CN111772784B

CN111772784B - Ablation Device

Info

Publication number: CN111772784B
Application number: CN202010860013.1A
Authority: CN
Inventors: 李梦梦; 龙德勇; 桑才华; 蒋晨曦
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-08-24
Filing date: 2020-08-24
Publication date: 2025-02-14
Anticipated expiration: 2040-08-24
Also published as: CN111772784A

Abstract

The invention discloses an ablation device. The ablation device comprises an ablation catheter body and a control circuit, wherein the tail end of the ablation catheter body is an ablation section, a plurality of electrodes are arranged on the outer surface of the ablation section at intervals, each electrode is connected with the control circuit through a wire, and the control circuit controls the on-off of each electrode. The invention solves the technical problem that the discharge range of the ablation catheter is uncontrollable in the prior art.

Description

Ablation device

Technical Field

The invention relates to the field of medical equipment, in particular to an ablation device.

Background

The catheter ablation technology by using radio frequency energy is one of the most widely used minimally invasive treatment means of arrhythmia at present, and the catheter ablation technology can remove the disease caused by curing the focus by releasing the radio frequency energy locally and conducting impedance heat to cause coagulation necrosis of local deep tissues. The stability of the ablation catheter against the tissue determines one of the important factors of whether the treatment is effective, if the adhesion is poor, the effective contact area of the catheter and the tissue is reduced, more heat is transferred to flowing blood flow, the temperature of deep tissue is lower than the effective ablation temperature, so that only edema of local tissue can be caused, further ablation is affected, and when the adhesion is too strong, rapid temperature rise on one hand can form Jiao Jia at the surface of the tissue and the local part of the electrode, impedance is rapidly increased, and effective transfer of ablation energy is reduced, and on the other hand, risk of embolism and pericardial tamponade is increased. Thus, it is important to maintain the ablation catheter in good abutment during the ablation process.

Although transcatheter radio frequency ablation has achieved good efficacy in many types of arrhythmias, there is still a challenge in terms of atrial fibrillation and ventricular arrhythmias originating from papillary muscles. The main reason for this is that the anatomy of the two sites is complex. The pulmonary vein ridge is thicker muscle sleeve tissue formed by crossing bifurcation phases of the pulmonary vein trunk, the residual pulmonary vein potential on the pulmonary vein ridge is one of important factors causing recurrence or operation failure after atrial fibrillation ablation, the end of a catheter is required to be directly pointed to the ridge part during ablation by an operator, the ridge part is not a flat structure, and the pressure is unstable due to easy sliding during ablation. The ventricular premature beat related to the papillary muscle of the left ventricle is caused by the middle section and the far section of the papillary muscle, an operator needs to press the ablation catheter against the focus part by virtue of the blank, the pressure is applied against the side force, the front end of the catheter is not contacted, the supporting force at the rear part is poor, and the ablation energy cannot effectively enter the tissue.

The ablation catheter in the prior art can only discharge or not discharge in a certain area at the tail end of the catheter, and the discharge range is uncontrollable during discharge, so that the insufficient ablation or the excessive ablation can be caused due to the excessively small or the excessively large electric range. If it is excessive, excessive damage to the papillary muscles may cause ischemic necrosis of the papillary muscles, resulting in dysfunction of the mitral/tricuspid valve, with serious clinical consequences.

Aiming at the problem that the discharge range of the ablation catheter is uncontrollable in the prior art, no effective solution is proposed at present.

Disclosure of Invention

The embodiment of the invention provides an ablation device, which at least solves the technical problem that the discharge range of an ablation catheter is uncontrollable in the prior art.

According to one aspect of the embodiment of the invention, an ablation device is provided, which comprises an ablation catheter main body and a control circuit, wherein the tail end of the ablation catheter main body is an ablation section, a plurality of electrodes are arranged on the outer surface of the ablation section at intervals, each electrode is connected with the control circuit through a wire, and the control circuit controls the on-off of each electrode.

Further, the ablation device further comprises an infusion channel and an infusion hole, wherein the infusion channel is arranged in the ablation catheter body and axially extends out of the ablation catheter body along the ablation catheter body, one or more infusion holes are arranged on part or all of the electrodes, and the infusion holes are communicated with the infusion channel.

Further, the ablation device further comprises an operation handle connected with the ablation catheter body, the control circuit is arranged in the operation handle, the operation handle comprises one or more operation keys, the one or more operation keys are connected with the control circuit, and the one or more operation keys are used for selecting one or more electrodes to conduct on-off switching operation.

Further, the ablation device further comprises a metal grid weaving layer, and a metal grid weaving layer ring layer is arranged inside the outer surface of the ablation catheter body.

Further, the ablation device further comprises a bending part and a bending key, wherein the bending part is arranged inside the ablation catheter body, the bending key is arranged on the operating handle, one end of the bending part is connected with the metal grid weaving layer at a specific distance away from the tail end of the ablation catheter body, and the other end of the bending part is connected with the bending key.

Further, the ablation device also includes a circuit channel disposed within the ablation catheter body for connecting the guidewire along the circuit channel to the control circuit.

Further, the ablation device further comprises a plurality of thermistors, and each thermistor is arranged inside each electrode.

Further, all or part of the main body of the ablation catheter is made of a high-molecular flexible composite material.

Further, the end of the ablation section is provided with an electrode, and the length of the electrode arranged at the end of the ablation section is longer than that of other electrodes.

Further, the plurality of electrodes are uniformly disposed on the ablation segment.

In the embodiment of the invention, as the plurality of electrodes are arranged on the outer surface of the ablation section at intervals, and each electrode is connected with the control circuit through the lead, the on-off of each electrode can be controlled by the control circuit, so that the selective discharge of single or a plurality of electrodes can be realized, the accuracy and the effectiveness of ablation are improved, the technical effect of realizing accurate treatment is achieved, and the technical problem that the discharge range of the ablation catheter is uncontrollable in the prior art is solved.

Drawings

The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this specification, illustrate embodiments of the application and together with the description serve to explain the application and do not constitute a limitation on the application. In the drawings:

FIG. 1 is a schematic illustration of an ablation device in accordance with an embodiment of the invention;

FIG. 2 is a schematic illustration of an ablation device electrode distribution in accordance with an embodiment of the invention;

FIG. 3 is a schematic illustration of an irrigation channel configuration of an ablation device in accordance with an embodiment of the present invention;

FIG. 4 is a schematic cross-sectional view of an ablation device in accordance with an embodiment of the invention;

FIG. 5 is a schematic cross-sectional view of an ablation device in accordance with an embodiment of the invention;

FIG. 6 is a schematic illustration of the overall structure of an ablation device in accordance with an embodiment of the invention;

FIG. 7 is a schematic view of an operation panel according to an embodiment of the present invention;

FIG. 8 is a schematic view of an operation panel according to an embodiment of the present invention;

FIG. 9 is a schematic view of an ablation device in a curved state in accordance with an embodiment of the invention;

fig. 10 is a schematic diagram of an actual application of an ablation device according to an embodiment of the present invention.

Detailed Description

It should be noted that, without conflict, the embodiments of the present application and features of the embodiments may be combined with each other. The application will be described in detail below with reference to the drawings in connection with embodiments.

In order that those skilled in the art will better understand the present invention, a technical solution in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in which it is apparent that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the present invention without making any inventive effort, shall fall within the scope of the present invention.

Example 1

According to an embodiment of the present invention, there is provided an ablation device, fig. 1 is an ablation device according to an embodiment of the present invention, and as shown in fig. 1, the device includes an ablation catheter body 100 and a control circuit 200, the ablation catheter body 100 is terminated by an ablation segment, the outer surface of the ablation segment is provided with a plurality of electrodes 101 distributed at intervals, each electrode 101 is connected with the control circuit 200 through a wire 102, and the on/off of each electrode 101 is controlled by the control circuit 200.

Specifically, as shown in fig. 1, the ablation catheter main body 100, the control circuit 200, the electrodes 101 and the wires 102 are all components of the ablation device of the invention, one end of the ablation catheter main body 100 is a terminal, the other end is connected with the control circuit, the electrodes 101 can be multiple and separated from each other, as shown in reference numerals of fig. 1, 8 electrodes can be provided, which are respectively a No.1 electrode, a No.2 electrode, a No.3 electrode, a No.4 electrode, an 8 electrode, the control circuit 200 can control on/off of each electrode 101, and the circuit control of the control circuit 200 can independently make one electrode 101 or a plurality of electrodes 101 perform selective area discharge, for example, can control on/off of 1 electrode 101, or control on/off of 2 electrodes 101, on/off of other electrodes 101, and the like. Alternatively, the electrode 101 may be annular and/or disk-shaped and fit around the outer surface of the ablation catheter body 100, wherein the electrode 101 may be a platinum electrode.

In addition, the appearance and the manufacturing process of the ablation device are simple, the ablation device can be suitable for large-scale production, can bear the ablation requirements of most common patients, and can meet the ablation characteristics of arrhythmia related to special anatomical parts.

In an alternative embodiment, the ablation segment ends are provided with electrodes 101, the length of the electrodes 101 provided at the ablation segment ends being greater than the length of the other electrodes 101.

Specifically, 1 electrode 101 of the plurality of electrodes 101 may be disposed at the end of the ablation segment, the other electrodes 101 are disposed at other positions of the ablation segment, and the length of the electrode 101 disposed at the end of the ablation segment is longer than that of the other electrodes 101, wherein the electrode 101 disposed at the end of the ablation segment may be disc-shaped, and the other electrodes 101 are ring-shaped, in a specific embodiment, as shown in fig. 2, the length of the electrode 101 disposed at the end of the ablation segment may be set to 4mm, and the length of the other electrodes 101 is 2 mm.

In an alternative embodiment, the plurality of electrodes 101 are uniformly disposed on the ablation segment.

As shown in fig. 2, the intervals between the electrodes 101 may be set to be the same, for example, the intervals between the electrodes 101 may be set to be 1mm, alternatively, the diameter of the ablation catheter body 100 may be set to be 2.5mm to 2.7mm, and it should be noted that the intervals between the electrodes 101 and the diameter of the ablation catheter body 100 may be designed according to the actual situation, and the present invention only provides one possible size design.

In an alternative embodiment, all or part of the ablation catheter body 100 is made of a polymeric flexible composite material.

Specifically, the polymer flexible composite material has plasticity, which is beneficial to realizing various shapes of the ablation catheter main body 100, the ablation catheter main body 100 can be in a straight line shape or can be bent into other shapes, and the polymer flexible composite material can enable polyurethane to be selected.

In an alternative embodiment, as shown in fig. 3 and 4, the ablation device further comprises an irrigation channel 103 and an irrigation hole 104, wherein the irrigation channel 103 is disposed in the ablation catheter body 100 and extends out of the ablation catheter body 100 along the axial direction of the ablation catheter body 100, and one or more irrigation holes 104 are disposed on part or all of the electrodes 101, and the irrigation holes 104 are in communication with the irrigation channel 103.

In particular, one or more perfusion holes 104 may be provided in each electrode 101, and these perfusion holes 104 are in communication with the perfusion channel 103, and saline or other liquid material may enter the body through the perfusion channel 103 and the perfusion holes 104. Optionally, a hydrophobic coating may be applied within the irrigation channel 103 to prevent shorting of the electrode 101.

In an alternative embodiment, as shown in fig. 4 and 5, the ablation device includes a circuit channel 105 in addition to the irrigation channel 104, the circuit channel 105 being disposed within the ablation catheter body 100 for connecting the lead 102 with the control circuit 200 along the circuit channel 105.

In an alternative embodiment, as shown in fig. 6, the ablation device further includes an operation handle 300 connected to the ablation catheter body 100, and the control circuit 200 may be disposed in the operation handle 300, where the operation handle 300 includes one or more operation keys, and the one or more operation keys are connected to the control circuit 200, and are used to select one or more electrodes 101 for performing an on-off switching operation.

Specifically, the circuit information can be input into the control circuit 200 through the operation key on the operation handle 300, and the discharge mode of the electrode 101 can be controlled through the transmission of the lead 102, so that the selective discharge of the ablation device is realized, and the accurate discharge is realized, as shown in fig. 6, the upper side of the tail part of the operation handle 300 is an extended perfusion channel 103, the lower side is an electrode tail wire, and the operation handle 300 can be connected with the three-dimensional mapping system and the radio frequency ablation instrument through the electrode tail wire at the tail part.

Specifically, the discharge modes of the electrodes 101 may include a monopolar discharge mode in which one electrode 101 serves as a positive electrode and forms a circuit with a negative electrode patch attached to a subject, and a bipolar discharge mode in which two electrodes 101 serve as positive and negative electrodes and form a circuit therebetween. In addition to the discharge mode of the above 2, there may be other modes, for example, selecting 2 electrodes 101 that are not adjacent to each other to discharge, selecting a plurality of pairs of electrodes 101 to discharge, and the like.

Specifically, an operation panel shown in fig. 7 and 8 may be provided on the operation handle 300, an operation key is provided on the operation panel, a shaded square is an operation key, a monopolar discharge selection mode is provided above the operation panel, a bipolar discharge selection mode is provided below the operation panel, when the slider is in the position shown in fig. 7, a monopolar discharge mode is selected by default, when the slider is in the monopolar discharge mode, the third electrode is used as the positive electrode for discharging, when the slider is in the monopolar discharge mode, when the slider is not in the "no" position, as shown in fig. 8, the bipolar discharge mode is selected, and when the slider is in the position shown in fig. 8, the first electrode and the third electrode are used as the positive electrode and the negative electrode for discharging. Here, the operation panel and the operation key may be set according to actual situations, and the present invention only provides one example, and the setting of the operation panel and the operation key is only required to satisfy the mode selection requirement.

In an alternative embodiment, the ablation device further comprises a metal mesh braid disposed inside the outer surface of the ablation catheter body.

Specifically, the metal mesh braid may be a stainless steel mesh layer, which may ensure the stability and torque of the plasticity of the ablation catheter body 100.

In an alternative embodiment, as shown in fig. 6, the ablation device further includes a bending member and a bending key 301, the bending member is disposed inside the ablation catheter body 100, the bending key 301 is disposed on the operation handle 300, one end of the bending member is connected to the metal mesh braid at a specific distance from the distal end of the ablation catheter body 100, and the other end of the bending member is connected to the bending key 301.

Specifically, the ablation catheter used in the prior art is shaped into a curve, and is not suitable for local ablation at a specific anatomical position, while the invention can realize the diversity of the shape of the ablation catheter main body by arranging the bending part and the bending key 301, and optionally, the bending part can be a bending steel wire and can be arranged at a position 7-8cm away from the tail end of the ablation catheter main body 100, the bending key 301 can be a bending knob, and one end of the bending part is connected with the inner wall of the ablation catheter main body 100, and one end of the bending part is connected with the bending key 301, so that the ablation catheter main body 100 can be bent according to rotation when the bending key 301 is rotated. As shown in FIG. 9, in the case where the ablation catheter body 100 is about 135-140mm long and its in-vivo length deep into the sheath is 115-120mm, the maximum bending diameter of the ablation catheter body 100 may reach 45-55 mm.

Specifically, the length of the metal mesh braid may extend from the location where the bent wire is disposed up to the operating handle 300.

In an alternative embodiment, the ablation device further comprises a plurality of thermistors, each electrode 101 having a thermistor disposed therein.

Specifically, each electrode 101 is also provided with a thermistor inside, so that a temperature sensing function during ablation can be realized.

In a specific embodiment, as shown in fig. 10, the ventricular premature beat of the middle section of the left papillary muscle of the left ventricle is shown in fig. 10, when the end of the ablation catheter body 100 is abutted against the root of the papillary muscle, the end of the ablation catheter body 100 can be directly contacted with the papillary muscle, and the 4 th to 5 th electrodes of the end of the ablation catheter body 100 can be selectively discharged, so that the ablation treatment can be directly carried out on the origin site of the ventricular premature beat.

The foregoing embodiment numbers of the present invention are merely for the purpose of description, and do not represent the advantages or disadvantages of the embodiments.

In the foregoing embodiments of the present invention, the descriptions of the embodiments are emphasized, and for a portion of this disclosure that is not described in detail in this embodiment, reference is made to the related descriptions of other embodiments.

It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of exemplary embodiments according to the present application. As used herein, the singular is also intended to include the plural unless the context clearly indicates otherwise, and furthermore, it is to be understood that the terms "comprises" and/or "comprising" when used in this specification are taken to specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof.

The relative arrangement of the components and steps, numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present invention unless it is specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective parts shown in the drawings are not drawn in actual scale for convenience of description. Techniques, methods, and apparatus known to one of ordinary skill in the relevant art may not be discussed in detail, but should be considered part of the specification where appropriate. In all examples shown and discussed herein, any specific values should be construed as merely illustrative, and not a limitation. Thus, other examples of the exemplary embodiments may have different values. It should be noted that like reference numerals and letters refer to like items in the following figures, and thus once an item is defined in one figure, no further discussion thereof is necessary in subsequent figures.

In the description of the present invention, it should be understood that the azimuth or positional relationships indicated by the azimuth terms such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal", and "top, bottom", etc., are generally based on the azimuth or positional relationships shown in the drawings, and are merely for convenience of describing the present invention and simplifying the description, and these azimuth terms do not indicate and imply that the apparatus or elements referred to must have a specific azimuth or be constructed and operated in a specific azimuth, and thus should not be construed as limiting the scope of the present invention, and the azimuth terms "inside and outside" refer to inside and outside with respect to the outline of each component itself.

Spatially relative terms, such as "above," "upper" and "upper surface," "above" and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations in use or operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements described as "above" or "over" other devices or structures would then be oriented "below" or "beneath" the other devices or structures. Thus, the process is carried out, the exemplary term "above" may be included. Upper and lower. Two orientations below. The device may also be positioned in other different ways (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.

In addition, the terms "first", "second", etc. are used to define the components, and are only for convenience of distinguishing the corresponding components, and the terms have no special meaning unless otherwise stated, and therefore should not be construed as limiting the scope of the present invention.

The foregoing is merely a preferred embodiment of the present invention and it should be noted that modifications and adaptations to those skilled in the art may be made without departing from the principles of the present invention, which are intended to be comprehended within the scope of the present invention.

Claims

1. An ablation device, characterized in that it comprises an ablation catheter body and a control circuit, wherein the end of the ablation catheter body is an ablation segment, and a plurality of electrodes distributed at intervals are arranged on the outer surface of the ablation segment, each of the electrodes is connected to the control circuit through a wire, and the control circuit controls the on and off of each of the electrodes;

The ablation device also includes an operating handle connected to the ablation catheter body, the control circuit is arranged in the operating handle, the operating handle includes one or more operating keys, the one or more operating keys are connected to the control circuit, and the one or more operating keys are used to select one or more of the electrodes for on-off switching operation; the lower side of the tail of the operating handle is an electrode tail wire, and the operating handle is connected to the three-dimensional mapping system and the radio frequency ablation instrument through the electrode tail wire at its tail. The discharge mode of the electrode includes a unipolar discharge mode and a bipolar discharge mode. The unipolar discharge mode refers to a discharge mode in which a certain electrode is used as the positive electrode to form a circuit with the negative electrode patch attached to the subject; the bipolar discharge mode refers to a discharge mode in which a certain two electrodes are used as the positive electrode. The electrodes are used as positive and negative poles to form a discharge mode of a loop, an operation panel is provided on the operation handle, and operation keys are provided on the operation panel. The shaded squares in the operation panel are the operation keys. The upper part of the operation panel is a unipolar discharge selection mode, and the lower part is a bipolar discharge selection mode. When the slider in the bipolar discharge mode is at the "none" position, the unipolar discharge mode is selected by default. When the slider in the unipolar discharge mode is selected as 3, the third electrode is used as the positive pole for discharge; when the slider in the bipolar discharge mode is not at the "none" position, the bipolar discharge mode is selected. When the slider in the unipolar discharge mode is at the position of 3 and the slider in the bipolar discharge mode is at the position of 1, the first electrode and the third electrode are used as the positive and negative poles for discharge;

The ablation device further comprises a metal mesh braided layer, and the metal mesh braided layer is arranged inside the outer surface of the ablation catheter body;

The ablation device also includes a bending component and a bending key. The bending component is arranged inside the ablation catheter body, and the bending key is arranged on the operating handle. One end of the bending component is connected to the metal mesh braided layer at a specific distance from the end of the ablation catheter body, and the other end of the bending component is connected to the bending key. The bending key is a bending knob, and the bending component is a bending wire. When the bending key is rotated, the ablation catheter body will bend according to the rotation. The length of the metal mesh braided layer extends from the position where the bending wire is set to the operating handle.

2. The ablation device according to claim 1 is characterized in that the ablation device also includes an perfusion channel and a perfusion hole, the perfusion channel is arranged in the ablation catheter body and extends out of the ablation catheter body axially along the ablation catheter body; one or more perfusion holes are arranged on some or all of the electrodes, and the perfusion holes are connected to the perfusion channel.

3. The ablation device according to claim 1 or 2, characterized in that the ablation device further comprises a circuit channel, wherein the circuit channel is arranged in the ablation catheter body and is used to connect the wire to the control circuit along the circuit channel.

4. The ablation device according to claim 1 or 2, characterized in that the ablation device further comprises a plurality of thermistors, wherein the thermistor is disposed inside each of the electrodes.

5. The ablation device according to claim 1 or 2, characterized in that all or part of the ablation catheter body is made of a polymer flexible composite material.

6. The ablation device according to claim 1 or 2, characterized in that the electrode is provided at the end of the ablation segment, and the length of the electrode provided at the end of the ablation segment is greater than the length of the other electrodes.

7. The ablation device according to claim 1 or 2, characterized in that the plurality of electrodes are evenly arranged on the ablation segment.