CN111381059A - Sample analyzer - Google Patents

Abstract

The application discloses a sample analyzer. The sample analyzer comprises a shell, a blood cell detection assembly, an immunodetection assembly, a sampling assembly, a reagent refrigeration assembly and a detection assembly, wherein a first space, a second space, a third space and a fourth space are formed on the shell; the sampling assembly comprises a mounting plate and a sampling needle, and the sampling needle is used for sucking or releasing sample liquid to the blood cell detection assembly and the immunity detection assembly; the reagent refrigerating assembly is arranged in the third space and is used for refrigerating reagents; the detection assembly is arranged in the second space and is used for detecting detection liquid formed in the blood cell detection assembly. Through four spaces of casing partition to correspondingly install the part in each space, the sample analysis appearance structural configuration that this application provided is rationally distributed, and each part is arranged tightly, can reduce sample analysis appearance's volume relatively.

Description

Sample analyzer

Technical Field

The application relates to the technical field of medical equipment, in particular to a sample analyzer.

Background

A sample analyzer is an apparatus for analyzing data of a biological sample such as blood or urine.

Blood, urine and the like are generally analyzed by means of reagents, and then components such as containers for containing the reagents and reaction tanks for reaction are gathered in the sample analyzer, and at present, the functional requirements for the sample analyzer are more and more, the sample analyzer is provided with more functional components, if the sample analyzer does not have a good spatial structure layout, the sample analyzer is bulked, and then the flow paths of sample liquid, the reagents and the like in the sample analyzer are relatively increased, so that the detection speed is reduced, and meanwhile, the sample analyzer is required to relatively consume more energy.

Disclosure of Invention

The application provides a sample analyzer to solve sample analyzer structural layout unreasonable problem.

In order to solve the technical problem, the application adopts a technical scheme that: a sample analyzer is provided. The sample analyzer comprises a shell, a blood cell detection assembly, an immunodetection assembly, a sampling assembly, a reagent refrigeration assembly and a detection assembly, wherein a first space, a second space, a third space and a fourth space are formed on the shell; the sampling assembly comprises a mounting plate and a sampling needle, and the sampling needle is used for sucking or releasing sample liquid to the blood cell detection assembly and the immunity detection assembly; the reagent refrigerating assembly is arranged in the third space and is used for refrigerating reagents; the detection assembly is arranged in the second space and is used for detecting detection liquid formed in the blood cell detection assembly.

In a specific embodiment, the sample analyzer further includes an injector assembly, the injector assembly is connected to a side of the front side plate departing from the rear side plate, the injector assembly is respectively communicated with the sampling needle, the blood cell detection assembly, the immunity detection assembly and the detection assembly through pipelines, and is used for providing power for the sampling needle to suck or release the sample liquid, adding diluent into the blood cell detection assembly and the immunity detection assembly and injecting the diluent into the detection assembly to form sheath liquid with the detection liquid for detection by the detection assembly.

In a specific embodiment, the sample analyzer still includes the autoinjection subassembly, the autoinjection subassembly set up in the preceding curb plate deviates from one side of posterior lateral plate, the autoinjection subassembly is used for sending the sample cup to the appearance position of inhaling, so that the sampling needle sampling.

In a specific embodiment, be equipped with the installation roof beam on the casing, the bottom side of autoinjection subassembly is equipped with the slide that the deflector encloses and establishes, and corresponds the one end of slide is equipped with the baffle, the slide is used for corresponding the cover to establish the installation roof beam, the baffle be used for with the one end of installation roof beam is connected.

In a specific embodiment, the sample analyzer further includes a first quantitative pump assembly, the first quantitative pump assembly is disposed in the third space and located between the reagent refrigeration assembly and the rear side plate, and one end of the first quantitative pump assembly is communicated with the reagent refrigeration assembly through a pipeline, and the other end of the first quantitative pump assembly is communicated with the blood cell detection assembly and/or the immunoassay detection assembly, so as to quantitatively add the reagent stored in the reagent refrigeration assembly into the blood cell detection assembly and/or the immunoassay detection assembly.

In a specific embodiment, be equipped with reagent detection opto-coupler on the posterior lateral plate, just reagent detection opto-coupler is located on the pipeline between the cold-stored subassembly of reagent and the first quantitative pump package spare for detect whether have reagent in the pipeline, and then judge whether need change in the cold-stored subassembly of reagent the reagent.

In a specific embodiment, the sample analyzer further includes a reagent storage assembly disposed on a side of the front side plate away from the rear side plate, a second quantitative pump assembly is further disposed in the third space, the second quantitative pump assembly is located between the reagent refrigeration assembly and the front side plate, and the second quantitative pump is configured to quantitatively add a reagent stored in the reagent storage assembly to the blood cell detection assembly and/or the immunoassay assembly.

In a specific embodiment, a first air valve set is disposed on a side of the second partition plate away from the fourth space, and the first air valve set is connected with the first dosing pump assembly and the second dosing pump assembly and used for controlling the first dosing pump assembly and the second dosing pump assembly to take materials.

In a specific embodiment, the sample analyzer further includes a waste liquid treatment tank, the waste liquid treatment tank is disposed on the rear side plate and located in the first space, the blood cell detection assembly and the immunoassay detection assembly are both communicated with the waste liquid treatment tank through pipelines, and pressure-breaking valves are further connected to the pipelines between the blood cell detection assembly, the immunoassay detection assembly and the waste liquid treatment tank and used for controlling whether waste liquid enters the waste liquid treatment tank or not.

In a specific embodiment, the sample analyzer further includes a second air valve set and a right side plate, the right side plate is hinged to the rear side plate, and the second air valve set is disposed on the right side plate and is communicated with the press-breaking valve.

In a specific embodiment, the sample analyzer further includes an air pump assembly and an air source processing assembly, the air pump assembly is located in the second space, the air source processing assembly is disposed on the right side plate, the air pump assembly is connected to the air source processing assembly through a pipeline, and the air source processing assembly is connected to the first air valve set and the second air valve set.

In a specific embodiment, the blood cell detection subassembly with the immunodetection subassembly is followed the mounting panel moves towards arranging in proper order and sets up, wherein the blood cell detection subassembly includes follows the mounting panel moves towards blood cell reaction cell and the blood cell detection pond of arranging in proper order, the blood cell reaction pond is used for providing blood cell and realizes five categorised reaction sites and the detection liquid that forms can be provided detection subassembly, the blood cell detection pond is arranged in realizing three classifications and counting with blood cell in the blood, the immunodetection subassembly is arranged in realizing that multichannel specific protein detects in the blood.

In a specific embodiment, one side of the first partition board departing from the second space is provided with a first liquid valve group, one side of the rear side board facing the front side board is provided with a second liquid valve group, the first liquid valve group is used for controlling corresponding blood cell detection reagents to enter the blood cell reaction tank, and the second liquid valve group is used for controlling corresponding blood cell detection reagents to enter the blood cell detection tank.

In a specific embodiment, a circuit board assembly is installed in the fourth space, the circuit board assembly includes a control board and a drive board, the drive board is connected to the third partition board, the control board is hinged to the top side of the first partition board through a connecting assembly, and a support column is supported between the connecting assembly and the third partition board, so that the connecting assembly can cover the drive board.

The beneficial effect of this application is: in contrast to the state of the art, the present application discloses a sample analyzer. Through separating into four spaces with the casing, and with blood cell detection subassembly, immunodetection subassembly and sampling subassembly set up in first space, set up detection subassembly in the second space, set up the cold-stored subassembly of reagent in the third space, wherein second space and third space all are adjacent with first space, make the cold-stored subassembly of reagent, detection subassembly all with blood cell detection subassembly, immunodetection subassembly both keeps mutual isolation and mutual neighbour, the pipeline of connecting between each other also can shorten relatively when avoiding polluting, and the sampling subassembly can directly collect and transport the sample liquid to blood cell detection subassembly and immunodetection subassembly in, its efficiency is higher, and the sample analysis appearance structural configuration that this application provided is reasonable, each parts overall arrangement is tight short, can reduce the volume of sample analysis appearance relatively.

Drawings

In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative efforts, wherein:

FIG. 1 is a schematic block diagram of one embodiment of a sample analyzer provided herein;

FIG. 2 is a schematic view of another angular configuration of the sample analyzer of FIG. 1;

FIG. 3 is a schematic view of a further angle of the sample analyzer of FIG. 1;

FIG. 4 is a schematic structural view of a housing in the sample analyzer of FIG. 1;

fig. 5 is an exploded view of the autosampler assembly and housing of the sample analyzer of fig. 1.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

The terms "first" and "second" in the embodiments of the present application are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present application, the terms "comprise" and "have", as well as any variations thereof, are intended to cover a non-exclusive inclusion. For example, a system, product or apparatus that comprises a list of elements or components is not limited to only those elements or components but may alternatively include other elements or components not expressly listed or inherent to such product or apparatus. In the description of the present application, "plurality" means at least two, e.g., two, three, etc., unless explicitly specifically limited otherwise.

Reference herein to "an embodiment" means that a particular feature, structure, or characteristic described in connection with the embodiment can be included in at least one embodiment of the application. The appearances of the phrase in various places in the specification are not necessarily all referring to the same embodiment, nor are separate or alternative embodiments mutually exclusive of other embodiments. It is explicitly and implicitly understood by one skilled in the art that the embodiments described herein can be combined with other embodiments.

Referring to fig. 1, fig. 1 is a schematic structural diagram of an embodiment of a sample analyzer provided in the present application.

Referring to fig. 1-3, the sample analyzer 100 can be used to perform biological sample analysis, such as blood analysis. This sample analysis appearance 100 includes blood cell detection subassembly 10, immunodetection subassembly 13, sampling subassembly 20, the cold storage subassembly 30 of reagent and determine module 40, sampling subassembly 20 is used for gathering the sample liquid, and blood cell detection subassembly 10 is used for carrying out the blood cell detection to the sample liquid, and immunodetection subassembly 13 is used for carrying out immunodetection to the sample liquid, and the cold storage subassembly 30 of reagent is used for cold-stored reagent, and determine module 40 is arranged in to blood cell detection subassembly formed detect the liquid analysis and detect in order to form the testing information.

Referring to fig. 4, the sample analyzer 100 includes a housing 50, the housing 50 includes a front side plate 51, a rear side plate 52, a first partition plate 53, a second partition plate 54, and a third partition plate 55, the first partition plate 53 is connected between the front side plate 51 and the rear side plate 52, the second partition plate 54 is located at one side of the first partition plate 53 and connected to the front side plate 51, the rear side plate 52, and the first partition plate 53 to form a first space and a second space separated up and down, and the third partition plate 55 is located at the other side of the first partition plate 53 and connected to the front side plate 51, the rear side plate 52, and the first partition plate 53 to form a third space and a fourth space separated up and down.

Referring again to fig. 1 to 3, the blood cell detecting assembly 10 and the immunoassay detecting assembly 13 are both installed in the first space; the sampling assembly 20 includes a mounting plate 21 and a sampling needle 23, the mounting plate 21 is connected to the first partition plate 53, and the sampling needle 23 is used for sucking or discharging a sample liquid and can move along the mounting plate 21 from the external space of the housing 50 to the first space; a reagent refrigeration assembly 30 is mounted in the third space for refrigerating reagents that may be added to the blood cell detection assembly 10 and/or the immunoassay assembly 13; the sensing assembly 40 is installed in the second space.

Furthermore, the reagent refrigeration assembly 30 and the detection assembly 40 are mutually isolated and adjacent to the blood cell detection assembly 10 and the immunity detection assembly 13, pipelines connected with each other can be relatively shortened while pollution is avoided, the sampling assembly 20 can directly collect and transport sample liquid into the blood cell detection assembly 10 and the immunity detection assembly 13, the efficiency is high, the sample analyzer 100 is reasonable in structural layout, all the parts are compact in layout, and the size of the sample analyzer 100 can be relatively reduced.

Referring to fig. 1, the housing 50 includes a bottom plate 56, the bottom plate 56 is connected to the front plate 51, the rear plate 52 and the first isolation plate 53, and the blood cell detecting assembly 10 and the immunoassay detecting assembly 13 are located in the first space and connected to the bottom plate 56.

The blood cell detection assembly 10 and the immunity detection assembly 13 are arranged in sequence along the direction of the mounting plate 21, and the blood cell detection assembly comprises a blood cell reaction tank 11 and a blood cell detection tank 12 which are arranged in sequence along the mounting plate 21, so that the sampling needle 23 can release the sample liquid into the corresponding reaction tanks. The blood cell reaction tank 11 is a five-classification blood cell reaction tank and is used for providing a place for the reaction incubation of blood cells and reagents in blood to form detection liquid which is conveyed to the detection assembly 40 for detection, the detection assembly 40 realizes five-classification detection on the blood cells and detects whether the blood cells in the blood are abnormal or not, so that whether pathology exists in an organism or not is inferred; the blood cell detection pool 12 is a three-classification blood cell detection reaction pool, and the blood cell detection pool 12 is used for providing a place for the reaction incubation of blood cells and reagents in blood, and realizing the three-classification and counting of the blood cells so as to determine whether the cells are abnormal; the immunoassay component 13 is an immunoassay reaction tank, and is used for detecting and counting multiple paths of specific proteins in blood to determine whether the cells are abnormal.

The detection assembly 40 is an optical detection assembly, the detection liquid in the blood cell reaction cell 11 is introduced into the detection assembly 40, and the detection liquid is irradiated by laser to perform operations such as labeling, classifying, counting and the like on blood cells in the detection liquid.

Referring to fig. 3, further, the sample analyzer 100 further includes an injector assembly 60, the injector assembly 60 is connected to a side of the front side plate 51 away from the rear side plate 52, the injector assembly 60 is respectively communicated with the sampling needle 23, the blood cell detection assembly 10, the immunoassay detection assembly 13 and the detection assembly 40 through a pipeline, and can be used to provide power for the sampling needle 23 to suck or release the sample liquid, add a diluent into the blood cell detection assembly 10 and the immunoassay detection assembly 13, and inject the diluent into the detection assembly 40 to form a sheath liquid with the detection liquid for the detection assembly 40 to detect, but is not limited thereto.

The detecting assembly 40 is disposed on the second partition plate 54 and close to the front side plate 51, the mounting plate 21 penetrates through the front side plate 51, and then the distances from the injector assembly 60 to the detecting assembly 40, the sampling assembly 20, the blood cell detecting assembly 10 and the immunoassay detecting assembly 13 are all short, and the injector assembly 60 is disposed outside the housing 50 and does not occupy the inner space of the housing 50, so that the layout of the components on the sample analyzer 100 is more compact, and relatively speaking, the volume thereof is smaller.

The syringe assembly 60 includes a plurality of syringes, for example, three syringes, respectively connected to the sampling needle 23, the blood cell detecting assembly 10, the immunoassay assembly 13 and the detecting assembly 40, for example, the blood cell detecting assembly 10 and the immunoassay assembly 13 share the same syringe for adding the diluent. Alternatively, the number of the syringes is four, wherein the additional syringe is used for conveying the detection liquid in the blood cell reaction cell 11 to the detection assembly 40, and the other syringe is used for injecting the diluent to form a sheath liquid with the detection liquid, so as to facilitate the detection of the detection assembly 40. Alternatively, other power sources may be used to deliver the test fluid into the test assembly 40.

Referring to fig. 3 and 5, the sample analyzer 100 further includes an automatic sample feeding assembly 70, the automatic sample feeding assembly 70 is disposed on a side of the front side plate 51 away from the rear side plate 52, and the automatic sample feeding assembly 70 is configured to send the sample cup to a sample sucking position so as to facilitate sampling by the sampling needle 23. The mounting plate 21 is connected to the first partition 53 and extends out of the housing 50, so that the sampling needle 23 can move inside and outside the housing 50, and further transfer the sample liquid outside the housing 50 into the blood cell detecting assembly 10 and the immunoassay detecting assembly 13.

For example, the mounting plate 21 is provided with a motor, a belt and a guide rail, the motor drives the sampling needle 23 to move on the mounting plate 21 along the guide rail through the belt, and the sampling needle 23 can perform a lifting motion relative to the mounting plate 21, and the lifting motion is driven in the same manner as the aforementioned driving manner for the sampling needle 23 to move along the mounting plate 21. The sampling needle 23 is raised and lowered relative to the mounting plate 21 to aspirate sample fluid from the sample cup or to extend the sampling needle 23 into the blood cell detection assembly 10 and the immunoassay detection assembly 13 and release the sample fluid.

The automatic sample feeding assembly 70 is detachably connected to the housing 50 to facilitate replacement and maintenance of the automatic sample feeding assembly 70. For example, the housing 50 is provided with a mounting beam 57, the bottom side of the automatic sample injection assembly 70 is provided with a slide way surrounded by the guide plate 71, and one end corresponding to the slide way is provided with a baffle plate 72, the slide way is correspondingly sleeved on the mounting beam 57, and the baffle plate 72 is connected with one end of the mounting beam 57.

For example, the bottom side plate of the automatic sample feeding assembly 70 is provided with a plurality of slideways surrounded by the guide plate 41, the housing 50 is provided with a corresponding number of mounting beams 57, the plurality of slideways are correspondingly sleeved on the mounting beams 57, one end of each mounting beam 57 abuts against the baffle 72, and the baffle 72 and the mounting beams 57 are connected by fasteners.

Referring to fig. 2, the sample analyzer 100 further includes a first dosing pump assembly 32, the first dosing pump assembly 32 is disposed in the third space and located between the reagent refrigerating assembly 30 and the rear side plate 52, one end of the first dosing pump assembly 32 is communicated with the reagent refrigerating assembly 30, and the other end of the first dosing pump assembly is communicated with the blood cell detection assembly 10 and/or the immunoassay detection assembly 13, so as to quantitatively add the reagent stored in the reagent refrigerating assembly 30 into the blood cell detection assembly 10 and/or the immunoassay detection assembly 13, thereby avoiding reagent waste and saving cost relatively. For example, the reagent refrigeration assembly 30 stores reagents for detecting specific proteins.

Further, be equipped with reagent on the posterior lateral plate 52 and detect opto-coupler 33, and reagent detects opto-coupler 33 and locates on the pipeline between cold-stored subassembly 30 of reagent and the first quantitative pump package spare 32 for whether have reagent in the detection pipeline, and then judge whether the reagent in the cold-stored subassembly 30 of reagent needs to be changed, further improved sample analyzer 100's automation and intelligent rate. The reagent detection optocoupler 33 is arranged on the rear side plate 52 and above the first dosing pump assembly 32, so that the utilization rate of the third space is further reasonably improved.

A plurality of reagents are stored in the reagent refrigerating assembly 30, when the reagents are used up in a close mode, a large number of bubbles are sucked into the pipeline by the first quantitative pump assembly 32, and when the reagent detection optical coupler 33 detects that bubbles exist in the pipeline, a reagent box connected with the pipeline can be considered to need to be replaced.

The sample analyzer 100 further includes a reagent storage assembly 34, the reagent storage assembly 34 is disposed on a side of the front side plate 51 facing away from the rear side plate 52, and thus the reagent storage assembly 34 does not occupy the volume of the housing 50, which is relatively tight in layout of the components on the sample analyzer 100. A second metering pump assembly 35 is also disposed in the third space, the second metering pump assembly 35 being positioned between the reagent refrigeration assembly 30 and the front plate 51, the second metering pump assembly 35 being adapted to meter the reagent stored in the reagent storage assembly 34 into the blood cell detection assembly 10 and/or the immunoassay detection assembly 13. For example, the reagent storage assembly 34 is used to store reagents that do not require cryogenic storage, such as fluorescent reagents.

One side of the third partition 55 departing from the fourth space is provided with a first air valve set 36, and the first air valve set 36 is connected with the first dosing pump assembly 32 and the second dosing pump assembly 35, and is used for controlling the first dosing pump assembly 32 and the second dosing pump assembly 35 to take materials.

First quantitative pump package spare 32 includes a plurality of quantitative pumps 320 and a plurality of liquid valve 322, a plurality of quantitative pumps 320 pass through leg joint with a plurality of liquid valves 322, and then the installation effectiveness of first quantitative pump package spare 32 has been improved, and the longest limit of liquid valve 322 all along with the direction of height parallel arrangement of posterior lateral plate 52, make first quantitative pump package spare 32 can install the position between reagent refrigeration subassembly 30 and posterior lateral plate 52, it is more reasonable in arranging in the third space, make the utilization ratio in third space higher. The first valve set 36 includes a plurality of air valves 360, and the air valves 360 are in communication with the corresponding fluid valves 322 via tubing to control the air pressure in the tubing to deliver reagents into the blood cell detection assembly 10 and/or the immunoassay detection assembly 13. Furthermore, a pressure-break valve is further disposed on a pipeline through which the reagent enters the blood cell detection assembly 10 and/or the immunoassay assembly 13, and the air valve 360 is further communicated with the corresponding pressure-break valve, so that the corresponding pressure-break valve can control the reagent to enter the blood cell detection assembly 10 and/or the immunoassay assembly 13.

In a specific working state, the pressure-breaking valve is first cut off, the liquid valve 322 is opened and conducted, the corresponding air valve 360 inputs negative pressure into the pipeline, a fixed amount of reagent is taken from the reagent refrigeration assembly 30 through the dosing pump 320, then the reagent enters the pipeline between the liquid valve 322 and the pressure-breaking valve, the liquid valve is closed, then the pressure-breaking valve is opened, and positive pressure is input into the pipeline by the air valve 360, so that the reagent in the pipeline is conveyed into the blood cell detection assembly 10 and/or the immunoassay detection assembly 13.

The structure of the second dosing pump assembly 35 is identical to the structure of the first dosing valve assembly 32 and will not be described in detail.

Referring to fig. 2 again, further, the sample analyzer 100 further includes a waste liquid treatment tank 15, the waste liquid treatment tank 15 is disposed on the rear side plate 52 and is located in the first space, the blood cell detection assembly 10 and the immunoassay detection assembly 13 are both communicated with the waste liquid treatment tank 15 through a pipeline, a pressure break valve 16 is further connected to the pipeline between the blood cell detection assembly 10, the immunoassay detection assembly 13 and the waste liquid treatment tank 15, and the pressure break valve 16 is used for controlling whether waste liquid enters the waste liquid treatment tank 15.

The waste liquid treatment tank 15 is arranged in the first space, and the adjacent blood cell detection assembly 10, the immunoassay assembly 13 and the detection assembly 40 can effectively shorten the pipelines between the waste liquid treatment tank and the blood cell detection assembly 10, the immunoassay assembly 13 and the detection assembly 40, so that liquid drainage is quicker.

The number of the waste liquid treatment tanks 15 may be one or more. For example, the blood cell reaction chamber 11, the blood cell detection chamber 12, and the immunoassay module 13 are all connected to the same waste liquid treatment tank 15. Alternatively, the blood cell reaction chamber 11 and the blood cell detection chamber 12 are communicated with one waste liquid treatment tank 15, and the immunoassay module 13 is communicated with the other waste liquid treatment tank 15.

Further, a window is opened in the rear side plate 52 at a position opposed to the waste liquid treatment tank 15, so that the waste liquid loaded in the waste liquid treatment tank 15 is drawn out through the window.

The sample analyzer 100 further comprises a second air valve set 17 and a right side plate 58, wherein the right side plate 58 is hinged with the rear side plate 52, and the second air valve set 17 is arranged on the right side plate 58 and is communicated with the pressure breaking valve 16. Waste liquid in the blood cell detection assembly 10 and the immunity detection assembly 13 enters a pipeline through a pressure stop valve 16, and positive pressure gas is input into the pipeline through a second gas valve group 17 so as to discharge the waste liquid in the pipeline into a waste liquid treatment tank 15.

The right side plate 58 is hinged with the rear side plate 52, so that the second space is opened through the right side plate 58, and parts in the second space are maintained; mounting the components on the right side plate 58 further makes reasonable use of space within the sample analyzer 100, enabling the sample analyzer 100 to have a smaller volume.

Optionally, the housing 50 further includes a left side panel (not shown) hinged to the rear side panel 52, and the left side panel may be provided with components to facilitate opening of the third space through the left side panel for changing reagent cartridges and the like in the reagent refrigeration assembly 30.

The sample analyzer 100 further comprises an air pump assembly 80 and an air source processing assembly 81, the air pump assembly 80 is located in the second space, the air source processing assembly 81 is disposed on the right side plate 58, the air pump assembly 80 is connected with the air source processing assembly 81 through a pipeline, and the air source processing assembly 81 is connected with the first air valve group 36 and the second air valve group 17.

The air pump assembly 80 is used for providing positive pressure and negative pressure, and the air source processing assembly 81 is used for adjusting the output pressure of the air pump assembly 80 so as to provide the positive pressure or the negative pressure to the pipeline when the positive pressure or the negative pressure required in the pipeline is achieved.

Referring to fig. 1 and 3, a first liquid valve set 18 is disposed on one side of the second partition 54 away from the second space, a second liquid valve set 19 is disposed on one side of the rear side plate 52 facing the front side plate 51, the first liquid valve set 18 is used for controlling a corresponding blood cell detection reagent to enter the blood cell reaction tank 11, and the second liquid valve set 19 is used for controlling a corresponding blood cell detection reagent to enter the blood cell detection tank 12.

Specifically, a reagent interface (not shown) is disposed on a side of the rear side plate 52 away from the front side plate 51, and further, the rear side plate can be connected to an external reagent kit assembly through the reagent interface, so that the sample analyzer 100 provided by the present application can add additional reagents, the types of reagents used by the sample analyzer 100 are more diversified, and the sample analyzer can provide a greater variety of sample analysis and detection experiments; the first valve set 18 is used to control the blood cell detecting reagent corresponding to the blood cell reaction cell 11 to enter the blood cell reaction cell 11, and the second valve set 19 is used to control the blood cell detecting reagent corresponding to the blood cell detection cell 12 to enter the blood cell detection cell 12.

As shown in fig. 4, a circuit board assembly 90 is installed in the fourth space, the circuit board assembly 90 includes a control board 91 and a driving board 92, the driving board 92 is connected to the third partition plate 55, the control board 91 is hinged to the top side of the first partition plate 53 through a connecting assembly 93, a supporting column 94 is supported between the connecting assembly 93 and the third partition plate 55, so that the connecting assembly 93 can cover the driving board 92, and the connecting assembly 93 is detachably connected to the supporting column 94, and further, when the driving board 92 is damaged, the control board 91 and the connecting assembly 93 can be lifted to replace or maintain the driving board 92, which effectively improves the convenience of repairing the driving board 92.

The control board 91 and the driving board 92 are used for controlling the operations of the controlled components on the sample analyzer 100, such as controlling the sampling needle 23 to take and discharge materials, and controlling the operation of the injector assembly 60 and various pumps and valves.

The circuit board assembly 90 is disposed in the fourth space to be isolated from the first space, the second space and the third space, so that the circuit board assembly 90 is prevented from being damaged by leakage of components in other spaces, and the risk of damage to the circuit board assembly 90 is reduced.

The third partition 55 is further provided with a power source 95 at a side facing away from the fourth space, and the power source 95 is a rechargeable power source. Further, the first air valve set 36 is also disposed on a side of the power source 95 facing away from the third partition 55, further utilizing the volume of the third space. Meanwhile, the power supply 95 is disposed at one side away from the first space, so that the risk of short circuit of the power supply due to leakage when a failure occurs on the blood cell detecting assembly 10, the immunodetection assembly 13 or a pipeline is reduced.

Further, a display unit for displaying an analysis result of the sample liquid is further provided on the front side plate 51. For example, the display unit displays an operation interface on which the user selects the function of the sample analyzer 100, so that the sample analyzer 100 automatically performs the detection analysis on the sample liquid.

In contrast to the state of the art, the present application discloses a sample analyzer. Through separating into four spaces with the casing, and with blood cell detection subassembly, immunodetection subassembly and sampling subassembly set up in first space, set up detection subassembly in the second space, set up the cold-stored subassembly of reagent in the third space, wherein second space and third space all are adjacent with first space, make the cold-stored subassembly of reagent, detection subassembly all with blood cell detection subassembly, immunodetection subassembly both keeps mutual isolation and mutual neighbour, the pipeline of connecting between each other also can shorten relatively when avoiding polluting, and the sampling subassembly can directly collect and transport the sample liquid to blood cell detection subassembly and immunodetection subassembly in, its efficiency is higher, and the sample analysis appearance structural configuration that this application provided is reasonable, each parts overall arrangement is tight short, can reduce the volume of sample analysis appearance relatively.

The above description is only an example of the present application and is not intended to limit the scope of the present application, and all modifications of equivalent structures and equivalent processes, which are made by the contents of the specification and the drawings, or which are directly or indirectly applied to other related technical fields, are intended to be included within the scope of the present application.

Claims (14)

1. A sample analyzer, comprising:

the shell comprises a front side plate, a rear side plate, a first partition plate, a second partition plate and a third partition plate, wherein the first partition plate is connected between the front side plate and the rear side plate, the second partition plate is positioned on one side of the first partition plate and is connected with the front side plate, the rear side plate and the first partition plate so as to form a first space and a second space which are vertically separated, and the third partition plate is positioned on the other side of the first partition plate and is connected with the front side plate, the rear side plate and the first partition plate so as to form a third space and a fourth space which are vertically separated;

the blood cell detection assembly and the immunity detection assembly are arranged in the first space and are respectively used for performing blood cell detection and immunity detection on the sample liquid;

a sampling assembly including a mounting plate and a sampling needle, the mounting plate being connected to the first partition plate, the sampling needle being used for sucking a sample liquid or releasing the sample liquid into the blood cell detection assembly and the immunoassay detection assembly, and being movable along the mounting plate from an outer space of the housing into the first space;

a reagent refrigeration assembly mounted within the third space for refrigerating reagents that may be added to the blood cell detection assembly and/or the immunoassay detection assembly;

and the detection assembly is arranged in the second space and is used for analyzing and detecting the detection liquid formed in the blood cell detection assembly.

2. The sample analyzer of claim 1, further comprising an injector assembly, the injector assembly is connected to a side of the front side plate facing away from the rear side plate, the injector assembly is respectively communicated with the sampling needle, the blood cell detection assembly, the immunoassay detection assembly and the detection assembly through pipes, and is configured to provide a power for the sampling needle to suck or release the sample liquid, add a diluent into the blood cell detection assembly and the immunoassay detection assembly, and inject the diluent into the detection assembly to form a sheath liquid with the detection liquid for detection by the detection assembly.

3. The sample analyzer of claim 1, further comprising an autosampler assembly disposed on a side of the front plate facing away from the rear plate, the autosampler assembly configured to deliver a sample cup to a sample suction position for sampling by the sampling needle.

4. The sample analyzer as claimed in claim 3, wherein the housing is provided with a mounting beam, the bottom side of the autoinjection assembly is provided with a slideway surrounded by a guide plate, and a baffle is arranged at one end corresponding to the slideway, the slideway is used for correspondingly sleeving the mounting beam, and the baffle is used for connecting with one end of the mounting beam.

5. The sample analyzer of claim 1, further comprising a first dosing pump assembly disposed in the third space and located between the reagent refrigeration assembly and the rear side plate, wherein the first dosing pump assembly is connected to the reagent refrigeration assembly through a tube, and the first dosing pump assembly is connected to the blood cell detection assembly and/or the immunoassay detection assembly through a tube at one end, and is used for quantitatively adding the reagent stored in the reagent refrigeration assembly to the blood cell detection assembly and/or the immunoassay detection assembly.

6. The sample analyzer as claimed in claim 5, wherein a reagent detection optocoupler is arranged on the rear side plate and arranged on a pipeline between the reagent refrigeration assembly and the first dosing pump assembly for detecting whether a reagent is present in the pipeline and further determining whether the reagent needs to be replaced in the reagent refrigeration assembly.

7. The sample analyzer of claim 5, further comprising a reagent storage assembly disposed on a side of the front plate facing away from the rear plate, wherein a second quantitative pump assembly is further disposed in the third space, the second quantitative pump assembly being located between the reagent refrigeration assembly and the front plate, and the second quantitative pump being configured to quantitatively add a reagent stored in the reagent storage assembly to the blood cell detection assembly and/or the immunoassay assembly.

8. The sample analyzer of claim 7, wherein a side of the second partition plate facing away from the fourth space is provided with a first air valve set, and the first air valve set is connected with the first dosing pump assembly and the second dosing pump assembly and used for controlling the first dosing pump assembly and the second dosing pump assembly to take materials.

9. The sample analyzer of claim 8, further comprising a waste liquid treatment tank disposed on the rear side plate and located in the first space, wherein the blood cell detection assembly and the immunoassay detection assembly are both communicated with the waste liquid treatment tank through pipelines, and a pressure relief valve is connected to the pipelines between the blood cell detection assembly, the immunoassay detection assembly and the waste liquid treatment tank and used for controlling whether waste liquid enters the waste liquid treatment tank or not.

10. The sample analyzer of claim 9 further comprising a second air valve set and a right side plate, the right side plate being hinged to the rear side plate, the second air valve set being disposed on the right side plate and being in communication with the pinch-off valve.

11. The sample analyzer of claim 10, further comprising an air pump assembly and an air source processing assembly, wherein the air pump assembly is located in the second space, the air source processing assembly is disposed on the right side plate, the air pump assembly is connected to the air source processing assembly through a pipe, and the air source processing assembly is connected to the first air valve set and the second air valve set.

12. The sample analyzer as claimed in claim 1, wherein the blood cell detecting component and the immunity detecting component are arranged in sequence along the direction of the mounting plate, wherein the blood cell detecting component comprises a blood cell reaction pool and a blood cell detecting pool which are arranged in sequence along the direction of the mounting plate, the blood cell reaction pool is used for providing blood cells to realize five-classification reaction sites, and the formed detection liquid can be provided for the detecting component, the blood cell detecting pool is used for realizing three-classification and counting of blood cells in blood, and the immunity detecting component is used for realizing detection of multiple paths of specific proteins in blood.

13. The sample analyzer of claim 12, wherein a first set of fluid valves is disposed on a side of the first partition plate facing away from the second space, and a second set of fluid valves is disposed on a side of the rear plate facing the front plate, the first set of fluid valves being configured to control a corresponding blood cell detection reagent to enter the blood cell reaction cell, and the second set of fluid valves being configured to control a corresponding blood cell detection reagent to enter the blood cell detection cell.

14. The sample analyzer of claim 1 wherein the fourth space mounts a circuit board assembly including a control board and a drive board, the drive board being connected to the third spacer, the control board being hinged to the top side of the first spacer by a connecting assembly, a support post being supported between the connecting assembly and the third spacer such that the connecting assembly can cover the drive board.

Images