CN111035432A

CN111035432A - A thrombus cleaning brush device

Info

Publication number: CN111035432A
Application number: CN202010110194.6A
Authority: CN
Inventors: 卢长青; 卢淑欣; 汤建民; 刘波; 贾合磊
Original assignee: Henan University of Traditional Chinese Medicine HUTCM
Current assignee: Henan University of Traditional Chinese Medicine HUTCM
Priority date: 2020-02-23
Filing date: 2020-02-23
Publication date: 2020-04-21

Abstract

A thrombus cleaning brush device, comprising a guide wire and a micro-catheter, the guide wire is installed in the micro-catheter, the guide wire is composed of a core and a sheath outside the core, and the sheath includes a spiral sheath and a coating sheath , the helical sheath is spirally wrapped around the core of the guide wire head, the coating sheath is covered outside the core of the guide wire tail, the core of the brush part is covered with a helical guide wire, and the helical guide wire is evenly clamped Holding the brush that radiates outward, the present invention has simple structure, convenient operation, low cost, can be mass-produced, can effectively clean the thrombus in blood vessels, avoid damage to the intima of blood vessels caused by repeated operations, can be reused, social and economical The benefits are significant.

Description

Thrombus cleaning brush device

Technical Field

The invention relates to the field of medical instruments, in particular to a thrombus cleaning brush device.

Background

With the advent of aging society, the incidence of atherosclerotic diseases is increasing, because atherosclerotic plaques cause vascular lumen stenosis, once plaques become inflamed or ruptured, blood clots, namely thrombosis, can be formed at the damaged parts of the inner surfaces of blood vessels, blood vessel lumens can be suddenly narrowed and aggravated, even acute occlusion can be caused, once the vascular lumen stenosis is aggravated, even the occlusion is caused, acute ischemia and anoxia of tissues and organs in a blood supply area can be caused, even necrosis can be caused, cerebral infarction can be caused when the vascular lumen stenosis is aggravated, acute myocardial infarction can be formed when the vascular lumen stenosis is generated in the heart, and the vascular stenosis can also be generated in other organ vessels of the whole body, belongs to clinical emergencies, becomes a large class of diseases which seriously threaten human health in the current society, consumes a large amount of medical resources, and brings heavy economic burden to the society.

The most effective treatment of acute ischemic vascular diseases is to allow the blocked blood vessels to be passed through as early as possible, remove thrombus generated in the blood vessels at the early stage and allow the blocked blood vessels to be passed through, and in order to solve the problem that the blood vessels are blocked by thrombus, the traditional method is to place an arterial sheath after the puncture of femoral artery or radial artery is successful under the X-ray fluoroscopy, send a guide catheter with the diameter of 6F-7F to the opening of a target artery along the blood vessels under the guide of a guide wire, send the guide catheter into a thrombus suction catheter under the guide of the guide wire, send the guide catheter to the thrombus part, directly give negative pressure and extract the thrombus.

Although thrombus suction catheters produced by several companies are clinically applied at home and abroad at present, due to the structural problems, the thrombus suction catheters have limited diameters and are easy to block, and the thrombus suction effect is not ideal, in order to overcome the problems, in recent years, recoverable stents (mechanical thrombus removal) are rapidly developed and are successively applied to clinic, a plurality of mechanical thrombus removal stents are put on the market at present, although the stents have slight changes in design, the principle and the use are similar, the recoverable self-expandable structural stent is arranged in a microcatheter in advance, the microcatheter carrying the stent is sent to the thrombus far end at the position of an occluded blood vessel along a guide wire, the stent is released and expanded for 2 to 4 minutes, after the stent is fused with the thrombus, the stent and the microcatheter are withdrawn simultaneously, the thrombus can be taken out and can be removed repeatedly, generally three times, although the thrombus removal effect is improved compared with thrombus suction, however, repeated thrombus removal causes embolus displacement or local vascular intimal injury, so a thrombus cleaning device which is simpler and more effective and is convenient to operate is clinically needed, but at present, the thrombus cleaning device in China is few, and therefore, the research and development of the thrombus cleaning device become a technical problem which needs to be solved urgently.

Disclosure of Invention

Aiming at the problems, the invention aims to provide a thrombus cleaning brush device, which can effectively solve the problems that the existing thrombus cleaning device has unsatisfactory thrombus suction effect and complex operation and is easy to damage the intravascular membrane.

In order to achieve the purpose, the technical scheme includes that the thrombus cleaning brush device comprises a guide wire and a microcatheter, the guide wire is arranged in the microcatheter and comprises a core and a sheath outside the core, the sheath comprises a spiral sheath and a coating sheath, the spiral sheath is spirally wound and covers the core at the head of the guide wire, the coating sheath covers the core at the tail of the guide wire, the core at the brush part is sleeved with the spiral guide wire, and the spiral guide wire is uniformly clamped with a brush which radiates outwards.

The invention has simple structure, convenient operation and low cost, can be produced in batches, can effectively clean thrombus in blood vessels, avoids injury to intima of blood vessels caused by repeated operation, can be repeatedly used and has remarkable social and economic benefits.

Drawings

FIG. 1 is a schematic diagram of the present invention.

Fig. 2 is a schematic view of a guidewire structure of the present invention.

FIG. 3 is a schematic view of the structure of the microcatheter of the present invention.

Fig. 4 is a use state diagram of the present invention.

Detailed Description

The following detailed description of the embodiments of the invention is provided in connection with the accompanying drawings and the detailed description.

The invention provides a thrombus cleaning brush device which is provided with a guide wire and a microcatheter, wherein the guide wire 1 is arranged in the microcatheter 6, the guide wire 1 is composed of a core 2 and a sheath outside the core 2, the sheath comprises a spiral sheath 3-1 and a coating sheath 3-2, the spiral sheath 3-1 is spirally wound and covered outside the core 2 of the head 1-1 of the guide wire 1, the coating sheath 3-2 is covered outside the core 2 of the tail 1-3 of the guide wire 1, the core 2 of the brush part 1-2 is sleeved with a spiral guide wire 4, and the spiral guide wire 4 is uniformly clamped with a brush 5 which radiates outwards.

In order to ensure better implementation effect, the diameter of the guide wire 1 is 0.36mm, the length of the head part 1-1 is 15-20mm, the length of the brush part 1-2 is 15-20mm, and the length of the tail part 1-3 is 1700-1800 mm.

The core 2 is made of 304 stainless steel or nickel-titanium alloy material and is round.

The spiral sheath 3-1 is a spring ring sheath made of platinum alloy or a sheath made of tungsten-containing polymer and is impermeable to X rays.

The coating sheath 3-2 is made of polytetrafluoroethylene which is sprayed on the outside of the core 2 of the tail part 1-3 of the guide wire 1.

The brush 5 is round and made of carbon nano fiber or absorbent cotton thread and nylon fiber, the diameter of the end part of the brush 5 is 5-8mm when the brush is opened, and the diameter of the brush 5 is 0.5-1.0mm when the brush is contracted.

The spiral sheath 3-1 and the core 2 are coated with a hydrophilic coating or a hydrophobic coating.

The spiral guide wire 4 is formed by spirally winding double guide wires or multiple guide wires.

The length of the micro catheter 6 is 1300-1500mm, the inner diameter is not less than 1.1mm, the outer diameter is not more than 1.43mm, the micro catheter comprises a catheter seat 6-1 and a catheter body 6-2, the catheter body 6-2 is divided into an inner layer 6-23, a braided layer 6-22 and an outer layer 6-21 from inside to outside, the outer layer 6-21 is made of one or more of 3 polyester materials of nylon, polyether block polyamide (pebax) and thermoplastic polyurethane elastomer rubber (tpu) in a matched mode, the braided layer 6-22 is made of 12-20 heat-treated 304 stainless steel flat wire materials which are braided into a net shape, the braiding density is 60-100ppi, the inner layer 6-23 is made of polytetrafluoroethylene (ptfe), the wall thickness of the catheter body 6 is not more than 0.33mm, the outer surface of the catheter body 6 is coated with a hydrophilic coating, the outer peripheral surface of the head of the catheter body 6 is provided with a radiopaque marker band 7 with the width of 2-4, the catheter position can be clearly observed and judged by X-ray perspective, the catheter seat 6-1 is a horn-shaped hollow circular tube made of nylon, and the circular part of the catheter seat 6-1 is communicated with the tail part of the catheter body 6.

When the invention is used in concrete, the head end covered with the spiral sheath is soft and easy to plasticity, and can provide good tactile feedback, no matter the platinum alloy coil sheath or the sheath made of the polymer containing tungsten is not permeable to X rays, firstly, an additional guide catheter is sent to the opening of a target blood vessel, an additional extension catheter is pushed to the proximal end of thrombus along the guide catheter, then the guide wire with the thrombus cleaning brush is retracted into the microcatheter for standby under the contraction state, the head part of the guide wire is in front, the guide wire and the microcatheter are sent to the distal end of thrombus from the guide catheter through the extension catheter, the tail part of the guide wire is fixed in vitro, the microcatheter is withdrawn and extracted, the brush on the guide wire is in the opening state, then the tail part of the guide wire and the microcatheter are withdrawn in vitro, the guide wire and the microcatheter are close to or enter the extension catheter, the brush on the guide wire are withdrawn outwards together with the thrombus, finally, the whole body together with the extension catheter is withdrawn out of the body to finish the thrombus removal, and the operation can be repeated if necessary.

The thrombus removal device has the advantages of simple structure, convenient operation and low cost, can be produced in batch, meets the requirement of accurate thrombus removal in narrow blood vessels, is a great innovation of the thrombus removal device, and has remarkable social and economic benefits.

Claims

1. A thrombus cleaning brush device, comprising a guide wire and a micro-catheter, wherein the guide wire (1) is housed in the micro-catheter (6), and the guide wire (1) consists of a core (2) and a core A sheath outside the core (2) is formed, the sheath includes a spiral sheath (3-1) and a coating sheath (3-2), and the spiral sheath (3-1) is helically wound to cover the head of the guide wire (1) Outside the core (2) of the part (1-1), the coating sheath (3-2) covers the outside of the core (2) of the tail part (1-3) of the guide wire (1), and the brush part (1- 2) The core (2) is sleeved with a spiral guide wire (4), and a brush (5) radiating outward is evenly clamped on the spiral guide wire (4).

2 . The thrombus cleaning brush device according to claim 1 , wherein the diameter of the guide wire ( 1 ) is 0.36 mm, the length of the head ( 1-1 ) is 15-20 mm, and the brush part ( 1 ) -2) The length is 15-20mm, and the length of the tail (1-3) is 1700-1800mm.

3 . The thrombus cleaning brush device according to claim 1 , wherein the core ( 2 ) is a circular shape made of 304 stainless steel or nickel-titanium alloy material. 4 .

The thrombus cleaning brush device according to claim 1, characterized in that, the spiral sheath (3-1) is a coil sheath made of platinum alloy or a sheath made of tungsten-containing polymer Cover, not transparent to X-rays.

5. The thrombus cleaning brush device according to claim 1, wherein the coating sheath (3-2) is made of polytetrafluoroethylene sprayed on the tail (1-3) of the guide wire (1). Outside the core (2).

6 . The thrombus cleaning brush device according to claim 1 , wherein the brush ( 5 ) is a circular shape made of carbon nanofibers or absorbent cotton threads and nylon fibers or absorbent wool, and the brush ( 5) The diameter of the end is 5-8mm when it is opened, and 0.5-1.0mm when it is contracted.

The thrombus cleaning brush device according to claim 1 or 4, characterized in that, the helical sheath (3-1) and the core (2) are coated with a hydrophilic coating or a hydrophobic coating.

8 . The thrombus cleaning brush device according to claim 1 , wherein the helical guide wire ( 4 ) is constituted by double guide wires or multiple guide wires spirally wound. 9 .

9. The thrombus cleaning brush device according to claim 1, wherein the micro-catheter (6) has a length of 1300-1500 mm, an inner diameter of not less than 1.1 mm, an outer diameter of not more than 1.43 mm, and is formed by a catheter holder (6). -1) and the catheter body (6-2), the catheter body (6-2) is divided into an inner layer (6-23), a braided layer (6-22) and an outer layer (6-21) from the inside to the outside. The layer (6-21) is made of one or more of the three polyester materials of nylon, polyether block polyamide and thermoplastic polyurethane elastomer rubber, and the braided layer (6-22) is 12-20 pieces. The heat-treated 304 stainless steel flat wire material is braided into a mesh, the braiding density is 60-100ppi, the inner layer (6-23) is made of polytetrafluoroethylene, and the wall thickness of the catheter body (6) does not exceed 0.33mm , the outer surface of the catheter body (6) is coated with a hydrophilic coating, the outer peripheral surface of the head of the catheter body (6) is provided with a radiopaque marking tape (7) with a width of 2-4mm, and the catheter seat (6-1) is A trumpet-shaped hollow circular tube made of nylon, the circular part of the catheter holder (6-1) is communicated with the tail of the catheter body (6).