CN111317561A - Multi-sensing deep thermosetting electrode - Google Patents
Multi-sensing deep thermosetting electrode Download PDFInfo
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- CN111317561A CN111317561A CN201811654630.5A CN201811654630A CN111317561A CN 111317561 A CN111317561 A CN 111317561A CN 201811654630 A CN201811654630 A CN 201811654630A CN 111317561 A CN111317561 A CN 111317561A
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- electrode
- thermosetting
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- catheter
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- 229920001187 thermosetting polymer Polymers 0.000 title claims abstract description 30
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 10
- 239000001301 oxygen Substances 0.000 claims abstract description 10
- 210000004556 brain Anatomy 0.000 claims abstract description 4
- 239000004020 conductor Substances 0.000 claims description 5
- 239000003822 epoxy resin Substances 0.000 claims description 2
- 229920000647 polyepoxide Polymers 0.000 claims description 2
- 230000000659 thermocoagulation Effects 0.000 claims description 2
- 238000002513 implantation Methods 0.000 abstract description 13
- 238000000034 method Methods 0.000 abstract description 9
- 238000012544 monitoring process Methods 0.000 abstract description 7
- 230000000694 effects Effects 0.000 abstract description 3
- 230000015271 coagulation Effects 0.000 description 8
- 238000005345 coagulation Methods 0.000 description 8
- 238000007917 intracranial administration Methods 0.000 description 8
- 230000002490 cerebral effect Effects 0.000 description 6
- 239000000463 material Substances 0.000 description 3
- 210000001519 tissue Anatomy 0.000 description 3
- 206010015037 epilepsy Diseases 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 208000001654 Drug Resistant Epilepsy Diseases 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000005013 brain tissue Anatomy 0.000 description 1
- PRQRQKBNBXPISG-UHFFFAOYSA-N chromium cobalt molybdenum nickel Chemical compound [Cr].[Co].[Ni].[Mo] PRQRQKBNBXPISG-UHFFFAOYSA-N 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 238000009413 insulation Methods 0.000 description 1
- 239000007769 metal material Substances 0.000 description 1
- 238000002324 minimally invasive surgery Methods 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000000602 vitallium Substances 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/03—Measuring fluid pressure within the body other than blood pressure, e.g. cerebral pressure ; Measuring pressure in body tissues or organs
- A61B5/031—Intracranial pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
- A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6867—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive specially adapted to be attached or implanted in a specific body part
- A61B5/6868—Brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00434—Neural system
- A61B2018/00446—Brain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00589—Coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00791—Temperature
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
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- General Health & Medical Sciences (AREA)
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- Plasma & Fusion (AREA)
- Otolaryngology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Optics & Photonics (AREA)
- Neurology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
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Abstract
A multi-sensing deep part thermosetting electrode can realize multi-sensing monitoring in the implantation process and after implantation by adding a plurality of sensors such as a pressure sensor, a temperature sensor, a brain oxygen saturation sensor and the like on an electrode contact and a medical catheter. Through the electrode contacts which are linearly arranged along the direction of the medical catheter and are circumferentially arranged, after a focus position is found, the directional and controllable range thermosetting treatment can be carried out on the focus position, and the electrode lead has low impedance and good thermosetting effect.
Description
Technical Field
The invention discloses a multi-sensing deep-part thermosetting electrode, which realizes the monitoring of the process of implanting the electrode and the acquisition of intracranial pressure, temperature, cerebral oxygen saturation and other signals after implantation by adding various sensors at the electrode part, and can carry out thermosetting treatment in the directional direction and controllable range on a focus position after the focus position is found.
Background
For special epilepsy cases such as intractable epilepsy, besides the need of implanting an electrode to position a focus, a heat coagulation treatment needs to be performed on the focus, and generally, a precise temperature control is needed to realize a small heat coagulation range, so that damage and influence to a functional area or good tissues are avoided as much as possible.
Commercially available deep-section thermocoagulation electrodes are usually implanted by skull minimally invasive surgery, with detailed surgical planning before the surgery is performed, and the implantation process is realized by a stereotactic stent or a surgical robot. During the implantation process, although the surgical risk is reduced to a certain extent by means of the experience of a surgeon or means such as CT/MR, the problems that the electrode punctures the blood vessel, the intracranial physiological signal of a patient needs to be carried out by another sensor or monitoring means, and whether the implantation is in place or not needs to be repeatedly confirmed after the implantation still exist in the whole surgical process.
By means of the multi-sensing technology, the problems can be solved to a certain extent, meanwhile, the operation risk and the operation time are reduced, and the labor intensity of doctors is reduced.
After implantation, when the focal region is treated by heat coagulation, the commercial electrode product usually has higher self impedance, and the electrode conductor generates more heat, so that the heat coagulation effect is influenced to a certain extent, and the consistency of the heat coagulation range of the product is poor. Meanwhile, most products adopt the annular electrode, so that the heat coagulation range is in the circumferential direction of the whole annular electrode, and the heat coagulation treatment in the circumferential directional direction cannot be implemented.
By adding metal with higher conductivity into the conductor material, on one hand, the strength of the conductor material is ensured, and on the other hand, the impedance of the conductor is reduced, so that the thermosetting range of the electrode is more controllable, and the thermosetting effect is better. Meanwhile, by adopting the arrangement of multiple electrode contacts in the same circumferential direction, the heat coagulation treatment in a specific positioning direction can be realized, and good brain tissues can be reserved to the maximum extent.
Disclosure of Invention
The invention provides a multi-sensor low-impedance deep-portion thermosetting electrode which can perform thermosetting treatment in a directional direction. The technical defects of the existing commercial products are made up to a certain extent.
The electrode of the present invention comprises: 1) electrode contacts along the circumferential direction, wherein the electrode contacts are uniformly distributed along the circumferential direction on the same circumference except for being linearly distributed along the direction of the medical catheter at equal intervals; 2) the sensor group comprises a temperature sensor on the inner wall of the electrode contact, a pressure sensor on the side wall of the catheter and a brain oxygen saturation sensor on the side wall of the catheter; 3) the medical catheter is made of polyurethane; 4) and the lead is used for transmitting electrode signals and conducting thermosetting current.
In the embodiment, the electrodes distributed along the circumferential direction can be 3-10 contacts, and 3 groups of electrode contacts are preferably adopted; by reducing the distance between the electrodes, signal acquisition in the directional direction and the thermosetting treatment in the directional direction are realized, and the thermosetting range can be reduced.
Preferably, the shape of the electrode contact may be circular or rectangular.
In some embodiments, a temperature sensor is bonded to the inner wall of the electrode contact for measuring intracranial temperature when implanted, and meanwhile, the temperature in the thermosetting process can be monitored, so that the tissue with good function is effectively protected.
The front end of the catheter is provided with a minimally invasive pressure sensor which is used for monitoring the position of the electrode head end in the implantation process and the intracranial pressure after implantation, and providing intracranial pressure signal monitoring information of a patient in the operation process and the electrode treatment process.
In other embodiments, the side wall of the catheter is further provided with a cerebral oxygen saturation sensor for monitoring intracranial cerebral oxygen saturation information of the patient after the electrode is implanted.
Preferably, the hardness of the medical catheter in the invention is a polyurethane catheter with hardness of more than 55 Shore D, and the inside of the catheter is filled with insulated medical epoxy resin glue after the electrode is assembled, so as to improve the hardness of the electrode implantation part.
Drawings
As shown in fig. 1, the electrode appearance diagram shows the arrangement of the electrode contacts in the direction of the medical catheter, and also shows the positions of the pressure sensor and the cerebral oxygen saturation sensor.
FIG. 2 is a cross-sectional view of the electrode contacts to show the circumferential arrangement;
FIG. 3 is a cross-sectional view of the electrode of FIG. 1 showing the temperature sensor and connecting leads inside the electrode contacts.
Detailed Description
Referring to fig. 1, the electrode contacts 1 are arranged linearly along the axial direction of the medical catheter 2, and there may be 1 to 20 sets of contacts, the contact intervals are equal, and at the same time, there is an opening at the front end of the medical catheter for placing a pressure sensor, which is of an absolute pressure type. Through pressure sensor, when implanting, can judge the position that the head end reachd, implant the completion back simultaneously, can monitor patient's intracranial pressure. The electrode contacts are made of a biocompatible metal material.
On one side of the medical catheter, a cerebral oxygen saturation sensor is also placed to monitor the cerebral oxygen saturation of the patient after implantation.
Fig. 2 is a cross-sectional view of the electrode contact of fig. 1, preferably employing four electrodes 11, 12, 13, 14 circumferentially equispaced. The distribution quantity of the electrode contacts is only one application embodiment, and 3-10 contacts uniformly distributed in the circumferential direction are still in the protection range of the patent.
Fig. 3 is a cross-sectional view of the electrode contact of fig. 1, with a temperature sensor 5 attached to the inner wall of the electrode contact, which can be used to detect intracranial temperature in a patient after implantation. Meanwhile, after the electrode signal determines the focus position, the electrode signal can be used for temperature monitoring during the use of the thermosetting therapy, reliable thermosetting temperature feedback is provided, and damage to other functional areas and good tissues caused by thermosetting is avoided. The lead 6 is shown for transmitting signals and thermosetting current, and the main material is nickel-cobalt-chromium-molybdenum alloy, wherein high-conductivity metal such as silver, gold and the like is added, preferably, the outer diameter of the lead is not more than 0.1mm, and the resistance value of the lead per meter is lower than 100 omega. The outer surface of the lead is provided with an insulating coating, and the insulation resistance is more than 2M omega.
Claims (10)
1. A multi-sensing low-impedance directional deep thermosetting electrode comprises a pressure sensor, a temperature sensor, a brain oxygen saturation sensor and other sensors, and electrode contacts of the multi-sensing low-impedance directional deep thermosetting electrode are distributed at equal intervals along the direction of a linear catheter and are also uniformly distributed along the circumferential direction of the catheter.
2. The deep-section thermodetector of claim 1, wherein the pressure sensor is located at a forward end of the medical catheter, and a catheter pressure sensing window size is less than 1mm long X1mm wide; and the distance from the front end of the conduit is within 5 mm.
3. The deep thermosetting electrode as claimed in claim 1-2, wherein the temperature sensor is located on the inner wall of the electrode contact.
4. The deep thermocoagulation electrode of claim 1 to 3, wherein the brain oxygen saturation is located on a side of the medical catheter.
5. The deep-section thermosetting electrode according to claim 1 to 4, wherein the electrode contacts are arranged along the straight line of the medical catheter, and there may be 2 to 20 sets of electrode contacts.
6. The deep-section thermosetting electrode according to claim 1 to 5, wherein the number of the electrode contacts in the electrode contact group along the same circumferential direction of the medical catheter is 3 to 10.
7. The deep-section thermosetting electrode according to claim 1 to 6, wherein the resistance value per meter of the electrode signal and the thermosetting wire conductor is not more than 100 Ω.
8. The deep-section thermosetting electrode in claim 1-7, wherein the circumferentially arranged electrode contacts can provide more selectable electrode contacts to realize directional thermosetting treatment.
9. The deep-section thermosetting electrode according to claim 1 to 8, wherein the electrode contacts are arranged along the circumference of the medical catheter with a diameter not exceeding 1.5 mm.
10. The deep-section thermosetting electrode according to claim 1 to 9, wherein a medical catheter having a Shore hardness of 55D and an implanted-section catheter at the tip of the electrode are filled with an insulating epoxy resin to increase the hardness of the implanted section.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811654630.5A CN111317561A (en) | 2018-12-14 | 2018-12-14 | Multi-sensing deep thermosetting electrode |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811654630.5A CN111317561A (en) | 2018-12-14 | 2018-12-14 | Multi-sensing deep thermosetting electrode |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN111317561A true CN111317561A (en) | 2020-06-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811654630.5A Pending CN111317561A (en) | 2018-12-14 | 2018-12-14 | Multi-sensing deep thermosetting electrode |
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| Country | Link |
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| CN (1) | CN111317561A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
| CN113598938A (en) * | 2021-09-11 | 2021-11-05 | 北京华科恒生医疗科技有限公司 | Thermosetting electrode |
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| WO2004052182A2 (en) * | 2002-12-11 | 2004-06-24 | Proteus Biomedical, Inc. | Monitoring and treating hemodynamic parameters |
| CN2754557Y (en) * | 2004-12-13 | 2006-02-01 | 谭坤 | Intracranical deep electrode |
| WO2013096913A2 (en) * | 2011-12-23 | 2013-06-27 | Vessix Vascular, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
| CN104605847A (en) * | 2014-01-27 | 2015-05-13 | 北京华科恒生医疗科技有限公司 | Intracranial deep electrode |
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| EP2923666A2 (en) * | 2014-03-27 | 2015-09-30 | Biosense Webster (Israel), Ltd. | Temperature measurement in catheter |
| CN205814415U (en) * | 2016-02-04 | 2016-12-21 | 上海安通医疗科技有限公司 | A kind of multi-electrode radio frequency ablation catheter for renal artery |
| CN106621035A (en) * | 2016-12-09 | 2017-05-10 | 北京品驰医疗设备有限公司 | Directional brain deep electrode capable of suppressing parasitic capacitance |
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| CN108143426A (en) * | 2017-12-26 | 2018-06-12 | 成都拓蓝医疗技术有限公司 | Blood oxygen of brain saturation degree precisely monitors sensor and its monitoring method |
| CN108175386A (en) * | 2018-03-02 | 2018-06-19 | 广州佩迈医学科技有限公司 | Pressure and oxygen content detection probe and detection device in a kind of tissue |
-
2018
- 2018-12-14 CN CN201811654630.5A patent/CN111317561A/en active Pending
Patent Citations (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2004052182A2 (en) * | 2002-12-11 | 2004-06-24 | Proteus Biomedical, Inc. | Monitoring and treating hemodynamic parameters |
| CN2754557Y (en) * | 2004-12-13 | 2006-02-01 | 谭坤 | Intracranical deep electrode |
| WO2013096913A2 (en) * | 2011-12-23 | 2013-06-27 | Vessix Vascular, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
| CN104780836A (en) * | 2012-11-28 | 2015-07-15 | Ad-高科技医疗仪器公司 | Catheter with depth electrode for dual-purpose use |
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| CN107148249A (en) * | 2014-11-19 | 2017-09-08 | 高级心脏疗法公司 | Use the ablating device of high resolution electrode component, system and method |
| CN205814415U (en) * | 2016-02-04 | 2016-12-21 | 上海安通医疗科技有限公司 | A kind of multi-electrode radio frequency ablation catheter for renal artery |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112603536A (en) * | 2020-12-29 | 2021-04-06 | 北京华科恒生医疗科技有限公司 | Method and system for generating electrode thermal coagulation parameters in three-dimensional model |
| CN113598938A (en) * | 2021-09-11 | 2021-11-05 | 北京华科恒生医疗科技有限公司 | Thermosetting electrode |
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Application publication date: 20200623 |