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CN111920890B - Wound repair paste and preparation method thereof - Google Patents

Wound repair paste and preparation method thereof Download PDF

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Publication number
CN111920890B
CN111920890B CN202010888860.9A CN202010888860A CN111920890B CN 111920890 B CN111920890 B CN 111920890B CN 202010888860 A CN202010888860 A CN 202010888860A CN 111920890 B CN111920890 B CN 111920890B
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parts
medicinal
stirring
oil
mixture
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CN111920890A (en
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张军
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Junkai Doctor Group (Shenzhen) Co.,Ltd.
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K2236/35Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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Abstract

The application provides a wound repair paste and a preparation method thereof, and relates to the technical field of medicines. A wound repair paste comprising the following raw materials: chinese angelica, coptis, safflower, myrrh, dragon's blood, frankincense, baical skullcap root, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, stilbene, gardenia, mongolian snakegourd root, borneol, medical zinc oxide powder, sesame oil and vaseline, has the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation, and can effectively treat and repair various wounds which are difficult to heal. In addition, the application also provides a preparation method of the wound repair paste, which comprises the following steps: the method can fully extract the effective components in the traditional Chinese medicinal materials, so that the medicinal materials are matched with each other, the medicinal effect is improved, the use effect is enhanced, and the method is beneficial to treatment.

Description

Wound repair paste and preparation method thereof
Technical Field
The application relates to the technical field of medicines, in particular to a wound repair paste and a preparation method thereof.
Background
Open injury, which refers to injury of internal tissues (such as muscle, bone, etc.) of an injured part communicated with the outside; in short, it is a wound such as an abrasion, a laceration, a incised wound, a stab wound, etc. where blood can flow outwards or muscle or bone is exposed. Open injury is common in normal times or war time, and is polluted due to the fact that the injury is polluted due to the fact that the treatment is not timely or improper, infection is easy to occur, healing and functional recovery are affected, and serious patients can cause disability and even endanger lives of wounded persons.
The existing plaster for treating and repairing wounds on the market has the problems of single effect, poor efficacy, discomfort caused by use and the like.
Disclosure of Invention
The application aims to provide a wound repair paste which has the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation, and can treat and repair various wounds which are difficult to heal.
The application also aims to provide a preparation method of the wound repair paste, which can fully extract the effective components in the traditional Chinese medicinal materials, so that the medicinal materials are matched with each other, the efficacy is improved, the use effect is enhanced, and the wound repair paste is beneficial to treatment.
The application solves the technical problems by adopting the following technical scheme.
In one aspect, embodiments of the present application provide a wound repair paste comprising the following raw materials: angelica sinensis, coptis chinensis, safflower, myrrh, dragon's blood, frankincense, radix scutellariae, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, stilbene, gardenia, radix trichosanthis, borneol, medical zinc oxide powder, sesame oil and vaseline.
In another aspect, the present application provides a method for preparing a wound repair paste, comprising the steps of:
pretreatment of traditional Chinese medicine: cleaning radix Angelicae sinensis, coptidis rhizoma, carthami flos, myrrha, sanguis Draxonis, olibanum, scutellariae radix, notoginseng radix, os Draconis preparata, radix Paeoniae Rubra, rhizoma corydalis, flos Lonicerae, radix astragali, fructus Gardeniae, and Trichosanthis radix by ultrasonic, drying, cutting, and stirring to obtain medicinal material mixture;
extracting medicinal oil: pouring sesame oil into a container for heating, then placing the mixture of the medicinal materials, heating and stirring the mixture continuously to make the interior of the mixture of the medicinal materials brown, then cooling the mixture of the medicinal materials, and fishing out the mixture of the medicinal materials to obtain medicinal oil;
the plaster is prepared by the following steps: heating, melting and preserving the heat of Vaseline, adding the medicinal oil while stirring, adding medical zinc oxide powder while stirring, naturally cooling, adding borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Compared with the prior art, the embodiment of the application has at least the following advantages or beneficial effects:
for a first aspect, there is provided a wound repair paste comprising the following raw materials: angelica sinensis, coptis chinensis, safflower, myrrh, dragon's blood, frankincense, radix scutellariae, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, stilbene, gardenia, radix trichosanthis, borneol, medical zinc oxide powder, sesame oil and vaseline.
The wound repair paste adopts the raw materials of angelica, coptis, safflower, myrrh, dragon's blood, frankincense, baical skullcap root, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, astragalus root, gardenia, mongolian snakegourd root, borneol, medical zinc oxide powder, sesame oil, vaseline and the like, and when in use, the baical skullcap root and golden flower can dispel wind and remove dampness; the combination of safflower, myrrh, dragon's blood, frankincense, pseudo-ginseng, red paeony root and element Hu Bingpian can reduce swelling and remove blood stasis; the other medicinal materials can stop bleeding, relieve pain, promote blood circulation and promote tissue regeneration; the medicinal materials are matched and combined mutually, and the synergistic effect is achieved, so that various wounds which are difficult to heal can be treated and repaired.
Aiming at the second aspect, a preparation method of wound repair paste is provided, which comprises the following steps: pretreatment of traditional Chinese medicine, extraction of medicinal oil and preparation of plaster.
The preparation method of the wound repair paste can fully extract the effective components in the medicinal materials, and the medicinal materials are matched with each other, so that the effect of the medicine is improved, the comfort level in use can be enhanced, the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation can be achieved, various wounds which are difficult to heal can be treated and repaired, the effect is good, the use is convenient, and the storage is convenient.
Detailed Description
In order to make the objects, technical solutions and advantages of the embodiments of the present application more clear, the technical solutions of the embodiments of the present application will be clearly and completely described below. The specific conditions are not noted in the examples and are carried out according to conventional conditions or conditions recommended by the manufacturer. The reagents or apparatus used were conventional products commercially available without the manufacturer's attention.
It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The present application will be described in detail with reference to specific examples.
A wound repair paste comprising the following raw materials: angelica sinensis, coptis chinensis, safflower, myrrh, dragon's blood, frankincense, radix scutellariae, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, stilbene, gardenia, radix trichosanthis, borneol, medical zinc oxide powder, sesame oil and vaseline.
In the above embodiment, the raw materials include angelica, coptis, safflower, myrrh, dragon's blood, frankincense, baikal skullcap root, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, stilbene, gardenia, radix trichosanthis, borneol, medical zinc oxide powder, sesame oil and vaseline, wherein:
chinese angelica root: blood replenishing, menstruation regulating, pain relieving, dryness moistening, intestine smoothing, menoxenia, amenorrhea abdominal pain, abdominal mass accumulation, metrorrhagia, blood deficiency headache, dizziness, paralysis, constipation, red dysentery, carbuncle, sore, and traumatic injury;
coptis root: purging pathogenic fire, eliminating dampness, removing toxic substances, killing parasite, and treating heat toxin, typhoid fever, heat Cheng Xinfan, distention and fullness, vomiting, bacillary dysentery, diarrhea and abdominal pain, lung pressing, vomiting, epistaxis, bleeding, diabetes, malnutrition, ascariasis, pertussis, sore throat, trachoma, aphtha, carbuncle, sore, eczema, and scald;
safflower: promoting blood circulation, dredging channels, removing blood stasis, relieving pain, and treating amenorrhea, abdominal mass, dystocia, stillbirth, puerperal lochia, pain due to blood stasis, carbuncle, swelling, and traumatic injury;
myrrh: promoting blood circulation, relieving pain, detumescence, promoting granulation, and treating chest and abdomen pain, dysmenorrhea, amenorrhea, abdominal mass, traumatic injury, carbuncle, swelling, sore, acute appendicitis, conjunctival congestion, and swelling and pain;
dragon's blood: removing blood stasis, relieving pain, stopping bleeding, promoting granulation, and healing sore, and can be used for treating traumatic injury, internal injury, dysmenorrhea, puerperal abdominal pain, traumatic hemorrhage, scrofula, ecthyma, and hemorrhoid;
mastic gum: promoting blood circulation, activating qi-flowing, dredging channels, relieving pain, detumescence, promoting granulation, and treating heart and abdomen pain, rheumatalgia, amenorrhea dysmenorrhea, traumatic blood stasis and pain, carbuncle, abscess, acute appendicitis, sore, ulcer, and ulcer;
radix Scutellariae Baicalensis: purging excessive fire, removing damp-heat, stopping bleeding, preventing miscarriage, and treating strong heat polydipsia, cough due to lung heat, damp-heat diarrhea, jaundice, heat stranguria, vomiting, epistaxis, metrorrhagia, conjunctival congestion with swelling and pain, fetal irritability, carbuncle, swelling and furuncle;
pseudo-ginseng: promoting blood circulation, removing blood stasis, stopping bleeding, relieving swelling and pain, and treating epistaxis, hematemesis, hemoptysis, hematochezia, functional uterine bleeding, puerperal blood stasis, abdominal pain and traumatic injury;
calcined dragon bone: relieving convulsion, tranquilizing mind, arresting sweating, stopping bleeding, astringing intestine, promoting granulation, and healing sore, and treating convulsion, epilepsy, amnesia, insomnia, dreaminess, spontaneous sweat, night sweat, spermatorrhea, stranguria, epistaxis, hematochezia, metrorrhagia, leukorrhagia, diarrhea, rectocele, and chronic ulcer;
radix paeoniae rubra: clearing heat and cooling blood, promoting blood circulation and removing blood stasis, and treating toxic heat and spot, hematemesis and epistaxis, intestinal wind and blood down, conjunctival congestion and swelling and pain, carbuncle and sores, amenorrhea, dysmenorrhea, leucorrhea with turbid urine, hypochondriac pain due to stasis, hernia and traumatic injury;
rhizoma corydalis: promoting blood circulation, removing blood stasis, regulating qi-flowing, relieving pain, and treating pain of heart, abdomen, waist and knee, menoxenia, abdominal mass, metrorrhagia, puerperal blood dizziness, lochia, traumatic injury;
flower of golden flower: dispelling pathogenic wind, removing dampness, stopping bleeding, removing toxic substances, and treating rheumatalgia, damp-heat dysentery, stagnation, traumatic injury, traumatic hemorrhage, and skin sore furuncle;
yellow stilbene: tonifying and strengthening the exterior, supporting sore and promoting granulation, and treating spontaneous perspiration due to asthenia, chronic diarrhea, rectocele, uterine prolapse, chronic nephritis, edema due to asthenia, chronic ulcer, and open sore with long-term non-healing;
gardenia jasminoides ellis: clearing heat, purging pathogenic fire, cooling blood, and treating febrile dysphoria, insomnia, jaundice, gonorrhea, diabetes, conjunctival congestion, pharyngalgia, hematemesis, epistaxis, bloody dysentery, hematuria, heat toxin sores and ulcers, and sprain swelling and pain;
radix trichosanthis: promoting salivation, quenching thirst, purging pathogenic fire, moistening dryness, expelling pus, and relieving swelling, and can be used for treating fever, thirst, diabetes, jaundice, lung dryness, hemoptysis, carbuncle, swelling, and hemorrhoids and fistula;
borneol: inducing resuscitation, removing stagnated fire, removing nebula, improving eyesight, relieving swelling and pain, and treating middle-jiao wind-port trismus, fever unconsciousness, convulsion, phlegm, qi-block deafness, pharyngitis, aphtha, otitis media, carbuncle, hemorrhoid, nebula, enterobiasis;
medical zinc oxide powder: drawing out toxin, stopping bleeding, promoting tissue regeneration and astringing;
sesame oil: the medicinal oil matrix has good spreadability and penetrability;
vaseline: lubrication and moisture preservation are carried out, so that the use comfort is improved, and the paste is used as a paste matrix;
therefore, when in use, the combination of the baikal skullcap root and the honeysuckle can dispel wind and remove dampness; the combination of safflower, myrrh, dragon's blood, frankincense, pseudo-ginseng, red paeony root and element Hu Bingpian can reduce swelling and remove blood stasis; the other medicinal materials can stop bleeding, relieve pain, promote blood circulation and promote tissue regeneration; the medicinal materials are matched and combined mutually, and the synergistic effect is achieved, so that various wounds which are difficult to heal can be treated and repaired.
In some embodiments of the application, the composition comprises the following raw materials in parts by weight: 5-15 parts of angelica sinensis, 3-5 parts of coptis chinensis, 5-10 parts of safflower, 5-10 parts of myrrh, 5-10 parts of dragon's blood, 5-15 parts of frankincense, 3-10 parts of radix scutellariae, 5-10 parts of pseudo-ginseng, 10-15 parts of calcined dragon's bone, 5-10 parts of red paeony root, 3-10 parts of rhizoma corydalis, 5-10 parts of golden flower, 10-15 parts of stilbene, 5-10 parts of fructus gardeniae, 10-15 parts of radix trichosanthis, 1-3 parts of borneol, 10-15 parts of medical zinc oxide powder, 5-10 parts of sesame oil and 20-50 parts of vaseline.
In the embodiment, the medicinal materials with the weight parts exert effects, can be matched with each other better, have the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation, are beneficial to improving the use effect, and can treat and repair various wounds which are difficult to heal.
In some embodiments of the application, the composition comprises the following raw materials in parts by weight: 10 parts of Chinese angelica, 5 parts of coptis chinensis, 8 parts of safflower, 8 parts of myrrh, 8 parts of dragon's blood, 10 parts of frankincense, 8 parts of baical skullcap root, 10 parts of sanchi, 12 parts of calcined dragon bone, 8 parts of red paeony root, 5 parts of rhizoma corydalis, 6 parts of golden flower, 12 parts of astragalus root, 8 parts of gardenia, 10 parts of mongolian snakegourd root, 3 parts of borneol, 10 parts of medical zinc oxide powder, 50 parts of sesame oil and 50 parts of vaseline.
In the embodiment, the medicinal materials with the weight parts exert effects, can be matched with each other better, have the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation, are beneficial to improving the use effect, and can treat and repair various wounds which are difficult to heal.
A method for preparing a wound repair paste, comprising the steps of:
pretreatment of traditional Chinese medicine: cleaning radix Angelicae sinensis, coptidis rhizoma, carthami flos, myrrha, sanguis Draxonis, olibanum, scutellariae radix, notoginseng radix, os Draconis preparata, radix Paeoniae Rubra, rhizoma corydalis, flos Lonicerae, radix astragali, fructus Gardeniae, and Trichosanthis radix by ultrasonic, drying, cutting, and stirring to obtain medicinal material mixture;
extracting medicinal oil: pouring sesame oil into a container for heating, then placing the mixture of the medicinal materials, heating and stirring the mixture continuously to make the interior of the mixture of the medicinal materials brown, then cooling the mixture of the medicinal materials, and fishing out the mixture of the medicinal materials to obtain medicinal oil;
the plaster is prepared by the following steps: heating, melting and preserving the heat of Vaseline, adding the medicinal oil while stirring, adding medical zinc oxide powder while stirring, naturally cooling, adding borneol while stirring, and fully and uniformly mixing to obtain the plaster.
In the embodiment, firstly, angelica, coptis, safflower, myrrh, dragon's blood, frankincense, baical skullcap root, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, astragalus root, gardenia and radices trichosanthis are cleaned and dried through the pretreatment steps of the traditional Chinese medicines, impurities attached to the medicines are removed, the medicine effect is improved, the medicines are prepared into medicine mixture after being sheared and mixed uniformly, the medicines are fully mixed, then the medicine mixture is put into sesame oil through the medicine oil extraction step and stir-fried to obtain the medicine oil, the active ingredients in the medicines are fully extracted, the active ingredients in the medicines are not destroyed, the medicine oil is added into vaseline through the preparation step of the plaster, medical zinc oxide powder and borneol are added into the plaster, and the plaster is prepared through stirring and mixing uniformly, so that the medicine efficacy can be further improved, the use comfort is improved, and the use and the storage are facilitated. By the method, the effective components in the medicinal materials can be fully extracted, the medicinal materials are matched with each other, the medicinal effect is improved, the comfort level in use can be enhanced, the effects of dispelling wind and promoting diuresis, stopping bleeding and relieving pain, and reducing swelling and promoting granulation can be achieved, various wounds which are difficult to heal can be treated and repaired, the effect is good, the use is convenient, and the storage is convenient.
In some embodiments of the present application, the drying temperature in the pretreatment step of the traditional Chinese medicine is 30-50 ℃.
In the above embodiment, the drying temperature is controlled to be 30-50 ℃, so that the active ingredients in the medicinal materials can be protected from being destroyed during drying, and the medicinal effect can be better improved.
In some embodiments of the present application, in the above-mentioned pretreatment step of the traditional Chinese medicine, the drying temperature is 45 ℃.
In the above embodiment, the drying temperature is controlled to be 45 ℃, so that the active ingredients in the medicinal materials can be better protected from being destroyed during drying, and the medicinal effect can be better improved.
In some embodiments of the present application, in the above-mentioned oil extraction step, sesame oil is poured into a container and heated to 200-250 ℃, then the above-mentioned medicinal material mixture is put in, firstly heated to 300-350 ℃, and continuously stirred, so that the interior of the medicinal material mixture is brown, then cooled to 150-100 ℃, and the medicinal material mixture is fished out, so as to obtain the medicinal oil.
In the above embodiment, firstly, the sesame oil is heated to 200-250 ℃, then the sesame oil is put into the medicinal material mixture, and then the mixture is heated to 300-350 ℃ and stirred, so that the interior of the medicinal material mixture is brown, and then the mixture is cooled to 150-100 ℃, and the medicinal material mixture is fished out to obtain the medicinal oil, so that the effective components in each medicinal material can be fully extracted into the medicinal oil, the mutual coordination among the medicinal materials is facilitated, the medicinal effect can be better improved, and the use effect is enhanced.
In some embodiments of the present application, in the above-mentioned oil extraction step, sesame oil is poured into a container to be heated to 200 ℃, then the above-mentioned medicinal material mixture is put in, firstly heated to 320 ℃, and continuously stirred, so that the interior of the medicinal material mixture is brown, then cooled to 100 ℃, and the medicinal material mixture is fished out, so as to obtain the oil.
In the above embodiment, firstly, the sesame oil is heated to 200 ℃, then the above medicinal material mixture is put in, and then heated to 320 ℃ and stirred, so that the interior of the medicinal material mixture is brown, and then cooled to 100 ℃, and the medicinal material mixture is fished out to obtain the medicinal oil, so that the effective components in the medicinal materials can be fully extracted into the medicinal oil, the mutual coordination among the medicaments is facilitated, the medicinal effect can be better promoted, and the use effect is enhanced.
In some embodiments of the present application, in the preparation step of the plaster, vaseline is heated to 80-90 ℃ for melting and heat preservation, then the medicinal oil is added while stirring, then medical zinc oxide powder is added while stirring, the medical zinc oxide powder is naturally cooled, and then borneol is added while stirring after cooling to 70-60 ℃, and the plaster is prepared after fully and uniformly mixing.
In the embodiment, the vaseline is heated to 80-90 ℃ to be melted and insulated, the medicinal oil is added while stirring, the medical zinc oxide powder is added while stirring, the mixture is naturally cooled, the borneol is added while stirring after cooling to 70-60 ℃, and the plaster is prepared after fully and uniformly mixing, so that the effective components extracted into the medicinal oil can be protected from being damaged, the effects of the medical zinc oxide powder and the borneol can be protected from being damaged, the use effect of the product can be improved, and the use comfort can be improved.
In some embodiments of the present application, in the preparation step of the plaster, vaseline is heated to 85 ℃ for melting and heat preservation, then the medicinal oil is added while stirring, then medical zinc oxide powder is added while stirring, the mixture is naturally cooled, and then borneol is added while stirring after cooling to 60 ℃, and the plaster is prepared after fully and uniformly mixing.
In the embodiment, the plaster is prepared by heating the forest to 85 ℃ for melting and preserving heat, adding the medicinal oil while stirring, adding the medical zinc oxide powder while stirring, naturally cooling, cooling to 60 ℃, adding the borneol while stirring, and fully and uniformly mixing, so that the effective components extracted into the medicinal oil can be better protected from being damaged, the efficacy of the medical zinc oxide powder and the borneol can be better protected from being damaged, the use effect of the product can be further improved, and the use comfort degree can be improved.
The features and capabilities of the present application are described in further detail below in connection with the examples.
Example 1
Pretreatment of traditional Chinese medicine: 15 parts of angelica, 5 parts of coptis chinensis, 10 parts of safflower, 10 parts of myrrh, 10 parts of dragon's blood, 15 parts of frankincense, 10 parts of baical skullcap root, 10 parts of sanchi, 15 parts of calcined dragon's bone, 10 parts of red paeony root, 10 parts of rhizoma corydalis, 10 parts of golden flower, 15 parts of astragalus root, 10 parts of gardenia and 15 parts of mongolian snakegourd root are cleaned by ultrasonic, and then dried at the temperature of 50 ℃, and each medicinal material is sheared after being dried, stirred and mixed uniformly to obtain a medicinal material mixture;
extracting medicinal oil: 60 parts of sesame oil are taken and poured into a container for heating to 250 ℃, then the mixture is put into the container, the mixture is firstly heated to 350 ℃, and is continuously stirred to make the interior of the mixture become brown, then the mixture is cooled to 100 ℃, and the mixture is fished out to obtain medicinal oil;
the plaster is prepared by the following steps: heating 50 parts of Vaseline to 90 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 15 parts of medical zinc oxide powder while stirring, naturally cooling to 70-60 ℃, adding 3 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 2
Pretreatment of traditional Chinese medicine: 5 parts of angelica sinensis, 3 parts of coptis chinensis, 5 parts of safflower, 5 parts of myrrh, 5 parts of dragon's blood, 5 parts of frankincense, 3 parts of baical skullcap root, 5 parts of sanchi, 10 parts of calcined dragon's bone, 5 parts of red paeony root, 3 parts of rhizoma corydalis, 5 parts of golden flower, 10 parts of astragalus root, 5 parts of gardenia and 10 parts of mongolian snakegourd root are cleaned by ultrasonic, and then dried at the temperature of 30 ℃, and each medicinal material is sheared after being dried, stirred and mixed uniformly to obtain a medicinal material mixture;
extracting medicinal oil: pouring 30 parts of sesame oil into a container, heating to 200 ℃, then putting the mixture into the container, heating to 300 ℃ firstly, stirring continuously to make the interior of the mixture become brown, then cooling to 150 ℃, and fishing out the mixture to obtain medicinal oil;
the plaster is prepared by the following steps: heating 20-50 parts of Vaseline to 80 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 10 parts of medical zinc oxide powder while stirring, naturally cooling to 70 ℃, adding 1 part of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 3
Pretreatment of traditional Chinese medicine: 10 parts of Chinese angelica, 4 parts of coptis chinensis, 7 parts of safflower, 7 parts of myrrh, 8 parts of dragon's blood, 10 parts of frankincense, 6 parts of baical skullcap root, 8 parts of sanchi, 12 parts of calcined dragon's bone, 6 parts of red paeony root, 7 parts of rhizoma corydalis, 6 parts of golden flower, 12 parts of astragalus root, 8 parts of gardenia and 12 parts of mongolian snakegourd root are cleaned by ultrasonic, and then dried at the temperature of 40 ℃, and each medicinal material is sheared after being dried, stirred and mixed uniformly to obtain a medicinal material mixture;
extracting medicinal oil: 45 parts of sesame oil are taken and poured into a container for heating to 220 ℃, then the mixture is put into the container, the mixture is firstly heated to 320 ℃ and is continuously stirred, the interior of the mixture is turned into brown, then the mixture is cooled to 120 ℃, and the mixture is fished out to obtain medicinal oil;
the plaster is prepared by the following steps: heating 40 parts of Vaseline to 85 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 12 parts of medical zinc oxide powder while stirring, naturally cooling to 65 ℃, adding 2 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 4
Pretreatment of traditional Chinese medicine: taking 7 parts of angelica sinensis, 4 parts of coptis chinensis, 6 parts of safflower, 6 parts of myrrh, 6 parts of dragon's blood, 8 parts of frankincense, 5 parts of baical skullcap root, 6 parts of sanchi, 12 parts of calcined dragon's bone, 6 parts of red paeony root, 5 parts of rhizoma corydalis, 6 parts of golden flower, 12 parts of astragalus membranaceus, 6 parts of gardenia and 12 parts of mongolian snakegourd root, cleaning by ultrasonic, drying at 35 ℃, cutting each medicinal material after drying, and uniformly stirring to obtain a medicinal material mixture;
extracting medicinal oil: pouring 40 parts of sesame oil into a container, heating to 210 ℃, then putting the mixture into the container, heating to 310 ℃ firstly, stirring continuously to make the interior of the mixture become brown, then cooling to 110 ℃, and fishing out the mixture to obtain medicinal oil;
the plaster is prepared by the following steps: heating 30 parts of Vaseline to 80 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 12 parts of medical zinc oxide powder while stirring, naturally cooling to 60 ℃, adding 2 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 5
Pretreatment of traditional Chinese medicine: taking 14 parts of angelica sinensis, 4 parts of coptis chinensis, 8 parts of safflower, 8 parts of myrrh, 8 parts of dragon's blood, 14 parts of frankincense, 8 parts of baical skullcap root, 8 parts of sanchi, 14 parts of calcined dragon's bone, 8 parts of red paeony root, 8 parts of rhizoma corydalis, 8 parts of golden flower, 12 parts of astragalus membranaceus, 8 parts of gardenia and 12 parts of mongolian snakegourd root, cleaning by ultrasonic, drying at 45 ℃, cutting each medicinal material after drying, and uniformly stirring to obtain a medicinal material mixture;
extracting medicinal oil: 50 parts of sesame oil are taken and poured into a container for heating to 240 ℃, then the mixture is put into the container, the mixture is firstly heated to 340 ℃ and is continuously stirred, the interior of the mixture is turned into brown, then the mixture is cooled to 140 ℃, and the mixture is fished out to obtain medicinal oil;
the plaster is prepared by the following steps: heating 50 parts of Vaseline to 90 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 12 parts of medical zinc oxide powder while stirring, naturally cooling to 70-60 ℃, adding 3 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 6
Pretreatment of traditional Chinese medicine: taking 12 parts of angelica sinensis, 5 parts of coptis chinensis, 8 parts of safflower, 8 parts of myrrh, 8 parts of dragon's blood, 12 parts of frankincense, 6 parts of baical skullcap root, 80 parts of sanchi, 12 parts of calcined dragon's bone, 6 parts of red paeony root, 6 parts of rhizoma corydalis, 5 parts of golden flower, 12 parts of astragalus root, 5 parts of gardenia and 10 parts of mongolian snakegourd root, cleaning by ultrasonic, drying at 30 ℃, cutting each medicinal material after drying, and stirring and mixing uniformly to obtain a medicinal material mixture;
extracting medicinal oil: 50 parts of sesame oil are taken and poured into a container for heating to 225 ℃, then the mixture is put into the container, the mixture is firstly heated to 300 ℃ and is continuously stirred, the interior of the mixture is turned into brown, then the mixture is cooled to 100 ℃, and the mixture is fished out to obtain medicinal oil;
the plaster is prepared by the following steps: heating 50 parts of Vaseline to 80 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 10 parts of medical zinc oxide powder while stirring, naturally cooling to 60 ℃, adding 3 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Example 7
Pretreatment of traditional Chinese medicine: 10 parts of Chinese angelica, 5 parts of coptis chinensis, 8 parts of safflower, 8 parts of myrrh, 8 parts of dragon's blood, 10 parts of frankincense, 8 parts of baical skullcap root, 10 parts of sanchi, 12 parts of calcined dragon's bone, 8 parts of red paeony root, 5 parts of rhizoma corydalis, 6 parts of golden flower, 12 parts of astragalus root, 8 parts of gardenia and 10 parts of mongolian snakegourd root are cleaned by ultrasonic, and then dried at the temperature of 45 ℃, and each medicinal material is sheared after being dried, stirred and mixed uniformly to obtain a medicinal material mixture;
extracting medicinal oil: 50 parts of sesame oil are taken and poured into a container for heating to 200 ℃, then the mixture is put into the container, the mixture is firstly heated to 320 ℃ and is continuously stirred, the interior of the mixture is turned into brown, then the mixture is cooled to 100 ℃, and the mixture is fished out to obtain medicinal oil;
the plaster is prepared by the following steps: heating 50 parts of Vaseline to 85 ℃ for melting and heat preservation, adding the medicinal oil while stirring, adding 10 parts of medical zinc oxide powder while stirring, naturally cooling to 70-60 ℃, adding 3 parts of borneol while stirring, and fully and uniformly mixing to obtain the plaster.
Clinical test example
Clinical tests are carried out on the wound repair paste provided by the application in 2019, 12 months and 2020, 7 months, and the following are part of specific clinical test drug effect tracking conditions:
wu Mou when a man is 25 years old, the man falls down carelessly during riding, the knee and elbow are wounded in a large area, the skin on the knee and elbow is damaged and bleeding, after the wound is disinfected and cleaned, the wound repair paste provided by the application is coated twice a day, and the wound is completely healed after 7 days without scars.
Li Mou when a man is 13 years old, the man carelessly knocks down the thermos bottle during playing, the lower leg part is scalded, the injury is red and swollen, blisters appear, after the wound is disinfected and cleaned, the wound repair paste provided by the application is coated twice a day, and the wound is completely healed after 10 days without scars.
Zhang Mou when a man goes downstairs, the man slips carelessly, the muscles of the wrists of the right foot are pulled, the wounds of the right knee are damaged and bleeding on the surface skin, after the wounds are disinfected and cleaned, the wound repair paste provided by the application is coated, the elbows of the knee are wound in a large area, the damaged and bleeding on the surface skin is carried out, after the wounds are disinfected and cleaned, the wound repair paste provided by the application is coated, the wound repair paste is coated twice a day, and after 7 days, the wound of the right knee is completely healed without leaving scars; after 1 month, the ankle of the right foot is completely recovered to be normal.
Sun Mou when a woman ages 27 years old, the hot water kettle is placed aside by carelessly touching the woman, the left hand arm is scalded, the wound is red and swollen and blisters appear, the wound is disinfected and cleaned, and then the wound repair paste provided by the application is smeared, and the wound is completely healed after 14 days without scars.
Qian Mou after a man, 26 years old, the man carelessly steps on the three plugs pulled aside in the bathroom, the right heel is wound by the plugs and bleeds, the right ankle is pulled to be red and swollen, the wound is disinfected and cleaned, the wound repair paste provided by the application is smeared, the wound at the right heel is completely healed after 7 days, no scar is left, and the right ankle is completely recovered to be normal after 1 month.
Wu Mou after a man, 12 years old, the right foot is rolled into a bicycle wheel, the foot is red and swelling, the skin is damaged and bleeding, and the wound is disinfected and cleaned, the wound repair paste provided by the application is smeared, the wound is completely healed after 7 days, and the foot is recovered to be normal without scars.
Li Mou, female, 21 years old, right arm is carelessly injured by smashing by the carton box with the heavy object, right arm is red and swollen and is silted, after the wound is disinfected and cleaned, right arm is completely recovered to be normal after 5 days by using the wound repair paste provided by the application, and no trace is left.
Zhang Mou after men, 32 years old, the left hand is broken by mechanical parts, the wound bleeds and is locally red and swollen, and the wound is disinfected and cleaned, the wound repair paste provided by the application is completely recovered to be normal after 7 days, and no scar is left.
Huang Mou when a man ages 28 years, the right arm is scalded by oil, the wound is red and swollen and blisters appear, and after the wound is disinfected and cleaned, the wound repair paste provided by the application is used for completely recovering the normal state after 14 days, and no scar is left.
Li Mou A, 24 years old men, carelessly falling and sliding on the groove, and having red swelling and damage on a plurality of parts of the whole body, and after disinfecting and cleaning the wound, the wound repairing paste provided by the application is used for completely recovering the normal state after 20 days without leaving scars.
The wound repair paste provided by the application can treat and repair various wounds which are difficult to heal, has the effects of detumescence, stasis removal, hemostasis, pain relief, blood circulation activation and granulation promotion, and is convenient to use and store.
In summary, the wound repair paste provided by the embodiment of the application has the advantages that the paste is mainly prepared from traditional Chinese medicines, and the baikal skullcap root and the golden flower can dispel wind and remove dampness; safflower, myrrh, dragon's blood, frankincense, pseudo-ginseng, red paeony root and element Hu Bingpian can reduce swelling and remove blood stasis; the other medicinal materials can also stop bleeding, relieve pain, promote blood circulation and promote tissue regeneration; the medicines are matched and combined mutually, so that various wounds which are difficult to heal can be treated and repaired, the effect is good, the use is convenient, and the storage is easy; the method comprises the steps of firstly cleaning and drying angelica sinensis, coptis chinensis, safflower, myrrh, dragon's blood, frankincense, scutellaria baicalensis, pseudo-ginseng, calcined dragon's bone, red paeony root, rhizoma corydalis, golden flower, astragalus root, gardenia and radix trichosanthis through the pretreatment steps of the traditional Chinese medicines, removing impurities attached to the medicinal materials, helping to promote the efficacy, shearing and uniformly mixing to prepare medicinal material mixtures, fully mixing the medicinal materials, then putting the medicinal material mixtures into sesame oil through the extraction steps of the medicinal oil, stir-frying and refining to obtain the medicinal oil, fully extracting the effective components in each medicinal material, and adding the medicinal oil into Vaseline through the preparation steps of the plaster, respectively adding medical zinc oxide powder and borneol, stirring and uniformly mixing to prepare the plaster, further improving the efficacy of the medicinal materials, and being convenient to use and convenient to store. By the method, the effective components in the medicinal materials can be fully extracted, the medicinal materials are matched with each other, the medicinal effect can be better improved, and meanwhile, the comfort level in use can be enhanced.
The embodiments described above are some, but not all embodiments of the application. The detailed description of the embodiments of the application is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by those skilled in the art based on the embodiments of the application without making any inventive effort, are intended to be within the scope of the application.

Claims (4)

1. The wound repair paste is characterized by being prepared from the following raw materials in parts by weight: 10 parts of Chinese angelica, 5 parts of coptis chinensis, 8 parts of safflower, 8 parts of myrrh, 8 parts of dragon's blood, 10 parts of frankincense, 8 parts of baical skullcap root, 10 parts of sanchi, 12 parts of calcined dragon bone, 8 parts of red paeony root, 5 parts of rhizoma corydalis, 6 parts of golden flower tree, 12 parts of astragalus root, 8 parts of gardenia, 10 parts of mongolian snakegourd root, 3 parts of borneol, 10 parts of medical zinc oxide powder, 50 parts of sesame oil and 50 parts of vaseline;
the preparation method of the wound repair paste comprises the following steps:
pretreatment of traditional Chinese medicine: cleaning radix Angelicae sinensis, coptidis rhizoma, carthami flos, myrrha, sanguis Draxonis, olibanum, scutellariae radix, notoginseng radix, os Draconis preparata, radix Paeoniae Rubra, rhizoma corydalis, jin Huashu, radix astragali, fructus Gardeniae, and Trichosanthis radix by ultrasonic, drying, cutting, and stirring to obtain medicinal material mixture;
extracting medicinal oil: pouring sesame oil into a container for heating, then placing the medical material mixture, heating and stirring the medical material mixture continuously to make the interior of the medical material mixture be brown, then cooling the medical material mixture, and fishing out the medical material mixture to obtain medical oil;
the plaster is prepared by the following steps: heating, melting and preserving the heat of Vaseline, adding the medicinal oil while stirring, adding medical zinc oxide powder while stirring, naturally cooling, adding borneol while stirring, and fully and uniformly mixing to obtain the plaster;
in the step of pretreatment of the traditional Chinese medicine, the drying temperature is 30-50 ℃;
in the step of extracting the medicinal oil, the sesame oil is poured into a container to be heated to 200-250 ℃, then the medicinal material mixture is put into the container, the mixture is firstly heated to 300-350 ℃ and is continuously stirred to make the interior of the medicinal material mixture be brown, then the temperature of the medicinal material mixture is reduced to 150-100 ℃, and the medicinal material mixture is fished out to obtain the medicinal oil;
in the plaster preparation step, vaseline is heated to 80-90 ℃ for melting and heat preservation, then the medicinal oil is added while stirring, medical zinc oxide powder is added while stirring, the medical zinc oxide powder is naturally cooled, and borneol is added while stirring after cooling to 70-60 ℃, and the plaster is prepared after fully and uniformly mixing.
2. The wound healing paste according to claim 1, wherein in the step of pretreatment of the traditional Chinese medicine, the drying temperature is 45 ℃.
3. The wound healing ointment according to claim 1, wherein in the step of extracting the medicinal oil, sesame oil is poured into a container to be heated to 200 ℃, then the medicinal oil is put into the container, the mixture is heated to 320 ℃ and is continuously stirred, the interior of the medicinal oil mixture turns brown, the temperature of the medicinal oil is reduced to 100 ℃, and the medicinal oil is obtained by fishing out the medicinal oil mixture.
4. The wound healing ointment according to claim 1, wherein in the preparation step of the ointment, vaseline is heated to 85 ℃ for melting and heat preservation, then the medicinal oil is added while stirring, then medical zinc oxide powder is added while stirring, the medicinal oil is naturally cooled, and then borneol is added while stirring after cooling to 60 ℃ to obtain the ointment.
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1969996A (en) * 2006-10-01 2007-05-30 刘运磊 Chinese medicinal powder having functions in stopping bleeding, relieving pain, diminishing swelling and promoting granulation and preparation process thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1969996A (en) * 2006-10-01 2007-05-30 刘运磊 Chinese medicinal powder having functions in stopping bleeding, relieving pain, diminishing swelling and promoting granulation and preparation process thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
活血消肿纱条配合无菌包扎治疗四肢II度烧烫伤的疗效观察及护理;赵晓青等;《首都医药》;20021231(第2期);第60页,尤其是左栏第1、3段 *

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