CN112653219A

CN112653219A - Implantable medical device and system

Info

Publication number: CN112653219A
Application number: CN202011558912.2A
Authority: CN
Inventors: 李青峰; 宗升
Original assignee: Beijing Pins Medical Co Ltd
Current assignee: Beijing Pins Medical Co Ltd
Priority date: 2020-12-25
Filing date: 2020-12-25
Publication date: 2021-04-13

Abstract

The present invention provides an implantable medical device and system. The device includes a coil for receiving instructions and electrical energy; a voltage regulator capacitor unit, which can be set to a low-capacitance state or a high-capacitance state; When the coil receives a charging command, the voltage regulator capacitor unit is set to a high capacitance state, and the coil receives electrical energy to charge the battery; otherwise, the voltage regulator capacitor unit is set to a low capacitance state, and the voltage regulator capacitor unit is set to a low capacitance state through The coil receives the communication command.

Description

Implantable medical device and system

Technical Field

The invention relates to the field of electronic medical instruments, in particular to an implantable medical device and system.

Background

With the development of bluetooth communication technology and transcutaneous charging technology, bluetooth communication and wireless charging have gradually become standard configurations for active implantable medical devices. Bluetooth communication is used for data interaction of the in-vivo implanted device and the in-vitro program control device, wireless charging is used for charging a rechargeable battery of the in-vivo implanted device, and continuous use of the device is maintained.

Low standby power consumption is an important performance index of a rechargeable active implantable medical device, and determines shelf life, charging duration, long-term life and the like of the active implantable device. And the load is increased by adding wireless communication modules such as bluetooth in the implanted medical device. For the problem, some existing products reduce standby power consumption by extending a bluetooth broadcast interval (several tens of seconds), but cause the problem of overlong connection establishment time for the first time, and the situation is worse when communication interference exists. Some existing products adopt a mode (such as a signaling mode or a long-time magnet brushing mode) of turning off a Bluetooth module in a standby mode and waking up the Bluetooth by external conditions which are not easy to trigger by mistake, and then manually identify a Bluetooth address to establish connection, so that the convenience of operation is reduced.

Chinese patent document CN106777915A discloses a scheme using two communication modules, which uses a second short-distance communication module (internal body) with low standby power consumption, and wakes up the second long-distance communication module (internal body) and receives the connection information of the first long-distance communication module (external body) through the module. However, in implementing this embodiment, the implant device needs to add a second communication module, that is, two coils and an additional set of communication module are required to be disposed in the implant device, where one coil is used for wireless charging and the other coil is used for receiving instructions, which increases the difficulty of miniaturization design of the implant device and brings additional burden.

Disclosure of Invention

In view of the above, the present invention provides an implantable medical device comprising:

a coil for receiving commands and electrical energy;

a regulator capacitance unit settable to a low capacitance state or a high capacitance state;

and the controller is used for setting the voltage stabilizer capacitor unit to be in a high-capacitance state when receiving a charging instruction through the coil, receiving electric energy through the coil to charge the battery, and otherwise, setting the voltage stabilizer capacitor unit to be in a low-capacitance state and receiving a communication instruction through the coil.

Optionally, the apparatus further comprises a wireless communication unit; and when the controller receives a communication instruction through the coil, the controller starts the wireless communication unit to establish connection with the extracorporeal device.

Optionally, the wireless communication unit is a bluetooth communication unit; the coil is used for inducing a PPM signal sent by the in-vitro device, and the controller is used for demodulating the PPM signal to acquire Bluetooth connection information and awakening the Bluetooth communication unit to establish connection with the in-vitro device according to the Bluetooth connection information.

Optionally, the controller detects a time interval t between two adjacent falling edges of the voltage regulator output voltage V0, and parses the bluetooth connection information according to the length of the time interval t.

Alternatively, when T_LMin＜t＜T_LMaxWhen the data is read, the data is analyzed as data 0; when T is_HMin＜t＜T_HMaxWhen it is time, it is resolved as data 1, where T_HMin≥1.5T_LMax。

Optionally, the voltage regulator capacitance unit includes:

a variable filter capacitance unit comprising a first capacitor C1 and a second capacitor C2 connected in series, a first controlled switch connected in parallel with said second capacitor C2, wherein the capacitance value of the second capacitor C2 is much smaller than the capacitance value of the first capacitor C1;

a variable output capacitance unit comprising a third capacitor C3 and a fourth capacitor C4 in series, a second controlled switch in parallel with said fourth capacitor C4, wherein the capacitance value of the fourth capacitor C4 is much smaller than the capacitance value of the third capacitor C3.

Optionally, when the controller receives a charging instruction through the coil, the controller closes the first controlled switch and the second controlled switch to increase an equivalent capacitance value, and opens the first controlled switch and the second controlled switch when wireless charging is not performed, so as to decrease the equivalent capacitance value.

Optionally, the apparatus further includes a bleed-off resistor and a third controlled switch connected in series, and the controller turns off the third controlled switch when receiving a charging instruction through the coil; and when the wireless charging is not carried out, the third controlled switch is closed, so that the bleeder resistor and the coil are in a parallel state.

The invention also provides an implantable medical system, which comprises an extracorporeal device and the implantable medical device, wherein the extracorporeal device is used for sending a communication instruction and a charging instruction to the implantable medical device through a coil.

In order to adapt to the two purposes, the capacitor unit of the voltage stabilizer in the scheme comprises a low-capacitance state and a high-capacitance state, the controller sets the capacitor unit to be in the low-capacitance state in a default state, the time of rising edges and falling edges of voltage waveforms generated under the combined action of the coil and the voltage stabilizer is shortened, the communication rate of PPM is improved, and the controller sets the capacitor unit to be in the high-capacitance state when wireless charging is needed, so that the voltage stability of a charging loop is improved. The communication coil of this scheme has multiplexed the charging coil, awakens up wireless communication module when needs communicate through this mode, only needs to make less improvement to the electric capacity of stabiliser, need not increase extra coil or trigger device, has compared in prior art and has saved chargeable implanted medical device's space size.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings can be obtained by those skilled in the art without creative efforts.

FIG. 1 is a schematic view of an implantable medical system in an embodiment of the present invention;

FIG. 2 is a circuit block diagram of an implantable medical device in an embodiment of the present invention;

fig. 3 is a diagram illustrating a PPM communication protocol in an embodiment of the invention.

Detailed Description

The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and it should be understood that the described embodiments are some, but not all embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

In the description of the present invention, it should be noted that the terms "first", "second", and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance. In addition, the technical features involved in the different embodiments of the present invention described below may be combined with each other as long as they do not conflict with each other.

As shown in fig. 1, an embodiment of the present invention provides an implantable medical system, which includes an extracorporeal apparatus 2 and an implantable medical device 1. The extracorporeal device 2 is provided with a coil and a wireless communication unit, wherein the coil is used for sending a communication instruction and a charging instruction to the implanted medical apparatus 1; the wireless communication unit is used for transmitting data, such as transmitting control data for the implantable medical device 1, and receiving device status data transmitted by the implantable medical device 1, and the like.

The implanted medical device 1 is provided with a coil, a voltage stabilizer capacitor unit, a wireless communication unit, a controller and a rechargeable battery. The coil is used for receiving electric energy to charge the rechargeable battery and is also used for receiving instructions, the implantable medical device 1 of the embodiment only has one coil, namely the communication coil is multiplexed with the charging coil; the voltage stabilizer is used for adjusting a voltage signal induced by the coil; the wireless communication unit is used for transmitting data, such as transmitting device status data, receiving control data transmitted by the extracorporeal device, and the like.

When the coil of the implantable medical device 1 is used for wireless charging or receiving instructions, the controller sets the voltage stabilizer capacitor unit to different states. In particular, the voltage regulator capacitive unit includes a low capacitance state and a high capacitance state, and in a default state (e.g., the implantable medical device 1 provides a therapy function, is on standby, is initially powered on, etc.), the coil is configured to receive instructions. The coil communicates by a Pulse Position Modulation (PPM) signal, and the controller analyzes the command by detecting the output voltage of the voltage stabilizer. In order to improve the rising edge and the falling edge of the voltage waveform in PPM communication, the processor sets the capacitor unit of the voltage stabilizer to be in a low-capacitance state, so that the time of generating the rising edge and the falling edge of the voltage waveform under the combined action of the coil and the voltage stabilizer is reduced, the communication rate of PPM is improved, and when a communication instruction is obtained through analysis, the wireless communication unit is started to establish connection with the extracorporeal device 2 and transmit data; when the charging instruction is analyzed, the coil is used for receiving electric energy to charge the rechargeable battery, and the controller sets the voltage stabilizer capacitor unit to be in a high-capacitance state so as to improve the voltage stability of the charging loop.

In order to adapt to the two purposes, the voltage stabilizer capacitor unit in the scheme comprises a low-capacitance state and a high-capacitance state, the voltage stabilizer capacitor unit is set to be in the low-capacitance state by the controller in the default state, the voltage waveform generated under the combined action of the coil and the voltage stabilizer is improved, the processor can accurately receive and analyze the instruction, and the controller sets the voltage stabilizer to be in the high-capacitance state when wireless charging is needed, so that the voltage stability of a charging loop is improved. The communication coil of this scheme has multiplexed the charging coil, awakens up wireless communication module when needs communicate through this mode, only needs to make less improvement to the electric capacity of stabiliser, need not increase extra coil or trigger device, has compared in prior art and has saved chargeable implanted medical device's space size.

A preferred implantable medical device is described below with reference to fig. 2, and the implantable medical device in this embodiment is provided with a coil L2, an LDO (low dropout regulator), a variable filter capacitor unit, a variable output capacitor unit, a bluetooth communication unit, and an in vivo microcontroller. Specifically, the variable filter capacitance unit comprises a first capacitor C1 and a second capacitor C2 connected in series, and a first controlled switch S1 connected in parallel with a second capacitor C2, wherein the capacitance value of the second capacitor C2 is much smaller than that of the first capacitor C1, such as C2 ≦ C1/100, C1 ≦ 10uF, and C2 ≦ 0.1 uF. The variable output capacitance unit comprises a third capacitor C3 and a fourth capacitor C4 which are connected in series, and a second controlled switch S2 which is connected with the fourth capacitor C4 in parallel, wherein the capacitance value of the fourth capacitor C4 is far smaller than that of the third capacitor C3, such as C4 ≦ C3/100. In order to improve the safety, the device is also provided with a bleeder resistor R1 and a third controlled switch S3.

In the default state, the bluetooth communication unit (bluetooth communication module and bluetooth antenna) is in the off state, S1 and S2 are open, and S3 is closed. At the moment, the coil L2 is used for receiving an instruction, when the external device sends a charging instruction through the coil L1, the internal microcontroller obtains the instruction content through the analysis of the PPM demodulation module, S1 and S2 are closed, S3 is opened, C2 and C4 are in short circuit, C1 is reserved as a filter capacitor, C3 is reserved as an LDO output capacitor, the equivalent capacitance values of the filter capacitor and the LDO output capacitor are increased, and the voltage stability of the charging loop is improved. The battery BT is charged by the charge management control chip by transferring electric power through the coils L1 and L2.

When the extracorporeal device sends a communication command through the coil L1, the intracorporeal microcontroller obtains the command content through the analysis of the PPM demodulation module, the S1 and the S2 are disconnected, the S3 is closed, the C1 and the C2 are connected in series, the C3 and the C4 are connected in series, the equivalent capacitance values of the filter capacitor and the LDO output capacitor are reduced, and meanwhile, the bleeder resistor R1 is connected. The communication instructions may be used to wake up the bluetooth communication unit and may also include connection information, such as bluetooth address information, etc. The implanted medical device can then use the bluetooth communication unit to perform data interaction with the extracorporeal device, and the bluetooth communication unit is turned off when the turn-off condition is met.

The implantable medical device of this embodiment analyzes the command through a PPM signal, and fig. 3 is a schematic diagram of a PPM communication protocol. The controller of the extracorporeal device sends out a PPM control signal, an exciting coil L1 generates a discontinuous magnetic field, a coil L2 of the implanted medical device induces a discontinuous voltage signal, the output end VO of the LDO generates a voltage waveform, the controller detects the time interval t of two adjacent falling edges of V0, and the Bluetooth connection information is analyzed according to the length of the time interval t. Specifically, when T is_LMin＜t＜T_LMaxWhen the data is read, the data is analyzed as data 0; when T is_HMin＜t＜T_HMaxWhen it is time, it is resolved as data 1, where T_HMin≥1.5T_LMaxWhen t does not satisfy the foregoing condition, it is invalid data.

According to the preferred scheme, the implantable medical device closes the Bluetooth communication module in a default state to reduce load and save energy consumption, when a user needs to perform Bluetooth connection on the external equipment and the internal equipment, the external equipment can be attached to the skin and aligned to the internal equipment, the internal equipment receives a relatively brief instruction by using a coil and a PPM (pulse position modulation) communication protocol, the PPM communication of the scheme is a one-way communication working mode from the outside to the inside, when the communication instruction is received through the mode, the Bluetooth communication module is automatically awakened, the connection information of the external equipment can be transmitted, automatic Bluetooth connection between the inside and the outside of the body is achieved, and the convenience of wireless connection is improved on the basis of not increasing the size of the device.

As will be appreciated by one skilled in the art, embodiments of the present invention may be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment or an embodiment combining software and hardware aspects. Furthermore, the present invention may take the form of a computer program product embodied on one or more computer-usable storage media (including, but not limited to, disk storage, CD-ROM, optical storage, and the like) having computer-usable program code embodied therein.

The present invention is described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (systems), and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flow diagrams and/or block diagrams, and combinations of flows and/or blocks in the flow diagrams and/or block diagrams, can be implemented by computer program instructions. These computer program instructions may be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing apparatus to produce a machine, such that the instructions, which execute via the processor of the computer or other programmable data processing apparatus, create means for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.

These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including instruction means which implement the function specified in the flowchart flow or flows and/or block diagram block or blocks.

These computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified in the flowchart flow or flows and/or block diagram block or blocks.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.

Claims

1. An implantable medical device is characterized in that, comprising:

Coils for receiving commands and electrical energy;

Voltage regulator capacitor unit, which can be set to a low-capacitance state or a high-capacitance state;

a controller, configured to set the voltage regulator capacitor unit to a high-capacitance state when a charging command is received through the coil, and to charge the battery by receiving electrical energy through the coil, otherwise set the voltage regulator capacitor unit to a high-capacitance state In a low-capacitance state, a communication command is received through the coil.

2 . The implantable medical device according to claim 1 , wherein the device further comprises a wireless communication unit; when the controller receives a communication instruction through the coil, it turns on the wireless communication unit to communicate with the external body. 3 . The device establishes a connection.

3. The implantable medical device according to claim 2, wherein the wireless communication unit is a Bluetooth communication unit; the coil is used to sense the PPM signal sent by the external device, and the controller is used to demodulate the The PPM signal acquires the Bluetooth connection information, and wakes up the Bluetooth communication unit to establish a connection with the external device according to the Bluetooth connection information.

4. The implantable medical device according to claim 3, wherein the controller detects the time interval t between two adjacent falling edges of the output voltage V0 of the voltage stabilizer, and analyzes the time interval t according to the length of the time interval t. Bluetooth connection information.

5. The implantable medical device according to claim 4, wherein when T _LMin <t<T _LMax , it is parsed as data 0; when T _HMin <t<T _HMax , it is parsed as data 1, wherein T _HMin ≥ 1.5T _LMax .

6. The implantable medical device according to any one of claims 1-5, wherein the voltage regulator capacitor unit comprises:

The variable filter capacitor unit includes a first capacitor C1 and a second capacitor C2 connected in series, and a first controlled switch connected in parallel with the second capacitor C2, wherein the capacitance value of the second capacitor C2 is much smaller than that of the first capacitor C1 value;

The variable output capacitance unit includes a third capacitor C3 and a fourth capacitor C4 connected in series, and a second controlled switch connected in parallel with the fourth capacitor C4, wherein the capacitance value of the fourth capacitor C4 is much smaller than that of the third capacitor C3 value.

7 . The implantable medical device according to claim 6 , wherein the controller closes the first controlled switch and the second controlled switch when receiving a charging instruction through the coil. 8 . , so as to increase the equivalent capacitance value, and disconnect the first controlled switch and the second controlled switch when the wireless charging is not performed to reduce the equivalent capacitance value.

8 . The implantable medical device according to claim 6 , wherein the device further comprises a series-connected bleeder resistor and a third controlled switch, and the controller receives a charging instruction through the coil. 9 . , disconnecting the third controlled switch; closing the third controlled switch when wireless charging is not performed, so that the bleeder resistor and the coil are in a parallel state.

9. An implantable medical system, characterized in that it comprises an in vitro device and the implantable medical device according to any one of claims 1 to 8, wherein the in vitro device is used to send the implantable medical device to the implanted medical device through a coil. The device sends a communication command and a charging command.