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CN111631762B - Biopsy instrument for research of pathology department and use method thereof - Google Patents

Biopsy instrument for research of pathology department and use method thereof Download PDF

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Publication number
CN111631762B
CN111631762B CN202010583910.2A CN202010583910A CN111631762B CN 111631762 B CN111631762 B CN 111631762B CN 202010583910 A CN202010583910 A CN 202010583910A CN 111631762 B CN111631762 B CN 111631762B
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wall
fixedly connected
fixed block
block
housing
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CN111631762A (en
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陈咏梅
王静
沈长久
陈林
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Second Peoples Hospital of Nantong
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Second Peoples Hospital of Nantong
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention discloses a biopsy instrument for research of pathology department and a use method thereof, and relates to the technical field of biopsy, wherein a clamping part comprises a rotating arm hinged on the inner wall of a shell, a connecting plate is hinged at the end part of the rotating arm, a through groove is formed at the upper end of the connecting plate, the connecting plate is slidably connected with a supporting plate through the through groove, a fixed block is fixedly connected with the surface of the rotating arm, a chute is formed at the lower end of the fixed block, the fixed block is slidably connected with the clamping block through the chute, and the biopsy instrument further comprises a transmission part, and when the clamping block rotates along with the fixed block, the clamping block is driven to extend or stretch into the chute along the wall of the chute under the action of the transmission part. The invention has the advantages that through the cooperation between the structures, the abrasion to the stomach wall in the patient is reduced; 2. the sampling time is reduced, and the pain of a patient is relieved; 3. the phenomenon that the living tissue automatically slides out of the sampling needle is avoided; 4. the living tissue is more easily penetrated by the sampling needle.

Description

一种病理科研究用活体组织检查器械及其使用方法Biopsy instrument for pathological research and method of use thereof

技术领域technical field

本发明涉及活体组织检查技术领域,具体为一种病理科研究用活体组织检查器械。The invention relates to the technical field of biopsy, in particular to a biopsy instrument for pathology research.

背景技术Background technique

活体组织检查,是从病人身上可疑的病变组织上,取下一小块组织,用以协助临床医生确定疾病的诊断,在取样时通常是先使用切割刀对活体组织进行切割处理之后,使用活检钳对活体组织进行夹取,之后将活体组织转移到光学显微镜下进行观察。Biopsy is to remove a small piece of tissue from a patient's suspicious diseased tissue to assist clinicians in determining the diagnosis of the disease. When sampling, the biopsy is usually used after cutting the living tissue with a cutting knife. The forceps grasp the living tissue, and then transfer the living tissue to an optical microscope for observation.

但现有技术中在使用活检钳对活体组织进行夹取时,由于活检钳类似于剪刀状,继而为了保证位于患者体内胃壁的活体组织可在活检钳两个夹头的夹持路径内,通常需要将活检钳的两个夹头抵接到患者体内胃壁,方可顺利进行取样,从而在抵接到患者体内胃壁后,随着活检钳两个夹头转动合拢的过程,活检钳的两个夹头容易对患者体内的胃壁造成摩损,进而引发患者的不适。However, in the prior art, when biopsy forceps are used to clamp living tissue, since the biopsy forceps are similar to scissors, in order to ensure that the living tissue located on the stomach wall of the patient can be within the gripping path of the two chucks of the biopsy forceps, usually The two chucks of the biopsy forceps need to abut against the stomach wall in the patient's body before sampling can be carried out smoothly, so that after touching the stomach wall in the patient's body, as the two chucks of the biopsy forceps rotate and close, the two chucks of the biopsy forceps The collet is easy to cause friction to the stomach wall in the patient's body, thereby causing discomfort to the patient.

发明内容Contents of the invention

本发明的目的在于提供一种病理科研究用活体组织检查器械,具备了一、减少了对患者体内胃壁造成的摩损;二、减少取样时间,减轻了患者的疼痛;三、避免发生活体组织自滑出取样针的现象;四、活体组织更容易被取样针穿刺的效果,解决了现有技术中活检钳在夹取活体组织时,容易对患者体内的胃壁造成摩损的问题。The object of the present invention is to provide a biopsy instrument for pathological research, which has the advantages of firstly reducing the wear and tear on the stomach wall of the patient; secondly reducing the sampling time and reducing the pain of the patient; The phenomenon that the tissue self-slips out of the sampling needle; 4. The effect that the living tissue is more easily punctured by the sampling needle, which solves the problem that the biopsy forceps in the prior art easily cause friction to the stomach wall in the patient's body when clamping the living tissue.

为实现上述目的,本发明提供如下技术方案:一种病理科研究用活体组织检查器械,包括用于活体组织检查的取样器,所述取样器包括壳体,所述壳体的内壁设置有两个夹持部。In order to achieve the above object, the present invention provides the following technical solutions: a biopsy instrument for pathological research, including a sampler for biopsy, the sampler includes a housing, the inner wall of the housing is provided with two a clamping part.

所述夹持部包括铰接在所述壳体内壁的转臂,所述转臂的端部铰接有连板,所述连板的上端开设有通槽,所述连板通过通槽滑动连接有支撑板,所述转臂的表面固定连接有固定块,所述固定块的下端开设有滑槽,所述固定块通过所述滑槽滑动连接有夹块,还包括传动部,在所述夹块跟随所述固定块转动时,通过所述传动部的作用,带动所述夹块沿所述滑槽的槽壁,作相对于所述固定块伸出或伸入运动。The clamping part includes a rotating arm hinged on the inner wall of the housing, the end of the rotating arm is hinged with a connecting plate, the upper end of the connecting plate is provided with a through groove, and the connecting plate is slidably connected with a connecting plate through the through groove. The support plate, the surface of the rotating arm is fixedly connected with a fixed block, the lower end of the fixed block is provided with a chute, and the fixed block is slidably connected with a clip block through the chute, and also includes a transmission part. When the block rotates following the fixed block, the action of the transmission part drives the clamping block along the groove wall of the chute to move out or in relative to the fixed block.

所述取样器还包括用于驱动所述支撑板上下移动的驱动部。The sampler also includes a driving part for driving the support plate to move up and down.

优选的,所述传动部包括穿设在所述固定块内壁的限位杆,所述限位杆的端部与所述夹块的表面固定连接,所述限位杆的杆臂套设有弹簧一,所述弹簧一的两端部分别与所述固定块的内壁和所述夹块的表面固定连接,所述固定块靠近其上端的内壁固定安装有绕线轮,所述绕线轮的表面缠绕有绳一和绳二,所述绳一远离所述绕线轮的一端与所述连板靠近所述支撑板的一端固定连接,所述绳二远离所述绕线轮的一端与所述夹块的表面固定连接。Preferably, the transmission part includes a limit rod pierced on the inner wall of the fixed block, the end of the limit rod is fixedly connected with the surface of the clamp block, and the arm of the limit rod is covered with Spring one, the two ends of the spring one are respectively fixedly connected to the inner wall of the fixed block and the surface of the clamp block, and the inner wall of the fixed block near its upper end is fixedly equipped with a winding wheel, and the winding wheel Rope 1 and Rope 2 are wound on the surface of Rope 1, the end of Rope 1 away from the reel is fixedly connected to the end of the connecting plate close to the support plate, and the end of Rope 2 away from the reel is connected to The surfaces of the clamping blocks are fixedly connected.

优选的,所述驱动部包括与所述支撑板固定连接的拉杆,所述壳体的顶部开设有与所述拉杆滑动连接的通孔,所述拉杆的上端固定连接有拉块,所述拉杆的杆臂套设有弹簧二,所述弹簧二的两端部分别与所述壳体的内壁和所述支撑板的表面固定连接。Preferably, the drive part includes a pull rod fixedly connected to the support plate, a through hole slidably connected to the pull rod is opened on the top of the housing, a pull block is fixedly connected to the upper end of the pull rod, and the pull rod The lever arm is covered with a spring 2, and the two ends of the spring 2 are respectively fixedly connected with the inner wall of the housing and the surface of the support plate.

优选的,所述壳体内设置有取样针,并且所述取样针位于两个所述夹持部之间。Preferably, a sampling needle is arranged in the housing, and the sampling needle is located between the two clamping parts.

优选的,所述取样针的端部固定连接有转轴一,所述转轴一的端部转动连接在所述壳体的内壁,所述壳体的内壁固定连接有安装板,所述安装板的板壁转动连接有转轴二,所述转轴一的轴臂和所述转轴二的轴臂均固定连接有锥形齿轮,两个所述锥形齿轮相啮合,所述转轴二的轴臂还固定连接有齿轮,任意一所述支撑板的上表面固定连接有与所述齿轮啮合的齿条板。Preferably, the end of the sampling needle is fixedly connected with a rotating shaft 1, and the end of the rotating shaft 1 is rotatably connected with the inner wall of the housing, and the inner wall of the housing is fixedly connected with a mounting plate, and the mounting plate The plate wall is rotatably connected with the shaft two, the shaft arm of the shaft one and the shaft arm of the shaft two are fixedly connected with a bevel gear, the two bevel gears are meshed, and the shaft arm of the second shaft is also fixedly connected There are gears, and the upper surface of any one of the support plates is fixedly connected with a rack plate meshing with the gears.

优选的,所述夹块的下端开设有交错槽,并且两个所述夹块通过所述交错槽可相互交叉。Preferably, the lower ends of the clamping blocks are provided with staggered grooves, and two clamping blocks can cross each other through the staggered grooves.

此外,本发明还提供一种病理科研究用活体组织检查器械的使用方法,包括以下步骤:In addition, the present invention also provides a method for using a biopsy instrument for pathology research, including the following steps:

S1:在对所述活体组织进行切割处理之后,所述活体组织自掉落至患者体内的胃壁处,随后将所述壳体伸入至患者的体内,并且在伸入后,所述固定块的端部不与患者体内的胃壁相接触;S1: After cutting the living tissue, the living tissue falls into the stomach wall of the patient, and then the shell is inserted into the patient's body, and after the insertion, the fixing block The end of the tube does not come into contact with the stomach wall in the patient;

S2:保持所述壳体的位置,随后通过操纵所述驱动部,带动两个所述连板上移,通过两个所述连板上移,即可使得所述夹块在跟随所述固定块转动的同时,向患者体内胃壁方向移动,从而保证了所述夹块的夹持路径可顺利的夹持到位于患者体内胃壁的所述活体组织;S2: Keep the position of the housing, and then drive the two connecting plates to move by manipulating the driving part. By moving the two connecting plates, the clamping block can follow the fixed While the block rotates, it moves toward the gastric wall in the patient's body, thereby ensuring that the clamping path of the clamping block can smoothly clamp to the living tissue located on the gastric wall in the patient's body;

S3:取样完成后,将所述壳体移出人体,并且将所述活体组织转移到光学显微镜下进行观察即可。S3: After the sampling is completed, the housing is removed from the human body, and the living tissue is transferred to an optical microscope for observation.

与现有技术相比,本发明的有益效果如下:Compared with the prior art, the beneficial effects of the present invention are as follows:

一、本发明中夹块在跟随固定块转动的同时,可向患者体内胃壁方向移动,使得固定块和夹块均可在不对患者体内胃壁造成摩损的情况下,通过夹块的移动,来保证夹块的夹持路径可顺利的夹持到位于患者体内胃壁上的活体组织,从而相对现有技术中,通过类似剪刀状的活检钳取样时,为了保证位于患者体内胃壁上的活体组织可在活检钳的夹持路径内,通常需要将活检钳的端部抵接到患者体内胃壁,方可顺利进行取样,进而本发明减少了对患者体内胃壁造成的摩损。1. In the present invention, the clamping block can move toward the stomach wall in the patient's body while following the rotation of the fixed block, so that both the fixing block and the clamping block can be moved through the movement of the clamping block without causing friction to the gastric wall in the patient's body. Ensure that the clamping path of the clamp block can be smoothly clamped to the living tissue located on the stomach wall in the patient's body, so that compared with the prior art, when sampling through scissor-like biopsy forceps, in order to ensure that the living tissue located on the stomach wall in the patient's body can be In the clamping path of the biopsy forceps, it is usually necessary to abut the end of the biopsy forceps against the stomach wall of the patient in order to take a sample smoothly, and the present invention reduces the friction caused to the stomach wall of the patient.

二、本发明可将活体组织逐个串在取样针上,从而可以在壳体一次进入人体后,即可完成多次取样,减少取样时间,进而间接减轻了患者的疼痛。2. The present invention can string living tissues on the sampling needle one by one, so that after the shell enters the human body once, multiple sampling can be completed, the sampling time is reduced, and the patient's pain is indirectly relieved.

三、本发明在活体组织被取样针穿刺的过程中,通过两个连板向相对方向移动,对活体组织的运动轨迹进行限制并进行挤压,继而相对于现有技术中,在直接推动活体组织时,因活体组织本身具备的柔软性,容易导致活体组织的中心部难以被取样针完整的穿刺,从而导致被取样针穿刺后的活体组织,活体组织与取样针之间的紧密性不佳,进而发生活体组织自滑出取样针的现象。3. In the process of the living tissue being punctured by the sampling needle, the present invention restricts and squeezes the trajectory of the living tissue through two connecting plates moving in opposite directions, and then directly pushes the living tissue During the tissue, due to the softness of the living tissue itself, it is easy to make the center of the living tissue difficult to be completely punctured by the sampling needle, resulting in poor tightness between the living tissue and the sampling needle after being punctured by the sampling needle , and then the living tissue self-slips out of the sampling needle.

四、本发明通过取样针转动并配合活体组织向取样针方向移动,对活体组织实现一个切削与钻进的过程,进而使得活体组织更容易被取样针穿刺。4. The present invention implements a cutting and drilling process on the living tissue by rotating the sampling needle and cooperating with the living tissue to move toward the sampling needle, so that the living tissue is more easily punctured by the sampling needle.

附图说明Description of drawings

图1为本发明结构的第一状态图且作为主视图;Fig. 1 is the first state figure of structure of the present invention and as front view;

图2为本发明对应图1中局部结构的正视剖视图;Fig. 2 is the front sectional view of the local structure corresponding to Fig. 1 of the present invention;

图3为本发明对应图1中连板和支撑板结构的侧视图;Fig. 3 is a side view of the present invention corresponding to the connecting plate and supporting plate structure in Fig. 1;

图4为本发明对应图1中夹块结构的侧视图;Fig. 4 is a side view of the clamping block structure corresponding to Fig. 1 in the present invention;

图5为本发明结构的第二状态图;Fig. 5 is the second state diagram of structure of the present invention;

图6为本发明结构的第三状态图;Fig. 6 is the third state diagram of structure of the present invention;

图7为本发明结构的第四状态图;Fig. 7 is the fourth state diagram of structure of the present invention;

图8为本发明对应图7中固定块和夹块结构的俯视图;Fig. 8 is a top view of the present invention corresponding to the fixed block and clamping block structure in Fig. 7;

图9为本发明结构的第五状态图。Fig. 9 is a fifth state diagram of the structure of the present invention.

图中:1-活体组织、2-壳体、3-转臂、4-连板、5-支撑板、6-固定块、7-夹块、8-限位杆、9-弹簧一、10-绕线轮、11-绳一、12-绳二、13-拉杆、14-拉块、15-弹簧二、16-取样针、17-转轴一、18-安装板、19-转轴二、20-锥形齿轮、21-齿轮、22-齿条板、23-交错槽。In the figure: 1-living tissue, 2-housing, 3-rotating arm, 4-connecting plate, 5-supporting plate, 6-fixing block, 7-clamping block, 8-limiting rod, 9-spring one, 10 -winding wheel, 11-rope 1, 12-rope 2, 13-pull rod, 14-pulling block, 15-spring 2, 16-sampling needle, 17-rotating shaft 1, 18-installation plate, 19-rotating shaft 2, 20 - bevel gear, 21 - gear, 22 - rack plate, 23 - staggered groove.

具体实施方式Detailed ways

下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

请参阅图1至图9,本发明提供一种技术方案:一种病理科研究用活体组织检查器械,包括用于活体组织1检查的取样器,取样器包括壳体2,壳体2的内壁设置有两个夹持部,夹持部包括铰接在壳体2内壁的转臂3,转臂3的端部铰接有连板4,连板4的上端开设有通槽,连板4通过通槽滑动连接有支撑板5,转臂3的表面固定连接有固定块6,固定块6的下端开设有滑槽,固定块6通过滑槽滑动连接有夹块7,还包括传动部,在夹块7跟随固定块6转动时,通过传动部的作用,带动夹块7沿滑槽的槽壁,作相对于固定块6伸出或伸入运动,取样器还包括用于驱动支撑板5上下移动的驱动部,在对活体组织1进行切割处理之后,活体组织1自掉落至患者体内的胃壁处,随后将壳体2伸入至患者的体内并如图1所示,此时固定块6的下端不与患者体内的胃壁相接触,继而减少了固定块6在转动时,对患者体内胃壁造成的摩损,然后保持壳体2的位置,并且通过驱动部的运作,带动两个支撑板5上移,通过两个支撑板5上移,带动两个连板4上移,通过两个连板4上移并经连板4与转臂3之间的铰接关系,带动两个转臂3均以各自与壳体2之间的铰接点为圆心进行转动,通过两个转臂3转动,带动两个固定块6转动,通过两个固定块6的下端向相对方向转动,继而对活体组织1提供夹持力,上述过程中,通过两个支撑板5上移并经转臂3转动限制,带动两个连板4向相对方向移动,通过两个连板4向相对方向移动并经传动部的传动,使得夹块7在跟随固定块6转动的同时,向靠近患者体内胃壁的方向移动并至图5所示状态,此时即可对活体组织1进行夹持,本发明中夹块7在跟随固定块6转动的同时,可向患者体内胃壁方向移动,使得固定块6和夹块7均可在不对患者体内胃壁造成摩损的情况下,通过夹块7的移动,来保证夹块7的夹持路径可顺利的夹持到位于患者体内胃壁的活体组织1,从而相对现有技术中,通过类似剪刀状的活检钳取样时,为了保证位于患者体内胃壁的活体组织1可在活检钳两个夹头的夹持路径内,通常需要将活检钳的两个夹头抵接到患者体内胃壁,方可顺利进行取样,进而本发明减少了对患者体内胃壁造成的摩损。Please refer to Fig. 1 to Fig. 9, the present invention provides a kind of technical scheme: a kind of biopsy instrument for pathology research, comprises the sampler that is used for biopsy 1 examination, sampler comprises housing 2, the inner wall of housing 2 Two clamping parts are provided, and the clamping part includes a rotating arm 3 hinged on the inner wall of the housing 2, the end of the rotating arm 3 is hinged with a connecting plate 4, the upper end of the connecting plate 4 is provided with a through groove, and the connecting plate 4 passes through the connecting plate 4. The groove is slidably connected with a support plate 5, and the surface of the rotating arm 3 is fixedly connected with a fixed block 6, and the lower end of the fixed block 6 is provided with a chute, and the fixed block 6 is slidably connected with a clamping block 7 through the chute, and also includes a transmission part. When the block 7 rotates with the fixed block 6, through the action of the transmission part, the clamp block 7 is driven to extend or extend relative to the fixed block 6 along the groove wall of the chute. The moving drive part, after the living tissue 1 is cut, the living tissue 1 falls to the stomach wall of the patient, and then the housing 2 is inserted into the patient's body as shown in Figure 1, at this time the fixed block The lower end of 6 is not in contact with the stomach wall in the patient's body, thereby reducing the friction caused by the fixed block 6 to the stomach wall in the patient's body when rotating, and then maintaining the position of the housing 2, and driving the two supports through the operation of the driving part The plate 5 moves up, moves up through the two supporting plates 5, drives the two connecting plates 4 to move up, moves up through the two connecting plates 4 and through the hinged relationship between the connecting plates 4 and the rotating arm 3, drives the two connecting plates 4 The arms 3 all rotate with the hinge points between them and the housing 2 as the center of circle, and the rotation of the two rotating arms 3 drives the two fixed blocks 6 to rotate, and the lower ends of the two fixed blocks 6 rotate to the opposite direction, and then The living tissue 1 provides the clamping force. During the above process, the two supporting plates 5 move up and are limited by the rotation of the rotating arm 3, driving the two connecting plates 4 to move in the opposite direction, and the two connecting plates 4 move in the opposite direction and Driven by the transmission part, the clamping block 7 moves toward the stomach wall in the patient's body while following the rotation of the fixed block 6 and reaches the state shown in Figure 5, at which point the living tissue 1 can be clamped. The clamping block 7 can move toward the stomach wall in the patient's body while following the rotation of the fixing block 6, so that both the fixing block 6 and the clamping block 7 can move through the clamping block 7 without causing friction to the stomach wall in the patient's body. Ensure that the clamping path of the clamp block 7 can be smoothly clamped to the living tissue 1 located on the stomach wall in the patient's body, so that compared with the prior art, when sampling through scissor-like biopsy forceps, in order to ensure that the living tissue 1 located on the stomach wall in the patient's body In the clamping path of the two chucks of the biopsy forceps, it is usually necessary to abut the two chucks of the biopsy forceps against the stomach wall in the patient's body, so that sampling can be carried out smoothly, and the invention reduces the friction caused to the stomach wall in the patient's body .

进一步的,为了使得两个连板4在向相对方向移动时,夹块7可在跟随固定块6转动的同时,向患者体内胃壁方向移动,本发明中的传动部具体包括以下部件,传动部包括穿设在固定块6内壁的限位杆8,限位杆8的端部与夹块7的表面固定连接,限位杆8的杆臂套设有弹簧一9,弹簧一9的两端部分别与固定块6的内壁和夹块7的表面固定连接,固定块6靠近其上端的内壁固定安装有绕线轮10,绕线轮10的表面缠绕有绳一11和绳二12,绳一11远离绕线轮10的一端与连板4靠近支撑板5的一端固定连接,绳二12远离绕线轮10的一端与夹块7的表面固定连接,通过两个连板4向相对方向移动,使得绳一11拉动绕线轮10转动,通过绕线轮10转动,对绳二12进行放线并利用弹簧一9的弹性恢复力,即可使得夹块7在跟随固定块6转动的同时,向患者体内胃壁方向移动。Furthermore, in order to make the two connecting plates 4 move in opposite directions, the clamp block 7 can move toward the stomach wall in the patient’s body while following the rotation of the fixed block 6, the transmission part in the present invention specifically includes the following components, the transmission part Including the limit rod 8 that is installed on the inner wall of the fixed block 6, the end of the limit rod 8 is fixedly connected with the surface of the clamp block 7, the lever arm of the limit rod 8 is provided with a spring one 9, and the two ends of the spring one 9 The parts are fixedly connected with the inner wall of the fixed block 6 and the surface of the clamp block 7 respectively, and the inner wall of the fixed block 6 near its upper end is fixedly equipped with a reel 10, and the surface of the reel 10 is wound with a rope one 11 and a rope two 12, and the rope The end of one 11 away from the reel 10 is fixedly connected with the end of the connecting plate 4 close to the support plate 5, the end of the rope two 12 away from the reel 10 is fixedly connected with the surface of the clamping block 7, through the two connecting plates 4 to the opposite direction Move, so that the rope one 11 pulls the reel 10 to rotate, and through the rotation of the reel 10, the rope two 12 is released and the elastic restoring force of the spring one 9 is used to make the clamping block 7 follow the rotation of the fixed block 6. Simultaneously, move towards the stomach wall inside the patient.

进一步的,为了带动两个支撑板5上移,本发明中的驱动部具体包括以下部件,驱动部包括与支撑板5固定连接的拉杆13,壳体2的顶部开设有与拉杆13滑动连接的通孔,拉杆13的上端固定连接有拉块14,拉杆13的杆臂套设有弹簧二15,弹簧二15的两端部分别与壳体2的内壁和支撑板5的表面固定连接,通过上拉拉块14并经拉杆13,即可带动两个支撑板5上移,并且在松开拉块14时,可利用弹簧二15的弹性恢复力,即可使得两个支撑板5下移。Further, in order to drive the two support plates 5 to move upward, the driving part in the present invention specifically includes the following components. The drive part includes a pull rod 13 fixedly connected to the support plate 5, and the top of the housing 2 is provided with a sliding connection with the pull rod 13. Through holes, the upper end of the pull rod 13 is fixedly connected with a pull block 14, the lever arm of the pull rod 13 is provided with a spring two 15, and the two ends of the spring two 15 are respectively fixedly connected with the inner wall of the housing 2 and the surface of the support plate 5, through Pull up the pull block 14 and pass the pull rod 13 to drive the two support plates 5 to move upward, and when the pull block 14 is released, the elastic restoring force of the spring 2 15 can be used to move the two support plates 5 downward .

进一步的,为了减少取样时间,进而间接减轻了患者的疼痛,本发明中壳体2内设置有取样针16,并且取样针16位于两个夹持部之间,通过将活体组织1逐个串在取样针16上,从而可以在壳体2一次进入人体后,即可完成多次取样。Further, in order to reduce the sampling time and indirectly reduce the pain of the patient, a sampling needle 16 is arranged in the casing 2 of the present invention, and the sampling needle 16 is located between the two clamping parts, by stringing the living tissues 1 one by one On the sampling needle 16, so that multiple sampling can be completed after the casing 2 enters the human body once.

进一步的,为了使得活体组织1更容易被取样针16穿刺,本发明中取样针16的端部固定连接有转轴一17,转轴一17的端部转动连接在壳体2的内壁,壳体2的内壁固定连接有安装板18,安装板18的板壁转动连接有转轴二19,转轴一17的轴臂和转轴二19的轴臂均固定连接有锥形齿轮20,两个锥形齿轮20相啮合,转轴二19的轴臂还固定连接有齿轮21,任意一支撑板5的上表面固定连接有与齿轮21啮合的齿条板22,通过支撑板5上移,带动齿条板22上移,通过齿条板22上移并经齿条板22与齿轮21之间的啮合关系,带动齿轮21转动,通过齿轮21转动并经转轴二19和两个锥形齿轮20之间的啮合关系,带动转轴一17转动,通过转轴一17转动,带动取样针16转动,通过取样针16转动并配合活体组织1向取样针16方向移动,对活体组织1实现一个切削与钻进的过程,进而使得活体组织1更容易被取样针16穿刺。Further, in order to make the living tissue 1 more easily punctured by the sampling needle 16, the end of the sampling needle 16 in the present invention is fixedly connected with a rotating shaft 17, and the end of the rotating shaft 17 is rotatably connected to the inner wall of the housing 2, and the housing 2 The inner wall of the mounting plate 18 is fixedly connected with a mounting plate 18, and the wall of the mounting plate 18 is rotatably connected with a rotating shaft 2 19, and the shaft arm of the rotating shaft 17 and the shaft arm of the rotating shaft 2 19 are fixedly connected with a bevel gear 20, and the two bevel gears 20 are in phase meshing, the shaft arm of the rotating shaft 2 19 is also fixedly connected with a gear 21, and the upper surface of any one support plate 5 is fixedly connected with a rack plate 22 meshing with the gear 21, and when the support plate 5 moves upward, the rack plate 22 is moved upward , move up through the rack plate 22 and through the meshing relationship between the rack plate 22 and the gear 21, drive the gear 21 to rotate, rotate through the gear 21 and through the meshing relationship between the rotating shaft two 19 and the two bevel gears 20, Drive the rotating shaft 17 to rotate, through the rotating shaft 17, drive the sampling needle 16 to rotate, through the rotating of the sampling needle 16 and cooperate with the living tissue 1 to move towards the sampling needle 16, a cutting and drilling process is realized for the living tissue 1, and then make The living tissue 1 is more easily punctured by the sampling needle 16 .

进一步的,夹块7的下端开设有交错槽23,并且两个夹块7通过交错槽23可相互交叉,结合图8所示,使得两个夹块7运动至图6所示状态后,随着两个夹块7继续作相互靠拢的运动,即可通过交错槽23,使得两个夹块7相互交叉,达到了在不影响两个夹块7对活体组织1夹持效果的前提下,通过两个可相互交叉的夹块7,即可使得活体组织1被推动上移,并向取样针16方向移动。Further, the lower end of the clamping block 7 is provided with a staggered groove 23, and the two clamping blocks 7 can cross each other through the staggered groove 23, as shown in Figure 8, so that after the two clamping blocks 7 move to the state shown in Figure 6, then As the two clamping blocks 7 continue to move closer to each other, they can pass through the staggered groove 23, so that the two clamping blocks 7 intersect each other, reaching the premise of not affecting the clamping effect of the two clamping blocks 7 on the living tissue 1, The living tissue 1 can be pushed up and moved toward the sampling needle 16 through the two intersecting clamping blocks 7 .

请参阅图1至图9,本发明还提供一种病理科研究用活体组织检查器械的使用方法,包括以下步骤:Referring to Fig. 1 to Fig. 9, the present invention also provides a method for using a biopsy instrument for pathological research, comprising the following steps:

S1:在对活体组织1进行切割处理之后,活体组织1自掉落至患者体内的胃壁处,随后将壳体2伸入至患者的体内,并且在伸入后,固定块6的端部不与患者体内的胃壁相接触;S1: After the living tissue 1 is cut, the living tissue 1 falls to the stomach wall of the patient, and then the casing 2 is inserted into the patient's body, and after the insertion, the end of the fixing block 6 does not contact with the stomach wall in the patient;

S2:保持壳体2的位置,随后通过操纵驱动部,带动两个连板4上移,通过两个连板4上移,即可使得夹块7在跟随固定块6转动的同时,向患者体内胃壁方向移动,从而保证了夹块7的夹持路径可顺利的夹持到位于患者体内胃壁的活体组织1;S2: Keep the position of the housing 2, and then drive the two connecting plates 4 to move up by manipulating the driving part. By moving the two connecting plates 4 up, the clamping block 7 can move toward the patient while following the rotation of the fixed block 6. Move in the direction of the stomach wall in the body, thereby ensuring that the clamping path of the clamp block 7 can be smoothly clamped to the living tissue 1 located on the stomach wall in the patient's body;

S3:取样完成后,将壳体2移出人体,并且将活体组织1转移到光学显微镜下进行观察即可。S3: After the sampling is completed, the casing 2 is removed from the human body, and the living tissue 1 is transferred to an optical microscope for observation.

工作原理:该病理科研究用活体组织检查器械在使用时,首先在对活体组织1进行切割处理之后,活体组织1自掉落至患者体内的胃壁处,随后将壳体2伸入至患者的体内并如图1所示,此时固定块6远离拉块14的一端不与患者体内的胃壁相接触,继而减少了固定块6在转动时,对患者体内胃壁造成的摩损;Working principle: when the biopsy instrument for pathological research is used, firstly, after the living tissue 1 is cut and processed, the living tissue 1 falls to the stomach wall of the patient, and then the housing 2 is inserted into the patient's body. In the body and as shown in Figure 1, at this time, the end of the fixed block 6 away from the pull block 14 is not in contact with the stomach wall in the patient's body, thereby reducing the friction caused by the fixed block 6 to the stomach wall in the patient's body when it rotates;

然后保持壳体2的位置,并且通过上拉拉块14并经拉杆13,带动两个支撑板5上移,通过两个支撑板5上移,带动两个连板4上移,通过两个连板4上移并经连板4与转臂3之间的铰接关系,带动两个转臂3均以各自与壳体2之间的铰接点为圆心进行转动,通过两个转臂3转动,带动两个固定块6转动,通过两个固定块6远离拉块14的一端向相对方向转动,继而对活体组织1提供夹持力;Then keep the position of the housing 2, and by pulling up the pull block 14 and through the pull rod 13, drive the two support plates 5 to move up, move up through the two support plates 5, drive the two connecting plates 4 to move up, pass through the two The connecting plate 4 moves up and through the hinge relationship between the connecting plate 4 and the rotating arm 3, the two rotating arms 3 are driven to rotate with the hinge point between them and the housing 2 as the center of the circle, and the two rotating arms 3 rotate , to drive the two fixed blocks 6 to rotate, through which the ends of the two fixed blocks 6 away from the pull block 14 rotate in the opposite direction, and then provide clamping force to the living tissue 1;

上述过程中,通过两个支撑板5上移并经转臂3转动限制,带动两个连板4向相对方向移动,通过两个连板4向相对方向移动,使得绳一11拉动绕线轮10转动,通过绕线轮10转动,对绳二12进行放线并利用弹簧一9的弹性恢复力,使得夹块7在跟随固定块6转动的同时,向远离绕线轮10方向移动并至图5所示状态,此时即可对活体组织1进行夹持,本发明中夹块7在跟随固定块6转动的同时,可向患者体内胃壁方向移动,使得固定块6和夹块7均可在不对患者体内胃壁造成摩损的情况下,通过夹块7的移动,来保证夹块7的夹持路径可顺利的夹持到位于患者体内胃壁的活体组织1,从而相对现有技术中,通过类似剪刀状的活检钳取样时,为了保证位于患者体内胃壁的活体组织1可在活检钳两个夹头的夹持路径内,通常需要将活检钳的两个夹头抵接到患者体内胃壁,方可顺利进行取样,进而本发明减少了对患者体内胃壁造成的摩损;In the above process, the two supporting plates 5 are moved up and restricted by the rotation of the rotating arm 3, which drives the two connecting plates 4 to move in the opposite direction, and the two connecting plates 4 move in the opposite direction, so that the rope 11 pulls the reel 10 rotates, through the rotation of the winding wheel 10, the rope two 12 is released and the elastic restoring force of the spring one 9 is used, so that the clamp block 7 moves away from the winding wheel 10 while following the rotation of the fixed block 6 and reaches the In the state shown in Figure 5, the living tissue 1 can be clamped at this moment. In the present invention, the clamp block 7 can move toward the stomach wall in the patient's body while following the rotation of the fixed block 6, so that the fixed block 6 and the clamp block 7 are both Without causing friction to the stomach wall in the patient's body, the clamping block 7 can be moved to ensure that the clamping path of the clamping block 7 can be smoothly clamped to the living tissue 1 located on the stomach wall in the patient's body. , when sampling through scissor-like biopsy forceps, in order to ensure that the living tissue 1 located on the stomach wall of the patient can be within the clamping path of the two clamps of the biopsy forceps, it is usually necessary to abut the two clamps of the biopsy forceps into the patient's body The stomach wall can be sampled smoothly, and the invention reduces the friction caused to the stomach wall of the patient;

通过继续上拉拉块14,带动两个固定块6继续转动并经过图6所示状态,最终至图7所示状态,通过两个固定块6的转动,将被两个夹块7夹持的活体组织1推向取样针16处,并被取样针16穿刺固定,同时在活体组织1被取样针16穿刺的过程中,通过两个连板4向相对方向移动,对活体组织1的运动轨迹进行限制并进行挤压,继而相对于现有技术中,在直接推动活体组织1时,因活体组织1本身具备的柔软性,容易导致活体组织1的中心部难以被取样针16完整的穿刺,从而导致被取样针16穿刺后的活体组织1,活体组织1与取样针16之间的紧密性不佳,进而发生活体组织1自滑出取样针16的现象;By continuing to pull up the pull block 14, the two fixed blocks 6 are driven to continue to rotate and pass through the state shown in FIG. 6, and finally to the state shown in FIG. The living tissue 1 is pushed toward the sampling needle 16, and is punctured and fixed by the sampling needle 16. At the same time, when the living tissue 1 is punctured by the sampling needle 16, the two connecting plates 4 move in opposite directions, and the movement of the living tissue 1 The trajectory is limited and squeezed, and then compared with the prior art, when the living tissue 1 is directly pushed, due to the softness of the living tissue 1 itself, it is easy to cause the center of the living tissue 1 to be difficult to be completely punctured by the sampling needle 16 , resulting in the living tissue 1 pierced by the sampling needle 16, the tightness between the living tissue 1 and the sampling needle 16 is not good, and then the phenomenon that the living tissue 1 slips out of the sampling needle 16 occurs;

在运动至图7所示状态后,通过缓慢下移拉块14并利用弹簧二15的弹性恢复力,带动各个机构均反向运作并至图9所示状态,此时由于取样针16的针尖部已露出,继而便于取样针16的针尖部穿刺下一个活体组织1,同时通过再次拉动拉块14并重复上述运动,即可将活体组织1逐个串在取样针16上,从而可以在壳体2一次进入人体后,即可完成多次取样,减少取样时间,进而间接减轻了患者的疼痛;After moving to the state shown in Figure 7, by slowly moving down the pull block 14 and using the elastic restoring force of the second spring 15, each mechanism is driven to operate in reverse and to the state shown in Figure 9. part has been exposed, and then it is convenient for the needle tip of the sampling needle 16 to puncture the next living tissue 1. At the same time, by pulling the pull block 14 again and repeating the above-mentioned movement, the living tissue 1 can be strung on the sampling needle 16 one by one, so that it can be inserted into the housing. 2 After entering the human body once, multiple sampling can be completed, reducing the sampling time and indirectly reducing the pain of the patient;

多次取样完成后,将壳体2移出人体,并且将活体组织1转移到光学显微镜下进行观察。After multiple samplings are completed, the casing 2 is removed from the human body, and the living tissue 1 is transferred to an optical microscope for observation.

尽管已经示出和描述了本发明的实施例,对于本领域的普通技术人员而言,可以理解在不脱离本发明的原理和精神的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由所附权利要求及其等同物限定。Although the embodiments of the present invention have been shown and described, those skilled in the art can understand that various changes, modifications and substitutions can be made to these embodiments without departing from the principle and spirit of the present invention. and modifications, the scope of the invention is defined by the appended claims and their equivalents.

Claims (1)

1.一种病理科研究用活体组织检查器械,包括用于活体组织(1)检查的取样器,其特征在于:所述取样器包括壳体(2),所述壳体(2)的内壁设置有两个夹持部;1. A biopsy instrument for pathology research, comprising a sampler for biopsy (1) inspection, characterized in that: the sampler includes a housing (2), the inner wall of the housing (2) There are two clamping parts; 所述夹持部包括铰接在所述壳体(2)内壁的转臂(3),所述转臂(3)的端部铰接有连板(4),所述连板(4)的上端开设有通槽,所述连板(4)通过通槽滑动连接有支撑板(5),所述转臂(3)的表面固定连接有固定块(6),所述固定块(6)的下端开设有滑槽,所述固定块(6)通过所述滑槽滑动连接有夹块(7),还包括传动部,在所述夹块(7)跟随所述固定块(6)转动时,通过所述传动部的作用,带动所述夹块(7)沿所述滑槽的槽壁,作相对于所述固定块(6)伸出或伸入运动;The clamping part includes a rotating arm (3) hinged on the inner wall of the housing (2), the end of the rotating arm (3) is hinged with a connecting plate (4), and the upper end of the connecting plate (4) A through groove is opened, and the connecting plate (4) is slidably connected with a support plate (5) through the through groove, and the surface of the rotating arm (3) is fixedly connected with a fixed block (6), and the fixed block (6) The lower end is provided with a chute, and the fixed block (6) is slidably connected with the clamp block (7) through the chute, and also includes a transmission part, when the clamp block (7) follows the rotation of the fixed block (6) , through the action of the transmission part, the clamping block (7) is driven to move along the groove wall of the chute to extend or extend relative to the fixed block (6); 所述取样器还包括用于驱动所述支撑板(5)上下移动的驱动部;The sampler also includes a driving part for driving the support plate (5) to move up and down; 所述传动部包括穿设在所述固定块(6)内壁的限位杆(8),所述限位杆(8)的端部与所述夹块(7)的表面固定连接,所述限位杆(8)的杆臂套设有弹簧一(9),所述弹簧一(9)的两端部分别与所述固定块(6)的内壁和所述夹块(7)的表面固定连接,所述固定块(6)靠近其上端的内壁固定安装有绕线轮(10),所述绕线轮(10)的表面缠绕有绳一(11)和绳二(12),所述绳一(11)远离所述绕线轮(10)的一端与所述连板(4)靠近所述支撑板(5)的一端固定连接,所述绳二(12)远离所述绕线轮(10)的一端与所述夹块(7)的表面固定连接;The transmission part includes a limit rod (8) pierced on the inner wall of the fixed block (6), the end of the limit rod (8) is fixedly connected with the surface of the clamp block (7), and the The lever arm of the limit rod (8) is provided with a spring one (9), and the two ends of the spring one (9) are connected with the inner wall of the fixed block (6) and the surface of the clamp block (7) respectively. Fixedly connected, the inner wall of the fixed block (6) near its upper end is fixedly equipped with a winding wheel (10), and the surface of the winding wheel (10) is wound with rope one (11) and rope two (12), so The end of the rope one (11) away from the winding wheel (10) is fixedly connected to the end of the connecting plate (4) close to the support plate (5), and the rope two (12) is away from the winding One end of the wheel (10) is fixedly connected with the surface of the clamp block (7); 所述驱动部包括与所述支撑板(5)固定连接的拉杆(13),所述壳体(2)的顶部开设有与所述拉杆(13)滑动连接的通孔,所述拉杆(13)的上端固定连接有拉块(14),所述拉杆(13)的杆臂套设有弹簧二(15),所述弹簧二(15)的两端部分别与所述壳体(2)的内壁和所述支撑板(5)的表面固定连接;The driving part includes a pull rod (13) fixedly connected with the support plate (5), the top of the housing (2) is provided with a through hole slidingly connected with the pull rod (13), and the pull rod (13) ) is fixedly connected with a pull block (14), the lever arm of the pull rod (13) is provided with a spring two (15), and the two ends of the spring two (15) are respectively connected to the housing (2) The inner wall of the inner wall is fixedly connected with the surface of the support plate (5); 所述壳体(2)内设置有取样针(16),并且所述取样针(16)位于两个所述夹持部之间;A sampling needle (16) is arranged inside the housing (2), and the sampling needle (16) is located between the two clamping parts; 所述取样针(16)的端部固定连接有转轴一(17),所述转轴一(17)的端部转动连接在所述壳体(2)的内壁,所述壳体(2)的内壁固定连接有安装板(18),所述安装板(18)的板壁转动连接有转轴二(19),所述转轴一(17)的轴臂和所述转轴二(19)的轴臂均固定连接有锥形齿轮(20),两个所述锥形齿轮(20)相啮合,所述转轴二(19)的轴臂还固定连接有齿轮(21),任意一所述支撑板(5)的上表面固定连接有与所述齿轮(21)啮合的齿条板(22);The end of the sampling needle (16) is fixedly connected with a rotating shaft one (17), and the end of the rotating shaft one (17) is rotatably connected to the inner wall of the housing (2). The inner wall is fixedly connected with a mounting plate (18), and the wall of the mounting plate (18) is rotatably connected with a rotating shaft two (19), and the shaft arms of the rotating shaft one (17) and the shaft arms of the rotating shaft two (19) are both Bevel gear (20) is fixedly connected, and two described bevel gears (20) are meshed, and the axle arm of described rotating shaft two (19) is also fixedly connected with gear (21), and any one of described support plates (5 ) is fixedly connected with a rack plate (22) meshing with the gear (21); 所述夹块(7)的下端开设有交错槽(23),并且两个所述夹块(7)通过所述交错槽(23)可相互交叉。The lower end of the clamp block (7) is provided with a staggered groove (23), and two clamp blocks (7) can cross each other through the staggered groove (23).
CN202010583910.2A 2020-06-23 2020-06-23 Biopsy instrument for research of pathology department and use method thereof Active CN111631762B (en)

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US20130345596A1 (en) * 2012-06-25 2013-12-26 David S. Zimmon Apparatus and methods for removing and collecting biopsy specimens from biopsy devices with fixation and preparation for histopathological processing or other analysis
CN107219089B (en) * 2017-08-09 2023-04-21 湖南科技大学 A pendulum split box sampler and its sampling method
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