CN111110406A - A shape memory negative Poisson's ratio interbody cage - Google Patents
A shape memory negative Poisson's ratio interbody cage Download PDFInfo
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- CN111110406A CN111110406A CN202010022304.3A CN202010022304A CN111110406A CN 111110406 A CN111110406 A CN 111110406A CN 202010022304 A CN202010022304 A CN 202010022304A CN 111110406 A CN111110406 A CN 111110406A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30075—Properties of materials and coating materials swellable, e.g. when wetted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30092—Properties of materials and coating materials using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30968—Sintering
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/3097—Designing or manufacturing processes using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/3094—Designing or manufacturing processes
- A61F2002/30985—Designing or manufacturing processes using three dimensional printing [3DP]
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- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Prostheses (AREA)
Abstract
本发明公开了一种形状记忆负泊松比椎间融合器，其包括若干个负泊松比结构单元，且负泊松比结构单元通过外界驱动在初始状态和临时状态之间转变；其在临时状态下置入人体病变位置，之后通过外界驱动转化为初始状态实现与病变位置上下表面的充分接触。本发明使用时，首先给椎间融合器一个外界驱动，其体积变小，由于负泊松比结构单元本身具备的压缩侧向反而收缩的独特属性，临时状态的椎间融合器具备更小的体积，因此不需要额外的压缩空间，之后将体积减小后的椎间融合器植入人体内，当其达到病变位置后，再次给其一个外界驱动，负泊松比结构单元发生膨胀导致椎间融合器体积变大，使其在病变位置可与终板有较大的接触面积，促进融合。
The invention discloses a shape memory negative Poisson's ratio intervertebral cage, which comprises several negative Poisson's ratio structural units, and the negative Poisson's ratio structural units are driven by the outside to transform between an initial state and a temporary state; It is placed in the lesion position of the human body in a temporary state, and then converted into an initial state through external driving to achieve full contact with the upper and lower surfaces of the lesion position. When the present invention is used, the intervertebral cage is first driven by an external drive, and its volume becomes smaller. Due to the unique property of compressing laterally but contracting the negative Poisson's ratio structural unit itself, the intervertebral cage in the temporary state has a smaller size. volume, so no additional compression space is needed, and then the reduced volume of the interbody cage is implanted into the human body. When it reaches the lesion position, it is given an external drive again, and the negative Poisson’s ratio structural unit expands, causing the vertebral column The volume of the cage becomes larger, so that it can have a larger contact area with the endplate at the location of the lesion and promote fusion.
Description
Technical Field
The invention belongs to the technical field of medical instruments, and particularly relates to a shape memory negative Poisson's ratio interbody fusion cage.
Background
The intervertebral fusion is an effective method for treating degenerative disc diseases, can greatly relieve the pain of patients and carry out functional repair; the design and application of the intervertebral fusion cage in the eighties of the last century realize the integration function of fusion and fixation, and the design and application are greatly popularized.
However, most of the currently clinically applied intervertebral fusion cages are only suitable for open fusion surgery due to the limitations of implantation size, contact area and the like, and the intervertebral fusion cages need to be extensively stripped and pulled to soft tissues such as paraspinal muscles and the like during the surgery, so that the intervertebral fusion cages bleed too much during the surgery, the spinal nerves can be damaged, and chronic low back pain is easy to occur after the surgery.
Therefore, the selection of an ideal intervertebral cage plays an important role in the success of the fusion, but for minimally invasive fusion, it is difficult to balance the implantation volume and the fusion area of the cage; the small-volume fusion cage can cause less damage to a patient in an operation, but if the contact area of the fusion cage and a vertebral body end plate is too small, the end plate is easy to collapse, the stability is reduced, and the fusion rate is reduced.
Disclosure of Invention
In order to solve the problems, the invention provides a shape memory negative poisson ratio interbody fusion cage which is more suitable for minimally invasive surgery and has better fusion rate compared with the traditional fusion cage.
The technical scheme adopted by the invention is as follows:
a shape memory negative Poisson ratio interbody fusion cage comprises a plurality of negative Poisson ratio structural units, wherein the negative Poisson ratio structural units are arranged in rows and columns; the negative Poisson ratio structural unit is driven by the outside to be converted between an initial state and a temporary state; the temporary state is placed in the pathological change position of the human body, and then the temporary state is converted into an initial state through external driving to realize full contact with the upper surface and the lower surface of the pathological change position.
Preferably, the negative poisson's ratio structural unit is formed by adopting shape memory polymer, shape memory alloy and filler.
Preferably, the shape memory polymer is one or a combination of more than one of shape memory polyether ether ketone, shape memory polyether ketone, shape memory epoxy resin or shape memory polylactic acid.
Preferably, the shape memory alloy is one or the combination of two of shape memory nickel-titanium alloy and shape memory titanium-based alloy.
Preferably, the filler is one or more of hydroxyapatite, β -tricalcium phosphate, titanium dioxide and carbon fiber.
Preferably, the adjacent negative poisson's ratio structural units are arranged in a staggered mode, so that cavities for placing implanted bones are formed on two sides of the shape memory negative poisson's ratio interbody fusion cage.
Preferably, the shape memory negative poisson's ratio interbody fusion cage further comprises an anti-slip unit, wherein the anti-slip unit is positioned on the outer surface of the negative poisson's ratio structural units arranged in rows and columns;
the anti-skid unit is one or a combination of more than one of a first anti-skid structure, a second anti-skid structure and a third anti-skid structure;
or,
the antiskid unit is octopus sucking disc structure, tree frog callus on the sole structure or gecko foot structure.
Preferably, the shape memory negative poisson's ratio interbody fusion cage further comprises a threaded hole for connecting with an external conveying device, and the threaded hole is formed in the side surface of the interbody fusion cage formed after the negative poisson's ratio structural units are arranged in rows and columns.
Preferably, the negative poisson's ratio structural unit is one of a concave hexagonal honeycomb structure, a concave triangular structure, a star-shaped structure, a rotating triangular structure, a rotating rectangular structure, a hand-shaped structure, an inverse hand-shaped structure, a diamond-shaped structure and a rectangular structure.
Preferably, the shape memory negative poisson's ratio interbody fusion cage is molded by 4D printing.
Preferably, the external drive is one of a temperature drive, a magnetic drive, a solution drive or an optical drive.
Compared with the prior art, when the intervertebral fusion cage is used, an external drive is firstly provided for the intervertebral fusion cage, the volume of the intervertebral fusion cage is reduced, the intervertebral fusion cage with the shape memory can obtain a larger volume change rate because the negative poisson ratio structural unit has an abnormal phenomenon of expansion (the side direction is expanded when being stretched and the side direction is contracted when being compressed), then the intervertebral fusion cage with the reduced volume is implanted into a human body by adopting a minimally invasive method, and after the intervertebral fusion cage reaches the pathological change position, the external drive is provided for the intervertebral fusion cage again, the negative poisson ratio structural unit expands to cause the volume of the intervertebral fusion cage to be increased, so that the intervertebral fusion cage can have a larger contact area with the upper end plate and the lower end plate at the pathological change position, and the fusion can be.
Drawings
FIG. 1 is a schematic structural view of a shape memory negative Poisson's ratio intervertebral cage in an initial configuration according to an embodiment of the present invention;
FIG. 2 is a front view of FIG. 1;
FIG. 3 is a top view of FIG. 1;
FIG. 4 is a side view of FIG. 1;
FIG. 5 is a schematic structural view of a shape memory negative Poisson's ratio interbody cage in a temporary configuration according to an embodiment of the present invention;
fig. 6 is a top view of fig. 5.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is described in further detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In the description of the present invention, it is to be understood that the terms "vertical", "lateral", "longitudinal", "front", "rear", "left", "right", "upper", "lower", "horizontal", and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience of description of the present invention, and do not mean that the device or member to which the present invention is directed must have a specific orientation or position, and thus, cannot be construed as limiting the present invention.
In the description of the present invention, it should be noted that, unless otherwise explicitly specified or limited, the terms "mounted," "connected," and "connected" are to be construed broadly, e.g., as meaning either a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; may be directly connected or indirectly connected through an intermediate. The specific meanings of the above terms in the present invention can be understood in specific cases to those skilled in the art.
The embodiment of the invention provides a shape memory negative Poisson ratio interbody fusion cage, which comprises a plurality of negative Poisson ratio structural units 1, wherein the negative Poisson ratio structural units 1 are arranged in rows and columns; and the negative poisson ratio structural unit 1 is driven by the outside to be converted between an initial state and a temporary state; the temporary state is placed in a pathological change position of a human body, and then the temporary state is converted into an initial state through external driving to realize full contact with the upper surface and the lower surface of the pathological change position;
a negative poisson's ratio structure is one that expands laterally in the elastic range when stretched; and when compressed, it contracts laterally.
Thus, through the structure, firstly, the intervertebral fusion cage is externally driven, the volume of the intervertebral fusion cage is reduced, and because the negative Poisson's ratio structural unit 1 has an abnormal phenomenon of expansion, namely stretching, the lateral direction (the direction vertical to the stress direction) is expanded (the normal material laterally contracts); when the intervertebral fusion cage is compressed, the side direction also contracts (the normal material expands laterally), the whole volume is reduced more due to the lateral contraction, so that an additional compression space is not needed, the intervertebral fusion cage with the reduced volume is implanted into a human body, after the intervertebral fusion cage reaches a pathological change position, the intervertebral fusion cage is driven by one external environment again, the negative poisson ratio structural unit 1 expands to enlarge the volume of the intervertebral fusion cage, so that the intervertebral fusion cage can have a larger contact area with an end plate at the pathological change position, and the fusion can be promoted.
The negative Poisson ratio structural unit 1 is composed of shape memory polymer, shape memory alloy and filler.
The shape memory polymer is one or the combination of more than one of shape memory polyether ether ketone, shape memory polyether ketone, shape memory epoxy resin or shape memory polylactic acid.
The shape memory alloy is one or the combination of two of shape memory nickel-titanium alloy and shape memory titanium-based alloy.
The filler is one or the combination of more than one of hydroxyapatite, β -tricalcium phosphate, titanium dioxide and carbon fiber.
In this embodiment, the intervertebral cage is made of a thermotropic shape memory polymer, when the shape memory polymer is heated to a temperature higher than the glass transition temperature (T > Tg), the material is transformed from a glassy state to a rubbery state, the modulus is reduced, and at this time, the rubbery shape memory polymer is given a temporary shape by an external force, the external force is maintained, the temperature is rapidly reduced below the glass transition temperature (T < Tg), the temporary shape is fixed, and the shape memory polymer automatically returns to the original shape by heating again (T > Tg);
also, in this embodiment, the temperature at which the thermotropic shape-memory polymer undergoes a shape change (glass transition temperature) ranges from 40 to 80 degrees.
The adjacent negative Poisson ratio structural units 1 are arranged in a staggered manner, so that cavities 2 for placing implanted bones are formed on two sides of the shape memory negative Poisson ratio interbody fusion cage;
in this embodiment, the negative poisson's ratio structural unit 1 is a concave hexagonal structure, that is, any two groups of opposite sides of the hexagon are inclined towards the center of the hexagon;
specifically, 40 negative poisson ratio structural units 1 are arranged to form ten rows and ten columns, the first, third, fifth, seventh and ninth columns are correspondingly arranged, the second, fourth, sixth, eighth and tenth columns are correspondingly arranged, and adjacent columns are arranged in a staggered manner; in this way the second column is offset from the adjacent first and third columns, as shown, i.e. the starting negative poisson's ratio structural unit 1 of the second column is further back in relation to the starting negative poisson's ratio structural unit 1 of the first and third columns, so that a first cavity 21 is formed between the first and third columns;
The shape memory negative Poisson ratio interbody fusion cage further comprises an anti-slip unit 3, wherein the anti-slip unit 3 is positioned on the outer surface of the negative Poisson ratio structural units 1 arranged in rows and columns; the antiskid unit 3 is one or more of a first antiskid structure 31, a second antiskid structure 32 and a third antiskid structure 33;
the first anti-slip structure 31, the second anti-slip structure 32 and the third anti-slip structure 33 may be bosses with different shapes and sizes, or may be bionic anti-slip structures including an octopus-like suction cup structure, a wood frog foot pad structure, a gecko foot structure and the like, or may be anti-slip structures on foot pads in daily use, and certainly, are not limited to the above structures;
the anti-skid structures with different shapes are arranged, so that friction forces with different sizes are achieved, and under the condition that one anti-skid structure fails, a spare anti-skid structure can be selected.
The shape memory negative Poisson ratio interbody fusion cage further comprises a threaded hole 4 used for being connected with an external conveying device, and the threaded hole 4 is formed in the side surface of the interbody fusion cage formed after the plurality of negative Poisson ratio structural units 1 are arranged in a row;
therefore, the intervertebral fusion device is connected with the minimally invasive implantation conveying device through the threaded hole 4, and the whole minimally invasive surgery can be completed.
The negative Poisson ratio structural unit 1 is of one of a concave hexagonal honeycomb structure, a concave triangular structure, a star-shaped structure, a rotating triangular structure, a rotating rectangular structure, a hand-shaped structure, an inverse hand-shaped structure, a diamond-shaped structure and a rectangular structure;
specifically, a concave hexagon is that any two groups of opposite sides of the hexagon are inclined towards the center of the hexagon; one side of the concave triangle, namely the triangle, is of an arc structure, and the circle center of the circle where the arc is located is positioned outside the triangle.
The shape memory negative Poisson's ratio interbody fusion cage is formed by 4D printing;
4D printing is the combination of a 3D printing technology and a shape memory polymer/shape memory alloy; the 3D printing method used comprises: selective Laser Sintering (SLS), Fused Deposition Modeling (FDM), Selective Laser Melting (SLM), or Electron Beam Melting (EBM).
Specifically;
in one embodiment, the shape memory material used is shape memory nickel-titanium alloy, and the 3D printing method used is Selective Laser Sintering (SLS);
the method comprises the steps of guiding a pre-built negative Poisson ratio interbody fusion cage model into a printer system, filling shape memory nickel-titanium alloy powder into a powder supply cylinder of an SLS system, absorbing laser energy by the shape memory nickel-titanium alloy powder under the assistance of a computer, melting and then solidifying the shape memory nickel-titanium alloy powder, and sintering and stacking the shape memory nickel-titanium alloy powder layer by layer to form the three-dimensional interbody fusion cage.
In another embodiment, the used material is shape memory polyetheretherketone, and the adopted 3D printing method is fused deposition molding;
adding powder, particles or blocky shape memory polyether-ether-ketone into a multistage extruder, obtaining a shape memory polyether-ether-ketone wire with a certain diameter (usually 1.75mm) at a discharge port, wherein the wire is a raw material for fused deposition molding, and obtaining the three-dimensional shape memory polyether-ether-ketone negative Poisson ratio intervertebral fusion cage in a layer-by-layer deposition mode through computer assistance.
In another embodiment, the used materials are shape memory polylactic acid, shape memory polyether ether ketone and hydroxyapatite, and the adopted 3D printing method is fused deposition molding;
the three raw materials of powder, particles or blocks are fully mixed (molten or solvent), and granulated (composite material particles of the three materials), finally, a wire material required by fused deposition molding is obtained by extrusion of an extruder, and then the three-dimensional structure of the shape memory polymer composite material negative poisson ratio interbody fusion cage is obtained by the fused deposition molding.
In another embodiment, shape memory polylactic acid and shape memory polyether ether ketone are used as matrix materials, carbon fiber is used as a reinforcing material, and a 3D printing method is adopted for fused deposition molding; adding powder, particles or blocky shape memory polyether-ether-ketone into a multistage extruder, obtaining a shape memory polyether-ether-ketone wire with a certain diameter (usually 1.75mm) at a discharge port, conveying carbon fibers by using a special wire feeding mechanism during fused deposition printing, laying according to a pre-designed carbon fiber path, and obtaining the three-dimensional structure of the shape memory polymer carbon fiber composite material negative poisson ratio interbody fusion cage in a mode of depositing a matrix material layer by layer.
The external drive is one of temperature drive, magnetic drive, solution drive or optical drive;
thus, the transition between the initial and temporary forms can be achieved by temperature, magnetic, solution or optical actuation.
Specifically, taking the shape memory deformation process of the 4D printed shape memory nickel-titanium alloy negative Poisson's ratio intervertebral fusion device as an example, the temperature is reduced to the deformation temperature (A)fMartensite reverse transformation finishing temperature), and applying external force to shape the shape memory nickel-titanium alloy negative poisson ratio intervertebral fusion device into a contracted state, and keeping the shape fixed after unloading; then carrying out minimally invasive implantation process, and raising the temperature to the deformation temperature (A) after reaching the implantation positionf) Above, the shape memory nickel-titanium alloy negative poisson ratio intervertebral fusion device returns to the initial shape, and plays the role of fusion and fixation.
The height of the temporary form is small, so that the intervertebral fusion cage is conveniently implanted into a human body to realize minimally invasive operation; the height of the initial state is high, so that the intervertebral fusion cage can be fully contacted with the upper surface and the lower surface of a lesion after reaching the lesion position, and better fusion is realized.
The working process is as follows:
before the minimally invasive fusion surgery is performed by adopting the interbody fusion cage provided by the embodiment, the artificial bone or the autogenous bone is placed in the cavity component 2, certain external drive is applied (for example, the temperature is higher than the glass transition temperature of the used shape memory polymer and the composite material thereof), at the moment, the negative poisson's ratio structural unit 1 is compressed, the interbody fusion cage is contracted to a temporary shape with a small volume, the external force is maintained unchanged, the interbody fusion cage is rapidly cooled to be below the glass transition temperature, the temporary shape is fixed, and at the moment, the compressed shape memory polymer interbody fusion cage can be conveyed by the minimally invasive fusion surgery conveying device;
when a minimally invasive surgery is performed, the minimally invasive fusion surgery conveying device is connected with the threaded hole 4, after the conveying device reaches a preset position, corresponding external stimulation is given again, the negative Poisson's ratio structural unit 1 in a compressed state automatically returns to the original shape and height, the fusion and fixation effects are exerted, the shape memory polymer intervertebral fusion cage is completely released, and the conveying device is withdrawn.
In the embodiment, the shape memory negative poisson ratio interbody fusion cage is printed by adopting a 4D printing technology, is suitable for minimally invasive fusion, and has the advantages of small tissue damage, less bleeding in the operation and quick postoperative recovery; the shape memory material is combined with the structure with unique mechanical property for measuring the negative Poisson ratio to obtain larger volume ratio before and after deformation, on one hand, the wound is small during minimally invasive implantation, and on the other hand, the initial volume is recovered after implantation to provide larger contact area of end plates and promote fusion; and the upper surface and the lower surface adopt a bionic anti-slip structure, so that slipping is prevented, and the stability is improved.
The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.
Claims (10)
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| CN202010022304.3A CN111110406A (en) | 2020-01-09 | 2020-01-09 | A shape memory negative Poisson's ratio interbody cage |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112080669A (en) * | 2020-09-07 | 2020-12-15 | 吉林大学 | NiTi shape memory alloy with energy absorption and vibration reduction functions and preparation method and application thereof |
| CN112932746A (en) * | 2021-04-06 | 2021-06-11 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | Bone filling member and filling method |
| CN113679515A (en) * | 2021-07-01 | 2021-11-23 | 广州恒尚科技有限公司 | Hip joint prosthesis based on shape memory alloy porous microstructure |
| IT202300003558A1 (en) * | 2023-02-28 | 2024-08-28 | Univ Degli Studi Di Modena E Reggio Emilia | SPINAL PROSTHESIS |
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| CN112080669A (en) * | 2020-09-07 | 2020-12-15 | 吉林大学 | NiTi shape memory alloy with energy absorption and vibration reduction functions and preparation method and application thereof |
| CN112080669B (en) * | 2020-09-07 | 2022-01-14 | 吉林大学 | NiTi shape memory alloy with energy absorption and vibration reduction functions and preparation method and application thereof |
| CN112932746A (en) * | 2021-04-06 | 2021-06-11 | 中山大学肿瘤防治中心（中山大学附属肿瘤医院、中山大学肿瘤研究所） | Bone filling member and filling method |
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| WO2024180478A1 (en) * | 2023-02-28 | 2024-09-06 | Universita' Degli Studi Di Modena E Reggio Emilia | Vertebral prosthesis |
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