the blanking is completed.

The technical scheme of the invention has the advantages that:

According to the scheme, the tray is arranged to install the reagent strips, batch materials are stored through the material supply mechanism, the stored materials are transferred to the tray to meet the test requirement, the injection mechanism is combined to automatically inject the test liquid in the container into the grooves of the reagent strips on the tray, the test requirement of a large number of items can be met, equipment conditions are created for the automatic implementation of various tests, and the detection efficiency is improved.

According to the technical scheme, the material storage device is provided with the drawer with the plastic sucking box limiting groove, the reagent strips can be placed in the plastic sucking box and then inserted into the plastic sucking box limiting groove for storage, when the reagent strips are needed to be used, the drawer can be opened, so that the reagent strips can be conveniently taken out from the drawer for use by being matched with the automatic material taking structure, and when the plastic sucking box is inserted, the drawer is limited to be not opened by the first limiting mechanism, so that the difficulty of inserting the plastic sucking box can be effectively reduced, and the operability is improved. The storage device can be effectively matched with a multifunctional manipulator to realize the storage and transfer requirements of the reagent strips. Simultaneously through integrate on the manipulator have electromagnetic adsorption device, can be when getting the material, open the drawer through electromagnetic adsorption's mode to be convenient for follow-up getting the material through the first fixture on it, through setting up the sign indicating number ware of sweeping, can confirm effectively that the type of reagent strip in the drawer, quantity and position confirm, for the control of first fixture provides data support, greatly improved the integrated level of equipment, and make a plurality of parts can share a moving mechanism, can simplify the structure effectively.

The first stop gear of this scheme can be simultaneously a plurality of the opening of drawer is restricted to be favorable to simplifying limit structure, reduce the quantity of power supply, reduce equipment cost.

This scheme sets up second stop gear, can be to every the opening of drawer is prescribe a limit to, and can realize dual assurance with first stop gear cooperation, and simultaneously second stop gear can also realize the prescribing a limit to that the drawer was closed with the cooperation of the second lug on the drawer to can avoid the drawer to remove when follow-up uninstallation reagent strip and cause the problem of unable stable uninstallation. The second limiting mechanism can share one linear driving mechanism, so that the driving structure can be effectively simplified, and the equipment cost is reduced.

The first fixture of this scheme adopts motor drive, can adjust the switching size of clamping jaw as required in a flexible way to adapt to the centre gripping requirement of not unidimensional article, it is good to use the flexibility.

The multifunctional manipulator of this scheme is last further to integrate the mechanism of uncapping and can realize the automation of probe visor effectively and open to the mechanism of uncapping of this scheme can be with all opening the probe visor of all reagent strips on the tray through once operation, uncaps efficiently, and stability is good, is favorable to simplifying the structure, enriches the function of equipment. And can be fixed the reagent strip when uncapping through the depression bar to avoid uncapping the action to cause the not hard up of reagent strip, displacement, be favorable to guaranteeing the stability of follow-up operation. The probe clamping jaw with flexibly adjustable opening and closing size is further integrated, and the probe can be conveniently moved out of the probe storage hole on the tray after the cover is opened, so that convenience is brought to subsequent testing.

According to the scheme, the membrane on each hole of the reagent strip can be torn at one time by the membrane opening device with the plurality of membrane opening cones to realize membrane opening, so that basic conditions are created for the subsequent addition of test liquid, technical support is provided for the automatic realization, and the product functions are enriched.

According to the scheme, the suction nozzle connecting pipe is driven to move through the moving mechanism, and the suction nozzle connecting pipe is coaxial with the axis of the injector, so that the length of the whole automatic injection structure can be effectively shortened, and the whole height of equipment is reduced. The design of the suction injection mechanism, in particular the push-pull mechanism adopts motor drive and combines an electromagnetic valve, so that the single injection quantity can be conveniently controlled, and different test requirements can be flexibly met.

According to the scheme, through arranging the perforation on the limiting plate of the blanking device so that the suction nozzle connecting pipe inserted with the suction nozzle conveniently penetrates through the lower part of the perforation, then the top of the suction nozzle is located at the bottom of the limiting plate around the perforation through movement of the suction nozzle connecting pipe, and the suction nozzle connecting pipe are separated through ascending of the suction nozzle connecting pipe, so that basic conditions are provided for testing different projects for replacing the suction nozzle again.

The storage bin of this scheme can store a plurality of receiver, combines automatic feed mechanism can be effectively with the receiver of stacking in the storage bin separate one by one to on the transport tool is for carrying, combines the transport tool to carry a receiver in the storage bin outside to the storage bin for use to can greatly increase the supply of suction head, reduce the frequency of adding the receiver, be favorable to satisfying the requirement of big batch test.

The conveying jig of this scheme adopts slide conveying mechanism to make translation drive structure be located the outside, can conveniently carry out the equipment operation, reduce the processing and maintain the degree of difficulty. And the conveying jig can be effectively matched with the suction nozzle connecting pipe to realize automatic unloading of the material box, thereby being beneficial to improving the replacement efficiency of the material box.

The automatic blanking mechanism of this scheme adopts recess and gyro wheel cooperation to realize opening and closing of centre gripping arm, can guarantee switching precision and stability effectively.

This scheme is through setting up vertically flitch to through setting up the tray clamping jaw that can overturn, through tray clamping jaw centre gripping tray and make the tray upset 180, make the reagent strip orientation, can make the reagent strip remove to the flitch through the lift of tray afterwards, along with the continuous rising of tray, the flitch provides down force to the reagent strip and makes it withdraw from the tray, and accomplish the unloading under the dead weight.

The adoption of the blanking plate of this scheme and the vertically state of clamping lever can realize the unloading of a plurality of reagent strips in the unloading action of once effectively, can be very big improvement unloading efficiency.

The bottom of the blanking plate adopts the plane structure with different height differences, and the bottom surface of the blanking plate can be contacted with reagent strips at different positions in batches, so that the required blanking pressure is reduced, and the smooth shape and the stability of blanking are improved.

Drawings

Fig. 1 is a perspective view of a tray of the present invention;

FIG. 2 is a top view of the tray of the present invention secured to a tray securing jig;

FIG. 3 is a perspective view of the present invention (with the outer enclosure of the machine hidden);

FIG. 4 is a perspective view of the material supply mechanism of the present invention;

FIG. 5 is a first perspective view of the material storage device of the present invention;

FIG. 6 is a second perspective view of the material storage device of the present invention;

FIG. 7 is an inner end view of the material storage device of the present invention;

FIG. 8 is an enlarged view of area A of FIG. 6;

FIG. 9 is an enlarged view of area B of FIG. 7;

FIG. 10 is a side view of the material storage device of the present invention;

FIG. 11 is a perspective view of the multi-function manipulator of the present invention;

FIG. 12 is a front view of the multi-function manipulator of the present invention;

FIG. 13 is a bottom view of the multi-function manipulator of the present invention;

FIG. 14 is an enlarged view of region C of FIG. 12;

fig. 15 is a perspective view of the multifunctional manipulator of the present invention provided on a structure for driving the elevation thereof;

FIG. 16 is a perspective view of a first perspective of the multi-function manipulator of the present invention disposed on a structure for driving the elevation and translation thereof;

FIG. 17 is a second perspective view of the multi-function manipulator of the present invention disposed on a structure for driving the elevation and translation thereof;

Fig. 18 is a perspective view of the cap opening mechanism and the probe transfer mechanism of the present invention;

Fig. 19 is a front view of fig. 18;

FIG. 20 is a cross-sectional view of the probe jaw of FIG. 18;

FIG. 21 is a schematic view of the positional relationship of the opening cone and tray of the present invention;

FIG. 22 is a top view of the tray, tray fixture, film opening mechanism and compression bar of the present invention;

FIG. 23 is a perspective view of the injection mechanism of the present invention;

FIG. 24 is an enlarged view of area D of FIG. 23;

FIG. 25 is a perspective view of the injection mechanism with the tripper of the present invention;

FIG. 26 is a top view of FIG. 25;

FIG. 27 is an enlarged view of area E of FIG. 26;

FIG. 28 is a perspective view of the automatic nozzle supply mechanism with the ejector of the present invention;

FIG. 29 is a perspective view of the automatic suction nozzle supply mechanism and the drive and transport jig of FIG. 28;

fig. 30 is a first perspective view of the automatic nozzle supply mechanism of the present invention;

FIG. 31 is a partial side elevational view of the feed side of the automatic nozzle supply mechanism of the present invention;

FIG. 32 is a perspective view of a storage bin gate of the automatic nozzle supply mechanism of the present invention;

fig. 33 is an enlarged view of region F in fig. 31;

Fig. 34 is a second perspective view of the automatic nozzle supply mechanism of the present invention;

FIG. 35 is a side view showing a part of the structure of the automatic suction nozzle supply mechanism of the present invention excluding the automatic blanking mechanism;

FIG. 36 is a perspective view of the pallet positioning jig, pallet transfer mechanism and blanking plate area of the present invention;

fig. 37 is an enlarged view of the area G in fig. 36;

FIG. 38 is a front view of the blanking plate of the present invention;

FIG. 39 is a perspective view of the pallet positioning fixture and automatic turret area of the present invention;

fig. 40 is a top view of fig. 39.

Detailed Description

The objects, advantages and features of the present invention are illustrated and explained by the following non-limiting description of preferred embodiments. These embodiments are only typical examples of the technical scheme of the invention, and all technical schemes formed by adopting equivalent substitution or equivalent transformation fall within the scope of the invention.

In the description of the embodiments, it should be noted that the positional or positional relationship indicated by the terms such as "center", "upper", "lower", "left", "right", "front", "rear", "vertical", "horizontal", "inner", "outer", etc. are based on the positional or positional relationship shown in the drawings, are merely for convenience of description and simplification of description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be configured and operated in the specific orientation, and thus are not to be construed as limiting the present invention. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In the description of the scheme, the direction approaching the operator is the near end, and the direction separating from the operator is the far end, with reference to the operator.

The pretreatment device for testing disclosed in the present invention is described below with reference to the accompanying drawings, and can be used for various treatments required for testing the reagent strips before the fluorescent immune reaction is circularly enhanced, and of course, can also be used for other tests. As shown in fig. 1, it includes a tray 200, and the tray 200 is used to limit the position of the reagent strips (not shown in the drawing) so as to perform various operations on the reagent strips.

Specifically, as shown in fig. 1, the tray 200 includes a main body 220, at least one limiting groove 210 is formed on the main body 220, preferably, the limiting grooves 210 are 10 and arranged in parallel, each limiting groove 210 includes two parallel and spaced vertically arranged limiting surfaces 211, a bottom surface 212 located at the lower end of each limiting surface 211 is arranged between each limiting surface 211, one end outer side of each limiting surface 211 is provided with a distal limiting rod 213 connected with each limiting surface, the other end of each limiting surface 211 is connected with a proximal limiting rod 214 perpendicular to each limiting rod 213, the top surface of each distal limiting rod 213 is higher than the bottom surface 212, and a gap 215 between each distal limiting rod 213 and each limiting surface 212 is used for removing reagent strips from the limiting groove 210.

As shown in fig. 1, the end surface of the distal end limiting rod 213 facing the proximal end limiting rod 214 is an inclined surface and is provided with a locking groove 216, the locking groove 216 is used for limiting the reagent strip in the limiting groove 210, the locking groove 216 is an arc-shaped through groove concavely arranged at the side wall, and two ends of the arc-shaped through groove extend to the top surface and the bottom surface of the proximal end limiting rod 213.

As shown in figure 1, the width of the top edge of the cambered surface of the cambered through groove is smaller than the width of the bottom edge, and the distance from the midpoint of the top edge of the cambered surface to the proximal limiting rod is smaller than the distance from the midpoint of the bottom edge of the cambered surface to the proximal limiting rod, so that the change of the total length of the reagent strip can be adapted, and the control of the force required by pressing the reagent strip into the carrier is facilitated.

As shown in fig. 1, the main body 220 is formed with a probe receiving hole 230 matching each of the limit grooves, and the probe receiving hole 230 is specifically disposed on the distal limit lever 214, so that it can be used for temporary storage of probes on a reagent strip.

As shown in fig. 1 and fig. 2, the tray 200 is fixed on the tray fixing jig 300, and the limiting groove 210 thereon extends along the second horizontal direction X, the tray fixing jig 300 is fixed on a platen 4000, as shown in fig. 22, the tray fixing jig 300 includes a pallet positioning plate 310, through holes 311 located at two sides of the tray 200 are provided on the positioning plate 310, an L-shaped fixing plate 320 is movably provided in each through hole 311, the L-shaped fixing plate 320 can drive a fixing release driving mechanism 330 that reciprocates along a direction perpendicular to the side of the tray 200, and after the two L-shaped fixing plates 320 move in opposite directions, the two L-shaped fixing plates 320 can be pressed at two sides of the tray to fix the tray 200 on the positioning plate 310, and when the L-shaped fixing plates 320 move in opposite directions, the fixing of the tray 200 can be released. Further, the fixing and releasing mechanism 330 may be further connected to a lifting driving device (not shown in the drawings) for driving the lifting.

After the tray 200 is fixed on the tray fixing jig 300, during testing, reagent strips are required to be placed in the limit grooves of the tray 200 for testing, so as shown in fig. 3 and 4, a material supply mechanism 1000 is provided at the side of the tray fixing jig 300, and the material supply mechanism 1000 has a structure for storing materials in batches and transferring the materials onto the tray one by one.

In particular, as shown in fig. 4, the material supply mechanism 1000 includes a material storage device having a plurality of openable and closable drawers;

and the moving mechanism drives the multifunctional manipulator to move.

As shown in fig. 3, the material storage device is also disposed on the platen 4000 and is located at the left side of the tray fixing jig 300, as shown in fig. 5, and includes an outer frame 1, where the outer frame 1 is a rectangular frame formed by combining four side plates, at least one drawer 2 is disposed in the outer frame 1, the drawer 2 may translate to the outer side of the outer frame 1, and the drawer 2 is preferably a sliding rail type drawer, and its specific structure is a known technology and will not be repeated herein. The drawer 2 is provided with at least one plastic uptake box limit groove 21, the plastic uptake box limit groove 21 is used for limiting the plastic uptake box, the plastic uptake box is used for storing reagent strips, the plastic uptake box limit groove 21 comprises a bottom plate, side plates positioned at two sides of the bottom plate and an inner end plate positioned at the inner end of the bottom plate, one end (far away from one end of the tray fixing jig) of the plastic uptake box limit groove 21 is open and faces outwards and is used for inserting the plastic uptake box (not shown in the drawing) into the plastic uptake box limit groove 21 for storing.

In practical testing, there are often large-scale and multi-category testing requirements, so as shown in fig. 5-7, the number of drawers 2 is multiple, preferably at least three, more particularly 10, and three side-by-side blister box limiting slots 21 are formed on each drawer 2, so that the storage device can store 30 blister boxes at the same time, and each blister box can be provided with multiple reagent strips, thereby greatly improving the storage capability.

In general, the width of each of the plastic box limiting grooves 21 is equal to the width of the plastic box to ensure the stability of limiting, but this is inconvenient for placing the plastic box into the plastic box limiting groove 21, so, as shown in fig. 8, the outer frame 1 is provided with a guiding groove 3 connected with the inlet end of each of the plastic box limiting grooves, the guiding groove 3 includes two guiding blocks located at two sides of the inlet end of the agent strip tray limiting groove 21, and a wedge-shaped groove space with a large opening end and a small inner end is formed between the two guiding blocks. An indicator lamp 4 is arranged at the inlet of each guide groove 3, and the indicator lamp 4 is used for indicating whether a plastic suction box exists in the corresponding plastic suction box limiting groove 21.

Although the addition of the guide groove 3 can reduce the difficulty of inserting the suction box, the drawer 2 is opened by pushing force when inserting the suction box into each of the suction box limiting grooves 21, which is obviously disadvantageous for the operation of inserting the suction box. Therefore, as shown in fig. 5 and fig. 7, the first limiting mechanism 5 with a power source is further disposed on the outer frame 1 to at least limit the opening of the drawer 2, so that the drawer can be effectively prevented from being opened when the plastic box is inserted into the plastic box limiting groove 21, and the first limiting mechanism 5 automatically releases the limitation of the opening motion of the drawer 2 when the plastic box is placed and needs to be opened subsequently, so that the drawer with the plastic box can be opened for corresponding operation.

Since the number of drawers 2 is plural, it is necessary to restrict the opening of each drawer 2 when the plastic suction box is inserted, and in this embodiment, the opening of all the drawers 2 is restricted by the first stopper mechanism 5. The specific structure of the first limiting mechanism 5 will be described in detail below, as shown in fig. 5, 7 and 9, the first limiting mechanism includes a power source 51 capable of generating a linear movement in a vertical direction Z, the power source 51 may be an air cylinder or a hydraulic cylinder or a linear movement device driven by a motor, the power source 51 is connected to a vertical rod 52 driven by the power source to move at a first height and a second height, a blocking block 54 corresponding to each of the lugs 53 on the side of the drawer 2 is formed on the side of the vertical rod 52, at the first height, the blocking block 54 is located in front of the lugs 53 of the drawer 2 in a closed state (defining a position where the drawer passes first after and before during the opening of the drawer 2), that is, the blocking block 54 is located on a movement path when the lugs 53 are opened, so that the lugs 53 cannot be opened continuously, and at the second height, the blocking block 54 and the lugs 53 are dislocated in the vertical direction, so that the blocking block 54 does not generate blocking of the movement of the lugs 53.

In order to ensure the movement stability of the vertical rod 52, as shown in fig. 5, a guide post (not shown in the drawing) is arranged on the bracket, the guide post is inserted into a waist-shaped hole extending in the vertical direction on the vertical rod 52, as shown in fig. 1, the vertical rod 52 is connected with a cross rod 55 perpendicular to the vertical rod, the cross rod 55 is connected with the power source 51, two guide sleeves 56 are arranged on the cross rod 55, a guide shaft 57 extending in the vertical direction is inserted into the two guide sleeves 56 respectively, and the guide shaft 57 is fixed on the outer frame 1.

Further, the outer frame 1 is provided with second limiting mechanisms corresponding to the number of the drawers 2, each second limiting mechanism can at least limit the corresponding drawers 2 to open, specifically, as shown in fig. 10, the second limiting mechanisms include limiting pins 6 located at the side parts of each drawer 2, the limiting pins 6 can be axially moved along and vertically arranged on one side plate 11 of the outer frame, through holes 12 for the limiting pins 6 to pass through are arranged on the side plate 11, a shaft sleeve (not shown in the drawing) can be arranged on the outer side of the side plate 11, the limiting pins 6 sequentially penetrate into the shaft sleeve and the side plate 11, and the limiting pins 6 are connected with a linear driving device (not shown in the drawing) for driving the limiting pins to move, for example, an air cylinder, in a first state, the linear driving device drives the limiting pins 6 to extend into the outer frame 1 and is located in front of the protruding blocks 53 on the drawers 2 in a closed state, and in a second state, the limiting pins 6 can be effectively located on the outer side of the protruding blocks 53, and thus the limiting pins 53 are driven by the linear driving device.

Each of the second limit mechanisms may have a separate linear driving device, but this requires a plurality of linear driving devices, which is disadvantageous in terms of structural simplicity and cost reduction, so that in a preferred embodiment, as shown in fig. 10, a group of the limit pins 6 is driven to move axially along the same by one linear driving device, and at this time, the linear driving devices need to be moved vertically to each of the limit pins 6 and connected to the limit pins 6, and then the limit pins 6 are driven to move axially along the same, and at this time, the linear driving devices may be automatically and rapidly connected to and disconnected from the limit pins 6 by a snap-on structure such as a clamping jaw or an electromagnet.

The lifting drive mechanism for driving the linear drive device to lift can be designed according to the requirement, for example, a non-sensing cylinder or a hydraulic cylinder or an electric push rod extending along the vertical direction Z can be used for driving the linear drive device to lift. In a preferred embodiment, as shown in fig. 10, the lifting driving mechanism 7 includes a motor 71 fixed on the side of the frame, the output shaft of the motor 71 is coaxially connected with a driving wheel 72, the driving wheel 72 is lower than the drawer at the lowest layer, the driving wheel 72 is connected with a driven wheel 74 through a driving belt 73, the driven wheel 74 is higher than the drawer at the highest layer, the driving belt 73 is connected with a connecting plate (not shown in the drawing), the connecting plate is slidably arranged on a guide rail (not shown in the drawing) extending along the vertical direction Z through a sliding block 75, and the linear driving device is connected with the connecting plate, so that the forward and backward rotation of the motor drives the belt to rotate forward and backward, thereby realizing the lifting of the connecting plate, and further driving the linear driving device to lift to the limiting pins 6 at different positions for connection.

While each of the limiting pins 6 also cooperates with a second projection (not shown) on the side of the drawer 2 to limit the closing of the drawer, i.e. when the drawer 2 is opened, the second projection is located in front of the limiting pin 6 in the second state, so that the limiting pin 6 limits the second projection from closing the drawer 2. Of course, in other embodiments, the drawer may be prevented from closing by the first stop block 54 cooperating with the second tab.

Further, an openable door (not shown in the figure) is further disposed on the outer frame 1, at least covering all the drawers, the door and the drawer in an opened state are located at opposite sides of the outer frame, the openable door is used for being opened when reagent strips are added, after the reagent strips are placed in the plastic suction box limiting groove 21, the door is closed, and the door can be an automatic door or a manual door, and the specific structure of the door is a known technology and is not described herein.

When the subsequent test is performed, the drawers 2 need to be opened to take out the reagent strips therein, and for convenience, the drawers 2 are automatically opened, a part which can be magnetically attracted is arranged at one end of each drawer 2 facing the opening direction, the connection of the opening mechanism and the drawers 2 can be realized through magnetic attraction, and then the drawers 2 are opened by applying a pulling force to the drawers 2.

Specifically, any drawer 2 is opened and taken out by the multifunctional manipulator, as shown in fig. 4 and 11, the multifunctional manipulator moves inside the material storage device (towards one side of the tray fixing jig), and includes a mounting frame 8, and the specific structure of the mounting frame 8 may be that of the mounting frame 8, according to the need, in this embodiment, the mounting frame 8 includes at least a flat plate 81, and a first side of the flat plate 81 is provided with a first mounting member 82, and a second side opposite to the first side is provided with a second mounting member 83.

As shown in fig. 11, the first mounting member 82 is provided with an electromagnetic adsorption device 9, where the electromagnetic adsorption device 9 is a device that is electrified to generate magnetic force, for example, an electromagnet, an electromagnetic chuck, etc., and the specific structure thereof is a known technology and will not be described herein. The adsorption end of the electromagnetic adsorption device 9 faces outwards, and when the electromagnetic adsorption device is in operation, objects can be adsorbed and driven to move by magnetic force generated by the electromagnetic adsorption device 9.

As shown in fig. 11, the flat plate 81 is provided with a first clamping mechanism 20, and the first clamping mechanism 20 is located at the inner side of the electromagnetic adsorption device. As shown in fig. 12 and 13, the first clamping mechanism 20 includes two opposite jaw bodies 201, and the clamping portions 2011 of the two jaw bodies 201 are located below the first mounting member 82, so as to avoid interference during clamping, and the two jaw bodies 201 are connected to a driving mechanism for driving the two jaw bodies to move, where the driving mechanism may be a jaw cylinder, for example. In a preferred embodiment, the driving mechanism includes a first motor 202 disposed on the flat plate 81, a motor shaft of the first motor 202 vertically penetrates through the flat plate 81 and is coaxially connected with a driving gear 203 disposed below the flat plate 81, the driving gear 203 is meshed with teeth on two moving blocks 204, the two moving blocks 204 are disposed on two opposite sides of the driving gear 203 and are movably disposed on a guide rail 206 extending along a first horizontal direction Y through a sliding block 205, and one of the claw bodies 201 is fixed on each sliding block 205, so that when the first motor 202 is started, the driving gear 203 drives the two moving blocks 204 to move reversely, thereby opening and closing the two claw bodies 201.

When the first clamping mechanism 20 is used for clamping, information such as the position and the type of the object to be clamped needs to be determined, therefore, as shown in fig. 11, the code reader 10 is further arranged on the mounting frame 8, the code reader 10 is specifically arranged on the second mounting member 83 through a connecting member, and is obliquely arranged above the electromagnetic adsorption device 9, and the lens of the code reader is downward and faces the material storage device.

As shown in fig. 11, the mounting frame 8 is further provided with a second clamping mechanism 30, the opening and closing direction of the second clamping mechanism 30 is perpendicular to the opening and closing direction of the first clamping mechanism 20, and the lower end of the claw body 301 of the second clamping mechanism 30 is higher than the lower end of the claw body 201 of the first clamping mechanism 20.

As shown in fig. 14, the two claw bodies 301, 302 of the second clamping mechanism 30 may be driven to open and close by one cylinder, and in a more preferred embodiment, the claw body 301 is horizontally fixed and close to the first clamping mechanism 20, the other claw body 302 may translate relative to the claw body 301, and the claw body 302 may reciprocate along the second horizontal direction X (perpendicular to the first horizontal direction Y) to adjust the distance between the claw body 301 and the claw body. The claw body 302 is driven to move by a cylinder 303, the cylinder shaft of the cylinder 303 extends along the second horizontal direction Y and is connected to the claw body 302 through a transmission member 305, and the transmission member 305 is slidably arranged on a guide rail 306 extending along the second horizontal direction X.

The specific structure of the two claw bodies 301 and 302 may be designed according to the outline of the contact portion with the article, in a preferred embodiment, as shown in fig. 14, a square notch 3011 is formed on the claw body 301 at the right lower corner position of the claw body, the claw body 302 includes a clamping portion 3021 corresponding to the notch 3011, the end of the clamping portion 3021 is slightly higher than the end of the notch 3011, meanwhile, the end face of the clamping portion 3021 facing the claw body 301 is formed with a clamping notch 3022, a limiting rod 3033 is vertically arranged at the upper end of the clamping portion, and the minimum distance between the two claw bodies 301 and 302 is defined by the length of the limiting rod 3033.

In addition, in order to avoid interference between the second clamping mechanism 30 and the article during use, as shown in fig. 11, the second clamping mechanism 30 is connected to a first driving mechanism 304 that drives the second clamping mechanism to reciprocate along a vertical direction Z, the first driving mechanism 304 includes a second cylinder 3041, a cylinder shaft of the second cylinder 3041 extends along the vertical direction Z, the cylinder shaft of the second cylinder 3041 is connected to a lifting plate 3042, the lifting plate 3042 is slidably disposed on a longitudinal rail (not shown in the drawing) on a vertical plate of the second mounting member 83, and the cylinder 303 and the rail 305 are fixed on the lifting plate 3042.

The multifunctional manipulator is driven by a moving mechanism to move so as to realize the adjustment of the position of the multifunctional manipulator, so as to realize the opening and closing of drawers at different positions and the grabbing and moving of test strips at different positions of the drawers to the upper part of a tray, as shown in fig. 15, the moving mechanism comprises a stand 40, the mounting frame 8 is reciprocally movably arranged at the side part (left side) of the stand 40 along the vertical direction Z, specifically, the mounting frame 8 is slidably arranged on a longitudinal rail 401 extending along the vertical direction Z on the stand 40 through a sliding block, and meanwhile, a second driving mechanism 50 for driving the mounting frame 8 to move along the vertical direction is arranged on the stand 40. The second driving mechanism 50 includes a lifting driving motor 501, the lifting driving motor 501 is fixed at the top of the stand 40 and the motor shaft thereof extends along the first horizontal direction Y, the motor shaft is coaxially connected with a first driving wheel 502, the first driving wheel 502 is connected with a second driving wheel 504 through a synchronous belt 503, the second driving wheel 504 is rotatably disposed at the bottom of the stand 40, a clamping member 505 is disposed on the synchronous belt 503, and the clamping member 505 is disposed on the second mounting member 83 of the mounting frame 8.

As shown in fig. 16 and 17, the stand 40 is connected to a horizontal moving mechanism 100 for driving the stand 40 to move along a first horizontal direction Y and a second horizontal direction X, the horizontal moving mechanism 100 may be of various known structures, in a preferred embodiment, the horizontal moving mechanism includes a first translational driving mechanism 110 and a second translational driving mechanism 120, the first translational driving mechanism 110 includes a moving frame 116, one end of the moving frame 116 is provided with a first translational motor 111, a motor shaft of the first translational motor 111 is coaxially connected to a synchronous pulley 112, the synchronous pulley 112 is connected to a driven synchronous pulley 114 through a synchronous belt 113, the driven synchronous pulley 114 is rotatably disposed at the other end of the moving frame 116, a clamping block 115 is fixed on the synchronous belt 113, the clamping block 115 is fixed on the stand 40, and the stand 40 is slidably disposed on a horizontal rail extending along the first horizontal direction Y through a sliding block 117. The second translation driving mechanism 120 is similar to the first translation driving mechanism 110 in structure, and also adopts a motor, a synchronizing wheel, a synchronous belt, a clamping block, a guide rail, etc. to implement the translation of the first translation driving mechanism 110, which is not described herein.

After the reagent strips in the material storage device are transferred to the tray 200 by the multifunctional manipulator, a protective cover for protecting the probes on the reagent strips needs to be opened for subsequent operation.

As shown in fig. 18, the stand 40 is further provided with a cover opening mechanism 80, the cover opening mechanism 80 is used for opening a cover body on the reagent strip, the cover opening mechanism 80 includes a first cover opening plate 801, and the first cover opening plate 801 is connected with a fourth driving mechanism 90 for driving the first cover opening plate 801 to lift.

The lower portion of the first cover plate 801 includes a set of equidistant cover push rods 802, preferably 10 cover push rods 802, so that the covers on multiple reagent strips can be opened simultaneously.

Meanwhile, a second opening cover plate 803 is arranged on the inner side of the first opening cover plate 801 in a clearance mode, the lower end of the second opening cover plate 803 extends to the lower side of the first opening cover plate 801, a clearance between the second opening cover plate 803 and the first opening cover plate 801 is designed according to requirements, when the protective cover for the reagent strip is opened, the clearance between the second opening cover plate 803 and the first opening cover plate 801 is met, and when the cover opening push rod 802 is embedded into a clamping groove at the end portion of the protective cover, the second opening cover plate 803 is in contact with the end portion of the protective cover.

As shown in fig. 18 and 19, the first cover plate 801 and the second cover plate 803 are both connected to the fourth driving mechanism 90, the fourth driving mechanism 90 includes a vertical connection plate 901, two sides of the lower end of the vertical connection plate 901 are provided with the first cover plate 801 and the second cover plate 803, the upper end of the vertical connection plate 901 is connected to a connection block 902, the connection block 902 is connected to a movable nut of a second screw 903 and is slidably disposed on a second guide rail (not shown) extending along the vertical direction Z, a screw of the second screw 903 is rotatably disposed on the stand 40 and located on a side (right side) of the screw 703, and the screw of the second screw is connected to a motor 904 that drives the rotation of the second screw.

After opening the protective cover on the reagent strip, the probe needs to be removed from the probe well and placed in the probe receiving well on the tray for subsequent operation. Thus, as shown in fig. 18, the stand 40 is further provided with a probe jaw 60, the probe jaw 60 is located at two sides opposite to the stand 40 with respect to the mounting frame 8, and the probe jaw 60 is connected to a third driving mechanism 70 for driving the probe jaw 60 to reciprocate along the vertical direction Z, so that the mechanism for driving the probe jaw 60 to translate and the mechanism for driving the multifunctional manipulator to translate are a set of structures, although in other embodiments, a set of independent translating structures may be used for the probe jaw 60, which is obviously uneconomical.

In detail, as shown in fig. 20, the probe clamping jaw 60 includes a second motor 601, a motor shaft of the second motor 601 extends longitudinally and is eccentrically connected with a transmission member 602, a rotating member 603 capable of rotating relative to the transmission member 602 is coaxially connected with the transmission member 602, the rotating member 603 may be, for example, a bearing, the rotating member 603 is embedded in a mounting groove (not shown in the drawing) of the first clamping block 604, the aperture of the mounting groove is equivalent to the outer diameter of the rotating member 603, the first clamping block 604 is movably arranged on a guide rail 605 extending along the second horizontal direction X, the guide rail 605 is fixed on a fixed block 606, and the fixed block 606 is further provided with a second clamping block 607 which is matched with the first clamping block 604 to clamp.

When the probe clamping jaw works, the second motor 601 drives the transmission piece 602 to rotate and drives the rotation piece 603 to rotate, and the transmission piece 602 and the rotation piece 603 are eccentrically arranged, so that the rotation piece 603 revolves around the shaft of the rotation piece 602, and the first clamping block 604 is driven to reciprocate along the guide rail 605, so that the distance between the first clamping block 604 and the second clamping block 607 is changed, and the probe clamping jaw is opened and closed.

As shown in fig. 18, the fixed block 606 is connected to a third driving mechanism 70 for driving the third driving mechanism to reciprocate along a vertical direction Z, specifically, the third driving mechanism 70 includes a carrier plate 701 for fixing the fixed block 606, the carrier plate 701 is connected to a movable nut of a lead screw 703 through a transition block 702, a screw rod of the lead screw 703 extends along the vertical direction Z and two ends of the screw rod are rotatably disposed on the stand 40, one end of the screw rod is connected to a motor 704 for driving the screw rod to rotate and is fixed on the stand 40, the transition block 702 is slidably disposed on the stand 702, a sliding block 705 is further connected to the transition block 702, the sliding block 705 is slidably disposed on a sliding rail 706 extending along the vertical direction Z, and the sliding rail 706 is disposed on the stand 40.

Of course, in other embodiments, the third driving mechanism 70 may be implemented by a rodless cylinder, a hydraulic cylinder, or an electric push rod.

In addition, after the reagent strips are transferred to the tray 200 by the multifunctional robot, the protective film on the reagent strips needs to be opened so that the notches of the grooves thereon can be exposed for the subsequent operation.

Therefore, as shown in fig. 21 and 22, the film opening device 400 is further included to puncture the protective film of the reagent strip on the tray, the film opening device 400 includes a row of film opening cones 410 arranged along the extending direction of the limiting groove 210, the film opening cones 410 are vertically arranged and are normally located above the tray 200, and the number of the film opening cones 410 is consistent with and corresponds to the number of the material grooves on the reagent strip, so that the film opening cones 410 can complete the film opening of all the material grooves on one reagent strip at a time, a row of film opening cones 410 is located below a vertical plate 440, and the vertical plate 440 is connected with a film opening driving device 420 for driving the film opening driving device 420 to move horizontally.

As shown in fig. 22, the film opening driving device 420 includes a cylinder 421, a cylinder shaft of the cylinder 421 is vertically disposed and fixed on a sliding table 422 located outside the tray fixing jig 200, a body of the cylinder 421 is slidably disposed on a first longitudinal guiding rail 424 extending along a vertical direction (a direction perpendicular to both the first horizontal direction Y and the second horizontal direction X) through a first sliding block 423, the first longitudinal guiding rail 424 is fixed on a side portion of the sliding table, a Z-shaped mounting rod 425 for mounting the film opening cone 410 is fixed on the first sliding block 423, and the mounting rod 425 extends out of a side of the sliding table close to the tray fixing jig 200.

As shown in fig. 22, the horizontal driving device 430 includes a motor 431, the motor 431 is connected to a horizontal screw 432 perpendicular to the limit groove and drives the screw of the horizontal screw 432 to rotate, an interaction nut of the horizontal screw 432 is connected to the sliding table 422, and the sliding table 422 is slidably disposed on two horizontal rails 423 parallel to the horizontal screw 432.

Further, in order to avoid that the reagent strip is shifted under the action of lifting force or is removed from the limit groove of the tray during the process of opening the cover, therefore, when the cover is opened, a pressing force needs to be applied to the reagent strip on the tray to avoid that the reagent strip is pulled up, as shown in fig. 22, a pressing rod 500 is further provided on the sliding table 422, the extending direction of the pressing rod 500 is perpendicular to the extending direction of the limit groove, the length of the pressing rod 500 is not less than the sum of the widths of all the limit grooves 210, the pressing rod 500 is connected with a pressing driving mechanism 600 for driving the pressing rod 500 to move vertically, the pressing driving mechanism 600 has the same structure as the above-mentioned film opening driving device 420, and comprises a lifting cylinder 610, the cylinder shaft of the lifting cylinder 610 is fixed on the sliding table 422, the cylinder body of the lifting cylinder 610 is slidably provided on a second longitudinal guide rail 630 extending along the vertical direction, the second longitudinal guide rail 630 is fixed on the side of the sliding table 422, a pressing rod 640 is fixed on the second sliding block 620, and a pressing rod 640 is used for installing the pressing rod 500 is installed on the side of the sliding table, and thus, the pressing rods 500 can be independently translated, and the pressing rods 500 can be independently translated.

After the protection film on the reagent strip is opened, the protection cover is opened, and the probe is transferred, the test solution is required to be added into the corresponding groove on the reagent strip to realize the corresponding reaction, therefore, as shown in fig. 3, the pretreatment device further comprises a test solution storage mechanism 2000, which is positioned at the side of the material storage device 100 and is provided with a group of containers, the containers can be selected according to the need, for example, test tubes, liquid storage bottles and the like, and are arranged on a container frame, and meanwhile, the container frame can reciprocate along the second horizontal direction X, and the container frame is connected with a cylinder for driving the container frame to move.

As shown in fig. 3, the pretreatment device further includes an injection mechanism 3000 configured to extend into a slot in any of the containers for aspirating and injecting material onto the tray.

Specifically, as shown in fig. 23, the injection mechanism 3000 includes at least a vertical suction nozzle connection pipe 02, and a suction injection mechanism connected to the upper end of the suction nozzle connection pipe 02, wherein the suction nozzle connection pipe is connected to a mechanism for driving the suction nozzle connection pipe to move horizontally in the first horizontal direction Y and/or the second horizontal direction X and to move horizontally in the vertical direction Z, and the suction injection mechanism moves horizontally in synchronization with the suction nozzle connection pipe.

As shown in fig. 24, the nozzle connecting tube 02 is configured to be connected to a nozzle in use, and has a cylindrical tubular shape, so as to be connected to the nozzle conveniently, and the lower portion of the nozzle connecting tube 02 includes a spherical head 021, a thin straight tube section 022, a conical tube section 023 and a thick straight tube section 024 sequentially arranged from bottom to top.

As shown in fig. 23, the nozzle connection pipe 02 is connected to a moving mechanism 04 for driving the nozzle connection pipe to move in the vertical direction Z and at least one of the first horizontal direction Y and the second horizontal direction X perpendicular to the first horizontal direction, and the moving mechanism 04 may be a device such as a six-axis robot or a four-axis robot.

In a more preferred embodiment, as shown in fig. 24, the moving mechanism 04 includes a mounting block 041, the nozzle connecting tube 02 is disposed on the mounting block 041, the mounting block 041 is slidably disposed on a guide rail 043 extending along a vertical direction Z through a sliding block 042, the guide rail is fixed on a mounting stand 044, the mounting block 041 is connected to a belt 045, the belt 045 is sleeved on two synchronizing wheels 046, the mounting heights of the two synchronizing wheels are designed according to the required lifting height of the nozzle connecting tube 02, the synchronizing wheel located at the lower position is fixed at the lower end of the mounting stand 044, the synchronizing wheel 045 located at the upper position is coaxially connected with a motor shaft of a lifting motor 047, and the lifting motor 047 is fixed, so that the moving mechanism drives the nozzle connecting tube to be infinitely lifted along the vertical direction.

As shown in fig. 23 and 24, the mounting stand 044 is directly or through other supporting members connected with two sliding members 048 on two opposite sides thereof, the two sliding members 048 are slidably erected on two guide strips 049 extending along the first horizontal direction Y, one sliding member 048 is connected with a driving belt 0410 through a connecting member, the driving belt 0410 is sleeved on two driving rollers 0420, one driving roller is rotatably arranged on the translation frame 0430, and the other driving roller is coaxially connected with a first translation motor 0440 fixed on the translation frame 0430.

As shown in fig. 23, the translational frame 0430 is slidably disposed on the lifting frame 0450, and a driving mechanism for driving the translational frame 0430 to reciprocate along the second horizontal direction X is disposed on the lifting frame 0450, and the driving mechanism also adopts a structure composed of a motor 0460, a synchronizing wheel 0470 and a synchronizing belt 0480, which will not be described herein. Of course, the driving mechanism may also adopt a rodless cylinder, a linear motor and other devices.

Further, in order to avoid damage to the suction nozzle caused by excessive downward movement of the suction nozzle connecting pipe 02 when the suction nozzle connecting pipe 02 is inserted into the suction nozzle, in a more preferred embodiment, as shown in fig. 24, the suction nozzle connecting pipe 02 is inserted into the mounting block 041 in a manner of being movable along the vertical direction Z, and a limiting block 025 positioned on the mounting block 041 is arranged on the suction nozzle connecting pipe 02, so that the suction nozzle connecting pipe cannot fall from the mounting block 041, and further, a boss 026 positioned below the mounting block 041 is formed on the outer wall of the suction nozzle connecting pipe 02, and a spring 08 sleeved on the periphery of the suction nozzle connecting pipe is arranged between the boss 026 and the mounting block 041.

After the suction nozzle connection pipe 02 is connected to the suction nozzle, a sucking operation and an injecting operation are required, and therefore, as shown in fig. 23 and 24, the suction injection mechanism 07 is connected to the upper end of the suction nozzle connection pipe 02, and the suction injection mechanism 07 moves in a translational motion along with the suction nozzle connection pipe 02. As shown in fig. 24, the suction injection mechanism 07 includes a transfer tube (not shown) having one end connected to the upper end of the suction nozzle connection tube, the transfer tube may be a hose or a telescopic tube, the other end of the hose is connected to an inlet and outlet of a syringe 071, the syringe 071 is horizontal, the axis of the syringe 071 is perpendicular to the axis of the suction nozzle connection tube 02, the piston rod 072 of the syringe 071 is connected to a push-pull mechanism 073 driving the syringe to reciprocate along the axis of the syringe, and the push-pull mechanism 073 may be various known possible structures, for example, a hydraulic cylinder or an electric push rod, etc. which can drive the stepless movement of the piston rod 072 to flexibly control the amount of each injection. Preferably, the push-pull mechanism 073 includes a push-pull driving motor 0731, a motor shaft 0732 of the push-pull driving motor 0731 extends to a length outside of a housing thereof not smaller than a movement stroke of the piston rod 072, a movable nut 0733 is disposed on the motor shaft 0732, the movable nut 0733 switches rotation movement of the motor shaft into self linear movement, specifically, the movable nut 0733 and the motor shaft 0732 form a screw structure, and the movable nut 0733 is connected with the piston rod 072. Further, the movable nut 0733 is movably disposed on a guide rail 0735 parallel to the motor shaft by a slide mount 0734.

More preferably, in order to effectively control the accuracy of suction and injection, as shown in fig. 24, a valve body 074 is connected between the hose and the syringe, the valve body 074 is an adjustable electromagnetic valve, the valve body is fixed on a valve seat 075, the valve seat 075 is fixed on the mounting stand 044, and the valve seat 075 is provided with a channel connected with an inlet and an outlet of the syringe and the valve body, so that the injection amount can be adjusted by controlling the flow of the valve body 074.

As shown in fig. 23 and 24, the two suction nozzle connection pipes 02 are preferably two and can be respectively lifted and connected with one suction injection mechanism 07, and the structure for driving the two suction nozzle connection pipes 02 to lift and the two suction injection mechanisms 07 are symmetrically arranged on the mounting stand.

In the test, if only one or two kinds of test liquids are required to be sucked, the suction nozzle can be manually inserted into the suction nozzle connecting pipe without replacement, but in actual operation, a plurality of different test liquids are often sucked, the test liquids can be body fluid of a human body or liquid medicine required by other tests, and the like according to different test requirements, the suction nozzle sucked with one test liquid can obviously not be used for injecting the other test liquid, therefore, the suction nozzle on the suction nozzle connecting pipe is required to be replaced, as shown in fig. 25-28, the automatic injection device further comprises a blanking device 06 which comprises a limiting plate 061 which is positioned in the moving range of the suction nozzle connecting pipe 02 and is perpendicular to the suction nozzle connecting pipe, the limiting plate 061 is fixed on the blanking groove 062, at least one perforation 063 and blanking holes 064 communicated with the perforation 063 are formed on the limiting plate 061, preferably, a blanking hole 063 is communicated with each perforation 063 by side, and the perforation 063 is communicated with the four holes, and the distance between the perforation 063 and the two ends 064 of the perforation are kept to be smaller than the coaxial between the two perforation walls 066 and the two perforation walls 066. The limiting plate 061 is fixed on the blanking groove 062, and a bottom blanking opening of the blanking groove 062 is communicated with a notch at the top of a waste collecting groove 09.

As shown in fig. 27, when the through hole 063 is a circular hole through which the suction nozzle passes, the discharging hole 064 is a rectangular hole, the space between the two ends 065, 066 is the width of the rectangular hole and is smaller than the diameter of the through hole 063, or the discharging hole 064 may be a triangular hole or a trapezoid hole, etc., so that when the suction nozzle connecting pipe 02 moves to the position of the discharging hole 064, the top of the suction nozzle is located outside the two sides of the discharging hole 064, and when the suction nozzle connecting pipe 02 moves upwards, the suction nozzle is blocked by the limiting plate 061 to be separated from the suction nozzle connecting pipe 02.

After unloading the suction nozzle on the suction nozzle connecting pipe, a new suction nozzle needs to be replaced, therefore, an automatic suction nozzle supply mechanism is arranged beside (left side of) the material storage device,

As shown in FIGS. 28-32, the automatic nozzle supply mechanism includes

The storage bin 01 is provided with a storage space 011 for storing the multi-layer stacked cartridges 001, the bottom of the storage bin is provided with a feed opening 012, and the cartridges can be moved out of the storage bin 01 from the feed opening 012 under the action of gravity.

The material box 001, when the material box is in the storage space 011, the side wall of the material box is close to the inner wall of the storage bin 01, and the side wall of the material box 001 comprises a first side wall 0011 positioned above and a second side wall 0012 positioned below the first side wall and having a height smaller than that of the first side wall 0011, the distance between the first side wall 0011 and the inner side surface of the storage bin 01 is greater than that between the second side wall 0012 and the inner side surface of the storage bin, and the second side wall 0012 is close to or attached to the inner side surface of the storage bin 01, and the height is about half of that of the first side wall 0011. When stacking, the second side wall area of the last material box is sleeved on the first side wall area of the next material box.

The conveying jig 03 can move between a first horizontal position and a second horizontal position, the conveying jig 03 is positioned below the storage bin 01 for a certain distance and corresponds to a feed opening of the storage bin, and the material box 001 separated from the conveying jig can directly fall into the waste collection tank 09 at the second horizontal position, the material box is positioned outside the storage bin and is a notch of the waste collection tank 09 right below the storage bin.

The automatic discharging mechanism 05 can move the stacked material boxes 001 to the conveying jig at the first horizontal position one by one. The clamping arms are symmetrically arranged and can be lifted between a discharging opening of the storage bin and the conveying jig, in a first state, as shown in fig. 31 and fig. 33, opposite surfaces 0511 and 0512 of the two clamping arms 051 are positioned on the outer sides of opposite side edges 0121 and 0122 of the discharging opening 012, at the moment, the clamping arms do not provide support for a material box 001 positioned in the storage bin, and in a second state, opposite surfaces 0511 and 0512 of the two clamping arms are positioned on the inner sides of opposite side edges 0121 and 0122 of the discharging opening, and at the moment, the clamping arms provide support for the material box 001 positioned in the storage bin.

In a preferred embodiment, as shown in fig. 31, the storage bin 01 is a cuboid with an open bottom and an open side assembled by three side plates 013 and a top plate 014, the enclosed area is the storage space 011, and the open side of the storage bin 01 is arranged outwards, so that the additive box 001 is added into the storage space 011.

As shown in fig. 32, a door 015 capable of covering at least part of the side opening is arranged on the storage bin 01, and the specific structure of the door 015 can be designed according to the requirement. The storage bin 01 is provided with a locking device for keeping the door in a closed state, a connecting plate 016 is vertically arranged at the side edge of a main baffle plate of the door 015, a lock hole 017 is formed at the connecting plate 016, the locking device comprises a locking pin (not shown in the figure) which vertically penetrates through a side plate 0131 and corresponds to the lock hole 017 on the door in the closed state, one end of the locking pin facing the connecting plate 016 is pointed, the locking pin is connected with a driving cylinder 018 for driving the locking pin to reciprocate along the axial direction of the locking pin, the driving cylinder 018 is fixed on the side plate 0131 and drives the locking pin to be inserted into the lock hole 017, and when the driving cylinder 018 drives the locking pin to withdraw from the lock hole 017, the door 015 can be opened.

In a preferred embodiment, the door 015 is connected to an elastic device that drives the door to be automatically opened by a closed state, and the elastic device may be a torsion spring (not shown in the drawings), and the specific installation manner is a known technology and will not be described herein. The torsion spring deforms and stores force when the door 015 is closed, and releases stored energy to reset when the locking pin releases the locking of the door 015, so that the door 015 is automatically opened.

The conveying jig 03 is used for conveying the cartridges 001 falling onto the cartridges 01 from the storage bins 01 to the outer side of the storage bins 01 for use. As shown in fig. 30, the apparatus specifically includes a base plate 031, where a limiting structure for limiting the cartridge 001, such as a plurality of limiting blocks, a plate, a limiting pin, etc., is disposed on the base plate 031, and specifically, the apparatus is not limited herein, and is designed according to the structure of the cartridge 001 to be conveyed. The distance from the bottom plate 031 to the bottom of the side plate of the storage compartment 01 is designed according to the height of the cartridge 001 so that the cartridge 001 can be removed from the bottom of the storage compartment 01 when it falls onto the bottom plate 031.

As shown in fig. 30, the bottom plate 031 is slidably disposed in guide grooves 033 formed on two parallel vertical plates 032 and is connected to a translational driving mechanism 034 for driving the bottom plate to translate along the guide grooves 033, and each vertical plate 032 and one side plate 013 of the storage compartment 01 are integrally formed, and of course, they may be engaged by a joint plate, or they may not be connected.

As shown in fig. 30, one of the two guide grooves 033 is a through groove, the bottom plate 031 has a connection portion 035 passing through the through groove, a portion of the connection portion 035 extending to the outside of the vertical plate is connected to a movable nut of a screw 036, the movable nut is further slidably connected to a slide rail 038 located on the outer side of the vertical plate through a guide block 037, a screw rod of the screw 036 is connected to a motor 039 driving the screw rod to rotate, and the motor 039 is fixed on the outer side of the vertical plate.

The motor, the screw rod, the guide block 037 and the sliding rail 038 form the translation driving mechanism 034, and when in operation, the motor 039 drives the movable nut of the screw rod 036 to translate, thereby driving the bottom plate 031 to move and further realizing the integral translation of the conveying jig. Of course, in other embodiments, the translational driving mechanism 034 may also use a device capable of generating linear movement, such as a rodless cylinder or a hydraulic cylinder, instead of the motor and the screw rod.

And when the conveying jig 03 moves to the second horizontal position, two vertical plates are provided with limiting surfaces extending to the space between the two vertical plates, the limiting surfaces are slightly higher than the top surface of the side wall of the material box 001 on the conveying jig 03, and the limiting surfaces are the bottom surfaces of two height limiting blocks 0310.

The automatic discharging mechanism 05 is used for transferring the material boxes 001 in the storage bin 01 onto the conveying jig 03, and providing support for other material boxes 001 so as not to fall off when the conveying jig 03 moves to the outer side of the storage bin 01.

Specifically, as shown in fig. 34, two clamping arms 051 of the automatic blanking mechanism 05 are horizontal, and avoidance notches for moving the clamping arms 051 are formed in the side plates and the vertical plates, each clamping arm 051 is connected with a vertical rod 052 which is L-shaped, the vertical rods 052 are located on the outer sides of side plates 0133 with opposite side portions open to the storage bin 01, an installation block 053 is connected to the upper ends of the vertical rods 052, the installation block 053 is slidably arranged on a guide rail 055 extending along the direction perpendicular to the moving direction of the conveying jig 03 through a sliding block 054, the guide rail 055 is fixed on the side plates 0133, a spring 056 is arranged between the two installation blocks 053, and two ends of the spring 056 are respectively fixed on the two springs 056, and the two clamping arms are kept in a second state under the normal state of the spring 056.

Of course, in other embodiments, two clamping arms 051 may be connected to two sliding blocks of one clamping jaw cylinder by a bracket.

In a preferred embodiment, as shown in fig. 34, the guide rail 055 is fixed on a transfer block 057, the transfer block 057 is connected with a lifting driving device 058 for driving the transfer block to lift, and the lifting driving device 058 can be a cylinder or other devices capable of generating linear movement, such as a hydraulic cylinder, and the transfer block 057 is guided by a guide shaft and a shaft sleeve.

In a preferred embodiment, in order to realize automatic opening and closing of the two clamping arms 051, as shown in fig. 34 and fig. 35, each mounting block 053 is rotatably provided with a roller 059 towards the side of the storage bin 01, the axis of each roller 059 extends along the moving direction of the conveying jig, two rollers 059 are respectively embedded in a groove 0510, the groove 0510 comprises a vertical section 0520 and an inclined section 0530, the rollers 059 are in the vertical section 0520, the two clamping arms keep a first state, namely the two clamping arms keep a closed state, so that the support can be provided for a material box 001 on the two clamping arms, the two clamping arms keep a second state, namely the two clamping arms are in an open state, the material box 001 on the two clamping arms are not supported, at the moment, the clamping arms keep a certain distance from the top of the conveying jig 03 so that the material box falls onto the conveying jig 03, and then the two clamping arms can clamp other material boxes when the clamping arms are in a closed state.

Meanwhile, when the roller moves to the tail end of the inclined section 0530, the top surfaces of the clamping arms 051 and the conveying jig are as close as possible, so that the drop of the material box from the clamping arms to the conveying jig is reduced as much as possible.

As shown in fig. 35, the side of the vertical section is formed with an arc-shaped notch 0540 at a high position, and the distance between two arc-shaped notches 0540 is smaller than the distance between two vertical sections 0520, so that two clamping arms can better support the cartridge 001 thereon.

Preferably, in order to reduce the translation stroke of the nozzle connection pipe of the injection mechanism, the tray is moved to a position adjacent to the nozzle connection pipe, so that the pretreatment device further comprises a device as shown in fig. 3,

The tray positioning jig h is provided with a limiting structure for positioning the tray;

the tray transfer mechanism has a structure for moving the tray between the tray fixing jig 300 and the tray positioning jig h.

Specifically, as shown in fig. 3, the tray positioning jig h is located at the inner side of the automatic suction nozzle supply mechanism and is adjacent thereto, and the tray positioning jig h is opposite to the tray fixing jig 300 in the second horizontal direction X, so that the structure of the moving part of the tray transfer mechanism can be simplified.

As shown in fig. 36, the tray transfer mechanism comprises

The tray clamping jaw c comprises two clamping rods c1 which are equal in height and horizontally extend and an opening and closing driving device for driving the clamping rods c1 to open and close, and the clamping rods c1 are perpendicular or parallel to the blanking plate b;

The clamping jaw overturning mechanism d is connected with the tray clamping jaw c and drives the tray clamping jaw c to rotate around an axis vertical to or parallel to the blanking plate;

and the moving mechanism e drives the clamping turnover mechanism to translate and lift in a preset range.

The tray clamping jaw c is used for clamping the tray 200 so as to facilitate the movement of the tray 200, as shown in fig. 36 and 37, the extending direction of two clamping rods c1 is preferably perpendicular to the blanking plate b, positioning pins c11 corresponding to notches on the tray are formed on the clamping rods c1, and the two clamping rods c1 are driven to be opened and closed by one double-headed motor c 2. The opening and closing driving device has the following specific structure:

As shown in fig. 37, a motor shaft extending to the outside of two ends of the double-headed motor c2 is respectively provided with a translation block c3, the translation block c3 can switch the rotation motion of the motor shaft into the self linear motion of the motor shaft, for example, the translation block c3 and the motor shaft form a screw rod structure, the translation block c3 is connected with the clamping rod c1 through a connection block c4, the clamping rod c1 is connected with the connection block c4 through a connection block with an L-shaped tail end, the connection block is fixed with a sliding block c5, and the sliding block c5 is slidably arranged on a horizontal guide rail c6 perpendicular to the clamping rod c 1.

Further, as shown in fig. 37, in order to effectively support the motor shaft, motor shafts extending to the outside of both ends of the double-headed motor c2 are rotatably provided on the support plates c71 on both sides of the motor housing c 7.

As shown in fig. 37, the jaw tilting mechanism d is a rotary cylinder connected to the motor base c7 or a turntable driven by a motor, and the axis of the rotary cylinder or the motor is parallel to the extending direction of the clamping rod c 1.

As shown in fig. 36, the moving mechanism e is configured to drive the tray jaw to move within a predetermined range, which can move the clamping lever of the tray jaw between the up and down positions of the blanking plate b and drive the clamping lever to move outside the blanking plate b to correspond to the position of the blanking plate in the vertical direction, that is, the clamping lever can extend from one side of the blanking plate to the other side.

As shown in fig. 36, the moving mechanism e includes a lifting driving mechanism for driving the jaw tilting mechanism to reciprocate in a vertical direction and a horizontal driving mechanism for driving the lifting driving mechanism to horizontally move in a direction parallel to the blanking plate, wherein the lifting driving mechanism and the horizontal driving mechanism respectively use a motor as a power source.

Specifically, as shown in fig. 36, the lifting driving mechanism includes a sliding seat e1, the sliding seat e1 is slidably disposed on a guide rail e2 extending along a vertical direction z, the sliding seat e1 is connected with a belt e3, the belt 13 is sleeved on two rollers (not shown in the drawing), the axes of the rollers are perpendicular to the blanking plate b, one roller is located above the tray positioning jig h and is fixed on a sliding frame e4, the other roller is located below the blanking plate and is coaxially connected with a lifting driving motor e5, and the lifting driving motor e5 is fixed on the sliding frame e 4.

The sliding frame e4 is connected with the horizontal driving mechanism, the structure of the horizontal driving mechanism is the same as that of the lifting driving mechanism, the sliding frame e4 is driven to move along a horizontal guide rail e6 parallel to the blanking plate by a translation motor, a belt and a belt wheel, the horizontal guide rail e6 extends along a first horizontal direction Y, two ends of the horizontal guide rail e6 extend to the outer sides of the tray positioning jig and the tray fixing jig, and the horizontal guide rail is fixed on a side plate (not shown in the figure). The moving mechanism e can drive the tray clamping jaw to place the tray on the tray positioning jig h.

Further, after the test is completed, the reagent strips on the tray 200 need to be unloaded from the tray 200 to facilitate reuse of the tray 200, so as shown in fig. 36, the pretreatment device further includes a blanking plate b, which is vertically disposed and is vertical or parallel to the limit groove of the tray on the tray fixing jig, and as shown in fig. 38, the lower end surface of the blanking plate b is a set of planes b1-b10 with height differences.

As shown in fig. 36, the blanking plate b is fixed at the bottom of a horizontal carrier plate f of a carrier plate, an automatic turntable g is arranged on the carrier plate f, a tray positioning jig h is arranged on the turntable g, and the automatic turntable g is used for driving the tray 200 to rotate 90 ° around the axis of the automatic turntable so as to quickly add the test solution into the reagent strips on the tray through the test solution adding mechanism.

As shown in fig. 39 and 40, the automatic turntable g includes a rotating base g1 rotatably disposed on the carrier plate, a rotating shaft g11 of the rotating base g1 is rotatably disposed on the carrier plate f through a bearing (not shown in the drawing), a seat plate g12 is disposed on top of the rotating shaft g11 and is sleeved with a driving wheel g2 disposed between the carrier plate f and the seat plate, the driving wheel g2 is connected with a driving wheel g4 through a driving belt g3, a diameter of the driving wheel g4 is not more than 1/4 of a diameter of the driving wheel g2, the driving wheel g4 is coaxially connected with a motor shaft of a motor g5, the motor g5 is fixed at bottom of the carrier plate f, and the motor shaft vertically passes through the carrier plate f.

In addition, as shown in fig. 40, an adjusting block g6 is further disposed on the top surface of the carrier plate f, the adjusting block g6 is disposed on the carrier plate f in a manner that a waist-shaped hole is formed in the adjusting block g6 in a position adjustable manner, a tensioning wheel g7 is disposed on the adjusting block g6 in a manner that the adjusting block g6 can rotate, an axis of the tensioning wheel g7 is parallel to an axis of the motor, a wheel surface of the tensioning wheel is in contact with the driving belt g3, and tensioning of the driving belt g3 can be achieved by adjusting the position of the tensioning wheel g 7.

In a more preferred embodiment, as shown in fig. 39, a gantry guiding frame g8 is further disposed on the carrier plate f, and the rotating shaft g11 is rotatably connected with the gantry guiding frame g8 through a bearing.

During operation, the tray clamping jaw c clamps the tray 200 from two sides of the tray 200 through two clamping rods c1, then, the clamping jaw overturning mechanism d drives the tray clamping jaw c to drive the tray 200 to overturn 180 degrees, so that the bottom of the tray 200 faces upwards, then, the moving mechanism e drives the tray clamping jaw c to drive the tray 200 to move to the lower side of the blanking plate b, the blanking plate b corresponds to one reagent strip limiting groove 210 of the tray 200, then, the tray 200 is continuously lifted, the lower end face of the blanking plate b is in contact with the reagent strips in the reagent strip limiting groove, and as the tray 200 continues to ascend, the reagent strips can be pressed out of the reagent strip limiting groove 210 where the reagent strips are located to finish blanking.

Or in another embodiment, the blanking plate b may be made to correspond to a gap 215 on the tray 200 perpendicular to the reagent strip limiting groove, and then the moving mechanism e drives the tray 200 to further ascend, so that the blanking plate b may apply a pushing force to one end of the plurality of reagent strips, and thus the plurality of reagent strips are extruded from the corresponding reagent strip limiting groove to complete blanking. In addition, as the lower end face of the blanking plate b is provided with a plurality of planes with height differences, different positions of the blanking plate b can be contacted with corresponding reagent strips according to a certain sequence, so that blanking can be performed at different times, and compared with a plane blanking mode, the structure is more labor-saving and is beneficial to ensuring the reliability of blanking.

In practical use of the apparatus, the number of trays 200 may be plural, so that the reagent strips may be transferred, opened and prepared for injection of the test solution on the tray positioning jig at the same time when the reagent strips enter the test load for testing.

In the automatic operation process of the whole equipment, the automatic operation of each mechanism can be controlled by combining various sensors through a control device such as a PLC (programmable logic controller), and the corresponding structure and control technology are known technologies and are not important points of the scheme, so that the description is omitted here.

The scheme also discloses medical equipment, which comprises the test pretreatment device of the embodiment.

The scheme further discloses a detection method, which at least comprises the following steps:

S1, fixing a tray on a tray fixing jig.

the S3 specifically comprises

S30, manually placing at least one tray carrying the reagent strips into the reagent strip tray limiting groove 21 of the drawer, wherein at the moment, the corresponding sensor of the reagent strip tray limiting groove 21 determines that the tray is arranged in the reagent strip tray limiting groove 21.

S31, the control device controls the horizontal moving mechanism 100 and the second driving mechanism 50 of the multifunctional manipulator to drive the electromagnetic adsorption device 9 to move to the drawer with the tray, the electromagnetic adsorption device generates magnetic force to adsorb the drawer when being electrified, then the horizontal moving mechanism 100 drives the electromagnetic adsorption device 9 to translate and open the drawer adsorbed by the electromagnetic adsorption device, and after the drawer is opened, the electromagnetic adsorption device 9 is powered off. The drawer is restricted from being closed by an open state by a first stop mechanism or a second stop mechanism on the reagent strip storage device.

S32, the control device controls the code reader on the multifunctional manipulator to start reading the bar codes on the reagent bars in the tray to determine the types, the numbers and the positions of the reagent bars.

And S33, controlling the horizontal moving mechanism and the second driving mechanism 50 to move the multifunctional manipulator according to the determined number and positions of the reagent strips, and clamping the reagent strips in the tray one by one and moving out of the drawer through the first clamping mechanism 20 and the second clamping mechanism 30 on the multifunctional manipulator, wherein at the moment, the first clamping mechanism 20 clamps the two sides of the reagent strips, and the second clamping mechanism 30 clamps the two ends of the protective cover at the end part of the reagent strips.

And S34, after the reagent strips are moved out of the drawer, the first limiting mechanism or the second limiting mechanism releases the limitation on the drawer, and the control device controls the horizontal moving mechanism 100 and the second driving mechanism 50 of the multifunctional manipulator to drive the electromagnetic adsorption device 9 to move and close the drawer for completing the transfer of the reagent strips.

If the material is not a reagent strip, the test solution can be directly added into the groove on the material when the protective film and the protective cover are not arranged on the material.

S5, at this time, the material on the tray can be sucked from the appointed container through the injection mechanism and injected into the groove of the material on the tray in a metering mode.

Further, when the reagent strip with the protective film is processed, S41 is further provided between S3 and S5, the protective film on the surface of the material on the tray is punctured by the film opening mechanism, specifically, the film opening cone 410 is driven by the horizontal driving device 430 to move onto one reagent strip, and then the film opening cone 410 is driven by the film opening driving device 420 to move down to complete film opening and then reset. When the film opening operation is performed, the film opening operation can be performed once after each reagent strip moves onto the tray, or the film opening operation can be performed in batches after all required reagent strips are transferred onto the tray.

Further, when the reagent strip with the protective cover is processed, S42 is arranged between the S3 and the S5, the protective cover on the material is opened through the cover opening mechanism, and the probe is taken out from the material and placed on the tray through the probe transfer mechanism. Specifically, the horizontal driving device 430 drives the pressing rod 500 to move above all the reagent strips, the pressing driving mechanism 600 drives the pressing rod 500 to move downwards to press all the reagent strips on the tray 200, then the horizontal moving mechanism 100 drives the first cover plate 801 and the second cover plate 803 to move to the end parts of the protective covers of all the reagent strips on the tray, then the fourth driving mechanism 90 drives the first cover plate 801 and the second cover plate 803 to move downwards to abut against the end parts of the protective covers, and then the fourth driving mechanism 90 and the horizontal moving mechanism 100 drive the first cover plate 801 and the second cover plate 803 to move upwards and translate to the outer sides of the tray.

Then, the horizontal driving device 430 drives the probe clamping jaw 60 to move above the probe above the reagent strip, then the third driving mechanism 70 drives the probe clamping jaw 60 to move downwards so that the first clamping block 604 and the second clamping block 607 are positioned at two sides of the probe, then the second motor 601 drives the first clamping block 604 and the second clamping block 607 to be closed so as to clamp the probe, the third driving mechanism 70 drives the probe clamping jaw 60 to ascend, and then the horizontal driving device 430 drives the probe clamping jaw 60 to move so as to move the probe thereon to the probe containing hole on the tray.

After the film opening and uncovering actions are completed, an S43 is further arranged between the S3 and the S5, and the tray 200 is moved onto the tray positioning jig h from the tray fixing jig 300 through the tray transferring mechanism. Specifically, the tray fixing jig releases the fixing of the tray, the moving mechanism e drives the two clamping rods c1 of the tray clamping jaw c to move to two sides of the tray, then the tray clamping jaw c clamps the tray, then the moving mechanism e drives the tray clamping jaw c to move to the tray positioning jig, and then the clamping rods c1 of the tray clamping jaw c release the tray.

The automatic turntable g drives the tray fixing jig 300 to rotate 90 degrees, so that reagent strips on the tray on the automatic turntable g are switched from extending along the second horizontal direction X to extending along the first horizontal direction Y, and at the moment, test liquid is conveniently and synchronously added into the reagent strips through two suction nozzle connecting pipes to improve the efficiency.

The step S3 includes, before the test solution is sucked, stacking and placing a plurality of cartridges with suction nozzles in the storage bin 01 manually, closing the door 015, at this time, the conveying jig 03 is located at a first horizontal position, two clamping arms 051 of the automatic discharging mechanism 05 are opened to enable a lowermost one of the cartridges to fall onto the conveying jig 03, then the lifting driving device 058 drives the clamping arms to move upwards and close simultaneously, at this time, two clamping arms 051 clamp one of the cartridges above the cartridge located on the conveying jig 03 and separate all of the cartridges thereon from the cartridge on the conveying jig 03, at this time, the translational driving mechanism 034 drives the conveying jig 03 to be conveyed from the first horizontal position to the second horizontal position.

At this time, the moving mechanism 04 drives the nozzle connecting pipe 02 to the nozzle inserted on the cartridge on the conveying jig 03 at the second horizontal position as required, and moves the nozzle to the outside of the cartridge for sucking and injecting.

Before different test liquids are sucked, the suction nozzle on the suction pipe connecting nozzle is unloaded through the blanking device, and the suction nozzle connecting pipe is moved to the conveying jig at the second horizontal position to replace the suction nozzle. Specifically, the moving mechanism 04 drives the suction nozzle connecting pipe 02 to insert the suction nozzle 002 thereon into the through hole 063 on the limit plate 061 and make the top of the suction nozzle 002 below the through hole, and then translates the suction nozzle connecting pipe to the pipe wall of the suction nozzle thereon to be located outside the through hole, preferably to move into the discharging hole 064. Subsequently, the moving mechanism 04 drives the suction nozzle connecting pipe 02 to rise until the lower end of the suction nozzle connecting pipe 02 moves above the limit plate 061, and separation of the suction nozzle and the suction nozzle connecting pipe is completed. At this time, the moving mechanism 04 drives the suction nozzle connecting pipe 02 to be inserted with the suction nozzle on the material box and taken out to the outside for sucking and injecting.

When no more than 3 suction nozzles remain in the material box 001 positioned on the conveying jig 03 at the second horizontal position, the moving mechanism 04 drives the suction nozzle connecting pipe to be inserted into the suction nozzle or into a jack for inserting the suction nozzle, the translation driving mechanism drives the conveying jig to move from the second horizontal position to the first horizontal position, and the material box falls below the conveying jig under the action of gravity after the conveying jig moves to the outer side of the material box. When the conveying jig returns to the first horizontal position, the automatic discharging mechanism automatically drops a material box onto the conveying jig. And then the translation driving mechanism drives the conveying jig 03 to move from the first horizontal position to the second horizontal position, and the suction nozzle is supplied again. After the suction nozzle is installed, the moving mechanism 04 drives the suction nozzle on the suction nozzle connecting pipe 02 to move into a container containing the corresponding test liquid, then the sucking injection mechanism 07 drives the syringe to suck liquid, the amount of the sucked liquid does not enter the suction nozzle connecting pipe 02, and then the moving mechanism 04 drives the suction nozzle connecting pipe to move to the tail end of the suction nozzle connecting pipe to extend into the corresponding groove on the reagent strip and inject a certain amount of test liquid into the groove.

Further, after the addition of the test solution is completed on the tray positioning jig h, the automatic turntable g drives the tray fixing jig 300 to reversely rotate by 90 °, so that the reagent strips on the tray on the automatic turntable g are switched from extending along the first horizontal direction Y to extending along the second horizontal direction X, and then the moving mechanism e drives the tray clamping jaw c to clamp and move the tray into the testing device for testing, and the specific structure of the testing and testing device is not limited herein.

The method further comprises S07, after the test is completed, the moving mechanism e drives the tray clamping jaw c to move to the position of the tested tray for clamping and moving, the tray is turned 180 degrees through the clamping jaw turning mechanism d, the moving mechanism e drives the tray to move to the lower part of the blanking plate b, the blanking plate b applies a downward pressure to the top surface of the reagent strip in the tray 200 by lifting the tray 200 until the reagent strip falls from the limiting groove, and after the blanking is completed, the tray transferring mechanism turns the tray 180 degrees again and places the tray on the tray fixing jig 200. The above process is repeated.

The invention has various embodiments, and all technical schemes formed by equivalent transformation or equivalent transformation fall within the protection scope of the invention.

Claims

1. A pre-test processing device, characterized in that:

The tray has at least one limiting groove;

A pallet fixing jig has a structure for installing and fixing the pallet;

A material supply mechanism, which has a structure for storing materials in batches and transferring the materials one by one onto a pallet;

a test fluid storage mechanism having a set of containers;

The injection mechanism has a structure that can extend into any of the containers to suck liquid and inject it into the groove of the material on the tray; the injection mechanism at least includes a vertical nozzle connecting tube, a suction injection mechanism connected to the upper end of the nozzle connecting tube, the nozzle connecting tube is connected to a mechanism that drives it to move horizontally along the first horizontal direction Y and/or the second horizontal direction X and along the vertical direction Z, and the suction injection mechanism moves horizontally synchronously with the nozzle connecting tube;

The material supply mechanism includes

Material storage device with multiple layers of openable and closable drawers;

A multifunctional manipulator having an adsorption device for adsorbing the drawer and a first clamping mechanism for clamping materials in the drawer;

A moving mechanism, driving the multifunctional manipulator to move;

The multifunctional manipulator further comprises a code reader, which is tilted and has a lens facing downward and toward the material storage device;

The pre-test processing device also includes

The film opening mechanism comprises a row of film opening cones arranged along the extension direction of the limiting groove, the film opening cones are arranged vertically, and the row of film opening cones are connected to a mechanism for driving them to move vertically and horizontally synchronously;

The cover opening mechanism at least comprises a first cover opening plate, the first cover opening plate is vertical and perpendicular to the limit groove, and the first cover opening plate is connected to a mechanism for driving the lifting and translation of the first cover opening plate;

The probe transfer mechanism comprises a probe clamp and a mechanism for driving the probe clamp to rise, fall and translate. The probe transfer mechanism translates synchronously with the cover opening mechanism.

A pallet positioning fixture having a limiting structure for positioning the pallet;

The pallet transfer mechanism has a structure for moving the pallet between the pallet fixing jig and the pallet positioning jig;

A blanking plate, which is vertically arranged and perpendicular or parallel to the limiting groove of the pallet on the pallet fixing jig;

The tray transfer mechanism comprises

The pallet clamp includes two clamping rods of equal height and extending horizontally and an opening and closing driving device for driving them to open and close, wherein the clamping rods are perpendicular or parallel to the blanking plate;

A clamping jaw flipping mechanism, connected to the pallet clamping jaw and driving it to rotate around an axis parallel to the clamping rod;

The moving mechanism drives the clamping jaw flipping mechanism to move in translation and lifting, and the clamping rod moves between the upper and lower positions of the blanking plate and moves from the outer side of the blanking plate to a position corresponding to the blanking plate in the vertical direction.

2 . The pre-test processing device according to claim 1 , wherein the tray has at least 5 side-by-side limiting grooves. 3 .

3. The pre-test processing device according to claim 1 is characterized in that: the suction injection mechanism includes a syringe connected to the suction nozzle connecting tube and a mechanism for driving the piston rod of the syringe, and the suction nozzle is perpendicular to the syringe.

4. The pre-test processing device according to claim 1 is characterized in that: the injection mechanism also includes a feeder and an automatic nozzle supply mechanism located next to it, the feeder includes a limit plate located within the moving range of the nozzle connecting tube and perpendicular to the nozzle connecting tube, at least one through hole is formed on the limit plate, and when the nozzle connecting tube is coaxial with the through hole, its outer wall maintains a distance from the hole wall of the through hole.

5. The pre-test processing device according to claim 4, characterized in that: the automatic nozzle supply mechanism includes

The storage bin has a storage space for storing multiple layers of stacked objects, and its bottom is a discharge port;

A conveying jig, which is located a certain distance below the storage bin and can move between a first horizontal position and a second horizontal position. At the first horizontal position, it corresponds to the unloading port of the storage bin; at the second horizontal position, it is located outside the storage bin;

The automatic unloading mechanism can move the multi-layer stacked objects one by one to the conveying fixture at the first horizontal position.

6. The pre-test processing device according to claim 1 is characterized in that it includes a horizontal pressure rod, the extension direction of which is perpendicular to the limiting groove and is connected to a mechanism that drives its translation and lifting, and the pressure rod can be translated to just above the limiting groove.

7. The pre-test processing device according to claim 1 is characterized in that the lower end surface of the blanking plate is a set of planes with height differences.

8. Medical equipment, characterized in that it comprises the pre-test processing device according to any one of claims 1 to 7.

9. The detection method of the pre-test processing device according to any one of claims 1 to 7, characterized in that it comprises at least the following steps:

S1, the pallet is fixed on the pallet fixing fixture;

S3, the material supply mechanism moves at least one material to a limiting groove of the tray for limiting;

The S3 includes

S31, the suction device on the multifunctional manipulator suctions the drawer and opens the drawer;

S32, a barcode reader on the multifunctional robot reads the barcode on the material in the drawer to determine the type, quantity and location of the material;

S33, the first clamping mechanism on the multifunctional manipulator clamps at least one material in the drawer and moves it out of the drawer and places it in the limiting groove of the tray;

S5, the injection mechanism sucks liquid from the designated container and injects it into the groove of the material on the tray according to the metered amount;

It also includes S41 located between S3 and S5, which punctures the protective film on the surface of the material on the pallet through a film opening mechanism;

and/or

The protective cover on the material is opened by the cover opening mechanism, and the probe is taken out from the material and placed on the tray by the probe transfer mechanism;

and/or

The pallet is moved from the pallet fixing fixture to the pallet positioning fixture through the pallet transfer mechanism.

10. The detection method according to claim 9 is characterized in that: S3 includes, before sucking different test liquids, unloading the suction nozzle on the suction tube connecting nozzle through a feeder and moving the suction nozzle connecting tube to a conveying fixture at a second horizontal position to replace the suction nozzle.

11. The detection method according to claim 9 is characterized in that: it includes S07, after the test is completed, the pallet is flipped 180 degrees by the pallet transfer mechanism and moved to the bottom of the unloading plate, and the unloading plate applies downward pressure to the material in the pallet by lifting the pallet until the material falls from the limiting groove. After the unloading is completed, the pallet transfer mechanism flips the pallet 180 degrees again and places it on the pallet fixing fixture.