CN111973481A - Blue ketone peptide repair essence and preparation method thereof - Google Patents
Blue ketone peptide repair essence and preparation method thereof Download PDFInfo
- Publication number
- CN111973481A CN111973481A CN201911236702.9A CN201911236702A CN111973481A CN 111973481 A CN111973481 A CN 111973481A CN 201911236702 A CN201911236702 A CN 201911236702A CN 111973481 A CN111973481 A CN 111973481A
- Authority
- CN
- China
- Prior art keywords
- component
- extract
- parts
- components
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 22
- 150000002576 ketones Chemical class 0.000 title claims abstract description 18
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 230000008439 repair process Effects 0.000 title claims description 17
- 239000000284 extract Substances 0.000 claims abstract description 183
- 239000000203 mixture Substances 0.000 claims abstract description 163
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 101
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 55
- 244000075850 Avena orientalis Species 0.000 claims abstract description 52
- 235000007319 Avena orientalis Nutrition 0.000 claims abstract description 52
- 240000000073 Achillea millefolium Species 0.000 claims abstract description 51
- 235000007754 Achillea millefolium Nutrition 0.000 claims abstract description 51
- 240000000249 Morus alba Species 0.000 claims abstract description 51
- 235000008708 Morus alba Nutrition 0.000 claims abstract description 51
- 235000014676 Phragmites communis Nutrition 0.000 claims abstract description 50
- 238000000605 extraction Methods 0.000 claims abstract description 43
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 35
- 240000002853 Nelumbo nucifera Species 0.000 claims abstract description 34
- 235000006508 Nelumbo nucifera Nutrition 0.000 claims abstract description 34
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims abstract description 29
- 108010073771 Soybean Proteins Proteins 0.000 claims abstract description 28
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 28
- 241000199919 Phaeophyceae Species 0.000 claims abstract description 27
- 238000000855 fermentation Methods 0.000 claims abstract description 27
- 230000004151 fermentation Effects 0.000 claims abstract description 27
- 229940001941 soy protein Drugs 0.000 claims abstract description 26
- 241000167854 Bourreria succulenta Species 0.000 claims abstract description 25
- 235000019693 cherries Nutrition 0.000 claims abstract description 25
- 241000186660 Lactobacillus Species 0.000 claims abstract description 22
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 22
- 229940039696 lactobacillus Drugs 0.000 claims abstract description 22
- TXFPEBPIARQUIG-UHFFFAOYSA-N 4'-hydroxyacetophenone Chemical compound CC(=O)C1=CC=C(O)C=C1 TXFPEBPIARQUIG-UHFFFAOYSA-N 0.000 claims abstract description 20
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 17
- 230000009089 cytolysis Effects 0.000 claims abstract description 17
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract description 16
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 15
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 15
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 15
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims abstract description 14
- 229960000458 allantoin Drugs 0.000 claims abstract description 14
- 235000014655 lactic acid Nutrition 0.000 claims abstract description 14
- 239000004310 lactic acid Substances 0.000 claims abstract description 14
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910052802 copper Inorganic materials 0.000 claims abstract description 13
- 239000010949 copper Substances 0.000 claims abstract description 13
- YPFDHNVEDLHUCE-UHFFFAOYSA-N 1,3-propanediol Substances OCCCO YPFDHNVEDLHUCE-UHFFFAOYSA-N 0.000 claims abstract description 11
- 244000303040 Glycyrrhiza glabra Species 0.000 claims abstract description 11
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims abstract description 11
- 229940015975 1,2-hexanediol Drugs 0.000 claims abstract description 10
- AEQDJSLRWYMAQI-UHFFFAOYSA-N 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline Chemical compound C1CN2CC(C(=C(OC)C=C3)OC)=C3CC2C2=C1C=C(OC)C(OC)=C2 AEQDJSLRWYMAQI-UHFFFAOYSA-N 0.000 claims abstract description 10
- 241001530056 Athelia rolfsii Species 0.000 claims abstract description 10
- 241001519524 Kappaphycus alvarezii Species 0.000 claims abstract description 10
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 10
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 10
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000000176 sodium gluconate Substances 0.000 claims abstract description 10
- 235000012207 sodium gluconate Nutrition 0.000 claims abstract description 10
- 229940005574 sodium gluconate Drugs 0.000 claims abstract description 10
- DNIAPMSPPWPWGF-VKHMYHEASA-N (+)-propylene glycol Chemical compound C[C@H](O)CO DNIAPMSPPWPWGF-VKHMYHEASA-N 0.000 claims abstract description 9
- 229940035437 1,3-propanediol Drugs 0.000 claims abstract description 9
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims abstract description 9
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims abstract description 9
- 235000006510 Nelumbo pentapetala Nutrition 0.000 claims abstract description 9
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims abstract description 9
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims abstract description 9
- 229920000166 polytrimethylene carbonate Polymers 0.000 claims abstract description 9
- 238000002156 mixing Methods 0.000 claims description 81
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 45
- 244000197580 Poria cocos Species 0.000 claims description 35
- 235000008599 Poria cocos Nutrition 0.000 claims description 35
- 244000273256 Phragmites communis Species 0.000 claims description 32
- 241000831729 Phyllacantha Species 0.000 claims description 26
- 240000001691 Syzygium luehmannii Species 0.000 claims description 25
- 238000003756 stirring Methods 0.000 claims description 22
- 244000146462 Centella asiatica Species 0.000 claims description 18
- 235000004032 Centella asiatica Nutrition 0.000 claims description 18
- 241000628997 Flos Species 0.000 claims description 18
- 238000001816 cooling Methods 0.000 claims description 16
- 239000011718 vitamin C Substances 0.000 claims description 13
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 11
- 229930003268 Vitamin C Natural products 0.000 claims description 11
- 235000019154 vitamin C Nutrition 0.000 claims description 11
- 244000020551 Helianthus annuus Species 0.000 claims description 10
- 235000003222 Helianthus annuus Nutrition 0.000 claims description 10
- 239000006166 lysate Substances 0.000 claims description 9
- 210000000582 semen Anatomy 0.000 claims description 8
- 241000894006 Bacteria Species 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 5
- 239000000498 cooling water Substances 0.000 claims description 4
- 238000007599 discharging Methods 0.000 claims description 4
- 230000001804 emulsifying effect Effects 0.000 claims description 4
- 239000000839 emulsion Substances 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 238000010438 heat treatment Methods 0.000 claims description 4
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 claims 1
- 239000012141 concentrate Substances 0.000 claims 1
- 230000003301 hydrolyzing effect Effects 0.000 claims 1
- 230000003716 rejuvenation Effects 0.000 claims 1
- 235000020238 sunflower seed Nutrition 0.000 abstract description 2
- OBMZMSLWNNWEJA-XNCRXQDQSA-N C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 Chemical compound C1=CC=2C(C[C@@H]3NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CCN(CCCC[C@H](NC(=O)[C@@H](CC4=CC=CC=C4)NC3=O)C(=O)N)CC=C)NC(=O)[C@@H](N)C)CC3=CNC4=C3C=CC=C4)C)=CNC=2C=C1 OBMZMSLWNNWEJA-XNCRXQDQSA-N 0.000 abstract 1
- 101710176384 Peptide 1 Proteins 0.000 abstract 1
- 229940059958 centella asiatica extract Drugs 0.000 abstract 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 description 82
- 230000000694 effects Effects 0.000 description 28
- JVTAAEKCZFNVCJ-REOHCLBHSA-N L-lactic acid Chemical compound C[C@H](O)C(O)=O JVTAAEKCZFNVCJ-REOHCLBHSA-N 0.000 description 18
- 239000000686 essence Substances 0.000 description 15
- 230000003078 antioxidant effect Effects 0.000 description 14
- 239000002537 cosmetic Substances 0.000 description 14
- 239000000047 product Substances 0.000 description 14
- 230000003020 moisturizing effect Effects 0.000 description 9
- 239000003963 antioxidant agent Substances 0.000 description 8
- 235000006708 antioxidants Nutrition 0.000 description 8
- 239000003906 humectant Substances 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 230000002087 whitening effect Effects 0.000 description 8
- 230000037303 wrinkles Effects 0.000 description 8
- 239000002211 L-ascorbic acid Substances 0.000 description 7
- 235000000069 L-ascorbic acid Nutrition 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 7
- 235000011187 glycerol Nutrition 0.000 description 7
- 102000008186 Collagen Human genes 0.000 description 6
- 108010035532 Collagen Proteins 0.000 description 6
- 230000003110 anti-inflammatory effect Effects 0.000 description 6
- 229920001436 collagen Polymers 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 230000002401 inhibitory effect Effects 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 230000004060 metabolic process Effects 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 230000002335 preservative effect Effects 0.000 description 4
- 210000000434 stratum corneum Anatomy 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 102000003425 Tyrosinase Human genes 0.000 description 3
- 108060008724 Tyrosinase Proteins 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000002738 chelating agent Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000003750 conditioning effect Effects 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 210000002950 fibroblast Anatomy 0.000 description 3
- 150000004676 glycans Chemical class 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 239000000419 plant extract Substances 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 231100000241 scar Toxicity 0.000 description 3
- 210000004927 skin cell Anatomy 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- 229920000832 Cutin Polymers 0.000 description 2
- 229930182843 D-Lactic acid Natural products 0.000 description 2
- JVTAAEKCZFNVCJ-UWTATZPHSA-N D-lactic acid Chemical compound C[C@@H](O)C(O)=O JVTAAEKCZFNVCJ-UWTATZPHSA-N 0.000 description 2
- 102000016942 Elastin Human genes 0.000 description 2
- 108010014258 Elastin Proteins 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 108060001084 Luciferase Proteins 0.000 description 2
- 239000005089 Luciferase Substances 0.000 description 2
- WYQVAPGDARQUBT-FGWHUCSPSA-N Madecassol Chemical compound O([C@@H]1[C@@H](CO)O[C@H]([C@@H]([C@H]1O)O)OC[C@H]1O[C@H]([C@@H]([C@@H](O)[C@@H]1O)O)OC(=O)[C@]12CC[C@H]([C@@H]([C@H]1C=1[C@@]([C@@]3(CC[C@H]4[C@](C)(CO)[C@@H](O)[C@H](O)C[C@]4(C)[C@H]3CC=1)C)(C)CC2)C)C)[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O WYQVAPGDARQUBT-FGWHUCSPSA-N 0.000 description 2
- XUMBMVFBXHLACL-UHFFFAOYSA-N Melanin Chemical compound O=C1C(=O)C(C2=CNC3=C(C(C(=O)C4=C32)=O)C)=C2C4=CNC2=C1C XUMBMVFBXHLACL-UHFFFAOYSA-N 0.000 description 2
- 102000016387 Pancreatic elastase Human genes 0.000 description 2
- 108010067372 Pancreatic elastase Proteins 0.000 description 2
- 229920002385 Sodium hyaluronate Polymers 0.000 description 2
- 150000007513 acids Chemical class 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 229940069521 aloe extract Drugs 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- WYQVAPGDARQUBT-XCWYDTOWSA-N asiaticoside Natural products O=C(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]2[C@H](O)[C@H](O)[C@H](O[C@H]3[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O3)[C@@H](CO)O2)O1)[C@@]12[C@@H]([C@@H](C)[C@H](C)CC1)C=1[C@](C)([C@@]3(C)[C@@H]([C@@]4(C)[C@H]([C@@](CO)(C)[C@@H](O)[C@H](O)C4)CC3)CC=1)CC2 WYQVAPGDARQUBT-XCWYDTOWSA-N 0.000 description 2
- 229940022757 asiaticoside Drugs 0.000 description 2
- QCYLIQBVLZBPNK-UHFFFAOYSA-N asiaticoside A Natural products O1C(C(=O)C(C)C)=CC(C)C(C2(C(OC(C)=O)CC34C5)C)C1CC2(C)C3CCC(C1(C)C)C45CCC1OC1OCC(O)C(O)C1O QCYLIQBVLZBPNK-UHFFFAOYSA-N 0.000 description 2
- 230000003385 bacteriostatic effect Effects 0.000 description 2
- 230000001595 contractor effect Effects 0.000 description 2
- 239000008406 cosmetic ingredient Substances 0.000 description 2
- 229940022769 d- lactic acid Drugs 0.000 description 2
- 238000004042 decolorization Methods 0.000 description 2
- 229920002549 elastin Polymers 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 239000006210 lotion Substances 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 230000014759 maintenance of location Effects 0.000 description 2
- 230000004118 muscle contraction Effects 0.000 description 2
- 235000015097 nutrients Nutrition 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 150000003904 phospholipids Chemical class 0.000 description 2
- 229920005862 polyol Polymers 0.000 description 2
- 150000003077 polyols Chemical class 0.000 description 2
- 230000035755 proliferation Effects 0.000 description 2
- 229940010747 sodium hyaluronate Drugs 0.000 description 2
- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 2
- 235000019710 soybean protein Nutrition 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- 229940088594 vitamin Drugs 0.000 description 2
- 229930003231 vitamin Natural products 0.000 description 2
- 235000013343 vitamin Nutrition 0.000 description 2
- 239000011782 vitamin Substances 0.000 description 2
- AJLNZWYOJAWBCR-OOPVGHQCSA-N (4s)-4-acetamido-5-[[(2s)-1-[[(2s)-1-[[(2s)-5-amino-1-[[(2s)-1-[[(2s)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-car Chemical compound OC(=O)CC[C@H](NC(C)=O)C(=C)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCN=C(N)N)C(N)=O AJLNZWYOJAWBCR-OOPVGHQCSA-N 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-M (E)-Ferulic acid Natural products COC1=CC(\C=C\C([O-])=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-M 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- FEBUJFMRSBAMES-UHFFFAOYSA-N 2-[(2-{[3,5-dihydroxy-2-(hydroxymethyl)-6-phosphanyloxan-4-yl]oxy}-3,5-dihydroxy-6-({[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-4-yl)oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl phosphinite Chemical compound OC1C(O)C(O)C(CO)OC1OCC1C(O)C(OC2C(C(OP)C(O)C(CO)O2)O)C(O)C(OC2C(C(CO)OC(P)C2O)O)O1 FEBUJFMRSBAMES-UHFFFAOYSA-N 0.000 description 1
- ADOHEWVFRZKRHE-UHFFFAOYSA-N 2-acetyloxyethyl(trimethyl)azanium Chemical compound CC(=O)OCC[N+](C)(C)C.CC(=O)OCC[N+](C)(C)C ADOHEWVFRZKRHE-UHFFFAOYSA-N 0.000 description 1
- OSCJHTSDLYVCQC-UHFFFAOYSA-N 2-ethylhexyl 4-[[4-[4-(tert-butylcarbamoyl)anilino]-6-[4-(2-ethylhexoxycarbonyl)anilino]-1,3,5-triazin-2-yl]amino]benzoate Chemical compound C1=CC(C(=O)OCC(CC)CCCC)=CC=C1NC1=NC(NC=2C=CC(=CC=2)C(=O)NC(C)(C)C)=NC(NC=2C=CC(=CC=2)C(=O)OCC(CC)CCCC)=N1 OSCJHTSDLYVCQC-UHFFFAOYSA-N 0.000 description 1
- LXAHHHIGZXPRKQ-UHFFFAOYSA-N 5-fluoro-2-methylpyridine Chemical compound CC1=CC=C(F)C=N1 LXAHHHIGZXPRKQ-UHFFFAOYSA-N 0.000 description 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 description 1
- 208000020154 Acnes Diseases 0.000 description 1
- 241000208327 Apocynaceae Species 0.000 description 1
- 235000008658 Artemisia capillaris Nutrition 0.000 description 1
- 241000092668 Artemisia capillaris Species 0.000 description 1
- 235000003069 Artemisia scoparia Nutrition 0.000 description 1
- 241001249148 Artemisia scoparia Species 0.000 description 1
- 241000208838 Asteraceae Species 0.000 description 1
- 208000035985 Body Odor Diseases 0.000 description 1
- YDNKGFDKKRUKPY-JHOUSYSJSA-N C16 ceramide Natural products CCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@H](O)C=CCCCCCCCCCCCCC YDNKGFDKKRUKPY-JHOUSYSJSA-N 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 239000005749 Copper compound Substances 0.000 description 1
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 1
- AHMIDUVKSGCHAU-UHFFFAOYSA-N Dopaquinone Natural products OC(=O)C(N)CC1=CC(=O)C(=O)C=C1 AHMIDUVKSGCHAU-UHFFFAOYSA-N 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010052804 Drug tolerance Diseases 0.000 description 1
- 206010013786 Dry skin Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 102000009123 Fibrin Human genes 0.000 description 1
- 108010073385 Fibrin Proteins 0.000 description 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 102000053187 Glucuronidase Human genes 0.000 description 1
- 108010060309 Glucuronidase Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- AHMIDUVKSGCHAU-LURJTMIESA-N L-dopaquinone Chemical compound [O-]C(=O)[C@@H]([NH3+])CC1=CC(=O)C(=O)C=C1 AHMIDUVKSGCHAU-LURJTMIESA-N 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 208000003351 Melanosis Diseases 0.000 description 1
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 description 1
- CRJGESKKUOMBCT-VQTJNVASSA-N N-acetylsphinganine Chemical compound CCCCCCCCCCCCCCC[C@@H](O)[C@H](CO)NC(C)=O CRJGESKKUOMBCT-VQTJNVASSA-N 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 108010013639 Peptidoglycan Proteins 0.000 description 1
- 102000003992 Peroxidases Human genes 0.000 description 1
- 108010076504 Protein Sorting Signals Proteins 0.000 description 1
- 241000206572 Rhodophyta Species 0.000 description 1
- 240000000111 Saccharum officinarum Species 0.000 description 1
- 235000007201 Saccharum officinarum Nutrition 0.000 description 1
- 229920002305 Schizophyllan Polymers 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 206010040904 Skin odour abnormal Diseases 0.000 description 1
- 206010072170 Skin wound Diseases 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 229940124532 absorption promoter Drugs 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 229940095094 acetyl hexapeptide-8 Drugs 0.000 description 1
- 108010006338 acetyl-glutamyl-glutamyl-methionyl-glutaminyl-arginyl-argininamide Proteins 0.000 description 1
- 229940105017 achillea millefolium extract Drugs 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000012190 activator Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 210000001789 adipocyte Anatomy 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229940072056 alginate Drugs 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-DVKNGEFBSA-N alpha-D-glucose Chemical group OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-DVKNGEFBSA-N 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 239000003098 androgen Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000003260 anti-sepsis Effects 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 230000001153 anti-wrinkle effect Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 239000002199 base oil Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 229940106189 ceramide Drugs 0.000 description 1
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001880 copper compounds Chemical class 0.000 description 1
- 229910001431 copper ion Inorganic materials 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 239000006071 cream Substances 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 230000035618 desquamation Effects 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 1
- 230000037336 dry skin Effects 0.000 description 1
- 239000003974 emollient agent Substances 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 210000001339 epidermal cell Anatomy 0.000 description 1
- 210000005175 epidermal keratinocyte Anatomy 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 210000003560 epithelium corneal Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000001815 facial effect Effects 0.000 description 1
- 210000001097 facial muscle Anatomy 0.000 description 1
- 238000005562 fading Methods 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- KSEBMYQBYZTDHS-UHFFFAOYSA-N ferulic acid Natural products COC1=CC(C=CC(O)=O)=CC=C1O KSEBMYQBYZTDHS-UHFFFAOYSA-N 0.000 description 1
- KSEBMYQBYZTDHS-HWKANZROSA-N ferulic acid Chemical compound COC1=CC(\C=C\C(O)=O)=CC=C1O KSEBMYQBYZTDHS-HWKANZROSA-N 0.000 description 1
- 229940114124 ferulic acid Drugs 0.000 description 1
- 235000001785 ferulic acid Nutrition 0.000 description 1
- 229950003499 fibrin Drugs 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 150000008195 galaktosides Chemical class 0.000 description 1
- 229940072008 glycyrrhiza glabra extract Drugs 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 230000036074 healthy skin Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 102000006495 integrins Human genes 0.000 description 1
- 108010044426 integrins Proteins 0.000 description 1
- 239000002085 irritant Substances 0.000 description 1
- 231100000021 irritant Toxicity 0.000 description 1
- 235000015110 jellies Nutrition 0.000 description 1
- 239000008274 jelly Substances 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 230000001050 lubricating effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000008099 melanin synthesis Effects 0.000 description 1
- 230000005012 migration Effects 0.000 description 1
- 238000013508 migration Methods 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 108091005601 modified peptides Proteins 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 229920005615 natural polymer Polymers 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- 230000007830 nerve conduction Effects 0.000 description 1
- VVGIYYKRAMHVLU-UHFFFAOYSA-N newbouldiamide Natural products CCCCCCCCCCCCCCCCCCCC(O)C(O)C(O)C(CO)NC(=O)CCCCCCCCCCCCCCCCC VVGIYYKRAMHVLU-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 235000015816 nutrient absorption Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000005022 packaging material Substances 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 108040007629 peroxidase activity proteins Proteins 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000006116 polymerization reaction Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 230000002062 proliferating effect Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- 239000002453 shampoo Substances 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 230000008591 skin barrier function Effects 0.000 description 1
- 239000012748 slip agent Substances 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000007838 tissue remodeling Effects 0.000 description 1
- QURCVMIEKCOAJU-UHFFFAOYSA-N trans-isoferulic acid Natural products COC1=CC=C(C=CC(O)=O)C=C1O QURCVMIEKCOAJU-UHFFFAOYSA-N 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9706—Algae
- A61K8/9717—Rhodophycota or Rhodophyta [red algae], e.g. Porphyra
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Botany (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The invention discloses a blue ketone peptide repairing essence and a preparation method thereof, and the blue ketone peptide repairing essence is characterized by comprising the following components in parts by weight: 70-75 parts of water; 4-6 parts of 1, 3-propanediol; 2-4 parts of butanediol; lactobacillus fermentation lysis mixture 2-4; 2-3 parts of oat kernel extraction mixture; 2-3 parts of brown algae extraction mixture; 2-3 parts of glycerol; 1-2 parts of hydrolyzed soy protein mixture; extracting the mixture of broad-leaved cherry fruit 0.5-1.2; 0.6-1 of mulberry root extraction mixture; 0.4-0.7 of hyaluronic acid; 0.4-0.7 of 1, 2-hexanediol; allantoin 0.4-0.7; 0.3-0.5 of centella asiatica extract; 0.3-0.5 of p-hydroxyacetophenone; 0.3-0.5 of lotus flower extraction mixture; 0.3-0.5 of lactic acid; peptide-1 copper 0.1-0.2; 0.05-0.12 of sunflower seeds; 0.05-0.12 of hydrolyzed sclerotium rolfsii gum; 0.05 to 0.12 percent of sodium gluconate; 0.05-0.12% of the extract mixture of milfoil; 0.04-0.06 of Glycyrrhiza glabra; acetyl hexapeptide-80.04-0.06; 0.04-0.06 of ascorbic acid; kappaphycus alvarezii extract 0.02-0.04; the reed extraction mixture is 0.005-0.011; poria extract mixture 0.005-0.011; pentapeptide-30.005-0.011; disodium EDTA 0.005-0.011.
Description
Technical Field
The invention relates to daily chemical products, in particular to a blue ketone peptide repairing essence and a preparation method thereof.
Background
The essence is one of skin care products for face, contains precious effective components such as plant extract, ceramide, squalane, etc., and has effects of preventing aging, removing wrinkle, keeping moisture, whitening skin, removing macula, etc. The essence is usually applied after the skin lotion, before the lotion or cream. The essence is rich in various functional components and has higher concentration, so the price is generally more expensive than other cosmetics.
But currently, most of the essences with skin conditioning adopt chemicals and even antibiotics. Although this method has a fast and good therapeutic effect, it causes imbalance of skin secretion and causes drug resistance and tolerance, so that its side effects are also great. Particularly, the existing essence products with different shapes and colors cannot be distinguished by consumers due to limited knowledge. Even if the pure plant formula is marked, the pure plant formula also has great side effects due to improper selection and proportion of the components.
Disclosure of Invention
In view of the above defects in the prior art, the technical problem to be solved by the present invention is to provide a repair essence of a cyanohydrin peptide and a preparation method thereof, wherein each component is controlled in an effective range, so that the repair essence can perform the functions of maintenance and conditioning, and can prevent the generation of large side effects.
In order to achieve the purpose, the invention provides a blue ketone peptide repair essence which comprises the following components in parts by weight:
component 1: 70-75 parts of water
And (2) component: 1, 3-propanediol 4-6
And (3) component: butanediol 2-4
And (4) component: lactic acid bacteria fermentation lysis mixture 2-4
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2-3
And (4) component 6: extracting mixture 2-3 of brown algae (PHYLLACANTHA FIBROSA)
And (4) component 7: glycerol 2-3
And (4) component 8: hydrolyzed soy protein mixture 1-2
And (3) component 9: the extract mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) fruit is 0.5-1.2, and the components are 10: 0.6-1 part of extract mixture of root of black mulberry (Morus NIGRA)
The components of (11): hyaluronic acid 0.4-0.7
And (2) component 12: 0.4-0.7% of 1, 2-hexanediol
A component 13: allantoin 0.4-0.7
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.3-0.5
The components of 15: 0.3-0.5 of p-hydroxyacetophenone
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.3-0.5
A component 17: lactic acid 0.3-0.5
The components of 18: tripeptide-1 copper 0.1-0.2
A component 19: semen Helianthi (Helianthus ANNUUS) 0.05-0.12
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.05-0.12
The components of 21: sodium gluconate 0.05-0.12
The components of 22: extract of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) 0.05-0.12
Component 23: 0.04-0.06 of Glycyrrhiza glabra
And (3) component 24: acetyl hexapeptide-80.04-0.06
Component 25: ascorbic acid (vitamin C)0.04-0.06
The component (26): kappaphycus alvarezii extract 0.02-0.04
The components of 27: the extract mixture of rhizoma Phragmitis (PHRAGMITES COMMUNIS) is 0.005-0.011
Component 28: poria (Poria COCOS) extract mixture 0.005-0.011
The component (29): pentapeptide-30.005-0.011
30 parts of a component: 0.005-0.011 of EDTA disodium;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: 68-76 of lactobacillus fermentation lysate and 24-32 of water;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: 85-92 parts of oat (AVENA SATIVA) kernel extract and 8-15 parts of water;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: 45-55 parts of brown algae (PHYLLACANTHA FIBROSA) extract and 45-55 parts of water;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: 38-44 parts of hydrolyzed soy protein and 56-62 parts of water;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: 28-34 parts of small broad-leaved cherry (SYZYGIUM LUEHMANNII) fruit extract, 48-55 parts of water and 11-24 parts of propylene glycol;
The components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: 28-32 parts of black mulberry (MORUS NIGRA) root extract and 68-72 parts of water;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: 38-44% of flos Nelumbinis (Nelumbium SPECIOSUM) extract and 56-62% of water;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: 34-38 parts of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract, 62-66 parts of water;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: 38-44 parts of reed (PHRAGMITES COMMUNIS) extract and 56-62 parts of water;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: 38-44 parts of PORIA COCOS (Poria COCOS) extract and 56-62 parts of water.
The component 1 is used as a solvent for mixing and dissolving the components;
the component 2 is used as a humectant, the 1, 3-propylene glycol source is corn sugar, and the corn propylene glycol is called in the industry, and the component is safe and mild and does not cause phenomena such as irritation and discomfort to skin. Can be used as humectant, thickener and solvent in cosmetic.
Component 3 acts as a humectant and solvent, being a mild polyol which increases product smoothness, is widely used in cosmetic applications and may produce a slight irritation, although there is no evidence of sensitization, and both CIR and FDA have been evaluated as safe. The skin care product is commonly used as a micromolecule moisturizing component, can retain water in the horny layer, has good hygroscopicity, can absorb water which is equivalent to 12.5 percent (relative humidity is 50 percent) and 38.5 percent (relative humidity is 80 percent) of the mass of the skin care product, and also has a certain bacteriostatic action.
Component 4 is used as skin conditioner, the lactobacillus fermentation lysate contains thallus and all active ingredients synthesized in the fermentation process, contains peptidoglycan, teichoic acid, protein, phospholipid, sterol, fatty acid, various enzymes, peptide, amino acid, nucleotide, extracellular polysaccharide and the like, provides rich nutrition for skin, and has good anti-aging effect.
The component 5 is used as skin conditioner, and the extract of oat (AVENA SATIVA) kernel is natural product extracted from oat kernel, and has effects of whitening skin, keeping moisture and caring skin. Can promote the growth of natural collagen and improve the elasticity of skin. Also has antioxidant effect, and is effective in delaying skin aging. Can be used as antioxidant and humectant in daily chemical products.
Component 6 is used as skin conditioner, and the extract of brown algae (PHYLLACANTHA FIBROSA) mainly contains alginate jelly, vitamins, amino acids, etc. The brown algae (PHYLLACANTHA FIBROSA) extract is natural moisturizing emollient, has effects of promoting cell regeneration, enhancing skin metabolism, removing cutin, refreshing skin, and preventing wrinkle.
Component 7 is used as humectant, glycerin, softening, moisturizing, makeup removing solvent and lubricant. Undiluted 100% pure glycerol can never be used directly, which would have adverse effects. Glycerol has a water-absorbing effect, and is often used in moisturizing skin care products to absorb water molecules in the air, so that the stratum corneum of the skin covered by the moisturizing skin care product is kept moist.
The component 8 is used as skin conditioner, and hydrolyzed soybean protein thereof has high-efficiency moisturizing effect and is used as moisturizing agent and skin conditioner. The hydrolyzed soy protein is helpful for inducing skin to generate hyaluronic acid, commonly called hyaluronic acid, and is an ideal natural moisturizing factor and a natural component for promoting skin tissue metabolism and maintenance functions in female bodies. When the content of hyaluronic acid in human skin is gradually reduced day by day, the skin is matured and the aging process is occurring. The hydrolyzed soybean protein can induce the original role and increase the concentration of hyaluronic acid in skin, thereby achieving the effect of high-efficiency moisture retention.
Component 9 is used as skin conditioner, and is extracted from small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit for scavenging and counteracting free radicals; and plays the efficacies of moistening and preserving moisture through the retention and absorption of moisture; additionally, it can improve the appearance of dry/damaged skin, reduce desquamation and restore skin barrier; can be used as antioxidant, humectant and skin conditioner in cosmetics. The propylene glycol belongs to a small molecular moisture-retaining component. Is one kind of polyol, is almost colorless, odorless and non-greasy, is completely dissolved in water, and also has antiseptic effect. Propylene glycol is used as a slip agent, has strong permeability, can help other components to spread and permeate on the surface of the skin, and has low water-holding ratio when being used as a humectant. The addition amount of the propylene glycol is controversial, in general cosmetics, the addition proportion of the propylene glycol does not exceed 5%, skin of a few people can generate a stabbing and burning feeling after the propylene glycol is used, the American FDA considers that the propylene glycol belongs to a cosmetic ingredient which can be safely used, but sensitive skin avoids using the ingredient better, and healthy skin does not need to worry excessively.
The component 10 is used as skin conditioner, and contains extract of black mulberry (Morus NIGRA) root containing reducing sugar, pentosan and galactoside, tannin, and flavonoids. Can inhibit elastase, and has antiaging effect; promoting the synthesis of fiber bud cell brain amide and softening and moistening skin; can well prevent and treat acne caused by high androgen; has contraction effect on collagen fiber, and can be used for reducing weight; promoting the activation of luciferase, and showing that the luciferase has anti-inflammatory efficacy; can inhibit tyrosinase activity, and has skin whitening effect.
The component 11 is used as a humectant, and hyaluronic acid (sodium hyaluronate is also called as sodium hyaluronate), belongs to a skin conditioner, is an acidic mucopolysaccharide, naturally exists in corneal epithelium, can absorb 1000 times of water by the weight of the hyaluronic acid, so as to achieve the purposes of keeping skin water, preventing water from losing through epidermis and repairing barriers when skin is damaged, so that the skin does not feel dry and glossy after being used, can improve skin nutrition metabolism, make the skin soft and smooth, remove wrinkles, increase elasticity and prevent aging, and is a good transdermal absorption promoter while keeping moisture. The nutrient can be used together with other nutrient components to achieve the more ideal effect of promoting nutrient absorption.
The component 12 is used as a solvent, the 1, 2-hexanediol belongs to polyhydric alcohol, and has a bacteriostatic effect, and only when the addition amount is about 5%, the preservative effect is achieved.
The component 13 is used as a skin conditioner, and the allantoin is white powder which is non-toxic, tasteless, non-irritant and non-allergic, is mainly used as a skin conditioner and a protective agent, and can help skin to resist inflammation, relieve and promote cell repair. Allantoin can reduce the adhesion of stratum corneum cells and accelerate epidermal cell renewal. Some cosmetics containing fruit acid and vitamin A with irritation or after-sun repair products with anti-inflammatory and sedative effects are added with allantoin to enhance the repair capability. However, the addition amount of allantoin is about 0.1% to 0.2%, and the addition of an excessive amount also causes a stimulation reaction. But allantoin is an anti-allergic component in general and has high safety.
The component 14 is used as a skin conditioner, and asiaticoside which is a main component of an asiatic pennywort herb (CENTELLA ASIATICA) extract has the function of promoting the activity of scar fibroblasts, so that the asiaticoside has the function of removing scars, has a good polymerization effect with phospholipid substances, has a remarkable effect of removing acnes, has an inhibition effect on glucuronidase and has antibacterial property and a good effect of inhibiting body odor.
Component 15 is used as skin conditioner, and p-hydroxyacetophenone is a natural plant extract, and is naturally present in stems and leaves of Artemisia scoparia of Compositae, and roots of Artemisia capillaris Thunb, Asclepiadaceae, and caulis et folium Tylophorae Repentis. A multifunctional cosmetic ingredient having antioxidant and soothing effects; the preservative can be used as a substitute of the traditional preservative in cosmetics, has the functions of antisepsis and synergism, can promote the efficacy of various preservatives, and has excellent stability in high and low pH and temperature ranges. Can be used in various formulations, including sunscreen and shampoo. It has good compatibility with various cosmetic components and packaging materials.
Component 16 as skin conditioner contains flos Nelumbinis (Nelumbium SPECIOSUM) extract derived from flos Nelumbinis, and has effects in improving skin dark yellow, reducing dry lines, resisting acid, reducing harmful active oxygen, protecting skin cell, and keeping skin cell healthy and lustrous.
The component 17 is used as a PH regulator, lactic acid is also called propanoic acid, belongs to one of fruit acids, is divided into L-lactic acid and D-lactic acid according to different structures, and the L-lactic acid is used as a natural moisturizing factor to be present in the skin of a human body, so that the irritation of the L-lactic acid is smaller than that of other fruit acids, and the L-lactic acid is usually used for products with mild properties such as eye keratocream and the like, and can effectively remove fine lines and wrinkles. It is considered that the tendency of skin exposed to dryness in the leg, elbow, chest, etc. is due to the decrease in L-lactic acid and other moisture-retaining components. L-lactic acid can replace components lost in dry skin. The amount of L-lactic acid used in the cosmetic is about 5%. The effect of D-lactic acid or racemic lactic acid is much worse than that of L-lactic acid. L-lactic acid is contained in fruits such as sugarcane and olive in a large amount.
Component 18 is used as skin conditioner, tripeptide-1 copper, also known as copper trisepeptide, copper bluepitopeptide. The copper peptide and the copper compound thereof can be used as an activator and an antioxidant for tissue remodeling, and the copper peptide is also a signal peptide, so that the degradation of a large number of collagen aggregates outside the scar, the synthesis of normal collagen of the skin, the generation of elastin, proteoglycan and glucosaminan, the growth speed and migration of different cell types, inflammation resistance and antioxidant reaction are promoted.
Component 19 can be used as skin conditioner, and the sunflower (Helianthus ANNUUS) seed is rich in sunflower seed oil, which is important base oil material for cosmetics and has skin lubricating effect. Has activating effect on peroxidase-activated receptor, and has antiinflammatory effect for promoting skin wound healing; can promote decomposition of fat cells, and has effect of reducing weight; has certain inhibition effect on tyrosinase and certain whitening effect.
Component 20 acts as a skin conditioner which hydrolyzes the natural polymers of which the SCLEROTIUM rolfsii (scleritium ROLFSSII) gum belongs to the group of polysaccharides. Also called scleroglucan, is stable at various pH values at high temperature, is a polysaccharide polymer, has good compatibility with skin, can effectively form a film, and has stability.
Component 21 acts as a skin conditioner, sodium gluconate also acts as a chelating agent, and has exfoliating effects.
Fraction 22 as skin conditioner comprises an extract of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) having strong antibacterial properties combined with its anti-inflammatory properties and useful for the treatment of acne; the Achillea millefolium extract has effects of inhibiting elastase, proliferating epidermal keratinocyte, restoring elasticity of skin fiber tissue, balancing and accelerating metabolism of skin cell, and can be used in anti-wrinkle cosmetics; the extract also has certain whitening effect.
The component 23 is used as antioxidant, and has strong antioxidant activity for skin decolorization and spot fading in root and rhizome tissue cells of Glycyrrhiza glabra, and is also main component, i.e. Glycyrrhiza glabra extract and Glycyrrhiza glabra L. It is called "whitening gold". Has strong antioxidant activity, and can be used for skin decolorization and color spot lightening, whitening skin, killing bacteria, lightening color spot, and relieving skin.
Component 24 acts as a skin conditioner and acetyl hexapeptide-8 is a biologically active polypeptide that is effective in reducing existing facial wrinkles and also in preventing new wrinkles. The release of the nerve conduction element acetylcholine (acetylcholine) is inhibited to reduce the contraction of muscles, thereby achieving the purpose of reducing the generation of dynamic lines and expression lines.
Component 25 is used as skin conditioner, and ascorbic acid (vitamin C) is also called L-ascorbic acid, L-D-vitamin C, L-vitamin C, is natural antioxidant, and can be used for preventing and treating skin sunburn. The human body itself cannot produce vitamin C and must be ingested from the outside. In cosmetics, vitamin C interacts with copper ions at the tyrosinase active part to reduce the multi-step melanin synthesis processes such as dopaquinone and the like to interfere the generation of melanin, and has good whitening and freckle removing effects. Also has anti-inflammatory effect. At present, L-ascorbic acid is still the most biologically active and most studied. L-ascorbic acid is a hydrophilic and labile molecule that is not very permeable in the skin due to the hydrophobic nature of the stratum corneum; again, since L-ascorbic acid is a charged molecule, this instability further limits its transdermal penetration. An effective method is to achieve the conversion of the L-ascorbic acid molecule from a charged to uncharged molecular form by the addition of ferulic acid, while reducing the acidity of the L-ascorbic acid to below 3.5, meaning that the L-ascorbic acid is able to remain stable and penetrate the stratum corneum.
Component 26 is used as skin conditioner, and Kappaphycus alvarezii extract belongs to red algae. Contains multiple vitamins and colloid. Can moisturize, maintain the elasticity of skin, ensure the smoothness and the elasticity of the skin, moisturize and lock water, and nourish the skin.
Component 27 is used as a skin conditioner whose extract of Phragmites communis (PHRAGMITES COMMUNIS) has antibacterial and antioxidant properties. The reed extract has the best effect on inhibiting escherichia coli in various strains, and has higher inhibition on bacteria than mould; the aloe extract has obvious antioxidant effect, and the higher the concentration of the total flavone in the oil sample is along with the increase of the adding concentration of the aloe extract, the smaller the increase of the POV value of the oil sample is when the oil sample is induced for the same days, namely the antioxidant effect is positively correlated with the dosage range.
Component 28 is used as skin conditioner, and Poria (Poria COCOS) extract has proliferation promoting effect on integrin which can represent proliferation of fibroblast and adhesion between cell and fibrin, and can reduce diameter and volume of collagen coated by fibroblast, thereby having contraction effect, and can be used in skin tightening and fine line cosmetics; has antibacterial property, and has good inhibitory effect on various bacteria and fungi; it also has anti-inflammatory and moisture keeping effects.
Component 29 is used as a skin conditioner, and pentapeptide-3 is a modified peptide having lipophilicity, and is effective in alleviating facial muscle contraction, increasing the arrangement of collagen and elastin, thereby preventing the formation of wrinkles and wrinkles in the skin, and maintaining the firm state of the skin.
Component 30 acts as a chelating agent, disodium EDTA has a stabilizing effect in cosmetics, and a mineral chelating agent, which synergistically preserves the preservative effect. And has a certain synergistic effect on an anticorrosion system and an antioxidant system.
The INCI names corresponding to the components are as follows:
the preparation method of the blue ketone peptide repair essence comprises the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 7, the component 12, the component 13, the component 15, the component 20 and the component 30 into an emulsion pot water phase pot, stirring, heating to 80-90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
s2, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 5 minutes or more, and preserving heat for more than 20 minutes to obtain a second intermediate;
s3, opening cooling water, cooling the second intermediate to 65-70 ℃, adding the component 11, and homogenizing for 5 minutes or more to obtain a third intermediate;
s3, cooling the third intermediate to 55-60 ℃, and then sequentially adding the following formula numbers: stirring and dissolving the component 14, the component 17, the component 21 and the component 23 to obtain a fourth intermediate;
S4, cooling the fourth intermediate to 40-45 ℃, and then sequentially adding the following formula numbers: component 4, component 5, component 6, component 8, component 9, component 10, component 16, component 18, component 19, component 22, component 24, component 25, component 26, component 27, component 28, component 29, stirring to dissolve completely to obtain a fifth intermediate;
and S4, cooling the fifth intermediate to 35-40 ℃, stopping stirring, filtering with filter cloth of 100 meshes or more, and discharging. The applicant has designed the above preparation method because the components can withstand different temperatures and need to be dissolved and mixed one by one according to the principle of similar solubility. The method can ensure the activity of each component on the premise of ensuring that each component is fully dissolved and mixed, thereby ensuring the efficacy of a final finished product.
The invention has the beneficial effects that: the invention adopts pure plant extracts as the conditioner, can deeply nourish the skin, and keeps each medicinal preparation in a reasonable range, thereby not only ensuring effective conditioning, but also not generating stronger side effect.
The skin care product can keep moisture and moisten, has fresh skin feeling, is not sticky, has good moistening degree, and effectively repairs damaged skin and the thickness of a skin cutin layer. Tripeptide-1 copper has a specific blue color, is not a pigment, and can influence the color due to pH change, and can well synergize when being compounded with other raw materials.
Detailed Description
The invention is further illustrated by the following examples:
example one
The blue ketone peptide repairing essence comprises the following components in parts by weight:
component 1: water 73.48
And (2) component: 1, 3-propanediol 5
And (3) component: butanediol 3
And (4) component: lactic acid bacteria fermentation lysis mixture 3
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.8
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.8
And (4) component 7: glycerol 2.5
And (4) component 8: hydrolyzed soy protein mixture 1.5
And (3) component 9: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract mixture 1
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.9
The components of (11): hyaluronic acid 0.6
And (2) component 12: 0.6 parts of 1, 2-hexanediol
A component 13: allantoin 0.5
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.4
The components of 15: p-hydroxyacetophenone 0.4
The components of 16: extract mixture of flos Nelumbinis (Nelumbium SPECIOSUM) 0.4
A component 17: lactic acid 0.3
The components of 18: tripeptide-1 copper 0.2
A component 19: semen Helianthi (Helianthus ANNUUS) 0.1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.1
The components of 21: sodium gluconate 0.1
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.1
Component 23: glycyrrhiza glabra 0.05
And (3) component 24: acetyl hexapeptide-80.05
Component 25: ascorbic acid (vitamin C)0.05
The component (26): kappaphycus alvarezii extract 0.03
The components of 27: extract mixture of Phragmites communis (PHRAGMITES COMMUNIS) 0.01
Component 28: poria (Poria COCOS) extract mixture 0.01
The component (29): pentapeptide-30.01
30 parts of a component: disodium EDTA 0.01;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 70, water 30;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 90, water 10;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: 50 parts of brown algae (PHYLLACANTHA FIBROSA) extract and 50 parts of water;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 40, water 60;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: extract of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 30, water 50, propylene glycol 20;
the components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 30, water 70;
The components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 40, and water 60;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 35, water 65;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 40, water 60;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 40, and water 60.
Example two
The blue ketone peptide repairing essence comprises the following components in parts by weight:
component 1: water 72
And (2) component: 1, 3-propanediol 4.5
And (3) component: butanediol 3.2
And (4) component: lactobacillus fermentation lysis mixture 3.2
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.2
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.2
And (4) component 7: glycerol 2.2
And (4) component 8: hydrolyzed soy protein mixture 1.3
And (3) component 9: extract mixture of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 0.7
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.7
The components of (11): hyaluronic acid 0.45
And (2) component 12: 0.45% of 1, 2-hexanediol
A component 13: allantoin 0.45
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.45
The components of 15: p-hydroxyacetophenone 0.45
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.45
A component 17: lactic acid 0.45
The components of 18: tripeptide-1 copper 0.15
A component 19: semen Helianthi (Helianthus ANNUUS) 0.08
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.08
The components of 21: sodium gluconate 0.08
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.08
Component 23: glycyrrhiza glabra 0.055
And (3) component 24: acetyl hexapeptide-80.055
Component 25: ascorbic acid (vitamin C)0.055
The component (26): kappaphycus alvarezii extract 0.033
The components of 27: phragmites communis (PHRAGMITES COMMUNIS) extract mixture 0.008
Component 28: poria (Poria COCOS) extract mixture 0.008
The component (29): pentapeptide-30.008
30 parts of a component: disodium EDTA 0.008;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 72, water 28;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 88, water 12;
And (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 54, water 46;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 42, water 58;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract 32, water 53, propylene glycol 15;
the components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, water 71;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 42, and water 58;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 37, water 63;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 42, water 58;
Component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 42, and water 58.
EXAMPLE III
The blue ketone peptide repairing essence comprises the following components in parts by weight:
component 1: water 71
And (2) component: 1, 3-propanediol 5.8
And (3) component: butanediol 3.6
And (4) component: lactobacillus fermentation lysis mixture 3.2
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.4
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.4
And (4) component 7: glycerol 2.4
And (4) component 8: hydrolyzed soy protein mixture 1.2
And (3) component 9: extract mixture of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 1.1
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.7
The components of (11): hyaluronic acid 0.66
And (2) component 12: 0.66 parts of 1, 2-hexanediol
A component 13: allantoin 0.66
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.38
The components of 15: p-hydroxyacetophenone 0.38
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.38
A component 17: lactic acid 0.38
The components of 18: tripeptide-1 copper 0.13
A component 19: semen Helianthi (Helianthus ANNUUS) 0.11
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.11
The components of 21: sodium gluconate 0.11
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.11
Component 23: glycyrrhiza glabra 0.056
And (3) component 24: acetyl hexapeptide-80.056
Component 25: ascorbic acid (vitamin C)0.056
The component (26): kappaphycus alvarezii extract 0.034
The components of 27: extract mixture of Phragmites communis (PHRAGMITES COMMUNIS) 0.009
Component 28: poria (Poria COCOS) extract mixture 0.009
The component (29): pentapeptide-30.009
30 parts of a component: disodium EDTA 0.009;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 71, water 29;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 91, water 9;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 53, water 47;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 39, water 61;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract 29, water 52, propylene glycol 19;
The components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, water 71;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 39, and water 61;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 39, water 61;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 39, water 61;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 39, and water 61.
Example four
A preparation method of a blue ketone peptide repair essence comprises the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 7, the component 12, the component 13, the component 15, the component 20 and the component 30 into an emulsion pot water phase pot, stirring at a stirring speed of 50 revolutions per minute, stirring and heating to 90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
S2, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 3000 revolutions per minute for 5 minutes, stirring for 40 revolutions per minute, and preserving heat for more than 20 minutes to obtain a second intermediate;
s3, opening cooling water, cooling the second intermediate to 70 ℃, adding the component 11, homogenizing for more than 5 minutes, and homogenizing at 3000 r/min to obtain a third intermediate;
s3, cooling the third intermediate to 60 ℃, and then sequentially adding the formula numbers: stirring and dissolving the component 14, the component 17, the component 21 and the component 23 to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 45 ℃, and then sequentially adding the following formula numbers: component 4, component 5, component 6, component 8, component 9, component 10, component 16, component 18, component 19, component 22, component 24, component 25, component 26, component 27, component 28, component 29, stirring to dissolve completely to obtain a fifth intermediate;
and S4, cooling the fifth intermediate to 40 ℃, stopping stirring, and filtering and discharging the product by using filter cloth with 100 meshes or more.
The invention is not described in detail, but is well known to those skilled in the art.
The foregoing detailed description of the preferred embodiments of the invention has been presented. It should be understood that numerous modifications and variations could be devised by those skilled in the art in light of the present teachings without departing from the inventive concepts. Therefore, the technical solutions available to those skilled in the art through logic analysis, reasoning and limited experiments based on the prior art according to the concept of the present invention should be within the scope of protection defined by the claims.
Claims (9)
1. The blue ketone peptide repairing essence is characterized by comprising the following components in parts by weight:
component 1: 70-75 parts of water
And (4) component: lactic acid bacteria fermentation lysis mixture 2-4
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2-3
And (4) component 6: extracting mixture 2-3 of brown algae (PHYLLACANTHA FIBROSA)
And (4) component 8: hydrolyzed soy protein mixture 1-2
And (3) component 9: the extract mixture of small broad-leaved fructus Caricae (SYZYGIUM LUEHMANNII) fruit is 0.5-1.2
The components of 10: 0.6-1 part of extract mixture of root of black mulberry (Morus NIGRA)
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.3-0.5
The components of 18: tripeptide-1 copper 0.1-0.2
The components of 22: extract of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) 0.05-0.12
The components of 27: the extract mixture of rhizoma Phragmitis (PHRAGMITES COMMUNIS) is 0.005-0.011
Component 28: poria (Poria COCOS) extract mixture 0.005-0.011.
2. The blue ketone peptide repair essence according to claim 1, further comprising the following components in parts by weight:
and (2) component: 1, 3-propanediol 4-6
And (3) component: 2-4 parts of butanediol.
And (4) component 7: glycerol 2-3
The components of (11): hyaluronic acid 0.4-0.7
And (2) component 12: 0.4-0.7% of 1, 2-hexanediol
A component 13: allantoin 0.4-0.7
The components of 15: 0.3-0.5 of p-hydroxyacetophenone
A component 17: lactic acid 0.3-0.5
The components of 21: sodium gluconate 0.05-0.12
Component 23: 0.04-0.06 of Glycyrrhiza glabra
And (3) component 24: acetyl hexapeptide-80.04-0.06
Component 25: ascorbic acid (vitamin C) 0.04-0.06
The component (26): kappaphycus alvarezii extract 0.02-0.04
The component (29): pentapeptide-30.005-0.011
30 parts of a component: disodium EDTA 0.005-0.011.
3. The blue ketone peptide repair essence according to claim 1 or 2, further comprising the following components in parts by weight:
component 14: centella asiatica (CENTELLA ASIATICA) extract 0.3-0.5
A component 19: semen Helianthi (Helianthus ANNUUS) 0.05-0.12
The components are as follows: hydrolyzing SCLEROTIUM rolfsii (scleratorium ROLFSSII) gum 0.05-0.12.
4. The cyanamide peptide rejuvenating concentrate as claimed in claim 3 wherein the ratio of component 4: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: 68-76 of lactobacillus fermentation lysate and 24-32 of water;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: 85-92 parts of oat (AVENA SATIVA) kernel extract and 8-15 parts of water;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: 45-55 parts of brown algae (PHYLLACANTHA FIBROSA) extract and 45-55 parts of water;
And (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: 38-44 parts of hydrolyzed soy protein and 56-62 parts of water;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: 28-34 parts of small broad-leaved cherry (SYZYGIUM LUEHMANNII) fruit extract, 48-55 parts of water and 11-24 parts of propylene glycol;
the components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: 28-32 parts of black mulberry (MORUS NIGRA) root extract and 68-72 parts of water;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: 38-44% of flos Nelumbinis (Nelumbium SPECIOSUM) extract and 56-62% of water;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: 34-38 parts of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract, 62-66 parts of water;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: 38-44 parts of reed (PHRAGMITES COMMUNIS) extract and 56-62 parts of water;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: 38-44 parts of PORIA COCOS (Poria COCOS) extract and 56-62 parts of water.
5. The blue ketone peptide repair essence according to claim 4, which is prepared from the following components in parts by weight:
component 1: water 72
And (2) component: 1, 3-propanediol 4.5
And (3) component: butanediol 3.2
And (4) component: lactobacillus fermentation lysis mixture 3.2
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.2
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.2
And (4) component 7: glycerol 2.2
And (4) component 8: hydrolyzed soy protein mixture 1.3
And (3) component 9: extract mixture of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 0.7
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.7
The components of (11): hyaluronic acid 0.45
And (2) component 12: 0.45% of 1, 2-hexanediol
A component 13: allantoin 0.45
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.45
The components of 15: p-hydroxyacetophenone 0.45
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.45
A component 17: lactic acid 0.45
The components of 18: tripeptide-1 copper 0.15
A component 19: semen Helianthi (Helianthus ANNUUS) 0.08
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.08
The components of 21: sodium gluconate 0.08
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.08
Component 23: glycyrrhiza glabra 0.055
And (3) component 24: acetyl hexapeptide-80.055
Component 25: ascorbic acid (vitamin C) 0.055
The component (26): kappaphycus alvarezii extract 0.033
The components of 27: phragmites communis (PHRAGMITES COMMUNIS) extract mixture 0.008
Component 28: poria (Poria COCOS) extract mixture 0.008
The component (29): pentapeptide-30.008
30 parts of a component: disodium EDTA 0.008;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 72, water 28;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 88, water 12;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 54, water 46;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 42, water 58;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract 32, water 53, propylene glycol 15;
the components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, water 71;
The components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 42, and water 58;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 37, water 63;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 42, water 58;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 42, and water 58.
6. The blue ketone peptide repair essence according to claim 4, which is prepared from the following components in parts by weight:
component 1: water 71
And (2) component: 1, 3-propanediol 5.8
And (3) component: butanediol 3.6
And (4) component: lactobacillus fermentation lysis mixture 3.2
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.4
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.4
And (4) component 7: glycerol 2.4
And (4) component 8: hydrolyzed soy protein mixture 1.2
And (3) component 9: extract mixture of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 1.1
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.7
The components of (11): hyaluronic acid 0.66
And (2) component 12: 0.66 parts of 1, 2-hexanediol
A component 13: allantoin 0.66
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.38
The components of 15: p-hydroxyacetophenone 0.38
The components of 16: extract of flos Nelumbinis (Nelumbium SPECIOSUM) 0.38
A component 17: lactic acid 0.38
The components of 18: tripeptide-1 copper 0.13
A component 19: semen Helianthi (Helianthus ANNUUS) 0.11
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.11
The components of 21: sodium gluconate 0.11
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.11
Component 23: glycyrrhiza glabra 0.056
And (3) component 24: acetyl hexapeptide-80.056
Component 25: ascorbic acid (vitamin C) 0.056
The component (26): kappaphycus alvarezii extract 0.034
The components of 27: extract mixture of Phragmites communis (PHRAGMITES COMMUNIS) 0.009
Component 28: poria (Poria COCOS) extract mixture 0.009
The component (29): pentapeptide-30.009
30 parts of a component: disodium EDTA 0.009;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 71, water 29;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 91, water 9;
And (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: brown algae (PHYLLACANTHA FIBROSA) extract 53, water 47;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 39, water 61;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract 29, water 52, propylene glycol 19;
the components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 29, water 71;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 39, and water 61;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 39, water 61;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 39, water 61;
Component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 39, and water 61.
7. The blue ketone peptide repair essence according to claim 4, which comprises the following components in parts by weight:
component 1: water 73.48
And (2) component: 1, 3-propanediol 5
And (3) component: butanediol 3
And (4) component: lactic acid bacteria fermentation lysis mixture 3
And (5) component: oat (AVENA SATIVA) kernel extract mixture 2.8
And (4) component 6: brown algae (PHYLLACANTHA FIBROSA) extraction mixture 2.8
And (4) component 7: glycerol 2.5
And (4) component 8: hydrolyzed soy protein mixture 1.5
And (3) component 9: small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit extract mixture 1
The components of 10: black mulberry (Morus NIGRA) root extract mixture 0.9
The components of (11): hyaluronic acid 0.6
And (2) component 12: 0.6 parts of 1, 2-hexanediol
A component 13: allantoin 0.5
Component 14: centella asiatica (CENTELLA ASIATICA) extract 0.4
The components of 15: p-hydroxyacetophenone 0.4
The components of 16: extract mixture of flos Nelumbinis (Nelumbium SPECIOSUM) 0.4
A component 17: lactic acid 0.3
The components of 18: tripeptide-1 copper 0.2
A component 19: semen Helianthi (Helianthus ANNUUS) 0.1
The components are as follows: hydrolyzed SCLEROTIUM rolfsii (scleritium ROLFSSII) gum 0.1
The components of 21: sodium gluconate 0.1
The components of 22: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract mixture 0.1
Component 23: glycyrrhiza glabra 0.05
And (3) component 24: acetyl hexapeptide-80.05
Component 25: ascorbic acid (vitamin C) 0.05
The component (26): kappaphycus alvarezii extract 0.03
The components of 27: extract mixture of Phragmites communis (PHRAGMITES COMMUNIS) 0.01
Component 28: poria (Poria COCOS) extract mixture 0.01
The component (29): pentapeptide-30.01
30 parts of a component: disodium EDTA 0.01;
and (4) component: the lactobacillus fermentation lysis mixture is prepared by mixing the following components in percentage by weight: lactobacillus fermentation lysate 70, water 30;
and (5) component: the oat (AVENA SATIVA) kernel extract mixture is prepared by mixing the following components in parts by weight: oat (AVENA SATIVA) kernel extract 90, water 10;
and (4) component 6: the brown algae (PHYLLACANTHA FIBROSA) extraction mixture is prepared by mixing the following components in parts by weight: 50 parts of brown algae (PHYLLACANTHA FIBROSA) extract and 50 parts of water;
and (4) component 8: the hydrolyzed soy protein mixture is prepared by mixing the following components in percentage by weight: hydrolyzed soy protein 40, water 60;
and (3) component 9: the extraction mixture of small broad-leaved cherry (SYZYGIUM LUEHMANNII) is prepared by mixing the following components in parts by weight: extract of small broad leaf cherry (SYZYGIUM LUEHMANNII) fruit 30, water 50, propylene glycol 20;
The components of 10: the black mulberry (MORUS NIGRA) root extraction mixture is prepared by mixing the following components in parts by weight: black mulberry (MORUS NIGRA) root extract 30, water 70;
the components of 16: the lotus (Nelumbium SPECIOSUM) flower extract mixture is prepared by mixing the following components in parts by weight: flos Nelumbinis (Nelumbium SPECIOSUM) extract 40, and water 60;
the components of 22: the extract mixture of Achillea MILLEFOLIUM (Achillea MILLEFOLIUM) is prepared by mixing the following components in parts by weight: achillea MILLEFOLIUM (Achillea MILLEFOLIUM) extract 35, water 65;
the components of 27: the reed (PHRAGMITES COMMUNIS) extraction mixture is prepared by mixing the following components in percentage by weight: reed (PHRAGMITES COMMUNIS) extract 40, water 60;
component 28: the PORIA COCOS (PORIA COCOS) extract mixture is prepared by mixing the following components in parts by weight: poria (Poria COCOS) extract 40, and water 60.
8. The preparation method of the blue ketone peptide repair essence is characterized by comprising the following steps:
s1, sequentially putting the component 1, the component 2, the component 3, the component 7, the component 12, the component 13, the component 15, the component 20 and the component 30 into an emulsion pot water phase pot, stirring, heating to 80-90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
S2, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 5 minutes or more, and preserving heat for more than 20 minutes to obtain a second intermediate;
s3, opening cooling water, cooling the second intermediate to 65-70 ℃, adding the component 11, and homogenizing for 5 minutes or more to obtain a third intermediate;
s3, cooling the third intermediate to 55-60 ℃, and then sequentially adding the following formula numbers: stirring and dissolving the component 14, the component 17, the component 21 and the component 23 to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 40-45 ℃, and then sequentially adding the following formula numbers: component 4, component 5, component 6, component 8, component 9, component 10, component 16, component 18, component 19, component 22, component 24, component 25, component 26, component 27, component 28, component 29, stirring to dissolve completely to obtain a fifth intermediate;
and S4, cooling the fifth intermediate to 35-40 ℃, stopping stirring, filtering with filter cloth of 100 meshes or more, and discharging.
9. The method of claim 8, comprising the steps of:
s1, sequentially putting the component 1, the component 2, the component 3, the component 7, the component 12, the component 13, the component 15, the component 20 and the component 30 into an emulsion pot water phase pot, stirring at a stirring speed of 50 revolutions per minute, stirring and heating to 90 ℃, and keeping for more than 20 minutes to obtain a first intermediate;
S2, vacuumizing the heated first intermediate into a main emulsifying pot, homogenizing for 3000 revolutions per minute for 5 minutes, stirring for 40 revolutions per minute, and preserving heat for more than 20 minutes to obtain a second intermediate;
s3, opening cooling water, cooling the second intermediate to 70 ℃, adding the component 11, homogenizing for more than 5 minutes, and homogenizing at 3000 r/min to obtain a third intermediate;
s3, cooling the third intermediate to 60 ℃, and then sequentially adding the formula numbers: stirring and dissolving the component 14, the component 17, the component 21 and the component 23 to obtain a fourth intermediate;
s4, cooling the fourth intermediate to 45 ℃, and then sequentially adding the following formula numbers: component 4, component 5, component 6, component 8, component 9, component 10, component 16, component 18, component 19, component 22, component 24, component 25, component 26, component 27, component 28, component 29, stirring to dissolve completely to obtain a fifth intermediate;
and S4, cooling the fifth intermediate to 40 ℃, stopping stirring, and filtering and discharging the product by using filter cloth with 100 meshes or more.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911236702.9A CN111973481A (en) | 2019-12-05 | 2019-12-05 | Blue ketone peptide repair essence and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911236702.9A CN111973481A (en) | 2019-12-05 | 2019-12-05 | Blue ketone peptide repair essence and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111973481A true CN111973481A (en) | 2020-11-24 |
Family
ID=73441643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201911236702.9A Withdrawn CN111973481A (en) | 2019-12-05 | 2019-12-05 | Blue ketone peptide repair essence and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111973481A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113116753A (en) * | 2021-04-23 | 2021-07-16 | 厦门力嘉诚生物科技有限公司 | Rose essential oil face cream and preparation method thereof |
| CN113943343A (en) * | 2021-10-15 | 2022-01-18 | 广州奥利生物科技有限公司 | Blue copper peptide with anti-aging and repairing effects and preparation method and application thereof |
| CN114948777A (en) * | 2022-05-25 | 2022-08-30 | 浙江妆芝美科技有限公司 | Refreshing and relieving emulsion and preparation method thereof |
| CN115300440A (en) * | 2022-08-11 | 2022-11-08 | 完美（广东）日用品有限公司 | Composition for inhibiting cell damage and application thereof |
-
2019
- 2019-12-05 CN CN201911236702.9A patent/CN111973481A/en not_active Withdrawn
Non-Patent Citations (2)
| Title |
|---|
| 匿名: "CEMOY夜间极光晚安精华", 《网址：HTTP://COSDNA.COM/CHS/COSMETIC_817C413520.HTML》, 7 January 2019 (2019-01-07) * |
| 澳大利亚沃特利制药有效公司: "CEMOY 赋活晚安精华", 《进口普通化妆品备案信息》, 7 March 2019 (2019-03-07) * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113116753A (en) * | 2021-04-23 | 2021-07-16 | 厦门力嘉诚生物科技有限公司 | Rose essential oil face cream and preparation method thereof |
| CN113116753B (en) * | 2021-04-23 | 2022-06-03 | 厦门力嘉诚生物科技有限公司 | Rose essential oil face cream and preparation method thereof |
| CN113943343A (en) * | 2021-10-15 | 2022-01-18 | 广州奥利生物科技有限公司 | Blue copper peptide with anti-aging and repairing effects and preparation method and application thereof |
| CN114948777A (en) * | 2022-05-25 | 2022-08-30 | 浙江妆芝美科技有限公司 | Refreshing and relieving emulsion and preparation method thereof |
| CN114948777B (en) * | 2022-05-25 | 2024-02-02 | 浙江妆芝美科技有限公司 | Refreshing and soothing emulsion and preparation method thereof |
| CN115300440A (en) * | 2022-08-11 | 2022-11-08 | 完美（广东）日用品有限公司 | Composition for inhibiting cell damage and application thereof |
| CN115300440B (en) * | 2022-08-11 | 2023-11-24 | 完美（广东）日用品有限公司 | Composition for inhibiting cell injury and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN111973481A (en) | Blue ketone peptide repair essence and preparation method thereof | |
| CN108653013A (en) | A kind of plant moisturizing water profit after-sun frost and preparation method thereof | |
| CN111053709A (en) | Emulsion for camellia seed oil mask, mask and preparation method of mask | |
| CN109771348B (en) | Whitening, moisturizing and wrinkle-removing cream rich in natural product extract components and preparation method thereof | |
| CN113018238A (en) | Anti-bacterial, anti-inflammatory, refreshing and skin-benefiting acne-removing gel and preparation method thereof | |
| CN111973486A (en) | Ceramide moisturizing and moisture-keeping cream and preparation method thereof | |
| KR20100039532A (en) | Hydrogel composition for healing atopy and matrix patch for healing atopy using the hydrogel composition as a matrix | |
| CN112842943A (en) | Itching-relieving moisturizing skin-repairing cream and preparation method thereof | |
| KR101142541B1 (en) | Anti-wrinkle cosmetic composition containing oriental herb extract treated by enzyme and its extraction method | |
| CN111973501A (en) | Ceramide activation milk and preparation method thereof | |
| CN111603426A (en) | Moisturizing mask and preparation method thereof | |
| CN115501143A (en) | Anti-allergy and relieving composition containing saussurea involucrata culture and preparation method thereof | |
| KR20230152511A (en) | Cosmetic composition in relieving skin for skin regenerating, Manufacturing method thereof, and Cosmetics containing the same | |
| CN104248548A (en) | Plant extract-containing oxidation-resistant essence | |
| CN111973544A (en) | Carnosine firming lifting mask and preparation method thereof | |
| CN113679640A (en) | Natural nourishing skin-cleaning skin-care acne-removing facial cleansing gel and preparation method thereof | |
| CN111973523A (en) | Anti-allergy purslane repairing mask and preparation method thereof | |
| CN108553365A (en) | A kind of apple myofilament sliding surface film and preparation method thereof | |
| CN113398056A (en) | Biological plant extract skin beautifying mask cream and preparation method thereof | |
| CN111973487A (en) | Ceramide moisturizing essence and preparation method thereof | |
| CN112057386A (en) | Refreshing, moisturizing, whitening and repairing sun block and preparation method thereof | |
| CN112402308A (en) | Multi-effect relieving moisturizing lotion and preparation method thereof | |
| CN112716838A (en) | Rose essential oil eye repairing and tightening essence and preparation method thereof | |
| CN112472629A (en) | Alpinia officinarum and amomum tsao-ko sun-proof emulsion and preparation method thereof | |
| CN111973496A (en) | Seaweed moisturizing mask and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20201124 |
|
| WW01 | Invention patent application withdrawn after publication |