CN112205432A - Cationic composite disinfectant based on plant antibacterial extract - Google Patents
Cationic composite disinfectant based on plant antibacterial extract Download PDFInfo
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- CN112205432A CN112205432A CN202011032517.0A CN202011032517A CN112205432A CN 112205432 A CN112205432 A CN 112205432A CN 202011032517 A CN202011032517 A CN 202011032517A CN 112205432 A CN112205432 A CN 112205432A
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- 239000000284 extract Substances 0.000 title claims abstract description 71
- 239000000645 desinfectant Substances 0.000 title claims abstract description 36
- 125000002091 cationic group Chemical group 0.000 title claims abstract description 22
- 239000002131 composite material Substances 0.000 title claims abstract description 17
- 230000000844 anti-bacterial effect Effects 0.000 title description 5
- 230000003385 bacteriostatic effect Effects 0.000 claims abstract description 42
- 229960000686 benzalkonium chloride Drugs 0.000 claims abstract description 12
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 claims abstract description 12
- -1 polyhexamethylene guanidine Polymers 0.000 claims abstract description 12
- 239000008367 deionised water Substances 0.000 claims abstract description 8
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000000314 lubricant Substances 0.000 claims abstract description 5
- 241000196324 Embryophyta Species 0.000 claims description 47
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 241000205585 Aquilegia canadensis Species 0.000 claims description 12
- 241000218636 Thuja Species 0.000 claims description 12
- 241000218202 Coptis Species 0.000 claims description 10
- 235000002991 Coptis groenlandica Nutrition 0.000 claims description 10
- 239000006000 Garlic extract Substances 0.000 claims description 10
- 229940069521 aloe extract Drugs 0.000 claims description 10
- 235000020706 garlic extract Nutrition 0.000 claims description 10
- 239000000419 plant extract Substances 0.000 claims description 7
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical group OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 claims description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 3
- 235000008109 Thuja occidentalis Nutrition 0.000 claims description 3
- 238000001035 drying Methods 0.000 claims description 3
- 238000000605 extraction Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 3
- 238000002137 ultrasound extraction Methods 0.000 claims description 3
- 240000002234 Allium sativum Species 0.000 claims description 2
- 241001116389 Aloe Species 0.000 claims description 2
- 241000037740 Coptis chinensis Species 0.000 claims description 2
- 235000011399 aloe vera Nutrition 0.000 claims description 2
- 235000004611 garlic Nutrition 0.000 claims description 2
- 241000894006 Bacteria Species 0.000 abstract description 6
- 241000700605 Viruses Species 0.000 abstract description 3
- 239000000022 bacteriostatic agent Substances 0.000 description 9
- 238000004659 sterilization and disinfection Methods 0.000 description 8
- 239000000047 product Substances 0.000 description 5
- 230000001954 sterilising effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 4
- 241000233866 Fungi Species 0.000 description 3
- 241000222122 Candida albicans Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 229920002413 Polyhexanide Polymers 0.000 description 2
- 241000191967 Staphylococcus aureus Species 0.000 description 2
- 206010052428 Wound Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 239000003899 bactericide agent Substances 0.000 description 2
- 229940095731 candida albicans Drugs 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 206010051548 Burn infection Diseases 0.000 description 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 description 1
- 241000711573 Coronaviridae Species 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004061 bleaching Methods 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000000460 chlorine Substances 0.000 description 1
- 229910052801 chlorine Inorganic materials 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 230000000249 desinfective effect Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- QWPPOHNGKGFGJK-UHFFFAOYSA-N hypochlorous acid Chemical compound ClO QWPPOHNGKGFGJK-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/40—Liliopsida [monocotyledons]
- A01N65/42—Aloeaceae [Aloe family] or Liliaceae [Lily family], e.g. aloe, veratrum, onion, garlic or chives
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/06—Coniferophyta [gymnosperms], e.g. cypress
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
- A01N65/08—Magnoliopsida [dicotyledons]
- A01N65/32—Ranunculaceae [Buttercup family], e.g. hepatica, hydrastis or goldenseal
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pest Control & Pesticides (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a cationic composite disinfectant based on plant bacteriostatic extracts, which is prepared from the following components in percentage by weight: 0.01-0.5% of benzalkonium chloride, 0.01-0.5% of polyhexamethylene guanidine, 0.1-1.5% of plant bacteriostatic extract, 0.1-0.3% of lubricant and the balance of deionized water; the pH regulator regulates the pH to 6.0-7.0. The invention has reliable safety and can more effectively and reliably realize the daily protection of bacteria and viruses.
Description
Technical Field
The invention relates to the technical field of disinfectant production, in particular to a cationic composite disinfectant based on plant bacteriostatic extracts.
Background
Along with the global spread of the epidemic situation of the novel coronavirus (2019-nCoV), public protection on public and personal hygiene is increasingly emphasized, and the disinfectant is used as an epidemic prevention material necessary for public places, households and personal protection, and the safety and effectiveness problems of the disinfectant are also concerned by more people. For the disinfection of space environment and object surface, the disinfectant of hypochlorous acid system is widely used due to its ideal disinfection effect, low price, broad-spectrum and high-efficiency sterilization characteristics, but it has strong oxidizability, corrosivity and bleaching property, and the released free chlorine may cause poisoning of people, so the safety is always a problem.
Benzalkonium chloride is a cationic surfactant, belongs to a non-oxidative disinfectant, has broad-spectrum and efficient sterilization and disinfection effects, and is commonly used for cleaning wounds of mucous membranes, disinfecting wounds and treating burn infection due to the characteristics of safety, reliability and the like. Polyhexamethylene Hydrochloride (PHMB) is a safe and highly effective broad spectrum antimicrobial agent developed by Avecia, uk and is widely used in medical devices, public environments and care line products. The plant bacteriostatic agent is widely applied to the field of traditional Chinese medicine treatment since ancient times as a natural bacteriostatic agent with higher safety performance, and the plant bacteriostatic agent cannot be widely popularized and applied because the internal active ingredients are more complex and the bacteriostatic mechanism of the plant bacteriostatic agent in the current research is not complete.
Disclosure of Invention
The invention aims to provide a cationic composite disinfectant based on plant bacteriostatic extracts, which is reliable in safety and can more effectively and reliably realize daily protection on bacteria and viruses.
The technical scheme adopted by the invention for solving the technical problems is as follows:
a cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.01-0.5% of benzalkonium chloride, 0.01-0.5% of polyhexamethylene guanidine, 0.1-1.5% of plant bacteriostatic extract, 0.1-0.3% of lubricant and the balance of deionized water; the pH regulator regulates the pH to 6.0-7.0.
The chemical bactericide is compounded with specific natural plant bacteriostatic components, so that an obvious synergistic effect is achieved, and compared with the single use effect of the chemical bactericide and the plant bacteriostatic agent, the bacteriostatic effect is remarkably improved, and the safety of the product is further improved.
Considering the influence of the external use of the bacteriostatic disinfectant on the skin, the pH value is preferably controlled to be weakly acidic. Therefore, the pH value of the bacteriostatic disinfectant is controlled to be 6.0-7.0.
Preferably, the plant bacteriostatic extract comprises the following components in percentage by weight: 9 to 12 percent of thuja extract, 9 to 12 percent of aloe extract, 28 to 35 percent of coptis extract, 24 to 28 percent of honeysuckle extract and 18 to 24 percent of garlic extract. The inventor discovers that the specific plant bacteriostatic agent can play a role in synergy by compounding with the artificially synthesized bacteriostatic agent with definite effect, and the bactericidal efficacy and the application range of the bacteriostatic agent are improved.
Preferably, the preparation method of the plant extract comprises the following steps: drying the plant to be extracted at 50 +/-2 ℃ to constant weight, crushing and sieving for later use, mixing 1g of powder with 8-10mL of absolute ethyl alcohol, performing ultrasonic extraction at 60-65 ℃ for 20-30min, centrifuging after extraction is finished, removing precipitate, and collecting the obtained extract to obtain the plant extract; the plant to be extracted is arborvitae, aloe, coptis chinensis, honeysuckle or garlic.
Preferably, the ultrasonic power is 700-.
Preferably, the lubricant is glycerol.
Preferably, the pH regulator is triethanolamine or sodium carbonate.
Preferably, the benzalkonium chloride accounts for 0.05 to 0.25 percent by weight.
Preferably, the polyhexamethylene guanidine is present in an amount of 0.02 to 0.2% by weight.
Preferably, the weight percentage of the plant bacteriostatic extract is 0.5-1%.
The invention has the beneficial effects that: the safety is reliable, and the daily protection of bacteria and viruses can be realized more effectively and reliably.
Detailed Description
The technical solution of the present invention will be further specifically described below by way of specific examples.
In the present invention, the raw materials and equipment used are commercially available or commonly used in the art, unless otherwise specified. The methods in the following examples are conventional in the art unless otherwise specified.
The preparation method of each plant extract comprises the following steps: drying the plant to be extracted at 50 +/-2 ℃ to constant weight, crushing, sieving by a 60-mesh sieve for later use, mixing according to the proportion of adding 8-10mL of absolute ethyl alcohol into 1g of powder, carrying out ultrasonic extraction at 60-65 ℃, carrying out ultrasonic power of 700-900W, extracting for 20-30min, centrifuging for 3-5min at 4000r/min after extraction is finished, removing precipitate, and collecting the obtained extract, namely the plant extract. Arborvitae extract, aloe extract, coptis extract, honeysuckle extract and garlic extract are prepared by the same method.
Example 1:
a cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.01% of benzalkonium chloride, 0.5% of polyhexamethylene guanidine, 0.1% of plant bacteriostatic extract, 0.1% of glycerol and the balance of deionized water; triethanolamine adjusted the pH to 6.0.
The plant bacteriostatic extract comprises the following components in percentage by weight: 9% of thuja extract, 9% of aloe extract, 35% of coptis extract, 24% of honeysuckle extract and 23% of garlic extract.
Example 2:
a cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.5% of benzalkonium chloride, 0.01% of polyhexamethylene guanidine, 1.5% of plant bacteriostatic extract, 0.3% of glycerol and the balance of deionized water; sodium carbonate adjusted the pH to 7.0.
The plant bacteriostatic extract comprises the following components in percentage by weight: 12% of thuja extract, 12% of aloe extract, 28% of coptis extract, 28% of honeysuckle extract and 20% of garlic extract.
Example 3:
a cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.1% of benzalkonium chloride, 0.1% of polyhexamethylene guanidine, 0.8% of plant bacteriostatic extract, 0.25% of glycerol and the balance of deionized water; triethanolamine adjusted the pH to 6.3.
The plant bacteriostatic extract comprises the following components in percentage by weight: 10.4 percent of thuja extract, 10.6 percent of aloe extract, 31.6 percent of coptis extract, 26.4 percent of honeysuckle extract and 21 percent of garlic extract.
The product obtained in this example is designated disinfectant a.
Example 5:
the present embodiment is different from embodiment 3 in that: the plant bacteriostatic extract comprises the following components in percentage by weight: 11.5 percent of thuja extract, 11.5 percent of aloe extract, 33 percent of coptis extract, 26 percent of honeysuckle extract and 18 percent of garlic extract.
Example 6:
the present embodiment is different from embodiment 3 in that: the plant bacteriostatic extract comprises the following components in percentage by weight: 10% of thuja extract, 10% of aloe extract, 29% of coptis extract, 27% of honeysuckle extract and 24% of garlic extract.
Comparative example 1 (no benzalkonium chloride and polyhexamethylene guanidine)
A cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.8% of plant bacteriostatic extract, 0.25% of glycerol and the balance of deionized water; triethanolamine adjusted the pH to 6.3.
The plant bacteriostatic extract comprises the following components in percentage by weight: 10.4 percent of thuja extract, 10.6 percent of aloe extract, 31.6 percent of coptis extract, 26.4 percent of honeysuckle extract and 21 percent of garlic extract.
The product obtained in this example is labeled disinfectant B.
Comparative example 2 (containing no bacteriostatic plant extract)
A cationic composite disinfectant based on plant bacteriostatic extracts is prepared from the following components in percentage by weight: 0.1% of benzalkonium chloride, 0.1% of polyhexamethylene guanidine, 0.25% of glycerol and the balance of deionized water; triethanolamine adjusted the pH to 6.3.
The plant bacteriostatic extract comprises the following components in percentage by weight: 10.4 percent of thuja extract, 10.6 percent of aloe extract, 31.6 percent of coptis extract, 26.4 percent of honeysuckle extract and 21 percent of garlic extract.
The product obtained in this example was labeled disinfectant C.
The results of quantitative killing tests of bacteria and fungi were carried out with reference to 3 disinfectants, i.e., disinfectant A-disinfectant C, prepared by 2.1.1.5.5 and 2.1.1.7.4 disinfectant technical Specifications (2002) of the Ministry of health, and are shown in the table.
Experimental results show that the cationic disinfectant compounded by benzalkonium chloride and PHMB has high sterilization efficiency, wherein the sterilization rate of staphylococcus aureus and escherichia coli can reach more than 99.999 percent, and the sterilization rate of candida albicans can reach more than 99.99 percent. After the cationic disinfectant and the plant bacteriostatic agent are compounded, the sterilization rate of bacteria represented by staphylococcus aureus and escherichia coli and fungi represented by candida albicans is increased by nearly one order of magnitude, and the obvious synergistic effect of the bacteria and the fungi is embodied.
The above-described embodiments are only preferred embodiments of the present invention, and are not intended to limit the present invention in any way, and other variations and modifications may be made without departing from the spirit of the invention as set forth in the claims.
Claims (9)
1. The cationic composite disinfectant based on the plant bacteriostatic extract is characterized by being prepared from the following components in percentage by weight: 0.01-0.5% of benzalkonium chloride, 0.01-0.5% of polyhexamethylene guanidine, 0.1-1.5% of plant bacteriostatic extract, 0.1-0.3% of lubricant and the balance of deionized water; the pH regulator regulates the pH to 6.0-7.0.
2. The cationic composite disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein the plant bacteriostatic extracts comprise the following components in percentage by weight: 9 to 12 percent of thuja extract, 9 to 12 percent of aloe extract, 28 to 35 percent of coptis extract, 24 to 28 percent of honeysuckle extract and 18 to 24 percent of garlic extract.
3. The cationic composite disinfectant based on plant bacteriostatic extracts as claimed in claim 2, wherein the plant extracts are prepared by the following steps: drying the plant to be extracted at 50 +/-2 ℃ to constant weight, crushing and sieving for later use, mixing 1g of powder with 8-10mL of absolute ethyl alcohol, performing ultrasonic extraction at 60-65 ℃ for 20-30min, centrifuging after extraction is finished, removing precipitate, and collecting the obtained extract to obtain the plant extract; the plant to be extracted is arborvitae, aloe, coptis chinensis, honeysuckle or garlic.
4. The cationic composite disinfectant based on plant bacteriostatic extracts as claimed in claim 3, wherein the ultrasonic power is 700-900W.
5. The cationic complex disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein said lubricant is glycerol.
6. The cationic complex disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein said pH regulator is triethanolamine or sodium carbonate.
7. The cationic complex disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein the weight percentage of benzalkonium chloride is 0.05-0.25%.
8. The cationic composite disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein the weight percentage of the polyhexamethylene guanidine is 0.02-0.2%.
9. The cationic composite disinfectant based on plant bacteriostatic extracts as claimed in claim 1, wherein the weight percentage of the plant bacteriostatic extracts is 0.5-1%.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114145293A (en) * | 2021-12-23 | 2022-03-08 | 湖南普泰尔环境股份有限公司 | Composite disinfectant containing natural plant extracts and preparation method thereof |
| CN114946890A (en) * | 2022-06-16 | 2022-08-30 | 卓聪（上海）环保科技发展有限公司 | Biological environment-friendly disinfectant product for efficiently killing new coronavirus and preparation method thereof |
| CN115152804A (en) * | 2022-08-04 | 2022-10-11 | 烟台三生生物科技有限公司 | Artemisinin disinfectant with mite and bacterium removing functions and preparation method thereof |
| CN116035028A (en) * | 2022-12-28 | 2023-05-02 | 上海南椿新材料科技有限公司 | Composite disinfectant doped with nano silver particles, and preparation method and application thereof |
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