CN111904613A - Puncture positioning grid for image guidance - Google Patents
Puncture positioning grid for image guidance Download PDFInfo
- Publication number
- CN111904613A CN111904613A CN202010874634.5A CN202010874634A CN111904613A CN 111904613 A CN111904613 A CN 111904613A CN 202010874634 A CN202010874634 A CN 202010874634A CN 111904613 A CN111904613 A CN 111904613A
- Authority
- CN
- China
- Prior art keywords
- grid
- base layer
- substrate base
- image guidance
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000758 substrate Substances 0.000 claims abstract description 32
- 229910052751 metal Inorganic materials 0.000 claims abstract description 9
- 239000002184 metal Substances 0.000 claims abstract description 9
- 230000002745 absorbent Effects 0.000 claims abstract description 5
- 239000002250 absorbent Substances 0.000 claims abstract description 5
- 239000004745 nonwoven fabric Substances 0.000 claims abstract description 4
- 150000002736 metal compounds Chemical class 0.000 claims description 9
- 230000005298 paramagnetic effect Effects 0.000 claims description 7
- 239000000126 substance Substances 0.000 claims description 7
- 239000003550 marker Substances 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 150000002739 metals Chemical class 0.000 claims description 4
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims description 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims description 3
- 239000002872 contrast media Substances 0.000 claims description 3
- 229910052740 iodine Inorganic materials 0.000 claims description 3
- 239000011630 iodine Substances 0.000 claims description 3
- 239000011159 matrix material Substances 0.000 claims description 3
- ONALOACLIWHNGJ-VPVMAENOSA-N 2-[bis[2-[bis(carboxymethyl)amino]ethyl]amino]acetic acid;gadolinium;(2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentol Chemical group [Gd].CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O ONALOACLIWHNGJ-VPVMAENOSA-N 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 206010011409 Cross infection Diseases 0.000 abstract description 4
- 229910052688 Gadolinium Inorganic materials 0.000 abstract description 4
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 4
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 abstract description 4
- 238000004519 manufacturing process Methods 0.000 abstract description 4
- 238000001179 sorption measurement Methods 0.000 abstract description 3
- 239000000843 powder Substances 0.000 abstract description 2
- 150000002632 lipids Chemical class 0.000 abstract 1
- 238000002595 magnetic resonance imaging Methods 0.000 description 9
- 150000003626 triacylglycerols Chemical class 0.000 description 3
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 description 2
- 230000005291 magnetic effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- QPCDCPDFJACHGM-UHFFFAOYSA-N N,N-bis{2-[bis(carboxymethyl)amino]ethyl}glycine Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(=O)O)CCN(CC(O)=O)CC(O)=O QPCDCPDFJACHGM-UHFFFAOYSA-N 0.000 description 1
- MBBZMMPHUWSWHV-BDVNFPICSA-N N-methylglucamine Chemical compound CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO MBBZMMPHUWSWHV-BDVNFPICSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 238000010317 ablation therapy Methods 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 238000013170 computed tomography imaging Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000004519 grease Substances 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229960003194 meglumine Drugs 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000013188 needle biopsy Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229940067082 pentetate Drugs 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/34—Trocars; Puncturing needles
- A61B17/3403—Needle locating or guiding means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3954—Markers, e.g. radio-opaque or breast lesions markers magnetic, e.g. NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3966—Radiopaque markers visible in an X-ray image
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
- A61B2090/3983—Reference marker arrangements for use with image guided surgery
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
本发明公开了一种用于影像引导的穿刺定位格栅，其特征在于：包括承印物基层，在承印物基层上设置有多个用于CT以及MRI显影的栅条，所述所述承印物基层由较高吸附性的且柔性的薄半透明水溶性转印纸或半透明无纺布制成制成；所述栅条的主要组分包括高密度金属粉末、钆、脂质以及油性彩色溶液基质，格栅通过印制的方式的设置在承印物基层表面。栅条在吸附性强的柔性基质上印制方便，能够同时在CT和MRI显影的，制作成本低，可以作为一次性用品，减少了交叉感染。
The invention discloses a puncture positioning grid for image guidance, which is characterized by comprising a substrate base layer, and a plurality of grid bars for CT and MRI development are arranged on the substrate base layer. The base layer is made of highly absorbent and flexible thin translucent water-soluble transfer paper or translucent non-woven fabric; the main components of the grid include high-density metal powder, gadolinium, lipid and oily color For the solution substrate, the grid is arranged on the surface of the substrate base layer by printing. The grid bars can be easily printed on a flexible substrate with strong adsorption, can be developed in CT and MRI at the same time, have low manufacturing cost, can be used as disposable products, and reduce cross-infection.
Description
技术领域technical field
本发明涉及临床穿刺定位技术，具体涉及一种用于影像引导的穿刺定位格栅。The invention relates to a clinical puncture positioning technology, in particular to a puncture positioning grid used for image guidance.
背景技术Background technique
影像学，包括CT和MRI，由于其空间分辨率高，无骨和空气的伪影干扰，因此被广泛应用于各种经皮穿刺操作的影像引导工具，例如穿刺活检、脓肿引流及各种肿瘤消融治疗等。尽管根据CT和MRI断层图像所在的床面位置，可以选择穿刺病灶的最佳层面，但无法确定穿刺点的准确物理位置。因此往往需要在扫描前，在穿刺区域的体表放置定位格栅，以便精确定位穿刺针的入针点。Imaging, including CT and MRI, is widely used in image-guided tools for various percutaneous procedures, such as needle biopsy, abscess drainage, and various tumors, due to its high spatial resolution and absence of bone and air artifacts. ablation therapy, etc. Although the best slice of the puncture lesion can be selected according to the position of the bed surface on the CT and MRI tomographic images, the exact physical location of the puncture point cannot be determined. Therefore, it is often necessary to place a positioning grid on the body surface of the puncture area before scanning, so as to precisely locate the entry point of the puncture needle.
目前在临床使用的最广泛的定位格栅多由临床医生，用胶带平行黏贴多段金属丝(钢丝或介入用导丝)来制作。这种简易的定位格栅尽管价格便宜，但需要在穿刺前临时制作，非常耗时且不精确。专用的金属格栅价格非常昂贵，反复使用造成的不同患者之间的院内交叉感染的风险也大大提高，另外由于其采用硬质材料料，故与患者的皮肤贴合状况不好，导致确定穿刺点的时候出现位置的漂移，给后续的精准穿刺计算带来错误。另外这种采用金属材料制作的格栅仅仅能够在CT上使用，目前市场上尚缺乏能够在磁共振上使用的定位格栅，因为MRI和CT成像的技术原理完全不一样。The most widely used positioning grids currently used in clinics are mostly made by clinicians by sticking multiple segments of metal wires (steel wires or interventional guide wires) in parallel with tape. This simple positioning grid, although inexpensive, needs to be fabricated temporarily before puncturing, which is time-consuming and imprecise. The special metal grille is very expensive, and the risk of nosocomial cross-infection between different patients due to repeated use is also greatly increased. In addition, because it is made of hard material, it does not fit well with the patient's skin, which leads to the determination of puncture. The position drift occurs when the point is pressed, which brings errors to the subsequent accurate puncture calculation. In addition, this kind of grid made of metal material can only be used on CT. At present, there is no positioning grid that can be used on magnetic resonance imaging in the market, because the technical principles of MRI and CT imaging are completely different.
发明内容SUMMARY OF THE INVENTION
本发明要解决的技术问题是提供一种时兼容CT和MRI，且制作成本较低的用于影像引导的穿刺定位格栅。The technical problem to be solved by the present invention is to provide a puncture positioning grid for image guidance that is compatible with CT and MRI, and has a lower production cost.
为了解决上述技术问题，本发明采用的技术方案为：一种用于影像引导的穿刺定位格栅，包括承印物基层，在承印物基层上设置有多个用于CT以及MRI显影的栅条，所述承印物基层由柔性材料制成；所述栅条的主要组分包括高密度金属化合物、顺磁性物质、甘油三脂以及油性彩色溶液基质，其中高密度金属化合物、顺磁性物质、甘油三脂的质量比为3:0.8～1.2: 0.8～1.2，其中栅条通过印制的方式的设置在承印物基层表面；高密度金属指原子序数大于53 的金属。In order to solve the above-mentioned technical problems, the technical solution adopted in the present invention is: a puncture positioning grid for image guidance, comprising a substrate base layer, and a plurality of grid bars for CT and MRI development are arranged on the substrate base layer, The substrate base layer is made of flexible materials; the main components of the grid bars include high-density metal compounds, paramagnetic substances, triglycerides and oily color solution substrates, wherein high-density metal compounds, paramagnetic substances, triglycerides The mass ratio of the grease is 3:0.8-1.2:0.8-1.2, wherein the grid bars are arranged on the surface of the base layer of the substrate by printing; high-density metals refer to metals with an atomic number greater than 53.
进一步的，所述承印物基层采用具有吸附性的且柔性的薄半透明水溶性转印纸或半透明无纺布制成，油性记号笔的墨水可渗透承印物基层进入皮肤表面。Further, the substrate base layer is made of absorbent and flexible thin translucent water-soluble transfer paper or translucent non-woven fabric, and the ink of the oily marker can penetrate the substrate base layer and enter the skin surface.
进一步的，所述栅条中还混入有机碘造影剂。Further, organic iodine contrast agent is also mixed into the grid bars.
进一步的，所述顺磁性物质为钆喷替酸葡胺。Further, the paramagnetic substance is gadopentetate meglumine.
进一步的，所述承印物基层与皮肤接触的一面具有自粘性，可粘贴在皮肤表面。Further, the side of the substrate base layer in contact with the skin is self-adhesive and can be pasted on the surface of the skin.
从上述技术方案可以看出本发明具有以下优点：栅条在吸附性强的柔性基质上印制方便，能够同时在CT和MRI显影的，具有自粘性，能够良好的贴服在患者身体表面，降低标记点的漂移。制作成本低，因此可以作为一次性用品，减少了交叉感染。It can be seen from the above technical solutions that the present invention has the following advantages: the grid bars are easy to print on a flexible substrate with strong adsorption, can be developed in CT and MRI at the same time, have self-adhesion, and can be well adhered to the surface of the patient's body, Reduce marker drift. The production cost is low, so it can be used as a disposable product, reducing cross-infection.
附图说明Description of drawings
图1为本发明的结构示意图。FIG. 1 is a schematic structural diagram of the present invention.
具体实施方式Detailed ways
以下结合附图对本发明的具体实施方式做具体说明。The specific embodiments of the present invention will be described in detail below with reference to the accompanying drawings.
本发明的用于影像引导的穿刺定位格栅，包括承印物基层1。承印物基层采用具有吸附性的且柔性的薄半透明水溶性转印纸或半透明无纺布制成，油性记号笔的墨水可渗透承印物基层进入皮肤表面。柔性的基质可以承印物基层与皮肤贴合，将承印物基层粘贴在皮肤上，在确定穿刺点的时候不会出现位置偏移，可以对穿刺点进行精准计算。采用具有吸附性的基质，可以油性记号笔的墨水可渗透承印物基层进入皮肤表面，便于对穿刺点进行标记。The puncture positioning grid for image guidance of the present invention includes a substrate base layer 1 . The substrate base layer is made of absorbent and flexible thin translucent water-soluble transfer paper or translucent non-woven fabric, and the ink of the oily marker can penetrate the substrate base layer and enter the skin surface. The flexible substrate can fit the base layer of the substrate and the skin, and the base layer of the substrate can be pasted on the skin. When determining the puncture point, there will be no position deviation, and the puncture point can be accurately calculated. Using an absorbent substrate, the ink of the oil-based marker can penetrate the substrate base layer and enter the skin surface, which is convenient for marking the puncture point.
在承印物基层上设置有多个用于CT以及MRI显影的栅条2，其中每个栅条的主要组分包括高密度金属化合物粉末(或者高密度金属化合物溶剂)、钆(或者钆喷替酸葡胺)、甘油三脂以及油性彩色溶液基质，其中各成分的质量比为高密度金属化合物、顺磁性物质、甘油三脂的质量比为3:0.8～1.2:0.8～1.2，油性彩色溶液基质的量将上述材料均匀融入即可。其中高密度金属是指原子序数大于53的稳定高密度金属，高密度金属化合物能在CT上显影，高密度金属化合物可以采用硫酸钡。钆能够在磁共振T1WI上显影为高信号。甘油三脂在在磁共振T2上显影为高信号。A plurality of
将上述材料按照配比制成浆料作为栅条的原料，并通过印制的方式的打印在承印物基层表面形成栅条。The above-mentioned materials are made into paste according to the proportion as the raw material of the grid, and the grid is formed on the surface of the base layer of the substrate by printing.
此外，每个定位格栅还可以配置一次性消毒包装，可应用在无菌环境中。In addition, each positioning grid can also be equipped with disposable sterile packaging, which can be used in sterile environments.
此外，在栅条中还可以加入有几碘造影剂。In addition, several iodine contrast agents can be added to the grid bars.
栅条在吸附性强的柔性基质上印制方便，能够同时在CT和MRI显影的，具有自粘性，能够良好的贴服在患者身体表面，降低标记点的漂移。制作成本低，因此可以作为一次性用品，减少了交叉感染。The grid is convenient to print on a flexible substrate with strong adsorption, can be developed in CT and MRI at the same time, has self-adhesion, can be well adhered to the surface of the patient's body, and reduces the drift of the marking point. The production cost is low, so it can be used as a disposable product, reducing cross-infection.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010874634.5A CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010874634.5A CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111904613A true CN111904613A (en) | 2020-11-10 |
Family
ID=73278768
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202010874634.5A Pending CN111904613A (en) | 2020-08-27 | 2020-08-27 | Puncture positioning grid for image guidance |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN111904613A (en) |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5052035A (en) * | 1989-11-02 | 1991-09-24 | Webb Research Ii Corporation | Image location marking devices for radiographs, method of making and methods of use |
| CN102028550A (en) * | 2011-01-05 | 2011-04-27 | 武汉维斯第医用科技有限公司 | Clinical medicinal patch with developing coordinates |
| US20120163553A1 (en) * | 2010-12-27 | 2012-06-28 | Analogic Corporation | Three-dimensional metal printing |
| CN104114093A (en) * | 2011-12-08 | 2014-10-22 | 帕克实验室股份有限公司 | Biopsy grid |
| CN205458730U (en) * | 2016-01-27 | 2016-08-17 | 王小楠 | Low -cost medical ray location film |
| CN110664494A (en) * | 2019-09-25 | 2020-01-10 | 温州医科大学附属第一医院 | Ablation puncture auxiliary patch |
| CN110840573A (en) * | 2019-11-28 | 2020-02-28 | 徐州英杰医疗科技有限公司 | Contrast material, developing adhesive tape external positioning plaster and production process thereof |
| CN211213153U (en) * | 2019-12-10 | 2020-08-11 | 重庆市铜梁区人民医院 | Body surface positioning patch for nuclear magnetic resonance examination |
-
2020
- 2020-08-27 CN CN202010874634.5A patent/CN111904613A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5052035A (en) * | 1989-11-02 | 1991-09-24 | Webb Research Ii Corporation | Image location marking devices for radiographs, method of making and methods of use |
| US20120163553A1 (en) * | 2010-12-27 | 2012-06-28 | Analogic Corporation | Three-dimensional metal printing |
| CN102028550A (en) * | 2011-01-05 | 2011-04-27 | 武汉维斯第医用科技有限公司 | Clinical medicinal patch with developing coordinates |
| CN104114093A (en) * | 2011-12-08 | 2014-10-22 | 帕克实验室股份有限公司 | Biopsy grid |
| CN205458730U (en) * | 2016-01-27 | 2016-08-17 | 王小楠 | Low -cost medical ray location film |
| CN110664494A (en) * | 2019-09-25 | 2020-01-10 | 温州医科大学附属第一医院 | Ablation puncture auxiliary patch |
| CN110840573A (en) * | 2019-11-28 | 2020-02-28 | 徐州英杰医疗科技有限公司 | Contrast material, developing adhesive tape external positioning plaster and production process thereof |
| CN211213153U (en) * | 2019-12-10 | 2020-08-11 | 重庆市铜梁区人民医院 | Body surface positioning patch for nuclear magnetic resonance examination |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5368030A (en) | Non-invasive multi-modality radiographic surface markers | |
| US4860331A (en) | Image marker device | |
| US5260985A (en) | Conforming localization/biopsy grid and control apparatus | |
| US20120302863A1 (en) | Medical Procedure Localizing Aid | |
| US6419680B1 (en) | CT and MRI visible index markers for stereotactic localization | |
| US5469847A (en) | Radiographic multi-modality skin markers | |
| US6533794B2 (en) | Simplified stereotactic apparatus and methods | |
| US5848125A (en) | Radiopaque landmark skin markers and method | |
| CN109805990B (en) | Auxiliary positioning device and positioning system for puncture | |
| US10143531B2 (en) | Skin marking porous grid and related method of use | |
| US6406482B1 (en) | Stereotactic apparatus and methods | |
| EP1152706B1 (en) | Surgical navigation system having a marking device and a pointer for a tracking device | |
| CN210811389U (en) | Auxiliary positioning device and positioning system for puncture | |
| CN111904613A (en) | Puncture positioning grid for image guidance | |
| CN209611254U (en) | A CT-guided percutaneous lung biopsy positioning device | |
| CN111297446A (en) | Accurate positioning and fixing device for thoracocentesis | |
| CN209437378U (en) | Breast cancer sentinel lymph node body surface positioning patch and positioning set | |
| CN209595888U (en) | A magnetic resonance positioning device | |
| CN109363769B (en) | Magnetic resonance positioning device and positioning method | |
| CN211131427U (en) | CT guide puncture body surface positioning grid | |
| CN213787387U (en) | Magnetic resonance body surface positioning device | |
| Rousu et al. | COMPUTER-ASSISTED IMAGE-GUIDED SURGERY USING THE REGULUS™ NAVIGATOR | |
| Thomas et al. | In vitro assessment of needle artifacts with an interactive three-dimensional MR fluoroscopy system | |
| CN211962224U (en) | A device that facilitates the positioning of breast nodules | |
| CN222055518U (en) | CT positioning and developing device |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20201110 |
|
| RJ01 | Rejection of invention patent application after publication |