CN110806489B - Anti-interference dry chemical combination detection device - Google Patents
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- 238000001514 detection method Methods 0.000 title claims abstract description 117
- 239000000126 substance Substances 0.000 title claims abstract description 21
- 239000008280 blood Substances 0.000 claims abstract description 31
- 210000004369 blood Anatomy 0.000 claims abstract description 30
- 238000000926 separation method Methods 0.000 claims abstract description 22
- 102100036475 Alanine aminotransferase 1 Human genes 0.000 claims description 22
- 108010082126 Alanine transaminase Proteins 0.000 claims description 22
- 102000001554 Hemoglobins Human genes 0.000 claims description 19
- 108010054147 Hemoglobins Proteins 0.000 claims description 19
- 239000000463 material Substances 0.000 claims description 10
- 239000012528 membrane Substances 0.000 claims description 10
- 238000009941 weaving Methods 0.000 claims description 9
- 238000001914 filtration Methods 0.000 claims description 7
- 229920000728 polyester Polymers 0.000 claims description 7
- 239000004677 Nylon Substances 0.000 claims description 6
- 229920001778 nylon Polymers 0.000 claims description 6
- 239000004744 fabric Substances 0.000 claims description 5
- 230000017531 blood circulation Effects 0.000 abstract description 3
- 238000012864 cross contamination Methods 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 239000003153 chemical reaction reagent Substances 0.000 description 10
- 238000012360 testing method Methods 0.000 description 8
- 210000002966 serum Anatomy 0.000 description 6
- 206010018910 Haemolysis Diseases 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 230000008588 hemolysis Effects 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 2
- 230000002949 hemolytic effect Effects 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 229920000742 Cotton Polymers 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- 239000004695 Polyether sulfone Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000007705 chemical test Methods 0.000 description 1
- 239000000084 colloidal system Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 238000010030 laminating Methods 0.000 description 1
- 238000007449 liver function test Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 229920006393 polyether sulfone Polymers 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 238000009666 routine test Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
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- G—PHYSICS
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/726—Devices
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/91188—Transferases (2.) transferring nitrogenous groups (2.6)
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Abstract
The invention discloses an anti-interference dry chemical combination detection device which comprises a base, a sample adding cover, a flow dividing layer, a separation block, a first detection channel and a second detection channel, wherein the middle part of one side of the base is provided with the separation block, the two sides of the separation block are respectively provided with the first detection channel and the second detection channel, the first detection channel is internally provided with a first non-return layer, the second detection channel is internally provided with a second non-return layer, the flow dividing layer and the sample adding cover are sequentially arranged above the separation block, the flow dividing layer covers the first detection channel and the second detection channel, and the sample adding cover is provided with a sample adding hole. The anti-interference dry chemical combination detection device has a simple structure, is easy to manufacture, can effectively ensure that blood flows from the sample adding hole to the first detection channel and the second detection channel respectively by arranging the flow dividing layer, the first non-return layer and the second non-return layer, does not cause cross contamination or mutual interference caused by backflow, and can facilitate one-time blood adding and two-function detection simultaneously.
Description
Technical Field
The invention relates to an anti-interference dry chemical combination detection device.
Background
In clinical test analysis, hemoglobin and glutamic pyruvic transaminase are important physical examination items, especially student physical examination, which are indispensable examination items. However, two items of hemoglobin and glutamic-pyruvic transaminase respectively belong to different test categories, hemoglobin is a blood routine test item, a blood analyzer and a matched solution are generally used for quantitatively detecting a whole blood sample, and glutamic-pyruvic transaminase is a liver function test item, belongs to a serum biochemical item, and a full-automatic biochemical analyzer and a matched ALT kit are generally used for quantitatively detecting the serum sample. When a sample is collected, blood needs to be collected and processed by using different blood collection tubes respectively, and detection of two projects can be completed by using different analysis systems respectively. The operation is relatively complicated.
The application of the dry chemical method can greatly facilitate the detection work, a plurality of serum biochemical projects can be directly detected by using a whole blood sample, and a plurality of combined detection test papers are marketed. In the market, a dry chemical quantitative analysis instrument for respectively carrying out hemoglobin or glutamic pyruvic transaminase and different detection test papers aiming at a single item can be seen, even if the so-called combined detection test paper for hemoglobin and glutamic pyruvic transaminase exists, the hemoglobin test paper and the glutamic pyruvic transaminase test paper are simply arranged and are relatively independent from each other, each detection item needs to be added with a blood sample separately, and the convenient combined rapid detection product for 'one-drop one-step detection' in the true sense is not realized.
However, the dry chemical test paper product for realizing the quantitative detection of two items of hemoglobin and glutamic pyruvic transaminase simultaneously by one drop of blood and one sample addition has not been reported. The reason is that the haemoglobin detection needs the participation of a haemolytic reagent, and the haemolytic reagent can cause serious interference to a detection system for detecting the content of glutamic-pyruvic transaminase in serum (sample haemolysis can cause interference to the detection of serum glutamic-pyruvic transaminase), so that the detection units of haemoglobin and glutamic-pyruvic transaminase are integrated together and the synchronous quantitative detection of one-drop-of-blood and one-sample-feeding is realized, which has become a world problem in the field of detection.
Therefore, a new dry chemical combination detection device for anti-interference hemoglobin and glutamic pyruvic transaminase is needed to solve the above problems.
Disclosure of Invention
The invention aims to provide an anti-interference dry chemical combination detection device, which is used for solving the problem that one drop of blood can only be added into a sample at one time and only one item can be quantitatively detected in the background technology.
In order to achieve the above purpose, the present invention provides the following technical solutions:
the dry chemical combination detection device comprises a base, a sample adding cover, a flow dividing layer, a separation block, a first detection channel and a second detection channel, wherein the middle part of one side of the base is provided with the separation block, the two sides of the separation block are respectively provided with the first detection channel and the second detection channel, the first detection channel is internally provided with a first non-return layer, the second detection channel is internally provided with a second non-return layer, the flow dividing layer and the sample adding cover are sequentially arranged above the separation block, the flow dividing layer covers the first detection channel and the second detection channel, and the sample adding cover is provided with a sample adding hole;
the shunt layer is formed by mutually and perpendicularly intersecting and weaving first thick threads and first thin threads, the first thick threads are warp threads, the first thin threads are weft threads, and the first thick threads cross the first detection channel and the second detection channel;
the first non-return layer is formed by mutually and perpendicularly intersecting and weaving second thick threads and second fine threads, the second thick threads are warp threads, and the second fine threads are weft threads;
the second non-return layer is formed by mutually and perpendicularly intersecting and weaving third thick threads and third fine threads, the third thick threads are warp threads, and the third fine threads are weft threads;
the second thick line and the third thick line are both arranged to cross the first thick line.
Further, the upper surface of the separation pad is higher than the first non-return layer and the second non-return layer.
Still further, still be provided with the hemofilter in the first detection passageway, the hemofilter sets up the below of first non-return layer.
Still further, still be provided with first flow pad in the first detection passageway, the one end setting of first flow pad is in the below of hemofilter membrane, the other end of first flow pad stretches out first detection passageway.
Still further, still include first reaction panel, first reaction panel is located directly over the first flow pad, be provided with first reaction through-hole on the first reaction panel, the below of first reaction through-hole has first reaction membrane.
Still further, still be provided with the sample pad in the second detection passageway, the one end setting of sample pad is in the below of second non-return layer, the other end of sample pad stretches out the second detection passageway.
Still further, still be provided with the second reaction panel in the second detection passageway, the second reaction panel sets up just above the sample pad, be provided with the second reaction through-hole on the second reaction panel, the below of second reaction through-hole has the second reaction membrane.
Still further, be provided with the draw-in groove on the separate piece, the application of sample lid with separate piece's opposite face is provided with the arch, the arch with draw-in groove interference fit.
Further, the flow dividing layer, the first non-return layer and/or the second non-return layer are/is a monofilament mesh.
Further, the second thick line and the third thick line are perpendicular to the first thick line.
Further, the first thick line, the first thin line, the second thick line, the second thin line, the third thick line and the third thin line are all hydrophilic materials.
Still further, the hydrophilic material is polyester or nylon.
Further, the first thick line has a diameter of 2 to 4 times the diameter of the first thin line, the second thick line has a diameter of 2 to 4 times the diameter of the second thin line, and the third thick line has a diameter of 2 to 4 times the diameter of the third thin line.
Further, the first thick threads are all weft threads, and the first fine threads are all warp threads; the second thick threads are all weft threads, and the second fine threads are all warp threads; the third thick lines are all weft lines, and the third fine lines are all warp lines.
The beneficial effects are that: the anti-interference dry chemical combination detection device has a simple structure, is easy to manufacture, can effectively ensure that blood flows from the sample adding hole to the first detection channel and the second detection channel respectively by arranging the flow dividing layer, the first non-return layer and the second non-return layer, does not cause cross contamination or mutual interference caused by backflow, and can facilitate one-time blood adding and two-function detection simultaneously.
Drawings
FIG. 1 is a schematic diagram of a dry chemical combination detection device with anti-interference function according to the present invention;
FIG. 2 is a left side view of the tamper resistant dry chemical combination test device of the present invention;
fig. 3 is a right side view of the anti-interference dry chemical combination detection device of the present invention.
Detailed Description
The following description of the embodiments of the present invention will be made clearly and completely with reference to the accompanying drawings, in which it is apparent that the embodiments described are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Referring to fig. 1-3, the anti-interference dry chemical combination detection device of the invention comprises a base 1, a sample adding cover 2, a flow dividing layer 3, a separation block 4, a first detection channel and a second detection channel, wherein the separation block 4 is arranged in the middle of one side of the base 1, the first detection channel and the second detection channel are respectively arranged on two sides of the separation block 4, a first non-return layer 5 is arranged in the first detection channel, a second non-return layer 6 is arranged in the second detection channel, the flow dividing layer 3 and the sample adding cover 2 are sequentially arranged above the separation block 4, the flow dividing layer 3 covers the first detection channel and the second detection channel, and a sample adding hole 21 is formed in the sample adding cover 2.
The shunt layer 3 is formed by weaving a first thick line and a first thin line in a mutually perpendicular and crossed mode, the first thick line is warp, the first thin line is weft, and the first thick line spans across the first detection channel and the second detection channel.
The first non-return layer 5 is formed by mutually perpendicular cross weaving of second thick threads and second fine threads, the second thick threads are warp threads, and the second fine threads are weft threads.
The second non-return layer 6 is formed by mutually perpendicular and cross weaving of third thick threads and third fine threads, the third thick threads are all warps, and the third fine threads are all wefts.
The second thick line and the third thick line are both arranged to cross the first thick line.
Preferably, the upper surface of the separation block 4 is higher than the first non-return layer 5 and the second non-return layer 6. The blood on the first non-return layer 5 and the second non-return layer 6 can be effectively prevented from flowing back to the shunt layer 3.
Preferably, the first detection channel is further provided with a blood filtering film 51, and the blood filtering film 51 is arranged below the first non-return layer 5. The hemofilter 51 can filter out red blood cells in blood, and is convenient for glutamic-pyruvic transaminase detection.
Preferably, a first flow pad 52 is further disposed in the first detection channel, one end of the first flow pad 52 is disposed below the blood filtering membrane 51, and the other end of the first flow pad 52 extends out of the first detection channel. The blood with red blood cells removed is drained to the glutamic pyruvic transaminase detection reaction panel by the first flow pad 52.
Preferably, the reaction device further comprises a first reaction panel 53, wherein the first reaction panel 53 is positioned right above the first flow pad 52, and the first reaction panel 53 is provided with first reaction through holes.
Preferably, a sample pad 61 is further disposed in the second detection channel, one end of the sample pad 61 is disposed below the second non-return layer 6, and the other end of the sample pad 61 extends out of the second detection channel. The sample pad 61 is used to drain blood to the hemoglobin detection reaction panel.
Preferably, a second reaction panel 62 is further disposed in the second detection channel, the second reaction panel 62 is disposed right above the sample pad 61, and a second reaction through hole is disposed on the second reaction panel 62.
Preferably, the separating block 4 is provided with a clamping groove, the opposite surfaces of the sample adding cover 2 and the separating block 4 are provided with protrusions, and the protrusions are in interference fit with the clamping groove. The interference fit is utilized to realize the matching of the sample adding cover and the separation pad, so that the sample adding device is convenient and quick.
Preferably, the shunt layer 3, the first non-return layer 5 and/or the second non-return layer 6 are a monofilament mesh. The diversion and the countercurrent of blood are conveniently realized.
Preferably, the second thick line and the third thick line are both disposed to perpendicularly intersect the first thick line. The second thick line and the third thick line are perpendicular to the first thick line, so that the blood non-return effect can be realized to the maximum extent on the basis of conveniently realizing split flow.
Preferably, the first thick line, the first thin line, the second thick line, the second thin line, the third thick line and the third thin line are all hydrophilic materials. The hydrophilic material can realize the blood non-return effect to the maximum extent on the basis of conveniently realizing the split flow.
Preferably, the hydrophilic material is polyester or nylon.
Preferably, the first thick line has a diameter of 2 to 4 times the diameter of the first thin line, the second thick line has a diameter of 2 to 4 times the diameter of the second thin line, and the third thick line has a diameter of 2 to 4 times the diameter of the third thin line.
Preferably, the first thick threads are all weft threads, and the first fine threads are all warp threads. The second thick threads are all weft threads, and the second fine threads are all warp threads. The third thick threads are all weft threads, and the third fine threads are all warp threads.
Example 1:
the anti-interference dry chemical combination detection device is used for realizing dry chemical combination detection of hemoglobin and glutamic pyruvic transaminase and comprises a base, an upper cover, a reaction window, a sample adding hole cover and a sample processing unit.
The sample processing unit comprises a flow dividing layer, two independent and mutually separated non-return layers, a sample pad for detecting hemoglobin, a blood filtering film for detecting glutamic pyruvic transaminase and a flow pad.
The sample processing unit comprises a splitting layer covering the two detection channels and is used for splitting the blood sample to the hemoglobin detection channel and the glutamic-pyruvic transaminase detection channel.
The diversion layer can be hydrophilic mesh cloth material, such as polyester, nylon, etc. Monofilament mesh cloth with larger difference of warp and weft diameters can be used, and the thick wire direction transversely spans two detection channels.
The sample processing unit comprises two independent and mutually separated non-return layers which are respectively arranged in the hemoglobin detection channel and the glutamic-pyruvic transaminase detection channel and are used for preventing a blood sample from being reversely transferred back to the separation layer, and chemical reagents of the hemoglobin detection channel are caused to interfere the normal detection of the glutamic-pyruvic transaminase detection channel through the bridging action of the separation layer.
The non-return layer can be hydrophilic mesh cloth material, such as polyester, nylon, etc. The monofilament mesh cloth with larger difference of warp and weft diameters can be used, the thick wire direction is longitudinally arranged and is mutually perpendicular to the thick wire direction of the flow dividing layer, so that the contact area between the flow dividing layer and the non-return layer is reduced, and the non-return effect is achieved.
The reaction window comprises a hemoglobin detection window and a glutamic pyruvic transaminase reaction window, a reaction film is stuck on the reaction window, and the reaction window is connected with the upper cover through interference fit; the upper cover is provided with a plurality of small columns which are in interference fit with corresponding grooves on the base, and the upper cover and the base can be fixed together in a pressing manner; a round hole is arranged in the middle of the sample adding hole cover and used for adding a blood sample, a plurality of small columns are arranged around the sample adding hole cover and are in interference fit with corresponding grooves on the base, and the sample adding hole cover and the base can be fixed together in a pressing mode.
The reaction window comprises a hemoglobin detection window and a glutamic pyruvic transaminase reaction window, a reaction film is stuck on the reaction window, and a reaction reagent which participates in the chromogenic reaction of hemoglobin or glutamic pyruvic transaminase is solidified on the reaction film and is distributed in a solid state in a reaction film net structure. The reaction membrane can be nitrocellulose membrane, nylon membrane, polyester membrane, polyether sulfone membrane and other materials.
The area of the reaction film is slightly larger than that of the window, so that the reaction film is convenient to adhere to colloid near the window, the reaction film is positioned right above the sample pad (or the flow pad) and keeps a non-contact state with the sample pad (or the flow pad), but the reaction film and the sample pad (or the flow pad) are in a partially overlapped area in the vertical direction, so that the reaction film can be contacted with each other under the laminating control of a matched analysis instrument, and the blood (or serum) sample on the sample pad (or the flow pad) is transferred to the reaction film, so that the color reaction is completed.
The sample pad is solidified with hemolysis reagent, reaction reagent, auxiliary reagent and the like which participate in the chromogenic reaction of the hemoglobin, and the hemolysis reagent, the reaction reagent, the auxiliary reagent and the like are distributed in a solid state in the network structure of the sample pad. The sample pad may be glass fiber, cotton fiber, polyester fiber, etc.
The anti-interference dry chemical combination detection device has a simple structure, is easy to manufacture, can effectively ensure that blood flows from the sample adding hole to the first detection channel and the second detection channel respectively by arranging the flow dividing layer, the first non-return layer and the second non-return layer, does not cause cross contamination or mutual interference caused by backflow, and can facilitate one-time blood adding and two-function detection simultaneously.
Claims (4)
1. The utility model provides an anti-interference dry chemistry allies oneself with detection device, includes base (1), application of sample lid (2), reposition of redundant personnel layer (3), separation piece (4), first detection channel and second detection channel, the middle part of one side of base (1) is provided with separation piece (4), the both sides of separation piece (4) are first detection channel and second detection channel respectively, be provided with first non-return layer (5) in the first detection channel, be provided with second non-return layer (6) in the second detection channel, the top of separation piece (4) sets gradually reposition of redundant personnel layer (3) and application of sample lid (2), reposition of redundant personnel layer (3) cover first detection channel and second detection channel, be provided with application of sample hole (21) on application of sample lid (2);
the shunt layer (3) is formed by mutually perpendicular and cross weaving of first thick threads and first thin threads, the first thick threads are warp threads, the first thin threads are weft threads, and the first thick threads cross the first detection channel and the second detection channel;
the first non-return layer (5) is formed by mutually and perpendicularly intersecting and weaving second thick threads and second fine threads, the second thick threads are warp threads, and the second fine threads are weft threads;
the second non-return layer (6) is formed by mutually and perpendicularly intersecting and weaving third thick threads and third fine threads, the third thick threads are warp threads, and the third fine threads are weft threads;
the second thick line and the third thick line are vertically crossed with the first thick line;
a blood filtering film (51) is further arranged in the first detection channel, and the blood filtering film (51) is arranged below the first non-return layer (5);
a first flow pad (52) is further arranged in the first detection channel, one end of the first flow pad (52) is arranged below the blood filtering membrane (51), and the other end of the first flow pad (52) extends out of the first detection channel;
the device further comprises a first reaction panel (53), wherein the first reaction panel (53) is positioned right above the first flow pad (52), a first reaction through hole is formed in the first reaction panel (53), and a first reaction film is stuck below the first reaction through hole;
a sample pad (61) is further arranged in the second detection channel, one end of the sample pad (61) is arranged below the second non-return layer (6), and the other end of the sample pad (61) extends out of the second detection channel;
a second reaction panel (62) is further arranged in the second detection channel, the second reaction panel (62) is arranged right above the sample pad (61), a second reaction through hole is formed in the second reaction panel (62), and a second reaction film is adhered below the second reaction through hole;
the upper surface of the separation block (4) is higher than the first non-return layer (5) and the second non-return layer (6);
the first thick line, the first thin line, the second thick line, the second thin line, the third thick line and the third thin line are all hydrophilic materials;
the diameter of the first thick line is 2-4 times of the diameter of the first thin line, the diameter of the second thick line is 2-4 times of the diameter of the second thin line, and the diameter of the third thick line is 2-4 times of the diameter of the third thin line;
the first detection channel is a glutamic pyruvic transaminase detection channel;
the second detection channel is a hemoglobin detection channel.
2. The anti-interference dry chemical combination detection device according to claim 1, wherein: the separating block (4) is provided with a clamping groove, the opposite surface of the sample adding cover (2) and the separating block (4) is provided with a protrusion, and the protrusion is in interference fit with the clamping groove.
3. The anti-interference dry chemical combination detection device according to claim 1, wherein: the shunt layer (3), the first non-return layer (5) and/or the second non-return layer (6) are/is made of monofilament mesh cloth.
4. The anti-interference dry chemical combination detection device according to claim 1, wherein: the hydrophilic material is polyester or nylon.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE4005021A1 (en) * | 1990-02-19 | 1991-08-22 | Boehringer Mannheim Gmbh | TEST CARRIER FOR ANALYSIS OF A SAMPLING LIQUID |
| US5628890A (en) * | 1995-09-27 | 1997-05-13 | Medisense, Inc. | Electrochemical sensor |
| US6844149B2 (en) * | 2001-06-29 | 2005-01-18 | International Business Machines Corporation | Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements |
| US20030190690A1 (en) * | 2001-08-10 | 2003-10-09 | Mie Takahashi | Biosensor and method for analyzing blood components using it |
| CN102288747B (en) * | 2011-08-19 | 2013-11-27 | 长沙三诺生物传感技术股份有限公司 | Interference-removing dry chemical quantitative test strip, alanine and aspartate aminotransferase quantitative test strip and test method thereof |
| US9586204B2 (en) * | 2014-06-23 | 2017-03-07 | Xerox Corporation | Paper sensor |
| CN206038690U (en) * | 2016-08-31 | 2017-03-22 | 北京中科圆融生物科技发展有限公司 | Multiple pick -up plate of single -site multichannel immunity chromatography |
| CN206146942U (en) * | 2016-11-08 | 2017-05-03 | 南京大树生物医疗技术股份有限公司 | Multinomial detection device that unites of multichannel dry -type chemistry |
| CN208334386U (en) * | 2018-05-18 | 2019-01-04 | 王义明 | A kind of novel multi-channel colloidal-gold detecting-card based on paper chip |
| CN109580938B (en) * | 2019-01-11 | 2024-08-23 | 广州万孚生物技术股份有限公司 | Loading bottom plate and immunochromatography detection device comprising loading bottom plate |
| CN211978929U (en) * | 2019-10-15 | 2020-11-20 | 南京大树生物医疗技术股份有限公司 | Anti-interference dry chemical combined detection device |
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