CN111803166B

CN111803166B - Occluder and occluder locking system

Info

Publication number: CN111803166B
Application number: CN201910291642.4A
Authority: CN
Inventors: 请求不公布姓名; 王永胜; 刘兴治
Original assignee: Hangzhou Wei Qiang Medical Technology Co ltd
Current assignee: Hangzhou Wei Qiang Medical Technology Co ltd
Priority date: 2019-04-11
Filing date: 2019-04-11
Publication date: 2025-09-12
Anticipated expiration: 2039-04-11
Also published as: CN111803166A

Abstract

The invention provides an occluder, which comprises a proximal end occluding part, wherein a first tightening member is arranged at the proximal end of the proximal end occluding part, a conical sliding guide structure is arranged at the periphery of the first tightening member at the proximal end occluding part, and the inner diameter of the sliding guide structure is gradually reduced from the distal end to the proximal end. The guide sliding structure has a guiding function, so that the plugging device is convenient to easily recover and enter the sheath tube. The invention also relates to an occluder locking system.

Description

Plugging device and plugging device locking system

Technical Field

The invention relates to the technical field of medical instruments, in particular to an occluder and an occluder locking system.

Background

The occluder is used as an implant for interventional therapy and is used for treating atrial septal defect, ventricular septal defect, patent arterial duct, and the like, and the existing occluder is divided into patent arterial duct occluder, atrial septal defect occluder, ventricular septal defect occluder, and the like. The basic structure of the arterial catheter non-closed plugging device is a mushroom-shaped device which is made of super-elastic nickel-titanium alloy, a macromolecule biological film is attached to the mushroom-shaped device, and polyester or polytetrafluoroethylene is filled in the net-shaped structure; the atrial septal defect plugging device and the ventricular septal defect plugging device are self-expanding double-disc structures formed by densely weaving nickel-titanium alloy wires, and an inner space of each disc structure is provided with an inner polymer flow blocking film. However, when the existing occluder is used in interventional operation, when the occluder is pulled to retract into the sheath, the proximal end face of the occluder is approximately flat, and the alloy wires are gathered at the end faces of the two ends, so that the two ends of the occluder are easy to bulge after being pulled, the stretched occluder is inconvenient to enter the sheath and push in the sheath, more importantly, when the occluder is not locked successfully, the occluder needs to be recovered, and because the occluder at the break of a lesion and an inner steel cable connected with the occluder are also slightly bent, the occluding part of the occluder is always propped against the side wall of the distal end port of the sheath during recovery, so that the recovery of the occluder is problematic, thereby reducing the operation efficiency and affecting the success rate of the operation.

Disclosure of Invention

The invention aims to solve the technical problem of providing an occluder convenient to use and an occluder locking device with the occluder aiming at the defects of the prior art.

In order to solve the technical problems, the invention provides an occluder, which comprises a proximal end occluding part, wherein a first tightening member is arranged at the proximal end of the proximal end occluding part, a conical sliding guide structure is arranged at the periphery of the first tightening member at the proximal end occluding part, and the inner diameter of the sliding guide structure is gradually reduced from the distal end to the proximal end.

The invention also provides a plugging device locking system, which comprises a sheath tube bending-adjustable device, a loader, a pushing device and a plugging device, wherein the sheath tube bending-adjustable device comprises a sheath tube, the loader comprises a loading tube, the distal end of the loading tube is inserted into the sheath tube, the pushing device comprises a pushing combination, the plugging device comprises a proximal plugging part, a first tightening member is arranged at the proximal end of the proximal plugging part, a conical sliding guide structure is arranged at the periphery of the first tightening member at the proximal plugging part, the inner diameter of the sliding guide structure is gradually reduced from the distal end to the proximal end, and the sliding guide structure has a guiding function, so that the plugging device can be conveniently recycled into the sheath tube by the pushing combination.

The proximal end of the proximal end blocking part of the plugging device is provided with the conical guide sliding structure at the periphery of the first tightening member, and when the plugging device needs to be recovered into the sheath tube, the plugging device can easily enter the sheath tube along the guide sliding structure due to the guide effect of the guide sliding structure, so that the plugging device is convenient to use.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

Fig. 1 is a schematic structural view of an occluder in accordance with one embodiment of the present invention.

Fig. 2 is a schematic cross-sectional view taken along line II-II in fig. 1.

Fig. 3 is an enlarged view of the connecting pin of fig. 2.

Fig. 4 is a top view of the connecting pin of fig. 2.

Fig. 5 is a schematic view of the construction of an occluder locking system provided with the occluder of fig. 1.

Fig. 6 is an exploded view of the occluder and push combination of fig. 5.

Fig. 7 is a schematic view of the distal end face structure of the push tube in the push combination of fig. 6.

Fig. 8 is a schematic cross-sectional view taken along line VIII-VIII in fig. 6.

Fig. 9 is a schematic cross-sectional view of the pusher of fig. 6 after insertion into a pusher tube.

Fig. 10 is a schematic view of the pushing device of fig. 5.

Fig. 11 is an exploded view of the pusher of fig. 10.

Fig. 12 is a schematic cross-sectional view taken along line XII-XII in fig. 10.

Fig. 13 is a schematic exploded perspective view of the first and second housings of fig. 11.

Fig. 14 is a schematic plan view of the inside of the first housing in fig. 13.

Fig. 15 is a schematic plan view of the inside of the second housing in fig. 13.

Fig. 16 is a schematic plan view of the outer side of the second housing in fig. 15.

Fig. 17 is a schematic perspective view of the outer gusset of fig. 11.

Fig. 18 is an exploded isometric view of the end cap of fig. 11.

Fig. 19 is a cross-sectional view taken along line XIX-XIX in fig. 18.

Fig. 20 is a schematic exploded perspective view of the first clamping block, the movable block and the second clamping block in fig. 11.

Fig. 21 is a schematic structural view of one side of the first clamping block in fig. 20.

Fig. 22 is a schematic view of another side of the first clamp block of fig. 20.

Fig. 23 is a schematic side view of the second clamp block of fig. 20.

Fig. 24 is an enlarged view of the movable block in fig. 20.

Fig. 25 is an enlarged view of the button in fig. 11.

Fig. 26 is a schematic structural view of the first rotating mechanism in fig. 11.

Fig. 27 is a cross-sectional view taken along line XXVII-XXVII in fig. 26.

Fig. 28 is a schematic perspective view of the rotating post of fig. 26.

Fig. 29 is a schematic perspective view of the second rotating member of fig. 11.

Fig. 30 is a schematic side view of the second rotating member of fig. 29.

FIG. 31 is a cross-sectional view taken along line XXXI-XXXI in FIG. 30.

Fig. 32 is a combination diagram of the pusher of fig. 11.

Fig. 33 is a cross-sectional view taken along line XXXIII-XXXIII in fig. 32.

Detailed Description

The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without any inventive effort, are intended to be within the scope of the invention.

Orientation definition for clarity of description, the end closer to the operator during surgery is referred to as the "proximal end" and the end farther from the operator is referred to as the "distal end", the axial direction refers to the direction parallel to the line connecting the distal center and the proximal center of the medical instrument, and the above definition is for convenience of description only and should not be construed as limiting the invention.

Referring to fig. 1-4, the present invention provides an occluder 10 comprising a proximal occlusion 11, a distal occlusion 15 and a waist 18 disposed between the proximal occlusion 11 and the distal occlusion 15. The proximal end of the proximal end blocking portion 11 is provided with a first tightening member 110, the proximal end blocking portion 11 is provided with a tapered sliding guide structure 111 at the outer periphery of the first tightening member 11, and the inner diameter of the sliding guide structure 111 gradually decreases from the distal end to the proximal end. In this embodiment, the sliding guide structure 111 is an inverted conical surface structure.

The proximal end of the proximal end blocking portion 11 of the plugging device 10 is provided with the conical sliding guide structure 111 at the periphery of the first tightening member 110, when the plugging device 10 is not successfully locked, the plugging device 10 needs to be recovered into the sheath, and the plugging device 10 can easily enter the sheath due to the guiding function of the sliding guide structure 111, so that the plugging device is convenient to use. The outer diameter of the proximal end of the guide and slide structure 111 is slightly smaller than the inner diameter of the distal end of the sheath, which facilitates insertion of the proximal end of the guide and slide structure 111 into the sheath when the occluder 10 is retrieved.

The first blocking piece 11, the second blocking piece 15 and the waist 18 are all made of metal wires in a woven double-layer disc structure with an inner space, and the middle of each metal wire is bent to form the waist 18. The wire may be, but is not limited to, nitinol, cobalt chrome, stainless steel or other biocompatible metallic material, preferably superelastic shape memory alloy nitinol. At least one flow blocking film is disposed inside the proximal blocking portion 11 and/or the distal blocking portion 15, and the flow blocking film may be sewn or adhered to the inside of the proximal blocking portion 11 and the distal blocking portion 15, and the flow blocking film may be, but is not limited to, a polytetrafluoroethylene film, a polyurethane film, a polyimide film, or the like.

In other embodiments, the first blocking member 11, the second blocking member 15, and the waist portion 18 may be cut using metal tubes to form a lattice or frame structure.

As shown in fig. 2, the proximal occlusion 11 comprises a first annular recess 112 connected to the waist 18 and recessed proximally, and a first sidewall 113 connected to the outer edge of the first annular recess 112. The cross section of the first side wall 113 is approximately V-shaped, and the first side wall 113 extends from the outer edge of the first annular groove 112 to the proximal end in a tilting manner for a certain length, then bends to the distal end in a tilting manner, extends and is connected to the distal end of the sliding guide structure 111, so that the first side wall 113 and the sliding guide structure 111 enclose an annular valley 115 recessed to the distal end. The first sidewall 113 and the first annular groove 112 enclose an annular first clamping shoulder 116, and the cross section of the first clamping shoulder 116 is approximately V-shaped.

Specifically, the wire woven in the first annular groove 112 extends in the proximal direction at an angle of 30-45 degrees to the axial direction to form a first sidewall 113, and then is turned back distally to form an annular valley 115. The smoothing structure 18 is formed at the junction of the annular valley 115 and the first tightening member 110. The proximal occlusion 11 provides maximum gripping force when the occluding device 10 begins to grip the ostium, facilitating endothelialization of the occluding device 10.

The first tightening member 110 includes an inner hub 117 disposed proximally of the proximal plug portion 11 and a projection 118 secured to the inner hub 117, with the proximal ends of the wires converging between the inner hub 117 and the projection 118. The wire between the inner hub 117 and the protruding portion 118 may be fixed by welding, clamping, or the like.

In this embodiment, the inner sleeve 117 is a steel sleeve with two open ends, the protruding portion 118 is also a cylinder with two open ends, the inner diameter of the inner sleeve 117 is larger than the outer diameter of the protruding portion 118, the inner sleeve 117 can be arranged inside or outside the proximal plugging portion 11, the inner sleeve 117 is sleeved on the protruding portion 118, and the proximal end of the wire is located between the inner wall of the inner sleeve 117 and the outer wall of the protruding portion 118. Preferably, the inner sleeve 117 is located inside the proximal blocking portion 11, the distal end of the protruding portion 118 extends into the proximal blocking portion 11, the inner sleeve 117 is sleeved on the distal end of the protruding portion 118, and the proximal end of the wire is positioned between the inner wall of the inner sleeve 117 and the outer wall of the distal end of the protruding portion 118 after being folded inwards. The inner sleeve 117 is disposed inside the proximal plug portion 11, and the plugging device 10 can reduce the length of the first tightening member 110 axially protruding from the proximal plug portion 11 after locking, so as to reduce the risk of postoperative complications. The protruding portion 118 is axially provided with a through hole 1182, and an outer wall of the protruding portion 118 is provided with an external thread 1184.

The distal end blocking portion 15 includes a second annular groove 152 connected to the waist 18 and recessed toward the distal end, and a second sidewall 153 connected to an outer edge of the second annular groove 152, the second sidewall 153 extending obliquely distally from the second annular groove 152 and converging at the distal end of the distal end blocking portion 15. The second sidewall 153 encloses a second clamping shoulder 156 with the second annular groove 152, an outer edge of the second clamping shoulder 156 corresponding to an outer edge of the first clamping shoulder 116. When the occluder 10 is occluding a breach, the first and second retaining shoulders 116, 156 are retained on opposite sidewalls around the breach.

The distal end blocking portion 15 further includes a second tightening member 150 disposed at the distal end, and the wire braided in the second annular groove 152 extends distally toward the second tightening member 150 at an angle of 30-45 degrees with respect to the axial direction to form a second sidewall 153, and is then secured to the second tightening member 150 adjacent to the second tightening member 150. The particular configuration of the second annular groove 152, the second sidewall 153 and the second clamping shoulder 156 of the distal occlusion 15 and the first annular groove 112, the first sidewall 113 and the first clamping shoulder 116 of the proximal occlusion 11 provide maximum clamping force when the occluding device 10 begins to clamp the breach and facilitate endothelialization of the occluding device 10.

Referring to fig. 2-3, the second tightening member 150 includes an outer sleeve 157 and a connecting bolt 158 connected to the proximal end of the outer sleeve 157, wherein the distal end of the wire is converged and positioned between the outer sleeve 157 and the distal end of the connecting bolt 158, the connecting bolt 158 extends proximally, an external thread 1582 is provided on the outer wall of the proximal end of the connecting bolt 158, the outer diameter of the proximal end of the connecting bolt 158 is slightly smaller than the inner diameter of the through hole 1182 of the protruding portion 118, and moving the connecting bolt 158 proximally enables the proximal end of the connecting bolt 158 to pass through the through hole 1182 and be screwed to the nut. The wire between the outer sleeve 157 and the connecting peg 158 may be fixed by welding, clamping, or the like. The end of the coupling peg 158 adjacent to the outer hub 157 is provided with a boss 1585 in the radial direction, the outer diameter of the boss 1585 being larger than the inner diameter of the through hole 1182 of the boss 118. The cam 1585 may be circular, square, or other shape, as long as the cam 1585 is retained around the through hole 1182 at the distal end of the protrusion 118. The wire between the outer sleeve 157 and the connecting bolt 158 may be in a fixing manner such as welding or clamping, specifically, the outer sleeve 157 may be a cylinder with two open ends, the distal end of the wire is welded on the inner side of the cylinder, the distal end port of the connecting bolt 158 is provided with a convex surface along the radial direction, the diameter of the convex surface is larger than that of the cylinder, the proximal end of the connecting bolt 158 passes through the cylinder and the convex surface is clamped on the distal end surface of the cylinder, in addition, the outer sleeve 157 may also be in a structure that an inner cavity is arranged in the direction from the proximal end to the distal end, the distal end of the connecting bolt 158 is fixed in the inner cavity, and the wire is welded between the outer sleeve 157 and the connecting bolt 158.

If the flange 1585 is not provided on the connecting bolt 158, during the locking process of the plugging device 10, when the connecting bolt 158 is pulled towards the proximal direction, when the acting force acting on the connecting bolt 158 is larger, the second plugging piece 15 which is fixed with the connecting bolt 158 and is woven by metal wires may be pulled into the break through the through hole 1182 of the protruding part 118, so that the edge of the second plugging piece 15 is tilted to form a horn-like structure, the second plugging piece 15 cannot form a clamping force on tissues around the break after being tilted, and the plugging effect on the break is affected, while the flange 1585 of the connecting bolt 158 of the plugging device 10 of the invention can stop at the distal end of the protruding part 118 when the connecting bolt 158 pulls the distal plugging part 15 close to the break, so as to play a blocking role, ensure that the distal plugging part 15 is positioned in the cavity of the plugging device 10 and cannot be pulled into the break by the connecting bolt 158, prevent the edge of the second plugging piece 15 from tilting, ensure that the first clamping shoulder 116 and the second clamping shoulder 156 form a good plugging effect on the break and a plugging film arranged inside the waist part 11, the distal plugging part 18.

Before the coupling peg 158 is locked with the nut, the coupling peg 158 is positioned inside the occluding device 10 and the proximal end of the coupling peg 158 passes through the waist 18 of the occluding device 10. A screw hole 1583 is axially formed in the middle of the proximal end face of the connecting bolt 158.

The first annular groove 112 and the second annular groove 152 are disposed opposite to the proximal end and the distal end of the waist 18, the first annular groove 112 and the second annular groove 152 enclose an annular space, when the occluder 10 is mounted on the incision, the tissues around the incision are inserted into the annular space, and the first clamping shoulder 116 and the second clamping shoulder 156 can clamp two opposite side walls of the tissues around the incision, and are more beneficial to endothelialization of the occluder.

Preferably, the external threads 1582 of coupler peg 158 are threaded in a direction opposite to the direction of threading of external threads 1184 of boss 118. Specifically, when the external thread 1582 of the coupling pin 158 is a left-handed thread, the external thread 1184 of the protrusion 118 is a right-handed thread, and when the external thread 1582 of the coupling pin 158 is a right-handed thread, the external thread 1184 of the protrusion 118 is a left-handed thread.

In other embodiments, the occluding device 10 may omit the inner hub 117 and the outer hub 157, with the distal end of the wire converging to the distal end of the peg 158 and being positioned by welding and the proximal end of the wire converging to the distal end of the boss 118 and being positioned by welding.

As shown in fig. 5, the present invention also provides an occluder locking system comprising an occluder 10, a sheath bending device 20, a dilator 30, a loader 40 disposed at the proximal end of the sheath bending device 20, and a pusher device 60 disposed at the proximal end of the loader 40. The sheath bending apparatus 20 comprises a housing 21, a sheath 23 disposed proximally within the housing 21, and an adjustment mechanism 25 for bending the flexible distal end of the sheath 23. The loader 40 includes a loading tube 42 and a sealing seat 44 disposed at a proximal end of the loading tube 42, and a distal end of the loading tube 42 is insertable into the sheath 23. The pushing device 60 may push the plugging device 10, where the pushing device 60 includes a housing 61 having a receiving space, a first pushing component 64 partially disposed in the housing 61, a second pushing component 67 partially sleeved on the housing 61, and a pushing assembly 68, and a proximal end of the pushing assembly 68 is disposed in the housing 61.

The dilator 30 is an elongated cylindrical structure with the distal end of the dilator 30 tapering in diameter to form a cone-like structure. Specifically, the dilator 30 includes a dilating rod 32 and a connecting portion 35 disposed at a proximal end of the dilating rod 32, wherein a distal end of the dilating rod 32 is gradually reduced in diameter to form a conical-like structure, and the conical-like structure facilitates insertion of the dilating rod 32 into the sheath 23. During surgery, the dilator 30 is first assembled into the sheath bending device 20 to form a dilating assembly.

As shown in fig. 6-9, the push assembly 68 includes a pusher 682, a push tube 684 movably sleeved over the pusher 682, and a nut 689 positioned within the distal end of the push tube 684. The distal end of the pusher 682 is removably attached to the peg 158 of the occluding device 10, and the inner wall of the distal end of the push tube 684 is provided with internal threads 6842 corresponding to the external threads 1184 of the tab 118. The first pushing component 64 comprises a sliding mechanism 65, the sliding mechanism 65 can drive the pushing piece 682 to axially and reciprocally slide in the pushing tube 684 so as to drive the connecting bolt 158 to abut against or be far away from a screw hole of the nut 689, and the second pushing component 67 comprises a rotating mechanism, and the rotating mechanism can drive the pushing tube 684 to rotate and drive the nut 689 to rotate so as to enable the connecting bolt 158 to be in threaded connection with the nut 689. During the screwing of the coupling pin 158 to the nut 689, since the external thread 1582 of the coupling pin 158 is screwed in the opposite direction to the external thread 1184 of the protrusion 118, the coupling pin 158 and the nut 689 are fastened in the opposite direction to the external thread 1184 of the protrusion 118 and the internal thread 6842 of the push tube 684, and the external thread 1184 of the protrusion 118 and the internal thread 6842 of the push tube 684 can be separated. Namely, when the connecting bolt 158 is in threaded connection with the nut, the protruding part 118 and the push pipe 684 can be separated, and when the connecting bolt 158 is separated from the nut, the protruding part 118 and the push pipe 684 can be in threaded connection, so that the plugging device 10 is high in locking reliability, good in plugging effect, convenient to use and simple to operate.

Specifically, the pushing assembly 68 is a wire rope assembly, the pushing member 682 is a wire rope with good elasticity, the pushing tube 684 is a wire rope tube with good elasticity, and the wire rope is movably inserted into the wire rope tube. The push tube 684 includes a body segment 6841 and an extension segment 6843 disposed at a distal end of the body segment 6841, a nut 689 positionable within the extension segment 6843, and internal threads 6842 disposed on an inner wall of the distal end of the extension segment 6843, the internal threads 6842 being mateable with external threads 1184 of the boss 118. When the occluding device 10 is coupled to the push assembly 68, the threaded tightening direction of the extension segment 6843 and the protrusion 154 is opposite to the tightening direction of the coupling peg 158 and the nut 689, and the threads and pitch of the extension segment 6843 and the protrusion 154 are equal to or greater than the threads and pitch of the nut 689 such that the proximal end of the coupling peg 158 extends beyond the proximal end face of the nut 689.

The outer wall of the distal end of the pusher member 682 is provided with external threads 6822 that mate with the threaded bore 1583 of the coupler peg 158, and the distal end of the pusher member 682 is movable through the nut 689 and extension 6843. Specifically, a columnar connecting rod 6821 is axially protruding from the middle of the distal surface of the pusher 682, the outer diameter of the connecting rod 6821 is smaller than the outer diameter of the pusher 682, and the external thread 6822 is located on the outer wall of the distal end of the connecting rod 6821.

The outer diameter of the body segment 6841 is smaller than the outer diameter of the extension segment 6843, the inner diameter of the body segment 6841 is smaller than the inner diameter of the extension segment 6843, a step surface 6845 is formed inside the push tube 684 between the proximal end of the extension segment 6843 and the distal end surface of the body segment 6841, and the nut 689 can abut the step surface 6845. The inner wall of the proximal end of the extension 6843 is provided with a snap groove 6846, the nut 689 can be snapped into the snap groove 6846, the snap groove 6846 can prevent the nut 689 from rotating within the push tube 684, and the nut 689 can slide axially within the extension 6843. Specifically, the engaging groove 6846 is formed by radially and regularly recessing an inner wall at a proximal end of the extending section 6843, the engaging groove 6846 may engage the nut 689, and the nut 689 may be, for example, a hexagonal nut, and the engaging groove 6846 is a hexagonal groove corresponding to the hexagonal nut, that is, the radial cross section of the engaging groove 6846 is hexagonal. Therefore, when the nut 689 is engaged in the engagement groove 6846, the nut 689 cannot rotate relative to the push tube 684, but the nut 689 slides axially within the extension 684, and the nut 689 abuts the stepped surface 6845.

Referring to fig. 10 to 12, the first pushing assembly 64 includes a sliding mechanism 65 and a first rotating mechanism 66, the sliding mechanism 65 can drive the pushing member 682 to slide and position axially in the pushing tube 684, the first rotating mechanism 66 can drive the pushing member 682 to rotate in the pushing tube 684, the second pushing assembly 67 includes a second rotating mechanism 670, and the second rotating mechanism 670 can drive the pushing tube 684 to rotate outside the pushing member 682.

The sliding mechanism 65 of the pushing device 60 can drive the pushing member 682 to axially slide in the pushing tube 684, can drive the proximal end of the connecting bolt 158 to pass through the through hole 153 of the protruding portion 118 to abut against or be away from the nut 689 positioned in the pushing tube 684, the first rotating mechanism 66 can drive the pushing member 682 to rotate in the pushing tube 684, and can realize the threaded connection or disconnection of the external thread 6822 of the pushing member 682 and the screw hole 1583 of the connecting bolt 158, and the second rotating mechanism 670 can drive the pushing tube 684 to rotate outside the pushing member 682, and can drive the nut 689 to rotate, so that the nut 689 is in threaded connection with the connecting bolt 158 and the external thread 1184 of the protruding portion 118 is separated from the internal thread 6842 of the pushing tube 684, or the nut 689 is separated from the connecting bolt 158 and the external thread 1184 of the protruding portion 118 is in threaded connection with the internal thread 6842 of the pushing tube 684. The pushing device 60 is simple to operate and convenient to use, and improves the reliability and efficiency of the pushing device 60, thereby reducing the time of surgery.

The housing 61 includes a first housing 611, a second housing 613, an outer pinch plate 615 and an end cover 616, where the first housing 611 is covered on the second housing 613 to form a tube-like structure with two open ends, the sliding mechanism 65 is axially disposed in the tube-like structure, the first rotating mechanism 66 is disposed at a proximal end of the tube-like structure, the second rotating mechanism 670 is disposed at a distal end of the tube-like structure, and the end cover 616 is disposed at a distal end of the second rotating mechanism 670.

As shown in fig. 13 and 15, at least one first supporting piece 6112 and at least one second supporting piece 6113 are disposed at the distal end of the inner wall of the first housing 611 along the axial direction, and at least one third supporting piece 6115 is disposed at the proximal end of the inner wall of the first housing 611. The first supporting piece 6112, the second supporting piece 6113 and the third supporting piece 6115 are all semicircular annular pieces, and the first supporting piece 6112 and the second supporting piece 6113 are arranged at intervals. The axial lines of the first support piece 6112, the second support piece 6113 and the third support piece 6115 extend along the axial direction, and the axial lines of the first support piece 6112, the second support piece 6113 and the third support piece 6115 are overlapped.

In this embodiment, the number of the first supporting pieces 6112 is two, the two first supporting pieces 6112 are axially spaced and parallel, the number of the second supporting pieces 6113 is one, the number of the third supporting pieces 6115 is two, and the two third supporting pieces 6115 are axially spaced and parallel.

In other embodiments, the number of the first support pieces 6112, the second support pieces 6113, and the third support pieces 6115 may be other values.

The outer wall of the first housing 611 is provided with a rectangular planar surface 6110, the length direction of the planar surface 6110 extending in the axial direction, i.e., the planar surface 6110 extends from the distal end to the proximal end. The plane 6110 is provided with a strip-shaped opening 6116 along the axial direction, the strip-shaped opening 6116 is positioned between the second supporting sheet 6113 and the third supporting sheet 6115, and the strip-shaped opening 6116 extends from the distal end to the proximal end of the first housing 611. The inner wall of the first housing 611 is provided with a rack 6117 on at least one side of the strip-shaped opening 6116, the rack 6117 extending from the distal end to the proximal end of the strip-shaped opening 6116. A plurality of clamping pieces 6118 are respectively protruded on two opposite side walls of the first shell 611.

In this embodiment, the inner wall of the first housing 611 is provided with two opposite sides of the strip-shaped opening 6116 along the axial direction, and each strip-shaped groove is provided with a rack 6117.

As shown in fig. 13, 15 and 16, the structure of the second housing 613 is similar to that of the first housing 611, at least one fourth supporting piece 6132 and at least one fifth supporting piece 6133 are axially disposed at the distal end of the inner wall of the second housing 613, and at least one sixth supporting piece 6135 is disposed at the proximal end of the inner wall of the second housing 613. The fourth supporting plate 6132, the fifth supporting plate 6133 and the sixth supporting plate 6135 are all semicircular annular plates, and the fourth supporting plate 6132 and the fifth supporting plate 6133 are arranged at intervals. The axial lines of the fourth support piece 6132, the fifth support piece 6133 and the sixth support piece 6135 extend along the axial direction, and the axial lines of the fourth support piece 6132, the fifth support piece 6133 and the sixth support piece 6135 overlap. When the first housing 611 is covered on the second housing 613, the first supporting piece 6112, the second supporting piece 6113 and the third supporting piece 6115 of the first housing 611 are respectively in one-to-one correspondence with the fourth supporting piece 6132, the fifth supporting piece 6133 and the sixth supporting piece 6135 of the second housing 613, the first supporting piece 6112 and the corresponding fourth supporting piece 6132 enclose a circular supporting piece, the second supporting piece 6113 and the fifth supporting piece 6133 enclose a circular supporting piece, and the third supporting piece 6115 and the corresponding sixth supporting piece 6135 enclose a circular supporting piece.

In this embodiment, the number of the fourth supporting pieces 6132 is two, the two fourth supporting pieces 6132 are spaced in parallel, the number of the fifth supporting pieces 6133 is one, the number of the sixth supporting pieces 6135 is two, and the two sixth supporting pieces 6135 are spaced in parallel.

In other embodiments, the number of fourth, fifth and sixth support pieces 6132, 6133, 6135 may be other values.

The inner wall of the second housing 613 is axially protruding with at least one rail 6136, the rail 6136 is located between the fifth supporting piece 6133 and the sixth supporting piece 6135, and the rail 6136 extends from the distal end to the proximal end. In this embodiment, two guide rails 6136 are protruded in parallel at a middle portion of the inner wall of the second housing 613, and a plurality of positioning blocks 6137 are disposed between the two guide rails 6136 along an axial direction at intervals, and each positioning block 6137 is provided with a clamping hole. The middle part of the outer wall of the second housing 613 is provided with a mounting port 6138, and the periphery of the mounting port 6138 of the second housing 613 is provided with a plurality of clamping holes 6139. A plurality of elastic clamping hooks 6131 are respectively protruded on two opposite side walls of the second housing 613, and the clamping hooks 6131 are in one-to-one correspondence with the clamping pieces 6118 of the first housing 611.

As shown in fig. 17, the outer buckle 615 is a convex arc-shaped piece, the outer buckle 615 corresponds to the mounting opening 6138 of the second housing 613, a plurality of positioning posts 6151 and a plurality of hooks 6153 are arranged on the side surface of the outer buckle 615 facing the outer buckle 615 in a protruding manner, the positioning posts 6151 correspond to the clamping holes of the positioning block 6137 of the second housing 613 one by one, and the hooks 6153 correspond to the clamping holes 6139 of the second housing 613 one by one. The outer wall of the outer pinch plate 615 is provided with anti-slip stripes or protrusions, etc. to increase friction, facilitate the gripping of the conveying device 60 by fingers, and facilitate the operation of the conveying device 60.

As shown in fig. 18 and 19, the end cover 616 is in a cone structure, the end cover 616 comprises a cap body 6160 and a sleeve head 6165 connected to the distal end of the cap body 6160, the end cover 616 is axially provided with a through hole 6161, and the through hole 6161 penetrates through the middle parts of the cap body 6160 and the sleeve head 6165. A conical cavity is formed in the cap body 6160, an annular groove 6162 is formed in the inner wall of the proximal end of the cap body 6160, and the axial lead of the annular groove 6162 is coincident with the axial lead of the through hole 6161. The back end of the cap body 6160 is provided with two opposite clamping blocks 6164 in the conical cavity.

The sleeve head 6165 is clamped at the far end of the cap body 6160, specifically, the far end of the cap body 6160 is provided with a clamping ring 6163 in a protruding mode on the inner peripheral surface of the through hole 6161, the proximal end surface of the sleeve head 6165 is provided with an extending column in a protruding mode on the periphery of the through hole 6161, the proximal end of the extending column is provided with a pair of protruding pieces 6167 in a protruding mode in a radial mode, after the sleeve head 6165 is inserted into the through hole 6161 of the cap body 6160 in a clamping mode through extending, the protruding pieces 6167 are clamped on the clamping ring 6163 of the cap body 6160, and therefore the sleeve head 6165 is fixed to the cap body 6160. The sleeve head 6165 is made of soft materials such as rubber, silica gel and the like, and the proximal end of the pushing assembly 601 passes through the sleeve head 6165 and the through hole 6161 of the cap body 6160 and is then connected into the shell body 61. Because the hub 6165 is made of a soft material, the hub 6165 can reduce the amount of friction and wear caused by wobble of the push assembly 601 and the distal port of the end cap 616.

Referring to fig. 2 to 31, the sliding mechanism 65 is disposed in the housing 61 in an axial sliding manner, and the sliding mechanism 65 includes at least one guide rail 651 extending in the axial direction and disposed in the housing 61, a movable block 653 slidably disposed through the at least one guide rail 651, and a sliding member 650 capable of driving the movable block 653 to slide along the guide rail 651. The proximal end of the pusher 682 is fixed to the movable block 653, and the slider 650 includes a first clamp 654 and a second clamp 655, and a button 656 partially exposed from the housing 61 and connected to the slider 650, the first clamp 654 being movable toward and away from the second clamp 655. The movable block 653 is disposed between the first clamping block 654 and the second clamping block 655, the first clamping block 654 and the second clamping block 655 are close to each other to clamp the movable block 653 between the first clamping block 654 and the second clamping block 655, the first clamping block 654 and the second clamping block 655 are far away from each other to release the clamping of the movable block 653, and the movable block 653 can rotate.

In this embodiment, two guide rails 651 are axially disposed in parallel with each other in the housing 61.

The first clamping block 654 is approximately in a semicircular tube structure, a rectangular top surface 6541 is arranged in the middle of the outer wall of the first clamping block 654, and the length direction of the top surface 6541 extends along the axial direction of the first clamping block 654. Part of the structure of the first clamping block 654 can pass through the strip-shaped opening 6116 and can slide along the strip-shaped opening 6116, specifically, a sliding strip 6542 is convexly arranged in the middle of the top surface 6541, the length direction of the sliding strip 6542 extends along the length direction of the top surface 6541, and the sliding strip 6542 can be slidably inserted into the strip-shaped opening 6116 of the first shell 611. The top surface 6541 is provided with a latch 6544 on at least one side of the sliding strip 6542, and the latch 6544 can be clamped with the rack 6117 corresponding to the first housing 611. Preferably, the top surface 6541 is provided with two latches 6544 on two opposite sides of the sliding strip 6542, and the two latches 6544 can be respectively clamped to the two racks 6117 of the first housing 611. The top surface 6541 is provided with connecting posts 6545 at two opposite ends of the sliding strip 6542. Two guide posts 6546 and a guide slide plate 6547 are respectively arranged on two side surfaces of the first clamping block 654, which are opposite to the top surface 6541, and the guide slide plate 6547 on each side is positioned between the two guide posts 6546 on the same side. A first clamping groove 6548 is formed in the middle of the inner wall of the first clamping block 654, and the first clamping groove 6548 can accommodate the outer wall of the movable block 653.

The second clamping block 655 is in a semicircular tube structure, two guide grooves 6552 spaced from each other are axially formed in the middle of the outer wall of the first clamping block 654, the two guide grooves 6552 correspond to the guide rail 6136 of the second housing 613, and the second clamping block 655 can slide along the guide rail 6136. Two opposite side surfaces of the second clamping block 655 are respectively provided with two guide sliding holes 6554 and a guide hole 6556, and the guide hole 6556 on each side is positioned between the two guide sliding holes 6554 on the same side. A second clamping groove 6558 is formed in the middle of the inner wall of the second clamping block 655, and the second clamping groove 6558 can accommodate the outer wall of the movable block 653.

The movable block 653 is a cylinder, and the proximal end of the pushing member 682 is fixed to the middle part of the movable block 653, specifically, the middle part of the distal end surface of the movable block 653 is provided with a fixing hole 6532 along the axial direction thereof, and the proximal end of the pushing member 682 is fixed in the fixing hole 6552. The end face of the movable block 653 is provided with two through holes 6534 on two opposite sides of the fixed hole 6552, and each through hole 6534 extends axially and penetrates the proximal end face and the distal end face of the movable block 653. The outer wall of the movable block 653 is provided with a plurality of welding holes 6535 communicating with the fixing holes 6552, and the pushing member 682 is fixed to the movable block 653 by adding solder into the welding holes 6535.

An elastic member 658 is disposed between the first clamp block 654 and the second clamp block 655, the elastic member 658 being capable of urging the first clamp block 654 away from the second clamp block 655. Preferably, the spring 658 is a spring that is sleeved outside of the guide strut 6546.

The middle part of the outer wall of the button 656 is provided with a concave 6561, the surface of the concave 6561 is provided with a plurality of anti-slip strips 6563, and fingers can be inserted into the concave 6561, so that the button 656 can be conveniently operated. The opposite ends of the side of the button 656 facing away from the recess 6561 are respectively provided with a connecting block 6564 in a protruding manner, and the side of each connecting block 6564 facing away from the recess 6561 is provided with a connecting hole 6566. The two connection holes 6566 correspond to the two connection posts 6545 of the first clamp block 654.

In other embodiments, the button 656 may also be directly provided on the slider 650, and further, the first clamping block 654 is provided with a button passing through the strip-shaped opening 6116.

The first rotating mechanism 66 includes a first rotating member 662 fixed to the guide rail 651 and a rotating post 664 rotatably provided in the housing 61 along the axis of the pusher 682. Specifically, the first rotating mechanism 66 is fixedly connected to the proximal end of the guide sliding rail 651, the rotating post 664 is fixedly connected to the distal end of the guide sliding rail 651, and the axial line of the guide sliding rail 651 is parallel to the axial line of the pushing member 682 at intervals. The first rotating member 662 is rotatably disposed at the proximal end of the housing 61 along the axial line of the pushing member 682, and the rotation of the first rotating member 662 drives the movable block 653 and the rotating post 664 to rotate through the guide rail 651, thereby rotating the pushing member 682.

Specifically, the first rotating member 662 includes a handle portion 6621 and a rotating rod 6623 protruding from a middle portion of a distal end surface of the handle portion 6621, the rotating rod 6623 is a cylinder, two annular guide grooves 6625 are formed in a circumferential direction of an outer wall of the rotating rod 6623, the two guide grooves 6625 correspond to an annular support piece surrounded by a third support piece 6115 of the first housing 611 and a sixth support piece 6135 of the second housing 613, an axial lead of the two guide grooves 6625 coincides with an axial lead of the first rotating member 662, and the first rotating member 662 can rotate along the guide grooves 6625. The end surface of the rotating rod 6623 facing away from the handle portion 6621 is provided with two spaced fixing holes 6626, the axial lead of the two fixing holes 6626 is not overlapped with the axial lead of the rotating rod 6623, and the proximal ends of the two guide slide rails 651 are respectively fixed in the two fixing holes 6626. The outer wall of the handle portion 6621 is provided with a plurality of anti-slip grooves 6627 to facilitate rotation of the first rotation member 662.

The rotating post 664 is a cylinder, the outer wall of the rotating post 664 is provided with a guide groove 6642 along the circumferential direction, the guide groove 6642 corresponds to an annular support piece surrounded by the second support piece 6113 of the first shell 611 and the fifth support piece 6133 of the second shell 613, and the rotating post 664 can rotate along the guide groove 6642. The middle of the rotating post 664 is axially provided with a through hole 6643 passing through the proximal and distal end surfaces thereof, and the pusher 682 is movably passed through the through hole 6643. The axis of the through hole 6643 coincides with the axis of the guide groove 6642. The proximal end surface of the rotating post 664 is provided with two fixing holes 6646 on two opposite sides of the through hole 6643, and the distal ends of the two guide slide rails 651 are respectively fixed in the two fixing holes 6646.

The second rotating member 670 is rotatably disposed at the distal end of the housing 61 along the axial line of the pushing member 682, the second rotating member 670 is a cylinder, the middle of the second rotating member 670 is axially provided with a through hole 6701, the proximal end of the pushing tube 684 can be fixed in the through hole 6701, and the pushing member 682 can movably pass through the through hole 6701. The axis of the through hole 6701 coincides with the axis of the push pipe 684, and the axis of the second rotary member 670 coincides with the axis of the through hole 6701.

Specifically, the second rotating member 670 includes a cylindrical operation portion 6702, a rotating portion 6704 protruding from a middle portion of a proximal end surface of the operation portion 6702, and an annular tab 6705 protruding from a distal end surface of the operation portion 6702. The outer wall of the operation portion 6702 is provided with anti-slip strips which facilitate the rotation of the second rotation member 670 by the finger. The rotating portion 6704 is a cylinder, two annular guide grooves 6706 are formed in the outer wall of the rotating portion 6704 along the circumferential direction of the rotating portion 6704, the two guide grooves 6706 correspond to annular support pieces surrounded by the first support piece 6112 of the first housing 611 and the fourth support piece 6132 of the second housing 613, the axial lines of the two guide grooves 6706 are coincident with the axial line of the through hole 6701, and the second rotating member 670 can rotate along the guide grooves 6706. The axial line of the annular lug 6705 coincides with the axial line of the through hole 6701, and the annular lug 6705 is provided with two opposite clamping hooks 6707 along the radial direction thereof, and the two clamping hooks 6707 correspond to the two clamping blocks 6164 of the cap body 6160. The inner wall of the proximal end of the through hole 6701 is provided with an inner thread 6708, and the outer wall of the proximal end of the push tube 684 is provided with an outer thread corresponding to the inner thread 6708.

Referring to fig. 10-33, when assembling the pushing device 60, the proximal ends of the pushing members 682 are movably inserted through the through holes 6643 of the rotating posts 664 and then fixed in the fixing holes 6532 of the movable blocks 653, the two guide rails 651 are slidably inserted through the two through holes 6534 of the movable blocks 653, the distal ends of the two guide rails 651 are respectively fixed in the two fixing holes 6646 of the rotating posts 664, the proximal ends of the two guide rails 651 are respectively fixed in the two fixing holes 6626 of the first rotating member 662, the movable blocks 653 are slidably inserted through the guide rails 651 and positioned between the first rotating member 662 and the rotating posts 664, the elastic members 658 are respectively sleeved on the guide posts 6546, the movable blocks 653 are placed between the first clamping blocks 654 and the second clamping blocks 655, the first clamping blocks 654 are covered on the second clamping blocks 655, the movable members 653 are movably clamped in the first clamping grooves 6548 of the first clamping blocks 6548 and the second clamping grooves 6558 of the second clamping blocks 655, the movable blocks 655 are axially abutted against the inner surfaces of the second clamping blocks 6556, the guide blocks 6556 are axially abutted against the corresponding to the second clamping blocks 6556, and are prevented from being axially moved into the corresponding to the second clamping holes 6556, and the guide blocks 6547 are axially positioned against the corresponding to the second clamping blocks 6556, and the guide blocks 6547 are prevented from being axially moved relative to the corresponding to the guide blocks. The two guide slide rails 651 are disposed between the first housing 611 and the second housing 613, so that the connecting post 6545 of the first clamping block 654 faces the bar-shaped opening 6116 of the first housing 611, the second supporting plate 6113 of the first housing 611 is inserted into the guide groove 6642 of the rotating post 664, and the two third supporting plates 6115 are respectively inserted into the two guide grooves 6625 of the first rotating member 662. At this time, the sliding bar 6542 and the connecting post 6545 are inserted into the bar-shaped opening 6116, the sliding bar 6542 can slide along the axial direction of the bar-shaped opening 6116, and the two latches 6544 of the first clamping block 654 correspond to the two racks 6117 respectively. The two connection blocks 6564 of the button 656 are sleeved on the two connection columns 6545, the first housing 611 is exposed out of the recess 6561 of the button 656, and the button 656 can slide along the strip-shaped opening 6116.

The sleeve head 6165 is sleeved at the far end of the cap body 6160, specifically, a pair of protruding pieces 6167 of the sleeve head 6165 are clamped at a clamping ring 6163 of the cap body 6160, the end cover 616 is clamped at the far end of the second rotating member 670, specifically, an annular protruding piece 6705 is inserted into an annular groove 6162 of the cap body 6160, and two clamping hooks 6707 are respectively clamped at two clamping blocks 6164, so that the end cover 616 is fixed on the second rotating member 670, and the axial lead of a through hole 6161 of the end cover 616 is overlapped with the axial lead of a through hole 6701 of the second rotating member 670. In other embodiments, the hook 6707 of the second rotating member 670 and the clamping block 6164 of the cap body 6160 may be omitted, and the annular tab 6705 of the second rotating member 670 is rotatably inserted into the annular groove 6162 of the cap body 6160, so that the end cap 616 is rotatably connected to the distal end of the second rotating member 670. The proximal end of the push tube 684 is fixed in the through hole 6701 of the second rotating member 670 after passing through the through hole 6161 of the end cap 616, and specifically, the external thread of the push tube 684 is screwed with the internal thread 6708 of the second rotating member 670. In other embodiments, the proximal end of the push tube 684 may be secured within the through bore 6161 by welding, cementing, or clamping.

The distal end of the pushing member 682 is inserted through the through hole 6701 and the pushing tube 684 from the proximal end of the second rotating member 670, so that the second rotating member 670 slides to the distal end of the first housing 611, the two first supporting pieces 6112 of the first housing 611 are respectively inserted into the two guiding grooves 6706 of the second rotating member 670, the second housing 613 is connected to the first housing 611, and the clamping hooks 6131 of the second housing 613 are respectively clamped to the clamping pieces 6118 of the first housing 611. At this time, the two fourth supporting pieces 6132 of the second housing 613 are respectively inserted into the two guiding grooves 6706 of the second rotating member 670, the fifth supporting piece 6133 is received in the guiding groove 6642 of the rotating post 664, the two sixth supporting pieces 6135 are respectively inserted into the two guiding grooves 6625 of the first rotating member 662, the two guiding rails 6136 are respectively received in the two guiding grooves 6552 of the second clamping block 655, the elastic member 658 pushes the clamping teeth 6544 of the first clamping block 654 to be clamped to the rack 6117, and the operating portion 6702 of the second rotating member 670 is exposed out of the housing 61. The outer pinch plate 615 is then clamped in the mounting port 6138 of the second housing 613, specifically, the positioning column 6151 of the outer pinch plate 615 is clamped in the clamping hole of the corresponding positioning block 6137, and the clamping hook 6153 is clamped in the corresponding clamping hole 6139, so that the mounting is completed.

When the pushing device is used, the push button 656 is pressed to move the first clamping block 654 towards the second clamping block 655, the elastic piece 658 is elastically deformed until the movable block 653 is clamped and positioned by the first clamping block 654 and the second clamping block 655, the latch 6544 of the first clamping block 654 is separated from the rack 6117, the push button 656 is slid proximally or distally along the strip-shaped opening 6116 of the first housing 611, the movable block 653 slides proximally or distally along the first clamping block 654 and the second clamping block 655 to drive the pushing piece 682 to slide proximally or distally in the pushing tube 684 so as to realize axial sliding of the pushing piece 682, when the pushing piece 682 slides to a proper position, the pressing of the push button 656 is released, the elastic piece 658 is elastically reset to push the first clamping block 654 away from the second clamping block 655, the latch 6544 of the first clamping block 654 is clamped to the rack 6117, and the sliding piece 650 is positioned so as to prevent the movable block 653 from sliding in the axial direction, so that the pushing piece 682 is positioned in the axial direction. When the pushing member 682 needs to be rotated, the pressing of the button 656 is released, so that the first clamping block 654 is far away from the second clamping member 655, and the first rotating member 662 is rotated to drive the guide rail 651, the movable block 653 and the rotating post 664 to rotate, i.e., the movable member 653 can rotate along the axial line of the pushing member 682 in the space enclosed by the first clamping groove 6548 of the first clamping block 654 and the second clamping groove 6558 of the second clamping block 655, thereby driving the pushing member 682 to rotate relative to the pushing tube 684. When it is necessary to rotate the push tube 684, the operation portion 6702 of the second rotating member 670 rotates the second rotating member 670 along the axial line of the push member 682, and the push tube 684 rotates with the second rotating member 670 because the proximal end of the push tube 684 is fixed in the through hole 6701 of the second rotating member 670.

The sliding mechanism 65 of the pushing device 60 can drive the pushing member 682 to slide axially, so as to conveniently change the position of the occluder fixed to the distal end of the pushing member 682 in the blood vessel, and can control the release speed of the occluder, when the pushing member 682 is moved to a proper position, the button 656 is released, and the first clamping block 654 moves toward the first housing 611 under the restoring force of the elastic member 658, so that the latch 6544 is engaged with the rack 6117, thereby realizing the positioning of the pushing member 682 and the occluder, and therefore, the sliding mechanism 65 can conveniently and reliably move and position the occluder.

In the plugging device locking system, in the interventional operation, after the puncture position is determined and the puncture is finished, the distal end of the expansion rod 32 of the expander 30 passes through the insertion sheath 23 from the proximal end of the sheath tube bending-adjustable device 20 and is exposed out of the distal end of the sheath tube 23, and the distal end of the expander 30 is gradually reduced in diameter to form a conical-like structure, under the development effect of an imaging instrument, an operator can conveniently guide the sheath tube to the vicinity of a lesion position by means of the distal end structure of the expander 30, and after the sheath tube 23 reaches the vicinity of the lesion position, the expander 30 is withdrawn again, so that the sheath tube 23 is reserved in the body to establish a channel from outside the body to inside the body; the distal end of the pushing assembly 68 of the pusher 60 is passed through the sealing seat 44 and the loading tube 42 of the loader 40, the distal end of the pusher 682 and the distal end of the push tube 684 are simultaneously detachably secured to the occluder 10, the relative positions of the pusher 682 and the push tube 684 are changed to axially stretch the occluder 10, the pushing assembly 68 is moved proximally to insert the slide guide structure 111 of the occluder 10 into the loading tube 42 to facilitate easy retraction of the occluder 10 into the inner lumen of the loading tube 42 of the loader 40, the distal end of the loading tube 42 is inserted into the sheath 23 to provide a delivery system for loading the occluder 10, the housing 61 of the pusher 60 is held in the distal end of the sheath 23 to push the occluder 10, the sheath 23 distal end of the sheath 23 is moved into the proximal end of the sheath 20 by rotating the sheath 23 and the sheath 656 to slowly push the push assembly 68 in the direction of the breach of the delivery device 60 to release the occluder 10 from the sheath 23 and to the proximal end of the push button 656 to release the occluder 60 in the proper axial direction, the proximal end blocking part 11 and the distal end blocking part 15 of the blocking device 10 are positioned at the two ends of the break, and the blocking locking of the blocking device 10 to the break and the separation of the pushing piece 682 and the pushing tube 684 from the blocking device 10 are completed under the action of the sliding mechanism 65, the first rotating mechanism 66 and the second rotating mechanism 670 of the conveying device 60. At this time, the first clamping shoulder 116 of the proximal end blocking portion 11 and the second clamping shoulder 156 of the distal end blocking portion 15 clamp the tissue around the break well, and the endothelialization of the blocking device is facilitated.

The foregoing is a description of embodiments of the present invention, and it should be noted that, for those skilled in the art, modifications and variations can be made without departing from the principles of the embodiments of the present invention, and such modifications and variations are also considered to be within the scope of the present invention.

Claims

1. An occluder comprising a proximal occlusion part, characterized in that,

The proximal end of the proximal end plugging part is provided with a first tightening member, the first tightening member comprises an inner sleeve arranged at the proximal end of the proximal end plugging part and a protruding part fixed with the inner sleeve, the protruding part is axially provided with a through hole, the outer wall of the protruding part is provided with external threads, the external threads of the protruding part are used for corresponding to the internal threads of the inner wall of the distal end of the pushing pipe, the distal end of the pushing pipe is internally provided with a nut, the periphery of the proximal end plugging part on the first tightening member is provided with a conical sliding guide structure, and the inner diameter of the sliding guide structure is gradually reduced from the distal end to the proximal end;

The plugging device further comprises a distal plugging part, the distal plugging part is a structure with an inner space formed by weaving metal wires, the distal plugging part further comprises an outer connecting sleeve and a connecting bolt connected with the outer connecting sleeve, an outer thread is arranged on the outer wall of the proximal end of the connecting bolt, the connecting bolt can penetrate through the through hole and is screwed with the nut, the direction of the outer thread of the connecting bolt is opposite to that of the outer thread of the protruding part, so that when the connecting bolt is screwed with the nut, the protruding part is separated from the pushing pipe, and when the connecting bolt is separated from the nut, the protruding part is screwed with the pushing pipe.

2. The occluder of claim 1, wherein the device comprises a plurality of inflatable cells,

The stopper also comprises a waist part arranged between the proximal end blocking part and the distal end blocking part, wherein the proximal end blocking part comprises a first annular groove which is connected with the waist part and is sunken towards the proximal end, and a first side wall which is connected with the outer edge of the first annular groove, the first side wall is bent to the distal end after obliquely extending towards the proximal end for a certain length from the first annular groove and then obliquely extending towards the distal end to be connected to the distal end of the sliding guide structure, the first side wall and the sliding guide structure enclose an annular valley which is sunken towards the distal end, and the first side wall and the first annular groove enclose a first clamping shoulder.

3. The occluder of claim 2, wherein the device comprises,

The proximal plugging part is a structure with an inner space formed by weaving metal wires, the metal wires woven by the first annular groove extend to the proximal direction to form the first side wall at an included angle of 30-45 degrees with the axial direction, and then the metal wires are folded back to the distal end to form the annular valley.

4. The occluder of claim 2, wherein the device comprises,

The distal end shutoff portion includes with the waist links to each other and towards the second annular groove of distal end concave and connect in the second lateral wall of the outward flange of second annular groove, the second lateral wall is followed the second annular groove is to distal end slope extend and assemble in the distal end of distal end shutoff portion, the second lateral wall with the second annular groove encloses into the second centre gripping shoulder, the second centre gripping shoulder with first centre gripping shoulder sets up relatively.

5. The device according to claim 4, it is characterized in that the method comprises the steps of,

The distal end plugging part further comprises a second tightening member arranged at the distal end, the metal wire woven by the second annular groove extends to the distal end to be close to the second tightening member in the direction of the second tightening member at an included angle of 30-45 degrees with the axis direction to form the second side wall, and the metal wire is close to the second tightening member again and is fixed to the second tightening member.

6. The device according to claim 4, it is characterized in that the method comprises the steps of,

The first annular groove and the second annular groove are oppositely arranged at the proximal end and the distal end of the waist.

7. The device according to claim 3, it is characterized in that the method comprises the steps of,

The proximal ends of the wires are positioned in a converging relationship between the inner hub and the projections.

8. The occluder of claim 7, wherein the at least one of a polymer and a polymer comprises,

The distal ends of the wires are positioned in a converging relationship between the outer sleeve and the connecting pin, which extends proximally.

9. The occluder of claim 8, wherein the at least one of a balloon and a balloon is formed,

The connecting bolt is close to one end of the external sleeve and is provided with a convex disc in the radial direction, and the outer diameter of the convex disc is larger than the inner diameter of the through hole.

10. A locking system for a plugging device is characterized in that,

The device comprises a sheath tube bending-adjustable device, a loader, a pushing device and the plugging device according to any one of claims 1 to 9, wherein the sheath tube bending-adjustable device comprises a sheath tube, the loader comprises a loading tube, the distal end of the loading tube is inserted into the sheath tube, the pushing device comprises a pushing combination, and the pushing combination can recycle the plugging device into the sheath tube.