CN112566572B - 用于神经的热阻断的系统和方法 - Google Patents
用于神经的热阻断的系统和方法 Download PDFInfo
- Publication number
- CN112566572B CN112566572B CN201980054662.8A CN201980054662A CN112566572B CN 112566572 B CN112566572 B CN 112566572B CN 201980054662 A CN201980054662 A CN 201980054662A CN 112566572 B CN112566572 B CN 112566572B
- Authority
- CN
- China
- Prior art keywords
- thermal energy
- nerve
- energy system
- temperature
- cooling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 210000005036 nerve Anatomy 0.000 title claims abstract description 230
- 238000000034 method Methods 0.000 title claims abstract description 27
- 230000000903 blocking effect Effects 0.000 title abstract description 26
- 238000010438 heat treatment Methods 0.000 claims abstract description 227
- 238000001816 cooling Methods 0.000 claims abstract description 160
- 239000012530 fluid Substances 0.000 claims description 143
- 208000002193 Pain Diseases 0.000 claims description 38
- 230000002441 reversible effect Effects 0.000 claims description 32
- 230000001939 inductive effect Effects 0.000 claims description 27
- 238000004891 communication Methods 0.000 claims description 23
- 238000012544 monitoring process Methods 0.000 claims description 17
- 239000012809 cooling fluid Substances 0.000 claims description 16
- 230000007246 mechanism Effects 0.000 claims description 10
- 230000005672 electromagnetic field Effects 0.000 claims description 6
- 230000007704 transition Effects 0.000 claims description 6
- 230000006698 induction Effects 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 4
- 239000000523 sample Substances 0.000 description 53
- 238000012546 transfer Methods 0.000 description 38
- 239000007943 implant Substances 0.000 description 33
- 239000000499 gel Substances 0.000 description 32
- 239000000463 material Substances 0.000 description 23
- 230000004044 response Effects 0.000 description 18
- 238000005057 refrigeration Methods 0.000 description 15
- 208000024891 symptom Diseases 0.000 description 14
- 230000036760 body temperature Effects 0.000 description 13
- 238000003780 insertion Methods 0.000 description 13
- 230000037431 insertion Effects 0.000 description 13
- 230000000694 effects Effects 0.000 description 11
- 238000002513 implantation Methods 0.000 description 11
- 239000011810 insulating material Substances 0.000 description 11
- 210000004369 blood Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 10
- 239000011248 coating agent Substances 0.000 description 10
- 238000000576 coating method Methods 0.000 description 10
- 230000036772 blood pressure Effects 0.000 description 9
- 230000036541 health Effects 0.000 description 9
- 230000036982 action potential Effects 0.000 description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 8
- 229910052760 oxygen Inorganic materials 0.000 description 8
- 239000001301 oxygen Substances 0.000 description 8
- 239000000126 substance Substances 0.000 description 8
- 210000004243 sweat Anatomy 0.000 description 8
- 210000001519 tissue Anatomy 0.000 description 8
- 230000007659 motor function Effects 0.000 description 7
- 230000007830 nerve conduction Effects 0.000 description 7
- 210000002569 neuron Anatomy 0.000 description 7
- 230000035945 sensitivity Effects 0.000 description 7
- 230000001953 sensory effect Effects 0.000 description 7
- 208000000094 Chronic Pain Diseases 0.000 description 6
- 230000001276 controlling effect Effects 0.000 description 6
- 230000007423 decrease Effects 0.000 description 6
- 230000003134 recirculating effect Effects 0.000 description 6
- 230000004936 stimulating effect Effects 0.000 description 6
- 230000001684 chronic effect Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 229920001971 elastomer Polymers 0.000 description 5
- 239000000806 elastomer Substances 0.000 description 5
- 239000000945 filler Substances 0.000 description 5
- 239000006260 foam Substances 0.000 description 5
- 230000001537 neural effect Effects 0.000 description 5
- 230000002829 reductive effect Effects 0.000 description 5
- 230000035807 sensation Effects 0.000 description 5
- 208000005298 acute pain Diseases 0.000 description 4
- 239000004964 aerogel Substances 0.000 description 4
- 229920005601 base polymer Polymers 0.000 description 4
- 239000000560 biocompatible material Substances 0.000 description 4
- 230000005540 biological transmission Effects 0.000 description 4
- 239000004020 conductor Substances 0.000 description 4
- 239000002826 coolant Substances 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 239000000017 hydrogel Substances 0.000 description 4
- 238000001727 in vivo Methods 0.000 description 4
- 230000001965 increasing effect Effects 0.000 description 4
- 230000002427 irreversible effect Effects 0.000 description 4
- 230000002085 persistent effect Effects 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 208000017667 Chronic Disease Diseases 0.000 description 3
- 208000028389 Nerve injury Diseases 0.000 description 3
- 229920005830 Polyurethane Foam Polymers 0.000 description 3
- 230000001154 acute effect Effects 0.000 description 3
- 239000000090 biomarker Substances 0.000 description 3
- 230000008859 change Effects 0.000 description 3
- 230000000763 evoking effect Effects 0.000 description 3
- 230000028993 immune response Effects 0.000 description 3
- 210000003127 knee Anatomy 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 230000008764 nerve damage Effects 0.000 description 3
- 230000036961 partial effect Effects 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 239000011496 polyurethane foam Substances 0.000 description 3
- 229920013683 Celanese Polymers 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 2
- 239000004793 Polystyrene Substances 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 229920000249 biocompatible polymer Polymers 0.000 description 2
- 239000012876 carrier material Substances 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 238000006731 degradation reaction Methods 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 238000011065 in-situ storage Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000011859 microparticle Substances 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 239000002002 slurry Substances 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 230000002889 sympathetic effect Effects 0.000 description 2
- 210000001186 vagus nerve Anatomy 0.000 description 2
- 230000009278 visceral effect Effects 0.000 description 2
- 238000010146 3D printing Methods 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010019280 Heart failures Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101000827703 Homo sapiens Polyphosphoinositide phosphatase Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010053156 Musculoskeletal discomfort Diseases 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010068106 Occipital neuralgia Diseases 0.000 description 1
- 102100023591 Polyphosphoinositide phosphatase Human genes 0.000 description 1
- 208000004550 Postoperative Pain Diseases 0.000 description 1
- 101100012902 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) FIG2 gene Proteins 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 206010046555 Urinary retention Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 238000002679 ablation Methods 0.000 description 1
- 230000004323 axial length Effects 0.000 description 1
- 210000003050 axon Anatomy 0.000 description 1
- 238000009529 body temperature measurement Methods 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000004917 carbon fiber Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 239000011231 conductive filler Substances 0.000 description 1
- 229920001940 conductive polymer Polymers 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 239000013536 elastomeric material Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000008029 eradication Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 239000011152 fibreglass Substances 0.000 description 1
- 229910002804 graphite Inorganic materials 0.000 description 1
- 239000010439 graphite Substances 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000004217 heart function Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000012212 insulator Substances 0.000 description 1
- 230000001788 irregular Effects 0.000 description 1
- 208000024765 knee pain Diseases 0.000 description 1
- 238000013150 knee replacement Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007257 malfunction Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 210000001617 median nerve Anatomy 0.000 description 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Chemical compound C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000021317 sensory perception Effects 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000011343 solid material Substances 0.000 description 1
- 210000000278 spinal cord Anatomy 0.000 description 1
- 210000003594 spinal ganglia Anatomy 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 238000003892 spreading Methods 0.000 description 1
- 210000001590 sural nerve Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 238000000015 thermotherapy Methods 0.000 description 1
- 210000002972 tibial nerve Anatomy 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/0085—Devices for generating hot or cold treatment fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/08—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by means of electrically-heated probes
- A61B18/082—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0212—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument inserted into a body lumen, e.g. catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0237—Characteristics of handpieces or probes with a thermoelectric element in the probe for cooling purposes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
- A61B2018/0231—Characteristics of handpieces or probes
- A61B2018/0262—Characteristics of handpieces or probes using a circulating cryogenic fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
- A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
- A61F2007/0071—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a resistor, e.g. near the spot to be heated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
- A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
- A61F2007/0077—Details of power supply
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F2007/0093—Heating or cooling appliances for medical or therapeutic treatment of the human body programmed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
- A61F2007/0228—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof with belt or strap, e.g. with buckle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
- A61F2007/0246—Compresses or poultices for effecting heating or cooling with layers with a layer having high heat transfer capability
- A61F2007/0247—Using a substance with high conductivity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
- A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
- A61F2007/0253—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability using a substance with low conductivity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
- A61F2007/0285—Local anaesthetic effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/12—Devices for heating or cooling internal body cavities
- A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Electrotherapy Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862686712P | 2018-06-19 | 2018-06-19 | |
| US62/686,712 | 2018-06-19 | ||
| PCT/US2019/038065 WO2019246318A1 (en) | 2018-06-19 | 2019-06-19 | Systems and methods for thermal blockade of nerves |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN112566572A CN112566572A (zh) | 2021-03-26 |
| CN112566572B true CN112566572B (zh) | 2024-10-01 |
Family
ID=68983075
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201980054662.8A Active CN112566572B (zh) | 2018-06-19 | 2019-06-19 | 用于神经的热阻断的系统和方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP3810003A4 (ja) |
| JP (1) | JP7513528B2 (ja) |
| CN (1) | CN112566572B (ja) |
| AU (2) | AU2019288384B2 (ja) |
| CA (1) | CA3104484A1 (ja) |
| WO (1) | WO2019246318A1 (ja) |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK68566C (da) | 1945-12-17 | 1949-02-14 | Etienne Patrizi | Transmissionsrem. |
| DK94905C (da) | 1957-06-05 | 1962-12-03 | American Marietta Co | Fremgangsmåde til fremstilling af et pulverformet blodprodukt, som kan forarbejdes til lim. |
| DK102427C (da) | 1961-06-08 | 1965-08-23 | Ernst Koller | Dørkonstruktion. |
| PT73364B (en) | 1980-07-15 | 1982-08-19 | Israel Melcer | Sole of rigid material specially wood and shoes and boots equipped therewith |
| US4585002A (en) * | 1985-04-22 | 1986-04-29 | Igor Kissin | Method and apparatus for treatment of pain by frequently alternating temperature stimulation |
| DE60023118T2 (de) * | 1999-01-04 | 2006-07-13 | Medivance, Inc., Louisville | Verbessertes kühl-/heizkissen und -system |
| US7162303B2 (en) * | 2002-04-08 | 2007-01-09 | Ardian, Inc. | Renal nerve stimulation method and apparatus for treatment of patients |
| AU2003241673A1 (en) * | 2002-06-17 | 2003-12-31 | Atsuo Mori | Catheter for topical cooling and topical cooling device using the same |
| US8352026B2 (en) * | 2007-10-03 | 2013-01-08 | Ethicon, Inc. | Implantable pulse generators and methods for selective nerve stimulation |
| US8233976B2 (en) * | 2007-12-05 | 2012-07-31 | The Invention Science Fund I, Llc | System for transdermal chemical modulation of neural activity |
| US8180446B2 (en) * | 2007-12-05 | 2012-05-15 | The Invention Science Fund I, Llc | Method and system for cyclical neural modulation based on activity state |
| KR102067583B1 (ko) * | 2011-12-09 | 2020-01-17 | 메타벤션, 인크. | 간 시스템의 치료적 신경조절 |
| US9579247B2 (en) * | 2011-12-16 | 2017-02-28 | Chordate Medical Ab | Treatment of headache disorders |
| US20140081659A1 (en) * | 2012-09-17 | 2014-03-20 | Depuy Orthopaedics, Inc. | Systems and methods for surgical and interventional planning, support, post-operative follow-up, and functional recovery tracking |
| AU2013344545A1 (en) * | 2012-11-15 | 2015-05-07 | Ebb Therapeutics, Inc. | Non-invasive brain temperature regulating devices for enhancing sleep |
| US8880167B2 (en) * | 2013-02-13 | 2014-11-04 | Flint Hills Scientific, Llc | Selective recruitment and activation of fiber types in nerves for the control of undesirable brain state changes |
| US9295512B2 (en) * | 2013-03-15 | 2016-03-29 | Myoscience, Inc. | Methods and devices for pain management |
| US20150366703A1 (en) * | 2014-06-18 | 2015-12-24 | Xing Du | Alternating hot and cold therapy apparatus |
| US20160022478A1 (en) * | 2014-07-25 | 2016-01-28 | Cascade Wellness Technologies, Inc. | Thermal contrast therapy systems, devices and methods |
| EP3190924B1 (en) * | 2014-09-10 | 2020-02-26 | Board of Regents, The University of Texas System | A controlled climate bed with sleeper feedback |
| CN107073263B (zh) * | 2014-09-12 | 2021-07-23 | 纽若斯医疗公司 | 用于大型人类神经干中的神经调控的神经封套电极 |
| US10105540B2 (en) * | 2015-11-09 | 2018-10-23 | Bluewind Medical Ltd. | Optimization of application of current |
| US11051975B2 (en) * | 2015-12-03 | 2021-07-06 | University of Pittsburgh—of the Commonwealth System of Higher Education | Device and method for nerve block by local cooling to room temperature |
| US9849059B2 (en) * | 2016-01-21 | 2017-12-26 | Andrew Shoup | Headache mitigating apparatus |
-
2019
- 2019-06-19 CN CN201980054662.8A patent/CN112566572B/zh active Active
- 2019-06-19 JP JP2020570509A patent/JP7513528B2/ja active Active
- 2019-06-19 CA CA3104484A patent/CA3104484A1/en active Pending
- 2019-06-19 WO PCT/US2019/038065 patent/WO2019246318A1/en unknown
- 2019-06-19 AU AU2019288384A patent/AU2019288384B2/en active Active
- 2019-06-19 EP EP19822441.2A patent/EP3810003A4/en active Pending
-
2024
- 2024-09-18 AU AU2024219821A patent/AU2024219821A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3810003A1 (en) | 2021-04-28 |
| CA3104484A1 (en) | 2019-12-26 |
| JP7513528B2 (ja) | 2024-07-09 |
| AU2019288384A1 (en) | 2021-02-04 |
| AU2024219821A1 (en) | 2024-10-31 |
| AU2019288384B2 (en) | 2024-06-20 |
| EP3810003A4 (en) | 2022-07-20 |
| CN112566572A (zh) | 2021-03-26 |
| WO2019246318A1 (en) | 2019-12-26 |
| JP2021528151A (ja) | 2021-10-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20240041512A1 (en) | Devices for thermally-induced renal neuromodulation | |
| JP5650137B2 (ja) | エネルギー誘導域を用いた電動筋肉刺激システム及び方法 | |
| CA2312071C (en) | Modulated high frequency tissue modification | |
| EP0132276B1 (en) | Implantable hyperthermia device and system | |
| US9295517B2 (en) | System and method for generating heat at target area of patient's body | |
| US20250205079A1 (en) | Apparatus and method for thermal blockade of nerves | |
| JP6953407B2 (ja) | 室温への局部冷却による神経ブロックのための装置および方法 | |
| JP2019534752A (ja) | 求心性神経線維を選択的に活性化する為の装置及び方法 | |
| US10232188B2 (en) | Single cable apparatus and method for hyperthermic treatments | |
| CN112566572B (zh) | 用于神经的热阻断的系统和方法 | |
| EP4076632B1 (en) | Apparatus for thermal blockade of nerves | |
| US20230172542A1 (en) | System, Method and Apparatus for Control of Shivering During Targeted Temperature Management |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |