CN111408081A - Intelligent mask for detecting concentration of new coronavirus particles and detection method thereof - Google Patents
Intelligent mask for detecting concentration of new coronavirus particles and detection method thereof Download PDFInfo
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Abstract
The invention discloses an intelligent mask for detecting the concentration of new coronavirus particles and a detection method thereof, wherein the detection method of the intelligent mask for detecting the concentration of the new coronavirus particles comprises the following steps of S1: air enters the mask through a one-way breather valve on the outer layer of the mask; step S2: and a new coronavirus detection sensor which is communicated with the one-way breather valve and is also positioned on the outer layer of the mask detects the concentration of new coronavirus particles in the air entering the mask. The intelligent mask for detecting the concentration of the new coronavirus particles and the detection method thereof can detect the concentration of the new coronavirus particles, and send alarm information to a mobile phone of a user through a wireless module when the concentration of the new coronavirus particles in the air reaches a threshold value to remind the user of leaving.
Description
Technical Field
The invention belongs to the field of personal protection and the technical field of intelligent wearable equipment, and particularly relates to an intelligent mask for detecting the concentration of new coronavirus particles and a detection method of the intelligent mask for detecting the concentration of the new coronavirus particles.
Background
The GE Healthcare company of the health industry under the American general electric flag lists a plasma optical SPR (surface plasma resonance) detection technology as one of the best methods for rapid virus concentration detection, and compared with nucleic acid detection, the method has the advantages of being simple in one-step operation and fast, good and economical in the total flow time within 10 minutes. The SPR detection method is already applied to rapid, efficient and convenient detection of the concentrations of adenovirus, avian influenza and influenza A and B virus particles in laboratories. However, the conventional SPR optical detection equipment such as GE Biacore equipment and chips are expensive, so that the conventional SPR optical detection equipment cannot enter the virus infection detection application in clinical and household environments for a long time.
The publication number is: CN1056150498, entitled an intelligent protective mask, its technical solution discloses "comprising a mask body and a mask belt, wherein the mask body comprises a mask body sheet, an internal support part, a gas supplement ring, a battery, a sensor and a controller; the mask main body piece part comprises a filter body of a layered structure, and the filter body comprises an outer surface layer, a middle polymer composite membrane filter element and an inner surface layer; the inner supporting part is composed of a metal wire frame and an edge elastic part, the metal wire frame is used for constructing the shape of the mask, and the edge elastic part is attached to the face of a wearer; the gas supplementing ring links the wearer's breathing intensity by increasing the pressure of the gas flow through the filter; the battery is used for supplying power to the sensor and the controller; the sensor is used for recording wearing time of the mask, internal pressure of the mask and air flow strength of the edge of the internal supporting part and comprises a connecting module, a pressure sensing module and/or a touch force sensing module; the controller is used for controlling the attaching degree of the edge part elastic component of the inner supporting part and the face of the wearer and comprises an integrated circuit board, a connecting module and an execution module; the sensor and the controller are in wireless connection with the intelligent terminal through respective connection modules; when the pressure sensing module of the sensor detects that the airflow pressure at the edge part of the internal supporting part exceeds a set value, the controller adjusts the edge part elastic component to the face of the wearer, so that the combination pressure of the edge part elastic component and the face of the wearer is increased; the middle polymer composite membrane filter element is formed by mutually and closely superposing a sub-nanoscale porous polymer ultrathin layer and a porous carrier layer, wherein the aperture of the sub-nanoscale porous polymer ultrathin layer is 66-80 nm, the thickness of the sub-nanoscale porous polymer ultrathin layer is 0.05-0.08 mu m, the sub-nanoscale porous polymer ultrathin layer is made of polytetrafluoroethylene, polyvinylidene fluoride, acrylic acid copolymer, polyamide and polyethylene terephthalate, and the mass ratio of the five substances is (3.9-5): (1.1-1.6): 0.8-1.6): 0.5-1.1); the outer surface layer and the inner surface layer are made of porous non-woven fabrics, and the porous non-woven fabrics are two combinations of porous polyester non-woven fabrics and porous polysulfone non-woven fabrics; the connecting module of the sensor and the controller comprises one or more than two of a Bluetooth module, an infrared module and a Near Field Communication (NFC) module;
the intelligent terminal is an intelligent mobile phone or a tablet computer.
Taking the above patent as an example, the technical problem solved is that "if a common mask is worn, since the airflow circulation pressure at the protection part is higher, the gas flows in and out preferentially from the attachment part, and therefore the purpose of protecting against fine particles such as PM2.5, viruses or germs in the gas cannot be achieved, and the current masks cannot be designed with an attachment part for each user independently", so that no mask is designed specifically for detecting and protecting against new coronavirus, and an alarm function is provided. Therefore, the above problems are further improved.
Disclosure of Invention
The invention mainly aims to provide an intelligent mask for detecting the concentration of new coronavirus particles and a detection method thereof, which can detect the particle concentration of the new coronavirus particles and send alarm information to a mobile phone of a user through a wireless module when the concentration of the new coronavirus particles in the air reaches a threshold value to remind the user of leaving.
Another object of the present invention is to provide an intelligent mask for detecting the concentration of new coronavirus particles and a detection method thereof, wherein a molecule sensitive layer is disposed on an optical chip, and a specific binding substance for spike protein (S protein) on the surface of the new coronavirus is modified on the molecule sensitive layer, so that the new coronavirus particles can be easily adsorbed on the molecule sensitive layer.
Another object of the present invention is to provide an intelligent mask for detecting the particle concentration of new coronavirus and a detection method thereof, wherein the particle concentration of new coronavirus is detected by the linear change between the particle concentration of new coronavirus and a transmission signal of an optical chip.
In order to achieve the above object, the present invention provides a method for detecting a particle concentration of a new coronavirus (2019-nCoV)) in air, including the following steps:
step S1: air enters the mask through a one-way breather valve on the outer layer of the mask;
step S2: the new coronavirus detection sensor is communicated with the one-way breather valve and is also positioned on the outer layer of the mask to detect the concentration of new coronavirus particles in the air entering the mask;
step S3: when the concentration of new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor sends alarm information to the mobile phone through a wireless communication module (comprising a Bluetooth module);
step S4: the air that enters the inlet cowling inlayer loops through first nanofiber net (dual fail safe increases the effective interception to the particulate matter), opposite sex section fibre web (the surface has the slot, has increased the trapping capacity of filter media to the particulate matter), second nanofiber net (dual fail safe increases the effective interception to the particulate matter) and superfine fibre layer (ensure the absorption to extremely fine particulate matter) filter to nanofiber's advantage has:
(the multilayer filtering structure ensures the filtration of dust, oily particles, pollen, bacteria, virus colloid and other pollution sources in the air) (the diameter of mass-produced nano fibers is controlled within 100 nanometers, so that the performance of endowing the nano fiber filtering membrane with high efficiency and low resistance is realized, the filtering efficiency of more than 90% of 0.075 micron sodium chloride aerosol (GB2626) is maintained while the resistance within 90Pa is maintained, and the filtering efficiency of more than 95% of 0.3 micron oily particles (GB2626-2006) is realized (the oily particles can damage the electrostatic field of PP electret melt-blown cotton, so that the adsorption capacity of the PP melt-blown cotton on the oily particles is reduced));
(the PVD nanometer fiber film and PP electret melt-blown cotton are combined for use, the resistance can be kept within 120Pa, the filtering efficiency of more than 99 percent of 0.075 micron sodium chloride aerosol (GB2626) is kept, the filtering efficiency of more than 95 percent of 0.3 micron oily particles (GB2626) is realized, and the new national standard A type standard to be implemented is achieved)
(the ultra-strong combination of the nano-fiber and the carrier non-woven fabric can overcome the problem of low combination fastness of the nano-fiber and the common non-woven fabric at present, the damage of a nano-fiber layer caused by daily use can not be caused, and even the filtration performance can not be reduced after washing)
As a further preferable embodiment of the above technical means, step S2 is specifically implemented as the following steps:
step S2.1: a molecule sensitive layer is arranged on the surface (in the production stage) of an optical chip (a novel Nano plasma optical Nano SP sensor chip) arranged in the new coronavirus detection sensor; the optical chip is very sensitive to the deposition of surface sub-wavelength Nano particles, so that the concentration of the adsorbed virus particles can be rapidly, real-timely, in-situ, nondestructive and dynamically detected without marking (the optical chip does not need an optical coupling device for excitation and has higher surface area-volume ratio), and the quantitative analysis and determination of the surface adsorbed virus particles can be carried out by using the optical chip even only conventional photoelectricity High flux, wide linear concentration range and high stability. The number and concentration of the virus particles specifically bound on the surface of the optical chip are increased continuously along with the accumulation of time, and the light transmission signal of the optical chip is linearly changed, so that the light transmission signal is accurately measured by a photoelectric detection circuit)
Step S2.2: a specific binding substance aiming at the surface spike protein (S protein) of the new coronavirus is modified on the molecule sensitive layer;
step S2.3: the number and concentration of the new coronavirus particles specifically bound on the surface of the optical chip are increased along with time (the new coronavirus is easy to attach to the surface), so that the light transmission signal of the optical chip is changed linearly;
step S2.4: and the photoelectric detection circuit electrically connected with the optical chip detects the linear change of the light transmission signal of the optical chip and obtains the particle concentration of the new coronavirus in the air.
As a more preferable technical solution of the above technical solution, after step S2.4, the method further includes:
step S2.5: the optical chip corrects for non-specific binding, which is relatively weak on the surface. (the optical chip only generates obvious photoelectric signal change for surface specific binding reaction, and only generates very tiny baseline shift for non-specific binding reaction with relatively weak binding force so as to be corrected by the detection circuit.)
As a further preferable technical solution of the above technical solution, the new coronavirus detection sensor further includes L ED lamp and photosensitive element (PD), L ED lamp is located above the optical chip and has a distance of 8mm-10mm from the optical chip, the photosensitive element is located below the optical chip and is in contact with the optical chip, L ED lamp emits a stable light source which passes through the optical chip to irradiate the photosensitive element, and the photosensitive element detects intensity of the light source, when the new coronavirus is attached to the molecule sensitive layer of the optical chip, the intensity of the light source received by the photosensitive element changes linearly, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
In order to achieve the above object, the present invention further provides an intelligent mask for detecting particle concentration of a new coronavirus (2019-nCoV)) in air, including:
the mask comprises a mask outer layer, wherein the mask outer layer comprises a one-way breather valve and a new coronavirus detection sensor, the one-way breather valve and the new coronavirus detection sensor are symmetrically arranged on the mask outer layer, the new coronavirus detection sensor is detachably connected with one side of the mask outer layer, and the one-way breather valve is fixedly connected with the other side of the mask outer layer;
the gauze mask inlayer, the gauze mask inlayer includes first nanofiber net, heterosexual cross-section fibre web (there is the slot on the surface), second nanofiber net and superfine fibre layer, the gauze mask inlayer be equipped with the reservation mouth that one-way breather valve corresponds.
(the internal and external two-layer of gauze mask, the outer surface fabric of gauze mask is ventilative, high temperature resistant, resistant ultraviolet ray, can wash, can also use means such as ultraviolet ray ozone, hot water, steam to disinfect, advises every user to purchase 2 ~ 3 overcoat, washs the replacement and uses the inlayer for disposable N95 filter element, design working life about 10 hours, advises the user to change every day)
(the new coronavirus detection sensor can be detached, and can be sterilized by alcohol wiping or ultraviolet ray, and can be detached during cleaning or steam sterilization, and the mask can be fixed by a buckle or a snap fastener for clothing)
As a further preferable technical solution of the above technical solution, the new coronavirus detection sensor includes an optical chip (a new nanoplasmon optical Nano SPR sensor chip), L ED lamp, a photosensitive element (PD) and a wireless communication module (including a bluetooth module), the surface of the optical chip (in the production stage) is provided with a molecule sensitive layer, the molecule sensitive layer is modified with a specific binding substance for a surface spike protein (S protein) of the new coronavirus (so that the new coronavirus is easily attached thereto), L ED lamp is located above the optical chip and at a distance of 8mm to 10mm from the optical chip, the photosensitive element is located below the optical chip and in contact with the optical chip, the stable light source emitted by the L ED lamp passes through the optical chip to irradiate the photosensitive element and the photosensitive element detects the intensity of the light source, when the new coronavirus is attached to the molecule sensitive layer of the optical chip, the intensity of the light source received by the photosensitive element changes linearly, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
As a further preferable technical solution of the above technical solution, when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor sends alarm information to the mobile phone through the wireless communication module (including the bluetooth module).
Drawings
Fig. 1A is a schematic structural view of the mask outer layer of the intelligent mask for detecting the concentration of the new coronavirus particles according to the present invention.
Fig. 1B is a schematic structural view of the mask inner layer of the intelligent mask for detecting the concentration of the new coronavirus particles according to the present invention.
Fig. 2 is a schematic structural diagram of a new coronavirus detection sensor of the intelligent mask for detecting the concentration of new coronavirus particles according to the present invention.
The reference numerals comprise 10 parts of mask outer layer, 11 parts of one-way breather valve, 12 parts of new coronavirus detection sensor, 13 parts of optical chip, 14 parts of L ED lamp, 15 parts of photosensitive element, 20 parts of mask outer layer, 21 parts of reserved port.
Detailed Description
The following description is presented to disclose the invention so as to enable any person skilled in the art to practice the invention. The preferred embodiments in the following description are given by way of example only, and other obvious variations will occur to those skilled in the art. The basic principles of the invention, as defined in the following description, may be applied to other embodiments, variations, modifications, equivalents, and other technical solutions without departing from the spirit and scope of the invention.
Referring to fig. 1 of the drawings, fig. 1A is a schematic structural view of the mask outer layer of the intelligent mask for detecting the concentration of new coronavirus particles of the present invention, fig. 1B is a schematic structural view of the mask inner layer of the intelligent mask for detecting the concentration of new coronavirus particles of the present invention, and fig. 2 is a schematic structural view of a new coronavirus detection sensor of the intelligent mask for detecting the concentration of new coronavirus particles of the present invention.
In the preferred embodiment of the present invention, those skilled in the art should note that the wireless communication module, L ED lamp, etc. to which the present invention relates may be considered as prior art.
A first embodiment.
The invention discloses a detection method of an intelligent mask for detecting the concentration of new coronavirus particles, which is used for detecting the particle concentration of the new coronavirus (2019 novel coronavirus (2019-nCoV)) in the air, and comprises the following steps:
step S1: air enters the mask through the one-way breather valve 11 of the mask outer layer 10;
step S2: a new coronavirus detection sensor 12 which is communicated with the one-way breather valve 11 and is also positioned on the outer layer 10 of the mask detects the concentration of new coronavirus particles in the air entering the mask;
step S3: when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor 12 sends alarm information to the mobile phone through a wireless communication module (including a Bluetooth module);
step S4: the air that enters into inlet cover inlayer 20 loops through first nanofiber net (dual fail safe increases the effective interception to the particulate matter), opposite sex cross-section fibre web (there is the slot on the surface, has increased the capture capacity of filter media to the particulate matter), second nanofiber net (dual fail safe increases the effective interception to the particulate matter) and superfine fibre layer (ensure the absorption to extremely fine particulate matter) filter to nanofiber's advantage has:
(the multilayer filtering structure ensures the filtration of dust, oily particles, pollen, bacteria, virus colloid and other pollution sources in the air) (the diameter of mass-produced nano fibers is controlled within 100 nanometers, so that the performance of endowing the nano fiber filtering membrane with high efficiency and low resistance is realized, the filtering efficiency of more than 90% of 0.075 micron sodium chloride aerosol (GB2626) is maintained while the resistance within 90Pa is maintained, and the filtering efficiency of more than 95% of 0.3 micron oily particles (GB2626-2006) is realized (the oily particles can damage the electrostatic field of PP electret melt-blown cotton, so that the adsorption capacity of the PP melt-blown cotton on the oily particles is reduced));
(the PVD nanometer fiber film and PP electret melt-blown cotton are combined for use, the resistance can be kept within 120Pa, the filtering efficiency of more than 99 percent of 0.075 micron sodium chloride aerosol (GB2626) is kept, the filtering efficiency of more than 95 percent of 0.3 micron oily particles (GB2626) is realized, and the new national standard A type standard to be implemented is achieved)
(the ultra-strong combination of the nano-fiber and the carrier non-woven fabric can overcome the problem of low combination fastness of the nano-fiber and the common non-woven fabric at present, the damage of a nano-fiber layer caused by daily use can not be caused, and even the filtration performance can not be reduced after washing)
Specifically, step S2 is implemented as the following steps:
step S2.1: a molecule sensitive layer is arranged on the surface (in the production stage) of an optical chip 13 (a novel Nano plasma optical Nano SPR sensor chip) arranged in the new coronavirus detection sensor 12; the optical chip 13 is very sensitive to the deposition of the surface sub-wavelength Nano particles, so that the concentration of the adsorbed virus particles can be rapidly, real-timely, in-situ, nondestructive and dynamically detected without marking, and the detection system of the technology has simple structure, low cost and simple and convenient operation, so that the field real-time detection of the virus particles with the diameter of about 0.1 micron in spray and aerosol becomes possible (the optical chip 13 does not need to be matched and excited by an optical coupling device and has higher surface area-volume ratio, and the quantitative analysis and determination of the surface adsorbed virus particles can be carried out by using the optical chip 13 even only by conventional photoelectricity High flux, wide linear concentration range and high stability. The number and concentration of the virus particles specifically bound on the surface of the optical chip 13 will increase with time, and the transmission signal of the optical chip 13 will change linearly, so as to be accurately measured by the photoelectric detection circuit)
Step S2.2: the number and concentration of the new coronavirus particles specifically bound on the surface of the optical chip 13 are increased with time, so that the light transmission signal of the optical chip 13 is changed linearly;
step S2.3: the photoelectric detection circuit electrically connected with the optical chip 13 detects the linear change of the light transmission signal of the optical chip and obtains the particle concentration of the new coronavirus in the air.
Further, the new coronavirus detection sensor 12 further comprises L ED lamp 14 and photosensitive element 15(PD), L ED lamp is located above the optical chip 13 and is at a distance (preferably) of 8mm-10mm from the optical chip 13, photosensitive element 15 is located below the optical chip 13 and is in contact with (clinging to) the optical chip 13, a stable light source emitted by L ED lamp 14 passes through the optical chip 13 to irradiate the photosensitive element 15, and the photosensitive element 15 detects the intensity of the light source, when the new coronavirus is attached to the molecule sensitive layer of the optical chip 13, the intensity of the light source received by the photosensitive element changes linearly, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
The invention also discloses an intelligent mask for detecting the particle concentration of the new coronavirus (2019 novel coronavirus (2019-nCoV)) in the air, which comprises the following steps:
the mask outer layer 10, the mask outer layer 10 comprises a one-way breather valve 11 and a new coronavirus detection sensor 12, the one-way breather valve 11 and the new coronavirus detection sensor 12 are symmetrically arranged on the mask outer layer 10, the new coronavirus detection sensor 12 is detachably connected with one side of the mask outer layer 10, and the one-way breather valve 11 is fixedly connected with the other side of the mask outer layer 10;
(the internal and external two-layer of gauze mask, the outer 10 surface fabric of gauze mask is ventilative, high temperature resistant, resistant ultraviolet ray, can wash, can also use means such as ultraviolet ray ozone, hot water, steam to disinfect, advise every user to buy 2 ~ 3 overcoat, wash and replace and use the inner layer for disposable N95 filter element, design working life about 10 hours, advise the user to change every day)
(the new coronavirus detection sensor 12 can be detached, and can be sterilized by alcohol wiping or ultraviolet ray, and can be detached during cleaning or steam sterilization, and the mask can be fixed by a buckle or a snap fastener for clothing)
Preferably, the new coronavirus detection sensor 12 comprises an optical chip 13 (a new nanoplasmon optical NanoSPR sensor chip), L ED lamp 14, a photosensitive element 15(PD) and a wireless communication module (including a bluetooth module), wherein the surface of the optical chip 13 (at the production stage) is provided with a molecule sensitive layer, the molecule sensitive layer is modified with a specific binding substance for a surface spike protein (S protein) of the new coronavirus (so that the new coronavirus is easily attached thereto), the L ED lamp 14 is located above the optical chip 13 and at a distance (preferably) of 8mm to 10mm from the optical chip 13, the photosensitive element 15 is located below the optical chip 13 and is in contact (close contact) with the optical chip 13, a stable light source emitted by the L ED lamp 14 passes through the optical chip 13 to irradiate the photosensitive element 15, and the photosensitive element 15 detects the intensity of the light source, the intensity of the light source received by the photosensitive element changes linearly when the new coronavirus is attached to the molecule sensitive layer of the optical chip 13, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
Preferably, when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor 12 transmits an alarm message to the mobile phone through a wireless communication module (including a bluetooth module).
Preferred embodiments.
The invention discloses a detection method of an intelligent mask for detecting the concentration of new coronavirus particles, which is used for detecting the particle concentration of the new coronavirus (2019 novel coronavirus (2019-nCoV)) in the air, and comprises the following steps:
step S1: air enters the mask through the one-way breather valve 11 of the mask outer layer 10;
step S2: a new coronavirus detection sensor 12 which is communicated with the one-way breather valve 11 and is also positioned on the outer layer 10 of the mask detects the concentration of new coronavirus particles in the air entering the mask;
step S3: when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor 12 sends alarm information to the mobile phone through a wireless communication module (including a Bluetooth module);
step S4: the air that enters the inlet cowling inlayer loops through first nanofiber net (dual fail safe increases the effective interception to the particulate matter), opposite sex section fibre web (the surface has the slot, has increased the trapping capacity of filter media to the particulate matter), second nanofiber net (dual fail safe increases the effective interception to the particulate matter) and superfine fibre layer (ensure the absorption to extremely fine particulate matter) filter to nanofiber's advantage has:
(the multilayer filtering structure ensures the filtration of dust, oily particles, pollen, bacteria, virus colloid and other pollution sources in the air) (the diameter of mass-produced nano fibers is controlled within 100 nanometers, so that the performance of endowing the nano fiber filtering membrane with high efficiency and low resistance is realized, the filtering efficiency of more than 90% of 0.075 micron sodium chloride aerosol (GB2626) is maintained while the resistance within 90Pa is maintained, and the filtering efficiency of more than 95% of 0.3 micron oily particles (GB2626-2006) is realized (the oily particles can damage the electrostatic field of PP electret melt-blown cotton, so that the adsorption capacity of the PP melt-blown cotton on the oily particles is reduced));
(the PVD nanometer fiber film and PP electret melt-blown cotton are combined for use, the resistance can be kept within 120Pa, the filtering efficiency of more than 99 percent of 0.075 micron sodium chloride aerosol (GB2626) is kept, the filtering efficiency of more than 95 percent of 0.3 micron oily particles (GB2626) is realized, and the new national standard A type standard to be implemented is achieved)
(the ultra-strong combination of the nano-fiber and the carrier non-woven fabric can overcome the problem of low combination fastness of the nano-fiber and the common non-woven fabric at present, the damage of a nano-fiber layer caused by daily use can not be caused, and even the filtration performance can not be reduced after washing)
Specifically, step S2 is implemented as the following steps:
step S2.1: a molecule sensitive layer is arranged on the surface (in the production stage) of an optical chip 13 (a novel Nano plasma optical Nano SPR sensor chip) arranged in the new coronavirus detection sensor 12; the optical chip 13 is very sensitive to the deposition of the surface sub-wavelength Nano particles, so that the concentration of the adsorbed virus particles can be rapidly, real-timely, in-situ, nondestructive and dynamically detected without marking, and the detection system of the technology has simple structure, low cost and simple and convenient operation, so that the field real-time detection of the virus particles with the diameter of about 0.1 micron in spray and aerosol becomes possible (the optical chip 13 does not need to be matched and excited by an optical coupling device and has higher surface area-volume ratio, and the quantitative analysis and determination of the surface adsorbed virus particles can be carried out by using the optical chip 13 even only by conventional photoelectricity High flux, wide linear concentration range and high stability. The number and concentration of the virus particles specifically bound on the surface of the optical chip 13 will increase with time, and the transmission signal of the optical chip 13 will change linearly, so as to be accurately measured by the photoelectric detection circuit)
Step S2.2: a specific binding substance aiming at the surface spike protein (S protein) of the new coronavirus is modified on the molecule sensitive layer;
step S2.3: the number and concentration of the new coronavirus particles specifically bound on the surface of the optical chip 13 are increased with time (the new coronavirus is easy to attach to the surface), so that the light transmission signal of the optical chip is changed linearly;
step S2.4: the photoelectric detection circuit electrically connected with the optical chip 13 detects the linear change of the light transmission signal of the optical chip and obtains the particle concentration of the new coronavirus in the air.
More specifically, after step S2.4, the method further comprises:
step S2.5: the optical chip 13 corrects for non-specific binding, which is relatively weak in binding force on the surface. (the optical chip 13 generates only an obvious photoelectric signal change for the surface-specific binding reaction, and generates only a very slight baseline shift for the non-specific binding reaction with a relatively weak binding force to be corrected by the detection circuit.)
Further, the new coronavirus detection sensor 12 further comprises L ED lamp 14 and photosensitive element 15(PD), L ED lamp is located above the optical chip 13 and is at a distance (preferably) of 8mm-10mm from the optical chip 13, photosensitive element 15 is located below the optical chip 13 and is in contact with (clinging to) the optical chip 13, a stable light source emitted by L ED lamp 14 passes through the optical chip 13 to irradiate the photosensitive element 15, and the photosensitive element 15 detects the intensity of the light source, when the new coronavirus is attached to the molecule sensitive layer of the optical chip 13, the intensity of the light source received by the photosensitive element changes linearly, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
The invention also discloses an intelligent mask for detecting the particle concentration of the new coronavirus (2019 novel coronavirus (2019-nCoV)) in the air, which comprises the following steps:
the mask outer layer 10, the mask outer layer 10 comprises a one-way breather valve 11 and a new coronavirus detection sensor 12, the one-way breather valve 11 and the new coronavirus detection sensor 12 are symmetrically arranged on the mask outer layer 10, the new coronavirus detection sensor 12 is detachably connected with one side of the mask outer layer 10, and the one-way breather valve 11 is fixedly connected with the other side of the mask outer layer 10;
(the internal and external two-layer of gauze mask, the outer 10 surface fabric of gauze mask is ventilative, high temperature resistant, resistant ultraviolet ray, can wash, can also use means such as ultraviolet ray ozone, hot water, steam to disinfect, advise every user to buy 2 ~ 3 overcoat, wash and replace and use the inner layer for disposable N95 filter element, design working life about 10 hours, advise the user to change every day)
(the new coronavirus detection sensor 12 can be detached, and can be sterilized by alcohol wiping or ultraviolet ray, and can be detached during cleaning or steam sterilization, and the mask can be fixed by a buckle or a snap fastener for clothing)
Preferably, the new coronavirus detection sensor 12 comprises an optical chip 13 (a new nanoplasmon optical NanoSPR sensor chip), L ED lamp 14, a photosensitive element 15(PD) and a wireless communication module (including a bluetooth module), wherein the surface of the optical chip 13 (at the production stage) is provided with a molecule sensitive layer, the molecule sensitive layer is modified with a specific binding substance for a surface spike protein (S protein) of the new coronavirus (so that the new coronavirus is easily attached thereto), the L ED lamp 14 is located above the optical chip 13 and at a distance (preferably) of 8mm to 10mm from the optical chip 13, the photosensitive element 15 is located below the optical chip 13 and is in contact (close contact) with the optical chip 13, a stable light source emitted by the L ED lamp 14 passes through the optical chip 13 to irradiate the photosensitive element 15, and the photosensitive element 15 detects the intensity of the light source, the intensity of the light source received by the photosensitive element changes linearly when the new coronavirus is attached to the molecule sensitive layer of the optical chip 13, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
Preferably, when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor 12 transmits an alarm message to the mobile phone through a wireless communication module (including a bluetooth module).
Preferably, the light source emits light, the light passes through the SPR nano optical material (optical chip) and is sensed by the PD photosensitive element, then the surface of the SPR nano optical material (optical chip) is modified aiming at the spinous process (S) protein on the new coronavirus, the SPR nano optical material is particularly easy to react with the new coronavirus, the new coronavirus is particularly easy to adsorb on the surface of the material, then the concentration of virus particles adsorbed on the surface can be sensed by the PD photosensitive element and presents a certain linear relation, and thus a quantitative basis is provided for measurement.
It should be noted that the technical features of the wireless communication module, L ED lamp, etc. related to the present patent application should be regarded as the prior art, and the specific structure, operation principle, and control manner and spatial arrangement manner that may be related to these technical features are conventional in the art, and should not be regarded as the point of the present patent, and the present patent is not further specifically described in detail.
It will be apparent to those skilled in the art that modifications and equivalents may be made in the embodiments and/or portions thereof without departing from the spirit and scope of the present invention.
Claims (7)
1. A detection method of an intelligent mask for detecting the concentration of new coronavirus particles is used for detecting the particle concentration of the new coronavirus particles in the air, and is characterized by comprising the following steps:
step S1: air enters the mask through a one-way breather valve on the outer layer of the mask;
step S2: the new coronavirus detection sensor is communicated with the one-way breather valve and is also positioned on the outer layer of the mask to detect the concentration of new coronavirus particles in the air entering the mask;
step S3: when the concentration of the new coronavirus particles in the air entering the inlet cover reaches a threshold value, the new coronavirus detection sensor sends alarm information to the mobile phone through the wireless communication module;
step S4: and air entering the inner layer of the inlet cover is filtered sequentially through the first nanofiber net, the fiber net with the different cross section, the second nanofiber net and the superfine fiber layer.
2. The method for detecting the concentration of the novel coronavirus particles in the intelligent mask as claimed in claim 1, wherein the step S2 is implemented as the following steps:
step S2.1: a molecule sensitive layer is arranged on the surface of the optical chip arranged in the new coronavirus detection sensor;
step S2.2: a specific binding substance aiming at the surface spike protein of the new coronavirus is modified on the molecule sensitive layer;
step S2.3: the number and concentration of the new coronavirus particles specifically bound on the surface of the optical chip are continuously increased with time, so that a light transmission signal of the optical chip is linearly changed;
step S2.4: and the photoelectric detection circuit electrically connected with the optical chip detects the linear change of the light transmission signal of the optical chip and obtains the particle concentration of the new coronavirus in the air.
3. The method for detecting the concentration of the new coronavirus particles in the intelligent mask as claimed in claim 2, further comprising the following steps after step S2.4:
step S2.5: the optical chip corrects for non-specific binding, which is relatively weak on the surface.
4. The method as claimed in claim 3, wherein the new coronavirus particle concentration detection sensor further comprises L ED lamp and photosensitive element, L ED lamp is located above the optical chip and at a distance of 8mm-10mm from the optical chip, the photosensitive element is located below the optical chip and in contact with the optical chip, L ED lamp emits stable light source to irradiate the photosensitive element through the optical chip and the photosensitive element detects intensity of the light source, when the new coronavirus is attached to the molecule sensitive layer of the optical chip, the intensity of the light source received by the photosensitive element changes linearly, and the particle concentration of the new coronavirus is obtained according to the linear change of the intensity of the light source.
5. The utility model provides a new coronavirus particle concentration detection intelligence gauze mask for detect the particle concentration of new coronavirus in the air, its characterized in that includes:
the mask comprises a mask outer layer, wherein the mask outer layer comprises a one-way breather valve and a new coronavirus detection sensor, the one-way breather valve and the new coronavirus detection sensor are symmetrically arranged on the mask outer layer, the new coronavirus detection sensor is detachably connected with one side of the mask outer layer, and the one-way breather valve is fixedly connected with the other side of the mask outer layer;
the gauze mask inlayer, the gauze mask inlayer includes first nanofiber net, heterosexual cross-section fibre web, second nanofiber net and superfine fibre layer, the gauze mask inlayer be equipped with the reservation mouth that one-way breather valve corresponds.
6. The intelligent mask according to claim 5, wherein the new coronavirus particle concentration detection sensor comprises an optical chip, L ED lamp, a photosensitive element and a wireless communication module, the surface of the optical chip is provided with a molecule sensitive layer, the molecule sensitive layer is modified by a specific binding substance aiming at the spike protein on the surface of the new coronavirus, L ED lamp is positioned above the optical chip and has a distance of 8mm-10mm from the optical chip, the photosensitive element is positioned below the optical chip and is in contact with the optical chip, a stable light source emitted by the L ED lamp passes through the optical chip and irradiates the photosensitive element, the photosensitive element detects the intensity of the light source, the intensity of the light source received by the photosensitive element changes linearly when the new coronavirus is attached to the molecule sensitive layer of the optical chip, and the particle concentration of the new coronavirus particle is obtained according to the linear change of the intensity of the light source.
7. The intelligent mask for detecting the concentration of the new coronavirus particles according to claim 6, wherein when the concentration of the new coronavirus particles in the air entering the mask reaches a threshold value, the new coronavirus detection sensor sends alarm information to a mobile phone through a wireless communication module.
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