CN110720632A - Nutrient composition for late pregnancy and preparation method and application thereof - Google Patents
Nutrient composition for late pregnancy and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a nutrient composition for late pregnancy and a preparation method and application thereof, wherein the composition comprises the following raw materials: calcium carbonate, ferrous fumarate, zinc gluconate, selenium-enriched yeast, copper gluconate, retinyl acetate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, nicotinic acid, folic acid, L-ascorbic acid, vitamin K1, D-calcium pantothenate, and D-alpha-tocopherol; the auxiliary materials comprise: microcrystalline cellulose, crospovidone, povidone K30, sodium starch octenylsuccinate, dextrin, maltodextrin, magnesium stearate, sucrose, edible corn starch, acacia, tricalcium phosphate, dl-alpha-tocopherol, silicon dioxide, and a coating premix. The invention aims at the physiological characteristics and the nutritional requirements of pregnant women in late pregnancy, emphasizes the gold proportion of nutrition in each stage, provides microelements such as calcium, iron, zinc, selenium, copper and the like and vitamins required by the pregnant women in late pregnancy and fetuses, is beneficial to eliminating or lightening the pregnancy reaction in late pregnancy, improving the growth and development indexes of the fetuses, and preventing the pregnancy fatigues such as the birth defects of the fetuses and the like.
Description
Technical Field
The invention relates to the technical field of pregnant woman nutritional health products, in particular to a nutrient composition for late pregnancy and a preparation method and application thereof.
Background
Late pregnancy means pregnancy of 7-9 months, starting from 28 weeks of the pregnant woman until delivery (40 weeks). During this period, the growth and development of the fetus are more rapid, especially the brain cells are increased, and the influence of nutrition on the fetus is more important than during the first two pregnancy. Therefore, the pregnant women need to increase the intake of high-quality protein, calcium and iron in order to prepare for the delivery and lactation period. Pregnant women in late pregnancy are easy to have symptoms of palpitation, shortness of breath, gastrectasia, heartburn, poor appetite, cramp of shank and even diabetes. In addition, the pregnant women in late pregnancy have mild hypertension and edema, and salt intake must be controlled.
The total dietary amount of women in the late pregnancy period in China basically meets the physiological requirements, but the dietary structure is not scientific and reasonable, the dietary nutrition is unbalanced, and the intake of calcium, iron and zinc is insufficient. In order to ensure the nutritional requirements of pregnant women in late pregnancy, pregnant women should eat less and more foods; in addition, the nutrition supplement is required to follow the suggestions of doctors or dieticians, reasonably arrange meals, scientifically supplement nutrition and supplement special nutrition supplements for pregnancy when necessary. However, the existing products in the market share one formula for four stages of pregnancy, and no special nutritional health-care food for late pregnancy is provided aiming at the characteristics of the late pregnancy of pregnant women.
Disclosure of Invention
The invention aims to provide a nutrient composition for late pregnancy aiming at the development characteristics and nutritional requirements of a fetus in the late pregnancy of a pregnant woman, and the nutrient composition is an ideal health-care food for the late pregnancy of the pregnant woman.
The technical scheme adopted by the invention for solving the technical problem is as follows:
the nutrient composition for the pregnant women and the later period comprises the following raw materials in parts by weight:
preferably, the nutrient composition for the pregnant and late period comprises the following raw materials in parts by weight:
furthermore, the nutrient composition for the later stage of pregnancy comprises 0-5 parts of enzyme by weight.
Wherein the ferment is one or two of protease and oxidoreductase.
Furthermore, the nutrient composition for the later stage of pregnancy is mixed with pharmaceutically acceptable auxiliary materials to prepare tablets, granules or capsules.
Preferably, the raw materials are mixed with the following auxiliary materials in parts by weight to prepare tablets:
more preferably, the composition is mixed with the following auxiliary materials in parts by weight to prepare a tablet:
the invention also provides the nutrient composition for the late pregnancy, and the preparation method comprises the following steps:
s1, premixing
Mixing 50% of the crospovidone in parts by weight with the dextrin in parts by weight, and mixing with the microcrystalline cellulose in parts by weight by an equivalent incremental method; then uniformly mixing the raw materials with the parts by weight by an equivalent incremental method to prepare mixed powder;
s2, granulating and drying
The povidone K30 in parts by weight is dissolved in 60% ethanol to be used as a wetting agent, and the mixed powder is added for wetting to prepare a soft material; granulating by using a 18-mesh screen, flatly paving wet granules in a stainless steel plate, wherein the thickness of the wet granules cannot exceed 2 cm, drying by hot air circulation at the temperature of 40 ℃ until the moisture is 3-5%, and preparing dry granules;
s3, straightening granules
Collecting the dry granules, and grading the granules through a 16-mesh sieve to prepare granules after grading;
s4 Total mixing
Adding the rest of crospovidone into the granules after finishing granules, adding the magnesium stearate in the parts by weight, and performing total mixing operation to obtain a total mixed material;
s5, tabletting
Loading a punch die on a tablet press, adjusting the loading amount, pressure and rotating speed by using particles, and tabletting to obtain plain tablets, wherein the weight range of the tablets is controlled to be 0.97g +/-5%;
s6 coating
Taking the coating premix, and adding 50% ethanol to prepare a coating solution with the solid content of 10%; and (3) taking the plain tablets, putting the plain tablets into a coating machine, preheating the plain tablets, uniformly spraying a coating solution on the surfaces of the plain tablets, continuously blowing hot air at 40 ℃ for 5-10 minutes after the coating solution is sprayed, blowing cold air to the surfaces of the plain tablets to reach room temperature, taking out the coated tablets, and obtaining the coated tablets, wherein the coating weight is increased by 2.85-3.15%.
In addition, the invention also provides the application of the nutrient composition for the late pregnancy as a nutrient substance in the late pregnancy of the pregnant women. Specifically, the eating amount and the eating method are as follows: it is taken 2 times daily, 1 tablet each time, with warm water.
In the technical scheme, calcium carbonate, ferrous fumarate, zinc gluconate, selenium-enriched yeast, copper gluconate, retinyl acetate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, nicotinic acid, folic acid, L-ascorbic acid, VK1, D-calcium pantothenate and D-alpha-tocopherol are mixed scientifically, because:
the late pregnancy (28-40 weeks) is the comprehensive development period of the fetus, and in this period, all parts of the fetus, particularly the brain, develop rapidly, and at this time, besides enough calcium should be taken for the growth of the fetus, iron, copper, zinc, vitamins B6 and B12, etc. should be supplemented, so that the fetus can be healthily developed, and the problems of anemia and low body weight of the baby can be prevented.
Among the Chinese residents, dietary nutrient reference (DRI) indicates that: the standard supply of calcium for pregnant women in late pregnancy is 1200 mg/day. The late pregnancy fetus needs a large amount of calcium for bone growth and development, and the pregnant woman needs to supplement calcium in time when leg cramps appear. The pregnant woman in late pregnancy has increased calcium intake, and can improve the serum calcium level of newborn infant, and reduce and avoid the influence on infant development (height, weight, intelligence, bone density, etc.). The iron deficiency of pregnant women can cause congenital iron deficiency of newborn infants, directly influence the metabolism of fetal and newborn erythrocytes, cause the chronic hypoxia and growth and development disorder of fetal and newborn infants, and the iron deficiency is the main reason of the anemia of the pregnant women. The iron deficiency of the pregnant and late-stage mothers has obvious correlation with the iron deficiency anemia of the infants, and the supplement of the iron of the pregnant and late-stage mothers can prevent the iron deficiency anemia of the infants. Researches show that the combined calcium and zinc supplementation in the late pregnancy can effectively prevent the deficiency of blood calcium and zinc in the pregnancy. The zinc deficiency of the mother during pregnancy can affect the embryonic cell reproduction cycle, resulting in the slow development of the fetus and even the malformation of the fetus, and the maintenance of normal blood zinc concentration can improve the growth index of the newborn [10], and the zinc requirement of the fetus is the highest in the late pregnancy. The zinc supplement can improve the zinc concentration in the middle and late pregnancy of pregnant women, and is helpful for increasing the birth weight of newborn infants. The probability of preeclampsia of pregnant women with selenium deficiency in vivo is more than 4 times higher than that of other pregnant women, which is marked by hypertension, renal dysfunction and placental blood supply deficiency, so that the pregnant women have to pay attention to selenium supplement during pregnancy. The pregnant woman serum selenium is obviously lower than that of a non-pregnant woman along with the pregnant period, the selenium content in the newborn umbilical serum is low, the selenium content is probably a factor for generating low weight, and in order to meet the normal development of a fetus, attention is paid to supplement selenium for the pregnant woman. Pregnant women pay attention to ingest enough microelements such as calcium, magnesium, iron, zinc, copper and the like, and the pregnant women have certain positive significance for preventing abortion, dead fetus and premature rupture of fetal membranes.
The pregnant women lack VA in vivo, and the pregnant women can have nyctalopia, premature delivery and fetal malformation. The Yinle is found that the VA deficiency rate of the pregnant woman is high, and the serum retinol level of the pregnant woman in the late pregnancy period is in positive correlation with the VA dietary intake, the serum retinol level of the cord blood and the weight average of the newborn body. The VA nutrition level of the newborn is generally lower than that of the pregnant woman, and the retinol and beta-carotene levels of the newborn are related to the retinol level of the pregnant woman, so that the pregnant woman in late pregnancy needs to pay attention to the VA supplement. When VB1 is deficient, a human body feels violent, the body is easy to fatigue and weakness, edema of lower limbs, inappetence and other symptoms; in addition, the low level of VB1 is closely related to the occurrence of GDM. The VB2 and the iron preparation are combined to treat the IDA during pregnancy, the effect is obviously better than that of a pure iron supplement group, the side effect is low, and the clinical significance is obvious. The VB2 nutritional intervention can improve and maintain the nutritional level of iron in the pregnancy of the pregnant women, reduce the morbidity of anemia and iron deficiency rate in the pregnancy and has the function of promoting the absorption and utilization of iron. The intake of nicotinic acid in pregnant women is positively correlated with the level of cord blood adiponectin, and the level of adiponectin has influence on the growth and development of fetuses: the level of cord blood adiponectin is positively correlated with the birth weight and the birth length of the fetus. The folic acid supplemented to women of childbearing age can reduce fetal neural tube malformation such as cleft lip and palate, reduce pregnancy complications such as premature delivery, low-quality infants, induction of labor, dead fetus, and gestational hypertension, improve pregnancy fatality such as fetal distress and newborn asphyxia, and improve maternal-fetal prognosis. VC supplementation during pregnancy can prevent premature rupture of membranes, and can prevent preeclampsia to a certain extent. VK1 is routinely supplemented to pregnant women in late pregnancy to prevent neonatal hemorrhage. Pantothenic acid helps to form cells, maintain normal development and development of the central nervous system; preventing fatigue, relieving inappetence and nausea; has the function of producing antibodies, helps to fight infectious diseases, and helps to alleviate allergic symptoms. The lack of VE during pregnancy can lead to miscarriage, premature birth, preeclampsia, and fetal growth restriction. In addition, the enzyme has the functions of assisting proteolysis, promoting nutrient absorption and improving immunity, and is beneficial to the development and growth of fetuses.
The invention knows each stage of the fetus development, aims at the physiological characteristics and the nutritional requirements of pregnant women in the late pregnancy period, emphasizes the gold proportion of nutrition in each stage, provides microelements and vitamins such as calcium, iron, zinc, selenium, copper and the like required by the pregnant women in the late pregnancy period and the fetus, is beneficial to eliminating or lightening the pregnancy reaction in the late pregnancy period, improving the growth and development indexes of the fetus, preventing the birth defects of the fetus and other pregnancy fatalities of the fetus, is an ideal nutritional health food for the late pregnancy period, and fills the blank of the sectional development of the nutrients in the late pregnancy period at present.
Detailed Description
The invention relates to a nutrient composition for late pregnancy, which comprises the following components:
raw materials: calcium carbonate, ferrous fumarate, zinc gluconate, selenium-enriched yeast, copper gluconate, retinyl acetate, thiamine hydrochloride, riboflavin, pyridoxine hydrochloride, nicotinic acid, folic acid, L-ascorbic acid, vitamin K1, D-calcium pantothenate, and D-alpha-tocopherol;
auxiliary materials: microcrystalline cellulose, crospovidone, povidone K30, sodium starch octenylsuccinate, dextrin, maltodextrin, magnesium stearate, sucrose, edible corn starch, acacia, tricalcium phosphate, dl-alpha-tocopherol, silicon dioxide, coating premixes (hydroxypropyl methylcellulose, polyethylene glycol 6000, glycerol, talc, titanium dioxide, yellow iron oxide).
The raw materials and auxiliary materials are processed by main processes of mixing, granulating, drying, finishing, total mixing, tabletting, coating, aluminum-aluminum packaging, external packaging and the like.
The quality requirements of raw materials and auxiliary materials are as follows:
1. calcium carbonate: the calcium carbonate injection should meet the corresponding regulations of GB1886.214 calcium carbonate (including light calcium carbonate and heavy calcium carbonate).
2. Selenium-rich yeast: the product should meet the corresponding regulation of national drug standard WS1- (x-005) -99Z selenium Yeast.
3. Ferrous fumarate: it should meet the corresponding regulations of ferrous fumarate in the second part of the Chinese pharmacopoeia (2015 edition).
4. Zinc gluconate: the regulation should meet the corresponding regulation of GB8820 zinc gluconate.
5. Retinyl acetate: the vitamin D should meet the corresponding regulation of GB14750 vitamin A.
6. Thiamine hydrochloride: the compound should meet the corresponding regulations of GB14751 vitamin B1 (thiamine hydrochloride).
7. Riboflavin: the vitamin D-vitamin E should meet the corresponding regulations in GB14752 vitamin B2 (riboflavin).
8. Pyridoxine hydrochloride: it should meet the corresponding regulations of GB14753 vitamin B6 (pyridoxine hydrochloride).
9. Nicotinic acid: the corresponding regulation of GB14757 Niacin should be met.
10. Folic acid: the corresponding regulation of GB15570 Folic acid is met.
11. Vitamin C (L-ascorbic acid): it should meet the corresponding regulations of GB14754 vitamin C (ascorbic acid).
Calcium D-pantothenate: it should meet the corresponding regulations of calcium pantothenate in the second part of the Chinese pharmacopoeia (2015 edition).
13. Microcrystalline cellulose: the product meets the corresponding regulation of GB1886.103 food safety national standard food additive microcrystalline cellulose.
14. Cross-linked povidone: it should meet the corresponding regulations of the four parts of the Chinese pharmacopoeia (2015 edition) of crospovidone.
15. Povidone K30: it should meet the corresponding regulations of "Povidone K30" in the four parts of the Chinese pharmacopoeia (2015 edition).
16. Maltodextrin, 2: the corresponding regulation of GB/T20884 maltodextrin should be met.
17. Dextrin: it should meet the requirements of dextrin in the four parts of Chinese pharmacopoeia (2015 edition).
18. Magnesium stearate: the magnesium stearate powder should meet the corresponding regulations of GB1886.91 magnesium stearate.
19. Sucrose: it should conform to the corresponding regulation of sucrose in the four parts of the Chinese pharmacopoeia (2015 edition).
20. Edible corn starch: the product meets the corresponding regulation of GB/T8885 edible corn starch.
21. Gum arabic: the gum meets the corresponding regulation of GB29949 national standard for food safety, namely acacia.
Dl- α -tocopherol: the vitamin E (dl-alpha-tocopherol) vitamin E injection should meet the corresponding regulations of GB29942 national standard for food safety.
23. Tricalcium phosphate: the product is in accordance with the corresponding regulation of GB25558, national food safety standard, tricalcium phosphate.
24. Copper gluconate: the method meets the corresponding regulation of GB1903.8 copper gluconate.
25. Vitamin K1: it should meet the corresponding regulations of "vitamin K1" in the second part of Chinese pharmacopoeia (2015 edition).
D- α -tocopherol: the vitamin E should meet the corresponding regulation of GB1886.233 vitamin E.
27. Sodium starch octenylsuccinate: the product is in accordance with the corresponding regulation of GB28303 food safety national standard food additive sodium octenyl succinate starch.
28. Silicon dioxide: the product is in accordance with the corresponding regulation of GB25576 national food safety standard silicon dioxide.
The medicinal aluminum foil conforms to the medicinal aluminum foil (YBB 00152002-2015); the polyamide/aluminum/polyvinyl chloride cold stamping solid medicinal composite hard sheet meets the requirements of polyamide/aluminum/polyvinyl chloride cold stamping solid medicinal composite hard sheet (YBB 00242002-2015).
The present invention will be described in further detail with reference to examples.
EXAMPLE 1 preparation of a nutrient composition for late pregnancy
The nutrient composition for the late pregnancy comprises the following raw and auxiliary materials:
wherein the coating premix is prepared by mixing hydroxypropyl methylcellulose, polyethylene glycol 6000, glycerol, talcum powder, titanium dioxide and yellow ferric oxide by a conventional method.
A method of preparing a late pregnancy nutrient composition comprising the steps of:
1 premixing
Mixing the 50% of crospovidone with dextrin; mixing with microcrystalline cellulose by equivalent incremental method; and then uniformly mixing the powder with the premixed raw materials by an equivalent incremental method to prepare mixed powder.
2 granulating and drying
Dissolving polyvidone K30 in 60% ethanol to obtain wetting agent, adding the mixed powder, and making into soft material; granulating by using a 18-mesh screen, paving wet granules in a stainless steel plate, drying at 40 ℃ until the moisture content is 3-5% by drying in a hot air circulation manner, and thus obtaining dry granules, wherein the thickness of the wet granules cannot exceed 2 cm.
3 finishing of granules
Collecting the dry granules, and grading with 16 mesh sieve to obtain granules.
4 Total mixing
And adding the rest of crospovidone into the granules after finishing the granules, adding magnesium stearate, and performing total mixing operation to obtain a total mixed material.
5 tabletting
Loading a punch die on a tablet press, adjusting the loading amount, pressure and rotating speed by using particles, and tabletting for 1000 tablets (1.0 g/tablet), wherein the weight range of the tablets is controlled to be 0.97g +/-5 percent, so that the plain tablets are obtained. During the tabletting process, the operator checks the tablet weight every 15 minutes.
6 coating
And adding 50% ethanol into the coating premix to prepare a coating solution with the solid content of 10%. And (3) taking plain tablets, putting the plain tablets into a coating machine, starting the coating machine, preheating the plain tablets, then starting an exhaust fan and a spraying system, uniformly spraying coating liquid on the surfaces of the plain tablets, continuously blowing hot air at 40 ℃ for 5-10 minutes after the coating liquid is sprayed, then blowing cold air until the surfaces of the plain tablets reach room temperature, and taking out the coated tablets to obtain the coated tablets. The weight of the coating is increased by about 3 percent.
7 inner package
And (4) taking the inner packing material of the aluminum-aluminum package, debugging an inner packing machine, and carrying out aluminum-aluminum packaging according to 5 sheets/plate.
8 external packing
And taking the materials for external packaging such as product specifications, packaging boxes and the like, and carrying out external packaging to obtain the finished product.
9 inspection and warehousing
Sampling, checking and issuing a check report. And (4) handling warehousing procedures according to qualified inspection reports.
10 process requirements
The feeding to the inner package are all carried out in a 10 ten thousand grade clean area, and the outer package is carried out in a general production area.
EXAMPLE 2 preparation of a nutrient composition for late pregnancy
2g of oxidoreductase (SOD), 1g of protease and the following other raw and auxiliary materials are adopted as the ferment:
the preparation method is the same as that of example 1.
EXAMPLE 3 preparation of a nutrient composition for late pregnancy
The enzyme adopts 5g of protease, and other raw and auxiliary materials are as follows:
the preparation method is the same as that of example 1.
EXAMPLE 4 Final product quality testing
Two panels of the finished package prepared in examples 1-3 were randomly picked, one panel sample was inspected at all, and the other panel was sealed and stored for future reference. Wherein, the sensory requirement accords with the requirement of table 1, the physical and chemical index accords with the requirement of table 2, the microorganism index accords with the requirement of table 3, and the content measurement of the functional components accords with the requirement of table 4. The detection results of the products all meet the requirements.
TABLE 1 sensory requirements
| Item | Require that | Detection method |
| Color and luster | Coating is light yellow, core is light yellow or pink | Visual inspection of |
| Taste and smell | Has special taste and smell of the product, and has no peculiar smell | Smelling and tasting the nose |
| Status of state | Film-coated tablets, complete and smooth; foreign body visible without normal vision | Visual inspection of |
TABLE 2 physical and chemical indexes
| Item | Index (I) | Detection method |
| Ash content% | ≤65.0 | GB5009.4 |
| Lead (Pb), mg/kg | ≤2.0 | GB5009.12 |
| Total arsenic (As), mg/kg | ≤1.0 | GB5009.11 |
| Total mercury (Hg), mg/kg | ≤0.3 | GB5009.17 |
| Disintegration time limit, min | ≤60 | Pharmacopoeia of the people's republic of China 2015 edition four parts |
TABLE 3 microbiological indicators
| Item | Index (I) | Detection method |
| Total number of colonies, CFU/g | ≤30000 | GB4789.2 |
| Coliform group, MPN/g | ≤0.92 | GB4789.3MPN counting method |
| Mold and Yeast, CFU/g | ≤50 | GB4789.15 |
| Staphylococcus aureus | ≤0/25g | GB4789.10 |
| Salmonella | ≤0/25g | GB4789.4 |
TABLE 4 index of effective components
While embodiments of the invention have been disclosed above, it is not intended to be limited to the uses set forth in the specification and examples. It can be applied to all kinds of fields suitable for the present invention. Additional modifications will readily occur to those skilled in the art. Therefore, the invention is not to be limited to the specific details and embodiments shown and described herein, without departing from the general concept defined by the appended claims and their equivalents.
Claims (9)
1. The nutrient composition for the pregnant women and the later-period is characterized by comprising the following raw materials in parts by weight:
2. the nutrient composition for pregnant women and later period as claimed in claim 1, which comprises the following raw materials by weight:
3. the nutrient composition according to claim 1 or 2, wherein the raw material further comprises 0-5 parts by weight of enzyme.
4. The late pregnancy nutrient composition of claim 3, wherein the enzyme is one or both of a protease and an oxidoreductase.
5. The nutrient composition of claim 4, wherein the nutrient composition is mixed with pharmaceutically acceptable excipients and made into tablets, granules or capsules.
6. The nutrient composition for pregnant women and later period as claimed in claim 5, wherein the nutrient composition is mixed with the following auxiliary materials in parts by weight to prepare tablets:
7. the nutrient composition for pregnant women and later period as claimed in claim 6, wherein the nutrient composition is mixed with the following auxiliary materials in parts by weight to prepare tablets:
8. the late pregnancy nutrient composition of claim 6 or 7, which is prepared by a process comprising the steps of:
s1, premixing
Mixing 50% of the crospovidone in parts by weight with the dextrin in parts by weight, and mixing with the microcrystalline cellulose in parts by weight by an equivalent incremental method; then uniformly mixing the raw materials with the parts by weight by an equivalent incremental method to prepare mixed powder;
s2, granulating and drying
The povidone K30 in parts by weight is dissolved in 60% ethanol to be used as a wetting agent, and the mixed powder is added for wetting to prepare a soft material; granulating by using a 18-mesh screen, flatly paving wet granules in a stainless steel plate, wherein the thickness of the wet granules cannot exceed 2 cm, drying by hot air circulation at the temperature of 40 ℃ until the moisture is 3-5%, and preparing dry granules;
s3, straightening granules
Collecting the dry granules, and grading the granules through a 16-mesh sieve to prepare granules after grading;
s4 Total mixing
Adding the rest of crospovidone into the granules after finishing granules, adding the magnesium stearate in the parts by weight, and performing total mixing operation to obtain a total mixed material;
s5, tabletting
Loading a punch die on a tablet press, adjusting the loading amount, pressure and rotating speed by using particles, and tabletting to obtain plain tablets, wherein the weight range of the tablets is controlled to be 0.97g +/-5%;
s6 coating
Taking the coating premix, and adding 50% ethanol to prepare a coating solution with the solid content of 10%; and (3) taking the plain tablets, putting the plain tablets into a coating machine, preheating the plain tablets, uniformly spraying a coating solution on the surfaces of the plain tablets, continuously blowing hot air at 40 ℃ for 5-10 minutes after the coating solution is sprayed, blowing cold air to the surfaces of the plain tablets to reach room temperature, taking out the coated tablets, and obtaining the coated tablets, wherein the coating weight is increased by 2.85-3.15%.
9. Use of the late pregnancy nutrient composition according to any one of claims 1-7 as a nutritional substance for the late pregnancy of a pregnant woman.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911218720.4A CN110720632A (en) | 2019-12-03 | 2019-12-03 | Nutrient composition for late pregnancy and preparation method and application thereof |
Applications Claiming Priority (1)
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