CN112168897A - 一种中成药眼药 - Google Patents
一种中成药眼药 Download PDFInfo
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Abstract
本发明公开了一种中成药眼药的配方,涉及中药制剂及其制备方法领域,具体是一种中药制成的眼药。其特征在于:该配方中包括:夜明砂(黑砂星)25‑30份、动物肝脏30‑35份、木耳3‑5份、月下灰10‑15份、枸杞3‑5份、狗肝菜8‑10份。按一定重量比例称取上述原料。原料取自天然物品,绝不添加防腐剂、抗生素、激素等对人体有害的物质,原料来自药食同源,是过去没有出现过的全新中药组合,是治疗与预防眼疾的良药,适用结膜炎、红眼病、砂眼、眼疲劳,白内障等,治疗效果显著,不易复发,使用方便、舒适。
Description
【技术领域】
本发明涉及一种中成药,具体涉及一种眼药的中药配方及其制备方法。
【背景技术】
眼睛是人心灵的窗口,是人们与社会交流的重要器官,可是,随高科技发展,人们的工作、生活越来越多样化,对眼睛的使用却更加频繁,在生活、工作、学习甚至休闲的时候,电子产品无时无刻都接触在人们生活中,这就加重了眼睛的负担,形成现代人们眼睛疾病频发,引起发病原因多种多样,但是长期面对电脑、手机、强光、熬夜是导致眼疾频发最直接的因素之一;再有当人体正气不足时,从而会导致抵抗力薄弱,外加风寒气邪乘虚侵入人体、流窜经络、阻滞于目,形成局部顽固性感染炎症,由于局部血液循环不畅,所以导致久治不愈。医学上把眼疾分为内外障眼病,现在市面有很多针对眼疾的眼药,这些眼药虽然针对症状不同,但是主要成分有几种:防腐剂、激素、抗生素、消炎成分,存在副作用,这些虽然用量不很大时,偶尔使用对眼不会伤害,但是长期使用不但不会缓解疲劳、改善眼疾,反而损伤眼睛,加重病情。
【发明内容】
针对上述技术问题,本发明的目的是提供一种具有活血化瘀、滋润眼部,不断改善眼局部血液循环和风寒气邪侵入,增强免疫力的眼药的纯中药配方,安全可控,性质稳定,是一种无防腐剂、抗生素、激素等对人体有害的物质的药品。
本发明所解决的技术问题采用以下技术方案来实现:一种眼药的中药配方,是由以下原料药物组成的:夜明砂(黑砂星)、动物肝脏、木耳、月下灰、枸杞、狗肝菜6种,经长期不断研究改进,完善配方,按照一定的重量比例称取原料,通过煎煮成汤剂供饮用;也可制成药片服用;汤剂浓缩经真空干燥成晶体,由温暖开水可速溶饮用;研磨成细腻糊状后制成膏剂点入眼角,经提炼可制成针剂供患者注射使用。
其配方中的各味药的重量份数比的有效范围为夜明砂(黑砂星)25-30份、动物肝脏30-35份、木耳3-5份、月下灰10-15份、枸杞3-5份、狗肝菜8-10份:
该配方中各味药的最佳重量份数比为:夜明砂(黑砂星)25份、动物脏33份、木耳4份、月下灰13份、枸杞4份、狗肝菜9份。
本发明中的药物特性、功效:
夜明砂:味辛、微苦,性寒,归肝经,清凉散泄;主要成分:含胆固醇、尿素、尿酸及维生素A等;功效主治:青盲、雀目、目赤肿痛、白晴溢血、内外翳障、清热明目退翳、散瘀消积除疳;形状:长椭圆形颗粒,两端微尖,长5~7毫米,直径约2毫米,表面粗糙,棕褐色或灰棕色,常有破碎者,呈小颗粒状或粉末状;产地:黑龙江、吉林、辽宁、河北、福建、广东、广西、湖南、湖北、四川、山西、甘肃等地。
动物肝脏,猪科动物猪的肝脏:味甘、苦,性温,归肝经;主要成分:每100克猪肝含有:含蛋白质21.3克,脂肪4.5克,碳水化合物1.4克,钙11毫克,磷270毫克,铁25.0毫克,锌5.78毫克,硫胺素0.40毫克,核黄素2.11毫克,尼克酸16.2毫克,抗坏血酸18毫克;功效主治:有补肝、明目、养血、补血、去除毒素、增强人体免疫力等症的功效,治血虚萎黄、夜盲、目赤。产地:各地均有。
木耳:性平、味甘,入胃、大肠二经,以黑木耳为佳。主要成分:铁、钙、磷和维生素B1等;功效主治:能凉血止血、和血养营、益气润肺、滋阴润燥、护肤美容、养胃健脾,能够抗凝血、抗血栓、降血脂,软化血管,使血液流通畅顺。形状:呈不规则块片,多卷缩,表面平滑,黑褐色面较淡,水浸泡后膨胀,色泽转淡,柔润而微透明,表面有滑润的黏液。
月下灰:微苦,性凉;主要成分:碳酸钾和碳;功效主治:具有止血、健胃生津、抗缺氧、增强机体抗病能力及促进蛋白质合成等功效。形状:黑色粉末,无油腻感,无臭。
枸杞:味甘;性平,归肝经、肾经、肺经;主要成分:脂肪、蛋白质、游离氨基酸、牛磺酸、甜菜碱、维生素B1、B2、E、C,特别是类胡萝卜素含量很高;功效主治:滋补肝肾、明目、具有扶正固本、生津补髓、滋阴补肾、益气安神的功效,从而能达到强身健体、延缓衰老的作用。枸杞是一味良药,可以有效地增强各种脏腑功能,改善大脑的功能和对抗自由基,有延缓衰老的作用。
狗肝菜:性凉,味甘、淡;入心、肝、大肠、小肠经;功效主治:肝肾亏虚、头晕目眩、目视不清、养肝、滋肾、润肺、清热解毒、凉血、防治热病斑疹,暑热烦渴,眼结膜炎,咽喉肿痛,疔疮。产地:福建、台湾、广东、广西、河南、东北、河北、山西、陕西、宁夏、甘肃、青海等地。
工艺选取:优先合理可行的煎煮工艺,全部物质有效成分能溶于水,且对湿热性稳定。
(1)材料粒选取:夜明砂经拣净杂质,簸去泥砂,或漂洗后晒干;月下灰用棉布袋装包裹;木耳洗净;狗肝菜切段;选取新鲜动物肝脏切薄片,全部材料不含黏液质与淀粉类物质,不易焦化糊底;
(2)为充分浸提有效成分,先煎药:夜明砂、木耳、月下灰、狗肝菜先浸泡20-30分钟,然后放入动物肝脏一起武火煮开后转文火煎;
(3)浸泡加水量为材料的4-6倍;
(4)后煎药:为避免材料受热时间过长容易分解破坏:要求先煎药煎煮至最后10分钟加入枸杞共煎。
(5)煎煮时间30-50分钟;一般煎煮2次;
(6)第二次煎煮,第二次加入温水量为第一次水量的三分之二,武火煮开后转文火煎煮30分钟,分别滤出滤液,将两次煎煮的滤液合并,取得混合液总量为总加水量的四分之一;
本方案混合煎煮时不产生沉淀反应。
从实验获得:本方案有效成分混合取得对眼睛有益主要元素:硒元素、蛋白质、黄酮、多糖和多酚四氧化三铁、碳黑、碳酸盐、氮、磷、钾、钙、镁、胡萝卜素、甜菜碱、胡萝卜素、玉蜀黍黄素、烟酸、氨基酸等各种微量元素以及脂肪、脂肪酸、多种维生素等成分和能够明目退翳、养肝补血、去毒素、滋补益肾、凉血止血、软化血管、扶正固本、使病灶获得修复,视力自然得到恢复。
【具体实施方式】
按实施例1中配方1、2、3制备得到的眼药水。
家兔雌雄各15只,将眼药水0.1ml滴入右眼结膜囊中,使得上、下眼脸被动闭合1s,另一测眼睛做自身对照,滴入受实物后1h、24h、48h、72h及第4天和7天,观察受实物眼刺激反应情况,并按眼损害的评分标准记录眼被刺激反的积分
配方类别 | 所用剂量 | 动物数量 | 角膜1 | 虹膜 | 充血 | 积分 |
1 | 0.1ml | 10 | 0 | 0 | 0 | 0 |
2 | 0.1ml | 10 | () | 0 | 0 | 0 |
3 | 0.1ml | 10 | 0 | 0 | 0 | () |
实验结果:动物眼部未出现刺激性症状,其结果表明该眼药水对眼无刺激性。
为了使本发明实现的技术手段、创作特征、达到目的与功效容易明白了解,下面结合具体实施例,进一步阐述本发明。
检验参照《保健食品功能学评价程序和检验方法》
药品
按照实施例1制备得到的眼药汤剂服用。
实施例一
一种中成药眼药,是由以下重量份数的原料组成:夜明砂(黑砂星)25份、动物肝脏33份、木耳3份、月下灰10份、枸杞3份、狗肝菜8份。
将取好的6种原料,按照一定的重量比例称取,通过煎煮成制成眼药汤剂、口服液、药片、蜡丸,汤剂浓缩经真空干燥成晶体,由温暖开水可速溶饮用,制成药膏可外敷用,经提炼可制成针剂供患者注射使用。
本发明的有益效果。
与现有技术相比,本发明提供的一种中成药眼药,原材料取自天然动植物,所配原料药食同源,不会使人产生药物依賴性。为实施挖掘中药,此中成药通过改善人体的内环境提高人体抵抗疾病的能力,顺其自然治好疾病。
病例1
刘某,男,70岁,中山市人,眼睛红肿、疼痛、眼晶体浑浊、视力模糊,持续多年治疗,效果不明显,且症状反复,用此药两周后得以康复,至今20多年保持良好。
病例2
林某,女,76岁,梧州市人,眼睛疼痛、迎风流泪、结膜充血,在此之前连续数年在医院多次治疗没有好转,用此药三周得以治愈。
病例3
王某,男,30岁,中山市人,眼睛红肿、疼痛,结膜充血,症状多年无改善,用此药两周得到痊愈。
病例4
李某,男,8岁,中山市人,眼角膜充血,痛痒不止,发病十多天,医院治疗没有好转,服用此药一周后得以治愈。
人们遇眼疾时,数以百计的患者服用此方剂,都获得康复。
以上显示和描述了本发明的基本原理和主要特征以及本发明的优点。本行业的技术人员应该了解,本发明不受上述实施例的限制,上述实施例和说明书中描述的仅为本发明的优选例,并不用来限制本发明,在不脱离本发明精神和范围的前提下,本发明还会有各种变化和改进,这些变化和改进都落入要求保护的本发明范围内。本发明要求保护范围由所附的权利要求书及其等效物界定。
Claims (3)
1.一种中成药眼药,其特征在于,是由以下重量份数的原料组成:夜明砂(黑砂星)25-30份、动物肝脏30-35份、木耳3-5份、月下灰10-15份、枸杞3-5份、狗肝菜8-10份。
2.一种中成药眼药,其特征在于,是由以下重量份数的原料组成:夜明砂(黑砂星)25份、动物肝脏33份、木耳4份、月下灰13份、枸杞4份、狗肝菜9份。
3.一种中成药眼药,其特征在于,是由原料组成提取液体,制成眼药汤剂、口服液、药片、蜡丸,汤剂浓缩经真空干燥成晶体,由温暖开水可速溶饮用,制成药膏可外敷用,经提炼可制成针剂供患者注射使用。
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