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CN112704477B - Core temperature measuring probe and method of sandwich type structure - Google Patents

Core temperature measuring probe and method of sandwich type structure Download PDF

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CN112704477B
CN112704477B CN202011530923.XA CN202011530923A CN112704477B CN 112704477 B CN112704477 B CN 112704477B CN 202011530923 A CN202011530923 A CN 202011530923A CN 112704477 B CN112704477 B CN 112704477B
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core temperature
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heat flow
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CN112704477A (en
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叶学松
周聪聪
任相林
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Zhejiang University ZJU
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/01Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01KMEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K11/00Measuring temperature based upon physical or chemical changes not covered by groups G01K3/00, G01K5/00, G01K7/00 or G01K9/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01KMEASURING TEMPERATURE; MEASURING QUANTITY OF HEAT; THERMALLY-SENSITIVE ELEMENTS NOT OTHERWISE PROVIDED FOR
    • G01K13/00Thermometers specially adapted for specific purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0271Thermal or temperature sensors

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Abstract

The invention relates to a core temperature measuring probe with a sandwich structure and a method thereof, relating to the technical field of human body parameter monitoring, wherein the probe comprises an outer layer heat insulation structure and an inner layer sandwich structure which is wrapped by the outer layer heat insulation structure in a ring manner; the inner-layer sandwich type structure sequentially comprises a measuring module, a heat-conducting filling material, a radiation isolation layer, air and a good heat-conducting layer from bottom to top; the measuring module comprises a circuit structure, and a temperature sensor and a heat flow sensor which are arranged on the circuit structure, wherein the temperature sensor and the heat flow sensor are both in contact with the heat-conducting pouring material. The invention can solve the problem that the heat flow is slowly established and is easily interfered in the single-channel heat flow technology.

Description

Core temperature measuring probe and method of sandwich type structure
Technical Field
The invention relates to the technical field of human body parameter monitoring, in particular to a core temperature measuring probe with a sandwich structure and a method.
Background
The core body temperature refers to the temperature of internal organs of a human body, is generally stabilized within the range of 36.5-37.5 ℃, and is generally regarded as the temperature of cranial cavity, abdominal cavity and thoracic cavity of the human body. Compared with the body surface temperature, the core body temperature is not easily influenced by external environment temperature fluctuation, sweat evaporation and personal clothing, so that the health condition of the body can be more accurately reflected. The core body temperature is maintained within a relatively narrow temperature range compared to the temperature of the superficial tissue, and a fluctuation of 4 ℃ up and down risks hyperthermia or hypothermia. The core body temperature can represent various individual states which cause the change of the core body temperature, including the metabolic rate, the female menstrual condition, the medicine intake and the like, and especially has more significance for severe patients, children and patients with anesthesia in operation who cannot accurately evaluate the body condition of the patients, and the accurate value of the core body temperature can be obtained in real time. Under the scenes of auxiliary diagnosis of sleep disorder patients, female physiological cycle management, biological thermal strain monitoring and the like, the continuous monitoring of the core body temperature can obtain more accurate biological rhythm prediction and physiological condition assessment. In the field of health management, it is more interesting to know the fluctuation of the core body temperature than to obtain the value of the temperature at a certain moment. In addition, there is a great deal of literature showing that fluctuations in human psychological and physiological activities are consistent with changes in core body temperature.
The core body temperature which is common in clinic is applied to screening fever, acquiring virus infection information and the like. In hospitals, nurses need to manually measure the body temperature of each patient every 4 hours by using a digital thermometer or an infrared thermometer, and the body temperature of a patient with fever is measured more frequently. This not only causes heavy workload for nurses, but also affects the rest of the patient, which is disadvantageous to the recovery thereof, and it is more difficult to measure the body temperature of the patient in a non-waking state.
The core body temperature monitoring equipment must meet the characteristics of long-term, real-time, noninvasive and accurate monitoring. Currently, core temperature monitoring techniques are mainly classified into invasive and non-invasive techniques. The thermal inertia of the rectal region causes the region to perfuse and lose relatively low heat, and the rectal temperature is therefore relatively high and is considered the gold standard for core body temperature. The heat of the blood vessels of the superior rectum and the hemorrhoidal artery is not easy to dissipate, and a thermometer can be directly inserted into the anus for measurement, but the peripheral skin can be rubbed and damaged if the operation method is not proper, and even the rectum is in danger of perforation. In addition, the direct insertion of thermometers into closed cavities such as pulmonary artery and bladder can also obtain accurate core body temperature. However, the above-mentioned cavities or organs are not suitable for continuous thermometer insertion and real-time core temperature acquisition, especially for awake subjects, and such invasive measurement method would impose a heavy psychological burden on the patient and require a professional physician to operate. The infrared temperature measurement technology is characterized in that the core body temperature is obtained by inserting a probe into an ear canal to measure the tympanic membrane temperature, the mode is simple and easy to use, the relative error between the core body temperature and the core body temperature measurement result reflected by the middle-lower segment of the esophagus and the rectum in a comparison experiment is small, but due to the influence of factors such as cerumen, the curvature of the ear canal and the like, the temperature obtained by the mode is usually the tympanic temperature instead of the tympanic membrane temperature; environmental and facial muscle activity can affect the tympanic temperature, making it deviate from the tympanic temperature to some extent, plus the same lack of long-term, real-time monitoring features.
In order to avoid the above problems, non-invasive methods of measuring body temperature have been proposed since the 70's of the 20 th century. There are mainly zero heat flow technology, single channel heat flow technology and dual channel heat flow technology. The current mainstream single-channel heat flow technology temperature measuring method is to place two precise temperature measuring components on two sides of a heat poor conductor for measuring the size of heat flow flowing into the heat poor conductor from skin and substituting the heat flow into a corresponding formula to obtain the corresponding core temperature of a human body. It is also usually covered on the outside with a thermal insulation material to insulate the external temperature from the heat flow. A schematic diagram of a typical single channel heat flow temperature probe is shown in figure 1.
The establishment of the single channel heat flow model is based on the assumption of one-dimensional steady-state heat conduction without a heat source. Heat conduction is a process of transition in nature, and, like other processes of transition in nature, such as the transfer of electricity, can be attributed to the amount of process transition-the process 'power/process resistance, expressed in electricity as ohm's law, i.e. the transfer of electricity
Figure BDA0002852100940000021
The temperature difference between the core temperature Tc and the probe causes heat to flow from the deep region beneath the skin and bones of the body to the body surface and then to the probe, T2And T1The temperature is distributed at the upper side and the lower side of the poor heat conductor of the heat flow channel, the thermal resistance of the probe is expressed as R, the thermal resistance of the skin and the skeleton of the human body is expressed as Rs, and based on the assumption, the heat flow balance formula in the single channel is as follows:
Figure BDA0002852100940000022
the formula of the core temperature of the human body can be obtained as follows:
Figure BDA0002852100940000023
wherein
Figure BDA0002852100940000024
Is the characteristic coefficient of the probe.
From the above reasoning, it can be seen that the existing single-channel heat flow technology is based on one-dimensional steady-state heat conduction, and therefore it is important to obtain a stable and proper heat flow channel. The existing single-channel heat flow sensor also has the problems of slow establishment time, horizontal heat flow and environmental disturbance in the establishment of the heat flow channel.
Disclosure of Invention
The invention aims to provide a core temperature measuring probe with a sandwich structure and a method thereof, which are used for solving the problem that heat flow is slowly established and is easily interfered in a single-channel heat flow technology.
In order to achieve the purpose, the invention provides the following scheme:
a core temperature measuring probe with a sandwich structure comprises an outer layer heat insulation structure and an inner layer sandwich structure which is wrapped by the outer layer heat insulation structure in a ring manner;
the inner-layer sandwich structure sequentially comprises a measuring module, a radiation isolation layer and a good heat conduction layer from bottom to top; the radiation isolation layer is arranged between the radiation isolation layer and the good heat conduction layer, and the radiation isolation layer is arranged between the radiation isolation layer and the good heat conduction layer;
the measuring module comprises a circuit structure, and a temperature sensor and a heat flow sensor which are arranged on the circuit structure, wherein the temperature sensor and the heat flow sensor are both in contact with the heat-conducting pouring material.
Optionally, the measurement module further comprises an external temperature sensor; the outer temperature sensor is arranged between the radiation isolation layer and the good heat conduction layer and is fixed below the good heat conduction layer through adhesive glue.
Optionally, the measurement module further comprises a biocompatible layer; the biocompatible layer is disposed under the circuit structure and is for adhesively coupling the skin of the human body to the core temperature measurement probe.
Optionally, the heat-conducting potting material is cured and then adhesively connected to the outer heat-insulating structure, the radiation isolation layer, and the circuit structure, respectively, and the good heat-conducting layer, the radiation isolation layer, and the circuit structure are partially embedded in the outer heat-insulating structure.
Optionally, the heat flow sensor and the temperature sensor are fixed on the circuit structure by welding.
Optionally, the radiation isolation layer is made of metal aluminum, the good heat conduction layer is made of metal copper, and the outer layer heat insulation structure is made of heat insulation foam; the biocompatible layer is a biocompatible colloid.
Optionally, the thermally conductive potting material is biocompatible.
Optionally, the thermal conductivity of the air is less than or equal to 0.0311W/(m · K).
A core temperature measurement method applied to a core temperature measurement probe of a sandwich structure, comprising:
placing a core temperature measuring probe on the surface of the skin of a human body to acquire a first temperature acquired by a temperature sensor, a second temperature acquired by an outer temperature sensor and heat flow of a heat flow sensor;
determining an environment compensation coefficient;
and calculating the core temperature of the human body based on the first temperature, the second temperature, the heat flow and the environment compensation coefficient.
Optionally, calculating the core temperature of the human body based on the first temperature, the second temperature, the heat flow and the environmental compensation coefficient specifically includes:
according to the formula Tc=Rs*UHFS+TS+m*TaCalculating the core temperature of the human body;
wherein, TSIs a first temperature; t isaIs a second temperature; m is an environment compensation coefficient; u shapeHFSIs a heat flow; t iscIs the core temperature of the human body, RsIs an individual difference coefficient.
According to the specific embodiment provided by the invention, the invention discloses the following technical effects:
the invention provides a core temperature measuring probe with a sandwich structure and a method thereof, wherein horizontal heat flow is reduced as much as possible through an outer-layer heat insulation structure; a proper heat flow channel is quickly established through the heat flow sensor and the temperature sensor in the inner-layer sandwich structure; the environmental disturbance can be effectively shielded by the thin air layer and the radiation isolation layer. Therefore, the core temperature measuring probe with the sandwich structure and the method thereof can solve the problem that the heat flow is slowly established and is easily interfered in the single-channel heat flow technology.
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In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings needed to be used in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without inventive exercise.
FIG. 1 is a schematic diagram of a typical prior art single channel heat flow temperature probe;
FIG. 2 is a schematic structural view of a core temperature measurement probe of a sandwich structure according to the present invention;
FIG. 3 is a schematic diagram of the use of a core temperature measurement probe of the sandwich construction of the present invention;
FIG. 4 is a flow chart of a core temperature measurement method of a sandwich structure according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The invention aims to provide a core temperature measuring probe with a sandwich structure and a method thereof, which are used for solving the problem that heat flow is slowly established and is easily interfered in a single-channel heat flow technology.
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in further detail below.
Example one
As shown in fig. 2, the core temperature measuring probe with a sandwich structure provided in this embodiment includes an outer layer heat insulating structure 1 and an inner layer sandwich structure that is wrapped with the outer layer heat insulating structure 1 in a circular ring manner.
The material of the outer layer heat insulation structure 1 is heat insulation foam, so that the environment temperature in the horizontal direction can be insulated, and the horizontal heat flow can be well reduced due to the small-volume horizontal scale. According to simulation results, the horizontal dimension can have an optimal value below the dimension with the radius of 3mm, and the radius of the actual horizontal dimension is 2.6 mm.
The inner-layer sandwich type structure sequentially comprises a measuring module, a radiation isolation layer 2 and a good heat conduction layer 3 from bottom to top; wherein, be heat conduction filling material 4 between measurement module and radiation isolation layer 3, be the air between radiation isolation layer 2 and the good heat-conducting layer 3. The measuring module comprises a circuit structure 5 and a temperature sensor 6 and a heat flow sensor 7 arranged on the circuit structure 5, and both the temperature sensor 6 and the heat flow sensor 7 are in contact with the heat conducting potting material 4. The sandwich structure of the inner layer can effectively shield the environmental disturbance and quickly and effectively establish the heat flow channel in the vertical direction
The heat flow sensor 7 (response time: 0.7s) and the temperature sensor 6 are responsible for measuring the heat flow and temperature flowing into the core temperature measuring probe; the heat flow sensor 7 and the temperature sensor 6 are fixed on the circuit structure 5 by welding.
The heat-conducting potting material 4 is adhesively connected with the heat-insulating foam after being cured, and the good heat-conducting layer 3, the radiation isolation layer 2 and the circuit structure 5 are partially embedded in the heat-insulating foam and are connected with the heat-insulating foam in an embedded manner, i.e. the good heat-conducting layer 3, the radiation isolation layer 2 and the circuit structure 5 are partially embedded in the outer heat-insulating structure 1.
As a preferred embodiment, the present embodiment provides a measuring module further comprising an external temperature sensor 8 and a biocompatible layer 9; the outer temperature sensor 8 is arranged between the radiation isolation layer 5 and the good heat conduction layer 3 and is fixed under the good heat conduction layer 3 through adhesive glue, the outer temperature sensor 8 measures the reference change of the external temperature to compensate the temperature reference, namely the influence of the environmental temperature can be compensated through the outer temperature sensor 8; a biocompatible layer 9 is arranged under the circuit structure 5 and the biocompatible layer 9 is used to adhesively connect the human skin with the core temperature measuring probe and to provide a good thermal contact, being a consumable.
As a preferred embodiment, the thermally conductive potting material 4 provided in this embodiment is PDMS, which has good biocompatibility, and the high thermal conductivity enables the vertical thermal flow channel to be established quickly and effectively. The initial state of the heat-conducting filling material 4 is liquid, the heat-conducting filling material 4 is filled into the core temperature measuring probe to be heated and then cured, and the heat-conducting filling material 4 is connected with the outer-layer heat-insulating structure 1, the radiation isolation layer 2 and the circuit structure 5 by virtue of viscosity.
As a preferred embodiment, the material of the radiation isolation layer 2 provided in this embodiment is metal aluminum, which can effectively shield the thermal radiation propagation path, but does not prevent the heat from being conducted and transferred vertically through the heat conductive potting material 4. Radiation isolation layer 2 relies on viscidity to be connected with heat conduction potting compound 4, and radiation isolation layer 2 relies on embedding structure to be connected with outer adiabatic structure 1.
As a preferable embodiment, the thermal conductivity of the rarefied air provided by the present embodiment is not more than 0.0311W/(m · K), and the rarefied air and the radiation isolation layer 2 act together to buffer the change of the external ambient temperature, so as to effectively shield the environmental disturbance. The rarefied air forms a closed cavity by the radiation isolation layer 2, the outer layer heat insulation structure 1 and the good heat conduction layer 3 and is sealed in the core temperature measuring probe.
As a preferred embodiment, the material of the good thermal conductive layer 3 provided in this embodiment is metal copper, which can prevent heat accumulation. The good heat conduction layer 3 and the outer layer heat insulation structure 1 are connected by an embedded structure and are fixed by auxiliary sealant.
The core temperature measuring probe with a sandwich structure disclosed by the embodiment comprises an outer-layer heat insulation structure and an inner-layer sandwich structure: the outer layer heat insulation structure is made of heat insulation materials, namely heat insulation foam and is used for reducing horizontal heat flux as much as possible; the inner-layer sandwich structure comprises a measuring module, a heat-conducting filling material, a radiation isolation layer, air and a good heat-conducting layer from bottom to top, and can isolate external air disturbance and establish a proper heat flow channel; the measuring module comprises a temperature sensor, an external temperature sensor, a heat flow sensor and a biocompatible layer which is biocompatible with the human body, and is responsible for measuring the temperature and the heat flow of the human body. The core temperature measuring probe with the sandwich structure disclosed by the embodiment is improved aiming at the problems of slow establishment of heat flux, external disturbance and horizontal heat flux in the single-channel heat flow technology; meanwhile, a heat flow sensor is added in the measuring module, and improvement is performed on unstable heat flow and instantaneity in a single-channel heat flow technology.
Example two
The core temperature prediction model is built based on the one-dimensional steady-state heat conduction assumption of the pyrogen-free source. Heat conduction is a process of transition in nature, and, like other processes of transition in nature, such as the transfer of electricity, can be attributed to the amount of process transition, i.e., the kinetic/process resistance of the process, expressed in electricity as ohm's law, i.e., ohm's law
Figure BDA0002852100940000071
The heat caused by the temperature difference between the core temperature Tc and the core temperature measuring probe flows from the deep region under the skin and bone of the human body to the body surface and then to the core temperature measuring probe, T2And T1Is the temperature distributed on the upper and lower sides of the heat-conducting perfusion material of the heat-flow channel, the heat resistance of the heat-conducting perfusion material is expressed as R, and the heat resistance of the skin and the skeleton of the human body is expressed as Rs
Based on the above assumptions, the heat flow balance in the heat flow channel is formulated as:
Figure BDA0002852100940000072
the formula of the core temperature of the human body can be obtained as follows:
Figure BDA0002852100940000073
the relationship between thermal resistance and thermal conductivity is
Figure BDA0002852100940000074
Wherein R may pass
Figure BDA0002852100940000075
Is obtained theoreticallyCan be calibrated experimentally.
Wherein, R is the thermal resistance of the heat-conducting pouring material, L is the distance between the upper temperature point and the lower temperature point of the heat-conducting pouring material, lambda is the heat conductivity coefficient of the heat-conducting pouring material, and S is the sectional area of the heat-conducting pouring material. Further, it is possible to obtain:
Figure BDA0002852100940000081
wherein the value U of the heat flow sensorHFSTemperature T at the skin, obtained by a heat flow sensorSObtainable by a temperature sensor, RsThe individual difference coefficient can be obtained by experimental calibration.
Simultaneously because of there is inevitable temperature difference in the summer winter etc. because of the external temperature, cause the loss in the heat flow channel, consequently need carry out corresponding compensation, this embodiment utilizes self-control thermostated container, changes ambient temperature under the simulation experiment environment, and the winter and summer of simulation environment changes, has confirmed compensation coefficient m, and the formula that obtains human core temperature by core temperature measurement probe finally is: t isc=Rs*UHFS+TS+m*Ta
Wherein the value U of the heat flow sensorHFSTemperature T at the skin, obtained by a heat flow sensorSCan be obtained by a temperature sensor, TaThe core temperature T of the human body is obtained by an external temperature sensor and calculated by a formulac. FIG. 3 is a schematic diagram of the core temperature measurement probe of the sandwich structure of the present invention in use.
Based on the content, the core temperature measurement method provided by the present embodiment includes the steps shown in fig. 4.
Step 101: placing a core temperature measuring probe on the surface of the skin of a human body to acquire a first temperature acquired by a temperature sensor, a second temperature acquired by an outer temperature sensor and heat flow of a heat flow sensor;
step 102: an environmental compensation factor is determined.
Step 103: based on the first temperature, the second temperature, the heat flow, and the environmental compensation factorAnd calculating the core temperature of the human body. The calculation formula is Tc=Rs*UHFS+TS+m*Ta
Wherein, TSIs a first temperature; t isaIs a second temperature; m is an environment compensation coefficient and is a specific numerical value; u shapeHFSIs a heat flow; t iscIs the core temperature of the human body.
The problem that the establishment time of the existing single-channel heat flow sensor is slow exists in the establishment of a heat flow channel, and a stable one-dimensional heat flow channel can be established only after the heat quantity passes through a poor heat conductor and reaches the balance of the upper end and the lower end. The invention adopts the mode of combining the heat flow sensor and the temperature sensor, utilizes the measuring module (the response time of the heat flow sensor: 0.7s) of the bottom layer to solve the problems, improves the upper layer structure and can accelerate the heat transfer by using the heat-conducting perfusion material.
The traditional single-channel heat flow sensor has heat flow in the horizontal direction because a large sectional area is needed to ensure the temperature difference of the upper temperature sensor and the lower temperature sensor. The measuring module adopted by the invention is arranged on the bottom layer, so that heat flow transfer can be ensured by using a heat conduction filling material with smaller volume, and meanwhile, the heat flow in the horizontal direction can be reduced to the greatest extent by using an outer layer heat insulation structure and a radiation isolation layer.
Meanwhile, the single-channel heat flow sensor in the prior art has the problem of environmental disturbance on a heat flow channel due to the fact that the outermost layer structure is a single heat-insulating material. The core temperature measuring probe with the sandwich structure is designed, and the radiation isolation layer can effectively shield radiation, but cannot prevent vertical conduction of heat; the outermost good heat conduction layer is made of metal, so that heat accumulation is prevented, air can be still and tightly sealed in the core temperature measuring probe, and the thermal conductivity of the still air is only 0.0311W/(m.K). The two buffer effects play a role in buffering the disturbance of the ambient temperature, and can effectively shield the ambient disturbance. Meanwhile, the external temperature sensor can measure the reference change of the external temperature to compensate to a certain degree.
The embodiments in the present description are described in a progressive manner, each embodiment focuses on differences from other embodiments, and the same and similar parts among the embodiments are referred to each other.
The principles and embodiments of the present invention have been described herein using specific examples, which are provided only to help understand the method and the core concept of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, the specific embodiments and the application range may be changed. In view of the above, the present disclosure should not be construed as limiting the invention.

Claims (10)

1.一种夹心式结构的核心温度测量探头,其特征在于,包括外层绝热结构以及用所述外层绝热结构以圆环式包裹的内层夹心式结构;1. A core temperature measuring probe of a sandwich structure, characterized in that, comprising an outer layer thermal insulation structure and an inner layer sandwich type structure wrapped in a ring type with the outer layer thermal insulation structure; 所述内层夹心式结构从下至上依次包括测量模块、辐射隔离层以及良导热层;其中,所述测量模块与所述辐射隔离层之间为导热灌注材料,所述辐射隔离层与所述良导热层之间为空气;The inner layer sandwich structure includes a measurement module, a radiation isolation layer and a good thermal conductivity layer in sequence from bottom to top; wherein, a thermally conductive pouring material is formed between the measurement module and the radiation isolation layer, and the radiation isolation layer is connected to the radiation isolation layer. There is air between the good thermal conductivity layers; 所述测量模块包括电路结构以及设置在所述电路结构上的温度传感器和热流传感器,且所述温度传感器和所述热流传感器均与所述导热灌注材料接触。The measurement module includes a circuit structure and a temperature sensor and a heat flow sensor disposed on the circuit structure, and both the temperature sensor and the heat flow sensor are in contact with the thermally conductive potting material. 2.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述测量模块还包括外温度传感器;所述外温度传感器设置在所述辐射隔离层与所述良导热层之间且通过粘性胶固定于所述良导热层下。2 . The core temperature measurement probe of a sandwich structure according to claim 1 , wherein the measurement module further comprises an external temperature sensor; the external temperature sensor is arranged between the radiation isolation layer and the good temperature. 3 . between the thermally conductive layers and fixed under the good thermally conductive layer by adhesive glue. 3.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述测量模块还包括生物相容性层;所述生物相容性层设置在所述电路结构下且所述生物相容性层用于粘性连接人体皮肤与核心温度测量探头。3 . The core temperature measurement probe of a sandwich structure according to claim 1 , wherein the measurement module further comprises a biocompatibility layer; the biocompatibility layer is arranged under the circuit structure. 4 . And the biocompatible layer is used for adhesively connecting the human skin and the core temperature measuring probe. 4.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述导热灌注材料固化后分别与所述外层绝热结构、所述辐射隔离层、所述电路结构粘性连接,所述良导热层、所述辐射隔离层以及所述电路结构部分嵌入在所述外层绝热结构上。4 . The core temperature measuring probe of a sandwich structure according to claim 1 , wherein the thermally conductive pouring material is cured with the outer heat insulating structure, the radiation isolation layer, and the circuit structure, respectively. 5 . Adhesive connection, the good thermal conductivity layer, the radiation isolation layer and the circuit structure are partially embedded on the outer insulating structure. 5.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述热流传感器与所述温度传感器均通过焊接方式固定于所述电路结构上。5 . The core temperature measurement probe of a sandwich structure according to claim 1 , wherein the heat flow sensor and the temperature sensor are both fixed on the circuit structure by welding. 6 . 6.根据权利要求3所述的一种夹心式结构的核心温度测量探头,其特征在于,所述辐射隔离层的材料为金属铝,所述良导热层的材料为金属铜,所述外层绝热结构的材料为绝热泡沫;所述生物相容性层为生物相容性胶体。6 . The core temperature measurement probe of a sandwich structure according to claim 3 , wherein the material of the radiation isolation layer is metal aluminum, the material of the good thermal conductivity layer is metal copper, and the outer layer is made of metal. 7 . The material of the thermal insulation structure is thermal insulation foam; the biocompatible layer is a biocompatible colloid. 7.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述导热灌注材料具有生物相容性。7 . The core temperature measuring probe of a sandwich structure according to claim 1 , wherein the thermally conductive pouring material has biocompatibility. 8 . 8.根据权利要求1所述的一种夹心式结构的核心温度测量探头,其特征在于,所述空气的导热率小于等于0.0311W/(m·K)。8 . The core temperature measurement probe of a sandwich structure according to claim 1 , wherein the thermal conductivity of the air is less than or equal to 0.0311 W/(m·K). 9 . 9.一种核心温度测量方法,其特征在于,所述核心温度测量方法应用于权利要求2所述的一种夹心式结构的核心温度测量探头,包括:9. A core temperature measurement method, wherein the core temperature measurement method is applied to a core temperature measurement probe of a sandwich structure according to claim 2, comprising: 将核心温度测量探头放置在人体皮肤表面以获取温度传感器采集的第一温度、外温度传感器采集的第二温度以及热流传感器的热流;placing the core temperature measurement probe on the surface of the human skin to obtain the first temperature collected by the temperature sensor, the second temperature collected by the external temperature sensor, and the heat flow of the heat flow sensor; 确定环境补偿系数;Determine the environmental compensation coefficient; 基于所述第一温度、所述第二温度、所述热流以及所述环境补偿系数,计算人体核心温度。A human core temperature is calculated based on the first temperature, the second temperature, the heat flow, and the environmental compensation factor. 10.根据权利要求9所述的一种核心温度测量方法,其特征在于,所述基于所述第一温度、所述第二温度、所述热流以及所述环境补偿系数,计算人体核心温度,具体包括:10 . The method for measuring core temperature according to claim 9 , wherein, calculating the core temperature of a human body based on the first temperature, the second temperature, the heat flow and the environmental compensation coefficient, 10 . Specifically include: 根据公式Tc=Rs*UHFS+TS+m*Ta计算人体核心温度;Calculate the core temperature of the human body according to the formula T c =R s *U HFS +T S +m*T a ; 其中,TS为第一温度;Ta为第二温度;m为环境补偿系数;UHFS为热流;Tc为人体核心温度,Rs为个体性差异系数。Among them, T S is the first temperature; T a is the second temperature; m is the environmental compensation coefficient; U HFS is the heat flow; T c is the core temperature of the human body, and R s is the individual difference coefficient.
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