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CN112535481B - A method and device for measuring joint contact force based on near-infrared light - Google Patents

A method and device for measuring joint contact force based on near-infrared light Download PDF

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CN112535481B
CN112535481B CN202011324643.3A CN202011324643A CN112535481B CN 112535481 B CN112535481 B CN 112535481B CN 202011324643 A CN202011324643 A CN 202011324643A CN 112535481 B CN112535481 B CN 112535481B
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陈文斌
范翔
熊蔡华
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Huazhong University of Science and Technology
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    • AHUMAN NECESSITIES
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Abstract

The invention belongs to the field of human body measurement, and particularly discloses a joint contact force measuring method and device based on near infrared light. The measuring method specifically comprises the following steps: near infrared light is emitted to the joint to be detected, reflected light is generated after the near infrared light interacts with cartilage tissues, and the change of the joint contact force is detected through the light intensity change of the reflected light. The method utilizes the characteristic that near infrared light has penetrability in biological tissues to interact with cartilage tissues and generate reflected light, realizes real-time monitoring on the joint contact force by measuring the intensity of the radiated light in real time, can avoid harm to a human body compared with a direct measurement method of implanting a prosthesis, and has the advantages of good real-time performance, small calculated amount and simple processing process. Meanwhile, the device can measure the contact force inside the joint under the condition that a wearer bears a load only by simple wearing and calibration.

Description

一种基于近红外光的关节接触力测量方法及装置A method and device for measuring joint contact force based on near-infrared light

技术领域technical field

本发明属于人体测量领域,更具体地,涉及一种基于近红外光的关节接触力测量方法及装置。The invention belongs to the field of anthropometry, and more specifically relates to a method and device for measuring joint contact force based on near-infrared light.

背景技术Background technique

在人的日常活动中,关节在承受负载、产生力矩、传导体重时都会形成关节接触力,因此关节接触力的信息在关节疾病的诊断与生物力学分析等方面具有重要的参考意义。In people's daily activities, joints will form joint contact force when bearing load, generating torque, and transmitting body weight. Therefore, the information of joint contact force has important reference significance in the diagnosis of joint diseases and biomechanical analysis.

在关节接触力的测量方法的发展历史中,对关节接触力的直接测量往往是侵入式的,如将带有测力传感器单元的胫骨假体通过手术植入膝关节内,以此实现对关节接触力的实时准确检测。但这种方法的成本较高,应用场景因其侵入测量的特点而受到较大局限。In the history of the development of joint contact force measurement methods, the direct measurement of joint contact force is often invasive, such as implanting a tibial prosthesis with a load cell unit into the knee joint through surgery to achieve joint Real-time accurate detection of contact force. However, the cost of this method is high, and the application scenarios are relatively limited due to the characteristics of intrusive measurement.

而非侵入式的关节接触力测量方法包括基于动力学的方法、基于优化的方法、基于肌肉电信号的方法等,这些方法都需要较多的传感器信息作为输入,例如结合运动捕捉系统、地面接触力测量系统、肌肉电信号传感器等测量手段获得肢体的相关动力学信息,并对该类信息进行处理与分析,来间接估计关节接触力及其变化情况。这些非侵入式的测量方法严重依赖于个体精确的肌骨系统模型与肢体动力学模型,且往往需要较复杂的传感器系统,计算复杂度高,难以实现便携式的实时测量。Non-invasive joint contact force measurement methods include methods based on dynamics, methods based on optimization, methods based on muscle electrical signals, etc., all of which require more sensor information as input, such as combining motion capture systems, ground contact Force measurement systems, muscle electrical signal sensors and other measurement methods obtain relevant dynamic information of the limbs, and process and analyze such information to indirectly estimate joint contact forces and their changes. These non-invasive measurement methods rely heavily on the individual's accurate musculoskeletal system model and limb dynamics model, and often require a more complex sensor system with high computational complexity, making it difficult to achieve portable real-time measurement.

发明内容Contents of the invention

针对现有技术的以上缺陷或改进需求,本发明提供了一种基于近红外光的关节接触力测量方法及装置,其中该方法利用近红外光在生物组织内具有穿透性的特点,使其与软骨组织发生相互作用并产生反射光,通过实时测量反射光的强度实现对关节接触力的实时监测,因而尤其适用于人体测量的应用场合。In view of the above defects or improvement needs of the prior art, the present invention provides a method and device for measuring joint contact force based on near-infrared light, wherein the method utilizes the penetrating characteristics of near-infrared light in biological tissues, making it It interacts with cartilage tissue and generates reflected light, and realizes real-time monitoring of joint contact force by measuring the intensity of reflected light in real time, so it is especially suitable for anthropometric applications.

为实现上述目的,按照本发明的一个方面,提出了一种基于近红外光的关节接触力测量方法,该测量方法具体为:向待测关节发射近红外光,所述近红外光与软骨组织发生相互作用后产生反射光,通过所述反射光的光强变化检测关节接触力的变化。In order to achieve the above object, according to one aspect of the present invention, a method for measuring joint contact force based on near-infrared light is proposed. After the interaction occurs, reflected light is generated, and the change of joint contact force is detected through the change of light intensity of the reflected light.

作为进一步优选地,所述近红外的波长为850nm~1000nm。As a further preference, the near-infrared wavelength is 850nm-1000nm.

作为进一步优选地,利用激光二极管或发光二极管发射所述近红外光。As a further preference, a laser diode or a light emitting diode is used to emit the near-infrared light.

作为进一步优选地,利用雪崩光电二极管、光电二极管或光电倍增管检测所述反射光的光强变化。As a further preference, an avalanche photodiode, a photodiode or a photomultiplier tube is used to detect the light intensity change of the reflected light.

按照本发明的另一方面,提出了一种基于近红外光的关节接触力测量装置,该测量装置包括穿戴单元、光源单元和光敏单元,其中:According to another aspect of the present invention, a kind of joint contact force measuring device based on near-infrared light is proposed, and the measuring device includes a wearing unit, a light source unit and a photosensitive unit, wherein:

所述穿戴单元用于将所述测量装置固定在待测关节的外侧;The wearing unit is used to fix the measuring device on the outside of the joint to be measured;

所述光源单元固定在所述穿戴单元上,用于向所述待测关节发射近红外光,所述近红外光与软骨组织发生相互作用并产生反射光;The light source unit is fixed on the wearing unit, and is used for emitting near-infrared light to the joint to be tested, and the near-infrared light interacts with cartilage tissue and generates reflected light;

所述光敏单元固定在所述穿戴单元上,并位于所述光源单元的一侧,用于检测所述反射光的光强变化,以此完成关节接触力测量。The photosensitive unit is fixed on the wearing unit and located on one side of the light source unit, and is used to detect the light intensity change of the reflected light, so as to complete the joint contact force measurement.

作为进一步优选地,所述光源单元采用激光二极管或发光二极管。As a further preference, the light source unit adopts a laser diode or a light emitting diode.

作为进一步优选地,所述光敏单元采用雪崩光电二极管、光电二极管或光电倍增管。As a further preference, the photosensitive unit adopts an avalanche photodiode, a photodiode or a photomultiplier tube.

作为进一步优选地,所述光源单元与光敏单元之间的距离大于8mm。As a further preference, the distance between the light source unit and the photosensitive unit is greater than 8mm.

总体而言,通过本发明所构思的以上技术方案与现有技术相比,主要具备以下的技术优点:Generally speaking, compared with the prior art, the above technical solution conceived by the present invention mainly has the following technical advantages:

1.本发明提供了一种基于近红外光的关节接触力测量方法,该方法利用近红外光在生物组织内具有穿透性的特点,使其与软骨组织发生相互作用并产生反射光,通过实时测量放射光的强度实现对关节接触力的实时监测,相比于植入假体的直接测量方法,能够避免对人体产生伤害,具有实时性好、计算量小、处理过程简单的优势;1. The present invention provides a method for measuring joint contact force based on near-infrared light. This method utilizes the penetrating characteristics of near-infrared light in biological tissues to make it interact with cartilage tissue and generate reflected light. Real-time measurement of the intensity of radiated light realizes real-time monitoring of joint contact force. Compared with the direct measurement method of implanting prostheses, it can avoid harm to the human body, and has the advantages of good real-time performance, small calculation amount, and simple processing process;

2.尤其是,本发明通过对近红外光的波长进行优化,能够使其在生物组织内穿透较深,有效提高关节接触力的检测精度;2. In particular, by optimizing the wavelength of near-infrared light in the present invention, it can penetrate deeply into biological tissues and effectively improve the detection accuracy of joint contact force;

3.此外,本发明还提供了一种基于近红外光的关节接触力测量装置,该装置只需要简单的穿戴与标定,即可实现对穿戴者负重情况下关节内部接触力的测量;不同于传统的优化迭代估计、利用表面肌电间接估计等非入侵式装置需要大量传感器的缺陷,本发明只需要一对光敏单元与光源单元即可进行关节接触力的测量,极大地降低了传感器的数量,简化了数据分析处理的复杂程度。3. In addition, the present invention also provides a joint contact force measurement device based on near-infrared light. The device only needs simple wearing and calibration to measure the internal contact force of the joint under the load-bearing condition of the wearer; different from Traditional non-invasive devices such as optimized iterative estimation and indirect estimation using surface electromyography require a large number of sensors. The present invention only needs a pair of photosensitive units and light source units to measure joint contact force, which greatly reduces the number of sensors. , which simplifies the complexity of data analysis and processing.

附图说明Description of drawings

图1是本发明提供的基于近红外光的关节接触力测量方法的原理图;Fig. 1 is the schematic diagram of the joint contact force measurement method based on near-infrared light provided by the present invention;

图2是本发明优选实施例中膝关节受力时的测量示意图,其中(a)为膝关节受力示意图,(b)测量示意图;Fig. 2 is a schematic diagram of measurement when the knee joint is stressed in a preferred embodiment of the present invention, wherein (a) is a schematic diagram of knee joint stress, and (b) is a schematic measurement diagram;

图3是按照本发明优选实施例构建的基于近红外光的关节接触力测量装置的结构示意图;Fig. 3 is a structural schematic diagram of a joint contact force measurement device based on near-infrared light constructed according to a preferred embodiment of the present invention;

图4是本发明优选实施例中固定件的结构示意图,其中(a)为主视图,(b)为剖视图;Fig. 4 is a schematic structural view of a fixture in a preferred embodiment of the present invention, wherein (a) is a front view, and (b) is a cross-sectional view;

图5是本发明优选实施例中使用的发光二极管的驱动与调制部分电路示意图;Fig. 5 is a schematic diagram of the drive and modulation part of the LED used in the preferred embodiment of the present invention;

图6是本发明优选实施例中使用的雪崩光电二极管的驱动与采集部分电路示意图;6 is a schematic diagram of the drive and acquisition part of the avalanche photodiode used in the preferred embodiment of the present invention;

图7是本发明优选实施例中膝关节软骨变形与反射光光强变化图;Fig. 7 is a graph showing the deformation of knee articular cartilage and the variation of reflected light intensity in a preferred embodiment of the present invention;

图8是本发明优选实施例中待测关节压力变化引起的反射光光强信号变化数据图。Fig. 8 is a data diagram of changes in reflected light intensity signals caused by changes in joint pressure to be measured in a preferred embodiment of the present invention.

在所有附图中,相同的附图标记用来表示相同的元件或结构,其中:Throughout the drawings, the same reference numerals are used to designate the same elements or structures, wherein:

1-穿戴单元,2-光敏单元,3-光源单元,4-固定件。1-wearing unit, 2-photosensitive unit, 3-light source unit, 4-fixing piece.

具体实施方式Detailed ways

为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅仅用以解释本发明,并不用于限定本发明。此外,下面所描述的本发明各个实施方式中所涉及到的技术特征只要彼此之间未构成冲突就可以相互组合。In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention. In addition, the technical features involved in the various embodiments of the present invention described below can be combined with each other as long as they do not constitute a conflict with each other.

如图1、2所示,本发明实施例提供了一种基于近红外光的关节接触力测量方法,该测量方法具体为:向待测关节发射近红外光,近红外光与软骨组织发生相互作用后产生反射光,通过反射光的光强变化检测关节接触力的变化。As shown in Figures 1 and 2, the embodiment of the present invention provides a method for measuring joint contact force based on near-infrared light. Reflected light is generated after the action, and the change of joint contact force is detected through the change of the light intensity of the reflected light.

具体地,当人站立以及负重时,膝关节会承受由体重产生的压力,这种压力会以关节接触力的形式由股骨和胫骨上的关节软骨传递,当人运动时,膝关节又需要产生关节力矩,在肌肉力的作用下,也会在关节软骨上产生接触力。这样的关节接触力就是作用在关节软骨上的压力,关节软骨在这样的压缩应力作用下,便会发生相应程度的变形,于是通过测量关节软骨变形程度,就可以实现对关节接触力的实时检测。Specifically, when a person stands and bears weight, the knee joint will bear the pressure generated by the body weight. This pressure will be transmitted by the articular cartilage on the femur and tibia in the form of joint contact force. When the person moves, the knee joint needs to generate Joint moments, under the action of muscle forces, also generate contact forces on the articular cartilage. Such joint contact force is the pressure acting on the articular cartilage. Under such compressive stress, the articular cartilage will be deformed to a certain degree. Therefore, by measuring the deformation degree of the articular cartilage, real-time detection of the joint contact force can be realized. .

近红外光(波长为780nm~1000nm)在生物质组织内可穿透较深,通过测量近红外光在生物组织内吸收、散射等相互作用后出射的反射光强度,可以监测生物组织的变化情况。因此,当关节软骨由于关节接触力变化而产生变形时,近红外光吸收、散射强度也将发生变化,通过待测关节处反射光强度的变化可以实现关节接触力的测量。由于不同区域光强信号的差异性,可以通过标定的方式或多路信号分析的方式进行处理,以实现对关节接触力的准确测量。Near-infrared light (with a wavelength of 780nm to 1000nm) can penetrate deeply in biological tissue. By measuring the intensity of reflected light emitted after the interaction of near-infrared light in biological tissue, such as absorption and scattering, the changes in biological tissue can be monitored. . Therefore, when the articular cartilage deforms due to changes in the joint contact force, the near-infrared light absorption and scattering intensity will also change, and the measurement of the joint contact force can be realized through the change in the reflected light intensity at the joint to be measured. Due to the difference of light intensity signals in different areas, it can be processed by calibration or multi-channel signal analysis to achieve accurate measurement of joint contact force.

进一步,近红外的波长为850nm~1000nm,该波长范围内的近红外光穿透性较好,近红外的波长优选为850nm左右或950nm左右;利用激光二极管或发光二极管发射近红外光;利用雪崩光电二极管、光电二极管或光电倍增管检测反射光的光强变化。Further, the near-infrared wavelength is 850nm-1000nm, and the near-infrared light penetration in this wavelength range is better, and the near-infrared wavelength is preferably about 850nm or about 950nm; use laser diodes or light-emitting diodes to emit near-infrared light; use avalanche Photodiodes, photodiodes, or photomultiplier tubes detect changes in the intensity of reflected light.

如图3、4所示,按照本发明的另一方面,提供了一种基于近红外光的关节接触力测量装置,该测量装置包括穿戴单元1、光源单元3和光敏单元2,其中:As shown in Figures 3 and 4, according to another aspect of the present invention, a joint contact force measurement device based on near-infrared light is provided, the measurement device includes a wearable unit 1, a light source unit 3 and a photosensitive unit 2, wherein:

穿戴单元1用于将测量装置固定在待测关节的外侧,使其贴近待测关节处,穿戴单元1优选采用绑带结构;The wearing unit 1 is used to fix the measuring device on the outside of the joint to be measured so that it is close to the joint to be measured, and the wearing unit 1 preferably adopts a strap structure;

光源单元3通过固定件4固定在穿戴单元上,用于向待测关节发射一定强度的近红外光,近红外光与软骨组织发生相互作用并产生反射光;The light source unit 3 is fixed on the wearing unit through the fixing part 4, and is used for emitting near-infrared light of a certain intensity to the joint to be tested, and the near-infrared light interacts with the cartilage tissue and generates reflected light;

光敏单元2通过固定件4固定在穿戴单元上,并位于光源单元的一侧,与光源单元3通过导线连接,用于检测反射光的光强变化,以此完成关节接触力测量。The photosensitive unit 2 is fixed on the wearing unit through the fixing piece 4, and is located on one side of the light source unit, and is connected with the light source unit 3 by a wire to detect the light intensity change of the reflected light, thereby completing the joint contact force measurement.

可以采用一个发光元件与一个光敏元件,平行于软骨方向进行布置,或垂直于软骨方向进行布置;也可以采用多个发光元件与多个光敏元件,分布于待测关节外围,从而实现多路信号采集,同时分析多个特定区域软骨组织对不同近红外波长的探测光强变化,以实现更精确的关节接触力测量。One light-emitting element and one photosensitive element can be used to arrange parallel to or perpendicular to the direction of cartilage; multiple light-emitting elements and multiple photosensitive elements can also be used to distribute around the joint to be tested, so as to realize multi-channel signal Acquisition and simultaneous analysis of changes in the detection light intensity of cartilage tissue in multiple specific regions for different near-infrared wavelengths to achieve more accurate measurement of joint contact force.

在使用前,通过对待测关节所受的外部载荷以及受载前后反射光光强的变化量进行离线标定,建立关节接触力与反射光光强之间的对应关系,然后在使用时就可以根据采集到的光强信号估计关节接触力,从而实现对关节接触力的实时测量。通过实时测量待测关节组织与近红外光相互作用后出射的光强信号并输入到经过标定的数据处理模块中,即可完成对待测关节接触力的实时分析与处理,实时性好,计算量小,穿戴结构简单,不需要复杂的分析处理过程,适合于关节接触力的实时测量。Before use, through the offline calibration of the external load on the joint to be tested and the change of the reflected light intensity before and after loading, the corresponding relationship between the joint contact force and the reflected light intensity can be established, and then it can be used according to the The collected light intensity signals estimate the joint contact force, so as to realize the real-time measurement of the joint contact force. Real-time analysis and processing of the contact force of the joint to be tested can be completed by measuring the light intensity signal emitted after the interaction between the joint tissue to be tested and the near-infrared light in real time and inputting it into the calibrated data processing module. It is small, has a simple wearable structure, does not require complex analysis and processing, and is suitable for real-time measurement of joint contact force.

进一步,光源单元3采用激光二极管或发光二极管,其中发光二极管(LED)的驱动与调制部分电路如图5所示,通过电池供电驱动,并通过STM32单片机调制驱动,从而实现对LED输出光强的调制;光敏单元2采用雪崩光电二极管、光电二极管或光电倍增管,其中雪崩光电二极管(APD)的驱动与调制部分电路如图6所示,通过电池驱动放大电路,通过AD转换模块采集电压信号,传输至PC机进行处理分析;光源单元3与光敏单元2之间的距离大于8mm。Further, the light source unit 3 adopts a laser diode or a light-emitting diode, wherein the driving and modulating part of the circuit of the light-emitting diode (LED) is shown in Figure 5, which is driven by battery power and modulated by the STM32 single-chip microcomputer, so as to realize the control of the output light intensity of the LED. Modulation; the photosensitive unit 2 adopts an avalanche photodiode, a photodiode or a photomultiplier tube, wherein the drive and modulation part of the avalanche photodiode (APD) circuit is shown in Figure 6, the amplifying circuit is driven by a battery, and the voltage signal is collected by an AD conversion module. It is transmitted to a PC for processing and analysis; the distance between the light source unit 3 and the photosensitive unit 2 is greater than 8mm.

在本发明的优选实施例中,选用波长为850nm的LED、滨松-C12702型APD模块,搭建如图5、6所示的驱动、调制与采集电路,APD采集的漫反射信号通过光纤从待测膝关节处引出至APD感光区域,穿戴部分光源与光敏测量区域中心距离固定为10mm,测量膝关节受力变化并发生软骨变形时的漫反射光强(即漫反射探测区域出射光子数)。In a preferred embodiment of the present invention, the LED and Hamamatsu-C12702 type APD modules with a wavelength of 850nm are used to build the drive, modulation and acquisition circuits shown in Figures 5 and 6, and the diffuse reflection signal collected by the APD passes through the optical fiber from the The distance from the knee joint to the photosensitive area of the APD is fixed at 10mm between the wearing part of the light source and the center of the photosensitive measurement area, and the diffuse reflection light intensity (that is, the number of photons emitted from the diffuse reflection detection area) is measured when the knee joint is subjected to changes in force and cartilage deformation occurs.

结合蒙特卡洛方法进行分析,得到图7所示的数据图,可以看到,在关节软骨受压导致厚度变化时,漫反射光强会随着关节软骨的压缩而变强。Combining the analysis with the Monte Carlo method, the data graph shown in Figure 7 is obtained. It can be seen that when the articular cartilage is compressed and the thickness changes, the diffuse reflection light intensity will become stronger with the compression of the articular cartilage.

穿戴者穿戴装置进行实验数据采集,得到图8所示的数据图,在膝关节受压力变化时,漫反射光强的变化趋势呈现出与蒙特卡洛方法分析结果相同的趋势,当关节受压力较大时,漫反射光强会变强,在实验中,可以根据这种数据特性分析关节接触力的变化情况。以此实现关节接触力的实时检测。The wearer wears the device for experimental data collection, and the data graph shown in Figure 8 is obtained. When the pressure on the knee joint changes, the change trend of the diffuse reflection light intensity presents the same trend as the analysis result of the Monte Carlo method. When the joint is under pressure When the value is larger, the diffuse light intensity will become stronger. In the experiment, the change of joint contact force can be analyzed according to this data characteristic. In this way, real-time detection of joint contact force is realized.

本领域的技术人员容易理解,以上所述仅为本发明的较佳实施例而已,并不用以限制本发明,凡在本发明的精神和原则之内所作的任何修改、等同替换和改进等,均应包含在本发明的保护范围之内。It is easy for those skilled in the art to understand that the above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention, All should be included within the protection scope of the present invention.

Claims (7)

1. A joint contact force measuring method based on near infrared light is characterized by comprising the following steps: emitting near infrared light to a joint to be detected, generating reflected light after the near infrared light interacts with cartilage tissues, and detecting the change of the joint contact force through the light intensity change of the reflected light, wherein the wavelength of the near infrared light is 850 nm-1000 nm.
2. The near-infrared-based contact force measuring method of claim 1, wherein the near-infrared light is emitted using a laser diode or a light emitting diode.
3. The near-infrared-based contact force measuring method for joints according to claim 1 or 2, wherein the change in light intensity of the reflected light is detected by an avalanche photodiode or a photomultiplier tube.
4. The utility model provides a joint contact force measuring device based on near infrared light, its characterized in that, this measuring device is including wearing unit, light source unit and photosensitive unit, wherein:
the wearing unit is used for fixing the measuring device on the outer side of the joint to be measured;
the light source unit is fixed on the wearing unit and used for emitting near infrared light to the joint to be detected, and the near infrared light interacts with cartilage tissues and generates reflected light;
the photosensitive unit is fixed on the wearing unit, is positioned on one side of the light source unit and is used for detecting the light intensity change of the reflected light so as to complete the measurement of the joint contact force.
5. The near-infrared-based articular contact force measurement device according to claim 4, wherein the light source unit employs a laser diode or a light emitting diode.
6. The near-infrared-based articular contact force measurement device of claim 4, wherein the photosensitive cells employ avalanche photodiodes or photomultiplier tubes.
7. The near-infrared-light-based articular contact force measurement device according to any one of claims 4 to 6, wherein the distance between the light source unit and the light-sensitive unit is greater than 8mm.
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