CN110470524A - A kind of pathology slide dyeing apparatus and colouring method - Google Patents

Abstract

The invention discloses a pathological glass slide staining device and a staining method, comprising a support frame, a rotating drive device arranged on the support frame, a slide mounting frame, a cavity barrel and a lifting device arranged under the slide mounting frame; The cavity barrel is connected with the lifting device; or the slide mounting frame is connected with the rotating drive device, and the rotating drive device is installed on the support frame through the lifting device; the lifting device can drive the rotating drive device or the cavity barrel to move up and down, and the slide is installed The frame extends into or moves out of the cavity of the cavity barrel body, and the slide mounting frame can be rotated under the drive of the rotary driving device. Put the dye in the cavity barrel, extend the slide mounting frame with pathological slides into the cavity barrel, and the rotating drive device drives the slide mounting frame to rotate, so that the pathological slides and the dye are in quick contact with the dye, and the contact is uniform. Therefore, the pathological slide staining device of the present application has high staining efficiency and good staining uniformity for pathological slides.

Description

A kind of pathological slide staining device and staining method

technical field

The invention relates to the technical field of medical appliances, in particular to a pathological slide staining device and a staining method.

Background technique

At present, during the staining process of the pathological slides, it is necessary to place the pathological slides on a staining rack and then put the staining rack into a staining vat for staining. However, the existing staining racks for pathological slides are easy to be knocked over during use, and in the staining vat, people need to shake the staining racks by hand to make the slides stain evenly, and then drain the staining solution before entering the next vat of staining solution , the staining efficiency is low, and the uniformity of slide staining is poor. In addition, since the staining of the pathological slides needs to go through multiple processes, the staining of the slides can be made even by shaking with hands, and the long-term operation will make people tired. Therefore, there is an urgent need for a pathological slide staining device that improves the staining efficiency and staining quality of pathological slides.

Contents of the invention

The object of the present invention is to overcome at least one deficiency of the above-mentioned prior art, and provide a pathological slide staining device that improves the staining efficiency and quality of pathological slides. In addition, a method for staining pathological glass slides is also provided.

The technical solution of the present invention to solve the above-mentioned technical problems is as follows: a pathological glass slide staining device, including a support frame, a rotating drive device arranged on the support frame, a slide mounting frame for installing the pathological slide, a device A cavity barrel and a lifting device below the slide mounting rack;

The cavity barrel is connected with the lifting device;

Or the slide mounting frame is connected to the rotary drive device, and the rotary drive device is installed on the support frame through a lifting device;

The lifting device can drive the rotary drive device or the cavity barrel to move up and down, and the slide mounting frame extends into the cavity of the cavity barrel or moves out of the cavity of the cavity barrel , and the slide mounting frame can be rotated under the drive of the rotary drive device.

The beneficial effect of the present invention is: by putting the dye into the cavity barrel body in the pathological glass slide staining device of the present invention, the cavity barrel body or the slide mounting frame can move up and down under the action of the lifting device, thereby realizing glass slide staining. The slide mounting frame extends into the cavity of the cavity barrel body, which is convenient to install the pathological slides on the slide mounting frame and extend it into the cavity of the cavity barrel body, and the rotary drive device is turned on to install the slides. The frame can be rotated under the drive of the rotary drive device, which is conducive to the rapid contact between the pathological slide and the dye during the staining process, and the contact is uniform, the staining efficiency is high, and the dyeing uniformity is good; the pathological slide is stained, and the slide is installed The frame is removed from the cavity of the cavity barrel, and the next process can be entered.

In addition, on the basis of the above technical solutions, the present invention can also be improved as follows, and can also have the following additional technical features.

According to an embodiment of the present invention, there are a plurality of hollow barrels, the plurality of hollow barrels are arranged at intervals along the length direction of the support frame, and the plurality of hollow barrels are respectively described The lifting device is connected; the rotary drive device is slidably installed on the support frame, and can move horizontally along the length direction of the support frame to the top of any one of the cavity barrels. By arranging a plurality of cavity barrels at intervals along the length direction of the support frame, it is beneficial to arrange a plurality of cavity barrels at intervals along the length direction of the support frame, which is beneficial to different cavities respectively. Dye, dewaxing agent, dehydrating agent and cleaning solution are added to the barrel, and the hollow barrel can also be directly used as a draining barrel; in addition, the rotary drive device is slidably installed on the support frame, and can be The length direction horizontally moves to the top of a plurality of the cavity barrels, so that the slide mounting frame with pathological slides is moved to the top of the cavity barrels of different staining processes, and then the slide mounting frame is extended by the lifting device. into the cavity barrel for corresponding staining treatment, and then move the lifting device to move the slide mounting frame out of the cavity of the cavity barrel and enter the next process; thus move the rotating drive device in turn and carry out the staining process on the slide Staining treatment, through multiple processes, completes the staining of slides, and the operation is more convenient.

According to one embodiment of the present invention, the slide mounting rack includes a top plate and a bottom plate, the top plate is connected to the rotary drive device, the bottom plate is connected to the lower end of the top plate through a connecting shaft, and the lower side of the top plate Corresponding to the upper side of the bottom plate, there are a plurality of installation grooves for installing the pathological glass slides. By providing a plurality of installation grooves for installing the pathological slides on the slide mounting frame, it is convenient to install a plurality of pathological slides, it is beneficial to install more pathological slides, and it is beneficial to improve the staining efficiency of the pathological slides .

According to an embodiment of the present invention, both the top plate and the bottom plate have a cylindrical structure, the connecting shaft is connected at the central position of the top plate and the bottom plate, and a plurality of the installation grooves are arranged circumferentially along the connecting shaft, each The two installation grooves respectively extend to the peripheral edge along the radial direction of the top plate or the bottom plate, and several pathological glass slides can be installed between the upper and lower opposite installation grooves in the top plate and the bottom plate . By arranging a plurality of installation grooves along the circumferential direction of the connecting shaft, it is convenient to install pathological slides. In addition, a number of pathological slides can be installed between every two oppositely opened mounting grooves, which is conducive to installing more pathological slides on the slide mounting rack, and is conducive to improving the The number of pathological slides stained in a single session.

According to an embodiment of the present invention, the slide mounting rack further includes a clamping block, the lower side of the top plate and the upper side edge of the bottom plate are provided with clamping grooves, and the clamping grooves are staggered and communicated with the mounting grooves, The clamping block is adapted to be clamped in the clamping slot and is located on the outside of the pathological glass slide installed in the mounting slot. The lower side of the top plate and the edge of the upper side of the bottom plate are provided with draw-in slots, and are fitted and snapped into the draw-in slots with clamping blocks, thereby limiting the pathological glass slides installed in the installation slots, preventing the During the rotation process of the slide mounting rack, the pathological slides are detached from the mounting groove to the outside.

According to an embodiment of the present invention, the rotary drive device is a variable speed drive motor, and the slide mounting frame is installed on an output shaft of the variable speed drive motor. Using a variable-speed drive motor as the rotary drive device is beneficial to adjust the rotation of the slide mounting frame by adjusting the speed of the variable-speed drive motor, which can make the pathological slide staining device have multiple speeds to meet the needs of different staining speeds. Improve the uniformity of dyeing.

According to an embodiment of the present invention, the support frame includes a pair of parallel and horizontal support rails, the rotation driving device is slidably mounted on the support rails, and can move along the length direction of the support rails. By providing a pair of parallel and horizontally arranged support guide rails on the support frame, it is beneficial for the rotary driving device to move horizontally on the support guide rails to the top of the plurality of cavity barrels sequentially and perform different dyeing processes.

According to an embodiment of the present invention, the pathological glass slide staining device further includes a slide plate, the two ends of the slide plate are respectively slidably mounted on the support guide rail, the rotation driving device is installed on the slide plate, and the rotation drive The output shaft provided on the device passes through the slide plate from downward. By installing the rotary drive device on the slide plate, and the two ends of the slide plate are slidably mounted on the supporting guide rails respectively, so that the rotary drive device can be moved easily.

According to an embodiment of the present invention, the hollow barrel body includes a dewaxing barrel for dewaxing pathological slides, a dehydration barrel for dehydrating pathological slides, and a storage dye for pathological slides. Dye barrels for staining, washing barrels for cleaning pathological slides, draining barrels for draining pathological slides, the dewaxing barrels, dehydration barrels, dye barrels, washing barrels and draining barrels Each is equipped with a plurality of draining buckets, and the draining buckets are respectively arranged at the rear ends of the dewaxing buckets, dehydrating buckets, dye buckets and cleaning buckets. By providing multiple dewaxing buckets, dehydration buckets, dye buckets, cleaning buckets and draining buckets, the dewaxing agents used to dewax pathological slides are stored in the dewaxing buckets, which is beneficial to the pathological slides. Dewaxing; dehydrating agents used to dehydrate pathological slides are stored in dehydration buckets, which is beneficial to dehydration of pathological slides; dyes used for staining pathological slides are stored in dye buckets, which is beneficial to Stain the pathological slides; respectively store cleaning solutions for cleaning the pathological slides in the cleaning barrel, which is beneficial to cleaning the pathological slides; in addition, the draining barrels are respectively arranged in the dewaxing barrel, The rear end of the barrel, dye barrel and cleaning barrel is conducive to draining the pathological slides after dewaxing, dehydrating, staining and cleaning the pathological slides in the draining barrel, and then entering the next process to prevent the previous staining The dyes or reagents in the process are brought into the next process, and the dyes or reagents in the next process are maintained to maintain the purity of each dye or reagent, which is conducive to improving the dyeing effect, and can reduce the replacement frequency of dyes or reagents and save reagents.

In addition, the present invention also provides a method for staining pathological slides, using the above-mentioned pathological slide staining device for staining, which includes the following steps:

Install the pathological slides on the slide mounting rack, extend the slide mounting rack with the pathological slides into the cavity of the cavity barrel through the lifting device, and turn on the rotating drive device to carry out dyeing;

moving the slide mounting frame containing pathological slides out of the cavity of the cavity barrel through the lifting device;

The pathological slide is subjected to the next staining process until the staining is completed.

The pathological glass slide is dyed by the method for staining the pathological glass slide of the present invention. During the dyeing process, the pathological glass slide can be in rapid contact with the dye, and the contact is even, the dyeing efficiency is high, and the dyeing uniformity is good.

Description of drawings

In order to illustrate the technical solutions in the present invention more clearly, the following will briefly introduce the accompanying drawings used in the description of the embodiments. Obviously, the accompanying drawings in the following description are only some embodiments of the application. Those of ordinary skill in the art can also obtain other drawings based on these drawings without any creative effort.

1 is a schematic diagram of the overall structure of a pathological glass slide staining device according to an embodiment of the present invention;

Fig. 2 is a schematic diagram of Fig. 1 after the hollow barrel directly below the variable-speed drive motor has descended;

Fig. 3 is the right side view after the straightening of Fig. 1;

4 is a schematic diagram of a variable speed drive motor extending into a cavity barrel according to an embodiment of the present invention;

5 is a schematic diagram of the variable speed drive motor moving out of the cavity barrel according to the embodiment of the present invention;

Fig. 6 is a structural schematic diagram of the variable speed drive motor in Fig. 5 being installed on a slide plate;

Fig. 7 is a structural schematic diagram of the connection between the slide mounting rack and the variable speed drive motor according to the embodiment of the present invention;

8 is a schematic structural view of a slide mounting rack according to an embodiment of the present invention;

Fig. 9 is a schematic structural diagram of a clamping block according to an embodiment of the present invention.

In the accompanying drawings, the list of parts represented by each label is as follows:

1. Support frame, 2. Variable speed drive motor, 3. Guide cylinder, 4. Cavity barrel, 5. Sliding plate, 6. Slide mounting frame, 7. Pathological slide, 8. Block, 9. Locking piece , 10, support base plate, 11, support column, 12, support guide rail, 20, output shaft, 21, mounting plate, 60, top plate, 61, bottom plate, 62, connecting shaft, 63, installation groove, 64, locking hole, 65, draw-in slot, 80, extraction groove, 121, guide chute, 601, bolt hole.

Detailed ways

In order to make the purpose, technical solution and advantages of the present application clearer, the implementation manners of the present application will be further described in detail below in conjunction with the accompanying drawings.

In order to understand the above-mentioned purpose, features and advantages of the present invention more clearly, the present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments. It should be noted that, in the case of no conflict, the embodiments of the present application and the features in the embodiments can be combined with each other.

In the following description, many specific details are set forth in order to fully understand the present invention. However, the present invention can also be implemented in other ways different from those described here. Therefore, the protection scope of the present invention is not limited by the specific details disclosed below. EXAMPLE LIMITATIONS.

An embodiment of the present disclosure provides a pathological glass slide staining device, as shown in FIGS. 6. The cavity barrel body 4 and the lifting device arranged under the glass slide mounting frame 6; the cavity barrel body 4 is connected with the lifting device; or the glass slide mounting frame 6 is connected with the rotating drive device, and the rotating drive device is installed through the lifting device In the support frame 1; the lifting device can drive the rotary drive device or the cavity barrel body 4 to move up and down, and the glass slide mounting frame 6 stretches into the cavity of the cavity barrel body 4 or moves out from the cavity of the cavity barrel body 4, And the slide mounting frame 6 can rotate under the drive of the rotary drive device.

In the embodiment of the present disclosure, dyes are put into the cavity barrel 4 in the pathological glass slide staining device, and the cavity barrel 4 or the slide mounting frame 6 can move up and down under the action of the lifting device, so as to realize the The slide mounting frame 6 extends into the cavity of the cavity barrel body 4, which is convenient to install the pathological glass slide 7 on the slide mounting frame 6 and then stretches it into the cavity of the cavity barrel body 4, and the rotary drive device is opened. The slide mounting frame 6 can be rotated under the drive of the rotary drive device, and the pathological slide 7 mounted on the slide mounting frame 6 is immersed in the dye and colored. After the coloring is completed, the rotary drive device stops, and the slide mounting frame 6 is removed. , you can enter the next dyeing process.

In the embodiment of the present disclosure, the lifting device is installed on the guide cylinder 3 through the guide cylinder 3 for installing the cavity barrel body 4, and the cavity barrel body 4 is adapted to be installed in the guide cylinder 3 and guided along the guide cylinder under the action of the lifting device. Tube 3 moves up and down. After the cavity barrel 4 in this embodiment moves downward, the slide mounting frame 6 moves out of the cavity barrel 4, and the slide mounting frame 6 can be moved horizontally to the next cavity barrel 4 for the next dyeing process .

In one embodiment of the present invention, as shown in Fig. 1 and Fig. 2, there are multiple cavity barrels 4, and the plurality of cavity barrels 4 are arranged at intervals along the length direction of the support frame 1, and the plurality of cavity barrels (4) The lifting device is connected respectively; the rotating drive device is slidably installed on the support frame 1, and can move horizontally along the length direction of the support frame 1 to the top of any cavity barrel 4.

In the embodiment of the present disclosure, a plurality of cavity barrels 4 are arranged at intervals along the length direction of the support frame 1, which is beneficial to adding dyes, dewaxing agents, dehydrating agents and cleaning solutions in different cavity barrels 4, and can also Directly use the cavity barrel 4 as the drain barrel; in addition, the rotary drive device is slidably installed on the support frame 1, and can move horizontally along the length direction of the support frame 1 to the top of any cavity barrel 4, which is convenient for installation The slide mounting frame 6 with pathological slides 7 is moved to the top of the cavity body 4 of different staining processes, and then the slide mounting frame 6 is extended into the cavity body 4 through the lifting device to carry out corresponding staining treatment, and then Then the lifting device moves the slide mounting frame 6 out of the cavity of the cavity barrel body 4, and enters the next process; the rotating drive device is moved in turn and the slide is stained, and through multiple processes, the slide is finished. Dyeing, the operation is more convenient. It should be noted that, in the embodiment of the present disclosure, only part of the cavity barrel 4 is shown in Figure 1 and Figure 2, but in fact, in this embodiment, each process needs to be provided with a cavity The barrel body 4 is used for staining the pathological glass slide 7, and the cavity barrel body 4 (not shown) is sequentially installed on the left side of Fig. 1 and Fig. 2 .

One embodiment of the present invention, as shown in Fig. 6 to Fig. 8, slide mounting frame 6 comprises top plate 60 and bottom plate 61, and top plate 60 is connected with rotary drive device, and bottom plate 61 is connected on the lower end of top plate 60 by connecting shaft 62, and top plate The lower side of the base plate 60 and the upper side of the bottom plate 61 are correspondingly provided with a plurality of mounting grooves 63 for mounting pathological slides 7 . In the embodiment of the present disclosure, the rotary driving device is a variable speed drive motor 2, the output shaft 20 on the variable speed drive motor 2 is set downward, and the end of the output shaft 20 is provided with a mounting plate 21, which is a cylindrical structure, and the mounting plate 21 is provided with a plurality of bolt holes; the top plate 60 is provided with bolt holes 601 corresponding to the plurality of bolt holes on the mounting plate 21, and the top plate 60 is fixed on the mounting plate 21 by bolts passing through the bolt holes, so as to realize the installation of the slides. The frame 6 is fixed on the output shaft 20 . The connecting shaft 62 in the embodiment of the present disclosure has a cylindrical structure and is connected to the central positions of the top plate 60 and the bottom plate 61 .

In addition, in the embodiment of the present disclosure, a plurality of installation grooves 63 for installing pathological slides 7 are provided on the slide mounting frame 6, which facilitates the installation of multiple pathological slides 7 and facilitates the installation of more pathological slides 7. It is beneficial to improve the staining efficiency of the pathological glass slide 7 .

In one embodiment of the present invention, as shown in FIGS. 6 to 8 , the top plate 60 and the bottom plate 61 are in a cylindrical structure, the connecting shaft 62 is connected to the central position of the top plate 60 and the bottom plate 61, and a plurality of mounting grooves 63 are arranged along the connecting shaft 62 Arranged in the circumferential direction, each installation groove 63 extends to the peripheral edge along the radial direction of the top plate 60 or the bottom plate 61, and several pathological glass slides 7 can be installed between the upper and lower opposite installation grooves 63 in the top plate 60 and the bottom plate 61 . In the embodiment of the present disclosure, by arranging a plurality of installation grooves 63 along the circumferential direction of the connecting shaft 62 , it is convenient to install the pathological glass slide 7 . In addition, in the embodiment of the present disclosure, a number of pathological glass slides 7 can be installed between every two oppositely opened installation grooves 63, which is conducive to installing more pathological glass slides 7 on the glass slide mounting rack 6, and is conducive to improving each The slide mounting frame 6 is the number of pathological slides 7 that have been stained in a single pass.

In the embodiment of the present disclosure, in order to facilitate the installation of the pathological glass slide 7, the installation groove 63 is arranged along the circumferential direction of the connecting shaft 62, and the outward end of the installation groove 63 is open, and every two opposite installation grooves 63 are opened. The vertical spacing is equal to the length of the pathological glass slide 7, or the vertical spacing between every two opposite installation grooves 63 is slightly greater than the length of the pathological glass slide 7, so that it is convenient to install along the opening from the outward end of the installation groove 63. The direction of the slot 63 installs the pathological glass slide 7 in the installation slot 63 .

In one embodiment of the present invention, as shown in Figure 7, the glass slide mounting frame 6 also includes a block 8, and the lower side of the top plate 60 and the edge of the upper side of the bottom plate 61 are all provided with a locking groove 65, and the locking groove 65 is compatible with the installation. The slots 63 are staggered and communicated, and the block 8 is adapted to be locked in the slots 65 and located outside the pathological glass slide 7 installed in the installation slots 63 . In the embodiment of the present disclosure, slots 65 are provided on the lower side of the top plate 60 and the upper side edge of the bottom plate 61, and the locking block 8 is adapted and snapped into the slots 65, so that the pathological glass installed in the installation slot 63 The slide 7 is defined to prevent the pathological slide 7 from detaching from the mounting groove 63 to the outside during the rotation process of the slide mounting frame 6 . In addition, in this embodiment, the pathological slide 7 can be fixed on the outside of the pathological slide 7 through the fixing rope pair, and the pathological slide 7 can also be fixed by other methods, which can prevent the pathological slide 7 from the mounting groove during the staining process. 63 can be separated from the inside to the outside. The clamping groove 65 in this embodiment is circular, and the clamping block 8 in this embodiment is provided with multiple pieces, and the clamping block 8 is an arc-shaped structure that is compatible with the clamping groove 65, as shown in Figure 9, and , as shown in Figure 6, each draw-in slot 65 can be installed with three blocks 8 that are abutted end to end, and the draw-in slot 65 and block 8 can also be provided with other shapes, which can block the pathological glass slide 7. .

In the embodiment of the present disclosure, in order to fix the block 8, a locking hole 64 is provided at intervals on the outer side of the top plate 60 and the bottom plate 61, the locking hole 64 communicates with the locking groove 65, and the locking member 9 is adapted to The fitting is screwed into the locking hole 64 and pressed against the outside of the clamping block 8, thereby fixing the clamping block 8. Further, in order to loosen the clamping block 8 and then take out the clamping block 8, the embodiment of the present disclosure also provides an extraction groove 80 on the outside of the clamping block 8, and an extraction tool is inserted into the extraction groove 80 to remove the clamping block 8 upwards.

In one embodiment of the present invention, as shown in FIG. 5 , the rotary drive device is a variable speed drive motor 2 , and the glass slide mounting frame 6 is installed on the output shaft 20 of the variable speed drive motor 2 . The embodiment of the disclosure adopts the variable speed drive motor 2 as the rotary drive device, which is beneficial to adjust the rotation speed of the slide mounting frame 6 by adjusting the speed of the variable speed drive motor 2, so that the pathological slide staining device can have multiple speeds, satisfying Different dyeing speed requirements can improve the uniformity of dyeing. In addition, when draining the pathological glass slide 7, by appropriately increasing the speed of the variable speed drive motor 2, it is beneficial to quickly and fully drain the pathological glass slide 7, which is conducive to improving the efficiency of draining and fully draining.

Further, in order to facilitate the power supply to the variable speed drive motor 2 in the embodiment of the present disclosure, a conductive slide bar may be provided, and the conductive slide bar and the conductive slide bar slide and move. Slides lengthwise and enables power delivery. Further, in the embodiment of the present disclosure, the variable speed drive motor 2 can be moved by personnel, and a horizontal moving device can also be installed to control the horizontal movement of the variable speed drive motor 2 manually, and a control system can also be provided to control its automatic movement. Move or stop for easy automation.

In one embodiment of the present invention, as shown in Fig. 1 and Fig. 2, the support frame 1 includes a pair of parallel and horizontally arranged support rails 12, and the rotation drive device is slidably installed on the support rails 12, and can be direction to move. In the embodiment of the present disclosure, a pair of parallel and horizontally arranged support guide rails 12 are provided on the support frame 1, which is beneficial for the rotary drive device to move horizontally on the support guide rails 12 to the top of any cavity barrel 4 and perform different processes. Dyeing treatment. In the embodiment of the present disclosure, the support frame 1 also includes a support base plate 10 and a support column 11, a pair of support base plates 10 are arranged in parallel, the support base plate 10 is horizontally fixed on a horizontal ground, and multiple support columns 11 are provided. They are vertically fixed on the upper side of the support base plate 10 at intervals, and the support guide rails 12 are fixedly connected to the top ends of a plurality of support columns 11 . In addition, the cavity barrel 4 in this embodiment is installed in the guide cylinder 3, and the guide cylinder 3 is placed on the upper side of the support base plate 10, and the upper side of the support base plate 10 can also be provided with threaded holes, and the guide cylinder The bottom of 3 is provided with threaded holes, and the guide cylinder 3 is fixed on the upper side of the support base plate 10 by bolts. The guide cylinder 3 is specifically installed at the position between the two support columns 11, and the cavity barrel 4 plays the role of the lifting device. Move up and down vertically along the guide cylinder 3.

In one embodiment of the present invention, as shown in Fig. 1 and Fig. 2, the pathological glass slide staining device further includes a slide plate 5, the two ends of the slide plate 5 are slidably mounted on the support rails 12 respectively, and the rotary drive device is installed on the slide plate 5, and The output shaft 20 provided on the rotary driving device passes through the slide plate 5 from downward. In the embodiment of the present disclosure, the rotation driving device is installed on the slide plate 5 , and the two ends of the slide plate 5 are slidingly installed on the supporting guide rails 12 respectively, so as to facilitate the movement of the rotation drive device. The slide plate 5 in this embodiment has a cuboid structure. In addition, in order to improve the reliability of the slide plate 5 moving on the support guide rail 12, the present embodiment also has a guide chute 121 on the support guide rail 12, and the guide chute 121 is opened horizontally. On the inner side of the supporting guide rail 12 , the two ends of the sliding plate 5 are adapted to be inserted into the guiding chute 121 , and the supporting guide rail 12 and the sliding plate 5 can also be arranged in other shapes.

In one embodiment of the present invention, the hollow barrel body 4 includes a dewaxing barrel for dewaxing the pathological glass slide 7, a dehydration barrel for dehydrating the pathological glass slide 7, and a dehydration barrel for storing dyes to dewax the pathological glass slide 7. 7 Dye bucket for staining, wash bucket for cleaning pathological slides 7, drain bucket for draining pathology slides 7, dewaxing bucket, dehydration bucket, dye bucket, wash bucket and drain There are multiple barrels, and the draining barrels are respectively arranged at the rear ends of the dewaxing barrel, the dehydrating barrel, the dye barrel and the cleaning barrel.

The embodiment of the present disclosure is provided with a plurality of dewaxing barrels, dehydration barrels, dye barrels, cleaning barrels and draining barrels, respectively storing dewaxing agents for dewaxing pathological glass slides 7 in the dewaxing barrels, which is beneficial to Dewaxing the pathological glass slide 7; storing dehydrating agents for dehydrating the pathological glass slide 7 in the dehydration bucket, which is beneficial to dehydrating the pathological glass slide 7; 7 dyeing dyes are conducive to staining the pathological slides 7; respectively storing cleaning liquid for cleaning the pathological slides 7 in the cleaning bucket is beneficial to cleaning the pathological slides 7; in addition, the draining bucket They are respectively arranged at the rear ends of the dewaxing bucket, dehydration bucket, dye bucket and cleaning bucket, which is beneficial to draining the pathological slide 7 after dewaxing, dehydrating, staining and cleaning the pathological slide 7 in the draining bucket. Then enter the next process to prevent the dyes or reagents from the previous dyeing process from being brought into the next process, and for the dyes or reagents in the next process, so as to maintain the purity of each dye or reagent, which is conducive to improving the dyeing effect and reducing the amount of dye. Or the replacement frequency of reagents to save reagents. Further, the cleaning barrel in this embodiment is also provided with an input pipe for inputting the cleaning liquid and an output pipe for outputting the cleaning liquid.

In the embodiment of the present disclosure, as shown in Figure 1 and Figure 2, the first hollow barrel 4 from right to left in this embodiment is a dewaxing barrel, and the second hollow barrel 4 is a draining barrel , the third hollow barrel 4 is a dewaxing barrel, put xylene I in the first hollow barrel 4, and put xylene II in the third hollow barrel 4. Put the slide mounting frame 6 with the pathological slide 7 into the first cavity barrel 4 to dehydrate the pathological slide 7 once, and move the slide mounting frame 6 out of the first cavity barrel after the first dehydration is completed 4. Move the slide mounting rack 6 to the top of the second cavity barrel 4, put the slide mounting rack 6 into the first cavity barrel 4, and drain the pathological slide 7 once. After completion, move the slide mounting frame 6 out of the second cavity barrel body 4, then move the slide mounting frame 6 to the top of the third cavity barrel body 4, and put the slide mounting frame 6 into the third cavity barrel body 4 again. The cavity barrel 4 dehydrates the pathological glass slide 7 for the second time, and then drains after the second dehydration is completed. In this way, the staining process of the pathological glass slide 7 is sequentially performed through multiple processes until the staining is completed. It should be noted that the dewaxing agent, dehydrating agent, dye, cleaning agent, etc. added in the hollow barrel 4 can be selected according to the dyeing process of the pathological slide 7 in the technical field, and will not be repeated here.

In addition, this embodiment also provides a method for staining pathological slides, using the above-mentioned pathological slide staining device for staining, which includes the following steps: installing the pathological slide 7 on the slide mounting frame 6, and moving the slide 7 through the lifting device. The slide mounting frame 6 equipped with the pathological glass slide 7 is extended into the cavity of the cavity barrel 4, and the rotating drive device is turned on for staining; the slide mounting frame 6 equipped with the pathological glass slide 7 is moved out by the lifting device The cavity of the cavity body 4; the pathological glass slide 7 is subjected to the next staining process until the staining is completed. The pathological slides are stained by the staining method of the pathological slides in the embodiment of the present disclosure. During the staining process, the pathological slides can be in rapid contact with the dye, and the contact is uniform, the staining efficiency is high, and the staining uniformity is good.

Specifically, by putting dye into the cavity body 4 in the pathological glass slide staining device of the present invention, the cavity body 4 or the slide mounting frame 6 can move up and down under the action of the lifting device, thereby realizing glass staining. The slide mounting frame 6 extends into the cavity of the cavity barrel body 4, which is convenient to install the pathological glass slide 7 on the slide mounting frame 6 and then stretches it into the cavity of the cavity barrel body 4, and the rotary drive device is opened. The glass slide mounting frame 6 can be rotated under the drive of the rotary drive device, which is conducive to the rapid contact between the pathological slide 7 and the dye during the staining process, and the contact is uniform, the staining efficiency is high, and the dyeing uniformity is good; the pathological slide 7 is dyed, The slide mounting frame 6 is removed from the cavity of the cavity barrel body 4, and then the next process can be entered. In addition, when the pathological glass slide staining device is provided with multiple cavity barrels 4, the rotary drive device is slidably installed on the support frame 1, and can move horizontally along the length direction of the support frame 1 to the top of any cavity barrel 4 In the case of this method, multiple rotary driving devices can be installed on the support frame 1, and the multiple rotary driving devices sequentially move to the station where any one of the cavity barrels 4 is located and complete the relevant process. The staining of the pathological glass slide 7 Efficiency is improved even more.

In addition, in addition to the technical solutions disclosed in the embodiments of the present disclosure, for the pathological glass slide 7, dyes, cleaning solutions, and staining procedures in the present invention, reference can be made to conventional technical solutions in the technical field, and these conventional technical solutions are not part of the present invention. focus, the present invention will not be described in detail here.

In the present invention, the term "plurality" refers to two or more, unless otherwise clearly defined. The terms "installation", "connection", "connection", "fixed" and other terms should be interpreted in a broad sense, for example, "connection" can be fixed connection, detachable connection, or integral connection; "connection" can be directly or indirectly through an intermediary. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention according to specific situations.

In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "front", "rear" etc. is based on the orientation or positional relationship shown in the drawings, and is only for convenience The present application and simplified description are described without indicating or implying that the referred device or unit must have a specific orientation, be constructed and operate in a specific orientation, and therefore, should not be construed as limiting the present application.

In the description of this specification, descriptions of the terms "one embodiment", "some embodiments", "specific embodiments" and the like mean that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in this application In at least one embodiment or example of . In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

The above are only preferred embodiments of the present application, and are not intended to limit the present application. For those skilled in the art, there may be various modifications and changes in the present application. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of this application shall be included within the protection scope of this application.

Claims (10)

1. A pathological slide staining device, characterized in that it comprises a support frame (1), a rotary drive device arranged on the support frame (1), a glass slide for installing the pathological slide (7) Mounting rack (6), cavity barrel body (4) and lifting device arranged below the slide mounting rack (6); The cavity barrel (4) is connected with the lifting device; Or the slide mounting frame (6) is connected to the rotary drive device, and the rotary drive device is installed on the support frame (1) through a lifting device; The lifting device can drive the rotary drive device or the cavity barrel (4) to move up and down, and the slide mounting frame (6) extends into the cavity of the cavity barrel (4) or from the cavity barrel (4). The cavity of the cavity barrel (4) is moved out, and the slide mounting frame (6) can be rotated under the drive of the rotary drive device. 2. A kind of pathological glass slide staining device according to claim 1, characterized in that, the cavity barrel (4) is provided with a plurality, and the plurality of cavity barrels (4) are arranged along the support The length direction of the frame (1) is arranged at intervals, and a plurality of the cavity barrels (4) are respectively connected with the lifting device; the rotation driving device is slidably installed on the support frame (1), and can be The length direction of the support frame (1) moves horizontally to the top of any one of the cavity barrels (4). 3. A kind of pathological slide staining device according to claim 1, is characterized in that, described slide mount (6) comprises top plate (60) and base plate (61), and described top plate (60) and described The rotary drive device is connected, and the base plate (61) is connected to the lower end of the top plate (60) through a connecting shaft (62), and the lower side of the top plate (60) and the upper side of the bottom plate (61) are correspondingly provided with A plurality of installation grooves (63) for installing the pathological glass slides (7). 4. A kind of pathological glass slide staining device according to claim 3, is characterized in that, described top board (60) and bottom board (61) all are cylindrical structure, and described connecting shaft (62) is connected on described top board (60) and the central position of the bottom plate (61), a plurality of said installation grooves (63) are arranged circumferentially along said connecting shaft (62), and each said installation groove (63) is respectively along said top plate (60) Or the radial direction of the bottom plate (61) extends to the peripheral edge, and several pathological glasses can be installed between the upper and lower relative installation grooves (63) in the top plate (60) and the bottom plate (61). slices (7). 5. A kind of pathological glass slide staining device according to claim 3, is characterized in that, also comprises block (8), and the lower side of described top plate (60) and the upper side edge of bottom plate (61) are all provided with A card slot (65), the card slot (65) intersects and communicates with the installation slot (63), the card block (8) is adapted to be clamped in the card slot (65) and is installed on the The outside of the pathological glass slide (7) in the above-mentioned installation groove (63). 6. A kind of pathological glass slide staining device according to any one of claims 1 to 5, characterized in that, the rotary drive device is a variable speed drive motor (2), and the slide mounting frame (6) is installed on on the output shaft (20) of the variable speed drive motor (2). 7. A kind of pathological slide staining device according to claim 2, characterized in that, the support frame (1) comprises a pair of parallel and horizontally arranged support guide rails (12), and the rotary drive device is slidably installed on The supporting rail (12) is mounted on and can move along the length direction of the supporting rail (12). 8. A kind of pathological glass slide staining device according to claim 7, is characterized in that, also comprises slide plate (5), and the two ends of described slide plate (5) are slidably installed on the described support guide rail (12) respectively, The rotary driving device is installed on the slide plate (5), and the output shaft (20) provided on the rotary driving device passes through the slide plate (5) from downward. 9. A pathological glass slide staining device according to any one of claims 1 to 5, 7 to 8, characterized in that, the cavity barrel (4) includes a pathological glass slide (7) Dewaxing bucket for dewaxing, dehydration bucket for dehydrating pathology slides (7), dye bucket for storing dyes for staining pathology slides (7), for staining pathology slides (7) A cleaning bucket for cleaning, a draining bucket for draining the pathological slides (7), the dewaxing bucket, the dehydration bucket, the dye bucket, the cleaning bucket and the draining bucket are provided with a plurality, and the draining bucket The buckets are respectively arranged at the rear ends of the dewaxing bucket, the dehydration bucket, the dye bucket and the cleaning bucket. 10. A method for staining pathological slides, characterized in that, using the pathological slide staining device according to any one of claims 1 to 9 for staining, it comprises the following steps: Install the pathological slide (7) on the slide mounting frame (6), and extend the slide mounting frame (6) with the pathological slide (7) into the cavity through the lifting device In the cavity of barrel body (4), open described rotary driving device and carry out dyeing; The slide mounting frame (6) equipped with pathological slides (7) is moved out of the cavity of the cavity barrel (4) by the lifting device; The pathological glass slide (7) is subjected to the next staining process until the staining is completed.