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CN110743004A - Astaxanthin direct drinking powder composition with whitening function and preparation method and application thereof - Google Patents

Astaxanthin direct drinking powder composition with whitening function and preparation method and application thereof Download PDF

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Publication number
CN110743004A
CN110743004A CN201911184890.5A CN201911184890A CN110743004A CN 110743004 A CN110743004 A CN 110743004A CN 201911184890 A CN201911184890 A CN 201911184890A CN 110743004 A CN110743004 A CN 110743004A
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astaxanthin
powder
powder composition
drink
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陈晓宇
廖良君
徐庆海
张秀凯
刘世英
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Tianjin Vitality Biotechnology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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Abstract

The invention discloses an astaxanthin direct drinking powder composition with a whitening function, and a preparation method and application thereof, wherein the astaxanthin direct drinking powder composition comprises the following components in parts by weight: 3-30 parts of astaxanthin microcapsule powder, 2-20 parts of haematococcus pluvialis powder, 0.2-10 parts of collagen peptide and 0.2-5 parts of ascorbic acid; the preparation method comprises the following steps: mixing the above materials at a certain proportion, making into 60-80 mesh granules, drying, and packaging. The astaxanthin direct drinking powder composition with the whitening function achieves the effects of moistening skin and increasing the skin whitening degree by reasonably composing and matching various components, resisting oxidation, reducing free radicals, resisting saccharification, providing collagen and the like, and is suitable for people who love beauty, people with dark and dark skin, rough skin and the like; is convenient to carry and safe to eat; the raw materials are easy to obtain, the conditions and equipment required by preparation are simple, the process is simple and controllable, and the method has important practical popularization value.

Description

Astaxanthin direct drinking powder composition with whitening function and preparation method and application thereof
Technical Field
The invention belongs to the field of medicines and health-care products, and particularly relates to an astaxanthin direct drinking powder composition with a whitening function, and a preparation method and application thereof.
Background
With the rapid growth of social economy, the whitening market also grows rapidly. Based on the holding of Asian consumers in the whitening field, a plurality of brands and related products with whitening efficacy emerge in the market, and the existing whitening external application products in the market have quick effect but certain potential safety hazards. Therefore, the oral product has the functions of conditioning the body, resisting oxidation, removing free radicals and the like, thereby having the whitening effect and wide market prospect.
By orally administering antioxidant products (such as astaxanthin and ascorbic acid), dark yellow skin color and pigmentation during early aging of skin can be reduced and prevented, fine lines, mottle and erythema can be improved, pores can be shrunk, acne can be reduced, and skin metabolism can be improved.
In addition, the existing patent applications related to whitening products mainly relate to skin care products and cosmetics, while the patent of whitening health-type composition oral products is less. The Chinese patent application with the application number of 201510119657.4 discloses a beautifying and health-care drink with whitening and anti-wrinkle effects, which is prepared by processing yacon, compounding other traditional Chinese medicines such as ginger, medlar, rose, rosemary and the like, adding chitin and probiotics for fermentation, adjusting the taste with milk powder, and promoting bifidobacterium and lactobacillus fermentation to a better quantitative value through fruit oligosaccharide, chitin and xylitol of the yacon. Under the combined action of the traditional Chinese medicines and the probiotics, the health-care beverage can regulate endocrine, maintain beauty and keep young, particularly can whiten skin, lighten spots, promote skin regeneration and lighten wrinkles; chinese invention patent application with application number of 201310230185.0 discloses a Chinese medicinal composition for whitening skin and application thereof, wherein the Chinese medicinal composition is prepared from the following raw material medicaments in part by weight: the Chinese medicinal composition is prepared by crushing raw medicinal materials, sieving the raw medicinal materials with a 80-mesh sieve, wrapping the raw medicinal materials in gauze, putting the gauze in a container filled with cold boiled water, decocting the gauze until the gauze is boiled and continuously decocting the gauze for 6 to 8 hours, and has the remarkable effects of activating blood circulation and removing obstruction in channels and whitening skin.
In summary, most of the existing whitening products are external products such as cosmetics, skin care products and masks, but the whitening products are fewer in the aspect of conditioning the interior of the body, and the rare conditioning whitening products are also traditional Chinese medicine substances, have more practical product problems from easy production to side effects and the like, are not good in taking mode and taste, and are not easy to be favored by women.
So far, no report about the application of astaxanthin microcapsule powder, haematococcus pluvialis powder, collagen peptide, ascorbic acid and the like in preparing an internal product with a whitening function is found.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide an astaxanthin direct drinking powder composition with a whitening function.
The invention also aims to provide a preparation method of the astaxanthin direct drinking powder composition.
The invention also aims to provide application of the astaxanthin direct drinking powder composition.
The invention adopts the following technical scheme:
an astaxanthin direct drinking powder composition with a whitening function comprises the following components in parts by weight:
3-30 parts of astaxanthin microcapsule powder, 2-20 parts of haematococcus pluvialis powder, 0.2-10 parts of collagen peptide and 0.2-5 parts of ascorbic acid.
Preferably, the astaxanthin direct drinking powder composition with the whitening function provided by the invention comprises the following components in parts by weight:
12-22.5 parts of astaxanthin microcapsule powder, 8.5-13.2 parts of haematococcus pluvialis powder, 0.75-3.6 parts of collagen peptide and 0.35-2.5 parts of ascorbic acid.
Further preferably, the astaxanthin direct drinking powder composition with the whitening function provided by the invention further comprises the following components in parts by weight:
5-45 parts of erythritol, 3-40 parts of orange powder, 3-35 parts of resistant dextrin, 2-15 parts of lemon powder, 0.2-5 parts of citric acid and 0.04-3 parts of edible essence.
Still further preferably, the astaxanthin direct drinking powder composition with the whitening function provided by the invention comprises the following components in parts by weight:
30 parts of erythritol, 20 parts of orange powder, 20 parts of resistant dextrin, 15 parts of astaxanthin microcapsule powder, 10 parts of haematococcus pluvialis powder, 3 parts of lemon powder, 1 part of collagen peptide, 0.5 part of ascorbic acid, 0.5 part of citric acid and 0.1 part of edible essence.
The astaxanthin direct drinking powder composition with the whitening function provided by the invention comprises the following components in parts by weight:
the astaxanthin microcapsule powder consists of sodium starch octenyl succinate, haematococcus pluvialis, isomaltooligosaccharide, ascorbic acid and sodium ascorbate, wherein the content of astaxanthin is 2.1-5.5 wt%.
The collagen peptide is polypeptide and oligopeptide substances which are obtained by enzymolysis of animal bones and fur and are rich in small molecules with the molecular weight of 700-5000 Da.
The content of astaxanthin in the haematococcus pluvialis powder is 1.75-2.58 wt%.
The content of VC in the ascorbic acid is more than 95 wt%.
The invention also provides a preparation method of the astaxanthin direct drinking powder composition with the whitening function, which comprises the following steps:
mixing the above materials at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
The invention also provides application of the astaxanthin direct drinking powder composition with the whitening function in preparation of foods, medicines or health-care products with the whitening function.
The astaxanthin direct drinking powder composition with the whitening function provided by the invention can be increased or reduced according to corresponding proportion during production, for example, the weight can be increased or reduced by kilogram or ton in large-scale production and by gram in small-scale production, but the weight proportion of the raw materials among the components is unchanged.
The astaxanthin direct drinking powder composition with the whitening function has the following advantages:
(1) the astaxanthin direct drinking powder product with the whitening function provided by the invention takes astaxanthin microcapsule powder, haematococcus pluvialis powder, collagen peptide and ascorbic acid as main components, so that various components are reasonably combined and shared, and the effects of moistening skin and increasing skin whitening degree are achieved by means of antioxidation, free radical reduction, saccharification resistance, collagen provision and the like, so that the product is suitable for people who love beauty, people with dark and dark skin, rough skin and the like;
(2) the astaxanthin direct drinking powder product with the whitening function is convenient to carry, safe and reliable to eat, moderate in taste and special in fragrance, and can be directly poured into the mouth for taking;
(3) the crowd experiments prove that after the astaxanthin direct drinking powder product with the whitening function is taken, the skin state is obviously improved and whitened, and the functional composition provided by the invention can effectively improve the skin color and roughness;
(4) the astaxanthin direct drinking powder product with the whitening function provided by the invention has the advantages of easily available raw materials, simple preparation conditions and equipment, simple and controllable process and very important practical popularization value.
Detailed Description
The following describes the embodiments of the present invention in further detail with reference to specific examples.
The following examples are intended to illustrate the present invention, but not to limit the scope of the invention, which is defined by the claims.
Unless otherwise specified, the test reagents and materials used in the examples of the present invention are commercially available.
The raw material sources used in the examples of the invention and the comparative examples are as follows:
the astaxanthin microcapsule powder is a product sold in the Xian Saiyang biotechnology limited company, and is prepared from sodium starch octenylsuccinate, Haematococcus pluvialis, isomaltooligosaccharide, ascorbic acid and sodium ascorbate according to the mass ratio of 5: 90: 3: 1: 1, wherein the content of astaxanthin is 4.8 wt%.
The collagen peptide is a product sold in Beijing Shengnuo biotechnology limited company, and is specifically polypeptide and oligopeptide substances which are obtained by enzymolysis of animal bones and fur and are rich in small molecules with the molecular weight of 700-5000 Da.
The astaxanthin content in the haematococcus pluvialis powder is 1.98 wt%.
The ascorbic acid used had a VC content of 97.5% by weight.
The erythritol 3, the willow orange powder, the resistant dextrin, the lemon powder, the citric acid and the edible essence are all commercially available products.
In the preparation process of the invention, the used means are all conventional technical means in the field unless otherwise specified.
Example 1
The embodiment provides an astaxanthin direct drinking powder composition with a whitening function.
1. Component (parts by weight)
Figure BDA0002292163950000051
2. Preparation method
Mixing the above components at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
Example 2
The embodiment provides an astaxanthin direct drinking powder composition with a whitening function.
1. Component (parts by weight)
Figure BDA0002292163950000052
Figure BDA0002292163950000061
2. Preparation method
Mixing the above components at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
Example 3
The embodiment provides an astaxanthin direct drinking powder composition with a whitening function.
1. Component (parts by weight)
Figure BDA0002292163950000062
2. Preparation method
Mixing the above components at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
Comparative example 1
The embodiment provides an astaxanthin direct drinking powder composition with a whitening function.
1. Component (parts by weight)
Figure BDA0002292163950000071
2. Preparation method
Mixing the above components at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
Comparative example 2
The embodiment provides an astaxanthin direct drinking powder composition with a whitening function.
1. Component (parts by weight)
Figure BDA0002292163950000072
2. Preparation method
Mixing the above components at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
Functional experimental testing: in order to prove that the astaxanthin direct drinking powder composition disclosed by the embodiment of the invention has an obvious promotion effect on whitening, a test of a volunteer is selected for proving, and the specific process is as follows:
example 1
250 skin dark volunteers were randomized to diet, with 125 males and 125 females randomized into five groups of 25 males and 25 females each.
Group 1 tasted the astaxanthin drink powder composition of example 1;
group 2 tasted the astaxanthin drink powder composition of example 2;
group 3 tasted the astaxanthin drink powder composition of example 3;
group 4 tasted the astaxanthin drink powder composition of comparative example 1;
group 5 was fed the astaxanthin drink powder composition of comparative example 2.
The eating method comprises the following steps:
each group of people takes the astaxanthin direct drinking powder composition of 15g dissolved in 50-100mL of warm water every night, and the final whitening effect is counted.
The following table 1 shows the statistical results of the effect of the experimental examples of the present invention for each group of test feeders.
Table 1 statistical comparison table of whitening effect of each group of test takers in experimental example of the present invention
The results of table 1 show that the astaxanthin direct drinking powder composition provided by the embodiment of the invention can effectively promote the whitening of human body, has an effective rate of up to 100%, is suitable for beauty lovers, people with dark and dark skin, rough skin and the like, and can effectively improve the color and the roughness of the skin; the astaxanthin direct drinking powder product with the whitening function provided by the embodiment of the invention is convenient to carry, safe and reliable to eat, moderate in taste and special in fragrance, and can be directly poured into the mouth for taking; the astaxanthin direct drinking powder product with the whitening function provided by the invention has the advantages of easily available raw materials, simple preparation conditions and equipment, simple and controllable process and very important practical popularization value.
Finally, while the invention has been described in detail by way of general description and specific embodiments, it will be apparent to those skilled in the art that certain changes and modifications may be made thereto without departing from the scope of the invention. Accordingly, such modifications and improvements are intended to be within the scope of the invention as claimed.

Claims (10)

1. The astaxanthin direct drinking powder composition with the whitening function is characterized by comprising the following components in parts by weight:
3-30 parts of astaxanthin microcapsule powder, 2-20 parts of haematococcus pluvialis powder, 0.2-10 parts of collagen peptide and 0.2-5 parts of ascorbic acid.
2. The astaxanthin drink powder composition according to claim 1, comprising the following components in parts by weight:
12-22.5 parts of astaxanthin microcapsule powder, 8.5-13.2 parts of haematococcus pluvialis powder, 0.75-3.6 parts of collagen peptide and 0.35-2.5 parts of ascorbic acid.
3. The astaxanthin drink-through powder composition according to claim 1 or 2, further comprising the following components in parts by weight:
5-45 parts of erythritol, 3-40 parts of orange powder, 3-35 parts of resistant dextrin, 2-15 parts of lemon powder, 0.2-5 parts of citric acid and 0.04-3 parts of edible essence.
4. An astaxanthin drink-through powder composition according to any one of claims 1 to 3, characterized by consisting of the following components in parts by weight:
30 parts of erythritol, 20 parts of orange powder, 20 parts of resistant dextrin, 15 parts of astaxanthin microcapsule powder, 10 parts of haematococcus pluvialis powder, 3 parts of lemon powder, 1 part of collagen peptide, 0.5 part of ascorbic acid, 0.5 part of citric acid and 0.1 part of edible essence.
5. An astaxanthin drink-through powder composition according to any one of claims 1 to 4, characterized in that the astaxanthin microcapsule powder consists of sodium starch octenyl succinate, Haematococcus pluvialis, isomaltooligosaccharide, ascorbic acid and sodium ascorbate, wherein the content of astaxanthin is 2.1-5.5 wt%.
6. An astaxanthin drink-through powder composition according to any one of claims 1-4, characterized in that the collagen peptide is polypeptide and oligopeptide substance which is obtained by enzymolysis of animal bones and fur and is rich in small molecules with the molecular weight of 700-5000 Da.
7. An astaxanthin drink-through powder composition according to any one of claims 1 to 4, characterized in that the content of astaxanthin in the Haematococcus pluvialis powder is 1.75-2.58 wt%.
8. An astaxanthin drink-through powder composition according to any one of claims 1-4, characterized in that the content of VC in the ascorbic acid is more than 95 wt%.
9. A method of preparing an astaxanthin drink-through powder composition according to any one of claims 1 to 8, comprising the steps of: mixing the above materials at a certain proportion, making into 60-80 mesh granules, drying, and packaging.
10. Use of an astaxanthin drink-through powder composition according to any one of claims 1 to 8 for the preparation of food, pharmaceutical or health care products with whitening effect.
CN201911184890.5A 2019-11-27 2019-11-27 Astaxanthin direct drinking powder composition with whitening function and preparation method and application thereof Pending CN110743004A (en)

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Cited By (6)

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Publication number Priority date Publication date Assignee Title
CN111363658A (en) * 2020-03-05 2020-07-03 何凤霞 A beverage containing Haematococcus pluvialis extract (astaxanthin) and its preparation method
CN111972584A (en) * 2020-07-13 2020-11-24 荣成市森维迪生物科技有限公司 Astaxanthin-containing anti-aging solid beverage
CN112494454A (en) * 2020-12-04 2021-03-16 宁波泰一健康产业有限公司 DHA-containing oral instant microcapsule powder and preparation method and application thereof
CN113261634A (en) * 2021-06-16 2021-08-17 江苏格局生物医药科技有限公司 Beverage process containing natural astaxanthin
CN114558117A (en) * 2022-02-21 2022-05-31 沈阳药大生物科技有限公司 Youth element composition for nourishing and beautifying and preparation method thereof
CN117562195A (en) * 2023-12-07 2024-02-20 浙江索契壹营养科技有限公司 Chinese and western compound beverage for whitening, removing freckles and resisting wrinkles, and preparation method and application thereof

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US20180168951A1 (en) * 2015-06-26 2018-06-21 Colltec Laboratories Limited Formulation
CN108434443A (en) * 2018-05-28 2018-08-24 广东康侨药业有限公司 A kind of whitening antioxidation composition and application thereof
CN109662234A (en) * 2019-01-17 2019-04-23 云南龙布瑞生物科技有限公司 A kind of Astaxanthin In Haematococcus Pluvialis solid beverage adjusting women skin, anti-aging

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KR20050096556A (en) * 2004-03-31 2005-10-06 정세영 Skin whitening ingredients containing astaxanthin
JP2007320891A (en) * 2006-05-31 2007-12-13 Im Press Kk Oral composition for promoting skin beauty
CN102335420A (en) * 2011-10-19 2012-02-01 宁波红龙生物科技有限公司 Composition containing haematococcus extract and collagen peptide and preparation method for composition
US20180168951A1 (en) * 2015-06-26 2018-06-21 Colltec Laboratories Limited Formulation
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CN108434443A (en) * 2018-05-28 2018-08-24 广东康侨药业有限公司 A kind of whitening antioxidation composition and application thereof
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111363658A (en) * 2020-03-05 2020-07-03 何凤霞 A beverage containing Haematococcus pluvialis extract (astaxanthin) and its preparation method
CN111972584A (en) * 2020-07-13 2020-11-24 荣成市森维迪生物科技有限公司 Astaxanthin-containing anti-aging solid beverage
CN112494454A (en) * 2020-12-04 2021-03-16 宁波泰一健康产业有限公司 DHA-containing oral instant microcapsule powder and preparation method and application thereof
CN113261634A (en) * 2021-06-16 2021-08-17 江苏格局生物医药科技有限公司 Beverage process containing natural astaxanthin
CN114558117A (en) * 2022-02-21 2022-05-31 沈阳药大生物科技有限公司 Youth element composition for nourishing and beautifying and preparation method thereof
CN117562195A (en) * 2023-12-07 2024-02-20 浙江索契壹营养科技有限公司 Chinese and western compound beverage for whitening, removing freckles and resisting wrinkles, and preparation method and application thereof
CN117562195B (en) * 2023-12-07 2024-10-15 浙江索契壹营养科技有限公司 Chinese and western compound beverage for whitening, removing freckles and resisting wrinkles, and preparation method and application thereof

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