CN112529980B - A Multi-target Finite-Angle CT Image Reconstruction Method Based on Minimization - Google Patents
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Abstract
本发明涉及一种基于极大极小化的多目标有限角CT图像重建方法,属于图像重建领域。该方法包括以下步骤:S1:采集投影数据:S2:建立多目标有限角CT图像重建模型;S3:有限角CT迭代重建;S4:输出重建图像。利用非下采样轮廓波变换的多尺度、多分辨率分解和伪影方向性特点,设立非下采样轮廓波变换的L0范数最小化和图像梯度的L0范数2个优化目标,建立了多目标优化重建模型。采用该方法,能够有效地抑制重建图像的伪影和噪声并保护图像边界,从而提高CT重建图像的质量。
The invention relates to a multi-target limited-angle CT image reconstruction method based on minimization, and belongs to the field of image reconstruction. The method includes the following steps: S1: collecting projection data; S2: establishing a multi-target finite-angle CT image reconstruction model; S3: finite-angle CT iterative reconstruction; S4: outputting a reconstructed image. Taking advantage of the multi-scale, multi-resolution decomposition and artifact directional characteristics of non-subsampling contourlet transform, two optimization objectives, namely, the minimization of the L0 norm of the non-subsampled contourlet transform and the L0 norm of the image gradient, are established. Objective-optimized reconstruction of the model. By adopting this method, the artifacts and noise of the reconstructed image can be effectively suppressed and the image boundary can be protected, thereby improving the quality of the CT reconstructed image.
Description
技术领域technical field
本发明属于图像重建领域,涉及一种基于极大极小化的多目标有限角CT图像重建方法。The invention belongs to the field of image reconstruction, and relates to a maximin-based multi-target limited-angle CT image reconstruction method.
背景技术Background technique
在有些特定的应用或扫描场景下,例如:C型臂CT(ComputedTomography)、长尺寸物体在役检测等,只能够在一定的角度范围内采集投影数据,该扫描方式的重建问题称为有限角CT重建问题。由于采集的数据不满足精确重建的条件,传统的滤波反投影重建算法将导致许多伪影出现在重建图像中,致使有些重要结构信息丢失或被掩盖,很大程度地影响无损检测的精度或医生的诊断。因此如何重建出符合医生诊断要求或无损检测标准的高质量图像具有较大的实际意义。传统的代数重建算法使得重建的图像出现大量的伪影和失真现象。基于TV(TotalVariation)的图像重建算法能够有效处理稀疏角CT重建问题,但是应用到较小的有限角的扫描时,同样重建图像也会出现一定的伪影和失真。为了抑制伪影和保护边界,余维引进图像梯度L0正则化,该方法一定程度上能够抑制伪影,进一步提高重建图像的质量。王成祥等人利用小波变换的多尺度、多分辨率特点,将图像小波变换的L0拟范数作为正则化来处理有限角CT重建问题,该方法能够一定程度地提高重建图像的质量。In some specific applications or scanning scenarios, such as: C-arm CT (Computed Tomography), in-service detection of long-sized objects, etc., projection data can only be collected within a certain range of angles. The reconstruction problem of this scanning method is called limited angle. CT reconstruction problem. Since the collected data does not meet the conditions for accurate reconstruction, the traditional filtered back-projection reconstruction algorithm will cause many artifacts to appear in the reconstructed image, resulting in the loss or concealment of some important structural information, which greatly affects the accuracy of nondestructive testing or doctors. diagnosis. Therefore, how to reconstruct a high-quality image that meets the doctor's diagnostic requirements or non-destructive testing standards has great practical significance. The traditional algebraic reconstruction algorithm causes a lot of artifacts and distortions in the reconstructed image. The image reconstruction algorithm based on TV (TotalVariation) can effectively deal with the sparse-angle CT reconstruction problem, but when it is applied to a small limited-angle scan, the reconstructed image will also have certain artifacts and distortion. In order to suppress artifacts and protect boundaries, Yu Wei introduced image gradient L0 regularization, which can suppress artifacts to a certain extent and further improve the quality of reconstructed images. Wang Chengxiang and others used the multi-scale and multi-resolution characteristics of wavelet transform, and used the L0 quasi-norm of image wavelet transform as regularization to deal with limited-angle CT reconstruction problems. This method can improve the quality of reconstructed images to a certain extent.
公开号为CN 107978005A专利申请公开“一种基于保边界扩散和平滑的有限角CT图像重建算法”。该方法主要对重建图像x,y方向分别进行梯度L0保边界扩散修正来进一步提高重建图像的质量,上述专利申请所述方法能够保护边界和消除线状伪影。但是仍然存在如下的缺陷:(1)上述专利申请所述方法仅考虑图像x,y轴进行梯度L0保边界扩散修正,经过数据保真约束后进行图像x,y轴梯度L0正则化约束,为了抑制伪影可能导致图像过光滑,导致在对应缺少扫描角度的图像细节丢失;(2)上述专利申请所述方法的图像的梯度变换只有图像的高频部分高频信息,缺少对低频部分的正则化约束,也没有考虑到伪影的多方向性特征;(3)从优化的角度来说,上述专利申请所述方法是一个单目标优化方法,没有从多目标优化的角度去考虑优化多个指标。The publication number is CN 107978005A Patent Application Disclosure "A Limited Angle CT Image Reconstruction Algorithm Based on Boundary Preserving Diffusion and Smoothing". This method mainly performs gradient L0 boundary-preserving diffusion correction on the x and y directions of the reconstructed image to further improve the quality of the reconstructed image. The method described in the above patent application can protect the boundary and eliminate linear artifacts. However, the following defects still exist: (1) The method described in the above-mentioned patent application only considers the image x and y axes to perform gradient L0 boundary-preserving diffusion correction, and performs image x and y-axis gradient L0 regularization constraints after data fidelity constraints, in order to Suppressing artifacts may cause the image to be too smooth, resulting in the loss of image details corresponding to the lack of scanning angle; (2) the gradient transformation of the image in the method described in the above patent application only has high-frequency information in the high-frequency part of the image, and lacks regularization for the low-frequency part (3) From the perspective of optimization, the method described in the above-mentioned patent application is a single-objective optimization method, and does not consider optimizing multiple index.
公开号为CN 110717959A专利申请公开“基于曲率约束的x射线有限角CT图像重建方法和装置”。该方法主要对先重建出的图像进行图像梯度L0正则化稀疏约束,然后对稀疏约束的结果进行曲率约束。虽然上述专利申请所述方法考虑了2个优化指标,能够进一步克服现有的有限角CT重建算法中边界模糊或存在阶梯效应问题。但是仍然存在如下的缺陷:(1)上述专利申请所述方法的图像的梯度变换和曲率约束只有图像的高频部分高频信息,缺少对低频部分的正则化约束,也没有考虑到伪影的多方向性特征;(2)从优化的角度来说,上述专利申请所述方法虽然考虑2个优化指标(图像梯度L0约束和曲率约束),但是用单目标优化方法分别来处理这2个优化指标,没有直接从多目标优化的角度去考虑优化这2个指标;(3)这种单目标方法可能由于图像梯度L0约束导致图像过光滑,在对应缺少扫描角度的图像细节丢失,以致后面的曲率约束指标无法恢复丢失的细节。The publication number is CN 110717959A Patent Application Disclosure "X-ray Limited Angle CT Image Reconstruction Method and Device Based on Curvature Constraint". This method mainly performs image gradient L0 regularization sparse constraints on the first reconstructed image, and then performs curvature constraints on the results of the sparse constraints. Although the method described in the above-mentioned patent application considers two optimization indexes, it can further overcome the blurred boundary or the step effect in the existing limited-angle CT reconstruction algorithm. However, there are still the following defects: (1) The gradient transformation and curvature constraints of the image in the method described in the above patent application only have the high-frequency information of the high-frequency part of the image, lack of regularization constraints on the low-frequency part, and do not take into account the artifacts. Multi-directional features; (2) From an optimization point of view, although the method described in the above patent application considers two optimization indicators (image gradient L0 constraint and curvature constraint), the single-objective optimization method is used to process these two optimizations respectively indicators, and did not directly consider optimizing these two indicators from the perspective of multi-objective optimization; (3) this single-objective method may cause the image to be too smooth due to the image gradient L0 constraint, and the image details corresponding to the lack of scanning angle are lost, so that the following Curvature-constrained metrics cannot recover lost details.
公开号为CN 109697691A专利申请公开“基一种基于L0范数和奇异值阈值分解的双正则项优化的有限角投影重建方法”。该方法首主要先对重建的图像进行图像梯度L0正则化稀疏约束,然后对图像进行核范数约束。虽然上述专利申请所述方法能够恢复CT图像轮廓,减少有限角伪影。但是仍然存在如下的缺陷:(1)上述专利申请所述方法的图像的梯度变换和曲率约束只有图像的高频部分高频信息,缺少对低频部分的正则化约束,也没有考虑到伪影的多方向性特征;(2)从优化的角度来说,该方法是一个双正则化单目标优化方法,没有直接从多目标优化的角度去考虑优化图像梯度L0约束和图像核范数这2个指标。(3)这种单目标方法可能由于图像梯度L0约束导致图像过光滑,在对应缺少扫描角度的图像细节丢失,以致后面的图像核范数指标无法恢复丢失的细节。The publication number is CN 109697691A Patent Application Disclosure "Based on a Finite Angle Projection Reconstruction Method Based on Double Regular Term Optimization Based on L0 Norm and Singular Value Threshold Decomposition". In this method, the image gradient L0 regularization sparse constraint is firstly performed on the reconstructed image, and then the kernel norm constraint is performed on the image. Although the method described in the above patent application can restore the CT image contour and reduce limited angle artifacts. However, there are still the following defects: (1) The gradient transformation and curvature constraints of the image in the method described in the above patent application only have the high-frequency information of the high-frequency part of the image, lack of regularization constraints on the low-frequency part, and do not take into account the artifacts. Multi-directional features; (2) From an optimization point of view, this method is a double-regularized single-objective optimization method, and does not directly consider the optimization of image gradient L0 constraints and image kernel norms from the perspective of multi-objective optimization. index. (3) This single-target method may cause the image to be too smooth due to the constraint of the image gradient L0, and the details of the image corresponding to the lack of scanning angle are lost, so that the subsequent image kernel norm index cannot recover the lost details.
目前存在的大多数有限角CT优化重建方法没有考虑到伪影的多方向性特征,都是采用单目标优化方法去优化多个指标,也是单目标方法求解多正则化优化模型。本发明考虑图像在非下采样轮廓波变换和图像梯度变换下的稀疏性,利用非下采样轮廓波变换的多尺度、多分辨率分解和伪影方向性特点,设立非下采样轮廓波变换的L0范数最小化和图像梯度的L0范数2个优化目标,采用多目标优化中的极大极小化方法来优化这两个目标,从而提高CT重建图像的质量。Most of the existing limited-angle CT optimal reconstruction methods do not take into account the multi-directional characteristics of artifacts. They all use single-objective optimization methods to optimize multiple indicators, and single-objective methods are also used to solve multi-regularized optimization models. The invention considers the sparsity of images under non-subsampled contourlet transform and image gradient transform, utilizes the multi-scale, multi-resolution decomposition and artifact directionality characteristics of non-subsampled contourlet transform, and sets up the non-subsampled contourlet transform The minimization of the L0 norm and the L0 norm of the image gradient are two optimization objectives, and the maximinization method in the multi-objective optimization is used to optimize these two objectives, so as to improve the quality of the CT reconstruction image.
发明内容Contents of the invention
有鉴于此,本发明的目的在于提供一种基于极大极小化的多目标有限角CT图像重建方法。In view of this, the object of the present invention is to provide a multi-target limited-angle CT image reconstruction method based on maximin minimization.
为达到上述目的,本发明提供如下技术方案:To achieve the above object, the present invention provides the following technical solutions:
一种基于极大极小化的多目标有限角CT图像重建方法,该方法包括以下步骤:A method for reconstructing multi-target limited-angle CT images based on maximin and minimization, the method comprising the following steps:
S1:采集投影数据:S1: Collect projection data:
S2:建立多目标有限角CT图像重建模型;S2: Establish a multi-target limited-angle CT image reconstruction model;
S3:有限角CT迭代重建;S3: Limited-angle CT iterative reconstruction;
S4:输出重建图像。S4: Output the reconstructed image.
可选的,所述S1具体为:将射线源绕旋转中心沿着扫描轨道旋转有限的角度来获得不完备的投影数据。Optionally, the S1 specifically includes: rotating the ray source around the rotation center along the scanning orbit for a limited angle to obtain incomplete projection data.
可选的,所述S2具体为:采用离散模型进行重建时,首先需要将坐标(x,y)对应的f(x,y)按照y的维度重排成一个1维向量f,其维数为N×1,其中N=n1×n2,n1为f(x,y)在x方向的维数,n2为f(x,y)在y方向的维数;然后,将所有坐标(a,s)对应投影数据gδ(a,s)按照s的维度重排成一个1维向量gδ,列向量gδ的维数为M×1,其中M=m1×m2,m1为gδ(a,s)在a方向的维数,m2为gδ(a,s)在s方向的维数;按照本发明考虑采用非下采样轮廓波变换将重建图像分解成低频部分和高频部分,使图像进行多尺度、多分辨率分解;Optionally, the specific S2 is: when the discrete model is used for reconstruction, f(x, y) corresponding to the coordinates (x, y) first needs to be rearranged into a 1-dimensional vector f according to the dimension of y, and its dimension is N×1, where N=n 1 ×n 2 , n 1 is the dimension of f(x,y) in the x direction, n 2 is the dimension of f(x,y) in the y direction; then, all The coordinates (a, s) corresponding to the projection data g δ (a, s) are rearranged into a 1-dimensional vector g δ according to the dimension of s, and the dimension of the column vector g δ is M×1, where M=m 1 ×m 2 , m 1 is the dimension of g δ (a, s) in the a direction, m 2 is the dimension of g δ (a, s) in the s direction; according to the present invention, it is considered to use non-subsampling contourlet transform to decompose the reconstructed image into low-frequency part and high-frequency part, so that the image can be decomposed into multi-scale and multi-resolution;
为抑制噪声和伪且避免过光滑导致部分细节丢失,通过对非下采样轮廓波变换的系数进行L0稀疏正则化约束;为图像光滑,采用图像梯度的L0正则化进行约束;In order to suppress noise and artifacts and avoid loss of some details caused by over-smoothing, L0 sparse regularization constraints are performed on the coefficients of non-subsampled contourlet transformation; for image smoothness, L0 regularization of image gradients is used to constrain;
从多目标角度建立的模型如下:The model established from the multi-objective perspective is as follows:
其中A∈RM×N是有限角CT系统矩阵,f∈RN×1是待重建图像,gδ∈RM×1是有限角CT投影数据,Ω是凸集(Ω:={f|f≥0});λ是松弛参数,W是非下采样轮廓波变换,i是子带的索引;||β||0是统计β的非0元素个数,▽β=(▽xβ,▽yβ),▽xβ,▽yβ的分量形式为(▽xβ)i′,j′=βi′,j′-βi′-1,j′,(▽yβ)i′,j′=βi′,j′-βi′,j′-1;当做非下采样轮廓波变换时,将f重排成1个2维矩阵f(x,y),然后对该2维矩阵做非下采样轮廓波变换,当做完非下采样轮廓波反变换后,重新将f(x,y)按照y的维度重排成一个1维向量f。where A∈R M×N is the finite-angle CT system matrix, f∈R N×1 is the image to be reconstructed, g δ ∈ R M×1 is the finite-angle CT projection data, and Ω is a convex set (Ω:={f| f≥0}); λ is the relaxation parameter, W is the non-subsampled contourlet transform, i is the index of the subband; ||β|| 0 is the number of non-zero elements of statistics β, ▽β=(▽ x β, ▽ y β), the component form of ▽ x β,▽ y β is (▽ x β) i′,j′ =β i′,j′ -β i′-1,j′ ,(▽ y β) i′ , j′ =β i′,j′ -β i′,j′-1 ; when performing non-subsampling contourlet transformation, rearrange f into a 2-dimensional matrix f(x,y), and then The non-subsampled contourlet transformation is performed on the three-dimensional matrix. After the non-subsampled contourlet inverse transformation is completed, f(x, y) is rearranged into a 1-dimensional vector f according to the dimension of y.
可选的,所述S3具体为:Optionally, the S3 is specifically:
根据建立的模型(1),采用极大极小化方法求解模型(1);According to the established model (1), the model (1) is solved by the method of maximization and minimization;
其中步骤S3有限角CT迭代重建具体过程为:The specific process of step S3 finite-angle CT iterative reconstruction is as follows:
首先,将模型(1)通过极大极小化方法转换成单目标优化模型,其形式如下:First, the model (1) is transformed into a single-objective optimization model through the maximin method, and its form is as follows:
然后,为有效求解单目标优化模型,取λ为两个特殊的值,首先λ=1,求解对应的优化问题;然后λ=0,再求解对应的优化问题;为使得最终的解收敛,重复上述λ的取值过程;于是单目标优化模型简化如下形式:Then, in order to effectively solve the single-objective optimization model, take λ as two special values. First, λ=1 to solve the corresponding optimization problem; then λ=0, and then solve the corresponding optimization problem; in order to make the final solution converge, repeat The above value process of λ; so the single-objective optimization model is simplified as follows:
模型(3)等价如下形式:Model (3) is equivalent to the following form:
3)当λ=1时,为了求解(4)中的第一个带约束的优化模型,转换成如下形式:3) When λ=1, in order to solve the first optimization model with constraints in (4), it is converted into the following form:
其中||x||D=<Dx,x>;D是一个对角矩阵,其对角元素为且对所有i′=1,2,...,M,γi是正则化参数,再采用交替方向迭代法(ADMM)求解模型(5),其迭代格式如下:Where ||x|| D =<Dx,x>; D is a diagonal matrix, and its diagonal elements are And for all i'=1,2,...,M, γ i is the regularization parameter, and then the model (5) is solved by the alternating direction iterative method (ADMM), and the iterative format is as follows:
t是ADMM算法引入的参数;t is a parameter introduced by the ADMM algorithm;
为避免关于第一个变量f的子问题中求系统矩阵A的逆或者采用迭代法求解子问题的不足,嵌入临近交替线性化的思想,将迭代格式(6)转换为临近交替线性化的ADMM迭代格式,具体如下:In order to avoid the inverse of the system matrix A in the sub-problem about the first variable f or to use the iterative method to solve the sub-problem, the idea of adjacent alternating linearization is embedded, and the iterative format (6) is converted into ADMM of adjacent alternating linearization The iterative format, as follows:
迭代格式(7)中是临近线性化引入的松弛参数;(7)中为ART迭代更新格式;通过临近交替线性化巧妙地将经典的ART迭代算法融入其中;In iterative format (7) is the relaxation parameter introduced by the proximity linearization; in (7) Updated format for ART iteration; subtly incorporates classic ART iteration algorithm through adjacent alternating linearization;
则求出迭代格式(7)的子问题最优解,迭代格式如下所示:Then find the optimal solution to the subproblem of the iterative format (7), and the iterative format is as follows:
其中WT表示非下采样轮廓波反变换, where W T represents the non-subsampled contourlet inverse transform,
4)当λ=0时,为了求解(4)中的第二个带约束的优化模型,转换成如下形式:4) When λ=0, in order to solve the second optimization model with constraints in (4), it is converted into the following form:
其中D是一个对角矩阵,其对角元素为且对所有i′=1,2,...,M,μ是正则化参数,采用临近线性化的思想将问题转化为:where D is a diagonal matrix whose diagonal elements are And for all i'=1,2,...,M, μ is a regularization parameter, using the idea of near linearization to transform the problem into:
其中用L0最小化方法求解(10)式,其迭代格式如下:in Using the L0 minimization method to solve equation (10), the iterative format is as follows:
的迭代形式如下:对所有图像坐标i′,j′ The iterative form of is as follows: For all image coordinates i′, j′
其中表示傅里叶变换,表示傅里叶反变换,表示傅里叶变换的复共轭,▽x,▽y分别表示x,y的梯度算子;β控制相似性的参数,κ(κ>1)表示控制β增长速度的参数;n表示算法的迭代次数,算法的停机标准是β大于迭代前预设的参数βmax,当算法的停机后输出图像为fk+1;in represents the Fourier transform, represents the inverse Fourier transform, Represents the complex conjugate of Fourier transform, ▽ x , ▽ y represent the gradient operators of x and y respectively; β controls The parameter of similarity, κ (κ>1) represents the parameter that controls the growth rate of β; n represents the number of iterations of the algorithm, The stop criterion of the algorithm is that β is greater than the preset parameter β max before iteration, when The output image after the shutdown of the algorithm is f k+1 ;
设迭代格式(8)和(11)对应的停机标准为分别达到预先设定的迭代次数Nite1和Nite2,设整个算法的总迭代次数为NTot,tt为总的迭代次数索引,则迭代流程如下:Assume that the stoppage criteria corresponding to iteration formats (8) and (11) reach the preset iteration times N ite1 and N ite2 respectively , set the total number of iterations of the entire algorithm as N Tot , and tt is the index of the total number of iterations, then iteration The process is as follows:
步骤S3有限角CT迭代重建包含如下2个子步骤:Step S3 limited-angle CT iterative reconstruction includes the following two sub-steps:
S31.基于非下采样轮廓波变换的L0正则化图像重建;S31. L0 regularized image reconstruction based on non-subsampled contourlet transform;
S32.基于梯度变换的L0正则化图像重建;S32. L0 regularized image reconstruction based on gradient transformation;
其中S31包含如下3个子步骤:Wherein S31 includes the following 3 sub-steps:
S311.ART迭代重建和非下采样轮廓波反变换组合得到初步重建结果;S311. ART iterative reconstruction and non-subsampled contourlet inverse transformation are combined to obtain a preliminary reconstruction result;
S312.对得到的初步结果在非下采样轮廓波变换域对高频部分和低频部分进行硬阈值处理,来抑制伪影和噪声,与此同时进行边界保护;S313.对偶变量v更新;S312. Perform hard threshold processing on the high-frequency part and low-frequency part in the non-subsampled contourlet transform domain to the obtained preliminary results to suppress artifacts and noise, and at the same time perform boundary protection; S313. Update the dual variable v;
其中S32包含如下2个子步骤:Wherein S32 includes the following two sub-steps:
S321.ART迭代重建,其中初始图像为S31的输出结果;S321. ART iterative reconstruction, wherein the initial image is the output result of S31;
S322.对ART结果进行最小化光滑处理,来进一步抑制伪影和噪声,并进行平滑处理;当达到一定的迭代次数NTot时停止迭代,否则重复步骤S31-S32。S322. Carry out the ART result Minimize smoothing to further suppress artifacts and noise, and perform smoothing; stop iteration when a certain number of iterations N Tot is reached, otherwise repeat steps S31-S32.
可选的,所述S4具体为:当步骤S3中的迭代算法停止迭代时,输出重建图像。Optionally, said S4 is specifically: when the iterative algorithm in step S3 stops iterating, outputting the reconstructed image.
本发明的有益效果在于:本发明考虑发明考虑图像在非下采样轮廓波变换和图像梯度变换下的稀疏性,利用非下采样轮廓波变换的多尺度、多分辨率分解和伪影方向性特点,设立非下采样轮廓波变换的L0范数最小化和图像梯度的L0范数2个优化目标,建立了多目标优化重建模型。本发明为了抑制噪声、方向性伪影和保护边界,通过在ART算法基础上对非下采样轮廓波变换域的高频和低频部分进行硬阈值处理;为了进一步抑制伪影和噪声且使得重建图像变得光滑,在ART算法基础上进行图像梯度L0最小化处理。本发明公开的极大极小化的多目标有限角CT图像重建方法,从多目标角度出发,建立了多目标优化模型,并利用极大极小化方法求解多目标模型,其中包含ART迭代、非下采样轮廓波变换域的硬阈值处理,图像梯度的L0最小化处理。通过这种极大极小化多目标方法,在保护CT图像的边界同时对有限角伪影和噪声进行有效地抑制,从而很大程度地提高CT重建图像的质量。The beneficial effects of the present invention are: the present invention considers the sparsity of the image under non-subsampling contourlet transformation and image gradient transformation, and utilizes the multi-scale, multi-resolution decomposition and artifact directionality characteristics of non-subsampling contourlet transformation , setting up two optimization objectives of the non-subsampled contourlet transform L0 norm minimization and the L0 norm of the image gradient, and established a multi-objective optimization reconstruction model. In order to suppress noise, directional artifacts and protect boundaries, the present invention performs hard threshold processing on the high-frequency and low-frequency parts of the non-subsampled contourlet transform domain on the basis of the ART algorithm; in order to further suppress artifacts and noise and make the reconstructed image It becomes smooth, and the image gradient L0 is minimized on the basis of the ART algorithm. The multi-objective limited-angle CT image reconstruction method of maximization and minimization disclosed by the present invention establishes a multi-objective optimization model from the perspective of multi-objectives, and uses the maximization and minimization method to solve the multi-objective model, which includes ART iteration, Hard thresholding in the non-subsampled contourlet transform domain, L0 minimization of image gradients. Through this maximin-minimum multi-object method, while protecting the boundaries of CT images, limited-angle artifacts and noises are effectively suppressed, thereby improving the quality of CT reconstruction images to a great extent.
本发明的其他优点、目标和特征在某种程度上将在随后的说明书中进行阐述,并且在某种程度上,基于对下文的考察研究对本领域技术人员而言将是显而易见的,或者可以从本发明的实践中得到教导。本发明的目标和其他优点可以通过下面的说明书来实现和获得。Other advantages, objects and features of the present invention will be set forth in the following description to some extent, and to some extent, will be obvious to those skilled in the art based on the investigation and research below, or can be obtained from It is taught in the practice of the present invention. The objects and other advantages of the invention may be realized and attained by the following specification.
附图说明Description of drawings
为了使本发明的目的、技术方案和优点更加清楚,下面将结合附图对本发明作优选的详细描述,其中:In order to make the purpose of the present invention, technical solutions and advantages clearer, the present invention will be described in detail below in conjunction with the accompanying drawings, wherein:
图1为基于极大极小化的多目标有限角CT图像重建方法的几何结构示意图;Fig. 1 is a schematic diagram of the geometric structure of a multi-target limited-angle CT image reconstruction method based on maximin minimization;
图2为基于极大极小化的多目标有限角CT图像重建方法的流程图。Fig. 2 is a flowchart of a multi-target limited-angle CT image reconstruction method based on maximin minimization.
具体实施方式Detailed ways
以下通过特定的具体实例说明本发明的实施方式,本领域技术人员可由本说明书所揭露的内容轻易地了解本发明的其他优点与功效。本发明还可以通过另外不同的具体实施方式加以实施或应用,本说明书中的各项细节也可以基于不同观点与应用,在没有背离本发明的精神下进行各种修饰或改变。需要说明的是,以下实施例中所提供的图示仅以示意方式说明本发明的基本构想,在不冲突的情况下,以下实施例及实施例中的特征可以相互组合。Embodiments of the present invention are described below through specific examples, and those skilled in the art can easily understand other advantages and effects of the present invention from the content disclosed in this specification. The present invention can also be implemented or applied through other different specific implementation modes, and various modifications or changes can be made to the details in this specification based on different viewpoints and applications without departing from the spirit of the present invention. It should be noted that the diagrams provided in the following embodiments are only schematically illustrating the basic concept of the present invention, and the following embodiments and the features in the embodiments can be combined with each other in the case of no conflict.
其中,附图仅用于示例性说明,表示的仅是示意图,而非实物图,不能理解为对本发明的限制;为了更好地说明本发明的实施例,附图某些部件会有省略、放大或缩小,并不代表实际产品的尺寸;对本领域技术人员来说,附图中某些公知结构及其说明可能省略是可以理解的。Wherein, the accompanying drawings are for illustrative purposes only, and represent only schematic diagrams, rather than physical drawings, and should not be construed as limiting the present invention; in order to better illustrate the embodiments of the present invention, some parts of the accompanying drawings may be omitted, Enlargement or reduction does not represent the size of the actual product; for those skilled in the art, it is understandable that certain known structures and their descriptions in the drawings may be omitted.
本发明实施例的附图中相同或相似的标号对应相同或相似的部件;在本发明的描述中,需要理解的是,若有术语“上”、“下”、“左”、“右”、“前”、“后”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本发明和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此附图中描述位置关系的用语仅用于示例性说明,不能理解为对本发明的限制,对于本领域的普通技术人员而言,可以根据具体情况理解上述术语的具体含义。In the drawings of the embodiments of the present invention, the same or similar symbols correspond to the same or similar components; , "front", "rear" and other indicated orientations or positional relationships are based on the orientations or positional relationships shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred devices or elements must It has a specific orientation, is constructed and operated in a specific orientation, so the terms describing the positional relationship in the drawings are for illustrative purposes only, and should not be construed as limiting the present invention. For those of ordinary skill in the art, the understanding of the specific meaning of the above terms.
图1为基于极大极小化的多目标有限角CT图像重建方法的几何结构示意图。如图所示:以射线源S到旋转中心O建立右手直角坐标系O-xy,y轴过旋转中心O与射线源S的直线,且旋转中心O到射线源S的方向为正方向,x轴垂直于y轴且向右为其正方向。(x,y)是被重建像素J的坐标,SL表示经过被重建点J的一条射线。a轴表示探测器的探测单元对应位置且正方向与x轴一致,(a,s)表示投影视角指标s和探测器位置a构成的坐标。Figure 1 is a schematic diagram of the geometric structure of a multi-target limited-angle CT image reconstruction method based on maximin minimization. As shown in the figure: establish a right-handed rectangular coordinate system O-xy from the ray source S to the rotation center O, the y-axis passes through the line between the rotation center O and the ray source S, and the direction from the rotation center O to the ray source S is the positive direction, x The axis is perpendicular to the y-axis and to the right is its positive direction. (x, y) is the coordinate of the reconstructed pixel J, and SL represents a ray passing through the reconstructed point J. The a-axis represents the corresponding position of the detection unit of the detector and the positive direction is consistent with the x-axis, and (a, s) represents the coordinate formed by the projection viewing angle index s and the detector position a.
图2为基于极大极小化的多目标有限角CT图像重建方法的流程图,如图所示:基于极大极小化的多目标有限角CT图像重建方法包括以下步骤:Fig. 2 is the flowchart of the multi-objective limited-angle CT image reconstruction method based on maximization, as shown in the figure: the multi-objective limited-angle CT image reconstruction method based on maximum minimization comprises the following steps:
S1.采集投影数据:将射线源绕旋转中心沿着扫描轨道旋转有限的角度来获得不完备的投影数据;S1. Acquisition of projection data: rotate the ray source around the rotation center along the scanning track for a limited angle to obtain incomplete projection data;
S2.建立多目标有限角CT图像重建模型:采用离散模型进行重建时,首先需要将如图1所示的所有坐标(x,y)对应的f(x,y)按照y的维度重排成一个1维向量f,其维数为N×1,其中N=n1×n2,n1为f(x,y)在x方向的维数,n2为f(x,y)在y方向的维数。然后,将所有坐标(a,s)对应投影数据gδ(a,s)按照s的维度重排成一个1维向量gδ,列向量gδ的维数为M×1,其中M=m1×m2,m1为gδ(a,s)在a方向的维数,m2为gδ(a,s)在s方向的维数。按照本发明考虑采用非下采样轮廓波变换将重建图像分解成低频部分和高频部分,使图像进行多尺度、多分辨率分解。为了抑制噪声和伪且避免过光滑导致部分细节丢失,通过对非下采样轮廓波变换的系数进行L0稀疏正则化约束。由于为了保护细节,重建图像可能欠光滑,因此为了使得图像光滑,采用图像梯度的L0正则化进行约束。本发明从多目标角度建立的模型如下:S2. Establish a multi-target limited-angle CT image reconstruction model: when using a discrete model for reconstruction, first of all, it is necessary to rearrange f(x, y) corresponding to all coordinates (x, y) shown in Figure 1 according to the dimension of y into A 1-dimensional vector f, its dimension is N×1, where N=n 1 ×n 2 , n 1 is the dimension of f(x,y) in the x direction, n 2 is the dimension of f(x,y) in y The dimensionality of the direction. Then, rearrange the projection data g δ (a, s) corresponding to all coordinates (a, s) into a 1-dimensional vector g δ according to the dimension of s, and the dimension of the column vector g δ is M×1, where M=m 1 ×m 2 , m 1 is the dimension of g δ (a, s) in the a direction, m 2 is the dimension of g δ (a, s) in the s direction. According to the present invention, non-subsampling contourlet transformation is considered to decompose the reconstructed image into low-frequency part and high-frequency part, so that the image can be decomposed into multi-scale and multi-resolution. In order to suppress noise and artifacts and avoid loss of some details caused by over-smoothing, the L0 sparse regularization constraint is applied to the coefficients of the non-subsampled contourlet transform. Since the reconstructed image may be undersmooth in order to preserve the details, in order to make the image smooth, the L0 regularization of the image gradient is used for constraints. The model that the present invention sets up from multi-objective angle is as follows:
其中A∈RM×N是有限角CT系统矩阵,f∈RN×1是待重建图像,gδ∈RM×1是有限角CT投影数据,Ω是凸集(Ω:={f|f≥0})。λ是松弛参数,W是非下采样轮廓波变换,i是子带的索引。||β||0是统计β的非0元素个数,▽β=(▽xβ,▽yβ),▽xβ,▽yβ的分量形式为(▽xβ)i′,j′=βi′,j′-βi′-1,j′,(▽yβ)i′,j′=βi′,j′-βi′,j′-1。当做非下采样轮廓波变换时,将f重排成1个2维矩阵f(x,y),然后对该2维矩阵做非下采样轮廓波变换,当做完非下采样轮廓波反变换后,重新将f(x,y)按照y的维度重排成一个1维向量f。where A∈R M×N is the finite-angle CT system matrix, f∈R N×1 is the image to be reconstructed, g δ ∈ R M×1 is the finite-angle CT projection data, and Ω is a convex set (Ω:={f| f≥0}). λ is the relaxation parameter, W is the non-subsampled contourlet transform, and i is the subband index. ||β|| 0 is the number of non-zero elements of statistical β, ▽β=(▽ x β,▽ y β), the component form of ▽ x β,▽ y β is (▽ x β) i′,j′ =β i',j' -β i'-1,j' ,(▽ y β) i',j' =β i',j' -β i',j'-1 . When doing non-subsampled contourlet transformation, rearrange f into a 2-dimensional matrix f(x,y), and then perform non-subsampled contourlet transformation on the 2-dimensional matrix. After the non-subsampled contourlet inverse transformation is completed , rearrange f(x,y) into a 1-dimensional vector f according to the dimension of y.
S3.有限角CT迭代重建:根据建立的模型(1),采用极大极小化方法求解模型(1);S3. Limited-angle CT iterative reconstruction: according to the established model (1), the model (1) is solved by the method of maximization and minimization;
其中步骤S3有限角CT迭代重建具体过程为:The specific process of step S3 finite-angle CT iterative reconstruction is as follows:
首先,将模型(1)通过极大极小化方法转换成单目标优化模型,其形式如下:First, the model (1) is transformed into a single-objective optimization model through the maximin method, and its form is as follows:
然后,为了有效求解单目标优化模型,取λ为两个特殊的值,首先λ=1,求解对应的优化问题;然后λ=0,再求解对应的优化问题。为了使得最终的解收敛,重复上述λ的取值过程。于是单目标优化模型简化如下形式:Then, in order to effectively solve the single-objective optimization model, λ is taken as two special values. First, λ=1 to solve the corresponding optimization problem; then λ=0 to solve the corresponding optimization problem. In order to make the final solution converge, repeat the above process of λ value selection. So the single-objective optimization model is simplified as follows:
模型(3)等价如下形式:Model (3) is equivalent to the following form:
5)当λ=1时,为了求解(4)中的第一个带约束的优化模型,转换成如下形式:5) When λ=1, in order to solve the first optimization model with constraints in (4), it is converted into the following form:
其中||x||D=<Dx,x>。D是一个对角矩阵,其对角元素为且对所有i′=1,2,...,M,γi是正则化参数,再采用交替方向迭代法(ADMM)求解模型(5),其迭代格式如下:where ||x|| D =<Dx,x>. D is a diagonal matrix whose diagonal elements are And for all i'=1,2,...,M, γ i is the regularization parameter, and then the model (5) is solved by the alternating direction iterative method (ADMM), and the iterative format is as follows:
t是ADMM算法引入的参数。t is a parameter introduced by the ADMM algorithm.
为了避免关于第一个变量f的子问题中求系统矩阵A的逆或者采用迭代法求解子问题的不足,本发明嵌入临近交替线性化的思想,将迭代格式(6)转换为临近交替线性化的ADMM迭代格式,具体如下:In order to avoid the deficiency of seeking the inverse of the system matrix A in the subproblem about the first variable f or adopting the iterative method to solve the subproblems, the present invention embeds the idea of adjacent alternating linearization, and converts the iterative format (6) into adjacent alternating linearization The ADMM iteration format is as follows:
迭代格式(7)中是临近线性化引入的松弛参数。(7)中为ART迭代更新格式。通过临近交替线性化巧妙地将经典的ART迭代算法融入其中。In iterative format (7) is the slack parameter introduced near linearization. (7) Update format for ART iterations. The classic ART iterative algorithm is subtly integrated into it by adjacent alternating linearization.
则求出迭代格式(7)的子问题最优解,迭代格式如下所示:Then find the optimal solution to the subproblem of the iterative format (7), and the iterative format is as follows:
其中(WT表示非下采样轮廓波反变换), where (W T represents the non-subsampled contourlet inverse transform),
6)当λ=0时,为了求解(4)中的第二个带约束的优化模型,转换成如下形式:6) When λ=0, in order to solve the second optimization model with constraints in (4), it is converted into the following form:
其中D是一个对角矩阵,其对角元素为且对所有i′=1,2,...,M,μ是正则化参数,采用临近线性化的思想将问题转化为:where D is a diagonal matrix whose diagonal elements are And for all i'=1,2,...,M, μ is a regularization parameter, using the idea of near linearization to transform the problem into:
其中用L0最小化方法求解(10)式,其迭代格式如下:in Using the L0 minimization method to solve equation (10), the iterative format is as follows:
的迭代形式如下:对所有图像坐标i′,j′ The iterative form of is as follows: For all image coordinates i′, j′
其中表示傅里叶变换,表示傅里叶反变换,表示傅里叶变换的复共轭,▽x,▽y分别表示x,y的梯度算子;β控制相似性的参数,κ(κ>1)表示控制β增长速度的参数;n表示算法的迭代次数,算法的停机标准是β大于迭代前预设的参数βmax,当算法的停机后输出图像为fk+1。in represents the Fourier transform, represents the inverse Fourier transform, Represents the complex conjugate of Fourier transform, ▽ x , ▽ y represent the gradient operators of x and y respectively; β controls The parameter of similarity, κ (κ>1) represents the parameter that controls the growth rate of β; n represents the number of iterations of the algorithm, The stop criterion of the algorithm is that β is greater than the preset parameter β max before iteration, when The output image after the stoppage of the algorithm is f k+1 .
设迭代格式(8)和(11)对应的停机标准为分别达到预先设定的迭代次数Nite1和Nite2,设整个算法的总迭代次数为NTot(tt为总的迭代次数索引),则迭代流程如下:Assuming that the shutdown criteria corresponding to iteration formats (8) and (11) are respectively reaching the preset iteration times N ite1 and N ite2 , and setting the total number of iterations of the entire algorithm as N Tot (tt is the index of the total number of iterations), then The iteration process is as follows:
根据上述方法,步骤S3有限角CT迭代重建包含如下2个子步骤:S31.基于非下采样轮廓波变换的L0正则化图像重建;S32.基于梯度变换的L0正则化图像重建。其中S31包含如下3个子步骤:S311.ART迭代重建和非下采样轮廓波反变换组合得到初步重建结果;S312.对得到的初步结果在非下采样轮廓波变换域对高频部分和低频部分进行硬阈值处理,来抑制伪影和噪声,与此同时进行边界保护;S313.对偶变量v更新。其中S32包含如下2个子步骤:S321.ART迭代重建,其中初始图像为S31的输出结果;S322.对ART结果进行最小化光滑处理,来进一步抑制伪影和噪声,并进行平滑处理。当达到一定的迭代次数NTot时停止迭代,否则重复步骤S31-S32。According to the above method, step S3 finite-angle CT iterative reconstruction includes the following two sub-steps: S31. L0 regularized image reconstruction based on non-subsampled contourlet transformation; S32. L0 regularized image reconstruction based on gradient transformation. Among them, S31 includes the following three sub-steps: S311. ART iterative reconstruction and non-subsampled contourlet inverse transformation combination to obtain preliminary reconstruction results; Hard threshold processing to suppress artifacts and noise, and at the same time perform boundary protection; S313. Dual variable v update. Wherein S32 includes the following two sub-steps: S321. ART iterative reconstruction, wherein the initial image is the output result of S31; S322. Minimize smoothing to further suppress artifacts and noise and smooth. When a certain number of iterations N Tot is reached, the iteration is stopped, otherwise steps S31-S32 are repeated.
S4.输出重建图像。当步骤S3中的迭代算法停止迭代时,输出重建图像。S4. Outputting the reconstructed image. When the iterative algorithm in step S3 stops iterating, the reconstructed image is output.
最后说明的是,以上实施例仅用以说明本发明的技术方案而非限制,尽管参照较佳实施例对本发明进行了详细说明,本领域的普通技术人员应当理解,可以对本发明的技术方案进行修改或者等同替换,而不脱离本技术方案的宗旨和范围,其均应涵盖在本发明的权利要求范围当中。Finally, it is noted that the above embodiments are only used to illustrate the technical solutions of the present invention without limitation. Although the present invention has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present invention can be carried out Modifications or equivalent replacements, without departing from the spirit and scope of the technical solution, should be included in the scope of the claims of the present invention.
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