CN112014584A - Drains and Sample Analyzers - Google Patents

Abstract

The application discloses a liquid discharge device, which is used for sucking liquid in a reaction container and comprises a placing bin, a lifting mechanism, a liquid suction needle with a needle head and a moving part, wherein the placing bin is used for placing the reaction container, the liquid suction needle is fixed on the lifting mechanism and can extend into the reaction container placed in the placing bin along with the descending of the lifting mechanism, so as to suck the liquid in the reaction container by establishing negative pressure, the movable part is movably connected with the lifting mechanism and can be abutted against the reaction container placed in the placing bin along with the descending of the lifting mechanism, wherein, the movable part is structured in such a way that when the needle head of the liquid suction needle moves to a first preset distance away from the bottom of the reaction container placed in the placing bin along with the movement of the lifting mechanism, the downward pressure applied to the reaction container by the movable piece is larger than the suction force applied to the reaction container by the liquid suction needle due to the establishment of negative pressure. The liquid discharge device can better separate the liquid suction needle from the reaction container.

Description

Drains and Sample Analyzers

technical field

The present application relates to the field of medical equipment, and in particular, to a liquid discharge device and a sample analyzer.

Background technique

In chemiluminescence analyzers and other in vitro diagnostic products, in order to facilitate the operator to pick up and place waste and ensure biological safety, there is a waste liquid discharge process when the test is completed, which is used for the solid-liquid separation of the reaction cup and waste liquid. separation.

In order to realize the solid-liquid separation of the reaction cup and the waste liquid, the existing solution is to insert the waste liquid needle into the waste liquid of the reaction cup and establish a negative pressure to suck the waste liquid. In order to ensure that the waste liquid is basically drained and there is no obvious residue, the distance between the waste liquid needle port and the bottom of the reaction cup is very small, and there is a possibility that the needle and the bottom of the reaction cup are completely offset. That is to say, the waste liquid needle may suck the cuvette and lift the cuvette along with it during the movement. At this time, the waste cup cannot be grasped by the cup grasper, and there is a risk that the normal test process will be interrupted and cannot be carried out. If the lifted cuvette falls off, the undrained waste liquid in the cuvette will overturn and cause contamination, which may affect other normal test results.

SUMMARY OF THE INVENTION

Embodiments of the present application provide a liquid discharge device and a sample analyzer.

On the one hand, an embodiment of the present application provides a liquid draining device for sucking liquid in a reaction vessel, including a placement chamber, a lifting mechanism, a liquid aspiration needle with a needle, and a movable part, and the placement chamber is used for placing The reaction container, the suction needle is fixed on the lifting mechanism and the suction needle can be inserted into the reaction container placed in the placing chamber with the descending of the lifting mechanism, so as to establish a negative pressure to The liquid in the reaction container is sucked, the movable member is movably connected with the lifting mechanism, and the movable member can abut on the reaction container placed in the placing bin as the lifting mechanism descends , wherein the movable member is configured to, when the needle of the liquid aspiration needle moves to a first preset distance from the bottom of the reaction container placed in the placement chamber along with the movement of the lifting mechanism, The downward pressure exerted by the movable part on the reaction container is greater than the suction force exerted by the suction needle on the reaction container due to the establishment of negative pressure.

On the other hand, an embodiment of the present application also provides a sample analyzer, including a detection device for detecting a sample in a reaction container and a liquid discharge device for discharging waste liquid in the reaction container after detection.

The liquid draining device provided in the embodiment of the present application is movably connected with the lifting mechanism through a movable member, and the movable member can abut on the reaction container placed in the placing bin as the lifting mechanism descends, so that When the needle of the pipetting needle moves to a first preset distance from the bottom of the reaction container placed in the placing chamber along with the movement of the lifting mechanism, the movable member applies pressure to the reaction container. The downward pressure is greater than the suction force exerted by the suction needle on the reaction vessel due to the establishment of negative pressure, that is, the reaction vessel will not be sucked by the suction needle but taken away by the suction needle, thereby providing a A liquid draining device that can better separate the pipetting needle and the reaction vessel.

Description of drawings

In order to illustrate the technical solutions of the present application more clearly, the following briefly introduces the accompanying drawings used in the implementation manner. Obviously, the accompanying drawings in the following description are only some implementations of the present application, which are common in the art. As far as technical personnel are concerned, other drawings can also be obtained based on these drawings without the need for creative labor.

1 is a schematic three-dimensional structure diagram of a liquid drainage device provided in an embodiment of the present application;

2 is a schematic diagram of the force of the reaction vessel when the liquid discharge device provided in the embodiment of the present application is in a liquid pumping state;

Figure 3 is a schematic top view of the liquid discharge device in Figure 1;

Fig. 4 is the sectional schematic diagram of the liquid discharge device in Fig. 2 along the line I-I;

Fig. 5 is the sectional schematic diagram of the liquid discharge device in Fig. 2 along II-II line;

Fig. 6 is the perspective structure schematic diagram of the liquid discharge device in Fig. 1 from another perspective;

FIG. 7 is a schematic diagram similar to FIG. 4 of another liquid draining device provided in an embodiment of the present application;

Fig. 8 is the schematic diagram that the liquid discharging device in Fig. 4 is in the liquid pumping state;

FIG. 9 is a schematic diagram similar to FIG. 8 of another liquid discharge device provided in an embodiment of the present application;

FIG. 10 is a schematic diagram similar to FIG. 8 of another liquid draining device provided in an embodiment of the present application;

FIG. 11 is a schematic diagram similar to FIG. 8 of another liquid draining device provided in an embodiment of the present application;

FIG. 12 is a schematic diagram similar to FIG. 8 of another liquid draining device provided in an embodiment of the present application;

FIG. 13 is a schematic structural diagram of a sample analyzer provided in an embodiment of the present application.

Detailed ways

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present application.

The serial numbers themselves, such as "first", "second", etc., for the components herein are only used to distinguish the described objects, and do not have any order or technical meaning. The "connection" and "connection" mentioned in this application, unless otherwise specified, include both direct and indirect connections (connections). In the description of this application, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", The orientation or positional relationship indicated by "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present application and simplifying the description , rather than indicating or implying that the referred device or element must have a particular orientation, be constructed and operate in a particular orientation, and therefore should not be construed as a limitation on the present application.

In this application, unless otherwise expressly stated and defined, a first feature "on" or "under" a second feature may be in direct contact with the first and second features, or indirectly through an intermediary between the first and second features touch. Also, the first feature being "above", "over" and "above" the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is level higher than the second feature. The first feature being "below", "below" and "below" the second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature has a lower level than the second feature.

Please refer to FIG. 1 . FIG. 1 is a schematic three-dimensional structure diagram of a liquid draining device 100 according to an embodiment of the present application. The liquid draining device 100 is used for pumping the liquid in the reaction vessel 200 , such as waste liquid. The liquid discharging device 100 includes a placing bin 1 , a lifting mechanism 2 , a liquid suction needle 3 and a movable member 4 . The working process of the liquid discharging device 100 is as follows: place the reaction container 200 that has completed the detection and needs to be sucked into the storage chamber 1, and drive the lifting mechanism 2 to make the suction needle 3 extend into the reaction container 200, so as to remove the reaction vessel 200. The liquid in the container 200 is suctioned. After the suction of the liquid in the reaction container 200 is completed, the lifting mechanism 2 is driven to make the liquid suction needle 3 leave the reaction container 200 .

In order to facilitate the understanding of the various working states of the liquid discharge device 100 provided in the embodiments of the present application, each working state of the liquid discharge device 100 is described in detail here: please refer to FIG. The mechanism 2 drives the liquid suction needle 3 to descend the first preset stroke. At this time, the final distance between the liquid suction needle 3 and the reaction container 200 can be the first preset distance L1; the suction state of the liquid discharge device 100 can be liquid suction The state in which the needle 3 is sucking the liquid in the reaction container 200; the rising state of the liquid discharge device 100 may be a state in which the lifting mechanism 2 drives the suction needle 3 to ascend the second preset stroke, wherein the suction needle 3 finally leaves the reaction container 200. Optionally, when the liquid discharging device 100 is in a suction state, the lifting mechanism 2 may stop moving at this time. When the liquid discharging device 100 is in a rising state, the liquid discharging device 100 may stop suction at this time.

In the embodiment shown in FIG. 1 , the placement chamber 1 is used to place the reaction vessel 200 . For example, the placement chamber 1 may be provided with a blind hole, and the shape of the blind hole matches the shape of the reaction vessel 200 to facilitate the placement of the reaction vessel 200 . After the reaction vessel 200 is placed on the placement chamber 1 , the nozzle of the reaction vessel 200 protrudes from the placement chamber 1 . The liquid suction needle 3 is fixed on the lifting mechanism 2 and the liquid suction needle 3 can extend into the reaction container 200 placed in the placing chamber 1 with the descending of the lifting mechanism 2, so as to suction the liquid in the reaction container 200 by establishing a negative pressure. liquid. Specifically, when the liquid discharging device 100 is in a suction state, the liquid suction needle 3 may exert a suction force F1 on the bottom of the reaction vessel 200 , as shown in FIG. 2 .

In addition, the movable member 4 is movably connected with the lifting mechanism 2 and the movable member 4 can abut on the reaction container 200 placed in the storage bin 1 as the lifting mechanism 2 descends, wherein the movable member 4 is configured so that when the liquid is absorbed When the needle head of the needle 3 moves to the first preset distance L1 from the bottom of the reaction container 200 placed in the placing chamber 1 along with the movement of the lifting mechanism 2, the downward pressure F2 exerted by the movable member 4 on the reaction container 200 is greater than the suction force F2. The suction force F1 exerted by the liquid needle 3 on the reaction vessel 200 due to the establishment of negative pressure. In addition, at this time, the reaction vessel 200 may adhere to the needle port due to the viscous force caused by the sticky substance on the needle tip of the aspiration needle 3. Therefore, the downward pressure F2 should be designed to be larger than the suction force F1 by a certain amount. threshold to ensure that the pipetting needle 3 and the reaction vessel 200 can be separated more reliably.

Specifically, when the liquid discharging device 100 is in the suction state, the force of the reaction container 200 is shown in FIG. A downforce F2. Wherein, when the needle of the aspiration needle 3 moves to the first preset distance L1 from the bottom of the reaction container 200 placed in the placement chamber 1 along with the movement of the lifting mechanism 2, the downward pressure F2 on the reaction container 200 is greater than The reaction container 200 is subjected to the suction force F1, so the reaction container 200 can be pushed into the placement chamber 1 and maintain a first preset distance L1 from the needle of the suction needle 3 in the suction state. When the suction needle 3 is in the rising state after suction, the liquid suction needle 3 can be separated from the reaction container 200, in other words, the reaction container 200 will not be sucked by the liquid suction needle 3 but be taken away by the liquid suction needle 3, so as to provide an The liquid draining device 100 in which the suction needle 3 and the reaction vessel 200 are preferably separated.

Specifically, as shown in FIGS. 3 and 4 , the lifting mechanism 2 can move along the first direction Y to drive the aspiration needle 3 to extend into or leave the reaction container 200 . It can be understood that the first direction Y may be a vertical direction. The lifting mechanism 2 includes a lifting seat 21, the lifting seat 21 has a first end surface 211 (ie a lower end surface) facing the storage bin 1 and a second end surface 212 (ie an upper end surface) opposite to the first end surface 211. The first end surface A groove 211 a for accommodating the movable member 4 is recessed on the 211 , and a first through hole 212 a connected to the groove 211 a is formed on the second end surface 212 , so that the suction needle 3 can pass through and be fixed on the lifting base 21 .

It can be understood that, as shown in FIG. 5 , the lift seat 21 also has a third end surface 213 (ie, a side surface) adjacent to the first end surface 211 and the second end surface 212 , and the third end surface 213 is provided with a through hole connected to the first end surface. In the third through hole 213a of 212a, when the suction needle 3 needs to be fixed on the lifting seat 21, the needle of the suction needle 3 can be passed through the first through hole 212a and the groove 211a of the second end face 212 in sequence until The needle is located in the external environment, and then the set screw 213b is driven into the third through hole 213a of the third end face 213 until the set screw 213b abuts the outer wall of the suction needle 3, thereby fixing the suction needle 3 on the lifting seat 21 , so that the pipetting needle 3 can correspondingly extend into the reaction container 200 or be separated from the reaction container 200 along with the movement of the lifting seat 21 along the first direction Y. Of course, in other embodiments, glue can also be applied between the suction needle 3 and the lifting seat 21 to achieve their fixation.

It can be understood that, as shown in FIG. 6 , the lifting mechanism 2 further includes a mounting plate 22 and a vertical driving mechanism 23. The mounting plate 22 has a first mounting portion 221 and a second mounting portion 222 adjacent to each other. The first mounting portion 221 and the second mounting portion 222 are perpendicular to each other. The vertical drive mechanism 23 includes a motor 231, a timing belt 232 and a connecting assembly 233. The motor 231 is fixed on the first mounting portion 221, and the motor shaft 231a of the motor 231 passes through the first mounting portion 221. One end of the timing belt 232 is sleeved On the motor shaft 231a of the motor 231, the other end of the timing belt 232 is sleeved on the support seat of the first mounting portion 221, and the support seat and the motor shaft 231a are spaced along the first direction Y along the first direction Y. When the motor shaft 231a of the motor 231 rotates, the motor shaft 231a drives the timing belt 232 to rotate, so that the timing belt 232 is driven along the first direction Y. The connecting assembly 233 includes a guide rail 2331 and a connecting piece 2332. The guide rail 2331 is fixed on the second mounting portion 222, one end of the connecting piece 2332 is fixed on the synchronous belt 232, and is movably connected to the guide rail 2331, and the other end of the connecting piece 2332 is fixed. Connected to the second end face 212 of the lift seat 21, so that when the timing belt 232 is driven along the first direction Y, the connecting piece 2332 slides along the guide rail 2331 to drive the lift seat 21 to move along the first direction Y, so that the The aspiration needle 3 extends into the reaction vessel 200 or is separated from the reaction vessel 200 . The lifting mechanism 2 can stably drive the suction needle 3 to move along the first direction Y through the above structure, and the movement precision is high. Of course, in other embodiments, other lifting mechanisms 2 may also be set to drive the suction needle 3 to move, such as a drive mechanism such as a gear column and the like to drive the suction needle 3 to move along the first direction Y.

In one embodiment, as shown in FIG. 4 , the lifting mechanism 2 further includes a baffle plate 24 . The baffle plate 24 is fixedly connected to the first end face 211 to close the groove 211 a , and the second end face 212 is provided with a connection to the groove 211 a . The baffle plate 24 is provided with the first through hole 212a, and the baffle plate 24 is provided with a second through hole 24a that communicates with the groove 211a, so that the suction needle 3 can pass through the second through hole 24a and extend into the reaction vessel placed in the placement chamber 1. 200, and the reaction container 200 can pass through the second through hole 24a and keep in contact with the movable member 4. Specifically, the diameter of the second through hole 24a on the baffle plate 24 is smaller than the diameter of the groove 211a and larger than the diameter of the reaction vessel 200. In this way, when the liquid drain device 100 is in the suction state, the reaction vessel 200 can pass through the hole. The second through hole 24a is in contact with the movable member 4 .

When the movable member 4 needs to be installed in the lifting base 21 , the movable member 4 is inserted through the opening of the groove 211 a , and then the baffle 24 is detachably connected to the first end surface 211 of the lifting base 21 through screws. The movable member 4 can be supported on the baffle plate 24, and the movable member 4 can slide relative to the lifting base 21 along the first direction Y in the groove 211a. The way in which the movable member 4 is supported on the lifting base 21 can support the movable member 4 on the lifting base 21 through simple assembly, thereby reducing the processing cost of the lifting base 21 .

In another embodiment, as shown in FIG. 7 , a slideway 211b is provided on the peripheral surface of the groove 211a, and the movable member 4 is supported in the slideway 211b in the groove 211a and can move along the slideway 211b. Optionally, the movable member 4 includes a sliding block 41 and a pressing member 42 . Specifically, a slideway 211b is recessed on the peripheral surface of the groove 211a of the lift base 21 , and the lengthwise extending direction of the slideway 211b is the first direction Y. The slideway 211b has a stop wall 211d, and the movable member 4 can be supported on the stop wall 211d. The movable member 4 is supported on the lifting base 21 only by processing the lifting base 21 of the corresponding structure, and there is no need to install with other components to support the movable member 4 , thereby reducing the assembly cost of the lifting mechanism 2 .

It can be understood that in the descending state, the magnitude of the downward force F2 can be changed correspondingly with the descending of the lifting mechanism 2 .

In one embodiment, as shown in FIG. 8 , the movable member 4 includes a sliding block 41 and a lower pressing member 42 , the sliding block 41 can be movably accommodated in the groove 211 a of the lifting mechanism 2 , and the lower pressing member 42 has two opposite sides. One end of the lower pressing member 42 is fixedly connected with the lifting mechanism 2 , and the other end of the lower pressing member 42 is fixedly connected with the slider 41 and can be abutted on the placement through the slider 41 as the lifting mechanism 2 descends. On the reaction vessel 200 placed in the chamber 1 , the lower pressure F2 includes the pressure generated by the lower pressing member 42 and the gravity of the slider 41 . Specifically, the slider 41 may be provided with a fourth through hole 41a, and the fourth through hole 41a is for the liquid aspiration needle 3 to pass through. One end of the sliding block 41 can abut on the baffle plate 24 , and the lower pressing member 42 is located between the sliding block 41 and the second end surface 212 of the lifting seat 21 . Optionally, the other end of the slider 41 can be provided with a recessed portion 41b, and the recessed portion 41b can be used for accommodating the pressing member 42, so as to facilitate the fixing of the pressing member 42 on the slider 41. Of course, in other embodiments, the slider 41 can also avoid the liquid aspiration needle 3 , in other words, the liquid aspiration needle 3 does not pass through the slider 41 . Of course, in other embodiments, the other end of the sliding block 41 may also be a flat surface, in other words, the other end of the sliding block 41 may not have the concave portion 41b.

As shown in FIG. 8 , when the liquid discharging device 100 is in the descending state, the lifting seat 21 of the lifting mechanism 2 drives the suction needle 3 to gradually approach the reaction vessel 200 , wherein the slider 41 in the lifting seat 21 gradually approaches the reaction vessel 200 until it contacts the reaction vessel 200 . The reaction vessel 200 is pushed upward by the reaction vessel 200 and slides relative to the lift seat 21 , and the lower pressing member 42 will be applied by the lower pressing member 42 due to the gradual reduction of the distance between the slider 41 and the second end surface 212 of the lifting seat 21 . The pressure on the slider 41 gradually increases. When the needle is separated from the bottom of the reaction vessel 200 by the first preset distance L1, for example, when the liquid draining device 100 is in the critical value of the liquid pumping state, the pressure generated by the lower pressing member 42 is the same as the slider. The gravity of 41 is greater than the suction force F1 exerted by the suction needle 3 of the reaction vessel 200 on the reaction vessel 200, so that the reaction vessel 200 can be pressed down even after being subjected to the suction force F1 of the suction needle 3 on the reaction vessel 200. In the chamber 1 , the pipetting needle 3 can be separated from the reaction vessel 200 .

In this embodiment, the combination of the slider 41 and the lower pressing member 42 enables the sliding block 41 to drive the lower pressing member 42 to move upward along the first direction Y, and the slider 41 can ensure that during the process of pressing the lower pressing member 42 There is always smooth movement, further improving the reliability of the drainage device 100 . In addition, the combination of the gravity of the slider 41 and the pressure of the lower pressing member 42 forms the lower pressure F2, which better ensures that the force exerted by the movable member 4 on the reaction vessel 200 can be greater than the suction force F1 received by the reaction vessel 200, and further ensures the suction The liquid needle 3 and the reaction vessel 200 can be separated more reliably. In addition, in this embodiment, the slider 41 can close the opening of the reaction container 200 to prevent the liquid in the reaction container 200 from flowing out.

Optionally, as shown in FIG. 8 , the lower pressing member 42 may be configured as an elastic member having an opposite first connecting end 421 and a second connecting end 422 , and the first connecting end 421 of the elastic member is fixed to the lifting mechanism 2 connected, and the second connecting end 422 of the elastic member is fixedly connected with the slider 41 and can abut on the reaction vessel 200 placed in the storage chamber 1 through the slider 41 as the lifting mechanism 2 descends, press down The pressure generated by the member 42 includes the elastic force generated by the elastic member being compressed through the sliding block 41 abutting on the reaction vessel 200 placed in the storage chamber 1 as the lifting mechanism 2 descends. It can be understood that the elastic member is preferably configured as a coil spring sleeved on the suction needle 3 . In other words, the aspiration needle 3 passes through the first through hole 212 a , the inner cavity of the coil spring, the fourth through hole 41 a and the second through hole 24 a in sequence until the needle head is located outside the lifting seat 21 . The coil spring is sleeved on the liquid suction needle 3, so that the liquid suction needle 3 guides the elastic deformation direction of the screw spring, so as to ensure that the coil spring can generate pressure along the first direction Y during the elastic deformation process. The portion of the coil spring at the second connection end 422 can be located in the recessed portion 41b. Of course, in other embodiments, the elastic member may comprise a plurality of springs arranged around the pipetting needle 3 . In other words, the suction needle 3 passes through the second through hole 24a, the inner cavity enclosed by a plurality of springs, the fourth through hole 41a and the first through hole 212a in sequence until the needle head is located outside the lifting seat 21 . The lower pressing member 42 formed by a combination of multiple springs provides greater pressure.

Optionally, as shown in FIG. 9 , the pressing member 42 may include a first magnetic member 423 and a second magnetic member 424 disposed opposite to each other, and the first magnetic member 423 and the second magnetic member 424 are arranged such that the first magnetic member 423 Contrary to the magnetism of the opposite pole ends of the second magnetic member 424 , the first magnetic member 423 is fixed on the lifting mechanism 2 , and the second magnetic member 424 is fixedly connected with the slider 41 and can be lowered with the lifting mechanism 2 . When the slider 41 abuts on the reaction vessel 200 placed in the storage chamber 1 , the pressure generated by the pressing member 42 includes the magnetic repulsion force of the first magnetic member 423 and the second magnetic member 424 . Specifically, the first magnetic member 423 and the second magnetic member 424 can be electromagnets, which can change their own magnetism by controlling the direction of the current. The arrangement of the magnetic poles of the first magnetic member 423 and the second magnetic member 434 may be as follows: the opposite magnetic poles of the first magnetic member 423 and the second magnetic member 434 are both S-poles or N-poles. The magnetic poles of 423 and the second magnetic member 434 opposite to each other repel each other. The first magnetic member 423 is fixed on the lift base 21 , and the second magnetic member 424 is located in the recessed portion 41 b of the slider 41 . Optionally, the first magnetic member 423 and the second magnetic member 424 may be respectively provided with through holes for allowing the liquid aspiration needle 3 to pass through. The smaller the distance between the first magnetic member 423 and the second magnetic member 424, the greater the magnetic repulsion force. Of course, in other embodiments, the first magnetic member 423 and the second magnetic member 424 may also be disposed away from the liquid aspiration needle 3 .

In another embodiment, as shown in FIG. 10, the movable member 4 may only have an elastic member 43 without a slider. One end of the elastic member 43 is fixed on the lifting mechanism 2, and the other end of the elastic member 43 can follow the lifting mechanism. 2 descends to abut against the reaction vessel 200 placed in the placement chamber 1, and the downward force F2 includes the elastic member 43 being compressed against the reaction vessel 200 placed in the placement chamber 1 as the lifting mechanism 2 descends. resulting elastic force.

The structure of the elastic member 43 shown in FIG. 10 may be the same as that of the elastic member shown in FIG. 8 , the main difference is that the other end of the elastic member 43 can directly contact the reaction vessel 200 . In other words, when the liquid discharging device 100 is in the descending state, the lifting seat 21 of the lifting mechanism 2 drives the suction needle 3 to gradually approach the reaction vessel 200, wherein the other end of the elastic member 43 in the lifting seat 21 will gradually approach the reaction vessel 200 until it contacts the reaction vessel 200. The container 200 is elastically deformed by the reaction container 200, and the elastic member 43 gradually increases the pressure of the elastic member 43 on the slider 41 as the amount of elastic deformation gradually increases. When the needle and the bottom of the reaction container 200 The first preset distance L1, for example, when the liquid discharging device 100 is in the critical value of the liquid suction state, the pressure generated by the lower pressing member 42 is greater than the suction force F1 exerted by the liquid suction needle 3 on the reaction vessel 200, so that the reaction vessel 200 Even after receiving the suction force F1 of the liquid pipetting needle 3 to the reaction container 200 , it can be pressed down in the placing chamber 1 , so that the liquid pipetting needle 3 can be separated from the reaction container 200 .

In yet another embodiment, as shown in FIG. 11 , the movable member 4 may only include a first magnetic member 44 and a second magnetic member 45 arranged opposite to each other, and the first magnetic member 44 and the second magnetic member 45 are arranged such that the first magnetic member 44 and the second magnetic member The magnetism of the opposite pole ends of the magnetic member 44 and the second magnetic member 45 is opposite, the first magnetic member 44 is fixed on the lifting mechanism 2, the second magnetic member 45 is slidably connected to the lifting mechanism 2, and the second magnetic member 45 can abut against the reaction container 200 placed in the storage bin 1 as the lifting mechanism 2 descends, and the lowering force F2 includes the magnetic repulsion force of the first magnetic member 44 and the second magnetic member 45 .

The structures of the first magnetic member 44 and the second magnetic member 45 shown in FIG. 11 may be the same as the structures of the first magnetic member 423 and the second magnetic member 424 shown in FIG. The member 45 directly abuts on the baffle plate 24 or is supported in the chute 211b, and can slide relative to the lift seat 21 along the first direction Y. In other words, when the liquid draining device 100 is in the descending state, the lifting seat 21 of the lifting mechanism 2 drives the suction needle 3 to gradually approach the reaction vessel 200, wherein the second magnetic member 45 in the lifting seat 21 will gradually approach the reaction vessel 200 until it contacts the reaction vessel 200 and is pushed upward by the reaction vessel 200 to gradually approach the first magnetic member 44, and as the distance between the second magnetic member 45 and the first magnetic member 44 gradually decreases, the pressure exerted by the second magnetic member 45 on the reaction vessel 200 Gradually increase, when the needle and the bottom of the reaction vessel 200 are separated from the first preset distance L1, that is, when the liquid discharging device 100 is in the critical value of the liquid pumping state, the magnetic force generated by the first magnetic member 44 and the second magnetic member 45 is greater than the suction liquid. The suction force F1 exerted by the needle 3 on the reaction vessel 200 enables the reaction vessel 200 to be pressed down in the placement chamber 1 even when subjected to the suction force F1 of the suction needle 3, so that the suction needle 3 can interact with the suction needle 3. The reaction vessel 200 is phase separated.

It can be understood that in the suction state, the magnitude of the downward pressure F2 may remain unchanged. Specifically, as shown in FIG. 12 , the movable member 4 only has the slider 46 , the slider 46 can be movably accommodated in the groove 211 a of the lifting mechanism 2 , and the downward force F2 only includes the gravity of the slider 41 . Specifically, the structure of the sliding block 46 may be the same as that of the sliding block 41 shown in FIG. 8 , and details are not described herein again.

Specifically, when the liquid discharge device 100 is in the descending state, the lifting seat 21 of the lifting mechanism 2 drives the suction needle 3 to gradually approach the reaction container 200 , wherein the slider 41 in the lifting seat 21 gradually approaches the reaction container 200 until it contacts the reaction container 200 and is pushed upward by the reaction container 200. During this process, the gravity applied by the slider 41 to the reaction container 200 remains unchanged. In other words, the gravity is always greater than the first preset distance L1 between the needle and the bottom of the reaction container 200. When the liquid device 100 is at the critical value of the liquid suction state, the suction force F1 exerted by the liquid suction needle 3 on the reaction vessel 200, so that the reaction vessel 200 can still be pressed down even when it is subjected to the suction force F1 of the liquid suction needle 3. The chamber 1 is placed so that the pipetting needle 3 can be separated from the reaction vessel 200 .

Further, the liquid discharging device 100 further includes a sliding bearing, and the sliding bearing is arranged on the movable part of the movable member 4 relative to the lifting mechanism 2 . Specifically, the specific setting of the sliding bearing is based on the setting of the part of the movable member 4 that is specifically movable relative to the lifting mechanism 2 . For example, when the movable part of the movable member 4 relative to the lifting mechanism 2 is the sliding block 41 , the sliding bearing is disposed between the sliding block 41 and the lifting seat 21 to facilitate the sliding of the sliding block 41 in the lifting seat 21 . When the movable part of the movable member 4 relative to the lifting mechanism 2 is the elastic member or the second magnetic member 424 , the sliding bearing is correspondingly arranged, which will not be repeated here.

Further, the liquid discharging device 100 further includes a controller and a suction pump electrically connected to the controller, the suction pump is connected to the suction needle 3, and the controller is configured to: when the needle of the suction needle 3 follows the lifting mechanism 2 When the needle descends to reach the reaction vessel 200 placed in the placement chamber 1 and the needle has a first preset distance L1 from the bottom of the reaction vessel 200, the suction pump is controlled to establish a negative pressure to suck the liquid in the reaction vessel 200 . It can be understood that after the liquid in the reaction vessel 200 is sucked, the controller further controls the suction pump to stop working, and at the same time the controller controls the motor to drive the lifting mechanism 2 to rise to separate the suction needle 3 from the reaction vessel 200 .

When the liquid discharge device 100 of the embodiment of the present application performs liquid suction, it will be introduced by taking FIG. 8 as an example. First, the lifting mechanism 2 of the liquid discharge device 100 is driven to descend along the first direction Y. In this descending state, the lifting seat 21 will Gradually approach the reaction vessel 200 until the reaction vessel 200 abuts on the slider 41 , the slider 41 will slide upward along the first direction Y due to the abutment of the reaction vessel 200 and gradually shrink to the second end face of the lift seat 21 212, the elastic member will be squeezed and elastically deformed as the sliding block 41 slides, and the pressure applied to the sliding block 41 by the elastic member will gradually increase with the gradual increase of the elastic deformation amount. When the lifting mechanism 2 descends to the maximum distance, that is, when the needle tip of the suction needle 3 of the liquid discharging device 100 descends to the first preset distance L1 from the bottom of the reaction vessel 200, the pressing member 42 is applied to the pressure of the reaction vessel 200. The pressure and the gravity applied by the slider 41 to the reaction vessel 200 are greater than the suction force F1 applied by the suction needle 3 to the reaction vessel 200 ; then the suction pump is controlled to work so that the suction needle 3 creates a negative pressure to pump the reaction vessel 200 Suck. Wherein, since the pressure applied by the elastic member to the reaction container 200 and the gravity applied by the slider 41 to the reaction container 200 are greater than the suction force F1 applied by the suction needle 3 to the reaction container 200 , the reaction container 200 is always pressed by the movable member 4 on the reaction container 200 . placed in the chamber 1 without being sucked by the suction needle 3; finally, after the liquid in the reaction container 200 is sucked, the controller further controls the suction pump to stop working, and at the same time, the controller drives the lifting mechanism 2 to rise to The pipetting needle 3 is separated from the reaction vessel 200 .

The liquid draining device 100 provided in the embodiment of the present application is movably connected with the lifting mechanism 2 through the movable member 4, and the movable member 4 can abut on the reaction container 200 placed in the storage chamber 1 as the lifting mechanism 2 descends, so that when When the needle descends to the first preset distance L1 from the bottom of the reaction vessel 200 placed in the placement chamber 1 with the descending of the lifting mechanism 2 , the downward pressure F2 exerted by the movable member 4 on the reaction vessel 200 is greater than that of the suction needle 3 The suction force F1 applied to the reaction container 200 due to the establishment of the negative pressure, that is, the reaction container 200 will not be sucked by the liquid suction needle 3 but be taken away by the liquid suction needle 3, thereby providing a suction needle capable of 3. The draining device 100 which is preferably separated from the reaction vessel 200.

The embodiment of the present application further provides a sample analyzer 1000, including a detection device for detecting a sample in the reaction container 200 and a liquid discharge device 100 for discharging the waste liquid in the reaction container 200 after detection.

It can be understood that the sample analyzer 1000, especially the chemiluminescence immunoassay analyzer, is used to analyze and detect the sample to be tested, so as to obtain corresponding detection results and meet the usage requirements. It should be noted that the specific type of the sample to be tested is not limited. In some embodiments, the sample to be tested includes a solid sample or a liquid sample. The sample analyzer 1000 includes a sample reagent storage device, the sample reagent storage device includes a sample loading mechanism for loading samples and a reagent loading mechanism for loading reagents, the reagent loading mechanism has a reagent pot for storing reagents and the above-mentioned refrigeration device, The refrigerating device is arranged in the reagent pot and cools the reagent pot, and the support plate of the refrigerating device is arranged on the bottom of the reagent pot. Preferably, the support plate of the refrigeration device is located outside the reagent pot.

Specifically, as shown in FIG. 13 , the sample analyzer 1000 may further include a sample reagent storage device 1001 for loading samples and reagents, a dispensing device 1003 for aspirating and discharging samples and reagents, and a mixing device for supporting the reaction vessel 200 . Shaping (not shown), incubation photometric device 1002 for incubation and luminescence detection, magnetic separation and cleaning device 1004 for separation and cleaning, reaction vessel 200 grabbing device 1005 for transporting reaction vessel 200, and liquid circuit device (not shown).

The sample reagent storage device 1004 includes a sample loading mechanism for loading samples and a reagent loading mechanism for loading reagents. The sample loading mechanism is sleeved outside the reagent loading mechanism, and the sample loading mechanism and the reagent loading mechanism rotate independently of each other.

The grasping device 1005 of the reaction container 200 transfers the reaction container 200 to the mixing seat; the dispensing device 1003 is located above the sample reagent storage device 1001, and can transfer the sample and reagent to the reaction container 200 of the mixing seat respectively; the reaction The container 200 grasping device 1005 transfers the reaction container 200 from the mixing base to the incubation photometric device 1002 for incubation, and the reaction container 200 grasping device 1005 also transfers the incubated reaction container 200 to the magnetic separation and cleaning device 1004 for separation and cleaning, The separated and cleaned reaction vessel 200 is transferred to the incubation photometric device 1002 for luminescence detection.

The liquid circuit device is respectively connected with the dispensing device 1003 and the magnetic separation cleaning device 1004. The liquid circuit device controls the dispensing device 1003 to suck and discharge samples or reagents and clean the dispensing device 1003. The liquid circuit device is also used for injecting or Drain the cleaning fluid.

The sample analyzer provided in the embodiment of the present application is movably connected with the lifting mechanism 2 through the movable member 4, and the movable member 4 can abut on the reaction container 200 placed in the storage chamber 1 as the lifting mechanism 2 descends, so that when the needle When the lifting mechanism 2 descends to the first preset distance L1 from the bottom of the reaction vessel 200 placed in the storage bin 1, the downward pressure F2 exerted by the movable member 4 on the reaction vessel 200 is greater than that of the suction needle 3 due to The suction force F1 exerted on the reaction vessel 200 due to the establishment of negative pressure, that is, the reaction vessel 200 will not be sucked by the suction needle 3 but be taken away by the suction needle 3, thereby providing a suction needle 3 capable of The drain device 100 is preferably separated from the reaction vessel 200 .

The features mentioned above in the description, the claims and the drawings can all be combined with one another arbitrarily as long as they are meaningful within the scope of the present application. The advantages and features described for the drain device 100 apply in a corresponding manner to the sample analyzer 1000 and vice versa.

The above are the preferred embodiments of the present application. It should be pointed out that for those of ordinary skill in the art, some improvements and modifications can be made without departing from the principles of the present application. These improvements and modifications are also regarded as the present invention. The scope of protection applied for.

Claims (17)

1. A liquid discharge device is used for sucking liquid in a reaction container, and is characterized by comprising a placing bin, a lifting mechanism, a liquid suction needle with a needle head and a movable piece, wherein the placing bin is used for placing the reaction container, the liquid suction needle is fixed on the lifting mechanism and can extend into the reaction container placed in the placing bin along with the descending of the lifting mechanism so as to suck the liquid in the reaction container by establishing negative pressure, the movable piece is movably connected with the lifting mechanism and can abut against the reaction container placed in the placing bin along with the descending of the lifting mechanism, the movable piece is structured in a way that when the needle head of the liquid suction needle moves to a first preset distance away from the bottom of the reaction container placed in the placing bin along with the movement of the lifting mechanism, the lower pressure applied to the reaction container by the movable piece is larger than the suction force applied to the reaction container by the liquid suction needle due to the establishment of negative pressure.

2. The liquid discharge device of claim 1, wherein the movable member comprises a slider movably received in the recess of the lifting mechanism, and a lower member having opposite ends, one end of the lower member being fixedly connected to the lifting mechanism, and the other end of the lower member being fixedly connected to the slider and capable of abutting against the reaction vessel placed in the placing chamber through the slider as the lifting mechanism descends, and the lower pressure includes a pressure generated by the lower member and a weight of the slider.

3. The liquid discharge device according to claim 2, wherein the pressing member is configured as an elastic member having a first connecting end and a second connecting end which are opposite to each other, the first connecting end of the elastic member is fixedly connected to the elevating mechanism, and the second connecting end of the elastic member is fixedly connected to the slider and can be abutted by the slider on the reaction vessel placed in the placing chamber as the elevating mechanism descends, and the pressure generated by the pressing member includes an elastic force generated by the elastic member being compressed by the slider on the reaction vessel placed in the placing chamber as the elevating mechanism descends.

4. The drainage device of claim 3, wherein the elastic member is configured as a coil spring sleeved on the pipette needle.

5. The drain of claim 3, wherein the resilient member comprises a plurality of springs disposed about the pipette needle.

6. The drain of claim 2, wherein the press-down member includes a first magnetic member and a second magnetic member disposed opposite to each other, the first magnetic member is fixed to the elevating mechanism, the second magnetic member is fixedly connected to the slider and is capable of abutting against a reaction vessel placed in the placing chamber through the slider as the elevating mechanism descends, and the pressure generated by the press-down member includes a magnetic repulsive force of the first magnetic member and the second magnetic member.

7. The drain of any one of claims 1 to 6, wherein the lifting mechanism comprises a lifting seat and a baffle, the lifting seat is provided with a first end surface facing the placing cabin and a second end surface opposite to the first end surface, the first end surface is concavely provided with a groove for accommodating the movable member, the baffle plate is fixedly connected to the first end surface to close the groove and support the movable member, the second end surface is provided with a first through hole communicated with the groove, so that the liquid suction needle can penetrate through and be fixed on the lifting seat, the baffle plate is provided with a second through hole communicated with the groove, so that the liquid suction needle can penetrate through the second through hole and extend into the reaction container placed in the placing bin, and the reaction container can penetrate through the second through hole and is kept in abutting joint with the movable piece.

8. The drain of any one of claims 2 to 6, wherein a slide is provided on the peripheral surface of the groove, the slide being supported in the groove in the slide and being movable along the slide.

9. The drain of claim 1, wherein the movable member has a slider movably received in a recess of the elevator mechanism, and the downward force comprises only the weight of the slider.

10. The liquid discharge apparatus as claimed in claim 1, wherein the movable member has an elastic member, one end of the elastic member is fixed to the elevating mechanism, the other end of the elastic member is capable of abutting against the reaction vessel placed in the placing chamber as the elevating mechanism descends, and the downward pressure includes an elastic force generated by the elastic member being compressed as the elastic member abuts against the reaction vessel placed in the placing chamber as the elevating mechanism descends.

11. The drain of claim 1, wherein the movable member comprises a first magnetic member and a second magnetic member that are oppositely disposed and magnetically repulsed, the first magnetic member and the second magnetic member are arranged such that the magnetic properties of the magnetic pole ends of the first magnetic member and the second magnetic member are opposite, the first magnetic member is fixed to the lifting mechanism, the second magnetic member is slidably connected to the lifting mechanism, the second magnetic member can abut against the reaction vessel placed in the placing chamber as the lifting mechanism descends, and the downward pressure comprises a magnetic repulsion force of the first magnetic member and the second magnetic member.

12. The drain of any one of claims 9 to 11, the lifting mechanism comprises a lifting seat and a baffle plate, the lifting seat is provided with a first end surface facing the placing bin and a second end surface opposite to the first end surface, the first end surface is concavely provided with a groove for accommodating the moving part, the baffle plate is fixedly connected to the first end surface to close the groove and support the moving part, the second end surface is provided with a first through hole communicated with the groove, so that the liquid suction needle can penetrate through and be fixed on the lifting seat, the baffle plate is provided with a second through hole communicated with the groove, so that the liquid suction needle can penetrate through the second through hole and extend into the reaction container placed in the placing bin, and the reaction container can penetrate through the second through hole and is kept in abutting joint with the movable piece.

13. The drain of claim 9, wherein a slide is provided on a peripheral surface of the groove, the slide being supported in the groove in the slide and movable along the slide.

14. The drain of any one of claims 1 to 13, further comprising a slide bearing disposed on a portion of the movable member that is movable relative to the lift mechanism.

15. The drain of any one of claims 1 to 13, further comprising a controller and a suction pump electrically connected to the controller, the suction pump being connected to the pipette needle, the controller being configured to: when the needle head of the liquid suction needle extends into the reaction container placed in the placing bin along with the descending of the lifting mechanism and the needle head has a first preset distance from the bottom of the reaction container, controlling the suction pump to establish negative pressure so as to suck the liquid in the reaction container.

16. A sample analyzer comprising a detecting means for detecting a sample in a reaction vessel and the liquid discharge means of any one of claims 1 to 15 for discharging a waste liquid in the reaction vessel after detection.

17. The sample analyzer of claim 16 configured as a chemiluminescent immunoassay analyzer.

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