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CN111603626A - ECMO artificial membrane lung machine using dry heating gas - Google Patents

ECMO artificial membrane lung machine using dry heating gas Download PDF

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Publication number
CN111603626A
CN111603626A CN202010452665.1A CN202010452665A CN111603626A CN 111603626 A CN111603626 A CN 111603626A CN 202010452665 A CN202010452665 A CN 202010452665A CN 111603626 A CN111603626 A CN 111603626A
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Prior art keywords
membrane lung
oxygen
ecmo
lung machine
artificial membrane
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CN202010452665.1A
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袁毅强
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Chongqing Hongshan Medical Equipment Co ltd
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Chongqing Hongshan Medical Equipment Co ltd
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Priority to CN202010452665.1A priority Critical patent/CN111603626A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369Temperature treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The invention discloses an ECMO (electron cyclotron resonance) artificial membrane lung machine using dry heating gas, which comprises an ECMO artificial membrane lung machine body, wherein the ECMO artificial membrane lung machine body comprises a replaceable external oxygenation membrane lung and an oxygen drying device, and oxygen after being dried is input into the external oxygenation membrane lung by the oxygen drying device. This machine is through increasing oxygen drying device and oxygen heating device, carry out drying and heat treatment to the oxygen of inputing to external oxygenation membrane lung, generate with the moisture that reduces external oxygenation membrane lung, avoid too much moisture to grind the hair silk among the blood exchange structure, and then it is long when the use of single external oxygenation membrane lung is prolonged, and finally reach the effect that greatly reduces the usage cost of the artifical membrane lung machine of ECMO, avoid simultaneously because frequently changing external oxygenation membrane lung leads to patient's self blood loss, reduce medical risk.

Description

ECMO artificial membrane lung machine using dry heating gas
Technical Field
The invention relates to the technical field of medical science and technology equipment, in particular to an ECMO (electron cyclotron resonance) artificial membrane lung machine using dry heating gas.
Background
Extracorporeal membrane oxygenation (ECMO) is one of the important medical technologies commonly used to rescue the lives of critically ill patients at present, and aims to replace the functions of the heart and lung of a patient to ensure that the body of the patient has sufficient perfusion and oxygen supply. The ECMO plays a circulatory and respiratory support role in particular in the departments of cardiovascular surgery, cardiovascular medicine, respiratory medicine, emergency department, critical medical department, and the like. ECMO represents a clinical technique at the level of critical care in a hospital, a region, or even a country in a sense.
The ECMO technology is derived from the extracorporeal circulation technology of cardiac surgery, the Gibbon implements extracorporeal circulation in cardiac surgery for the first time in 1953 for over sixty years, the exploration road is long and tortuous, and with the continuous development of medical treatment, material, mechanical, electronic and other technologies, the support time of the ECMO is continuously prolonged at present, the curative effect of treating patients is continuously improved, so the ECMO technology is widely applied to clinical emergency treatment of critical illness.
ECMO is essentially an improved novel artificial membrane lung machine, which not only can play the role of artificial heart, but also can play the role of artificial lung. When the ECMO artificial membrane lung machine is used, blood can be led out from veins, oxygen is absorbed through the membrane lung, and carbon dioxide is discharged. The blood after gas exchange can return to the vein or artery under the action of a centrifugal pump or a peristaltic pump according to the clinical treatment requirement, and can respectively play roles of external respiration support and cardiac support. When the lung function or the cardiac function of a patient is seriously damaged, the ECMO can not only play the role of oxygenation of the lung, but also play the role of pumping blood of the heart, thereby striving for precious time for the treatment of the patient.
The ECMO artificial membrane lung machine system mainly comprises an extracorporeal oxygenation membrane lung, a centrifugal pump head and a pipeline. The ECMO pipeline can connect the extracorporeal oxygenation membrane lung with the centrifugal pump, is connected with an internal blood vessel through an arteriovenous cannula, and leads venous blood of a patient out of the body through the centrifugal pump. The general structure of the extracorporeal oxygenation membrane lung is shown in fig. 1, wherein venous blood is input from one end of the extracorporeal oxygenation membrane lung and output from the other end of the extracorporeal oxygenation membrane lung. The upper part of the extracorporeal oxygenation membrane lung, namely the blood exchange structure, is full of capillary filaments, and the lower part, namely the heating device, adopts a capillary heating device to heat blood. The blood exchanges with oxygen in the blood exchange structure, and then the exchanged blood enters the heating device to be heated and then is output to the human body.
The existing ECMO artificial membrane lung machine is very high in use price, the daily use cost reaches tens of thousands of RMB, and the specific reason is as follows: when the blood exchanges with oxygen in the blood exchange structure of the extracorporeal oxygenation membrane lung, the generated moisture can seep out from the permeation holes 4a on the outer wall of the capillary filaments. When the water is accumulated more, the water will gradually spread along the capillary and finally cause flooding of the capillary, and further block the permeation holes 4a of the outer wall of the capillary, and block the exchange of oxygen and CO 2. Generally, about 4h to 6h needs to replace an extracorporeal oxygenation membrane lung, which directly causes the use cost of ECMO to be high. Moreover, replacing the extracorporeal oxygenation membrane lung is also risky and is an inevitable medical risk. Replacement of a new extracorporeal oxygenation membrane lung can also result in blood loss to the patient.
Disclosure of Invention
The invention provides an ECMO (electron cyclotron resonance) artificial membrane lung machine using dry heating gas, which aims to solve the problems of capillary water seepage and blood heat preservation in the use process of the conventional ECMO artificial membrane lung machine, thereby solving the problem of higher ECMO use cost, avoiding the blood loss of a patient and reducing the medical risk.
The technical scheme of the invention is as follows: the utility model provides an use ECMO artificial membrane lung machine of dry heated gas, includes ECMO artificial membrane lung machine body, ECMO artificial membrane lung machine body includes removable external oxygenation membrane lung, its characterized in that: the device also comprises an oxygen drying device and an oxygen heating device, wherein the oxygen drying device inputs the dried oxygen into the extracorporeal oxygenation membrane lung.
Further: the oxygen drying device is drying equipment which adopts a physical drying mode to dry oxygen.
Further: the oxygen drying equipment is an adsorption dryer.
Further comprises an oxygen heating device, wherein the oxygen heating device heats the oxygen input to the extracorporeal oxygenation membrane lung.
Further, the oxygen heating device is an electric heating device which heats oxygen in an electric heating mode.
Has the advantages that: the scheme provides an ECMO artificial membrane lung machine using dry heating gas, which dries and heats oxygen input to an extracorporeal oxygenation membrane lung by adding an oxygen drying device and an oxygen heating device so as to reduce the generation of moisture in the extracorporeal oxygenation membrane lung; simultaneously, more moisture on the surface of the capillary can be taken away by dry hot air (oxygen after heating), the moisture in blood is prevented from seeping and gathering on the surface of the capillary, the use time of a single extracorporeal oxygenation membrane lung is prolonged, the use cost of the ECMO artificial membrane lung machine is finally greatly reduced, and the blood loss of a patient caused by frequent replacement of the extracorporeal oxygenation membrane lung is avoided, so that the medical risk is reduced. Meanwhile, the hot air also heats and preserves the heat of the blood in the capillary, so that a water heating and heat preservation device of the traditional artificial membrane lung machine and a blood exchange structure (consumable) of the artificial membrane lung are omitted, and the equipment and consumable cost is reduced. In addition, the extracorporeal blood volume of the blood which needs to be pumped for extracorporeal warming is also reduced, so that the ECMO device of the patent needs less extracorporeal circulation blood volume than the existing ECMO device.
Drawings
FIG. 1 is a first schematic diagram illustrating the operation of a conventional ECMO artificial membrane lung machine according to the present invention;
FIG. 2 is a schematic diagram of a second working principle of the conventional ECMO artificial membrane lung machine according to the present invention;
FIG. 3 is a schematic view showing the first working principle of an ECMO artificial membrane lung machine;
FIG. 4 is a schematic view of the working principle of the ECMO artificial membrane lung machine with the oxygen heating and drying device added according to the present invention;
fig. 5 is an enlarged view of the structure of the capillary filament according to the present invention.
Detailed Description
The invention is further illustrated by the following examples in conjunction with the accompanying drawings:
as shown in fig. 1, 2, 3, 4 and 2, the present invention discloses an ECMO artificial membrane lung machine using dry heated gas.
As shown in fig. 1 and 2, in operation, blood is drawn from a patient into an ECMO host and then delivered to capillary filaments 4 in a blood exchange structure 1 of an extracorporeal oxygenation membrane lung. Oxygen enters the cavity of the blood exchange structure 1 directly as shown by the arrows in fig. 1, and enters the filaments 4 through the outer wall permeation holes 4a of the filaments 4, completing the oxygen supply required for blood.
After oxygen is combined with hemoglobin in blood through the penetration holes 4a of the capillary 4, CO2 is released from the blood to the outside of the capillary 4, and water molecules slowly leak out through the penetration holes 4a of the capillary 4. Normally, after a new extracorporeal oxygenation membrane lung is used for 4h-6h, the water retained in the cavity of the blood exchange structure 1 and the water diffused on the surface of the capillary 4 are enough to cause the extracorporeal oxygenation membrane lung to be incapable of further working, because the water diffused on the surface of the capillary 4 can block part of the permeation holes 4a on the capillary 4, so that the oxygen and CO2 can not be further exchanged, and therefore, the extracorporeal oxygenation membrane lung needs to be replaced to promote the ECMO artificial membrane lung function to continue working.
For this reason, a technical path is conceivable that the water in the blood exchange structure 1 is reduced as much as possible to promote the effect of prolonging the service life of the extracorporeal oxygenation membrane lung, and at the same time, the moisture is taken away by external gas such as oxygen, so that the replacement frequency of the extracorporeal oxygenation membrane lung can be reduced, and the use cost of the ECMO artificial membrane lung machine can be reduced.
The technical path disclosed by the scheme is as follows: in the prior art, oxygen is prepared and then directly fed into the blood exchange structure 1. Thus, essentially oxygen already contains some amount of initial moisture when it is delivered to the extracorporeal oxygenation membrane lung. Water molecules in the blood in the capillary filaments 4 can slowly seep out through the permeation holes 4a of the capillary filaments 4, and the initial part of water continuously remains in the blood exchange structure 1, and simultaneously, the water from the permeation part in the blood of the patient is added, so that the total water amount in the blood exchange structure 1 is rapidly increased, and a new extracorporeal oxygenation membrane lung cannot be continuously used for about 4-6 hours and needs to be replaced.
Therefore, in the scheme, the technical means of drying the oxygen input into the extracorporeal oxygenation membrane lung is adopted, namely the oxygen drying device 2 is adopted to dry the oxygen input into the extracorporeal oxygenation membrane lung so as to prevent the oxygen from bringing external moisture into the extracorporeal oxygenation membrane lung and simultaneously take away water molecules by utilizing the dry oxygen. It should be noted that: the oxygen drying device 2 should be selected as a drying apparatus, such as an adsorption dryer or the like, which dries oxygen by preferentially adopting physical drying. This avoids the oxygen being contaminated with other impurities which are detrimental to the patient.
After the oxygen is dried, no external moisture enters the extracorporeal oxygenation membrane lung through the oxygen, meanwhile, the dry oxygen can absorb a large amount of moisture on the surface of the capillary, the hot air can accelerate the vaporization of the moisture on the surface of the capillary, and the membrane lung is discharged along with carbon dioxide gas, so that the service life of a single extracorporeal oxygenation membrane lung can be prolonged by times.
When the using time of a single external oxygenation membrane lung is prolonged, the external oxygenation membrane lung does not need to be continuously and frequently replaced when in use, so that the blood loss can be greatly reduced, and the harm to the body of a patient is reduced.
As shown in fig. 1, the conventional extracorporeal oxygenation membrane generally includes two parts, namely a blood exchange structure 1 and a capillary tube heating device 3, wherein blood is mixed with oxygen through the blood exchange structure 1, then heated through the capillary tube heating device 3, and then returned to the patient through other paths of the ECMO, so as to maintain the body temperature of the patient.
The blood exchange structure 1 and the capillary tube heating device 3 included in the conventional extracorporeal oxygenation membrane lung are generally integrated, and therefore need to be replaced together when replaced. Due to the implementation of the technical path of oxygen drying, in order to further reduce the cost of a single extracorporeal oxygenation membrane lung, the blood exchange structure 1 may be separated from the capillary tube heating device 3 in the future, that is, one extracorporeal oxygenation membrane lung only includes the blood exchange structure 1, and the capillary tube heating device 3 does not need to be added.
And aiming at the problem of heating blood, another technical path is adopted: the oxygen heating device 6, such as an electric heating device or an oxygen electric heater which adopts an electric heating mode to heat oxygen, is used for heating the oxygen input into the blood exchange structure 1 to heat the oxygen to 37-40 degrees, the blood can be heated to the temperature for maintaining the body temperature of a patient in the blood exchange structure 1, so that the blood does not need to be heated separately in the subsequent process, the structure of a capillary heating device can be omitted in the production, and the whole machine and the use cost of the ECMO artificial membrane lung machine are further reduced. Moreover, the heated oxygen can more quickly carry a large amount of water out of the blood exchange structure, thereby effectively preventing water from remaining in the blood exchange structure.
It should be noted that: the use of the ECMO artificial membrane lung machine under the modern medical condition is not widely popularized at present, but the ECMO artificial membrane lung machine has very strong functions and has a very great effect on severe patients. The ECMO is not available for people to buy, but the use cost is too high, so that the use cost is really too much for all hospitals, and the economic strength of many patients cannot meet the use requirement, so that the ECMO is not popularized and used in the whole country or the whole world.
The invention aims to improve the existing ECMO artificial membrane lung machine and improve the using method through the improvement, and aims to reduce the using frequency of the in-vitro oxygenation membrane lung, further greatly reduce the using cost of the ECMO artificial membrane lung machine, promote the using cost of the ECMO artificial membrane lung machine to be obviously reduced, finally realize that each patient can be used and can be used, and ensure that the ECMO artificial membrane lung machine can really benefit the whole mankind.
It should be noted that: the oxygen in this case is also referred to as air, and the heated oxygen is also referred to as hot air because the oxygen input to the extracorporeal oxygenation membrane is not 100% pure oxygen, so the oxygen and air are simply referred to as different but substantially the same, and the scope of protection in this case is not limited.
The above description is only exemplary of the present invention and should not be taken as limiting, and any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (5)

1. The utility model provides an use ECMO artificial membrane lung machine of dry heated gas, includes ECMO artificial membrane lung machine body, ECMO artificial membrane lung machine body includes removable external oxygenation membrane lung, its characterized in that: the device also comprises an oxygen drying device (2), and oxygen after drying is input into the extracorporeal oxygenation membrane lung by the oxygen drying device (2).
2. An ECMO artificial membrane lung machine using dry heated air as claimed in claim 1 wherein: the oxygen drying device (2) is drying equipment for drying oxygen in a physical drying mode.
3. An ECMO artificial membrane lung machine using dry heated air as claimed in claim 2 wherein: the oxygen drying equipment is an adsorption dryer.
4. The ECMO membrane lung machine using dry heating gas as set forth in claim 1, further comprising an oxygen heating device (6), wherein the oxygen heating device (6) heats the oxygen supplied to the extracorporeal oxygenation membrane lung.
5. An ECMO artificial membrane lung machine using dry heating gas according to claim 4, wherein the oxygen heating means (6) is an electric heating device for heating oxygen by electric heating.
CN202010452665.1A 2020-05-26 2020-05-26 ECMO artificial membrane lung machine using dry heating gas Pending CN111603626A (en)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013128375A1 (en) * 2012-03-01 2013-09-06 Eurosets S.R.L. Appliance connectable to a device for the extracorporeal oxygenation of blood
CN106178159A (en) * 2015-03-30 2016-12-07 Estor股份公司 Equipment and corresponding carbon dioxide for extracorporeal blood treatment are removed and oxygenate method
CN107073196A (en) * 2014-11-19 2017-08-18 马里兰大学,巴尔的摩 Artificial pulmonary system and its method used
WO2019246057A1 (en) * 2018-06-20 2019-12-26 The Regents Of The University Of Michigan Smart artificial lung and perfusion systems
CN111569174A (en) * 2020-05-26 2020-08-25 重庆弘善医疗设备有限公司 Application method of ECMO (electron cyclotron resonance) artificial membrane lung machine
CN212490966U (en) * 2020-05-26 2021-02-09 重庆弘善医疗设备有限公司 ECMO artificial membrane lung machine using dry heating gas

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013128375A1 (en) * 2012-03-01 2013-09-06 Eurosets S.R.L. Appliance connectable to a device for the extracorporeal oxygenation of blood
CN107073196A (en) * 2014-11-19 2017-08-18 马里兰大学,巴尔的摩 Artificial pulmonary system and its method used
CN106178159A (en) * 2015-03-30 2016-12-07 Estor股份公司 Equipment and corresponding carbon dioxide for extracorporeal blood treatment are removed and oxygenate method
WO2019246057A1 (en) * 2018-06-20 2019-12-26 The Regents Of The University Of Michigan Smart artificial lung and perfusion systems
CN111569174A (en) * 2020-05-26 2020-08-25 重庆弘善医疗设备有限公司 Application method of ECMO (electron cyclotron resonance) artificial membrane lung machine
CN212490966U (en) * 2020-05-26 2021-02-09 重庆弘善医疗设备有限公司 ECMO artificial membrane lung machine using dry heating gas

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