CN111905167A - A multistage hemodialysis and blood component separation device - Google Patents
A multistage hemodialysis and blood component separation device Download PDFInfo
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- 238000000926 separation method Methods 0.000 title claims abstract description 26
- 239000012503 blood component Substances 0.000 title claims abstract description 21
- 238000001631 haemodialysis Methods 0.000 title claims abstract description 16
- 230000000322 hemodialysis Effects 0.000 title claims abstract description 16
- 239000008280 blood Substances 0.000 claims abstract description 73
- 210000004369 blood Anatomy 0.000 claims abstract description 73
- 239000012528 membrane Substances 0.000 claims abstract description 39
- 238000000502 dialysis Methods 0.000 claims abstract description 27
- 238000011026 diafiltration Methods 0.000 claims abstract description 4
- 230000003247 decreasing effect Effects 0.000 claims abstract description 3
- 238000009434 installation Methods 0.000 claims description 6
- 238000009413 insulation Methods 0.000 claims description 5
- 229920002678 cellulose Polymers 0.000 claims description 3
- 239000001913 cellulose Substances 0.000 claims description 3
- 238000001514 detection method Methods 0.000 abstract description 3
- 238000001914 filtration Methods 0.000 abstract description 3
- 238000011282 treatment Methods 0.000 description 7
- 230000005484 gravity Effects 0.000 description 6
- 238000012360 testing method Methods 0.000 description 4
- 239000000306 component Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 208000009304 Acute Kidney Injury Diseases 0.000 description 1
- 208000033626 Renal failure acute Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 201000011040 acute kidney failure Diseases 0.000 description 1
- 208000012998 acute renal failure Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000012959 renal replacement therapy Methods 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1631—Constructional aspects thereof having non-tubular membranes, e.g. sheets
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
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- Anesthesiology (AREA)
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Abstract
本发明涉及血液处理检测设备技术领域,公开了一种多级血液透析及血液成分分离装置,包括框架、血液进口、透析器、血液出口管道、过滤腔;框架的内部上侧通过左右侧的连接杆固定安装有呈S型结构的透析器,所述透析器的内部等间隔固定安装有多组用于对血液进行透析过滤的透析膜,所述血液出口管道的底部通过转动安装阀转动连通有一组呈球形结构的细胞过滤器,所述细胞过滤器的底部转动连接有旋转座,旋转座的中部向下连通有底部固定在地面上的过滤腔,所述细胞过滤器的内部固定安装有一圈离心网,所述过滤腔的内部自上而下等间隔固定安装有多组膜径依次减小的过滤膜。本发明的优点是:多级透析,准确度高,离心加多级过滤,分离精度高。
The invention relates to the technical field of blood processing and detection equipment, and discloses a multi-stage hemodialysis and blood component separation device, comprising a frame, a blood inlet, a dialyzer, a blood outlet pipe, and a filter cavity; the inner upper side of the frame is connected by the left and right sides. A dialyzer with an S-shaped structure is fixedly installed on the rod, and a plurality of groups of dialysis membranes for diafiltration of blood are fixedly installed inside the dialyzer at equal intervals. A set of cell strainers with spherical structure, the bottom of the cell strainer is rotatably connected with a rotating seat, the middle of the rotating seat is downwardly connected with a filter cavity whose bottom is fixed on the ground, and a ring is fixedly installed inside the cell strainer Centrifugal net, a plurality of groups of filter membranes with successively decreasing membrane diameters are fixedly installed inside the filter cavity at equal intervals from top to bottom. The advantages of the invention are: multi-stage dialysis, high accuracy, centrifugal and multi-stage filtration, high separation precision.
Description
技术领域technical field
本发明涉及血液处理检测设备技术领域,具体是一种多级血液透析及血液成分分离装置。The invention relates to the technical field of blood processing detection equipment, in particular to a multi-stage hemodialysis and blood component separation device.
背景技术Background technique
血液透析是急慢性肾功能衰竭患者肾脏替代治疗方式之一。一般来说在读血液进行透析前,需要对预测试处理,先取血液样品对其进行透析,然后检测该透析的具体效果如何,然后在通过判断是否将其应用与患者身上。Hemodialysis is one of the ways of renal replacement therapy for patients with acute and chronic renal failure. Generally speaking, before reading blood for dialysis, it is necessary to perform pre-test processing, first take blood samples for dialysis, and then check the specific effect of the dialysis, and then judge whether to apply it to the patient.
一般在对血液进行透析后,为了充分了解透析后血液的成分发生了何种变化,是否有杂质的进入或者是否有某种细胞或者成分丢失,需要对血液进行分离处理检测,因此就会用到血液成分分离装置,但是现有的装置多数是将血液的透析与成分分离分开进行,如此一来,不利于该血液检测的快速进行,工作效率低。Generally, after dialysis of blood, in order to fully understand what changes have occurred in the components of blood after dialysis, whether there are impurities entering or whether certain cells or components are lost, it is necessary to separate and process the blood for detection, so it is necessary to use For blood component separation devices, most of the existing devices separate blood dialysis and component separation, which is not conducive to rapid blood testing and low work efficiency.
发明内容SUMMARY OF THE INVENTION
本发明的目的在于提供一种多级血液透析及血液成分分离装置,以解决上述背景技术中提出的问题。The purpose of the present invention is to provide a multi-stage hemodialysis and blood component separation device to solve the above-mentioned problems in the background art.
为实现上述目的,本发明提供如下技术方案:一种多级血液透析及血液成分分离装置,包括框架、血液进口、透析器、血液出口管道、过滤腔;所述框架设置为下部开口的中空结构,框架的内部上侧通过左右侧的连接杆固定安装有呈S型结构的透析器,所述透析器的顶部左侧向上连通有端部置于框架外顶部的血液进口,通过血液进口将待处理的血液输入到透析器中进行透析,所述透析器的内部等间隔固定安装有多组用于对血液进行透析过滤的透析膜,通过将透析器设置为多级的S型结构,可将输入其内部的血液在重力的作用下,多次经过透析膜进行多级透析处理。位于最下侧透析器的底部左右两侧对称向下连通有血液出口,血液出口的底部连通有血液出口管道,所述血液出口管道的底部通过转动安装阀转动连通有一组呈球形结构的细胞过滤器,所述细胞过滤器的底部转动连接有旋转座,旋转座的中部向下连通有底部固定在地面上的过滤腔,细胞过滤器的旋转便于将输入到其内的血液进行离心处理,所述细胞过滤器的内部固定安装有一圈离心网,通过离心网以及细胞过滤器的旋转便于将血液中的细胞与血浆相互分离,离心后的血液在重力的左右下落入到过滤腔的内部,进入到离心网与细胞过滤器内壁之间区域的血液的成分,可通过设置在细胞过滤器外侧壁下部的输料口输出。所述过滤腔的内部自上而下等间隔固定安装有多组膜径依次减小的过滤膜,所述过滤膜的左右两侧向外连通有固定在过滤腔外侧壁上的血袋,通过过滤膜的过滤然后残留在过滤膜上的血液成分沿着过滤膜流入到血袋中,从而实现分离。In order to achieve the above purpose, the present invention provides the following technical solutions: a multi-stage hemodialysis and blood component separation device, comprising a frame, a blood inlet, a dialyzer, a blood outlet pipe, and a filter cavity; the frame is provided as a hollow structure with an opening at the bottom. The inner upper side of the frame is fixedly installed with a dialyzer with an S-shaped structure through the connecting rods on the left and right sides. The treated blood is input into the dialyzer for dialysis, and a plurality of sets of dialysis membranes for diafiltration of blood are fixedly installed inside the dialyzer at equal intervals. Under the action of gravity, the blood inputted into it passes through the dialysis membrane for many times for multi-stage dialysis treatment. The bottom of the dialyzer on the lowermost side is symmetrically connected with the blood outlet on the left and right sides, the bottom of the blood outlet is connected with the blood outlet pipeline, and the bottom of the blood outlet pipeline is connected with a group of spherical structure cell filter by rotating the installation valve. The bottom of the cell filter is rotatably connected with a rotating seat, and the middle of the rotating seat is connected downward with a filter cavity whose bottom is fixed on the ground. The rotation of the cell filter is convenient for centrifuging the blood input into it. The inside of the cell strainer is fixedly installed with a circle of centrifugal nets, and the rotation of the centrifugal net and the cell strainer facilitates the separation of cells and plasma in the blood. The blood components in the area between the centrifugal net and the inner wall of the cell strainer can be output through the delivery port provided at the lower part of the outer side wall of the cell strainer. The interior of the filter cavity is fixedly installed with a plurality of groups of filter membranes with decreasing membrane diameters from top to bottom at equal intervals. The left and right sides of the filter membrane are connected to the outside with blood bags fixed on the outer wall of the filter cavity. Filtration of the filter membrane Then the blood components remaining on the filter membrane flow into the blood bag along the filter membrane, thereby achieving separation.
作为本发明进一步的方案:透析膜为半透膜且由纤维素膜或者合成膜制成。As a further solution of the present invention: the dialysis membrane is a semi-permeable membrane and is made of a cellulose membrane or a synthetic membrane.
作为本发明进一步的方案:所述细胞过滤器的顶部一圈固定安装有从动齿,从动齿的远离框架竖直中心线的一侧啮合有主动齿,主动齿的顶部向上通过转动轴转动连接有通过安装板固定在框架内壁上的伺服电机,通过启动伺服电机驱动主动齿旋转,从而带动从动齿下侧的细胞过滤器进行转动。As a further solution of the present invention: the top of the cell filter is fixedly installed with driven teeth, the side of the driven teeth away from the vertical centerline of the frame is engaged with driving teeth, and the top of the driving teeth is rotated upward through the rotating shaft A servo motor fixed on the inner wall of the frame through the mounting plate is connected, and the driving tooth is driven to rotate by starting the servo motor, thereby driving the cell filter under the driven tooth to rotate.
作为本发明进一步的方案:血袋与过滤腔的连通处设置有控制阀。As a further solution of the present invention, a control valve is arranged at the communication between the blood bag and the filter cavity.
作为本发明再进一步的方案:所述血袋的外部包裹有一层保温层,用于对输入到血袋内部的血液进行保温处理,防止因温度过高或者过低影响收集的血液成分的活性,从而影响后续检测的结果。As a further solution of the present invention: the outside of the blood bag is wrapped with a layer of thermal insulation layer, which is used for thermal insulation treatment of the blood input into the blood bag, so as to prevent the activity of the collected blood components from being affected by the temperature being too high or too low, This affects the results of subsequent tests.
与现有技术相比,本发明的有益效果是:通过将血液经过呈S型结构的透析器的内部,然后在重力的作用下,经过多组透析膜进行透析处理,从而实现多级透析操作;通过在透析器的底部左右两侧向下设置两组细胞过滤器以及过滤腔,从而实现对血液的快速处分离处理;通过将血液先经过细胞过滤器内部进行离心,然后在依次经过多组过滤膜,从而便于对透析后的血液进行精准的分离;通过将细胞过滤器的顶部通过转动安装阀与血液出口管道的转动连通的方式进行连接,便于血液透析与分离装置的安拆;本发明的优点是:多级透析,准确度高,离心加多级过滤,分离精度高。Compared with the prior art, the beneficial effect of the present invention is: by passing the blood through the inside of the dialyzer with the S-shaped structure, and then under the action of gravity, the dialysis treatment is carried out through multiple groups of dialysis membranes, thereby realizing multi-stage dialysis operation. ; By setting two groups of cell filters and filter chambers downward on the bottom left and right sides of the dialyzer, the rapid separation and treatment of blood can be achieved; by first centrifuging the blood through the inside of the cell filter, and then passing through multiple groups of cells in turn. filter membrane, so as to facilitate accurate separation of the blood after dialysis; by connecting the top of the cell filter with the rotation of the blood outlet pipe through the rotating installation valve, it is convenient for the installation and disassembly of the hemodialysis and separation device; the present invention The advantages are: multi-stage dialysis, high accuracy, centrifugal plus multi-stage filtration, high separation accuracy.
附图说明Description of drawings
图1为一种多级血液透析及血液成分分离装置的结构示意图。FIG. 1 is a schematic structural diagram of a multi-stage hemodialysis and blood component separation device.
图2为一种多级血液透析及血液成分分离装置中透析器的结构示意图。FIG. 2 is a schematic structural diagram of a dialyzer in a multistage hemodialysis and blood component separation device.
图3为一种多级血液透析及血液成分分离装置中细胞过滤器的俯视结构示意图。3 is a schematic top view of a cell filter in a multi-stage hemodialysis and blood component separation device.
其中:框架10,血液进口11,转动安装阀12,透析器13,透析膜14,血液出口15,细胞过滤器16,从动齿17,主动齿18,伺服电机19,血液出口管道20,离心网21,过滤腔22,过滤膜23,血袋24,旋转座25。Among them:
具体实施方式Detailed ways
下面结合具体实施方式对本专利的技术方案作进一步详细地说明。The technical solution of the present patent will be described in further detail below in conjunction with specific embodiments.
实施例一Example 1
请参阅图1-3,一种多级血液透析及血液成分分离装置,包括框架10、血液进口11、透析器13、血液出口管道20、过滤腔22;所述框架10设置为下部开口的中空结构,框架10的内部上侧通过左右侧的连接杆固定安装有呈S型结构的透析器13,所述透析器13的顶部左侧向上连通有端部置于框架10外顶部的血液进口11,通过血液进口11将待处理的血液输入到透析器13中进行透析,所述透析器13的内部等间隔固定安装有多组用于对血液进行透析过滤的透析膜14,透析膜14为半透膜且由纤维素膜或者合成膜制成,通过将透析器13设置为多级的S型结构,可将输入其内部的血液在重力的作用下,多次经过透析膜14进行多级透析处理。位于最下侧透析器13的底部左右两侧对称向下连通有血液出口15,血液出口15的底部连通有血液出口管道20,所述血液出口管道20的底部通过转动安装阀12转动连通有一组呈球形结构的细胞过滤器16,所述细胞过滤器16的顶部一圈固定安装有从动齿17,从动齿17的远离框架10竖直中心线的一侧啮合有主动齿18,主动齿18的顶部向上通过转动轴转动连接有通过安装板固定在框架10内壁上的伺服电机19,通过启动伺服电机19驱动主动齿18旋转,从而带动从动齿17下侧的细胞过滤器16进行转动,所述细胞过滤器16的底部转动连接有旋转座25,旋转座25的中部向下连通有底部固定在地面上的过滤腔22,细胞过滤器16的旋转便于将输入到其内的血液进行离心处理,所述细胞过滤器16的内部固定安装有一圈离心网21,通过离心网21以及细胞过滤器16的旋转便于将血液中的细胞与血浆相互分离,离心后的血液在重力的左右下落入到过滤腔22的内部,进入到离心网21与细胞过滤器16内壁之间区域的血液的成分,可通过设置在细胞过滤器16外侧壁下部的输料口输出。所述过滤腔22的内部自上而下等间隔固定安装有多组膜径依次减小的过滤膜23,所述过滤膜23的左右两侧向外连通有固定在过滤腔22外侧壁上的血袋24,血袋24与过滤腔22的连通处设置有控制阀,通过过滤膜23的过滤然后残留在过滤膜23上的血液成分沿着过滤膜23流入到血袋24中,从而实现分离。1-3, a multi-stage hemodialysis and blood component separation device includes a
实施例二Embodiment 2
在实施例一的基础上,所述血袋24的外部包裹有一层保温层,用于对输入到血袋24内部的血液进行保温处理,防止因温度过高或者过低影响收集的血液成分的活性,从而影响后续检测的结果。On the basis of the first embodiment, the outside of the
本发明的工作原理是:使用时,首先将待处理的血液经过血液进口11输入到透析器13中在重力的作用下,分别经过多组透析膜14将其进行充分的透析处理,然后通过底部左右两侧的血液出口15将透析后的血液输入到细胞过滤器16中进行离心处理,经过离心网21进行相互分离,然后离心后的血液在重力的作用下,落入到过滤腔22中,然后通过多组过滤膜23对其进行多级过滤,从而便于将血液进行精准的分离。The working principle of the present invention is as follows: when in use, the blood to be treated is firstly input into the
上面对本专利的较佳实施方式作了详细说明,但是本专利并不限于上述实施方式,在本领域的普通技术人员所具备的知识范围内,还可以在不脱离本专利宗旨的前提下做出各种变化。The preferred embodiments of the present patent have been described in detail above, but the present patent is not limited to the above-mentioned embodiments. Within the scope of knowledge possessed by those of ordinary skill in the art, the present invention can also be made without departing from the purpose of the present patent. Various changes.
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CN202010698328.0A Pending CN111905167A (en) | 2020-07-20 | 2020-07-20 | A multistage hemodialysis and blood component separation device |
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EP0371178A1 (en) * | 1988-12-01 | 1990-06-06 | Tokyo Bi-Tech Laboratories Inc | Method for producing a blood cleaning apparatus with hollow fiber membranes |
CN202554465U (en) * | 2012-05-13 | 2012-11-28 | 刘勇峰 | Enterocoelia autoblood collection filter bag |
CN203252974U (en) * | 2013-05-08 | 2013-10-30 | 四川南格尔生物医学股份有限公司 | Membrane-filtering type plasma separation cup |
CN108310503A (en) * | 2018-02-08 | 2018-07-24 | 中南大学湘雅二医院 | A kind of Almightiness type plasma purification system based on centrifugal separation plasma method |
KR20190117377A (en) * | 2018-04-06 | 2019-10-16 | 광운대학교 산학협력단 | Microwave treatment apparatus and method for blood cancer therapy |
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EP0371178A1 (en) * | 1988-12-01 | 1990-06-06 | Tokyo Bi-Tech Laboratories Inc | Method for producing a blood cleaning apparatus with hollow fiber membranes |
CN202554465U (en) * | 2012-05-13 | 2012-11-28 | 刘勇峰 | Enterocoelia autoblood collection filter bag |
CN203252974U (en) * | 2013-05-08 | 2013-10-30 | 四川南格尔生物医学股份有限公司 | Membrane-filtering type plasma separation cup |
CN108310503A (en) * | 2018-02-08 | 2018-07-24 | 中南大学湘雅二医院 | A kind of Almightiness type plasma purification system based on centrifugal separation plasma method |
KR20190117377A (en) * | 2018-04-06 | 2019-10-16 | 광운대학교 산학협력단 | Microwave treatment apparatus and method for blood cancer therapy |
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Application publication date: 20201110 |