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CN110755747A - Self-powered hair growth stimulation device - Google Patents

Self-powered hair growth stimulation device Download PDF

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Publication number
CN110755747A
CN110755747A CN201911088874.6A CN201911088874A CN110755747A CN 110755747 A CN110755747 A CN 110755747A CN 201911088874 A CN201911088874 A CN 201911088874A CN 110755747 A CN110755747 A CN 110755747A
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China
Prior art keywords
electrode
self
hair growth
growth stimulation
stimulation device
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CN201911088874.6A
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Chinese (zh)
Inventor
吴晓龙
许晨
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Individual
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0464Specially adapted for promoting tissue growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0472Structure-related aspects
    • A61N1/0484Garment electrodes worn by the patient

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Electrotherapy Devices (AREA)

Abstract

The invention relates to a self-powered hair growth stimulation device, which comprises a power generation device and a pulse excitation device, wherein the power generation device is connected with the pulse excitation device through a lead, the power generation device is a friction generator, the friction generator comprises a transfer electrode and a friction electrode, the self-powered hair growth stimulation device does not need a battery or complex electronic equipment, is miniaturized and can be implanted into various wearable articles, so that energy can be collected from daily movement of a human body, and skin is stimulated through soft low-frequency electric pulses, so that organisms including the human body are stimulated, dormant hair follicles are induced to be reactivated, and hairs grow out.

Description

Self-powered hair growth stimulation device
Technical Field
The invention relates to the technical field of alopecia treatment, in particular to a self-powered hair growth stimulation device.
Background
Alopecia is a common and disturbing symptom, which always troubles people. Are classified as dermatological deficiencies and/or abnormal hair cycle due to growth factors. It is a common disease in men and women worldwide. In the united states, about 3500 million men and 2100 million women suffer from hair loss in 2015. Currently, the main treatments for hair loss include topical treatment, oral medication and hair transplantation to restore a healthy hair growth cycle. Topical treatment is the most common choice for patients due to painlessness and high absorption. Minoxidil (MNX) and finasteride oral liquid are two drugs approved by the U.S. food and drug administration and are widely used for preventing and treating alopecia. However, as MNX and finasteride only reduce hair loss, but not increase hair loss rate significantly. Thus, the patient must continue to use for a period of time to produce a lasting effect. In addition, MNX and finasteride may cause serious side effects such as sexual dysfunction, hypertrophy and fetal defects. Instead of drug treatment, hair transplantation can help patients develop new hairs, but several rounds of surgery are also required, which is associated with high costs, discomfort and time investment. Thus, painless, pharmacologic, cost effective, and convenient methods are always needed to treat hair loss. Currently, several promising non-drug therapeutic approaches such as thermal, laser and electrical stimulation have been developed and are gradually entering clinical research/practice. Among them, electrical stimulation can induce non-invasive biological effects, called electro-proliferation (ETG). Although the optimal ETG parameters have not been clinically proven, the range of alternating Electric Field (EF) is typically 0.1-10V/cm, with frequencies <15 Hz, with negligible damage to tissue. ETG can enhance the influx of calcium ions into dermal papilla cells through voltage-gated transmembrane ion channels, promote ATP synthesis in mitochondria, activate protein kinases, and stimulate protein synthesis and cell division. Therefore, it is considered that the ETG effect can regulate the secretion of various hair growth factors, promote the proliferation of Hair Follicles (HF), prolong the anagen phase, and finally promote the regeneration of hairs. Although state-of-the-art extracorporeal treatment devices have been reduced in size to accommodate wearable devices, the overall system remains bulky and inconvenient for day-to-day treatment limited by battery capacity and output current.
Various pharmacological and non-pharmacological treatments have been extensively studied to achieve the desired hair regrowth effect with respect to hair loss. As a non-pharmacological physical approach, the field of physiologically appropriate alternating current plays a key role in the field of regenerative tissue engineering.
Disclosure of Invention
In order to solve the above technical problem, the present invention provides a self-powered hair growth stimulation device.
The technical scheme of the invention is as follows: a self-powered hair growth stimulation device comprises a power generation device and a pulse excitation device, wherein the power generation device and the pulse excitation device are connected through a lead.
Preferably, the power generation device includes, but is not limited to, one of a friction generator, a piezoelectric generator, a photoelectric generator, and a thermal generator.
Preferably, the power generation device is a friction generator.
Preferably, the triboelectric generator comprises a transfer electrode and a triboelectric electrode.
Preferably, the transfer electrodes are annular array electrodes with 2n layers of annular pole pieces, the pole pieces of the transfer electrodes are provided with gaps, the pole piece gaps of every two adjacent transfer electrodes are opposite in direction, and odd-numbered pole pieces and even-numbered pole pieces of the transfer electrodes are respectively connected together; the friction electrode is an annular array electrode with n layers of annular pole pieces, and the pole pieces of the friction electrode are in a closed annular shape.
Preferably, the transfer electrode is installed on a smooth plastic plate, and the rubbing electrode is located below the smooth plastic plate and connected with the transfer electrode through an elastic plastic tape.
Preferably, a first resin substrate covers the transfer electrode, and the rubbing electrode is mounted on a second resin substrate.
Preferably, the power generation device and the pulse excitation device are both mounted on a third resin substrate, and the outer sides of the second resin substrate and the third resin substrate are respectively connected with the first transparent organic thin film and the second transparent organic thin film.
Preferably, the material of smooth plastic slab is nanostructured's polytetrafluoroethylene, the material of plastic tape is the copolyester, first resin board the material of second resin board with the third resin board is polyethylene glycol terephthalate, first transparent organic film with the material of second transparent organic film is the polyimide.
Preferably, the pulse excitation device is an interdigital electrode, and two pole pieces of the interdigital electrode are respectively connected with the odd pole piece layer and the even pole piece layer of the transfer electrode by using conducting wires.
The invention has the beneficial effects that:
the device does not need a battery or complex electronic equipment, is miniaturized, can be implanted into various wearable articles, can collect energy from daily movement of a human body, stimulates the skin through soft low-frequency electric pulses, thereby stimulating organisms including the human body, inducing the dormant hair follicles to be reactivated and growing hairs.
Furthermore, since the electrical impulses are very gentle and do not penetrate to a depth beyond the outermost layers of the scalp, the device does not cause any undesirable side effects.
Due to the device that collects energy from the daily movements of the human body, the skin can be stimulated by soft, low-frequency electrical pulses, thereby inducing dormant hair follicles to reactivate hair production. Therefore, the device can be used as an effective intervention means in the early stage of alopecia. In addition, the device can improve the secretion of vascular endothelial growth factor and keratinocyte growth factor, thereby relieving hair keratin disorder, increasing the number of hair follicles, and promoting hair regeneration.
The self-powered, non-pharmacological nature of the present invention provides an effective hair regrowth strategy.
Drawings
FIG. 1 is a schematic front view of the present invention;
FIG. 2 is a schematic top view of the present invention;
FIG. 3 is a schematic bottom view of the present invention;
FIG. 4 is a schematic structural diagram of the connection of the transfer electrodes and the interdigital electrodes;
FIG. 5 is a schematic structural view of a rubbing electrode;
FIG. 6 is a comparison of the dimensional relationship of the transfer electrode and the rubbing electrode;
FIG. 7 is a schematic diagram of the operation of a friction generator;
in the figure: 1. the solar cell comprises a power generation device, 1-1 transfer electrodes, 1-2 friction electrodes, 2 pulse excitation devices, 2-1 interdigital electrodes, 3 conducting wires, 4 smooth plastic plates, 5 first resin substrates, 6 second resin substrates, 7 first transparent organic films, 8 plastic tapes, 9 third resin substrates and 10 second transparent organic films.
Detailed Description
Detailed description of the invention with reference to fig. 1-7:
a self-powered hair growth stimulation device is disclosed, as shown in figures 1-5, and comprises a power generation device 1 and a pulse excitation device 2, wherein the power generation device 1 and the pulse excitation device 2 are connected through a lead 3, the power generation device 1 is a friction generator, the friction generator comprises a transfer electrode 1 and a friction electrode 1-2, wherein the transfer electrode 1 is an annular array electrode with 2n layers of annular pole pieces, the pole pieces of the transfer electrode 1 are provided with gaps, the direction of the gap of each two adjacent pole pieces of the transfer electrode 1 is opposite, and the odd pole pieces and the even pole pieces of the transfer electrode 1 are respectively connected together; the friction electrode 1-2 is an annular array electrode with n layers of annular pole pieces, the pole pieces of the friction electrode 1-2 are in a closed annular shape, the transfer electrode 1 is installed on the smooth plastic plate 4, and the friction electrode 1-2 is located below the smooth plastic plate 4 and connected with the transfer electrode 1 through an elastic plastic tape 8; the pulse excitation device 2 is an interdigital electrode 2-1, and two pole pieces of the interdigital electrode 2-1 are respectively connected with an odd pole piece and an even pole piece of the transfer electrode 1 by a lead 3; the upper part of the transfer electrode 1 is covered with a first resin substrate 5, the friction electrode 1-2 is arranged on a second resin substrate 6, the power generation device 1 and the pulse excitation device 2 are both arranged on a third resin substrate 9, and the outer sides of the second resin substrate 6 and the third resin substrate 9 are respectively connected with a first transparent organic film 7 and a second transparent organic film 10.
In the invention: the material of the smooth plastic plate 4 is Polytetrafluoroethylene (PTFE) with a nano structure, the material of the plastic tape 8 is copolyester (Ecoflex), the materials of the first resin plate, the second resin plate and the third resin plate are all polyethylene terephthalate (PET), and the materials of the first transparent organic film 7 and the second transparent organic film 10 are all polyimide (polyimide).
Referring to fig. 6, in the transfer electrode 1, the width (dG) of the pole piece of the rubbing electrode 1-2 is twice the width (dT) of the pole piece of the transfer electrode 1, and the number (n) of pole piece layers of the rubbing electrode 1-2 is half the number (2 n) of pole piece layers of the transfer electrode 1.
Referring to fig. 7, the rubbing electrode 1-2 of the present invention is connected to the transfer electrode 1 only by the plastic tape 8, the plastic tape 8 has elasticity, the rubbing electrode 1-2 and the smooth plastic plate 4 under the transfer electrode 1 can slide relatively to each other, so that rubbing is performed, electrons in the rubbing electrode 1-2 move toward the smooth plastic plate 4, and then negative charges and positive charges are induced, and the negative charges and the positive charges are uniformly distributed on the surfaces of PTFE and CGE, respectively, under an open circuit condition, locally unbalanced charges generate a potential difference (V ≠ 0) between the odd pole piece and the even pole piece of the transfer electrode 1, and when the rubbing electrode 1-2 is located under the transfer electrode 1, the potential reaches zero (VPP = 0) due to the balanced potential, so that, as the rubbing electrode 1-2 moves between the odd pole piece and the even pole piece of the transfer electrode 1, a periodic cyclical ac voltage output can be obtained.
The device does not need a battery or complex electronic equipment, is miniaturized, can be implanted into various wearable articles, can collect energy from daily movement of a human body, stimulates the skin through soft low-frequency electric pulses, thereby stimulating organisms including the human body, inducing the dormant hair follicles to be reactivated and growing hairs. Furthermore, since the electrical impulses are very gentle and do not penetrate to a depth beyond the outermost layers of the scalp, the device does not cause any undesirable side effects. Due to the device that collects energy from the daily movements of the human body, the skin can be stimulated by soft, low-frequency electrical pulses, thereby inducing dormant hair follicles to reactivate hair production. Therefore, the device can be used as an effective intervention means in the early stage of alopecia. In addition, the device can improve the secretion of vascular endothelial growth factor and keratinocyte growth factor, thereby relieving hair keratin disorder, increasing the number of hair follicles, and promoting hair regeneration. The self-powered, non-pharmacological nature of the present invention provides an effective hair regrowth strategy.

Claims (10)

1. A self-powered hair growth stimulation device characterized by: the pulse excitation device is connected with the power generation device through a lead.
2. A self-powered hair growth stimulation device according to claim 1, characterized in that: the power generation device includes but is not limited to one of a friction generator, a piezoelectric generator, a photoelectric generator and a thermal energy generator.
3. A self-powered hair growth stimulation device according to claim 1, characterized in that: the power generation device is a friction generator.
4. A self-powered hair growth stimulation device according to claim 3, characterized in that: the triboelectric generator includes a transfer electrode and a triboelectric electrode.
5. Self-powered hair growth stimulation device according to claim 4, characterized in that: the transfer electrodes are annular array electrodes with 2n layers of annular pole pieces, the pole pieces of the transfer electrodes are provided with gaps, the pole piece gaps of every two adjacent transfer electrodes are opposite in direction, and odd-numbered pole pieces and even-numbered pole pieces of the transfer electrodes are respectively connected together; the friction electrode is an annular array electrode with n layers of annular pole pieces, and the pole pieces of the friction electrode are in a closed annular shape.
6. A self-powered hair growth stimulation device according to claim 5, characterized in that: the transfer electrode is installed on the smooth plastic plate, and the friction electrode is located below the smooth plastic plate and connected with the transfer electrode through an elastic plastic tape.
7. A self-powered hair growth stimulation device according to claim 6, characterized in that: a first resin substrate covers the transfer electrode, and the friction electrode is mounted on a second resin substrate.
8. A self-powered hair growth stimulation device according to claim 7, characterized in that: the power generation device and the pulse excitation device are both arranged on a third resin substrate, and the outer sides of the second resin substrate and the third resin substrate are respectively connected with a first transparent organic film and a second transparent organic film.
9. A self-powered hair growth stimulation device according to claim 8, characterized in that: the material of smooth plastic slab is nanostructured's polytetrafluoroethylene, the material of plastic tape is the copolyester, first resin board the second resin board with the material of third resin board is polyethylene glycol terephthalate, first transparent organic film with the material of the transparent organic film of second is the polyimide.
10. A self-powered hair growth stimulation device according to any of claims 5-9, characterized in that: the pulse excitation device is an interdigital electrode, and two pole pieces of the interdigital electrode are respectively connected with odd pole pieces and even pole pieces of the transfer electrode by conducting wires.
CN201911088874.6A 2019-11-08 2019-11-08 Self-powered hair growth stimulation device Pending CN110755747A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022042383A1 (en) * 2020-08-28 2022-03-03 王珏 Self-driving pulse microcurrent cosmetic mask

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CN1235851A (en) * 1998-05-20 1999-11-24 范良藻 Electric pulse recovery device
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CN104467515A (en) * 2014-12-02 2015-03-25 北京科技大学 Multi-unit nanometer hydroelectric generator and manufacturing method thereof
CN205162023U (en) * 2015-12-07 2016-04-20 山东涵信光电科技有限公司 Intelligence cap
CN107233669A (en) * 2017-06-08 2017-10-10 青石医疗科技有限公司 Multifunctional physiotherapy instrument
CN108233762A (en) * 2018-03-22 2018-06-29 大连理工大学 A kind of flexible wearable friction nanometer power generator of comprehensive multi-mode collecting mechanical energy
CN208078921U (en) * 2018-03-22 2018-11-09 大连理工大学 A kind of flexible wearable friction nanometer power generator of comprehensive multi-mode collecting mechanical energy
CN208389186U (en) * 2017-07-06 2019-01-18 深圳华瑞技术有限公司 A kind of novel physiotherapy equipment
CN109809359A (en) * 2019-01-10 2019-05-28 北方工业大学 A 2.5D interdigital electrode fabrication method and interdigital electrode
CN110201301A (en) * 2019-06-14 2019-09-06 清华大学 A kind of wound healing device based on triboelectricity

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1235851A (en) * 1998-05-20 1999-11-24 范良藻 Electric pulse recovery device
US20140088670A1 (en) * 2012-09-25 2014-03-27 Ines Verner Rashkovsky Devices and methods for stimulation of hair growth
CN103368449A (en) * 2013-01-28 2013-10-23 国家纳米科学中心 Nanometer electric generator utilizing sliding friction
CN203377811U (en) * 2013-06-21 2014-01-01 纳米新能源(唐山)有限责任公司 Friction generator
CN104426417A (en) * 2013-08-30 2015-03-18 国家纳米科学中心 Friction power generator capable of generating alternating current output and power generator set
CN203883696U (en) * 2014-04-29 2014-10-15 国家纳米科学中心 Power generation system suitable for fluctuating liquid
CN204207098U (en) * 2014-11-06 2015-03-18 纳米新能源(唐山)有限责任公司 A kind of electro photoluminescence brassiere of self power generation
CN104467515A (en) * 2014-12-02 2015-03-25 北京科技大学 Multi-unit nanometer hydroelectric generator and manufacturing method thereof
CN205162023U (en) * 2015-12-07 2016-04-20 山东涵信光电科技有限公司 Intelligence cap
CN107233669A (en) * 2017-06-08 2017-10-10 青石医疗科技有限公司 Multifunctional physiotherapy instrument
CN208389186U (en) * 2017-07-06 2019-01-18 深圳华瑞技术有限公司 A kind of novel physiotherapy equipment
CN108233762A (en) * 2018-03-22 2018-06-29 大连理工大学 A kind of flexible wearable friction nanometer power generator of comprehensive multi-mode collecting mechanical energy
CN208078921U (en) * 2018-03-22 2018-11-09 大连理工大学 A kind of flexible wearable friction nanometer power generator of comprehensive multi-mode collecting mechanical energy
CN109809359A (en) * 2019-01-10 2019-05-28 北方工业大学 A 2.5D interdigital electrode fabrication method and interdigital electrode
CN110201301A (en) * 2019-06-14 2019-09-06 清华大学 A kind of wound healing device based on triboelectricity

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022042383A1 (en) * 2020-08-28 2022-03-03 王珏 Self-driving pulse microcurrent cosmetic mask

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Application publication date: 20200207