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CN111568450B - PET scanning data scattering correction method and device and computer equipment - Google Patents

PET scanning data scattering correction method and device and computer equipment Download PDF

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CN111568450B
CN111568450B CN202010430967.9A CN202010430967A CN111568450B CN 111568450 B CN111568450 B CN 111568450B CN 202010430967 A CN202010430967 A CN 202010430967A CN 111568450 B CN111568450 B CN 111568450B
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CN111568450A (en
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何鎏春
邓子林
赵勇
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Shanghai United Imaging Healthcare Co Ltd
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Abstract

The application relates to a PET scanning data scattering correction method, a device, a computer device and a readable storage medium, wherein the PET scanning data scattering correction method comprises the following steps: acquiring PET scan data of a scanned object over a first time (T1); determining a start time of scatter correction within a first time (T1) from the PET scan data volume; performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data; the corrected PET scan data is reconstructed over a second time (T2) resulting in a PET image. By changing the calculation structure of the PET scanning scattering correction, the scattering correction calculation is carried out in advance, the time required by PET reconstruction after the scanning is finished is shortened, the clinical PET scanning plotting time is further shortened, and the PET scanning efficiency is improved.

Description

PET scanning data scattering correction method and device and computer equipment
Technical Field
The application relates to the technical field of medical treatment, in particular to a PET scanning data scattering correction method, a PET scanning data scattering correction device and computer equipment.
Background
As the PET system is axially lengthened, the system sensitivity is also increased, resulting in better image quality and shorter scan time in clinical applications. Meanwhile, as the number of crystals of the PET system increases, the number of Line-of-response (LOR) lines in the PET system increases in a square relation of the number of crystals, so that the amount of calculation required for PET reconstruction also increases greatly.
In the conventional PET scanning process, the whole scanning process can be simplified as follows: the method comprises four parts of on-line scanning, data preliminary processing, scattering correction and image reconstruction, and further can divide the process into two parts of an on-line scanning process and an off-line processing process. The scanning and the preliminary processing of the data are completed synchronously in an online process, and the PET scattering correction and the image reconstruction are started to be carried out after the scanning is finished to obtain complete statistical data, referring to fig. 1. For a PET system, the method can cause the PET reconstruction speed to become slow, and further cause the problems that the imaging time in the clinical scanning is long and the efficiency of the clinical scanning is low.
Disclosure of Invention
The application provides a PET scanning data scattering correction method, a PET scanning data scattering correction device and computer equipment, and aims to at least solve the problems of long imaging time and low efficiency of clinical PET scanning in the related art.
In a first aspect, an embodiment of the present application provides a method for scatter correction of PET scan data, where the method includes:
acquiring PET scan data of a scanned object over a first time (T1);
determining a start time of scatter correction within the first time (T1) from a PET scan data volume;
performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data;
the corrected PET scan data is reconstructed over a second time (T2) resulting in a PET image.
In some of these embodiments, the second time (T2) has a time starting point that is no earlier than a time ending point of the first time (T1).
In some of these embodiments, after the step of determining a start time for scatter correction within the first time (T1), the method further comprises:
determining a scatter correction duration from the scanning system;
determining an end time of the scatter correction based on the start time and the duration.
In some of these embodiments, the method further comprises:
determining a time starting point of the second time (T2) from the end time.
In some of these embodiments, the expiration time is within the first time (T1).
In some of these embodiments, after scatter correcting the PET scan data for a first time (T1) to obtain corrected PET scan data, the method further comprises:
statistical scaling of the corrected PET scan data to match the complete data volume obtained at the completion of the scan.
In some of these embodiments, the statistically scaling the corrected PET scan data comprises:
performing statistical scaling processing on the corrected PET scanning data according to the quantity relation between the complete data and data used for scattering correction; or the like, or a combination thereof,
and performing least square fitting on the complete data according to the distribution of the corrected PET scanning data.
In a second aspect, the present application provides a PET scan data scatter correction apparatus, including:
an acquisition module for acquiring PET scan data of a scan object within a first time (T1);
a determination module for determining a start time of scatter correction within the first time (T1) depending on the PET scan data volume;
the correction module is used for performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data;
a reconstruction module for reconstructing the corrected PET scan data over a second time (T2) resulting in a PET image.
In a third aspect, an embodiment of the present application provides a computer device, which includes a memory, a processor, and a computer program stored on the memory and executable on the processor, and the processor executes the computer program to implement the PET scan data scatter correction method according to the first aspect.
In a fourth aspect, the present application provides a computer-readable storage medium, on which a computer program is stored, which when executed by a processor, implements the PET scan data scatter correction method as described in the first aspect above.
Compared with the related art, the PET scan data scatter correction method provided by the embodiment of the application comprises the steps of acquiring PET scan data of a scanned object within a first time (T1); determining a start time of scatter correction within the first time (T1) from a PET scan data volume; performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data; and reconstructing the corrected PET scanning data in a second time (T2) to obtain a PET image, so that the clinical PET scanning plotting time is shortened, and the PET scanning efficiency is improved.
The details of one or more embodiments of the application are set forth in the accompanying drawings and the description below to provide a more thorough understanding of the application.
Drawings
The accompanying drawings, which are included to provide a further understanding of the application and are incorporated in and constitute a part of this application, illustrate embodiment(s) of the application and together with the description serve to explain the application and not to limit the application. In the drawings:
FIG. 1 is a schematic diagram of a prior art PET scanning process provided in one embodiment;
FIG. 2 is a flow chart of a method for scatter correction of PET scan data according to an embodiment of the present application;
FIG. 3 is a schematic view of a PET scanning process provided in an embodiment of the present application;
FIG. 4 is a flowchart of determining a start time of a first time (T1) according to an embodiment of the present application;
FIG. 5 is a block diagram of a scatter correction apparatus for PET scan data according to an embodiment;
fig. 6 is a schematic hardware configuration diagram of a computer device according to an embodiment.
Detailed Description
In order to make the objects, technical solutions and advantages of the present application more clearly understood, the present application is described and illustrated below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application. All other embodiments obtained by a person of ordinary skill in the art based on the embodiments provided in the present application without any inventive step are within the scope of protection of the present application.
It is obvious that the drawings in the following description are only examples or embodiments of the present application, and that it is also possible for a person skilled in the art to apply the present application to other similar contexts on the basis of these drawings without inventive effort. Moreover, it should be appreciated that in the development of any such actual implementation, as in any engineering or design project, numerous implementation-specific decisions must be made to achieve the developers' specific goals, such as compliance with system-related and business-related constraints, which may vary from one implementation to another.
Reference in the specification to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the specification. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. Those of ordinary skill in the art will explicitly and implicitly appreciate that the embodiments described herein may be combined with other embodiments without conflict.
Unless defined otherwise, technical or scientific terms referred to herein shall have the ordinary meaning as understood by those of ordinary skill in the art to which this application belongs. Reference to "a," "an," "the," and similar words throughout this application are not to be construed as limiting in number, and may refer to the singular or the plural. The present application is directed to the use of the terms "including," "comprising," "having," and any variations thereof, which are intended to cover non-exclusive inclusions; for example, a process, method, system, article, or apparatus that comprises a list of steps or modules (elements) is not limited to the listed steps or elements, but may include other steps or elements not expressly listed or inherent to such process, method, article, or apparatus. Reference to "connected," "coupled," and the like in this application is not intended to be limited to physical or mechanical connections, but may include electrical connections, whether direct or indirect. The term "plurality" as referred to herein means two or more. "and/or" describes an association relationship of associated objects, meaning that three relationships may exist, for example, "A and/or B" may mean: a exists alone, A and B exist simultaneously, and B exists alone. The character "/" generally indicates that the former and latter associated objects are in an "or" relationship. Reference herein to the terms "first," "second," "third," and the like, are merely to distinguish similar objects and do not denote a particular ordering for the objects.
The various techniques described in this application may be applied to a PET scanning system, which may be a conventional short-axis PET scanning system, or a long-axis PET scanning system. The PET scanning system comprises a PET scanning device, a PET console computer device and a PET reconstruction computer device. Wherein the PET console computer device is used for sending control commands to the PET scanning device and the PET reconstruction computer device, displaying medical images and storing original scanning data. The PET scanning device is configured to receive a control command sent by the PET console computer device, acquire scanning data through a data acquisition module (which may specifically include a detector) in the PET scanning device, and transmit the scanning data to the reconstruction computer device. The reconstruction computer device is used for receiving the control command sent by the PET console computer device and receiving the scanning data sent by the PET scanning device, analyzing the scanning data, reconstructing an image, and transmitting the reconstructed image to the PET console computer device for display. Of course, the embodiments of the present application may also be applied to other scenarios, and are not limited herein. It should be noted that the above application scenarios are only shown for the convenience of understanding the present application, and the embodiments of the present application are not limited in any way in this respect. Rather, embodiments of the present application may be applied to any scenario where applicable.
Fig. 2 is a flowchart of a PET scan data scatter correction method according to an embodiment, and as shown in fig. 2, the PET scan data scatter correction method includes steps 210 to 240, where:
at step 210, PET scan data of a scanned object is acquired at a first time (T1).
The methods provided herein are directed to delayed scans, such as those of the tracer Fluorodeoxyglucose (FDG). At present, clinical human body scanning is mostly an applied delayed scanning method.
Delayed scanning, i.e., the time of scanning, is often spaced from the time of radiopharmaceutical injection by several tens of minutes to several hours, at which time the distribution of radioactivity in the body tends to equilibrate, which can be considered nearly constant within as few minutes of scanning. One of the main inputs required for the scatter correction algorithm is the radioactivity distribution in the measured object. Therefore, in the case of delayed scanning, it is not necessary to perform scatter correction after the scanning is completed, and it is quite possible to start scatter correction calculation before the end of the on-line scanning after certain data is collected, so that image reconstruction calculation can be performed directly at the start of off-line processing, and the calculation time of scatter correction is saved. Referring to fig. 3, the scattering correction process is started in the on-line scanning process, and the image reconstruction calculation is directly performed at the start of the off-line processing process, so that the reconstruction time is shortened, the plotting time is shortened, and the PET scanning efficiency is improved.
The scanning object in the present application may be a human body, an animal body, or some simulation experiment body, and the present embodiment is not limited.
Step 220, determining a starting time of the scatter correction within the first time (T1) according to the PET scanning data amount.
The scattering correction is performed on the premise that a certain scanning data volume is required, so that before the scattering correction, it is required to determine that the PET scanning data volume acquired by current scanning is a calculation volume meeting the scattering correction, and the scattering correction can be performed only when the acquired PET scanning data volume meets the preset data volume. The acquisition of the preset data volume PET scan data volume is calculated from the current scanning count rate (the number of randomly corrected coincidence events acquired in unit time), and in fact, the preset data volume PET scan data volume can be obtained in a short time after the scanning starts.
The preset data amount is related to the body type of the scanning object, and the larger the body type of the scanning object is, the larger the preset data amount is. The amount of data required for calculation of different body types of the scanning object can be obtained by evaluating the scattering correction result of a plurality of groups of scanning data. Specifically, the start time of the scatter correction can be directly determined by the amount of the calculation data required to determine whether the number of the coincidence events after the random correction currently acquired reaches the body type of the scanning object. And when the moment when the number of the collected coincidence events reaches the preset number is detected, the moment is used as the starting time of the scattering correction.
And step 230, performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data.
Step 240, reconstructing the corrected PET scan data over a second time (T2) to obtain a PET image.
The existing PET scatter correction method generally needs to wait for the end of scanning and the end of primary processing of raw data. For the conventional short-axis view PET scanning, no matter a Single Scattering Simulation (SSS) scattering correction algorithm or a Monte Carlo simulation scattering correction algorithm (MCS) is adopted, the scattering correction takes about several seconds to ten seconds, and the time consumption of scattering correction in the whole reconstruction process after the scanning is finished is not obvious. However, for the long axial PET system, taking the united image uEXPLORER as an example, the axial length is 8 times that of the conventional system, the number of LORs is 64 times that of the conventional PET system, and the Time of Flight (TOF) range to be considered is greatly increased along with the increase of the LOR inclination angle. In this case, the calculation amount required for the scatter correction by the single scatter simulation is about 64 times that of the conventional PET system in consideration of the number of LORs, and the calculation amount required for the monte carlo simulation is about 20 times that of the conventional PET system in consideration of the increase in the simulation space and the solid angle influence. No matter which algorithm is used, even if a multi-reconstruction-machine multi-node method is applied, the consumed time reaches the level of minutes, the occupied ratio is increased in the whole reconstruction process, and if special processing is not performed, the time required by clinical scanning mapping is obviously increased, and the PET scanning efficiency is reduced.
According to the PET scanning scattering correction method, the calculation structure of the PET scanning scattering correction is changed, the scattering correction process is started in the first time (T1), namely when certain PET scanning data volume is obtained in the scanning process, and the scattering correction calculation is carried out in advance. One of the main inputs required for the scatter correction algorithm is the radioactivity distribution in the measured object, which can be considered nearly constant in as few minutes as the distribution tends to equilibrate already at the start time of the first time (T1). Therefore, for the delayed scanning, the scattering correction of the PET scanning data during the scanning does not affect the PET scanning data, the time required for PET reconstruction after the scanning is finished can be shortened, the time required by the whole process of PET clinical scanning is further shortened, and the PET scanning efficiency is improved.
In one embodiment, the method further comprises determining a start time of the first time (T1) before the scanning process starts, including steps 410 to 430, wherein:
step 410, acquiring the medicine characteristics and the injection time of injecting the radioactive medicine to the scanning object;
step 420, determining the time length for the activity distribution of the radiopharmaceutical in the scanned object to reach a stable state according to the drug characteristics and the injection time;
step 430, determining a starting time of the first time (T1) according to the injection time and the duration.
Specifically, before the scanning process is started, whether the scanning process can be started is judged according to the property of the currently injected radiopharmaceutical and the injection time. For example, in the case of FDG drug scanning, when the injection time is too close to the scanning time, for example, only ten or more minutes, it is considered that the drug radioactivity distribution in the scanned object is still undergoing rapid changes, and the scanning procedure cannot be started. The scanning procedure is only started when the distribution of the activity of the drug in the scanned object is in equilibrium, so that the scatter correction calculation can be performed in the first time (T1). In the present embodiment, the time is counted from the injection time point, and the time point when the time length is reached is taken as the start time of the first time (T1). For example, if the injection time is 15 hours and 20 minutes, and the time period during which the radiopharmaceutical activity distribution reaches a steady state is 30 minutes, the start time of the first time (T1) is determined to be 15 hours and 50 minutes, so that the scanning time can be shortened to the maximum extent, and the scanning efficiency can be improved. Of course, it may be some time after 15 hours and 50 minutes.
In some of these embodiments, the second time (T2) has a time starting point that is no earlier than a time ending point of the first time (T1).
In this embodiment, after the online scanning is finished, that is, after the complete data volume of the PET scanning is obtained, the reconstruction of the PET scanning data is started. By reconstructing the PET scan data after the time end point of the first time (T1), a more comprehensive data may be utilized, and the reconstructed image quality may be improved. In some of these embodiments, after the determining a start time step for scatter correction within the first time (T1), the PET scan data scatter correction method further comprises:
determining a scatter correction duration from the scanning system;
determining an end time of the scatter correction based on the start time and the duration.
The above-mentioned scatter correction duration may be understood as a calculation time of the scatter correction, which is related to system parameters of the PET scanning system, for which the scatter correction duration is a known quantity, and may differ for different system parameters. When the scattering correction is performed, the duration of the scattering correction needs to be determined according to system parameters, and then the termination time of the scattering correction, that is, the time for completing the scattering correction is determined according to the starting time of the scattering correction.
In some of these embodiments, the PET scan data scatter correction method further comprises: determining a time starting point of the second time (T2) from the end time.
The time starting point of the second time (T2) may be at the end of the scatter correction or at any time after the end of the scatter correction.
In some of these embodiments, the expiration time is within the first time (T1).
Preferably, the termination time of the scattering correction coincides with the time termination point of the first time (T1), that is, the scattering correction can be completed just before the completion of the on-line scanning, so that the scattering correction calculation can be performed by using as much data as possible while the overall process speed is increased, and the scattering correction accuracy is improved. As an example, if the scanning time is T3, the duration of the scatter correction is T4, and the time for acquiring the predetermined data amount required for the scatter correction is T5, the start time T of the scatter correction should satisfy T ≧ T5 and T ≧ T3-T4 on the basis of being as early as possible.
It will be appreciated that since the scatter correction duration is determined by the PET scanning system, a reasonable scatter correction start time needs to be determined.
In some of these embodiments, there is a time interval between the time start of the second time (T2) and the time end of the first time (T1), the end time of the scatter correction being after the first time (T1).
It should be noted that, if the scanning object is a phantom, the radioactivity distribution in the phantom is considered to be unchanged, and the injection time does not need to be determined. The start time of the first time (T1) does not need to be determined, the phantom is scanned at any time, the PET scanning data can be subjected to scattering correction within the first time (T1), and the accuracy of a scattering correction result is not influenced.
The determination of the scan data amount and the start time of the scatter correction is performed to optimize the result of the earlier scatter correction, and a method such as forcibly performing scatter correction calculation using general data may be used.
The PET scanning scattering correction method is not limited to a long-axial PET system, and if the scattering correction time required by a common PET system is long, such as a Monte Carlo scattering correction algorithm or a double-scattering simulation algorithm, the method provided by the application can be used for optimizing a scanning structure and improving the PET scanning efficiency.
In some of these embodiments, after scatter correcting the PET scan data for a first time (T1) to obtain corrected PET scan data, the method further comprises:
statistical scaling of the corrected PET scan data to match the complete data volume obtained at the completion of the scan.
The scatter correction calculation results in a distribution of scatter events on the coincidence counting chord plot, i.e., a scatter correction chord plot. Since the scattering correction chord chart obtained by calculation in advance is the same as that used for the complete data obtained by the final scanning in shape distribution, the statistical data amount is different. Therefore, in specific use, in order to ensure the accuracy of the scattering correction as much as possible, the statistical scaling process needs to be performed on the obtained scattering correction chord chart after the scattering correction is completed so as to match the overall data statistics when the online scanning is finally completed. The statistical scaling here is not limited to direct scaling from actual statistics or fitting the final coincidence count chord with a scatter chord distribution.
In some of these embodiments, the statistically scaling the corrected PET scan data comprises: performing statistical scaling processing on the corrected PET scanning data according to the quantity relation between the complete data and data used for scattering correction; or, performing a least squares fit to the complete data based on the corrected distribution of PET scan data.
Specifically, the required scattering correction chord chart can be obtained by directly multiplying the total count of the scattering correction chord chart by an integral scaling coefficient according to the change of the total count of the scattering correction chord chart. Or, the shape distribution of the scattering correction chord graph obtained by calculation is utilized to carry out least square fitting on the whole data chord graph. The specific fitting method may be to fit the whole chord graph by combining with the true event, such as absolute scale algorithm, or to fit the scattering part chord graph by mask interception, such as calculation by tail fit algorithm.
It should be noted that the steps illustrated in the above-described flow diagrams or in the flow diagrams of the figures may be performed in a computer system, such as a set of computer-executable instructions, and that, although a logical order is illustrated in the flow diagrams, in some cases, the steps illustrated or described may be performed in an order different than here.
In one embodiment, as shown in fig. 5, there is provided a PET scan data scatter correction apparatus comprising: an acquisition module 510, a determination module 520, a correction module 530, and a reconstruction module 540, wherein:
an acquisition module 510 for acquiring PET scan data of a scan object over a first time (T1);
a determining module 520 for determining a start time of scatter correction within the first time (T1) based on the PET scan data volume;
a correction module 530, configured to perform scatter correction on the PET scan data from the start time to obtain corrected PET scan data;
a reconstruction module 540 configured to reconstruct the corrected PET scan data at a second time (T2) to obtain a PET image.
The PET scan data scatter correction apparatus provided in this embodiment acquires PET scan data of a scan object in a first time (T1) through the acquisition module 510; the determining module 520 determines a start time of scatter correction within the first time (T1) according to the PET scan data volume; the correction module 530 performs scattering correction on the PET scan data from the start time to obtain corrected PET scan data; a reconstruction module 540 reconstructs the corrected PET scan data over a second time (T2) resulting in a PET image. In the first time (T1), namely when a certain PET scanning data volume is acquired in the scanning process, the scattering correction process is started, and the scattering correction calculation is carried out in advance. The PET scanning data are subjected to scattering correction during scanning, influence cannot be caused, the time required for PET reconstruction after scanning is completed can be shortened, the clinical PET scanning plotting time is further shortened, and the PET scanning efficiency is improved.
In some of these embodiments, the second time (T2) has a time starting point that is no earlier than a time ending point of the first time (T1).
In some of these embodiments, the PET scan data scatter correction apparatus further comprises an end time determination module for determining a scatter correction duration from the scanning system; determining an end time of the scatter correction based on the start time and the duration.
In some of these embodiments, the PET scan data scatter correction apparatus further comprises a start point determining module for determining a temporal start point of the second time (T2) based on the end time.
In some of these embodiments, the expiration time is within the first time (T1).
In some embodiments, the PET scan data scatter correction apparatus further comprises a data processing module for performing statistical scaling on the corrected PET scan data to match the complete data volume obtained upon completion of the scan.
In some embodiments, the data processing module is further configured to perform statistical scaling on the corrected PET scan data according to a quantitative relationship between the complete data and data used for scatter correction; or the like, or a combination thereof,
performing a least squares fit of the corrected PET scan data according to the distribution of the corrected PET scan data.
For specific definition of the PET scan data scatter correction device, reference may be made to the above definition of the PET scan data scatter correction method, which is not described herein again. The modules in the PET scan data scatter correction apparatus can be wholly or partially implemented by software, hardware and a combination thereof. The modules can be embedded in a hardware form or independent from a processor in the computer device, and can also be stored in a memory in the computer device in a software form, so that the processor can call and execute operations corresponding to the modules.
In addition, the PET scan data scattering correction method described in conjunction with fig. 2 in the embodiment of the present application can be implemented by a computer device. Fig. 6 is a hardware structure diagram of a computer device according to an embodiment of the present application.
The computer device may comprise a processor 61 and a memory 62 in which computer program instructions are stored.
Specifically, the processor 61 may include a Central Processing Unit (CPU), or A Specific Integrated Circuit (ASIC), or may be configured to implement one or more Integrated circuits of the embodiments of the present Application.
Memory 62 may include, among other things, mass storage for data or instructions. By way of example, and not limitation, memory 62 may include a Hard Disk Drive (Hard Disk Drive, abbreviated HDD), a floppy Disk Drive, a Solid State Drive (SSD), flash memory, an optical Disk, a magneto-optical Disk, tape, or a Universal Serial Bus (USB) Drive or a combination of two or more of these. Memory 62 may include removable or non-removable (or fixed) media, where appropriate. The memory 62 may be internal or external to the data processing apparatus, where appropriate. In a particular embodiment, the memory 62 is a Non-Volatile (Non-Volatile) memory. In particular embodiments, memory 62 includes Read-Only Memory (ROM) and Random Access Memory (RAM). The ROM may be mask-programmed ROM, programmable ROM (PROM), erasable PROM (EPROM), electrically Erasable PROM (EEPROM), electrically rewritable ROM (EAROM), or FLASH Memory (FLASH), or a combination of two or more of these, where appropriate. The RAM may be a Static Random-Access Memory (SRAM) or a Dynamic Random-Access Memory (DRAM), where the DRAM may be a Fast Page Mode Dynamic Random-Access Memory (FPMDRAM), an Extended data output Dynamic Random-Access Memory (EDODRAM), a Synchronous Dynamic Random-Access Memory (SDRAM), and the like.
The memory 62 may be used to store or cache various data files for processing and/or communication use, as well as possibly computer program instructions for execution by the processor 62.
The processor 61 reads and executes computer program instructions stored in the memory 62 to implement any one of the PET scan data scatter correction methods in the above embodiments.
In some of these embodiments, the computer device may also include a communication interface 63 and a bus 60. As shown in fig. 6, the processor 61, the memory 62, and the communication interface 63 are connected via a bus 60 to complete mutual communication.
The communication interface 63 is used for implementing communication between various modules, apparatuses, units and/or devices in the embodiments of the present application. The communication port 63 may also be implemented with other components such as: the data communication is carried out among external equipment, image/data acquisition equipment, a database, external storage, an image/data processing workstation and the like.
Bus 60 includes hardware, software, or both coupling the components of the computer device to each other. Bus 60 includes, but is not limited to, at least one of the following: data Bus (Data Bus), address Bus (Address Bus), control Bus (Control Bus), expansion Bus (Expansion Bus), and Local Bus (Local Bus). By way of example and not limitation, bus 60 may include an Accelerated Graphics Port (AGP) or other Graphics Bus, an Enhanced Industry Standard Architecture (EISA) Bus, a Front-Side Bus (FSB), a Hyper Transport (HT) Interconnect, an ISA (ISA) Bus, an InfiniBand (InfiniBand) Interconnect, a Low Pin Count (LPC) Bus, a memory Bus, a microchannel Architecture (MCA) Bus, a PCI (Peripheral Component Interconnect) Bus, a PCI-Express (PCI-X) Bus, a Serial Advanced Technology Attachment (SATA) Bus, a vlslave Bus, a Video Bus, or a combination of two or more of these suitable electronic buses. Bus 60 may include one or more buses, where appropriate. Although specific buses are described and shown in the embodiments of the application, any suitable buses or interconnects are contemplated by the application.
The computer device may execute the PET scan data scatter correction method in the embodiment of the present application based on the acquired program instructions, thereby implementing the PET scan data scatter correction method described in conjunction with fig. 2.
In addition, in combination with the PET scan data scatter correction method in the foregoing embodiments, the embodiments of the present application may be implemented by providing a computer readable storage medium. The computer readable storage medium having stored thereon computer program instructions; the computer program instructions, when executed by a processor, implement any of the PET scan data scatter correction methods in the above embodiments.
The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.
The above-mentioned embodiments only express several embodiments of the present application, and the description thereof is more specific and detailed, but not construed as limiting the claims. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the concept of the present application, which falls within the scope of protection of the present application. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims (10)

1. A PET scan data scatter correction method, the method comprising:
acquiring PET scan data of a scan object within a first time T1;
determining a starting time of scatter correction within the first time T1 according to the PET scanning data amount;
performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data;
reconstructing the corrected PET scan data over a second time T2 to obtain a PET image.
2. The method according to claim 1, wherein the second time T2 has a time starting point not earlier than a time ending point of the first time T1.
3. The method of claim 1, wherein after the step of determining a start time for scatter correction within the first time T1, the method further comprises:
determining a scatter correction duration from the scanning system;
determining an end time of the scatter correction based on the start time and the duration.
4. The method of claim 3, further comprising:
and determining the time starting point of the second time T2 according to the ending time.
5. The method of claim 3, wherein the expiration time is within the first time T1.
6. The method of claim 1, wherein after scatter correcting the PET scan data for a first time T1 to obtain corrected PET scan data, the method further comprises:
statistical scaling of the corrected PET scan data to match the complete data volume obtained at the completion of the scan.
7. The method of claim 6, wherein said statistically scaling said corrected PET scan data comprises:
performing statistical scaling processing on the corrected PET scanning data according to the quantity relation between the complete data and data used for scattering correction; or the like, or, alternatively,
and performing least square fitting on the complete data according to the distribution of the corrected PET scanning data.
8. A PET scan data scatter correction apparatus, the apparatus comprising:
an acquisition module for acquiring PET scan data of a scan object within a first time T1;
a determining module, configured to determine a start time of scatter correction within the first time T1 according to the PET scan data amount;
the correction module is used for performing scattering correction on the PET scanning data from the starting time to obtain corrected PET scanning data;
and the reconstruction module is used for reconstructing the corrected PET scanning data within a second time T2 to obtain a PET image.
9. A computer device comprising a memory and a processor, the memory storing a computer program, wherein the processor implements the steps of the method of any one of claims 1 to 7 when executing the computer program.
10. A computer-readable storage medium, on which a computer program is stored, which, when being executed by a processor, carries out the steps of the method of any one of claims 1 to 7.
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