CN112494340B - A kind of dental bonding pretreatment material and use - Google Patents
A kind of dental bonding pretreatment material and use Download PDFInfo
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- CN112494340B CN112494340B CN202011203053.5A CN202011203053A CN112494340B CN 112494340 B CN112494340 B CN 112494340B CN 202011203053 A CN202011203053 A CN 202011203053A CN 112494340 B CN112494340 B CN 112494340B
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- 239000000463 material Substances 0.000 title claims abstract description 29
- 239000000243 solution Substances 0.000 claims abstract description 648
- 239000000853 adhesive Substances 0.000 claims abstract description 186
- 230000001070 adhesive effect Effects 0.000 claims abstract description 186
- 239000012266 salt solution Substances 0.000 claims abstract description 25
- 229910002056 binary alloy Inorganic materials 0.000 claims abstract description 17
- 229910052784 alkaline earth metal Inorganic materials 0.000 claims abstract description 11
- -1 alkaline earth metal salt Chemical class 0.000 claims abstract description 10
- 239000002244 precipitate Substances 0.000 claims abstract description 7
- 239000000178 monomer Substances 0.000 claims abstract description 6
- 239000007864 aqueous solution Substances 0.000 claims description 368
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 316
- 239000011248 coating agent Substances 0.000 claims description 226
- 238000000576 coating method Methods 0.000 claims description 226
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims description 182
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 116
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims description 110
- 239000001110 calcium chloride Substances 0.000 claims description 110
- 229910001628 calcium chloride Inorganic materials 0.000 claims description 110
- 239000011775 sodium fluoride Substances 0.000 claims description 91
- 235000013024 sodium fluoride Nutrition 0.000 claims description 91
- 239000011259 mixed solution Substances 0.000 claims description 42
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 36
- OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 claims description 36
- 239000000203 mixture Substances 0.000 claims description 21
- RQPZNWPYLFFXCP-UHFFFAOYSA-L barium dihydroxide Chemical compound [OH-].[OH-].[Ba+2] RQPZNWPYLFFXCP-UHFFFAOYSA-L 0.000 claims description 19
- 229910001863 barium hydroxide Inorganic materials 0.000 claims description 19
- DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 claims description 18
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 claims description 18
- 229910052943 magnesium sulfate Inorganic materials 0.000 claims description 18
- 235000019341 magnesium sulphate Nutrition 0.000 claims description 18
- 229910052938 sodium sulfate Inorganic materials 0.000 claims description 18
- 235000011152 sodium sulphate Nutrition 0.000 claims description 18
- LWIHDJKSTIGBAC-UHFFFAOYSA-K tripotassium phosphate Chemical compound [K+].[K+].[K+].[O-]P([O-])([O-])=O LWIHDJKSTIGBAC-UHFFFAOYSA-K 0.000 claims description 16
- WDIHJSXYQDMJHN-UHFFFAOYSA-L barium chloride Chemical compound [Cl-].[Cl-].[Ba+2] WDIHJSXYQDMJHN-UHFFFAOYSA-L 0.000 claims description 10
- 229910001626 barium chloride Inorganic materials 0.000 claims description 10
- 229920006395 saturated elastomer Polymers 0.000 claims description 10
- 229910001631 strontium chloride Inorganic materials 0.000 claims description 10
- AHBGXTDRMVNFER-UHFFFAOYSA-L strontium dichloride Chemical compound [Cl-].[Cl-].[Sr+2] AHBGXTDRMVNFER-UHFFFAOYSA-L 0.000 claims description 10
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 claims description 9
- 229910019142 PO4 Inorganic materials 0.000 claims description 9
- 235000021317 phosphate Nutrition 0.000 claims description 9
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 claims description 9
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- 239000007767 bonding agent Substances 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 7
- 239000010452 phosphate Substances 0.000 claims description 7
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 6
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims description 6
- 235000019797 dipotassium phosphate Nutrition 0.000 claims description 6
- 229910000396 dipotassium phosphate Inorganic materials 0.000 claims description 6
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 5
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims description 5
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims description 5
- 239000003513 alkali Substances 0.000 claims description 5
- 159000000009 barium salts Chemical class 0.000 claims description 5
- 159000000007 calcium salts Chemical class 0.000 claims description 5
- 159000000003 magnesium salts Chemical class 0.000 claims description 5
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 159000000008 strontium salts Chemical class 0.000 claims description 5
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 4
- TWRXJAOTZQYOKJ-UHFFFAOYSA-L Magnesium chloride Chemical compound [Mg+2].[Cl-].[Cl-] TWRXJAOTZQYOKJ-UHFFFAOYSA-L 0.000 claims description 4
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
- IWOUKMZUPDVPGQ-UHFFFAOYSA-N barium nitrate Chemical compound [Ba+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O IWOUKMZUPDVPGQ-UHFFFAOYSA-N 0.000 claims description 4
- ZCCIPPOKBCJFDN-UHFFFAOYSA-N calcium nitrate Chemical compound [Ca+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O ZCCIPPOKBCJFDN-UHFFFAOYSA-N 0.000 claims description 4
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 4
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims description 4
- DHEQXMRUPNDRPG-UHFFFAOYSA-N strontium nitrate Chemical compound [Sr+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O DHEQXMRUPNDRPG-UHFFFAOYSA-N 0.000 claims description 4
- ARCGXLSVLAOJQL-UHFFFAOYSA-N trimellitic acid Chemical compound OC(=O)C1=CC=C(C(O)=O)C(C(O)=O)=C1 ARCGXLSVLAOJQL-UHFFFAOYSA-N 0.000 claims description 4
- 150000001342 alkaline earth metals Chemical class 0.000 claims description 3
- CFKBCVIYTWDYRP-UHFFFAOYSA-N 10-phosphonooxydecyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCCCCCCCCCOP(O)(O)=O CFKBCVIYTWDYRP-UHFFFAOYSA-N 0.000 claims description 2
- LYRWNAXKUQELGU-UHFFFAOYSA-N 2-Methacryloyloxyethyl phenyl phosphate Chemical compound CC(=C)C(=O)OCCOP(O)(=O)OC1=CC=CC=C1 LYRWNAXKUQELGU-UHFFFAOYSA-N 0.000 claims description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 2
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 claims description 2
- 239000004254 Ammonium phosphate Substances 0.000 claims description 2
- 239000004115 Sodium Silicate Substances 0.000 claims description 2
- 238000010306 acid treatment Methods 0.000 claims description 2
- 239000001099 ammonium carbonate Substances 0.000 claims description 2
- 235000012501 ammonium carbonate Nutrition 0.000 claims description 2
- 229910000148 ammonium phosphate Inorganic materials 0.000 claims description 2
- 235000019289 ammonium phosphates Nutrition 0.000 claims description 2
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims description 2
- 235000011130 ammonium sulphate Nutrition 0.000 claims description 2
- 150000008064 anhydrides Chemical class 0.000 claims description 2
- VSGNNIFQASZAOI-UHFFFAOYSA-L calcium acetate Chemical compound [Ca+2].CC([O-])=O.CC([O-])=O VSGNNIFQASZAOI-UHFFFAOYSA-L 0.000 claims description 2
- 239000001639 calcium acetate Substances 0.000 claims description 2
- 235000011092 calcium acetate Nutrition 0.000 claims description 2
- 229960005147 calcium acetate Drugs 0.000 claims description 2
- NKWPZUCBCARRDP-UHFFFAOYSA-L calcium bicarbonate Chemical compound [Ca+2].OC([O-])=O.OC([O-])=O NKWPZUCBCARRDP-UHFFFAOYSA-L 0.000 claims description 2
- 229910000020 calcium bicarbonate Inorganic materials 0.000 claims description 2
- FNAQSUUGMSOBHW-UHFFFAOYSA-H calcium citrate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O.[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O FNAQSUUGMSOBHW-UHFFFAOYSA-H 0.000 claims description 2
- 239000001354 calcium citrate Substances 0.000 claims description 2
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims description 2
- 239000004227 calcium gluconate Substances 0.000 claims description 2
- 235000013927 calcium gluconate Nutrition 0.000 claims description 2
- 229960004494 calcium gluconate Drugs 0.000 claims description 2
- 239000000920 calcium hydroxide Substances 0.000 claims description 2
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims description 2
- MKJXYGKVIBWPFZ-UHFFFAOYSA-L calcium lactate Chemical compound [Ca+2].CC(O)C([O-])=O.CC(O)C([O-])=O MKJXYGKVIBWPFZ-UHFFFAOYSA-L 0.000 claims description 2
- 239000001527 calcium lactate Substances 0.000 claims description 2
- 235000011086 calcium lactate Nutrition 0.000 claims description 2
- 229960002401 calcium lactate Drugs 0.000 claims description 2
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 claims description 2
- MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 claims description 2
- DJMIKAGANCZWLL-UHFFFAOYSA-N dihydroxy hydrogen phosphate Chemical compound OOP(O)(=O)OO DJMIKAGANCZWLL-UHFFFAOYSA-N 0.000 claims description 2
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 2
- TVACALAUIQMRDF-UHFFFAOYSA-N dodecyl dihydrogen phosphate Chemical compound CCCCCCCCCCCCOP(O)(O)=O TVACALAUIQMRDF-UHFFFAOYSA-N 0.000 claims description 2
- 238000011010 flushing procedure Methods 0.000 claims description 2
- QWDJLDTYWNBUKE-UHFFFAOYSA-L magnesium bicarbonate Chemical compound [Mg+2].OC([O-])=O.OC([O-])=O QWDJLDTYWNBUKE-UHFFFAOYSA-L 0.000 claims description 2
- 229910000022 magnesium bicarbonate Inorganic materials 0.000 claims description 2
- 235000014824 magnesium bicarbonate Nutrition 0.000 claims description 2
- 239000002370 magnesium bicarbonate Substances 0.000 claims description 2
- 229910001629 magnesium chloride Inorganic materials 0.000 claims description 2
- 229910000403 monosodium phosphate Inorganic materials 0.000 claims description 2
- 235000019799 monosodium phosphate Nutrition 0.000 claims description 2
- 150000003013 phosphoric acid derivatives Chemical class 0.000 claims description 2
- 229910000027 potassium carbonate Inorganic materials 0.000 claims description 2
- 239000011698 potassium fluoride Substances 0.000 claims description 2
- 235000003270 potassium fluoride Nutrition 0.000 claims description 2
- 229910000160 potassium phosphate Inorganic materials 0.000 claims description 2
- 235000011009 potassium phosphates Nutrition 0.000 claims description 2
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 claims description 2
- 229910052939 potassium sulfate Inorganic materials 0.000 claims description 2
- 235000011151 potassium sulphates Nutrition 0.000 claims description 2
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 2
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 claims description 2
- 239000001488 sodium phosphate Substances 0.000 claims description 2
- 229910000162 sodium phosphate Inorganic materials 0.000 claims description 2
- 235000011008 sodium phosphates Nutrition 0.000 claims description 2
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 claims description 2
- 229910052911 sodium silicate Inorganic materials 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- UUCCCPNEFXQJEL-UHFFFAOYSA-L strontium dihydroxide Chemical compound [OH-].[OH-].[Sr+2] UUCCCPNEFXQJEL-UHFFFAOYSA-L 0.000 claims description 2
- 229910001866 strontium hydroxide Inorganic materials 0.000 claims description 2
- WJMMDJOFTZAHHS-UHFFFAOYSA-L strontium;carbonic acid;carbonate Chemical compound [Sr+2].OC([O-])=O.OC([O-])=O WJMMDJOFTZAHHS-UHFFFAOYSA-L 0.000 claims description 2
- 235000013337 tricalcium citrate Nutrition 0.000 claims description 2
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Substances [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims 1
- 235000010216 calcium carbonate Nutrition 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- PNJWIWWMYCMZRO-UHFFFAOYSA-N pent‐4‐en‐2‐one Natural products CC(=O)CC=C PNJWIWWMYCMZRO-UHFFFAOYSA-N 0.000 claims 1
- RLQWHDODQVOVKU-UHFFFAOYSA-N tetrapotassium;silicate Chemical compound [K+].[K+].[K+].[K+].[O-][Si]([O-])([O-])[O-] RLQWHDODQVOVKU-UHFFFAOYSA-N 0.000 claims 1
- 210000004268 dentin Anatomy 0.000 abstract description 205
- 239000011159 matrix material Substances 0.000 abstract description 34
- 239000002105 nanoparticle Substances 0.000 abstract description 15
- 238000011065 in-situ storage Methods 0.000 abstract description 14
- 102000008186 Collagen Human genes 0.000 abstract description 11
- 108010035532 Collagen Proteins 0.000 abstract description 11
- 229920001436 collagen Polymers 0.000 abstract description 11
- 230000035945 sensitivity Effects 0.000 abstract description 5
- 150000003839 salts Chemical class 0.000 abstract description 4
- 239000002131 composite material Substances 0.000 abstract description 2
- 239000006185 dispersion Substances 0.000 abstract description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 300
- 238000005406 washing Methods 0.000 description 300
- 238000005530 etching Methods 0.000 description 152
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 150
- 238000005286 illumination Methods 0.000 description 130
- 238000001228 spectrum Methods 0.000 description 77
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- 238000007664 blowing Methods 0.000 description 20
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 12
- 235000019796 monopotassium phosphate Nutrition 0.000 description 12
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 description 12
- 238000005516 engineering process Methods 0.000 description 6
- 230000008021 deposition Effects 0.000 description 5
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- 239000000835 fiber Substances 0.000 description 5
- 230000002209 hydrophobic effect Effects 0.000 description 5
- 230000008439 repair process Effects 0.000 description 5
- 230000036571 hydration Effects 0.000 description 4
- 238000006703 hydration reaction Methods 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
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- 230000008859 change Effects 0.000 description 3
- 210000003298 dental enamel Anatomy 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 2
- 238000004833 X-ray photoelectron spectroscopy Methods 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 229960005069 calcium Drugs 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 238000001816 cooling Methods 0.000 description 2
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- 230000002328 demineralizing effect Effects 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 229910052731 fluorine Inorganic materials 0.000 description 2
- 239000011737 fluorine Substances 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000012876 topography Methods 0.000 description 2
- 238000009827 uniform distribution Methods 0.000 description 2
- RMCCONIRBZIDTH-UHFFFAOYSA-N 2-(2-methylprop-2-enoyloxy)ethyl 1,3-dioxo-2-benzofuran-5-carboxylate Chemical compound CC(=C)C(=O)OCCOC(=O)C1=CC=C2C(=O)OC(=O)C2=C1 RMCCONIRBZIDTH-UHFFFAOYSA-N 0.000 description 1
- QCUCAQZMPVIYAJ-UHFFFAOYSA-N 2-(4-methyl-1h-indol-3-yl)ethanamine Chemical compound CC1=CC=CC2=C1C(CCN)=CN2 QCUCAQZMPVIYAJ-UHFFFAOYSA-N 0.000 description 1
- ASMQGLCHMVWBQR-UHFFFAOYSA-N Diphenyl phosphate Chemical compound C=1C=CC=CC=1OP(=O)(O)OC1=CC=CC=C1 ASMQGLCHMVWBQR-UHFFFAOYSA-N 0.000 description 1
- 239000004111 Potassium silicate Substances 0.000 description 1
- 229910001420 alkaline earth metal ion Inorganic materials 0.000 description 1
- 150000001450 anions Chemical class 0.000 description 1
- JXRVKYBCWUJJBP-UHFFFAOYSA-L calcium;hydrogen sulfate Chemical compound [Ca+2].OS([O-])(=O)=O.OS([O-])(=O)=O JXRVKYBCWUJJBP-UHFFFAOYSA-L 0.000 description 1
- 150000001768 cations Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 239000003479 dental cement Substances 0.000 description 1
- 239000005548 dental material Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- ZJXZSIYSNXKHEA-UHFFFAOYSA-N ethyl dihydrogen phosphate Chemical compound CCOP(O)(O)=O ZJXZSIYSNXKHEA-UHFFFAOYSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000001000 micrograph Methods 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- VOFUROIFQGPCGE-UHFFFAOYSA-N nile red Chemical compound C1=CC=C2C3=NC4=CC=C(N(CC)CC)C=C4OC3=CC(=O)C2=C1 VOFUROIFQGPCGE-UHFFFAOYSA-N 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
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- NNHHDJVEYQHLHG-UHFFFAOYSA-N potassium silicate Chemical compound [K+].[K+].[O-][Si]([O-])=O NNHHDJVEYQHLHG-UHFFFAOYSA-N 0.000 description 1
- 229910052913 potassium silicate Inorganic materials 0.000 description 1
- 235000019353 potassium silicate Nutrition 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000001044 red dye Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 238000004381 surface treatment Methods 0.000 description 1
- 238000009864 tensile test Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/30—Compositions for temporarily or permanently fixing teeth or palates, e.g. primers for dental adhesives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
- A61K6/84—Preparations for artificial teeth, for filling teeth or for capping teeth comprising metals or alloys
Landscapes
- Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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Abstract
The invention provides a dental bonding pretreatment material and application thereof, wherein the dental bonding pretreatment material comprises a binary system and a ternary system, wherein the binary system and the ternary system are composed of a solution (A) of soluble alkaline earth metal salt, a solution (B) which is used for generating alkaline earth metal salt precipitate with the solution (A), and a solution (C) of organic monomer. The pretreatment material is treated by soluble alkaline earth salt which reacts with non-collagen in the demineralized dentin organic matrix and is then treated by soluble salt solution which can react with the alkaline earth salt to form precipitate, insoluble nano particles can be rapidly deposited in situ in the demineralized dentin organic matrix, and the dentin organic matrix structure is reinforced, so that the permeation and dispersion of the adhesive to the maximum extent are promoted, a uniform and stable novel 3D porous composite structure is formed, and the adhesive can obtain higher adhesive strength and adhesive durability when being applied. Even if the tooth surface is completely dried when the adhesive is coated, higher adhesive strength and adhesive durability can be obtained, and the technical sensitivity of clinical operation is greatly reduced.
Description
Technical Field
The invention belongs to the field of dental bonding materials, and relates to a dental bonding pretreatment material and application thereof in preparation of a dental bonding pretreatment agent. The dental adhesion pretreatment material is mainly used for pretreating the surface of a tooth body in the oral adhesion process, so that the adhesion effect is improved, and the technical sensitivity of adhesion operation is reduced.
Background
In dental medicine, in order to repair a tooth defect, either direct repair or indirect repair, an adhesive material is used to bond the repair material to a tooth tissue.
The tooth tissue is used as one of bonding surfaces and is divided into two parts of enamel and dentin, the enamel structure is simple, the pure enamel bonding is difficult to meet clinically, and the bonding is easy to realize. The dentin has a complex structure, is the most common and important bonding mode in dentistry clinic, and the surface treatment mode determines the bonding strength and the bonding durability and directly influences the clinical restoration effect.
At present, the clinical dentin bonding technology is a wet bonding technology, which is applied to the fifty years of the last century and is molded in the ninety years of the last century, namely, after the dentin is subjected to acid etching and demineralization treatment, the surface of the demineralized dentin is kept in a slightly wet or moist state so as to keep the fluffy state of collagen fibers in an organic matrix of the demineralized dentin and provide space for the permeation of a subsequent adhesive; meanwhile, a large amount of amphiphilic micromolecular monomers are added into the hydrophobic adhesive, so that the adhesive can effectively permeate into the demineralized dentin organic matrix, and based on the wet adhesion technology, the dentin adhesion obtains good, repeatable and reliable adhesion strength, and adhesion reparation is formed on the basis.
Although the initial bonding strength of the wet bonding technology is high, the non-collagen in the demineralized dentin matrix is rich in negative charge polar groups such as phosphate radical, carboxyl group and the like, so that the non-collagen has very strong hydration capacity, under the physiological environment, the non-collagen forms hydrogel-like structures on the surface of the dentin collagen fibers, the structures form structures similar to 'molecular sieves', the permeation and uniform distribution of key hydrophobic components of the adhesive in the demineralized dentin collagen fiber network are seriously hindered, the formed tooth body-adhesive bonding interface-hybrid layer is full of defects, various problems can be caused when the adhesive is used for a long time in a complex oral environment, and the falling of a prosthesis is also often caused.
Furthermore, this technique requires that the surface of the tooth to be coated with the adhesive be kept wet during the operation, while excessively wet or excessively dry surfaces of the tooth affect the adhesion effect, and have great technical sensitivity.
Meanwhile, a large amount of adhesives of various types are clinically used, the formula is different, the clinical use methods are different, the final clinical results are different, great uncertainty is brought to the clinical treatment effect of a patient, high requirements are required for the technical level of a clinician, and great pressure is brought to the use of the clinician.
Replacement of the prosthesis due to reduced durability of the adhesive bond places a significant burden on the health, economic status, and medical care of the patient. Therefore, in order to improve the adhesion durability, development of a dental pretreatment system for oral adhesion having a new mechanism of action in conformity with the dentin characteristics is strongly required.
Disclosure of Invention
The invention aims to provide a dental bonding pretreatment material, which is an in-situ deposited alkaline-earth insoluble nano particle and is used for dental restoration bonding, the technical sensitivity of dental bonding is reduced, clinical differences among various adhesives are eliminated, high bonding force is obtained, and the bonding durability is improved.
The dental bonding pretreatment material consists of a binary system and a ternary system, wherein the binary system and the ternary system consist of a solution (A), a solution (B) and a solution (C) which are packaged independently.
The binary system consists of a solution (A) and a solution (B), wherein the solution (A) is a soluble alkaline earth metal salt solution, and the solution (B) is a soluble solution which can react with the solution (A) to generate alkaline earth metal salt precipitates.
The ternary system consists of solution A, solution B and solution C, the solution A is soluble alkali earth metal salt solution, the solution B is soluble solution capable of reacting with the solution A to produce alkali earth metal salt precipitate, and the solution C is organic monomer solution capable of chelating with insoluble alkali earth metal salt precipitate metal cation.
The solution (A) is soluble magnesium salt solution, calcium salt solution, strontium salt solution, barium salt solution, or mixed solution of 2 or more than 2 solutions.
Wherein, the mass fraction of the solution (A) can be 0.0001% to saturated concentration soluble magnesium salt solution, including but not limited to magnesium chloride aqueous solution, magnesium sulfate aqueous solution, magnesium bicarbonate aqueous solution, including one or more of the above solution mixture, and the optimal concentration of the soluble magnesium salt solution is 0.01-2% by mass fraction.
The solution (a) may be 0.0001 wt% to saturation concentration soluble calcium salt solution, including but not limited to calcium chloride aqueous solution, calcium sulfate aqueous solution, calcium hydrogen sulfate aqueous solution, calcium bicarbonate aqueous solution, calcium nitrate aqueous solution, calcium hydroxide aqueous solution, calcium gluconate aqueous solution, calcium acetate aqueous solution, calcium lactate aqueous solution, and calcium citrate aqueous solution, including one or more of the above solution mixtures, and the optimal concentration of the soluble calcium salt solution is 0.01-2 wt%.
The solution (a) may be a soluble strontium salt solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to strontium chloride aqueous solution, strontium bicarbonate aqueous solution, strontium nitrate aqueous solution, strontium hydroxide aqueous solution, including one or more of the above solution mixtures, and the optimal concentration of the soluble strontium salt solution is 0.01-2% by mass fraction.
The solution (A) can be 0.0001% by mass to saturated concentration soluble barium salt solution, including but not limited to barium chloride aqueous solution, barium nitrate aqueous solution, barium hydroxide aqueous solution, and mixture of one or more of the above solutions, and the optimal concentration of the soluble barium salt solution is 0.01-2% by mass.
The solution (B) is a soluble fluoride solution, a soluble sulfate solution, a soluble carbonate solution, a soluble silicate solution, a soluble phosphate solution, a soluble alkali solution, or a mixed solution of 2 or more solutions thereof.
The solution (B) may be a soluble fluoride solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to sodium fluoride aqueous solution, potassium fluoride aqueous solution, ammonium fluoride aqueous solution, including one or more of the above-mentioned solution mixtures, and the optimal concentration of the soluble fluoride solution is 0.01-2% by mass fraction.
Wherein the solution (B) can be soluble sulfate solution with mass fraction of 0.0001% to saturation concentration, including but not limited to sodium sulfate aqueous solution, potassium sulfate aqueous solution, zinc sulfate aqueous solution, ammonium sulfate aqueous solution, including one or more of the above solutions mixture, and the optimal concentration of the soluble sulfate solution is 0.01-2% by mass fraction.
The solution (B) can be a soluble carbonate solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to sodium carbonate aqueous solution, potassium carbonate aqueous solution and ammonium carbonate aqueous solution, and the optimal concentration of the soluble carbonate solution containing one or more of the above solution mixtures is 0.01-2% by mass fraction.
The solution (B) can be a soluble silicate solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to soluble silicate, including but not limited to sodium silicate aqueous solution, potassium silicate aqueous solution, ammonium silicate aqueous solution, including one or more of the above solution mixtures, and the optimal concentration of the soluble silicate solution is 0.01-2% by mass fraction.
The solution (B) can be a soluble phosphate solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to soluble phosphates, including but not limited to sodium monohydrogen phosphate aqueous solution, potassium monohydrogen phosphate aqueous solution, sodium dihydrogen phosphate aqueous solution, potassium phosphate, sodium phosphate, ammonium phosphate, including one or more of the above solution mixtures, and the optimal concentration of the soluble phosphate solution is 0.01-2% by mass.
The solution (B) can be a soluble alkali solution with a mass fraction of 0.0001% to a saturated concentration, including but not limited to sodium hydroxide and potassium hydroxide containing one or more of the above solution mixtures, and the optimal concentration of the soluble alkali solution is 0.01-2% by mass fraction.
The organic monomer solution of the solution (C) is one or more of 10-methacryloyloxydecyl phosphate (10-MDP), 2,4, 6-trimethylphenyl 2- [4- (dihydroxyphosphoric acid) -2-oxabutyl ] acrylate (MAEPA), ethyl 2- [4- (dihydroxyphosphoryl) -2-oxabutyl ] acrylate (EAEPA), n-dodecyl dihydrogen phosphate, ethyl dihydrogen phosphate, 4-methacryloyloxyethyl trimellitic acid (4-MET), 4-methacryloyloxytrimellitic anhydride (4-META) and 2-methacryloyloxyethyl Phenyl hydrogen phosphate (Phenyl-P) with the mass fraction of 0.0001% to the saturation concentration, and the solvent includes but is not limited to water, ethanol, acetone or a mixed solution thereof, the optimal concentration is 0.0001-15% by mass.
The invention also aims to provide application of the dental adhesion pretreatment material in preparing a dental surface adhesion pretreatment agent in an oral adhesion process. The pretreatment agent provided by the present specification is used after the clinical acid treatment of the tooth surface and before the application of the adhesive. The solution (A), the solution (B) and the solution (C) in the pretreating agent are packaged separately.
When the dental adhesion pretreatment material of the binary system is used, the solution (A) is applied, the solution (B) is applied, and then the adhesive is applied to perform dental adhesion.
When the ternary system dental pretreatment adhesive material is used, the solution (A) is coated firstly, then the solution (B) is coated, after the water vapor flushing, the solution (C) is coated, and then the adhesive is coated to carry out the adhesion of the tooth body.
When the binary system or ternary system dental pretreatment adhesive material is used, the solution (A) and the solution (B) can be coated for multiple times in a circulating way.
After the binary system or ternary system dental pretreatment adhesive material is used, the surface of the tooth body to be coated with the adhesive can be kept wet.
After the dental pretreatment adhesive material is applied to the dental material in a binary system or a ternary system, the surface of the tooth body to be coated with the adhesive can be dried.
After the bonding material is subjected to the dental pretreatment of a binary system or a ternary system, the applied dental adhesive can be any existing dentin adhesive.
After the bonding material is subjected to dental pretreatment by using a binary system or a ternary system, the nanoparticles are deposited in situ between and in the dentin collagen fibers and intertwined with the dentin organic matrix.
After the binary system or ternary system dental pretreatment bonding material is used, the surface polarity of the dentin organic matrix is reduced, the surface potential is increased, the hydration capability is weakened, and the interface compatibility of the demineralized dentin organic matrix and the key hydrophobic bonding component in the bonding agent is greatly improved.
After the binary system or ternary system dental pretreatment bonding material is used, the surface area of the dentin organic matrix is increased, the rigidity of the demineralized dentin matrix is increased, and the shrinkage caused by drying can be resisted, so that the dentin bonding is free from dependence on physiological water, and the technical sensitivity of clinical operation of the dentin bonding is reduced.
After the bonding material is subjected to dental pretreatment by using a binary system or a ternary system, the interfacial compatibility of the demineralized dentin organic matrix and the bonding agent is remarkably improved, the redistribution phenomenon of key hydrophobic components of the bonding agent between the bonding layer and the demineralized dentin is greatly relieved, the permeability in the demineralized dentin layer is increased, the content is improved, the distribution is more uniform, the clinical bonding effect of various bonding agents can be improved, and the dependence on the technical level of doctors and the types of the bonding agents is reduced.
Compared with the prior wet bonding technology, the invention is characterized in that after acid etching demineralization treatment and before applying the bonding agent, the surface of a tooth body is pretreated, polar sites are quickly occupied through the interaction of soluble alkaline earth metal salt solution and groups with negative charges, such as phosphate radical, carboxyl, hydroxyl and the like, on non-collagen in a dentin organic matrix, then, insoluble nano particles are formed in situ on the polar sites of the non-collagen by utilizing the in-situ precipitation reaction of anion salt solution which can generate precipitation with alkaline earth metal ions, and the sites of the polar groups on the demineralized dentin organic matrix are occupied to cover the negative charge groups on the surface of the dentin organic matrix, eliminate the hydration capability of the demineralized dentin matrix surface, improve the interface compatibility of the demineralized dentin matrix and key hydrophobic components of the bonding agent and increase the specific surface area of the demineralized dentin matrix, the rigidity of the demineralized organic matrix is enhanced, so that the demineralized organic matrix can keep a porous open structure under the condition of water volatilization and drying, the dependence of a tooth bonding operation technology on water is reduced, meanwhile, the precipitated particles deposited in situ reinforce the dentin organic matrix structure, the permeation and dispersion of the adhesive to the maximum extent are promoted, a uniform and stable novel 3D porous composite structure is formed, and the durability of bonding repair is greatly improved.
Drawings
FIG. 1 is a scanning electron microscope image of the surface topography of the teeth of examples one to three.
FIG. 2 is the results of the spectrometer observation of the fractured surfaces of the teeth according to the first to third embodiments.
FIG. 3 shows the results of X-ray photoelectron spectroscopy on the surface of the tooth according to examples one to three.
FIG. 4 shows the results of the surface potentials of the teeth according to examples one to three.
Fig. 5 shows the mass change of the dentin matrix before and after water absorption in examples one to three.
Fig. 6 shows the specific surface area of the dentin matrix in examples one to three.
Fig. 7 shows the change in the modulus of elasticity and hardness of the dentin matrix in examples one to three.
FIG. 8 shows the cross-sectional thicknesses of the teeth according to the first to third embodiments.
FIG. 9 is a confocal laser observation of the dentin-adhesive bonding interface in the twelfth to fourteenth embodiments.
FIG. 10 shows the tensile strength results for Spectrum Bond adhesives of twelve to fourteen examples.
FIG. 11 shows the results of tensile strength of Single Bond2 adhesives of twelve to fourteen examples.
FIG. 12 shows the results of tensile strength of Single Bond2 adhesives of twelve, fifteen, and sixteen examples.
Detailed Description
The present invention is further illustrated by the following examples, which are included merely to better illustrate the features of the invention and are not to be construed as limiting the scope of the invention as claimed.
Example one
And (3) rinsing with water vapor after the phosphoric acid etching treatment on the surface of the dentin, and keeping the surface wet or drying the surface by blowing.
Example two
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, and keeping the surface wet or drying the surface by blowing.
EXAMPLE III
Rinsing with water vapor after phosphoric acid etching treatment of dentin surface, coating 20 μ l of solution (A) with 1.11% calcium chloride aqueous solution by mass for 20s, coating 20 μ l of solution (B) with 0.84% sodium fluoride aqueous solution by mass for 20s, rinsing with water vapor, and repeating the rinsing with coating solution (A) + solution (B) + for 3 times to keep the surface wet or dry
Example four
The surface topography of the teeth of examples one to three was observed using a field emission scanning electron microscope, and the results are shown in fig. 1. The in-situ deposited nanoparticles are in-situ deposited between and within the dentin collagen fibers, intertwining with the dentin organic matrix.
EXAMPLE five
The distribution of the elements of the fractured surface of the tooth bodies of the first to third embodiments is observed by an energy spectrometer, and the result is shown in fig. 2. Dental organic matrix after treatment with the pretreatment composition of the present invention, the contents of calcium and fluorine elements increase both at the surface and in the interior.
EXAMPLE six
The dental surfaces of examples one to three were characterized using X-ray photoelectron spectroscopy, and the results are shown in fig. 3. Tooth organic substrate surface after treatment with the pretreatment composition of the present invention, the calcium and fluorine elements are increased in surface content.
EXAMPLE seven
The results of the potential measurements on the surfaces of the teeth of examples one to three are shown in FIG. 4. It is shown that the surface potential of the dentin organic matrix increases after in situ deposition of sodium fluoride nanoparticles and gradually increases with increasing deposition of nanoparticles.
Example eight
The quality of the dentin matrix of examples one to three before and after water absorption was measured, and the results are shown in fig. 5. Indicating that the water absorption capacity of the dentin organic matrix is reduced after in situ deposition of sodium fluoride nanoparticles, and the hydration capacity is gradually reduced with the increase of deposited nanoparticles.
Example nine
The specific surface area of the dentin matrixes of examples one to three was measured, and the results are shown in fig. 6. The specific surface area of the dentin organic matrix is increased after in-situ deposition of the sodium fluoride nanoparticles, and the specific surface area is gradually increased along with the increase of the deposited nanoparticles, so that the contact area with the adhesive is greatly increased.
Example ten
The dentin matrices of examples one to three were subjected to nanoindentation test, and the results are shown in fig. 7. The results show that after the sodium fluoride nanoparticles are deposited in situ, the elasticity modulus and hardness of the dentin organic matrix are improved, and gradually increased along with the increase of the deposited nanoparticles, so that the demineralized dentin organic matrix still keeps a fluffy state even under the condition of blow drying.
EXAMPLE eleven
The thickness of the tooth cross section of examples one to three was observed using a field emission scanning electron microscope, and the results are shown in FIG. 8. The dentin organic matrix with nanoparticles deposited in situ did not change significantly in thickness even with blow drying.
Example twelve
Rinsing with water vapor after phosphoric acid etching treatment of the surface of the dentin, keeping the surface wet or drying the surface, coating a Spectrum adhesive or a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
EXAMPLE thirteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet or is dried by blowing, Spectrum adhesive or Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example fourteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out into a cycle, the cycle is repeated for 3 times, the surface is kept wet or is dried by blowing, a Spectrum adhesive or a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the prosthesis.
Example fifteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example sixteen
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.21% barium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.14% sodium sulfate aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example seventeen
In the Spectrum adhesives of the twelve to fourteen examples, 0.01% by mass of nile red dye was mixed, and the samples were cut into 0.1 mm thin pieces perpendicular to the bonding interface along the long axis of dentin by flowing water cooling with a slow cutter, and the bonding interface was observed under a confocal microscope, as shown in FIG. 9. The results show that the dentin organic matrix has better penetration and more uniform distribution after in-situ deposition of the sodium fluoride nano-particles.
EXAMPLE eighteen
The samples in the twelve to sixteen examples were cut along the direction perpendicular to the bonding interface of the long axis of dentin under the cooling of running water by a slow cutting machine to prepare resin-dentin strip samples with bonding surfaces of 1 mm × 1 mm, and the resin-dentin strip samples were subjected to a micro-tensile test by a micro-tensile tester until the samples broke, and the load measured by the micro-tensile tester when the samples broke was recorded. The interfacial width of the sample was measured and the cross-sectional area micro-tensile strength of the sample was calculated. The results are shown in FIGS. 10, 11 and 12. After the dental bonding pretreatment material is used, the bonding strength at the dentin-resin interface is improved and the durability is enhanced in two adhesive materials, and the strength is still high and the durability is still strong even under the condition of blow drying.
Example nineteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and then illumination curing is carried out to bond the prosthesis. The results are shown in FIG. 12.
Example twenty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, then Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis. The results are shown in FIG. 12.
Example twenty one
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and light curing is carried out to bond the restoration.
Example twenty two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and then illumination curing is carried out to bond the restoration.
Example twenty three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example twenty-four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example twenty-five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and light curing is carried out to carry out prosthesis bonding.
Example twenty-six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.11% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, surface drying is carried out, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and light curing is carried out to Bond the restoration.
Example twenty-seven
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Spectrum adhesive, curing by illumination, and adhering the prosthesis.
Example twenty-eight
And (3) rinsing with water vapor after phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Spectrum adhesive, curing by illumination, and adhering the prosthesis.
Example twenty-nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example thirty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example thirty one
And (2) rinsing with water vapor after phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example thirty-two
And (2) rinsing with water vapor after phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example thirty-three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example thirty-four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example thirty-five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example thirty-six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.84% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example thirty-seven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated on the surface, and then illumination curing is carried out to bond the prosthesis.
Example thirty-eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then a Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example thirty-nine
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 2% of calcium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 1.51% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution, coating a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example forty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example forty one
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and light curing is carried out to Bond the restoration.
Example forty two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 2% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.51% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example forty-three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example forty-four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example forty-five
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of potassium monohydrogen phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the cycle of coating solution (A) + solution (B) + washing is repeated for 3 times, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example forty-six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried by blowing, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example forty-seven
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.20% of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.24% of potassium monohydrogen phosphate aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example forty-eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of potassium monohydrogen phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example forty-nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the cycle of coating solution (A) + solution (B) + washing is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example fifty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried by blowing, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the prosthesis.
Example fifty one
After the dentin surface is treated by phosphoric acid etching, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.24 percent of potassium monohydrogen phosphate aqueous solution for 20s, washing with water vapor, keeping the surface wet, coating 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution, coating a Spectrum adhesive, curing by illumination, and adhering a prosthesis.
Example fifty two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24 percent of monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example fifty three
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated, a Spectrum adhesive is coated, and light curing is carried out to carry out prosthesis adhesion.
Example fifty four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated, a Spectrum adhesive is coated, and light curing is carried out to bond the restoration.
Example fifty five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example fifty six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated, a Single Bond2 adhesive is coated, and then light curing is carried out to carry out prosthesis bonding.
Example fifty seven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.20% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.24% monopotassium phosphate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated, a Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example fifty eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example fifty nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, a Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example sixty
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) and the solution (B) are washed into a cycle, the cycle is repeated for 3 times, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example sixty one
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) and the solution (B) are washed into a cycle, the cycle is repeated for 3 times, the surface is dried, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example sixty-two
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A mass fraction) 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) mass fraction 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and then illumination curing is carried out to carry out prosthesis bonding.
Example sixty-three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example sixty-four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example sixty-five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example sixty-six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25% ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example sixty-seven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example sixty-eight
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with 0.11 percent of calcium chloride aqueous solution for 20s by mass fraction, then coating 20 mul of solution (B) with 0.25 percent of ammonium fluoride aqueous solution for 20s by mass fraction, rinsing with water vapor, repeating the cycle of coating solution (A) + solution (B) + rinsing for 3 times, keeping the surface wet, coating 20 mul of solution (C) with 15 percent of 10-MDP ethanol solution by mass fraction, then coating a Spectrum adhesive, curing by light irradiation, and bonding the restoration.
Example sixty-nine
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.11% of calcium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.25% of ammonium fluoride aqueous solution for 20s, rinsing with water vapor, repeating the cycle of coating solution (A) + solution (B) + rinsing for 3 times, drying the surface by blowing, coating 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution, coating a Spectrum adhesive, curing by illumination, and bonding the restoration.
Example seventy
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25% ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, then Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example seventy one
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25 percent of ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example seventy-two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.11% calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.25% ammonium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and then light curing is carried out to carry out prosthesis bonding.
Example seventy-three
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the dentin surface, coating 20 mul of solution (A) with 0.11 percent of calcium chloride aqueous solution for 20s by mass fraction, then coating 20 mul of solution (B) with 0.25 percent of ammonium fluoride aqueous solution for 20s by mass fraction, rinsing with water vapor, repeating the cycle of coating solution (A) + solution (B) + rinsing for 3 times, drying the surface by blowing, coating 20 mul of solution (C) with 15 percent of 10-MDP ethanol solution by mass fraction, then coating a Single Bond2 adhesive, curing by illumination, and bonding the restoration.
Example seventy-four
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 1.20% of magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
Example seventy-five
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 1.20% of magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, drying the surface by blowing, coating a Spectrum adhesive, and performing illumination curing to bond the restoration.
Example seventy-six
After the phosphoric acid etching treatment of the dentin surface, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.84% sodium fluoride aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, wherein the surface is kept wet, coating a Spectrum adhesive, and curing by illumination to bond the prosthesis.
Example seventy-seven
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.84% wt sodium fluoride aqueous solution for 20s, washing with water vapor, repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, drying the surface, coating a Spectrum adhesive, curing by illumination, and adhering the prosthesis.
Example seventy-eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.84% sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example seventy nine
And (3) rinsing with water vapor after the phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with mass fraction of 1.20% magnesium sulfate aqueous solution for 20s, then coating 20 mul of solution (B) with mass fraction of 0.84% sodium fluoride aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example eighty
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of solution (A) with mass fraction of 1.20% magnesium sulfate aqueous solution for 20s, then coating 20 mul of solution (B) with mass fraction of 0.84% sodium fluoride aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, keeping the surface wet, coating Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example eighty one
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the dentin surface, coating 20 mul of solution (A) with the mass fraction of 1.20% of magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.84% of sodium fluoride aqueous solution for 20s, rinsing with water vapor, wherein the coating solution (A) + the solution (B) + rinsing is a cycle, repeating the cycle for 3 times, drying the surface, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example eighty two
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
Example eighty three
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Spectrum adhesive, and performing illumination curing to bond the prosthesis.
Example eighty four
After the dentin surface is treated by phosphoric acid etching, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, wherein the surface is kept wet, coating a Spectrum adhesive, and curing by illumination to bond a restoration.
Example eighty-five
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution for 20s, washing with water vapor, repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, drying the surface, coating a Spectrum adhesive, and performing light curing to bond the prosthesis.
Example eighty six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example eighty seven
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with mass fraction of 1.71% barium hydroxide aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example eighty eight
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of solution (A) with mass fraction of 1.20% magnesium sulfate aqueous solution for 20s, then coating 20 mul of solution (B) with mass fraction of 1.71% barium hydroxide aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, keeping the surface wet, coating Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example eighty nine
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of solution (A) with the mass fraction of 1.20% magnesium sulfate aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 1.71% barium hydroxide aqueous solution for 20s, washing with water vapor, repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, drying the surface, coating a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
EXAMPLE ninety
And (3) rinsing with water vapor after the phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.16% of strontium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Spectrum adhesive, curing by illumination, and adhering the restoration.
EXAMPLE ninety one
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.16% of strontium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, rinsing with water vapor, drying the surface by blowing, coating a Spectrum adhesive, and performing illumination curing to bond the restoration.
EXAMPLE ninety two
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of strontium chloride aqueous solution with the mass fraction of 0.16% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, wherein the surface is kept wet, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
EXAMPLES ninety three
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of strontium chloride aqueous solution with the mass fraction of 0.16% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, washing with water vapor, and repeating the processes of coating solution (A) + solution (B) + washing for 3 times, drying the surface by blowing, coating a Spectrum adhesive, and curing by illumination to bond the prosthesis.
Example ninety four
And (3) rinsing with water vapor after the phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.16% of strontium chloride aqueous solution for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, rinsing with water vapor, keeping the surface wet, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example ninety-five
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 0.16 percent of strontium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 0.14 percent of sodium sulfate aqueous solution for 20s, rinsing with water vapor, drying the surface by blowing, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example ninety six
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of strontium chloride aqueous solution with the mass fraction of 0.16% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, keeping the surface wet, coating a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example ninety seven
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of strontium chloride aqueous solution with the mass fraction of 0.16% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, rinsing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + rinsing for 3 times, drying the surface by blowing, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example ninety eight
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of a barium chloride aqueous solution with the mass fraction of 0.21% on the surface for 20s, then coating 20 mul of a solution with the mass fraction of 0.14% of a sodium sulfate aqueous solution with the surface for 20s, rinsing with water vapor, keeping the surface wet, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
Example ninety nine
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of a barium chloride aqueous solution with the mass fraction of 0.21% on the surface for 20s, then coating 20 mul of a sodium sulfate aqueous solution with the mass fraction of 0.14% on the surface of the dentin for 20s, rinsing with water vapor, drying the surface by blowing, coating a Spectrum adhesive, and performing illumination curing to bond the restoration.
Example one hundred
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of barium chloride aqueous solution with the mass fraction of 0.21% on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, keeping the surface wet, coating a Spectrum adhesive, curing by illumination, and adhering a prosthesis.
Example one hundred and one
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of barium chloride aqueous solution with the mass fraction of 0.21% on the surface for 20s, then coating 20 mul of solution with the mass fraction of 0.14% of sodium sulfate aqueous solution with the mass fraction of 0.14% on the surface of the dentin for 20s, washing with water vapor, repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, drying the surface by blowing, coating a Spectrum adhesive, curing by illumination, and bonding the prosthesis.
Example one hundred and two
And (3) rinsing with water vapor after phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of a barium chloride aqueous solution with the mass fraction of 0.21% on the surface for 20s, then coating 20 mul of a sodium sulfate aqueous solution with the mass fraction of 0.14% on the surface of the dentin for 20s, rinsing with water vapor, drying the surface by blowing, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example one hundred and three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of barium chloride aqueous solution with the mass fraction of 0.21% is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the prosthesis.
Example one hundred and four
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of barium chloride aqueous solution with the mass fraction of 0.21% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.14% of sodium sulfate aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, drying the surface by blowing, coating a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example one hundred and fifty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.17 percent of barium hydroxide aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.16 percent of zinc sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred and six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.16% of zinc sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred and seven
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.16% of zinc sulfate aqueous solution for 20s, washing with water vapor, and repeating the cycle of coating solution (A) + solution (B) + washing for 3 times, keeping the surface wet, coating a Spectrum adhesive, curing by illumination, and bonding a restoration.
Example one hundred and eight
After phosphoric acid etching treatment on the surface of the dentin, washing with water vapor, coating 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% of the solution (A) on the surface for 20s, then coating 20 mul of solution (B) with the mass fraction of 0.16% of zinc sulfate aqueous solution for 20s, washing with water vapor, and repeating the processes of coating solution (A) + solution (B) + washing for 3 times, drying the surface by blowing, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
Example one hundred and nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.17 percent of barium hydroxide aqueous solution is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.16 percent of zinc sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred to ten
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% is coated on the surface for 20s, 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.16% is coated on the surface of the dentin, water vapor washing is carried out, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred and eleven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.16% of zinc sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the prosthesis.
Example one hundred and twelve
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of barium hydroxide aqueous solution with the mass fraction of 0.17% is coated on the surface for 20s, 20 mul of solution (B) with the mass fraction of 0.16% of zinc sulfate aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred and thirteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred and fourteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing, surface drying, coating a Spectrum adhesive, and illumination curing is carried out to bond the restoration.
Example one hundred and fifteen
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred sixteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred seventeen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and then illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred and eighteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred and nineteen
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred twenty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example one hundred twenty one
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and then illumination curing is carried out to bond the prosthesis.
Example one hundred twenty-two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated, a Spectrum adhesive is coated, and then illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred twenty three
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated, a Spectrum adhesive is coated, and light curing is carried out to carry out the prosthesis bonding.
Example one hundred twenty four
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated, a Spectrum adhesive is coated, and light curing is carried out to carry out prosthesis bonding.
Example one hundred twenty five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred twenty six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing and surface drying are carried out, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and then illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred twenty seven
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and then light curing is carried out to carry out prosthesis bonding.
Example one hundred twenty eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 0.0001 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 0.00008 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated, a Single Bond2 adhesive is coated, and light curing is carried out to carry out prosthesis bonding.
Example one hundred twenty nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred thirty
And (3) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution for 20s on the surface, then coating 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution for 20s, rinsing with water vapor, drying the surface, coating a Spectrum adhesive, and curing by illumination to bond the restoration.
Example one hundred thirty one
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, a Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example one hundred thirty two hundred
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred and thirty three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis adhesion.
Example one hundred thirty four
And (2) rinsing with water vapor after phosphoric acid etching treatment on the surface of the dentin, coating 20 mul of solution (A) with 42.7 percent of calcium chloride aqueous solution for 20s by mass fraction, then coating 20 mul of solution (B) with 4 percent of sodium fluoride aqueous solution for 20s by mass fraction, rinsing with water vapor, drying the surface by blowing, coating a Single Bond2 adhesive, and curing by illumination to Bond the restoration.
Example one hundred and thirty five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred thirty six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred thirty seven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Spectrum adhesive is coated, and then illumination curing is carried out to bond the restoration.
Example one hundred and thirty eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, then Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred and thirty-nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for 3 times of circulation, the circulation is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and then illumination curing is carried out to bond the prosthesis.
Example one hundred forty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example one hundred and forty one
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with 42.7 percent of calcium chloride aqueous solution for 20s by mass fraction, then coating 20 mul of solution (B) with 4 percent of sodium fluoride aqueous solution for 20s by mass fraction, rinsing with water vapor, keeping the surface wet, coating 20 mul of solution (C) with 15 percent of 10-MDP ethanol solution by mass fraction, coating a Single Bond2 adhesive, and curing by illumination to Bond the prosthesis.
Example one hundred and forty-two
And (2) rinsing with water vapor after the phosphoric acid etching treatment of the surface of the dentin, coating 20 mul of solution (A) with 42.7 percent of calcium chloride aqueous solution for 20s by mass fraction, then coating 20 mul of solution (B) with 4 percent of sodium fluoride aqueous solution for 20s by mass fraction, rinsing with water vapor, drying the surface by blowing, coating 20 mul of solution (C) with 15 percent of 10-MDP ethanol solution by mass fraction, coating a Single Bond2 adhesive, and performing light curing to Bond the prosthesis.
Example one hundred forty-three
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is carried out for 3 times of circulation, the circulation is kept wet, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to carry out prosthesis bonding.
Example one hundred forty four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of solution (A) with the mass fraction of 42.7 percent of calcium chloride aqueous solution is coated on the surface for 20s, then 20 mul of solution (B) with the mass fraction of 4 percent of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is dried, 20 mul of solution (C) with the mass fraction of 15 percent of 10-MDP ethanol solution is coated on the surface, a Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred forty-five
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example one hundred forty-six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Spectrum adhesive is coated, illumination curing is carried out, and prosthesis bonding is carried out.
Example one hundred forty-seven
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% and solution B is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, the surface is kept wet, Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred forty eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% and solution B is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, surface drying is carried out, Spectrum adhesive is coated, light irradiation curing is carried out, and prosthesis bonding is carried out.
Example one hundred and forty-nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, then 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred fifty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred fifty-one
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of 0.54 percent by mass of calcium chloride aqueous solution and 0.79 percent by mass of calcium sulfate aqueous solution is coated on the surface for 20s, 20 mul of mixed solution of 0.84 percent by mass of sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is carried out for 3 times of circulation, the circulation is repeated, the surface is kept wet, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the prosthesis.
Example one hundred and fifty-two
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% and solution B is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, surface drying is carried out, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred and fifty-three
After the phosphoric acid etching treatment of the dentin surface, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, then 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of mixed solution of 10-MDP ethanol solution with the mass fraction of 15% is coated on the surface, Spectrum adhesive is coated on the surface, and then illumination curing is carried out to bond the prosthesis.
Example one hundred fifty-four
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride water solution with the mass fraction of 0.54% and calcium sulfate water solution with the mass fraction of 0.79% is coated on the surface for 20s, then 20 mul of mixed solution of sodium fluoride water solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, 10-MDP ethanol solution with the mass fraction of 15% is coated on the surface of 20 mul of mixed solution of C, Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example one hundred and fifty-five
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of solution (B) with the mass fraction of 0.84% and sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is carried out for one cycle, the cycle is repeated for 3 times, the surface is kept wet, 20 mul of solution (C) with the mass fraction of 15% and 10-MDP ethanol solution is coated, Spectrum adhesive is coated, and illumination curing is carried out to bond the restoration.
Example one hundred fifty six
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of solution (B) with the mass fraction of 0.84% and sodium fluoride aqueous solution is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, surface drying is carried out, 20 mul of solution (C) with the mass fraction of 15% of 10-MDP ethanol solution is coated, Spectrum adhesive is coated, and illumination curing is carried out to bond the prosthesis.
Example one hundred fifty-seven
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, then 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, the surface is kept wet, 20 mul of mixed solution of 10-MDP ethanol solution with the mass fraction of 15% is coated on the surface, Single Bond2 adhesive is coated, and illumination curing is carried out to Bond the restoration.
Example one hundred and fifty-eight
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride water solution with the mass fraction of 0.54% and calcium sulfate water solution with the mass fraction of 0.79% is coated on the surface for 20s, then 20 mul of mixed solution of sodium fluoride water solution with the mass fraction of 0.84% is coated on the surface for 20s, water vapor washing is carried out, surface drying is carried out, 10-MDP ethanol solution with the mass fraction of 15% is coated on the surface of 20 mul of mixed solution of solution (C), Single Bond2 adhesive is coated, light curing is carried out, and prosthesis bonding is carried out.
Example one hundred and fifty-nine
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of 0.54 percent of calcium chloride aqueous solution and 0.79 percent of calcium sulfate aqueous solution in mass fraction is coated on the surface for 20s, 20 mul of solution (B) is coated on the surface for 20s, 0.84 percent of sodium fluoride aqueous solution in mass fraction is coated on the surface for water vapor washing, the coating solution (A) + the solution (B) + washing is carried out for 3 times of circulation, the circulation is repeated, the surface is kept wet, 20 mul of solution (C) is coated on the surface for 10-MDP ethanol solution in mass fraction of 15 percent, Single Bond2 adhesive is coated, and the prosthesis is cured by illumination and then the prosthesis is bonded.
Example one hundred sixty
After phosphoric acid etching treatment on the surface of the dentin, water vapor washing is carried out, 20 mul of mixed solution of calcium chloride aqueous solution with the mass fraction of 0.54% and calcium sulfate aqueous solution with the mass fraction of 0.79% is coated on the surface for 20s, 20 mul of mixed solution of sodium fluoride aqueous solution with the mass fraction of 0.84% and 20 mul of solution (B) is coated on the surface for 20s, water vapor washing is carried out, the coating solution (A) + the solution (B) + washing is a cycle, the cycle is repeated for 3 times, surface drying is carried out, 20 mul of solution (C) is coated on the surface, 10-MDP ethanol solution with the mass fraction of 15% is coated on the surface, Single Bond2 adhesive is coated, illumination curing is carried out, and restoration bonding is carried out.
Claims (11)
1. The application of the dental adhesion pretreatment material in preparing the adhesion pretreatment agent for the demineralized tooth surface in the oral adhesion process is characterized in that the dental adhesion pretreatment agent is used after the clinical acid treatment of the tooth surface and before the adhesive is coated, wherein when the dental adhesion pretreatment material of a binary system is used, a solution (A) is coated, then a solution (B) is coated, and then the adhesive is coated to carry out the tooth adhesion; when the ternary system dental pretreatment bonding material is used, firstly coating the solution (A) and then coating the solution (B), and after water vapor flushing, coating the solution (C) and then coating the bonding agent for bonding the tooth body;
the dental bonding pretreatment material consists of a binary system or a ternary system, wherein the binary system consists of a solution (A) and a solution (B), the ternary system consists of a solution (A), a solution (B) and a solution (C), the solution (A) is a soluble alkaline earth metal salt solution, the solution (B) is a soluble solution which reacts with the solution (A) to generate an alkaline earth metal salt precipitate, and the solution (C) is an organic monomer solution which is chemically chelated with metal ions of the insoluble alkaline earth metal salt precipitate;
the solution (A) is selected from a soluble magnesium salt solution, a calcium salt solution, a strontium salt solution and a barium salt solution with the mass fraction of 0.0001 percent to the saturated concentration, or a mixed solution of 2 or more solutions;
the solution (B) is selected from soluble fluoride, soluble sulfate solution, soluble carbonate solution, soluble silicate solution, soluble phosphate solution, soluble alkali solution with the mass fraction of 0.0001 percent to the saturated concentration, or the mixed solution of 2 or more solutions;
the organic monomer solution of the solution (C) is selected from 0.0001-15% of 10-methacryloyloxydecyl phosphate, 2,4, 6-trimethylphenyl 2- [4- (dihydroxyphosphoric acid) -2-oxetanyl ] acrylate, 2- [4- (dihydroxyphosphoryl) -2-oxetanyl ] ethyl acrylate, n-dodecyl dihydrogen phosphate, 4-methacryloyloxyethyl trimellitic acid, 4-methacryloyloxytrimellitic anhydride and 2-methacryloyloxyethyl phenyl hydrogen phosphate, and the solvent is water, ethanol, acetone or a mixed solution thereof;
and the solution (A), the solution (B) and the solution (C) in the pretreating agent are packaged separately.
2. The use according to claim 1, wherein the soluble magnesium salt solution in the solution (A) is selected from a magnesium chloride aqueous solution, a magnesium sulfate aqueous solution, a magnesium hydrogen carbonate aqueous solution, or a mixture of 2 or more thereof.
3. The use according to claim 1, wherein the soluble calcium salt solution in the solution (A) is selected from the group consisting of an aqueous solution of calcium chloride, an aqueous solution of calcium sulfate, an aqueous solution of calcium hydrogen carbonate, an aqueous solution of calcium nitrate, an aqueous solution of calcium hydroxide, an aqueous solution of calcium gluconate, an aqueous solution of calcium acetate, an aqueous solution of calcium lactate, an aqueous solution of calcium citrate, and a mixture of 2 or more thereof.
4. The use according to claim 1, wherein the soluble strontium salt solution in the solution (A) is selected from the group consisting of strontium chloride aqueous solution, strontium bicarbonate aqueous solution, strontium nitrate aqueous solution, strontium hydroxide aqueous solution, and a mixture of 2 or more thereof.
5. The use according to claim 1, wherein the soluble barium salt in the solution (A) is selected from an aqueous solution of barium chloride, an aqueous solution of barium nitrate, an aqueous solution of barium hydroxide, or a mixture of 2 or more thereof.
6. The use according to claim 1, wherein the soluble fluoride in the solution (B) is selected from aqueous sodium fluoride solution, aqueous potassium fluoride solution, aqueous ammonium fluoride solution, or a mixture of 2 or more thereof.
7. The use according to claim 1, wherein the soluble sulfate solution in the solution (B) is selected from an aqueous solution of sodium sulfate, potassium sulfate, zinc sulfate, ammonium sulfate, or a mixture of 2 or more thereof.
8. The use according to claim 1, wherein the soluble carbonate solution in the solution (B) is selected from an aqueous solution of sodium carbonate, an aqueous solution of potassium carbonate, an aqueous solution of ammonium carbonate, or a mixed solution of 2 or more thereof.
9. The use according to claim 1, wherein the soluble silicate solution in the solution (B) is selected from a soluble silicate, an aqueous sodium silicate solution, an aqueous potassium silicate solution, an aqueous ammonium silicate solution, or a mixture of 2 or more thereof.
10. The use according to claim 1, wherein the soluble phosphate in the solution (B) is selected from soluble phosphates, sodium monohydrogen phosphate aqueous solution, potassium monohydrogen phosphate aqueous solution, sodium dihydrogen phosphate aqueous solution, potassium phosphate, sodium phosphate, ammonium phosphate, or a mixture of 2 or more thereof.
11. The use according to claim 1, wherein the soluble alkali solution in the solution (B) is selected from sodium hydroxide, potassium hydroxide, or a mixture of 2 or more solutions thereof.
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| PCT/CN2021/072127 WO2022088518A1 (en) | 2020-11-02 | 2021-01-15 | Dental bonding pretreatment material and use |
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| CN104398390A (en) * | 2014-11-24 | 2015-03-11 | 浙江大学 | Dentin primary coating-washing primary coating agent and method thereof |
| CN106176250A (en) * | 2016-08-03 | 2016-12-07 | 浙江大学 | Tooth bonding agent system based on hydrophobic bonding new concept |
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| US5276068A (en) * | 1985-03-29 | 1994-01-04 | Jeneric/Pentron, Inc. | Dental resin materials |
| US4719149A (en) * | 1986-02-28 | 1988-01-12 | Minnesota Mining And Manufacturing Company | Method for priming hard tissue |
| US5037639A (en) * | 1989-05-24 | 1991-08-06 | American Dental Association Health Foundation | Methods and compositions for mineralizing calcified tissues |
| CA2549481A1 (en) * | 2003-12-19 | 2005-07-07 | Kuraray Medical Inc. | One-part dental adhesive composition |
| JP5484334B2 (en) * | 2008-07-25 | 2014-05-07 | 株式会社トクヤマデンタル | Dental adhesive composition |
| CN102172334B (en) * | 2011-03-18 | 2013-01-09 | 南京医科大学 | Method for in-vitro induction of remineralization of dentin |
| CN105342863B (en) * | 2015-12-11 | 2018-08-24 | 张凌 | Application of the epigallocatechin gallic acid fat in terms of improving dental resin adhesives reparation |
| CN106890095B (en) * | 2016-12-07 | 2019-11-12 | 中日友好医院 | Dental restorative material and application thereof for promoting dentin remineralization |
| CN107997972B (en) * | 2017-12-04 | 2021-02-05 | 首都医科大学附属北京口腔医院 | Material for in-situ generation of calcium phytate to seal dentinal lumen and application thereof |
| CN111195207A (en) * | 2020-01-19 | 2020-05-26 | 首都医科大学附属北京口腔医院 | Acid etching mineralizer for increasing adhesiveness of dentin |
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| CN104398390A (en) * | 2014-11-24 | 2015-03-11 | 浙江大学 | Dentin primary coating-washing primary coating agent and method thereof |
| CN106176250A (en) * | 2016-08-03 | 2016-12-07 | 浙江大学 | Tooth bonding agent system based on hydrophobic bonding new concept |
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