CN112057670A - Liquid dressing for wound - Google Patents
Liquid dressing for wound Download PDFInfo
- Publication number
- CN112057670A CN112057670A CN202011064848.2A CN202011064848A CN112057670A CN 112057670 A CN112057670 A CN 112057670A CN 202011064848 A CN202011064848 A CN 202011064848A CN 112057670 A CN112057670 A CN 112057670A
- Authority
- CN
- China
- Prior art keywords
- wound
- oil
- lubricant
- preservative
- percent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007788 liquid Substances 0.000 title claims abstract description 24
- 239000000314 lubricant Substances 0.000 claims abstract description 26
- 239000003921 oil Substances 0.000 claims abstract description 26
- 239000003755 preservative agent Substances 0.000 claims abstract description 26
- 230000002335 preservative effect Effects 0.000 claims abstract description 26
- 235000009024 Ceanothus sanguineus Nutrition 0.000 claims abstract description 22
- 240000003553 Leptospermum scoparium Species 0.000 claims abstract description 22
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 22
- 239000000341 volatile oil Substances 0.000 claims abstract description 22
- 239000004372 Polyvinyl alcohol Substances 0.000 claims abstract description 21
- 229920002385 Sodium hyaluronate Polymers 0.000 claims abstract description 21
- 229920002451 polyvinyl alcohol Polymers 0.000 claims abstract description 21
- 229940010747 sodium hyaluronate Drugs 0.000 claims abstract description 21
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims abstract description 21
- 229920000642 polymer Polymers 0.000 claims abstract description 19
- 239000011159 matrix material Substances 0.000 claims abstract description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- 239000004519 grease Substances 0.000 claims abstract 2
- 239000004359 castor oil Substances 0.000 claims description 12
- 235000019438 castor oil Nutrition 0.000 claims description 12
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 claims description 12
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 6
- 239000012530 fluid Substances 0.000 claims 5
- 208000027418 Wounds and injury Diseases 0.000 abstract description 34
- 206010052428 Wound Diseases 0.000 abstract description 33
- 230000006378 damage Effects 0.000 abstract description 4
- 241000894006 Bacteria Species 0.000 abstract description 2
- 206010011409 Cross infection Diseases 0.000 abstract description 2
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 2
- 241000700605 Viruses Species 0.000 abstract description 2
- 206010048038 Wound infection Diseases 0.000 abstract description 2
- 244000052616 bacterial pathogen Species 0.000 abstract description 2
- 230000000474 nursing effect Effects 0.000 abstract description 2
- 230000001681 protective effect Effects 0.000 abstract description 2
- 238000005299 abrasion Methods 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- QQGISFDJEJMKIL-JAIQZWGSSA-N (5z)-5-[[3-(hydroxymethyl)thiophen-2-yl]methylidene]-10-methoxy-2,2,4-trimethyl-1h-chromeno[3,4-f]quinolin-9-ol Chemical compound C1=CC=2NC(C)(C)C=C(C)C=2C2=C1C=1C(OC)=C(O)C=CC=1O\C2=C/C=1SC=CC=1CO QQGISFDJEJMKIL-JAIQZWGSSA-N 0.000 description 1
- 208000034656 Contusions Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000010410 layer Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to the technical field of wound liquid dressing, in particular to a wound liquid dressing which comprises liquid grease prepared by taking polymer oil as an effective component and water as a matrix, wherein the effective content of the polymer oil is between 10 and 25 percent, the polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, lubricant and preservative, the natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 30 to 40 percent of the natural tea tree essential oil, 30 to 40 percent of the sodium hyaluronate, 10 to 20 percent of the polyvinyl alcohol, 5 to 10 percent of the lubricant and 2 to 5 percent of the preservative according to mass fraction, the wound liquid dressing can form a layer of protective film on a wound to prevent bacteria and viruses from invading the wound surface and prevent the wound infection, and can effectively cut off the cross infection of pathogenic bacteria among various parts of a human body, all the components are not absorbed by human body, so that it can not cause secondary damage to human body, and is suitable for nursing superficial wound surface and peripheral skin of small wound, abrasion, cut wound, etc.
Description
Technical Field
The invention relates to the technical field of wound liquid dressings, in particular to a wound liquid dressing.
Background
In the life process of an individual, the individual is easy to suffer from the injury of superficial wound surfaces such as scratch, cut wound and the like, and if the individual is not treated in time, the infection, suppuration and even more serious consequences of the skin are easily caused, so the individual needs to be treated in time after the skin is injured, and after the wound is cleaned and disinfected, the individual is sprayed with a liquid dressing which plays a role in physical barrier isolation by forming a protective layer on the wound surface. The wound is protected from infection or deterioration, and the components contained in the wound have no pharmacological effect, are not absorbed by human body, and do not cause secondary damage to human body.
Disclosure of Invention
The invention aims to solve the defect that secondary wound occurs during the traditional gauze and absorbent cotton wound treatment in the prior art, and provides a wound liquid dressing.
In order to achieve the purpose, the invention adopts the following technical scheme:
a liquid dressing for wound is designed, which comprises liquid oil prepared from macromolecular oil as an effective component and water as a matrix.
Preferably, the effective content of the polymer oil is 10-25%.
Preferably, the polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant and a preservative.
Preferably, the natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 30-40% of the natural tea tree essential oil, 30-40% of the sodium hyaluronate, 10-20% of the polyvinyl alcohol, 5-10% of the lubricant and 2-5% of the preservative in percentage by mass.
Preferably, the lubricant is castor oil or hydrogenated castor oil.
Preferably, the preservative is otinib hydrochloride.
The invention provides a wound liquid dressing, which has the beneficial effects that: the natural tea tree essential oil, the sodium hyaluronate and the polyvinyl alcohol are used as main liquid dressings, the dressing can immediately cover and seal wounds after being smeared on the wounds, a layer of protective film is formed on the wounds, bacteria and viruses are prevented from invading the wounds, wound infection is prevented, cross infection of pathogenic bacteria among all parts of human bodies can be effectively cut off, the contained components have no pharmacological effect, all the components are not absorbed by the human bodies, secondary damage can not be caused to the human bodies, and the dressing is suitable for nursing of superficial wounds such as small wounds, bruises and cut wounds and surrounding skin.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Example one
A wound liquid dressing comprises liquid oil prepared from polymer oil as effective component and water as matrix.
The effective content of the polymer oil is 10 percent.
The polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant and a preservative.
The natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 30% of the natural tea tree essential oil, 30% of the sodium hyaluronate, 10% of the polyvinyl alcohol, 5% of the lubricant and 2% of the preservative in percentage by mass.
The lubricant is castor oil or hydrogenated castor oil.
The preservative is otinib hydrochloride.
Example two
A wound liquid dressing comprises liquid oil prepared from polymer oil as effective component and water as matrix.
The effective content of the polymer oil is 15%.
The polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant and a preservative.
The natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 32% of the natural tea tree essential oil, 32% of the sodium hyaluronate, 12% of the polyvinyl alcohol, 6% of the lubricant and 3% of the preservative in percentage by mass.
The lubricant is castor oil or hydrogenated castor oil.
The preservative is otinib hydrochloride.
EXAMPLE III
A wound liquid dressing comprises liquid oil prepared from polymer oil as effective component and water as matrix.
The effective content of the polymer oil is 20%.
The polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant and a preservative.
The natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 34% of the natural tea tree essential oil, 34% of the sodium hyaluronate, 14% of the polyvinyl alcohol, 7% of the lubricant and 4% of the preservative in percentage by mass.
The lubricant is castor oil or hydrogenated castor oil.
The preservative is otinib hydrochloride.
Example four
A wound liquid dressing comprises liquid oil prepared from polymer oil as effective component and water as matrix.
The effective content of the polymer oil is 25 percent.
The polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant and a preservative.
The natural tea tree essential oil, the sodium hyaluronate, the polyvinyl alcohol, the lubricant and the preservative are 38% of the natural tea tree essential oil, 38% of the sodium hyaluronate, 18% of the polyvinyl alcohol, 8% of the lubricant and 5% of the preservative in percentage by mass.
The lubricant is castor oil or hydrogenated castor oil.
The preservative is otinib hydrochloride.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any person skilled in the art should be considered to be within the technical scope of the present invention, and the technical solutions and the inventive concepts thereof according to the present invention should be equivalent or changed within the scope of the present invention.
Claims (6)
1. A wound liquid dressing is characterized by comprising liquid grease which is prepared by taking polymer oil as an effective component and water as a matrix.
2. The wound fluid dressing of claim 1, wherein the effective amount of polymeric oil is between 10-25%.
3. The wound fluid dressing of claim 2, wherein the polymer oil comprises natural tea tree essential oil, sodium hyaluronate, polyvinyl alcohol, a lubricant, and a preservative.
4. The wound fluid dressing of claim 1, wherein the natural tea tree essential oil sodium hyaluronate, polyvinyl alcohol, lubricant and preservative are 30-40% by mass, 10-20% by mass, 5-10% by mass and 2-5% by mass of natural tea tree essential oil.
5. The wound fluid dressing of claim 1, wherein the lubricant is castor oil or hydrogenated castor oil.
6. The wound fluid dressing of claim 1, wherein the preservative is otinib hydrochloride.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011064848.2A CN112057670A (en) | 2020-09-30 | 2020-09-30 | Liquid dressing for wound |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202011064848.2A CN112057670A (en) | 2020-09-30 | 2020-09-30 | Liquid dressing for wound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN112057670A true CN112057670A (en) | 2020-12-11 |
Family
ID=73683270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202011064848.2A Pending CN112057670A (en) | 2020-09-30 | 2020-09-30 | Liquid dressing for wound |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN112057670A (en) |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010018559A2 (en) * | 2008-08-11 | 2010-02-18 | Bk Pharma Systems Ltd. | Formulations for a two-phase management of wound healing and dressings incorporating such formulations. |
| CN104307032A (en) * | 2014-11-05 | 2015-01-28 | 天津工业大学 | Liquid dressing capable of stopping pain and bleeding, resisting bacteria and promoting wound healing |
| CN107137760A (en) * | 2017-05-27 | 2017-09-08 | 河南汇博医疗股份有限公司 | A kind of moisturizing maintenance dressing and preparation method thereof |
| CN107670099A (en) * | 2017-11-28 | 2018-02-09 | 苏州汇涵医用科技发展有限公司 | A kind of liquid dressing and preparation method thereof |
| WO2020051640A1 (en) * | 2018-09-14 | 2020-03-19 | Cocky Smart Pty Ltd | Compositions and methods for enhancing wound healing |
| CN111084902A (en) * | 2019-12-17 | 2020-05-01 | 成都博创必成生物技术有限公司 | Liquid dressing and preparation method thereof |
| CN111166932A (en) * | 2020-02-29 | 2020-05-19 | 海南妙音春制药有限公司 | Liquid wound spray dressing and preparation method thereof |
-
2020
- 2020-09-30 CN CN202011064848.2A patent/CN112057670A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010018559A2 (en) * | 2008-08-11 | 2010-02-18 | Bk Pharma Systems Ltd. | Formulations for a two-phase management of wound healing and dressings incorporating such formulations. |
| CN104307032A (en) * | 2014-11-05 | 2015-01-28 | 天津工业大学 | Liquid dressing capable of stopping pain and bleeding, resisting bacteria and promoting wound healing |
| CN107137760A (en) * | 2017-05-27 | 2017-09-08 | 河南汇博医疗股份有限公司 | A kind of moisturizing maintenance dressing and preparation method thereof |
| CN107670099A (en) * | 2017-11-28 | 2018-02-09 | 苏州汇涵医用科技发展有限公司 | A kind of liquid dressing and preparation method thereof |
| WO2020051640A1 (en) * | 2018-09-14 | 2020-03-19 | Cocky Smart Pty Ltd | Compositions and methods for enhancing wound healing |
| CN111084902A (en) * | 2019-12-17 | 2020-05-01 | 成都博创必成生物技术有限公司 | Liquid dressing and preparation method thereof |
| CN111166932A (en) * | 2020-02-29 | 2020-05-19 | 海南妙音春制药有限公司 | Liquid wound spray dressing and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 沈建忠等译: "《Plumb"s兽药手册》", 31 July 2009, 中国农业大学出版社 * |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201211 |