CN110338878A - A kind of thrombus acquisition equipment - Google Patents

Abstract

An embodiment of the present invention provides a thrombus capture device, which includes a recovery catheter, a delivery catheter, a traction guide wire, a blood vessel occlusion mechanism, a thrombus capture mechanism, a debris interception mechanism and a developing ring. When the device is working, through the simultaneous cooperation of the blood vessel blocking mechanism, the thrombus capturing mechanism and the debris intercepting mechanism, and with the auxiliary positioning of the developing ring, the thrombus and thrombus fragments can be captured and removed conveniently and effectively.

Description

A thrombus capture device

technical field

The invention belongs to the technical field of vascular disease treatment devices, and in particular relates to a thrombus capture device.

Background technique

In today's society, people's pace of life is accelerating, and bad living habits are common, leading to an increasing number of people suffering from vascular diseases. Thrombus is a blood clot formed by abnormal aggregation of red blood cells, platelets and fibrin in blood vessels in different proportions under the pathological conditions of the secondary endogenous or extrinsic coagulation system. Thrombosis may form in both arteries and veins, not limited to myocardial infarction, deep vein thrombosis, or cerebrovascular thrombosis. Thrombus can also spread throughout the body, tissues and organs, and occur in blood vessels anywhere in the body.

After thrombus forms in blood vessels, it will cause vascular occlusion and blockage of blood flow, causing ischemia, hypoxia and even necrosis of related vascular innervated tissues, resulting in symptoms of corresponding tissue and organ dysfunction. In the early stage, thrombolytic drugs were often used for treatment, but the therapeutic effect was not obvious, the recanalization rate was low, and the recanalization time was long. Moreover, drug thrombolytic therapy was only suitable for small thrombus, and had little effect on large-volume thrombus occlusion. Ideal, and only about 3 to 5% of patients are suitable for drug thrombolysis.

Mechanical thrombectomy provides patients with a new and highly effective method of recanalization therapy, which is to deliver the thrombus retriever to the lesion site, and then take the thrombus out of the body through the sheath. Mechanical thrombectomy is a research hotspot in the field of thrombus therapy due to its short operation time and few related complications. However, most of the mechanical thrombectomy devices currently used clinically have a single-layer stent structure. Not only is the ability to capture thrombus weak, but the efficiency of thrombus removal is low, and it needs to be pushed and pulled repeatedly during operation, resulting in the thrombus fragments in the blood vessel easily falling off and flowing. Distal vessels increase the risk of vascular reembolization in patients.

Contents of the invention

In order to solve the problems existing in the mechanical thrombectomy device in the prior art, the purpose of the embodiment of the present invention is to provide a thrombus capture device. When the device is working, the blood vessel occlusion mechanism, the thrombus capture mechanism and the debris interception mechanism cooperate at the same time. Function, and with the auxiliary positioning of the developing ring, the thrombus and thrombus fragments can be captured and removed conveniently and effectively.

In order to achieve the above purpose, the embodiment of the present invention adopts the following technical solutions:

A thrombus capture device, comprising:

recovery catheter;

a delivery catheter, the delivery catheter is movably sleeved in the recovery catheter;

a traction guide wire, the traction guide wire is arranged on the central axis in the delivery catheter, and moves along the direction of the central axis relative to the delivery catheter, and the traction guide wire has two ends: a pulling end and a pushing end;

A thrombus capture mechanism, the thrombus capture mechanism is fixed on the traction guide wire;

A blood vessel blocking mechanism, the blood vessel blocking mechanism is fixedly arranged on the pulling guide wire, between the pulling end and the thrombus capturing mechanism;

a debris intercepting mechanism, the debris intercepting mechanism is fixedly arranged on the pulling guide wire, between the pushing end and the thrombus capturing mechanism; and

A developing ring, the developing ring is fixedly wrapped around the pulling guide wire.

In the above thrombus capture device, the recovery catheter, the delivery catheter, the traction guide wire, the vessel occlusion mechanism, the thrombus capture mechanism, the debris interception mechanism and the imaging ring are all arranged coaxially. When not working, the above-mentioned mechanisms are all shrunk in the recovery conduit. When working, send the thrombus capture device according to the embodiment of the present invention near the thrombus in the blood vessel, fix the recovery catheter through the control system, then push the delivery catheter through the thrombus, fix the traction guide wire through the control system, and withdraw the delivery catheter To the exit of the recovery catheter, the blood vessel occlusion mechanism, the thrombus capture mechanism and the debris interception mechanism arranged on the traction guide wire are released into the blood vessel.

The vascular occlusion mechanism is an umbrella structure, which is trumpet-shaped when it is released. When the vascular occlusion mechanism is released into the blood vessel, it can contact the vessel wall and temporarily block the vessel to slow down the blood flow there. Prevent the blood flow in the blood vessel from impacting the thrombus, so as to facilitate the thrombus capture mechanism to capture the thrombus.

The thrombus capture mechanism is a net structure, which is olive-shaped when released. The recovery catheter and delivery catheter are fixed by the control system, and the traction guidewire is slowly withdrawn. During the withdrawal process, the thrombus capture mechanism captures the thrombus in the blood vessel.

The debris interception mechanism is a basket structure, which is in the shape of a net bag when it is released. When the debris interception mechanism is released into the blood vessel, it can intercept the thrombus fragments that may be generated when the thrombus is captured, filter and screen the blood, and can remove the thrombus fragments in the blood. Clear it all and prevent its flow to the distal vessels.

With the retraction of the traction guide wire, the vascular occlusion mechanism, the captured thrombus, the thrombus capture mechanism, and the debris interception mechanism are sequentially withdrawn into the recovery catheter, and then the thrombus capture device is smoothly withdrawn from the blood vessel, that is, the thrombus capture mechanism is completed. capture work.

The functions of the developing ring mainly include the following two points. (1) The use of the developing ring can precisely position the blood vessel blocking mechanism, the thrombus capturing mechanism and the debris intercepting mechanism in the thrombus capture device. The position of the vascular occlusion mechanism, the thrombus capture mechanism and the debris interception mechanism in the blood vessel can be clearly observed under the ray, and the operator can accurately and thoroughly complete the capture and removal of the thrombus and thrombus fragments; (2) adopt The development is wrapped around the traction guide wire, which can not only significantly increase the overall pushing and pulling ability of the traction guide wire, but also improve the connection strength between the vascular occlusion mechanism, the thrombus capture mechanism and the debris interception mechanism and the traction guide wire, which can be more Effectively enhance the safety of the thrombus capture device in use.

Preferably, the thrombus capture mechanism is a mesh structure.

The thrombus capture mechanism is a net structure, which is olive-shaped when released, and can fully support and expand the vessel wall, which is beneficial to capture thrombus.

Further preferably, the mesh structure is made of metal wire.

The mesh structure is made of metal wire, and the metal wire can be made of stainless steel, nickel-titanium alloy and cobalt-chromium alloy. When the network structure is contracted, it is in the shape of a network tube, and when the network structure is released, it is in the shape of an olive.

Preferably, the blood vessel occlusion mechanism is an umbrella structure, which is trumpet-shaped when it is released. The speed of the blood flow can prevent the blood flow in the blood vessel from impacting the thrombus, thereby facilitating the thrombus capture mechanism to capture the thrombus.

Further preferably, the umbrella structure is made of metal wire, and the metal wire can be made of materials such as stainless steel, nickel-titanium alloy, and cobalt-chromium alloy. When the umbrella body structure is contracted, it is in the shape of a net tube, and when the umbrella body structure is released, it is in the shape of a trumpet.

Preferably, the debris intercepting mechanism is a basket structure, which is in the shape of a net bag when released, and is used to intercept thrombus fragments that may be generated when the debris intercepting mechanism is released into the blood vessel, and to filter and screen the blood. Remove all thrombus fragments from the blood and prevent them from flowing to distant blood vessels.

Further preferably, the basket structure is made of metal wire, and the metal wire can be made of materials such as stainless steel, nickel-titanium alloy, and cobalt-chromium alloy. The basket structure is in the shape of a net tube in a contracted state, and in the shape of a net bag in a released state.

Preferably, the developing ring includes a first developing ring, a second developing ring and a third developing ring.

Further preferably, the material of the developing ring includes platinum-iridium alloy, platinum-tungsten alloy and platinum-iridium-tungsten alloy.

Further preferably, the first developing ring is arranged on the pulling guide wire at the proximal end of the blood vessel occlusion mechanism.

Further preferably, the second developing ring is arranged on the pulling guide wire at both ends of the thrombus capture mechanism.

Further preferably, the third developing ring is disposed on the pulling guide wire at the distal end of the debris intercepting mechanism.

When the blood vessel occlusion mechanism, the thrombus capture mechanism and the debris interception mechanism in the thrombus capture device of the embodiment of the present invention are in the released state at the same time, they can present different appearance structures so as to play their specific functions and thoroughly remove thrombus and thrombus Fragments, and easy to operate, meet the needs of clinical use.

Beneficial effects of the embodiments of the present invention

1. In the thrombus capture device provided by the embodiment of the present invention, under the cooperation of the blood vessel blocking mechanism, the thrombus capture mechanism and the debris interception mechanism, it has a strong ability to capture thrombus, and has high thrombus removal efficiency, and no need for Repeated pushing and pulling can remove the thrombus at one time, reducing the risk of re-embolization of the patient's blood vessels;

2. In a thrombus capture device provided by an embodiment of the present invention, by setting a vascular occlusion mechanism that can be contracted or released on the traction guide wire, the blood vessel can be temporarily occluded when the vascular occlusion mechanism is in a released state , which can prevent blood flow from impacting thrombus;

3. In a thrombus capture device provided by an embodiment of the present invention, by setting a thrombus capture mechanism that can be contracted or released on the traction guide wire, the vessel wall can be fully supported and expanded when the thrombus capture mechanism is in a released state, Capable of capturing thrombus in blood vessels;

4. In a thrombus capture device provided by an embodiment of the present invention, by setting a debris interception mechanism that can be contracted or released on the traction guide wire, the blood can be filtered and screened when the debris interception mechanism is in the released state, and the All of the thrombus debris is removed from the blood to prevent it from traveling to distant blood vessels.

Description of drawings

Fig. 1 is a schematic diagram of a contracted state of a thrombus capture device according to an embodiment of the present invention.

Fig. 2 is a schematic diagram of a released state of a thrombus capture device according to an embodiment of the present invention.

Fig. 3 is a schematic structural diagram of a developing ring of a thrombus capture device according to an embodiment of the present invention.

Fig. 4 is a working diagram of a thrombus capture device according to an embodiment of the present invention before passing through a thrombus.

Fig. 5 is a working schematic diagram of a thrombus capture device according to an embodiment of the present invention after passing through a thrombus.

Fig. 6 is a working schematic diagram of a thrombus capture mechanism in a thrombus capture device according to an embodiment of the present invention when it is released.

Fig. 7 is a working diagram of a thrombus capture device according to an embodiment of the present invention when capturing a thrombus.

Fig. 8 is a working diagram of a thrombus capture device according to an embodiment of the present invention when intercepting thrombus fragments.

FIG. 9 is a schematic diagram of a state in which the blood flow resumes normal operation after the thrombus and thrombus fragments are removed.

Detailed ways

An embodiment of the present invention provides a thrombus capture device, which includes a recovery catheter, a delivery catheter, a traction guide wire, a blood vessel occlusion mechanism, a thrombus capture mechanism, a debris interception mechanism and a developing ring. When the device is working, through the simultaneous cooperation of the blood vessel blocking mechanism, the thrombus capturing mechanism and the debris intercepting mechanism, and with the auxiliary positioning of the developing ring, the thrombus and thrombus fragments can be captured and removed conveniently and effectively.

In order to better understand the above technical solution, the above technical solution will be described in detail below in conjunction with specific implementation manners. It should be understood that the specific embodiments described here are only used to explain the present invention, but not to limit the present invention. In addition, it should be noted that, for the convenience of description, only the parts related to the present invention are shown in the drawings but not all of them. It should also be noted that the following description uses the terms "proximal end" and "distal end", wherein "proximal end" refers to the end close to the operator, and "distal end" refers to the end far away from the operator.

Example 1

A thrombus capture device, comprising:

Recovery catheter 1;

A delivery catheter 2, the delivery catheter 2 is movably sleeved in the recovery catheter 1;

A traction guide wire 3, the traction guide wire 3 is arranged on the central axis in the delivery catheter 2, and moves along the direction of the central axis relative to the delivery catheter 2, the traction guide wire 3 has two traction ends and a pusher end a terminal;

A thrombus capture mechanism 5, the thrombus capture mechanism 5 is fixedly arranged on the traction guide wire 3;

A blood vessel blocking mechanism 4, the blood vessel blocking mechanism 4 is fixedly arranged on the pulling guide wire 3, between the pulling end and the thrombus capturing mechanism 5;

A debris intercepting mechanism 6, said debris intercepting mechanism 6 is fixedly arranged on said traction guide wire 3, between said advancing end and said thrombus capturing mechanism 5; and

A developing ring 7 , the developing ring 7 is fixed around the pulling guide wire 3 .

In the above-mentioned thrombus capture device, the recovery catheter 1 , delivery catheter 2 , traction guide wire 3 , vessel occlusion mechanism 4 , thrombus capture mechanism 5 , debris interception mechanism 6 and development ring 7 are all arranged coaxially. In the non-working state, the above-mentioned mechanisms are all shrunk in the recovery catheter 1, as shown in FIG. 1 .

In the working state, as shown in Figure 2, the blood vessel blocking mechanism 4 is an umbrella structure, which is trumpet-shaped when released. Blocking to slow down the blood flow velocity in the place can prevent the blood flow in the blood vessel from impacting the thrombus, thereby facilitating the thrombus capture mechanism 5 to capture the thrombus.

The thrombus capture mechanism 5 has a mesh structure, and is olive-shaped when it is released. The recovery catheter 1 and the delivery catheter 2 are fixed by the control system, and the traction guide wire 3 is slowly withdrawn. During the withdrawal process, the thrombus capture mechanism 5 captures the Thrombus capture.

The debris interception mechanism 6 is a basket structure, and is in the shape of a net when it is released. When the debris interception mechanism 6 is released into the blood vessel, it can intercept the thrombus fragments that may be generated when the thrombus is captured, and filter and screen the blood. All thrombus debris is removed, preventing its flow to distal vessels.

The umbrella body structure of the blood vessel blocking mechanism 4 is made of metal wire, and the metal wire can be made of materials such as stainless steel, nickel-titanium alloy and cobalt-chromium alloy. When the umbrella body structure is contracted, it is in the shape of a net tube, and when the umbrella body structure is released, it is in the shape of a trumpet.

The mesh structure of the thrombus capture mechanism 5 is made of metal wire, and the metal wire can be made of materials such as stainless steel, nickel-titanium alloy, and cobalt-chromium alloy. When the network structure is contracted, it is in the shape of a network tube, and when the network structure is released, it is in the shape of an olive.

The basket structure of the debris intercepting mechanism 6 is made of wire material, and the wire can be selected from materials such as stainless steel, nickel-titanium alloy and cobalt-chromium alloy. The basket structure is in the shape of a net tube in a contracted state, and in the shape of a net bag in a released state.

As shown in FIG. 3 , the developing ring 7 is fixedly wrapped around the pulling guide wire 3 , and the developing ring 7 includes a first developing ring, a second developing ring and a third developing ring. The material of the developing ring 7 includes platinum-iridium alloy, platinum-tungsten alloy and platinum-iridium-tungsten alloy.

The first developing ring is arranged on the pulling guide wire 3 and at the proximal end of the blood vessel blocking mechanism 4 . The second developing ring is arranged on the pulling guide wire 3 and at both ends of the thrombus capturing mechanism 5 . The third developing ring is arranged on the pulling guide wire 3 and at the far end of the debris intercepting mechanism 6 .

The functions of the developing ring 7 mainly include the following two points. (1) The use of the developing ring 7 can precisely position the blood vessel blocking mechanism 4, the thrombus capturing mechanism 5 and the debris intercepting mechanism 6 in the thrombus capture device. , so that the operator can clearly observe the positions of the blood vessel occlusion mechanism 4, the thrombus capture mechanism 5 and the debris interception mechanism 6 in the blood vessel under X-ray, and enable the operator to accurately and thoroughly complete the detection of thrombus and thrombus fragments Capture and clearing work; (2) Adopting the developing ring 7 to be wound on the traction guide wire 3 can not only significantly increase the overall pushing and pulling capacity of the traction guide wire 3, but also can improve the blood vessel occlusion mechanism 4 and thrombus capture mechanism. 5 and the connection strength between the debris interception mechanism 6 and the traction guide wire 3 can more effectively enhance the safety of the thrombus capture device in use.

Example 2

When the thrombus capture device of the embodiment of the present invention works:

The recovery catheter 1 is sent into the vicinity of the thrombus 9 in the blood vessel 8 through the control system, as shown in FIG. 4 ;

The recovery catheter 1 is fixed by the control system, and then the delivery catheter 2 is pushed and passed through the thrombus 9, as shown in FIG. 5 ;

The traction guide wire 3 is fixed by the control system, and the delivery catheter 2 is retracted to the outlet of the recovery catheter 1, as shown in Figure 6, so that the blood vessel occlusion mechanism 4, the thrombus capture mechanism 5 and the fragments arranged on the traction guide wire 3 The intercepting mechanism 6 is released into the blood vessel 8, and the blood vessel blocking mechanism 4 is in the shape of a trumpet when it is released, contacts the blood vessel wall and temporarily blocks the blood vessel 8 to slow down the speed of blood flow there, and prevent the blood flow in the blood vessel 8 When the thrombus 9 is impacted, the thrombus capture mechanism 5 is in the shape of an olive when it is released, fully supports and expands the vessel wall, and captures the thrombus 9 in the blood vessel 8, and the debris interception mechanism 6 is in the shape of a net bag when it is released, intercepting and capturing the thrombus At 9 o'clock, the thrombus fragments 10 that may be generated are filtered and screened for the thrombus fragments 10 in the blood to prevent them from flowing to the distal blood vessel 8;

The recovery catheter 1 and the delivery catheter 2 are fixed by the control system, and the traction guide wire 3 is slowly withdrawn, as shown in FIG. Then, the recovery catheter 1, the delivery catheter 2 and the traction guide wire 3 are all withdrawn from the blood vessel 8 smoothly, and the capture of the thrombus 9 can be completed;

During the withdrawal process, as shown in Figure 8, the debris interception mechanism 6 can intercept the thrombus fragments 10 that may be generated when the thrombus 9 is captured, filter and screen the blood, and can remove all the thrombus fragments 10 in the blood to prevent them from flowing to distant places. terminal vessel 8;

As shown in FIG. 9 , after the thrombus 9 and thrombus fragments 10 are removed, the blood flow in the blood vessel 8 returns to a normal operating state.

Specific embodiments of the present invention have been described above. It should be understood that the present invention is not limited to the specific embodiments described above, and those skilled in the art may make various changes or modifications within the scope of the claims, which do not affect the essence of the present invention.

Claims (10)

1. a kind of thrombus acquisition equipment characterized by comprising

It recycles conduit (1)；

Delivery conduit (2), the delivery conduit (2) are movably set in the recycling conduit (1)；

It draws seal wire (3), traction seal wire (3) is set on the central axis in the delivery conduit (2), relative to described Delivery conduit (2) is moved along central axial direction, and the traction seal wire (3) has traction end and promotes two, end end；

Thrombus capture mechanism (5), the thrombus capture mechanism (5) are fixedly installed on the traction seal wire (3)；

Blood vessel plugging mechanism (4), the blood vessel plugging mechanism (4) is fixedly installed on the traction seal wire (3), the traction end Between the thrombus capture mechanism (5)；

Fragment interceptor structure (6), the fragment interceptor structure (6) is fixedly installed on the traction seal wire (3), the propulsion end Between the thrombus capture mechanism (5)；And

Developing ring (7), developing ring (7) fixation are surrounded on the traction seal wire (3).

2. thrombus acquisition equipment according to claim 1, which is characterized in that the blood vessel plugging mechanism (4) is umbrella body knot Structure.

3. thrombus acquisition equipment according to claim 1, which is characterized in that the thrombus capture mechanism (5) is dictyosome knot Structure.

4. thrombus acquisition equipment according to claim 3, which is characterized in that the dictyosome structure is wire material.

5. thrombus acquisition equipment according to claim 1, which is characterized in that the fragment interceptor structure (6) is basket body knot Structure.

6. thrombus acquisition equipment according to claim 1, which is characterized in that the developing ring (7) include the first developing ring, Second developing ring and third developing ring.

7. thrombus acquisition equipment according to claim 1, which is characterized in that the material of the developing ring (7) includes platinoiridita Alloy, platinum-tungsten alloys and platinoiridita tungsten alloy.

8. thrombus acquisition equipment according to claim 6, which is characterized in that first developing ring is set to the traction On seal wire (3), the proximal end of blood vessel plugging mechanism (4).

9. thrombus acquisition equipment according to claim 6, which is characterized in that second developing ring is set to the traction On seal wire (3), the both ends of thrombus capture mechanism (5).

10. thrombus acquisition equipment according to claim 6, which is characterized in that the third developing ring is set to described lead In guide wire (3), the distal end of fragment interceptor structure (6).