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CN110946569B - Multichannel body surface electrocardiosignal synchronous real-time acquisition system - Google Patents

Multichannel body surface electrocardiosignal synchronous real-time acquisition system Download PDF

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CN110946569B
CN110946569B CN201911347394.7A CN201911347394A CN110946569B CN 110946569 B CN110946569 B CN 110946569B CN 201911347394 A CN201911347394 A CN 201911347394A CN 110946569 B CN110946569 B CN 110946569B
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CN110946569A (en
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毛威
周鑫斌
陈晨
王志军
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Zhejiang Hospital
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    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
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Abstract

The invention discloses a multichannel body surface electrocardiosignal synchronous real-time acquisition system, which comprises a 64-lead body surface electrocardiogram acquisition integrated box and an electrocardio-lead patch; the 64-lead body surface electrocardiogram acquisition integrated box is formed by connecting 8 10-channel dynamic electrocardiogram recording boxes in parallel, and acquires 64-channel body surface electrocardiograms synchronously and in real time. The invention adopts 64 multi-lead body surface electrode positions optimized by clinical data to fully and completely reflect body surface electrocardio activity information under the limited number of leads; the mature dynamic electrocardiogram acquisition box is adopted, the synchronous acquisition purpose is achieved in a parallel connection mode, the method is innovative, and more channels can be further expanded according to clinical requirements; can be used for analyzing various clinically common arrhythmia (such as ventricular premature beat origin point positioning), myocardial infarction (such as acute myocardial infarction part judgment), cardiomyopathy (such as hypertrophic cardiomyopathy and the like) and the like, and has higher clinical transformation prospect and clinical diagnosis application value.

Description

一种多通道体表心电信号同步实时采集系统A multi-channel body surface ECG signal synchronous real-time acquisition system

技术领域technical field

本发明属于心电信号采集分析技术及设备领域,尤其涉及一种多通道体表心电信号同步实时采集系统。The invention belongs to the field of electrocardiographic signal acquisition and analysis technology and equipment, and in particular relates to a multi-channel body surface electrocardiographic signal synchronous real-time acquisition system.

背景技术Background technique

常规12导联体表心电图是传统的临床判断手段,用于分析和诊断心律失常已逾100年,如用于定位室性早搏起源、房性早搏起源位置等。但常规12导联心电图存在其固有缺陷,如导联放置位置不标准、因心脏转位、胸腔解剖及患者个体异质性所导致的图形不精确性,标测精确度不高等,同时因其只有有限的导联数目,导致常规12导联心电图诊断心律失常等准确性不高,并且不同判断者之间异质性较大,特别是对于一些反映在人体背面的体表信息无法及时捕捉,如急性后壁、下壁心肌梗死时背部体表心电图的特异性变化等。因此如何利用有限的体表心电导联数量来更加准确、全面、有效反映并记录体表心电信号一直是心电学研究及应用的热点。Conventional 12-lead body surface electrocardiogram is a traditional clinical judgment method, which has been used for analyzing and diagnosing arrhythmia for more than 100 years, such as locating the origin of ventricular premature beats and atrial premature beats. However, the conventional 12-lead ECG has its inherent defects, such as non-standard lead placement, inaccurate graphics due to heart transposition, thoracic anatomy, and individual patient heterogeneity, and low mapping accuracy. There is only a limited number of leads, resulting in low accuracy of conventional 12-lead ECG in diagnosing arrhythmia, and the heterogeneity among different judges is large, especially for some body surface information reflected on the back of the human body that cannot be captured in time. Such as the specific changes of the back body surface ECG in acute posterior wall and inferior wall myocardial infarction. Therefore, how to use the limited number of body surface ECG leads to more accurately, comprehensively and effectively reflect and record body surface ECG signals has always been a hot spot in the research and application of electrocardiology.

因此19世纪初,在常规12导联体表心电图基础上的体表电位标测技术应运而生。该技术显著延伸了标准12导联心电图的应用范围,其采用较多体表电极、体表分布范围广、分析相对精细,故可较常规心电图获得更多、更细微、更全面的心脏电活动变化规律,有较强的科研及临床应用价值。但截止目前市场上并无成熟产品用于同步、实时采集体表多通道、多个导联的心电图信息,用于分析各类心律失常。一些临床研究给出的方案是采用体表柔性电极条带,每个条带包含8-10个电极不等,采用多个电极条带的方式采集多通道体表心电信息,但是上述方案存在缺陷,如该设备为科研用途,条带上的每个电极块对于体表微弱心电信号的采集并未经实际临床验证,对于条带上电极块与人体的有效接触、心电信号的有效准确提取、较大噪声及杂波干扰的处理等问题仍未获得圆满方案,同时采用固定的电极条带长度及结构,对于不同个体不同的体表结构,不能有效达到每个采集点的精确定位采集。而另一些研究采用的是背心式方案,通过背心中设置多个电极块用以采集多通道体表心电信号,也存在上述的电极接触及采集的准确性、不同个体采集时的采集点差异性等问题。同时上述方案采集体表心电图时并非采用公认有效的基于Wilson心电图导联体系的采集方案,因此采集获得信号的精确性、有效性及临床应用价值受限。Therefore, in the early 19th century, the body surface potential mapping technology based on the conventional 12-lead body surface electrocardiogram came into being. This technology significantly extends the application range of the standard 12-lead ECG. It uses more body surface electrodes, a wide range of body surface distribution, and relatively fine analysis, so it can obtain more, more subtle, and more comprehensive cardiac electrical activities than conventional ECGs. The change rule has strong scientific research and clinical application value. But so far, there is no mature product on the market for synchronous and real-time collection of multi-channel and multi-lead ECG information on the body surface for analysis of various arrhythmias. Some clinical studies have proposed the use of flexible electrode strips on the body surface, each strip contains 8-10 electrodes, and multiple electrode strips are used to collect multi-channel body surface ECG information, but the above-mentioned schemes exist Defects, if the equipment is used for scientific research, each electrode block on the strip has not been clinically verified for the collection of weak ECG signals on the body surface, and the effective contact between the electrode blocks on the strip and the human body and the effective Problems such as accurate extraction, large noise and clutter interference processing have not yet been satisfactorily solved. At the same time, the use of fixed electrode strip length and structure cannot effectively achieve accurate positioning of each collection point for different body surface structures of different individuals. collection. However, some other studies have adopted a vest-type scheme. Multiple electrode blocks are set in the vest to collect multi-channel body surface ECG signals. There are also differences in the above-mentioned electrode contact and collection accuracy, and the collection points of different individuals. issues such as sex. At the same time, the above scheme does not adopt the recognized and effective acquisition scheme based on the Wilson ECG lead system when collecting body surface ECG, so the accuracy, effectiveness and clinical application value of the acquired signal are limited.

发明内容Contents of the invention

本发明的目的在于针对现有技术的不足,提供一种多通道体表心电信号同步实时采集系统。The object of the present invention is to provide a multi-channel body surface electrocardiographic signal synchronous real-time acquisition system for the deficiencies of the prior art.

本发明的目的是通过以下技术方案来实现的:一种多通道体表心电信号同步实时采集系统,该系统包括64导联体表心电图采集集成盒、心电导联贴片;所述心电导联贴片连接由8个10通道动态心电记录盒并联组成的64导联体表心电图采集集成盒,同步实时采集64通道体表心电图。The purpose of the present invention is achieved through the following technical solutions: a multi-channel body surface electrocardiogram synchronous real-time acquisition system, which includes a 64-lead body surface electrocardiogram collection integrated box and an electrocardiogram lead patch; The connected patch is connected to the 64-lead body surface ECG collection integrated box composed of eight 10-channel dynamic ECG recording boxes in parallel, and the 64-channel body surface ECG is collected synchronously and in real time.

进一步地,所述同步实时采集64通道体表心电图具体为:将8个10通道动态心电图采集盒,分别标记为1-8号动态采集盒;每个动态采集盒采集10通道体表心电数据,将其中2个通道标记为RA和RL参考导联,分别固定于右上肢远端及右下肢近端,剩余8个通道标记为8个导联用于采集体表心电图;其中,1号动态采集盒参考导联通道为RA1和RL1,体表心电图采集导联标记为L1-L8,分别固定于标号1-8位置;2号动态采集盒参考导联通道为RA2和RL2,体表心电图采集导联标记为L9-L16,分别固定于标号9-16位置;3号动态采集盒参考导联通道为RA3和RL3,体表心电图采集导联标记为L17-L24,分别固定于标号17-24位置;4号动态采集盒参考导联通道为RA4和RL4,体表心电图采集导联标记为L25-L32,分别固定于标号25-32位置;5号动态采集盒参考导联通道为RA5和RL5,体表心电图采集导联标记为L33-L40,分别固定于标号33-40位置;6号动态采集盒参考导联通道为RA6和RL6,体表心电图采集导联标记为L41-L48,分别固定于标号41-48位置;7号动态采集盒参考导联通道为RA7和RL7,体表心电图采集导联标记为L49-L56,分别固定于标号49-56位置;8号动态采集盒参考导联通道为RA8和RL8,体表心电图采集导联标记为L57-L64,分别固定于标号57-60位置。Further, the synchronous real-time acquisition of 64-channel body surface electrocardiogram is specifically: mark eight 10-channel dynamic electrocardiogram acquisition boxes as No. 1-8 dynamic acquisition boxes respectively; each dynamic acquisition box collects 10-channel body surface electrocardiogram data , 2 of the channels are marked as RA and RL reference leads, which are respectively fixed at the distal end of the right upper limb and the proximal end of the right lower limb, and the remaining 8 channels are marked as 8 leads for collecting body surface ECG; among them, No. 1 dynamic The reference lead channels of the acquisition box are RA1 and RL1, and the acquisition leads of the body surface ECG are marked L1-L8, which are respectively fixed at the positions marked 1-8; the reference lead channels of the No. 2 dynamic acquisition box are RA2 and RL2, and the acquisition The lead marks are L9-L16, which are respectively fixed at the positions marked 9-16; the reference lead channels of No. 3 dynamic acquisition box are RA3 and RL3, and the leads for body surface ECG acquisition are marked L17-L24, which are respectively fixed at the marks 17-24 Position; the reference lead channels of the No. 4 dynamic acquisition box are RA4 and RL4, and the surface ECG acquisition leads are marked as L25-L32, which are respectively fixed at the positions marked 25-32; the reference lead channels of the No. 5 dynamic acquisition box are RA5 and RL5 , the body surface ECG acquisition leads are marked as L33-L40, which are respectively fixed at positions marked 33-40; the No. 6 dynamic acquisition box reference lead channels are RA6 and RL6, and the body surface ECG acquisition leads are marked as L41-L48, which are respectively fixed At the positions marked 41-48; the reference lead channels of the No. 7 dynamic acquisition box are RA7 and RL7, and the acquisition leads of the body surface ECG are marked L49-L56, which are respectively fixed at the positions marked 49-56; the reference lead channels of the No. 8 dynamic acquisition box are connected The tracks are RA8 and RL8, and the surface electrocardiogram acquisition leads are marked L57-L64, which are respectively fixed at positions marked 57-60.

进一步地,所述标号1-49分布于体表前胸部,标号50-64分布于体表后背部;所述标号1-64在体表前胸部分布的上界平胸骨上窝,下界位于脐水平线,共分为7行11列;其中,标号1-3沿右侧腋中线分布;标号4-6以及7-9分别分布在右侧锁骨中线两侧,其中标号4-6所在列处于右锁骨中线与右腋前线中间平行线位置,标号7-9处于右锁骨中线与右胸骨旁线中间平行线位置;标号10-16以及17-23分别沿右、左两侧胸骨旁线分布,标号38-41沿左锁骨中线分布,标号24-29、标号30-31、标号32-37所在列依次分布于左胸骨旁线及左锁骨中线之间且间隔相等,标号42-45沿左侧腋前线分布,标号46-49沿左侧腋中线分布;所述标号1-64在体表后背部分布的上界平对第4胸椎体,下界平第10胸椎高度,共3行5列;其中标号50-52沿左侧腋后线分布,标号53-55以及62-64分别沿左、右两侧肩胛下线分布,标号56-58以及59-61分别沿左、右两侧脊柱旁线分布;其中,标号10、17位于同一水平面,为第1层;标号4、7、11、18、24、32、50、53、56、59、62分布在同一水平面,为第2层;标号12、19、25、33、38位于同一水平面,为第3层;标号1、5、8、13、20、26、30、34、39、42、46、51、54、57、60和63分布在同一水平面,为第4层,位于第4肋间隙水平;标号2、14、21、27、31、35、40、43、47位于同一水平面,为第5层;标号3、6、9、15、22、28、36、41、44、48、52、55、58、61、64分布在同一水平面,为第6层;标号16、23、29、37、45、49位于同一水平面,为第7层;其中,第1-3层标号水平面位于第4肋间隙水平之上,间隔3cm平均分布;第5-7层标号水平面位于第4肋间隙水平之下,间隔3cm平均分布。Further, the numbers 1-49 are distributed on the front chest of the body surface, and the numbers 50-64 are distributed on the back of the body surface; the upper boundary of the number 1-64 distributed on the front chest of the body surface is the flat suprasternal fossa, and the lower boundary is located at the umbilicus The horizontal lines are divided into 7 rows and 11 columns; among them, the labels 1-3 are distributed along the right midaxillary line; the labels 4-6 and 7-9 are respectively distributed on both sides of the right midclavicular line, and the columns where the labels 4-6 are located are in the right The position of the middle parallel line between the midclavicular line and the right anterior axillary line, and the markings 7-9 are at the position parallel to the middle line between the right midclavicular line and the right parasternal line; the markings 10-16 and 17-23 are distributed along the right and left parasternal lines respectively, and the markings are 38-41 are distributed along the left midclavicular line, and the rows of numbers 24-29, 30-31, and 32-37 are distributed between the left parasternal line and the left midclavicular line in sequence with equal intervals, and the numbers 42-45 are along the left axilla Distributed on the front line, the marks 46-49 are distributed along the left midaxillary line; the upper boundary of the distribution of the above marks 1-64 on the back of the body surface is level with the 4th thoracic vertebra, and the lower boundary is equal to the height of the 10th thoracic vertebra, with 3 rows and 5 columns in total; The marks 50-52 are distributed along the left posterior axillary line, the marks 53-55 and 62-64 are distributed along the subscapular lines of the left and right sides respectively, and the marks 56-58 and 59-61 are distributed along the left and right sides of the spine respectively line distribution; among them, labels 10 and 17 are located on the same horizontal plane, which is the first floor; labels 4, 7, 11, 18, 24, 32, 50, 53, 56, 59, and 62 are distributed on the same horizontal plane, which is the second floor; Numbers 12, 19, 25, 33, and 38 are located on the same horizontal plane, which is the third floor; Numbers 1, 5, 8, 13, 20, 26, 30, 34, 39, 42, 46, 51, 54, 57, 60 and 63 are distributed on the same horizontal plane, which is the 4th floor, located at the level of the 4th intercostal space; numbers 2, 14, 21, 27, 31, 35, 40, 43, 47 are located on the same horizontal plane, which is the 5th floor; numbers 3, 6, 9, 15, 22, 28, 36, 41, 44, 48, 52, 55, 58, 61, and 64 are distributed on the same level, which is the sixth floor; labels 16, 23, 29, 37, 45, and 49 are located on the same level , is the 7th layer; among them, the marked levels of the 1st to 3rd layers are located above the level of the 4th intercostal space, and are evenly distributed at intervals of 3 cm; the marked levels of the 5th to 7th layers are located below the level of the 4th intercostal space, and are evenly distributed at an interval of 3 cm.

进一步地,所述64导联体表心电图采集集成盒以RA1-RA8和对应的RL1-RL8产生的Wilson中心电端为电压基准,采样频率1000Hz,每2个字节一个通道,15位A/D转换,基线为2^14,幅值范围为±5mv。Further, the 64-lead body surface electrocardiogram acquisition integrated box uses the Wilson central electrical terminal generated by RA1-RA8 and the corresponding RL1-RL8 as the voltage reference, the sampling frequency is 1000Hz, one channel per 2 bytes, 15-bit A/ D conversion, the baseline is 2^14, and the amplitude range is ±5mv.

进一步地,所述心电导联贴片通过全屏蔽电缆及引线连接所述64导联体表心电图采集集成盒。Further, the ECG lead patch is connected to the 64-lead body surface ECG collection integrated box through a fully shielded cable and lead wires.

本发明的有益效果是:The beneficial effects of the present invention are:

1、本发明采用了经过临床数据优化的64个多导联体表电极位置,在有限的导联数目下充分完整地反应体表心电活动信息;1. The present invention adopts 64 multi-lead body surface electrode positions optimized by clinical data, which can fully and completely reflect body surface electrocardiographic activity information under a limited number of leads;

2、本发明采用专用体表心电图贴片及连接导线,相比于既往采用阵列电极、条带电极、心电采集背心等方式,保证心电信号采集的准确性以及心电信号传输的完整性;2. The present invention adopts special body surface electrocardiogram patches and connecting wires, which ensure the accuracy of electrocardiographic signal acquisition and the integrity of electrocardiographic signal transmission compared with the previous methods such as array electrodes, strip electrodes, and electrocardiographic collection vests. ;

3、本发明采用成熟的动态心电图采集盒,通过并联方式达到同步采集目的,方法上创新,并且根据临床需要可进一步扩展64通道至更多的通道;3. The present invention adopts a mature dynamic electrocardiogram acquisition box to achieve the purpose of synchronous acquisition through parallel connection, which is innovative in method, and can further expand 64 channels to more channels according to clinical needs;

4、本发明用于分析临床常见的各类心律失常(如室性早搏起源点定位)、心肌梗死(如急性心肌梗死部位判断)、心肌病(如肥厚型心肌病等诊断)等,有较高的临床转化前景及临床诊断应用价值。4. The present invention is used to analyze clinically common various arrhythmias (such as ventricular premature beat origin point positioning), myocardial infarction (such as acute myocardial infarction site judgment), cardiomyopathy (such as diagnosis of hypertrophic cardiomyopathy), etc. High clinical transformation prospects and clinical diagnostic application value.

附图说明Description of drawings

图1是多通道体表心电图采集盒及采集分析方法示意图;Fig. 1 is a schematic diagram of a multi-channel body surface electrocardiogram collection box and a collection and analysis method;

图2是64导联体表心电贴片定位及放置示意图;Figure 2 is a schematic diagram of the positioning and placement of the 64-lead body surface ECG patch;

图3是体表心电图处理分析软件获得的64导联体表心电图;Fig. 3 is the 64-lead body surface electrocardiogram obtained by body surface electrocardiogram processing and analysis software;

图4是64导联体表心电贴片定位及放置示意图;Fig. 4 is a schematic diagram of positioning and placement of a 64-lead body surface ECG patch;

图5是多通道体表心电图采集盒工作示意图;Fig. 5 is a working schematic diagram of a multi-channel body surface electrocardiogram acquisition box;

图6是一例室性早搏患者的64导联体表心电图。Figure 6 is a 64-lead surface electrocardiogram of a patient with premature ventricular contractions.

具体实施方式detailed description

本发明提供一种64通道体表心电图同步实时采集系统采集64通道体表心电图并传输至分析软件的工作流程如图1所示,主要包括:The present invention provides a 64-channel body surface electrocardiogram synchronous real-time acquisition system to collect 64-channel body surface electrocardiogram and transmit it to the workflow of analysis software as shown in Figure 1, mainly including:

1、基于成熟产品-10通道动态心电记录盒的64导联体表心电图采集集成盒,以及同步采集方案;1. Based on the mature product-10-channel dynamic ECG recording box, the 64-lead body surface ECG collection integrated box, and the synchronous collection scheme;

多通道体表心电图采集盒及同步采集方案:本发明采用8个10通道动态心电图采集盒,分别标记为1-8号动态采集盒(采集盒1#-8#)。每个动态心电图采集盒可采集10通道体表心电数据,我们将其中2个通道标记为RA(right arm)和RL(right leg)导联,将导联分别固定于右上肢远端及右下肢近端,用以提供威尔逊Wilson中心电端,并作为每个动态心电采集盒的电压基准;剩余8个通道标记为8个导联用于采集体表心电图。同时将8个动态采集盒并联,获得能够基于Wilson中心电端作为基准电压并且同步实时采集64通道体表心电图的多通道心电采集盒,将其信号输出模块连接电脑,实时传输采集获得的多通道体表心电信号数据;并进行时钟及基线校准使每个动态采集盒同时开启信号采集。并联设置后,其中,1#采集盒参考导联通道为RA1和RL1,固定于右上肢及右下肢,体表心电图采集导联标记为L1-L8,分别固定于上图2中的标号1-8位置;2#采集盒参考导联通道为RA2和RL2,固定于右上肢及右下肢,体表心电图采集导联标记为L9-L16,分别固定于上图2中的标号9-16位置;3#采集盒参考导联通道为RA3和RL3,固定于右上肢及右下肢,体表心电图采集导联标记为L17-L24,分别固定于上图2中的标号17-24位置;4#采集盒参考导联通道为RA4和RL4,固定于右上肢及右下肢,体表心电图采集导联标记为L25-L32,分别固定于上图2中的标号25-32位置;5#采集盒参考导联通道为RA5和RL5,固定于右上肢及右下肢,体表心电图采集导联标记为L33-L40,分别固定于上图2中的标号33-40位置;6#采集盒参考导联通道为RA6和RL6,固定于右上肢及右下肢,体表心电图采集导联标记为L41-L48,分别固定于上图2中的标号41-48位置;7#采集盒参考导联通道为RA7和RL7,固定于右上肢及右下肢,体表心电图采集导联标记为L49-L56,分别固定于上图2中的标号49-56位置;8#采集盒参考导联通道为RA8和RL8,固定于右上肢及右下肢,体表心电图采集导联标记为L57-L64,分别固定于上图2中的标号57-60位置。并联后的64通道体表心电图采集设备参数如下:以RA1-8以及RL1-8产生的Wilson中心电端为电压基准,采样频率1000Hz,每2个字节一个通道,15位A/D转换,基线为2^14,幅值范围±5mv。Multi-channel body surface electrocardiogram acquisition box and synchronous acquisition scheme: the present invention adopts eight 10-channel dynamic electrocardiogram acquisition boxes, which are respectively marked as No. 1-8 dynamic acquisition boxes (collection boxes 1#-8#). Each dynamic electrocardiogram collection box can collect 10 channels of body surface ECG data. We label 2 of the channels as RA (right arm) and RL (right leg) leads, and fix the leads to the distal end of the right upper limb and the right arm respectively. The proximal end of the lower extremity is used to provide the Wilson central electrical terminal and serves as the voltage reference of each dynamic ECG collection box; the remaining 8 channels are marked as 8 leads for collecting body surface ECG. At the same time, 8 dynamic acquisition boxes are connected in parallel to obtain a multi-channel ECG acquisition box that can collect 64-channel body surface ECG in real time based on the Wilson central electrical terminal as a reference voltage. Connect its signal output module to a computer to transmit and acquire multiple data in real time channel body surface ECG signal data; and perform clock and baseline calibration so that each dynamic acquisition box starts signal acquisition at the same time. After setting in parallel, the reference lead channels of the 1# acquisition box are RA1 and RL1, which are fixed on the right upper and lower limbs, and the surface ECG acquisition leads are marked as L1-L8, which are respectively fixed on the labels 1- 8 positions; the reference lead channels of the 2# acquisition box are RA2 and RL2, which are fixed on the right upper and lower limbs, and the surface ECG acquisition leads are marked as L9-L16, which are respectively fixed at positions 9-16 in Figure 2 above; The reference lead channels of the 3# collection box are RA3 and RL3, which are fixed on the right upper and lower limbs. The reference lead channels of the box are RA4 and RL4, which are fixed on the right upper and lower limbs, and the surface ECG acquisition leads are marked as L25-L32, which are respectively fixed at the positions marked 25-32 in Figure 2 above; 5# collection box reference lead The connecting channels are RA5 and RL5, which are fixed on the right upper and lower limbs, and the surface ECG acquisition leads are marked as L33-L40, which are respectively fixed at the positions marked 33-40 in Figure 2 above; the reference lead channel of the 6# collection box is RA6 and RL6 are fixed on the right upper and lower limbs, and the surface ECG acquisition leads are marked L41-L48, which are respectively fixed at the positions marked 41-48 in Figure 2 above; the reference lead channels of the 7# acquisition box are RA7 and RL7 , fixed on the right upper and lower limbs, the surface ECG acquisition leads are marked L49-L56, which are respectively fixed at the positions marked 49-56 in Figure 2 above; the reference lead channels of the 8# acquisition box are RA8 and RL8, which are fixed on For the right upper limb and right lower limb, the surface electrocardiogram acquisition leads are marked L57-L64, which are respectively fixed at positions marked 57-60 in Figure 2 above. The parameters of the 64-channel body surface ECG acquisition equipment after parallel connection are as follows: the Wilson central electrical terminal generated by RA1-8 and RL1-8 is used as the voltage reference, the sampling frequency is 1000Hz, one channel per 2 bytes, 15-bit A/D conversion, The baseline is 2^14, and the amplitude range is ±5mv.

2、64导联专用心电导联贴片定位及放置方法;2. The positioning and placement method of the 64-lead ECG lead patch;

多通道体表心电导联定位及放置方案:本发明所采用的64导联专用体表心电贴片体表定位及放置方案见下图2。图中每一个黑色点表示一个心电图电极贴片位置,从标号1至标号64;其中,标号1-49分布于体表前胸部,标号50-64分布于体表后背部。64个贴片在体表前胸部分布的上界平胸骨上窝,下界位于脐水平线,共分为7行11列,各列电极数量不等。其中,标号13对应常规12导联心电图的V1位置,标号20对应常规12导联心电图V2位置,标号40对应常规12导联心电图V4位置,标号43对应常规12导联心电图V5位置,标号47对应常规12导联心电图V6位置。标号1-3沿右侧腋中线分布;标号4-6以及7-9分别分布在右侧锁骨中线两侧,其中标号4-6所在列处于右锁骨中线与右腋前线中间平行线位置,标号7-9处于右锁骨中线与右胸骨旁线中间平行线位置;标号10-16以及17-23分别沿右、左两侧胸骨旁线分布,标号38-41沿左锁骨中线分布,标号24-29、标号30-31、标号32-37所在列依次分布于左胸骨旁线及左锁骨中线之间且间隔相等,标号42-45沿左侧腋前线分布,标号46-49沿左侧腋中线分布。64个贴片在体表后背部分布的上界平对第4胸椎体,下界平第10胸椎高度,共3行5列。标号50-52沿左侧腋后线分布,标号53-55以及62-64分别沿左、右两侧肩胛下线分布,标号56-58以及59-61分别沿左、右两侧脊柱旁线分布。标号10、17位于同一水平面,为第1层;标号4、7、11、18、24、32、50、53、56、59、62分布在同一水平面,为第2层;标号12、19、25、33、38位于同一水平面,为第3层;标号1、5、8、13、20、26、30、34、39、42、46、51、54、57、60和63分布在同一水平面,为第4层,位于第4肋间隙水平;标号2、14、21、27、31、35、40、43、47位于同一水平面,为第5层;标号3、6、9、15、22、28、36、41、44、48、52、55、58、61、64分布在同一水平面,为第6层;标号16、23、29、37、45、49位于同一水平面,为第7层;其中,第1-3层标号水平面位于第4肋间隙水平之上,间隔3cm平均分布;第5-7层标号水平面位于第4肋间隙水平之下,间隔3cm平均分布。Multi-channel body surface ECG lead positioning and placement scheme: The body surface positioning and placement scheme of the 64-lead dedicated body surface ECG patch used in the present invention is shown in Figure 2 below. Each black dot in the figure represents the position of an electrocardiogram electrode patch, from number 1 to number 64; among them, numbers 1-49 are distributed on the front chest of the body surface, and numbers 50-64 are distributed on the back of the body surface. The 64 patches are distributed on the body surface in the anterior chest, the upper border is flat to the suprasternal fossa, and the lower border is located at the level of the umbilicus. They are divided into 7 rows and 11 columns, and the number of electrodes in each column varies. Among them, the label 13 corresponds to the V1 position of the conventional 12-lead ECG, the label 20 corresponds to the V2 position of the conventional 12-lead ECG, the label 40 corresponds to the V4 position of the conventional 12-lead ECG, the label 43 corresponds to the V5 position of the conventional 12-lead ECG, and the label 47 corresponds to Conventional 12-lead ECG V6 position. Labels 1-3 are distributed along the right midaxillary line; labels 4-6 and 7-9 are distributed on both sides of the right midclavicular line respectively, and the column of labels 4-6 is located in the middle parallel line between the right midclavicular line and the right anterior axillary line. 7-9 are located in the middle parallel line between the right midclavicular line and right parasternal line; labels 10-16 and 17-23 are distributed along the right and left parasternal lines respectively; labels 38-41 are distributed along the left midclavicular line; labels 24- 29. The columns of labels 30-31 and 32-37 are distributed between the left parasternal line and the left midclavicular line in sequence with equal intervals, labels 42-45 are distributed along the left anterior axillary line, and labels 46-49 are distributed along the left midaxillary line distributed. The upper boundary of the 64 patches distributed on the back of the body surface is equal to the 4th thoracic vertebra, and the lower boundary is equal to the height of the 10th thoracic vertebra, with a total of 3 rows and 5 columns. Labels 50-52 are distributed along the left posterior axillary line, labels 53-55 and 62-64 are distributed along the left and right subscapular lines respectively, and labels 56-58 and 59-61 are distributed along the left and right paraspinal lines respectively distributed. Labels 10 and 17 are located on the same horizontal plane, which is the first floor; labels 4, 7, 11, 18, 24, 32, 50, 53, 56, 59, and 62 are distributed on the same horizontal plane, which is the second floor; labels 12, 19, 25, 33, 38 are located on the same level, which is the third floor; labels 1, 5, 8, 13, 20, 26, 30, 34, 39, 42, 46, 51, 54, 57, 60 and 63 are distributed on the same level , is the 4th floor, located at the level of the 4th intercostal space; labels 2, 14, 21, 27, 31, 35, 40, 43, 47 are located on the same level, and are the 5th floor; labels 3, 6, 9, 15, 22 , 28, 36, 41, 44, 48, 52, 55, 58, 61, 64 are distributed on the same horizontal plane, which is the 6th floor; labels 16, 23, 29, 37, 45, 49 are located on the same horizontal plane, which is the 7th floor ; Among them, the 1st-3rd layer marked level is above the level of the 4th intercostal space, evenly distributed at an interval of 3cm; the 5th-7th layer marked level is located below the level of the 4th intercostal space, evenly distributed at an interval of 3cm.

所述常规12导联心电图的导联位置V1~V6为:V1:胸骨右缘第四肋间;V2:胸骨左缘第四肋间;V4:左第五肋间与左锁骨中线交汇点;V3:位于V2与V4连线中点;V5:左第五肋间与腋前线交汇处;V6:左第五肋间与腋中线交汇处。The lead positions V1-V6 of the conventional 12-lead electrocardiogram are: V1: the fourth intercostal space on the right border of the sternum; V2: the fourth intercostal space on the left border of the sternum; V4: the intersection point of the left fifth intercostal space and the midline of the left clavicle; V3: at the midpoint of the line connecting V2 and V4; V5: at the junction of the left fifth intercostal space and the anterior axillary line; V6: at the junction of the left fifth intercostal space and the midaxillary line.

3、体表心电图数据处理分析软件。3. Body surface electrocardiogram data processing and analysis software.

采用体表心电图数据处理分析软件,实时采集、保存及导出64导联体表心电图信息(图3),分析各类心律失常等临床应用场景。64通道心电采集集成盒子中的L1-L64导联所在位置采集获得的心电图同时涵盖了常规12导联体表心电图信息,如L13对应常规12导联心电图的V1,L20对应常规12导联心电图V2,L40对应常规12导联心电图V4,L43对应常规12导联心电图V5,L47对应常规12导联心电图V6。The body surface electrocardiogram data processing and analysis software is used to collect, save and export 64-lead body surface electrocardiogram information in real time (Figure 3), and analyze various clinical application scenarios such as arrhythmia. The ECG collected at the location of the L1-L64 leads in the 64-channel ECG collection integrated box also covers the conventional 12-lead body surface ECG information, for example, L13 corresponds to V1 of the conventional 12-lead ECG, and L20 corresponds to the conventional 12-lead ECG V2 and L40 correspond to the conventional 12-lead ECG V4, L43 corresponds to the conventional 12-lead ECG V5, and L47 corresponds to the conventional 12-lead ECG V6.

实施例Example

步骤1:清理被采集者胸前及背部采集区域皮肤,并按照本发明提供的心电图导联定位方案固定64个专用体表心电图贴片(一次性使用心电电极,型号LT-301,上海励图医疗器材有限公司,中国上海)(图4);Step 1: Clean up the skin of the collected area on the chest and back of the collected person, and fix 64 special body surface ECG patches (disposable ECG electrodes, model LT-301, Shanghai Li Figure Medical Equipment Co., Ltd., Shanghai, China) (Figure 4);

步骤2:将各个专用体表心电图贴片经专用心电图机导联线分别连接至多通道心电采集盒的L1-L64位置,同时将RA1-8连接至右上肢远端,RL1-8连接至右下肢近端(图4);Step 2: Connect each dedicated body surface ECG patch to the L1-L64 position of the multi-channel ECG collection box through the dedicated ECG lead wire, and at the same time connect RA1-8 to the distal end of the right upper limb, and RL1-8 to the right Proximal lower extremity (Figure 4);

所述专用心电图机导联线采用全屏蔽电缆及引线,有较强抗干扰能力,保证心电信号的精确性以及心电信号数据完成性。The dedicated electrocardiograph lead wire adopts fully shielded cables and lead wires, which has a strong anti-interference ability and ensures the accuracy of the electrocardiographic signal and the completeness of the electrocardiographic signal data.

步骤3:开启8个动态心电采集盒,并将心电信号输出导线连接至电脑主机(图5);Step 3: Turn on the 8 dynamic ECG collection boxes, and connect the ECG signal output wires to the host computer (Figure 5);

步骤4:打开体表心电图处理分析软件进行同步采集,获得实时的、同步的64通道体表心电图并分析各类心律失常,如室性早搏等起源等,同时完成采集获得心电图的储存、数据导出等,如图6所示,基于该64导联体表心电图可初步判断该例患者的室性早搏起源灶位于心脏右心室流出道位置。Step 4: Open the body surface ECG processing and analysis software for synchronous acquisition, obtain real-time, synchronous 64-channel body surface ECG and analyze various arrhythmias, such as the origin of ventricular premature beats, etc., and complete the storage and data export of the acquired ECG at the same time etc., as shown in Figure 6, based on the 64-lead body surface electrocardiogram, it can be preliminarily judged that the origin of ventricular premature beats in this patient is located in the right ventricular outflow tract of the heart.

Claims (1)

1.一种多通道体表心电信号同步实时采集系统,其特征在于,该系统包括64导联体表心电图采集集成盒、心电导联贴片;所述心电导联贴片连接由8个10通道动态心电记录盒并联组成的64导联体表心电图采集集成盒,同步实时采集64通道体表心电图;1. a multi-channel body surface electrocardiogram synchronous real-time acquisition system is characterized in that the system includes a 64-lead body surface electrocardiogram acquisition integration box and an electrocardiographic lead patch; the electrocardiographic lead patch is connected by 8 The 64-lead body surface ECG acquisition integrated box composed of 10-channel dynamic ECG recording boxes in parallel can collect 64-channel body surface ECG in real time simultaneously; 所述同步实时采集64通道体表心电图具体为:将8个10通道动态心电图采集盒,分别标记为1-8号动态采集盒;每个动态采集盒采集10通道体表心电数据,将其中2个通道标记为RA和RL参考导联,分别固定于右上肢远端及右下肢近端,剩余8个通道标记为8个导联用于采集体表心电图;其中,1号动态采集盒参考导联通道为RA1和RL1,体表心电图采集导联标记为L1-L8,分别固定于标号1-8位置;2号动态采集盒参考导联通道为RA2和RL2,体表心电图采集导联标记为L9-L16,分别固定于标号9-16位置;3号动态采集盒参考导联通道为RA3和RL3,体表心电图采集导联标记为L17-L24,分别固定于标号17-24位置;4号动态采集盒参考导联通道为RA4和RL4,体表心电图采集导联标记为L25-L32,分别固定于标号25-32位置;5号动态采集盒参考导联通道为RA5和RL5,体表心电图采集导联标记为L33-L40,分别固定于标号33-40位置;6号动态采集盒参考导联通道为RA6和RL6,体表心电图采集导联标记为L41-L48,分别固定于标号41-48位置;7号动态采集盒参考导联通道为RA7和RL7,体表心电图采集导联标记为L49-L56,分别固定于标号49-56位置;8号动态采集盒参考导联通道为RA8和RL8,体表心电图采集导联标记为L57-L64,分别固定于标号57-60位置;The synchronous real-time acquisition of 64-channel body surface electrocardiogram is specifically: eight 10-channel dynamic electrocardiogram acquisition boxes are respectively marked as No. 1-8 dynamic acquisition boxes; each dynamic acquisition box collects 10-channel body surface electrocardiogram data, and the The 2 channels are marked as RA and RL reference leads, which are respectively fixed at the distal end of the right upper limb and the proximal end of the right lower limb, and the remaining 8 channels are marked as 8 leads for collecting body surface ECG; among them, the No. The lead channels are RA1 and RL1, and the lead marks of the body surface ECG acquisition are L1-L8, which are respectively fixed at the positions of labels 1-8; the reference lead channels of No. 2 dynamic acquisition box are RA2 and RL2, and the lead marks of the body surface ECG acquisition are They are L9-L16, which are respectively fixed at positions numbered 9-16; the reference lead channels of No. 3 dynamic acquisition box are RA3 and RL3, and the surface ECG acquisition leads are marked L17-L24, which are respectively fixed at positions marked 17-24; 4 The reference lead channels of the No. 5 dynamic acquisition box are RA4 and RL4, and the body surface ECG acquisition leads are marked as L25-L32, which are respectively fixed at the positions marked 25-32; the reference lead channels of the No. 5 dynamic acquisition box are RA5 and RL5, and the body surface The electrocardiogram acquisition leads are marked as L33-L40, which are respectively fixed at the positions marked 33-40; the reference lead channels of No. -48 position; No. 7 dynamic acquisition box reference lead channels are RA7 and RL7, body surface ECG acquisition leads are marked as L49-L56, which are respectively fixed at positions marked 49-56; No. 8 dynamic acquisition box reference lead channel is RA8 and RL8, the body surface ECG acquisition leads are marked as L57-L64, which are respectively fixed at positions marked 57-60; 所述标号1-49分布于体表前胸部,标号50-64分布于体表后背部;所述标号1-64在体表前胸部分布的上界平胸骨上窝,下界位于脐水平线,共分为7行11列;其中,标号1-3沿右侧腋中线分布;标号4-6以及7-9分别分布在右侧锁骨中线两侧,其中标号4-6所在列处于右锁骨中线与右腋前线中间平行线位置,标号7-9处于右锁骨中线与右胸骨旁线中间平行线位置;标号10-16以及17-23分别沿右、左两侧胸骨旁线分布,标号38-41沿左锁骨中线分布,标号24-29、标号30-31、标号32-37所在列依次分布于左胸骨旁线及左锁骨中线之间且间隔相等,标号42-45沿左侧腋前线分布,标号46-49沿左侧腋中线分布;所述标号1-64在体表后背部分布的上界平对第4胸椎体,下界平第10胸椎高度,共3行5列;其中标号50-52沿左侧腋后线分布,标号53-55以及62-64分别沿左、右两侧肩胛下线分布,标号56-58以及59-61分别沿左、右两侧脊柱旁线分布;其中,标号10、17位于同一水平面,为第1层;标号4、7、11、18、24、32、50、53、56、59、62分布在同一水平面,为第2层;标号12、19、25、33、38位于同一水平面,为第3层;标号1、5、8、13、20、26、30、34、39、42、46、51、54、57、60和63分布在同一水平面,为第4层,位于第4肋间隙水平;标号2、14、21、27、31、35、40、43、47位于同一水平面,为第5层;标号3、6、9、15、22、28、36、41、44、48、52、55、58、61、64分布在同一水平面,为第6层;标号16、23、29、37、45、49位于同一水平面,为第7层;其中,第1-3层标号水平面位于第4肋间隙水平之上,间隔3cm平均分布;第5-7层标号水平面位于第4肋间隙水平之下,间隔3cm平均分布;The labels 1-49 are distributed on the front chest of the body surface, and the labels 50-64 are distributed on the back of the body surface; the upper boundary of the labels 1-64 distributed on the front chest of the body surface is the flat suprasternal fossa, and the lower boundary is located at the umbilical level line. It is divided into 7 rows and 11 columns; among them, the labels 1-3 are distributed along the right midaxillary line; the labels 4-6 and 7-9 are respectively distributed on both sides of the right midclavicular line, and the columns of the labels 4-6 are located between the right midclavian line and The position of the middle parallel line of the right anterior axillary line, markings 7-9 are located at the middle parallel line of the right midclavicular line and right parasternal line; markings 10-16 and 17-23 are distributed along the right and left parasternal lines respectively, markings 38-41 Distributed along the left midclavicular line, the columns where the labels 24-29, 30-31, and 32-37 are located are distributed in turn between the left parasternal line and the left midclavicular line with equal intervals, and the labels 42-45 are distributed along the left anterior axillary line, Labels 46-49 are distributed along the left midaxillary line; the upper boundary of the distribution of the labels 1-64 on the back of the body surface is equal to the 4th thoracic vertebra, and the lower boundary is equal to the height of the 10th thoracic vertebra, with a total of 3 rows and 5 columns; of which the label 50 -52 is distributed along the left posterior axillary line, markings 53-55 and 62-64 are distributed along the left and right subscapular lines respectively, and markings 56-58 and 59-61 are distributed along the left and right paraspinal lines respectively; Among them, labels 10 and 17 are located on the same horizontal plane, which is the first floor; labels 4, 7, 11, 18, 24, 32, 50, 53, 56, 59, and 62 are distributed on the same horizontal plane, which is the second floor; labels 12, 19, 25, 33, 38 are located on the same level, which is the third floor; labels 1, 5, 8, 13, 20, 26, 30, 34, 39, 42, 46, 51, 54, 57, 60 and 63 are distributed in The same horizontal plane is the 4th floor, which is located at the level of the 4th intercostal space; the numbers 2, 14, 21, 27, 31, 35, 40, 43, 47 are located on the same horizontal plane, which is the 5th floor; the numbers 3, 6, 9, 15 , 22, 28, 36, 41, 44, 48, 52, 55, 58, 61, 64 are distributed on the same horizontal plane, which is the 6th floor; labels 16, 23, 29, 37, 45, 49 are located on the same horizontal plane, which is the 6th floor 7 layers; among them, the 1st-3rd layer marked level is above the level of the 4th intercostal space, evenly distributed at an interval of 3cm; the 5th-7th layer marked level is located below the level of the 4th intercostal space, evenly distributed at an interval of 3cm; 所述64导联体表心电图采集集成盒以RA1-RA8和对应的RL1-RL8产生的Wilson中心电端为电压基准,采样频率1000Hz,每2个字节一个通道,15位A/D转换,基线为2^14,幅值范围为
Figure DEST_PATH_IMAGE002
5mv;
The 64-lead body surface electrocardiogram acquisition integration box uses the Wilson central electrical terminal generated by RA1-RA8 and the corresponding RL1-RL8 as the voltage reference, the sampling frequency is 1000Hz, one channel per 2 bytes, 15-bit A/D conversion, The baseline is 2^14, and the amplitude range is
Figure DEST_PATH_IMAGE002
5mv;
所述心电导联贴片通过全屏蔽电缆及引线连接所述64导联体表心电图采集集成盒。The ECG lead patch is connected to the 64-lead body surface ECG collection integrated box through a fully shielded cable and lead wires.
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