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CN111684263A - 血液分析系统、血液分析仪、血液分析方法及存储介质 - Google Patents

血液分析系统、血液分析仪、血液分析方法及存储介质 Download PDF

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Publication number
CN111684263A
CN111684263A CN201980008250.0A CN201980008250A CN111684263A CN 111684263 A CN111684263 A CN 111684263A CN 201980008250 A CN201980008250 A CN 201980008250A CN 111684263 A CN111684263 A CN 111684263A
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blood
blood analysis
test sample
optical signals
analysis method
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叶波
祁欢
郑文波
叶燚
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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Shenzhen Mindray Bio Medical Electronics Co Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4915—Blood using flow cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G01N2015/018—Platelets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1402—Data analysis by thresholding or gating operations performed on the acquired signals or stored data

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  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
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Abstract

一种血液分析系统(1，2)、血液分析仪、血液分析方法及存储介质，血液分析方法包括：获取来自血液样本的一被测试样的至少两种光学信号，被测试样中的红细胞被溶解，被测试样中的血细胞被荧光染色，至少两种光学信号包括散射光信号和/或荧光信号(301)；基于至少两种光学信号生成被测试样的散点图(S303)；基于至少两种光学信号在散点图中识别一预设区域(S305)；基于预设区域得到血液样本中血小板亚群的检测数据(S307)。

Description

PCT国内申请，说明书已公开。

Claims (52)

  1. PCT国内申请，权利要求书已公开。
CN201980008250.0A 2018-04-28 2019-04-26 血液分析系统、血液分析仪、血液分析方法及存储介质 Pending CN111684263A (zh)

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CN2018085199 2018-04-28
CNPCT/CN2018/085199 2018-04-28
PCT/CN2019/084685 WO2019206311A1 (zh) 2018-04-28 2019-04-26 血液分析系统、血液分析仪、血液分析方法及存储介质

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CN110249223B (zh) * 2017-02-17 2020-10-20 深圳迈瑞生物医疗电子股份有限公司 血液细胞分析方法及血液细胞分析仪
CN118347920A (zh) * 2020-05-14 2024-07-16 深圳迈瑞生物医疗电子股份有限公司 样本分析仪及样本分析方法
CN111781168B (zh) * 2020-06-17 2023-06-13 迈克医疗电子有限公司 红细胞碎片识别区域的调整方法、装置、设备和介质
CN114252386A (zh) * 2020-09-23 2022-03-29 深圳迈瑞生物医疗电子股份有限公司 样本检测方法和样本分析仪
CN115219392A (zh) * 2021-04-14 2022-10-21 深圳迈瑞生物医疗电子股份有限公司 样本分析仪和样本分析方法
CN116298348A (zh) * 2023-05-17 2023-06-23 深圳迈瑞动物医疗科技股份有限公司 一种物种用血液分析装置及方法

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