Disclosure of Invention
The invention aims to solve the technical problem of providing a reaction cup grabbing and placing device for an immunoassay analyzer aiming at the defects in the prior art.
In order to solve the technical problems, the invention adopts the following technical scheme: a cuvette handling device for an immunoassay analyzer, comprising: the reaction cup, the clamping jaw mechanism used for grabbing the reaction cup and the two-dimensional translation mechanism used for driving the clamping jaw mechanism to move;
the clamping jaw mechanism comprises a mounting seat, clamping jaws arranged on the mounting seat and a stop block;
The clamping jaw comprises two symmetrical half clamping jaws which are rotatably arranged on the mounting seat, a clamping cavity for clamping the reaction cup is formed between the first ends of the two half clamping jaws, and a compression spring is connected between the second ends of the two half clamping jaws; and the stop block is provided with a limit groove, and the second ends of the two half clamping jaws are arranged in the limit groove.
Preferably, the first end of the half clamping jaw is provided with a clamping arm, the inner side of the clamping arm is provided with an arc clamping groove, and when the clamping parts of the two half clamping jaws are closed, the arc clamping grooves on the inner sides of the clamping arms form the clamping cavity.
Preferably, a guiding inclined plane is arranged at the inlet of the clamping arm.
Preferably, an inclined surface is arranged on the inner side of the second end of the half clamping jaw;
And a blind hole for setting the compression spring is formed in the inclined surface of the inner side of the second end of the half clamping jaw.
Preferably, the lower surface of the half clamping jaw is provided with a groove, and the upper surface of the half clamping jaw is provided with a rotating shaft hole penetrating to the groove;
two mounting holes are formed in the mounting seat; a rotating shaft extending into the mounting hole is inserted into the rotating shaft hole from bottom to top;
the upper end of the rotating shaft extends out of the periphery of the mounting hole to form an annular clamping groove, and the annular clamping groove is provided with a clamp spring; the lower end of the rotating shaft is accommodated in the groove.
Preferably, the reaction cup comprises a cup head and a cup body connected to the lower portion of the cup head, flanges are arranged on the upper portions of the cup head and the cup body, and a cylindrical clamping portion is formed between the two flanges.
Preferably, a guide post is arranged on the upper surface of the second end of the half clamping jaw, and 2 arc-shaped guide grooves for respectively matching and inserting the 2 guide posts of the 2 half clamping jaws are arranged on the inner wall of the upper part of the limit groove;
The arrangement track of the arc-shaped guide groove is consistent with the track of the guide post movement when the half clamping jaw rotates.
Preferably, the guide post comprises a column part connected with the upper surface of the half clamping jaw and a sphere part connected to the column part, and the sphere part is slidably arranged in the arc-shaped guide groove.
Preferably, a buffer spring is connected between the outer side of the second end of the half clamping jaw and the inner side wall of the limit groove on the stop block.
Preferably, a polytetrafluoroethylene layer is arranged on the inner wall of the arc-shaped guide groove; and a soft adhesive layer is arranged on the inner wall of the arc-shaped clamping groove.
The beneficial effects of the invention are as follows:
1) The clamping jaw mechanism realizes the grabbing and clamping of the reaction cup by using the spring device, has compact and small structure, does not have a driving device and does not need a special control system; after the two-dimensional motion mechanism is matched with the two-dimensional motion mechanism, only the two-dimensional motion mechanism is required to be controlled, and the control is simple.
2) The clamping force can be changed by adjusting the stiffness coefficient of the compression spring, so that the small impact in the clamping process can be ensured.
3) The clamping jaw clamps from the side edge of the reaction cup, is not inserted into the reaction cup and is not contacted with the cup rim, so that cross contamination between samples is avoided.
4) The invention has simple structure and high reliability.
Drawings
FIG. 1 is a schematic diagram of a cuvette handling and placing apparatus for an immunoassay analyzer according to the present invention;
FIG. 2 is a schematic view of a jaw mechanism of the present invention;
FIG. 3 is a schematic view of the back view of the jaw mechanism of the present invention;
FIG. 4 is a schematic view of the structure of the jaw mechanism of the present invention from the bottom perspective;
FIG. 5 is a schematic diagram of a semi-jaw structure in an embodiment of the invention;
FIG. 6 is a schematic view of a spindle according to the present invention;
FIG. 7 is a schematic view of the structure of the invention with the spindle engaged with the jaw mechanism;
FIG. 8 is a schematic structural view of a reaction cup according to the present invention;
FIG. 9 is a schematic view of a semi-jaw structure in another embodiment of the invention;
FIG. 10 is a schematic view of a block in an embodiment of the invention;
FIG. 11 is a schematic diagram showing the cooperation of the half-jaw and the stopper according to an embodiment of the present invention.
Reference numerals illustrate:
1-a clamping jaw mechanism; 10, an installation seat; 11-clamping jaw; 12-a stop block; 13-a clamping cavity; 14-compressing the spring; 15-a rotating shaft; 16-a guide post; 17-a buffer spring; 100-mounting holes; 110—a half jaw; 111-a clamping arm; 112-arc clamping groove; 113-a guiding ramp; 114-inclined plane; 115-blind holes; 116-groove; 117-a spindle bore; 118-spring groove; 120-a limit groove; 121-an arc-shaped guide groove; 150-an annular clamping groove; 151-clamping springs; 160-column section; 161-sphere;
2-a two-dimensional translation mechanism; a 20-X axis motor screw rod mechanism; 21-Z axis motor screw rod mechanism; 22-mounting plate; 23-Z axis guide rail; 24-Z axis motor; 25-Z axis sliding block;
3-a reaction cup; 30-cup head; 31-a cup body; 32-a flange; 33—a clamping portion; 34-protrusions.
Detailed Description
The present invention is described in further detail below with reference to examples to enable those skilled in the art to practice the same by referring to the description.
It will be understood that terms, such as "having," "including," and "comprising," as used herein, do not preclude the presence or addition of one or more other elements or groups thereof.
As shown in fig. 1 to 8, a cuvette handling device for an immunoassay analyzer of the present embodiment includes: the reaction cup 3, a clamping jaw mechanism 1 for grabbing the reaction cup 3 and a two-dimensional translation mechanism 2 for driving the clamping jaw mechanism 1 to move;
the clamping jaw mechanism 1 comprises a mounting seat 10, clamping jaws 11 arranged on the mounting seat 10 and a stop block 12;
The clamping jaw 11 comprises two symmetrical half clamping jaws 110 which are rotatably arranged on the mounting seat 10, a clamping cavity 13 for clamping the reaction cup 3 is formed between the first ends of the two half clamping jaws 110, and a compression spring 14 is connected between the second ends of the two half clamping jaws 110;
the stop block 12 is provided with a limit groove 120, and the second ends of the two half clamping jaws 110 are arranged in the limit groove 120.
The invention can be mainly applied to an immunoassay analyzer for grasping and placing the reaction cup 3 so as to transport the reaction cup 3 to a designated operation position. The two-dimensional translation mechanism 2 can adopt a motor screw rod mechanism or a belt pulley driving mechanism and the like for driving the clamping jaw mechanism 1 to perform two-dimensional motion, the clamping jaw mechanism 1 is unpowered, and grabbing and placing of the reaction book are realized by means of driving of the compression spring 14 and the two-dimensional translation mechanism 2.
In this embodiment, referring to fig. 2-7, a first end of the half clamping jaw 110 is provided with a clamping arm 111, an inner side of the clamping arm 111 is provided with an arc clamping groove 112, and when the clamping portions 33 of the two half clamping jaws 110 are closed, the arc clamping grooves 112 on the inner sides of the two clamping arms 111 form a clamping cavity 13. The entrance of the clamping arm 111 is provided with a guiding slope 113 guiding the cuvette 3 into the clamping chamber 13. The inner sides of the second ends of the half clamping jaws 110 are provided with inclined surfaces 114, so that a V-shaped groove is formed in the middle of the second ends of the two half clamping jaws 110, and the two half clamping jaws 110 can rotate to realize closing and opening. The inclined surface 114 on the inner side of the second end of the half jaw 110 is provided with a blind hole 115 for arranging the compression spring 14, and the compression spring 14 is compressed after being mounted to generate a reaction force. A groove 116 is formed in the lower surface of the half clamping jaw 110, and a rotating shaft hole 117 penetrating through the groove 116 is formed in the upper surface of the half clamping jaw 110; two mounting holes 100 are formed in the mounting seat 10; a rotating shaft 15 extending into the mounting hole 100 is inserted into the rotating shaft hole 117 from bottom to top; the upper end of the rotating shaft 15 extends out of the periphery of the mounting hole 100 to form an annular clamping groove 150, and the annular clamping groove 150 is provided with a clamping spring 151; the lower end of the rotary shaft 15 is accommodated in the recess 116. Ensuring the lower surface of the clamping jaw 11 to be flat and avoiding collision with other mechanisms during movement.
The rotating shaft 15 is inserted into the mounting hole 100 from bottom to top through the rotating shaft hole 117, the clamping spring 151 is sleeved on the annular clamping groove 150 and is positioned on the upper surface of the mounting seat 10, and the axial movement of the rotating shaft 15 is limited, so that the half clamping jaw 110 can be rotatably connected to the mounting seat 10.
Referring to fig. 8, the reaction cup 3 includes a cup head 30 and a cup body 31 connected to a lower portion of the cup head 30, wherein flanges 32 are provided on upper portions of the cup head 30 and the cup body 31, and a cylindrical clamping portion 33 is formed between the two flanges 32. In a further embodiment, the side walls of the cup 31 are planar. After the reaction of the sample in the reaction cup 3 and the reagent is completed, the measuring probe of the instrument can be tightly attached to the side wall of the reaction cup 3 for measurement, and the luminous signal loss in the reaction cup 3 caused by the imprecise attachment can be avoided. The upper part of the cup 31 is provided with 4 protrusions 34 for positioning the cuvette 3 in the instrument. The mouth of the reaction cup 3 is rectangular, 2 liquid suction needles can be inserted simultaneously, and the liquid suction needles cannot contact with the wall of the cup and scratch. Meanwhile, 2 liquid suction needles are inserted, so that the two works of liquid suction and filling of the reaction cup 3 can be completed at one station, and the instrument efficiency is effectively improved.
The process of holding and placing the reaction cup 3 by the clamping jaw mechanism 1 is as follows: the two-dimensional translation mechanism 2 drives the clamping jaw mechanism 1 to horizontally move to be close to the reaction cup 3, when the clamping jaw 11 contacts the reaction cup 3, the guide inclined plane 113 at the inlet of the clamping jaw 11 is tangent to the cylindrical clamping part 33 of the reaction cup 3, the clamping part 33 extrudes the two half clamping jaws 110, the elasticity of the compression spring 14 is overcome, and the half clamping jaws 110 are gradually pushed away by the reaction cup 3; when the arc of the inside of the clamping part 33 of the cuvette 3 and the clamping jaw 11 coincide (the clamping part 33 enters the clamping chamber 13), the cuvette 3 is clamped in place. The two-dimensional mechanism then transfers the cuvette 3 to the designated location as required by the instrument. After the reaction cup 3 is fixed at the designated position, the two-dimensional mechanism drives the clamping jaw mechanism 1 to move in the opposite direction of the clamping process, and the clamping jaw 11 is opened by extrusion of the clamping part 33, so that the reaction cup 3 is automatically separated from the clamping jaw 11.
The clamping jaw mechanism 1 is unpowered, and the clamping jaw mechanism 1 and the reaction cup 3 can be grabbed and placed by means of the relative movement between the two-dimensional translation mechanism 2. The two half jaws 110 are expanded at the second end (tail) by the compression spring 14, and the first end (front) is retracted to tighten the cuvette 3 through the first end. Under the action of the compression spring 14, the tail portion is excessively opened, and the jaw 11 swings left and right. In order to avoid this, a stop block 12 is provided on the mounting base 10, a limit groove 120 is provided on the stop block 12, and the second ends of the two half clamping jaws 110 are clamped therein, so that a certain range of rotation can be performed, but the positions are limited, and the two half clamping jaws cannot be excessively opened. The clamping force can be changed by adjusting the stiffness coefficient of the compression spring 14, so that the impact of the clamping process is small.
Wherein the thickness of the clamping jaw 11 at the inlet is smaller than the height of the clamping part 33 of the reaction cup 3. When clamping the reaction cup 3, a certain redundancy exists, and the clamping jaw 11 is prevented from entering the clamping part 33 due to the deviation of the movement height of the clamping jaw 11.
In this embodiment, the two-dimensional translation mechanism 2 adopts two motor screw mechanisms, and referring to fig. 1, includes an X-axis motor screw mechanism 20 and a Z-axis motor screw mechanism 21. The two sets of drive mechanisms are similar in structure and are illustrated by way of example as a Z-axis motor lead screw mechanism 21. The Z-axis motor screw mechanism 21 comprises a mounting plate 22 arranged on the X-axis motor screw mechanism 20, a Z-axis guide rail 23 fixedly connected to the mounting plate 22, a Z-axis motor 24 fixedly connected to the mounting plate 22, a screw rod (not shown in the figure) in driving connection with the Z-axis motor 24, and a Z-axis sliding block 25 slidably arranged on the Z-axis guide rail 23 and in threaded fit with the screw rod. The clamping jaw mechanism 1 is connected to the Z-axis sliding block 25, the X-axis motor screw rod mechanism 20 drives the Z-axis motor screw rod mechanism 21 to horizontally move along the X-axis integrally, and the Z-axis motor 24 drives the Z-axis sliding block 25 to vertically move along the Z-axis direction through the screw rod, so that the two-dimensional movement of the clamping jaw mechanism 1 in the X, Z-axis direction is realized. The X-axis motor screw rod mechanism 20 also comprises a motor, a screw rod and a sliding block, wherein the mounting plate 22 is arranged on the sliding block, and the motor drives the sliding block to move along the X axis through the screw rod, so that the Z-axis motor screw rod mechanism 21 on the mounting plate 22 is driven to move along the X axis.
In a further preferred embodiment, referring to fig. 9 to 11, the upper surface of the second end of the half clamping jaw 110 is provided with a guide post 16, and the upper inner wall of the limit groove 120 is provided with 2 arc-shaped guide grooves 121 for respectively inserting the 2 guide posts 16 of the 2 half clamping jaws 110 in a matched manner; the arcuate guide slot 121 is positioned to follow the path of movement of the guide post 16 as the semi-jaw 110 rotates. The guide post 16 includes a column portion 160 coupled to the upper surface of the half jaw 110, and a ball portion 161 coupled to the column portion 160, the ball portion 161 being slidably disposed in the arc-shaped guide groove 121. A buffer spring 17 is connected between the outer side of the second end of the half clamping jaw 110 and the inner side wall of the limit groove 120 on the stop block 12, a spring groove 118 is arranged on the outer side of the second end of the half clamping jaw 110, and one end of the buffer spring 17 is fixedly connected in the spring groove 118. The spring force of the buffer spring 17 is smaller than that of the compression spring 14, and the buffer effect thereof.
After long-term use, when the half clamping jaw 110 is rotated by the compression spring 14 or external force, the two half clamping jaws 110 may shake or swing left and right due to uneven stress or loose rotation of the rotating shaft 15, so that the rotation track of the two half clamping jaws 110 is asymmetric (for example, the rotation track expands outwards while expands outwards to be small, so that the clamping cavity 13 deforms, and the middle line of the clamping cavity deviates to influence the alignment with the middle line of the reaction cup 3), and the grasping firmness of the reaction is affected. The above-described problem is solved in the present embodiment by providing the arc-shaped guide groove 121 and the guide post 16. The two half clamping jaws 110 are forced to rotate, and the guide posts 16 are limited to slide in the arc-shaped guide grooves 121, so that the rotation tracks of the two half clamping jaws 110 are limited, the rotation tracks of the two half clamping jaws 110 are symmetrical, the shaking or left-right swinging of the half clamping jaws 110 can be greatly reduced, and the clamping effect on the reaction cup 3 is ensured. In addition, for example, when the reaction cup 3 is separated from the clamping jaw 11, the rear ends of the two half clamping jaws 110 are compressed and contracted to be expanded under the action of the elasticity of the compression spring 14, the outer walls of the second ends of the two half clamping jaws 110 are easy to collide with the inner side walls of the limiting grooves 120 and are easy to damage, and shaking and noise of the mechanism can be generated.
In a still further preferred embodiment, the inner walls of the arcuate guide slots 121 are provided with a polytetrafluoroethylene layer which reduces friction and facilitates sliding of the guide posts 16 therein; and the wear resistance can be enhanced, and the service life can be prolonged. The inner wall of the arc-shaped clamping groove 112 is provided with a soft adhesive layer, and the soft adhesive layer can be made of silica gel or rubber, so that the friction force between the soft adhesive layer and the reaction cup 3 can be increased, and the reaction cup 3 can be protected.
In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc. indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings are merely for convenience in describing the present invention and simplifying the description, and do not indicate or imply that the device or element being referred to must have a specific orientation, be configured and operated in a specific orientation, and therefore should not be construed as limiting the present invention.
Although embodiments of the present invention have been disclosed above, it is not limited to the use of the description and embodiments, it is well suited to various fields of use for the invention, and further modifications may be readily apparent to those skilled in the art, and accordingly, the invention is not limited to the particular details without departing from the general concepts defined in the claims and the equivalents thereof.