CN112675064B

CN112675064B - Anti-irritation and hair-brightening composition and preparation method and application thereof

Info

Publication number: CN112675064B
Application number: CN202011641089.1A
Authority: CN
Inventors: 马潮生; 肖瑞光; 惠敏
Original assignee: Zhaoqing Dicai Daily Chemical Science And Technology Co ltd
Current assignee: Zhaoqing Dicai Daily Chemical Science And Technology Co ltd
Priority date: 2020-12-31
Filing date: 2020-12-31
Publication date: 2023-02-28
Anticipated expiration: 2040-12-31
Also published as: CN112675064A

Abstract

The invention provides an anti-irritation and hair-brightening composition, and a preparation method and application thereof. The anti-irritation and hair-brightening composition comprises the following components in parts by weight: 0.01-10 parts of trehalose; 0.01 to 15 parts of royal jelly extract. The anti-irritation and hair-brightening composition provided by the invention utilizes the synergistic effect of the trehalose and the royal jelly extract, can obviously reduce the irritation of the hair dye to the skin on the basis of not changing the hair dyeing effect, and also has the effects of preserving moisture and brightening hair.

Description

Anti-irritation and hair-brightening composition and preparation method and application thereof

Technical Field

The invention belongs to the technical field of cosmetics, and particularly relates to an anti-irritation and hair-brightening composition as well as a preparation method and application thereof.

Background

With the acceleration of the pace of life, people pursue fashion more and more according to the hair dressing, and more people choose to change the color of the hair so as to obtain a new mood and improve the quality of life of the people. However, with frequent hair management, people have higher and higher dependence on hair dyeing, and the use of inferior hair dye or frequent use of hair dye causes certain damage and influence on hair, so that the hair becomes frightened and withered, the moisture is easy to break, and the hair loss is serious; even on the scalp, the irritation of alkalinity and oxidizability of the material body to the scalp skin seriously affects the scalp health of consumers, causes sensitive pruritus of the scalp, dandruff breeding and a series of hair and scalp problems.

Hair dyes are hair products capable of changing hair color, and generally include disposable hair dyes, semi-permanent hair dyes and permanent hair dyes. The permanent hair dye is mainly oxidation-reduction hair dye, and generally has two dosage forms, namely a hair dyeing agent No. 1 (or agent A) and a hair dyeing agent No. 2 (or agent B). The hair dyeing agent No. 1 mainly contains coloring agent (intermediate and coupler) for determining new color and alkali agent, and the hair dyeing agent No. 2 mainly contains oxidizing agent and pH stabilizer. The swelling effect of the alkaline agent on the hair causes the scales of the hair to be damaged, withered and dry, the oxidation effect of the oxidizing agent has oxidation effect on the skin, the skin is pricked, and the phenomena of itching and allergy can be caused by the direct contact of the coloring agent and the skin, so the experience feeling and the health of consumers are seriously influenced.

For example, patents CN109498502A and CN111346037A have studied how to protect hair color, but the research on such products is still relatively small.

Therefore, there is a need to develop a mild and safe hair dyeing product which has little irritation to the scalp and improves the glossiness of the hair.

Disclosure of Invention

The invention aims to overcome the defect that hair dyes have great stimulation to scalp in the prior art, and provides an anti-stimulation and hair-brightening composition. The anti-irritation and hair-brightening composition provided by the invention utilizes the synergistic effect of the trehalose and the royal jelly extract, can obviously reduce the irritation of the hair dye to the skin on the basis of not changing the hair dyeing effect, and also has the effects of moisturizing and brightening hair.

It is another object of the present invention to provide a method for preparing the anti-irritant, hair-lightening composition.

It is another object of the present invention to provide the use of the anti-irritant, hair-lightening composition in the preparation of hair dyes.

In order to achieve the purpose, the invention adopts the following technical scheme:

an anti-irritation and hair-brightening composition comprises the following components in parts by weight:

0.01 to 10 parts of trehalose;

0.01 to 15 parts of royal jelly extract.

Trehalose is a safe, mild and reliable multi-effect natural saccharide, is disaccharide formed by dehydration condensation of two alpha-D-glucopyranosyl groups, generally contains two bound waters, and has the following structural formula:

trehalose is non-reducing sugar, is easy to dissolve in water, is acid and alkali resistant, has super strong stress resistance, can be stable under severe conditions, and can resist high temperature of 180 ℃, low temperature of-200 ℃ and radiation 1000 times higher than human lethal dose; when the sugar is dehydrated to 3 percent, the sugar can survive for 1 century and is known as 'sugar of life'.

The trehalose contains a plurality of hydroxyl groups (-OH), and can be combined with the acetylcholine of the phospholipid bilayer in cells through hydrogen bond action, so that the phospholipid bilayer is not easy to hydrolyze and separate, the scalp is promoted to be strongly resistant to the damage of the external severe environment, the scalp irritation is small in the hair dyeing process, and the hair is dyed mildly in the whole process. The polyhydroxy characteristic of the trehalose can be combined with the protein of the cell phospholipid bilayer to form stable glycoprotein, so that the damaged scalp can be quickly and effectively healed, a new 'defense wall' is given to the scalp, and the anti-stimulation effect of the scalp on external severe conditions is enhanced; the trehalose molecules are small, and can efficiently permeate into cells to protect the integrity and stability of cell DNA, so that the cells are promoted to be metabolized normally, an immune system is strengthened, and the resistance to the outside is improved.

The polyhydroxy in the trehalose endows scalp with good antioxidation, inhibits scalp oil oxidative decomposition, promotes normal oil metabolism, controls oil-water balance of scalp, and simultaneously inhibits peculiar smell caused by oil decomposition. The polyhydroxy characteristic of the trehalose endows the hair with an excellent moisturizing effect through the multi-level, wide-range and multi-type Van der Waals effect, a three-dimensional net-shaped film is formed on the hair or scalp, the water is effectively locked and moisturized, the humidity of the hair and scalp is kept, the hair is endowed with good luster, the oil-water balance of the scalp is kept, and the scurf is prevented from breeding.

The royal jelly extract contains natural flavonoid, royal jelly acid, natural collagen, amino acid micromolecule prepared by enzymolysis of polysaccharide, and the like. The natural flavonoids and the royal jelly acid have the functions of controlling oil, relieving itching and inhibiting bacteria, can obviously relieve the irritation brought by the formula, reduce the pricking feeling of the hair dye on the scalp, balance the growth of microorganisms, maintain the good ecological environment of the scalp and prevent the scurf from breeding. The hydrolyzed amino acid micromolecules of natural collagen and various polysaccharides can promote the production of scalp collagen, endow the scalp with good anti-irritation effect, simultaneously have good oxidation resistance and multi-potential state, can reduce the tingling sensation brought by the hair dyeing No. 2 color developing agent, and has obvious irritation reduction effect on alkaline agents, acid agents, other electrovalence surface active substances and the like in the formula.

The anti-irritation hair-brightening hair dyeing composition has the effects of protecting, defending, improving and gaining by supplementing natural saccharides, natural flavonoids, natural amino acids, royal jelly acid and other substances to the scalp of hair, and achieves the anti-irritation hair-brightening effect. The composition is combined with a scalp phospholipid bilayer through Van der Waals effect to form an excellent skin barrier, and scalp immunity is promoted through diffusion effect, so that the tingling feeling brought by the formula components in the hair dyeing process is remarkably reduced, the effects of whole-course mild, no stimulation and no allergy hair dyeing are achieved, and the scalp health is protected; through the characteristics of oxidation resistance and the like, the growth of microorganisms is inhibited, and the oxidative decomposition of grease is inhibited, so that the ecological environment of the scalp is improved, the oil-water balance is controlled, and the breeding of dandruff is prevented; the three-dimensional netted water locking film is formed through the action of hydrogen bonds, so that the skin and the hair can breathe freely and fully supplement water, the ecological balance of the scalp environment is achieved, and meanwhile, the hair has excellent glossiness. Compared with the conventional hair dye, the hair dye has the advantages of having remarkable effects of resisting stimulation and brightening hair, well preventing the scalp health problem after dyeing, having a synergistic effect among various components in the composition, and enabling each component to exert the most optimal effect, thereby achieving the effect of resisting stimulation and brightening hair.

Preferably, the anti-irritation and hair-lightening composition comprises the following components in parts by weight:

1 to 6 parts of trehalose;

0.2 to 3 parts of royal jelly extract.

Further preferably, the anti-irritation and hair-lightening composition comprises the following components in parts by weight:

3 parts of trehalose;

1 part of royal jelly extract.

The preparation method of the anti-irritation and hair-brightening composition is characterized by comprising the following steps: mixing trehalose and Lac Regis Apis extract to obtain the composition with anti-irritation and hair-brightening effects.

Preferably, the temperature for mixing is 50 to 70 ℃.

Preferably, the mixing time is 1 to 10min.

The use of the above anti-irritant, hair-lightening composition in the preparation of hair dyes is also within the scope of the invention.

A hair dye is prepared from the above anti-irritation and hair-brightening composition.

Preferably, the hair dye consists of the following components in percentage by mass:

1 to 6wt% of the anti-irritation and hair-lightening composition;

the balance of hair dye matrix.

Preferably, the hair dye matrix consists of the following components in percentage by mass:

5.0 to 10.0 percent of an excipient thickener; 0.5 to 4.0 percent of lubricant; 1.5 to 3.0 percent of nonionic emulsifier; 0.5 to 1.5 percent of conditioner for hair; 3.0 to 6.0 percent of humectant; 0.1 to 0.8 percent of chelating agent; 0.1 to 0.3 percent of oxidation retarder; 0.1 to 5 percent of coloring agent; 0.1 to 0.5 percent of antioxidant; 5.5 to 10.5 percent of alkaline agent; 0.5 to 1.0 percent of essence and the balance of water.

Preferably, the fat-imparting thickening agent is one or a combination of more of cetyl alcohol, stearyl alcohol, cetostearyl alcohol, lauryl alcohol, myristyl alcohol or behenyl alcohol.

Preferably, the lubricant is one or a combination of several of polydimethylsiloxane, cyclohexasiloxane, cyclopentadimethylsiloxane, isopropyl myristate, isopropyl palmitate or oleic acid.

Preferably, the nonionic emulsifier is one or a combination of more of stearyl alcohol polyoxyethylene ether-21, steareth-3, lauryl alcohol polyoxyethylene ether-20, lauryl alcohol polyoxyethylene ether-25, lauryl alcohol polyoxyethylene ether-30, cetearyl alcohol polyoxyethylene ether-20 or oleyl alcohol polyether-25.

Preferably, the hair conditioner is one or a combination of several of lauryl trimethyl ammonium chloride, cetyl trimethyl ammonium chloride, stearyl trimethyl ammonium chloride, behenyl trimethyl ammonium chloride, polyquaternium-7, polyquaternium-22 or polyquaternium-37.

Preferably, the humectant is one or a combination of propylene glycol, glycerol, sorbitol or panthenol.

Preferably, the chelating agent is one or a combination of more of disodium EDTA, tetrasodium EDTA and hydroxyethyldiphosphonic acid.

Preferably, the oxidation retarder is one or a combination of phenyl methyl pyrazolone, 8-hydroxyquinoline sulfate and 8-hydroxyquinoline.

Preferably, the coloring agent is one or a combination of several of p-phenylenediamine, p-aminophenol, resorcinol, m-aminophenol, 2-amino-3-hydroxypyridine, 4-chlororesorcinol, toluene-2, 5-diamino sulfate, 4-amino-m-cresol or 2-methyl resorcinol.

Preferably, the antioxidant is one or a combination of more of anhydrous sodium sulfite, sodium metabisulfite, thioglycolic acid, ascorbic acid, sodium ascorbate or sodium erythorbate.

Preferably, the alkaline agent is one or a combination of more of ammonia water, monoethanolamine, triethanolamine, sodium hydroxide, potassium hydroxide or sodium silicate.

Preferably, the essence is one or a combination of more of orange flower essence, grape essence or coco essence.

Compared with the prior art, the invention has the following beneficial effects:

the composition obtained by compounding the trehalose and the royal jelly extract is added into the hair dye, the trehalose can act with skin molecules, so that the skin has better anti-irritation performance, meanwhile, polyhydroxy in the trehalose can inhibit scalp grease from oxidative decomposition, promote normal metabolism of grease, control oil-water balance of the scalp, increase scalp anti-irritation performance, and simultaneously have a moisturizing effect and brighten hair; the amino acid micromolecules in the royal jelly extract can promote the production of scalp collagen and endow the scalp with good anti-irritation effect. The two components have synergistic effect, so that the irritation of the hair dye to skin can be remarkably reduced on the basis of not changing the hair dyeing effect, and the effects of moisturizing and brightening hair can be realized.

Detailed Description

The invention is further illustrated by the following examples. These examples are intended to illustrate the invention and are not intended to limit the scope of the invention. Experimental procedures without specifying specific conditions in the examples below, generally according to conditions conventional in the art or as recommended by the manufacturer; the raw materials, reagents and the like used are, unless otherwise specified, those commercially available from the conventional markets and the like. Any insubstantial changes from the invention, including those variations and alterations made by those skilled in the art, are intended to be covered by the claims.

The raw materials selected in the examples and comparative examples of the present invention are as follows:

trehalose: vivisugar ^TM THS, available from the plum blossom Biotechnology group, inc.;

royal jelly extract: SUNRISE ^TM FW, available from Morri Biotechnology, inc., guangzhou.

Examples 1 to 5 and comparative examples 1 to 3

This example provides a series of anti-irritant and hair-lightening compositions, which were prepared by mixing trehalose and royal jelly extracts according to the formulation shown in table 1, and were designated as compositions A1 to A5 (examples) and compositions B1 to B2 (comparative examples).

TABLE 1 formulation (parts by weight) of each of the compositions of examples and comparative examples

	Example 1	Example 2	Example 3	Example 4	Example 5	Comparative example 1	Comparative example 2
								Trehalose	0.01	1	3	6	10	/	4
Royal jelly extract	15	3	1	0.2	0.01	4	/

Examples 6 to 13

This example provides a series of anti-irritant, hair lightening agents prepared from the above anti-irritant, hair lightening compositions. The hair dye was obtained by mixing a hair dye base with the anti-irritant, hair-lightening composition according to the formulation of table 2. The hair dye matrix consists of 5% of cetostearyl alcohol, 1% of polydimethylsiloxane, 2% of steareth-21, 3% of isopropyl myristate, 1% of stearyltrimethyl ammonium chloride, 5% of propylene glycol, 0.5% of disodium EDTA, 0.3% of phenyl methylpyrazolinone, 0.3% of sodium erythorbate, 0.2%, 0.3% of p-phenylenediamine, 0.5% of resorcinol, 0.1% of m-aminophenol, 0.5% of anhydrous sodium sulfite, 9% of ammonia water (25%), 0.5% of orange flower essence and the balance of water, wherein the total amount of the formula is calculated.

Table 2 Hair dye component content (mass percent:%)

Starting materials	Example 6	Example 7	Example 8	Example 9	Example 10	Example 11	Example 12	Example 13
									Composition A1	1	2	4	6	—
Composition A2	—	—	—	—	1
									Composition A3	—	—	—	—	—	1
Composition A4	—	—	—	—	—		1
									Composition A5	—	—	—	—	—		1
Hair dye base	Balance of	Balance of	Balance of	Balance of	Balance of	Balance of	Balance of	Allowance of

Comparative example 3

This comparative example differs from example 11 in that composition A3 was replaced with composition B1 lacking trehalose.

Comparative example 4

This comparative example differs from example 11 in that composition A3 was replaced with composition B2 lacking the royal jelly extract.

Comparative example 5

This comparative example is a dicolor hair color cream (champagne brown).

Performance test

The performances of the hair dyes provided in examples 6 to 13 and comparative examples 3 to 5 were tested by the following test methods.

1. Scalp irritation performance testing: selecting 50 volunteers for skin test, uniformly mixing 0.5 g of the prepared hair dye with 0.5 g of the hair dye No. 2 agent, coating the mixture on an arm for 30 minutes, standing for 30 minutes, recording the number of stabbing pain, and classifying into four grades including no stabbing pain, slight stabbing itching, obvious stabbing pain and large stabbing pain, wherein the test method is a sensory test.

2. Brightness: uniformly mixing the prepared hair dye and a hair dyeing agent 2 according to the ratio of 1. The dry color was measured by a spectrocolorimeter (CM-2600 d), and the value of L, which is larger, indicates brighter and better gloss, was measured.

The test results are shown in table 3:

TABLE 3 test results of hair dyes prepared in each example and comparative example

Note: the units of the numbers of the irritation test results in table 3 are: a human being.

The anti-irritation and hair-brightening hair dye prepared from the anti-irritation and hair-brightening composition provided by the embodiments of the invention can greatly reduce the irritation of the hair dye to the skin of a human body, has a synergistic effect between the two components, protects the scalp from being corroded and stabbed by the hair dye, ensures that the hair dye is safe for the human body, and provides the whole-process mild hair dyeing; in addition, the dyeing effect can be enhanced, the coloring is uniform, the glossiness of dyed hair is improved, the brightness of the dyeing effect is obviously increased, and the hair is brighter. If the selected anti-irritation and hair-brightening composition lacks certain components and further has weak synergistic effect (such as comparative examples 1 to 4), the itching and tingling feeling of the human body caused by the irritation of the hair dye body is obviously enhanced, and then the hair is frizzy and has obviously reduced brightness. Meanwhile, compared with the existing product (comparative example 5), the anti-irritation and hair-brightening hair dye has remarkable effects on reducing skin irritation and improving the glossiness of dyed hair.

It will be appreciated by those of ordinary skill in the art that the examples provided herein are intended to assist the reader in understanding the principles of the invention and are to be construed as being without limitation to such specifically recited examples and embodiments. Those skilled in the art can make various other specific changes and combinations based on the teachings of the present invention without departing from the spirit of the invention, and these changes and combinations are within the scope of the invention.

Claims

1. The hair dye is characterized by comprising the following components in percentage by mass:

1 to 6wt% of an anti-irritant, hair-lightening composition;

the balance of hair dye matrix;

the anti-irritation and hair-brightening composition comprises the following components in parts by weight:

0.01 to 10 portions of trehalose;

0.01 to 15 parts of royal jelly extract;

the hair dye matrix comprises the following components in parts by mass: 5.0 to 10.0 percent of fat-imparting thickening agent; 0.5 to 4.0 percent of lubricant; 1.5 to 3.0 percent of nonionic emulsifier; 0.5 to 1.5 percent of conditioner for hair; 3.0 to 6.0 percent of humectant; 0.1 to 0.8 percent of chelating agent; 0.1 to 0.3 percent of oxidation retarder; 0.1 to 5 percent of coloring agent; 0.1 to 0.5 percent of antioxidant; 5.5 to 10.5 percent of alkaline agent; 0.5 to 1.0 percent of essence and the balance of water.

2. The hair colorant of claim 1, wherein the anti-irritant, hair-lightening composition comprises the following components in parts by weight:

1 to 6 parts of trehalose;

0.2 to 3 parts of royal jelly extract.

3. The hair colorant of claim 1, wherein the anti-irritant, hair-lightening composition comprises the following components in parts by weight:

3 parts of trehalose;

1 part of royal jelly extract.

4. The hair dye as claimed in any one of claims 1 to 3, wherein the preparation method of the anti-irritation and hair-brightening composition comprises the following steps: mixing trehalose and Lac Regis Apis extract to obtain the composition with anti-irritation and hair-brightening effects.

5. The hair dye according to claim 4, wherein the temperature of mixing is 50 to 70 ℃.

6. The hair dye composition according to claim 4, wherein the mixing time is 1 to 10min.