CN110244037B - Chemiluminescent detection module - Google Patents
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- 238000001514 detection method Methods 0.000 title claims abstract description 35
- 230000007246 mechanism Effects 0.000 claims abstract description 63
- 239000007788 liquid Substances 0.000 claims abstract description 59
- 239000002699 waste material Substances 0.000 claims abstract description 45
- 238000012795 verification Methods 0.000 claims abstract description 28
- 230000003287 optical effect Effects 0.000 claims abstract description 13
- 239000000758 substrate Substances 0.000 claims description 23
- 230000001360 synchronised effect Effects 0.000 claims description 15
- 238000007599 discharging Methods 0.000 claims 2
- 238000005213 imbibition Methods 0.000 claims 2
- 230000000903 blocking effect Effects 0.000 abstract 1
- 238000002038 chemiluminescence detection Methods 0.000 description 19
- 101000623895 Bos taurus Mucin-15 Proteins 0.000 description 10
- 238000012546 transfer Methods 0.000 description 8
- 238000010586 diagram Methods 0.000 description 6
- 238000000338 in vitro Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- 101001121408 Homo sapiens L-amino-acid oxidase Proteins 0.000 description 1
- 101000827703 Homo sapiens Polyphosphoinositide phosphatase Proteins 0.000 description 1
- 102100026388 L-amino-acid oxidase Human genes 0.000 description 1
- 102100023591 Polyphosphoinositide phosphatase Human genes 0.000 description 1
- 101100012902 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) FIG2 gene Proteins 0.000 description 1
- 101100233916 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) KAR5 gene Proteins 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
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- 230000000694 effects Effects 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
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Abstract
Description
技术领域Technical Field
本发明涉及一种化学发光检测模组，属于体外诊断器械技术领域。The invention relates to a chemiluminescence detection module, belonging to the technical field of in vitro diagnostic instruments.
背景技术Background technique
化学发光免疫分析技术由于其较高的准确度，广泛应用于体外诊断领域。其原理是将待测样本放入反应杯中，将反应杯放入检测暗室中，加注底物，样本发光，通过光路将光子投射到光电倍增管上进行接收、检测从而实现化学发光分析。由于化学发光本身特点，发出的光是瞬光或辉光，所以传统技术方案难以保证检测暗室的避光性，经常受外界杂光的干扰是化学发光分析仪的关，并且检测模块无法与抓手模块快速配合，反应杯的更换速度慢，并且检测物发出的瞬光或辉光不能进行有效汇聚，影响检测结果，亟需一种化学发光检测技术方案。Chemiluminescent immunoassay technology is widely used in the field of in vitro diagnosis due to its high accuracy. The principle is to put the sample to be tested into a reaction cup, put the reaction cup into the detection darkroom, add the substrate, the sample emits light, and project the photons through the optical path to the photomultiplier tube for reception and detection to achieve chemiluminescent analysis. Due to the characteristics of chemiluminescence itself, the light emitted is a flash or glow, so it is difficult for traditional technical solutions to ensure the light-proofness of the detection darkroom. Frequent interference from external stray light is the problem of chemiluminescence analyzers, and the detection module cannot cooperate quickly with the gripper module. The replacement speed of the reaction cup is slow, and the flash or glow emitted by the test object cannot be effectively converged, affecting the test results. A chemiluminescent detection technology solution is urgently needed.
发明内容Summary of the invention
本发明针对现有技术存在的不足，提供一种化学发光检测模组，可以实现反应杯的快速更换，又可以使检测物发出的瞬光或辉光有效的汇聚到光电倍增管上，同时避免外界杂光的进入和干扰。In view of the deficiencies in the prior art, the present invention provides a chemiluminescence detection module, which can realize the rapid replacement of reaction cups and can effectively converge the instantaneous light or glow emitted by the detection object onto the photomultiplier tube, while avoiding the entry and interference of external stray light.
本发明解决上述技术问题的技术方案如下：一种化学发光检测模组，包括光路组件、校验组件、暗室机构和废液吸取机构；所述光路组件包括光电倍增管、导光棒和聚光杯，所述光电倍增管连接所述导光棒，所述聚光杯设置在所述导光棒的侧部；所述校验组件包括透镜、光阑、衰减片和光源，所述透镜连接在所述聚光杯的外侧，所述光阑连接在所述透镜的外侧，所述衰减片连接所述光阑的外侧，所述光源连接在所述衰减片的外侧，光源发出的光依次经过所述衰减片、光阑和透镜投射到所述光电倍增管；所述暗室机构设置在所述校验组件的外侧，暗室机构阻挡外界环境光线向所述校验组件投射；所述废液吸取机构连接所述暗室机构，废液吸取机构对所述聚光杯内的废液进行吸取。The technical solution of the present invention to solve the above technical problems is as follows: a chemiluminescence detection module, comprising an optical path component, a verification component, a darkroom mechanism and a waste liquid suction mechanism; the optical path component comprises a photomultiplier tube, a light guide rod and a focusing cup, the photomultiplier tube is connected to the light guide rod, and the focusing cup is arranged on the side of the light guide rod; the verification component comprises a lens, an aperture, an attenuation plate and a light source, the lens is connected to the outside of the focusing cup, the aperture is connected to the outside of the lens, the attenuation plate is connected to the outside of the aperture, the light source is connected to the outside of the attenuation plate, and the light emitted by the light source is projected onto the photomultiplier tube through the attenuation plate, the aperture and the lens in sequence; the darkroom mechanism is arranged on the outside of the verification component, and the darkroom mechanism blocks the external ambient light from being projected onto the verification component; the waste liquid suction mechanism is connected to the darkroom mechanism, and the waste liquid suction mechanism absorbs the waste liquid in the focusing cup.
作为化学发光检测模组的优选方案，所述暗室机构包括安装板和遮光板，所述遮光板通过第一迷宫结构连接在所述安装板的侧部，所述安装板的侧部设有第一导轨，安装板的顶部连接有上盖，所述遮光板连接所述第一导轨。As a preferred solution for the chemiluminescence detection module, the darkroom mechanism includes a mounting plate and a shading plate, the shading plate is connected to the side of the mounting plate through a first maze structure, a first guide rail is provided on the side of the mounting plate, an upper cover is connected to the top of the mounting plate, and the shading plate is connected to the first guide rail.
作为化学发光检测模组的优选方案，所述遮光板连接有牵拉弹簧，所述牵拉弹簧连接在所述安装板的侧部。As a preferred solution of the chemiluminescence detection module, the shading plate is connected to a pulling spring, and the pulling spring is connected to the side of the mounting plate.
作为化学发光检测模组的优选方案，所述安装板的侧部设有第二导轨，所述第二导轨、上盖通过第二迷宫结构连接有放置反应杯的杯托，所述杯托连接有驱动带，所述驱动带连接有固定于所述安装板侧部的第一电机。As a preferred solution for the chemiluminescence detection module, a second guide rail is provided on the side of the mounting plate, and the second guide rail and the upper cover are connected to a cup holder for placing a reaction cup through a second maze structure, and the cup holder is connected to a drive belt, and the drive belt is connected to a first motor fixed to the side of the mounting plate.
作为化学发光检测模组的优选方案，校验组件设置在所述杯托的内部，所述杯托端部连接有电路板，校验组件的光源连接在所述电路板上。As a preferred solution of the chemiluminescence detection module, the verification component is arranged inside the cup holder, the end of the cup holder is connected to a circuit board, and the light source of the verification component is connected to the circuit board.
作为化学发光检测模组的优选方案，所述暗室机构的顶部设有底物接头，所述底物接头连通反应杯，底物接头配置有底物管路，所述底物管路连接有旋转柱塞泵。As a preferred solution of the chemiluminescent detection module, a substrate connector is provided on the top of the darkroom mechanism, the substrate connector is connected to the reaction cup, the substrate connector is configured with a substrate pipeline, and the substrate pipeline is connected to a rotary plunger pump.
作为化学发光检测模组的优选方案，所述废液吸取机构包括第二电机、第三导轨、同步带和吸废液组件，所述第二电机连接在所述暗室机构的下方，所述第三导轨连接在所述暗室机构的侧部，所述同步带通过带轮连接在所述暗室机构的侧部，所述带轮连接所述第二电机，所述吸废液组件连接所述同步带。As a preferred solution of the chemiluminescence detection module, the waste liquid suction mechanism includes a second motor, a third guide rail, a synchronous belt and a waste liquid suction component, the second motor is connected to the bottom of the dark chamber mechanism, the third guide rail is connected to the side of the dark chamber mechanism, the synchronous belt is connected to the side of the dark chamber mechanism through a pulley, the pulley is connected to the second motor, and the waste liquid suction component is connected to the synchronous belt.
作为化学发光检测模组的优选方案，所述同步带连接有转接块，所述转接块沿所述第二导轨进行滑动，所述吸废液组件连接在所述转接块的上方。As a preferred solution of the chemiluminescence detection module, the synchronous belt is connected to a transfer block, the transfer block slides along the second guide rail, and the waste liquid suction component is connected above the transfer block.
作为化学发光检测模组的优选方案，所述吸废液组件包括提升杆、横臂、针座和吸液针，所述提升杆连接在所述转接块的上方，所述横臂连接在所述提升杆的顶部，横臂延伸至暗室机构的上方，所述针座连接在所述横臂的末端，所述吸液针连接在所述针座的下方。As a preferred solution of the chemiluminescence detection module, the waste liquid suction component includes a lifting rod, a cross arm, a needle seat and a liquid suction needle, the lifting rod is connected above the adapter block, the cross arm is connected to the top of the lifting rod, the cross arm extends to the top of the darkroom mechanism, the needle seat is connected to the end of the cross arm, and the liquid suction needle is connected below the needle seat.
作为化学发光检测模组的优选方案，所述吸液针连接有排液管，所述排液管连接有吸液泵。As a preferred solution of the chemiluminescence detection module, the aspiration needle is connected to a drainage tube, and the drainage tube is connected to a suction pump.
本发明的有益效果是：设有光路组件、校验组件、暗室机构和废液吸取机构；光路组件设有光电倍增管、导光棒和聚光杯，光电倍增管连接导光棒，聚光杯设置在导光棒的侧部；校验组件设有透镜、光阑、衰减片和光源，透镜连接在聚光杯的外侧，光阑连接在透镜的外侧，衰减片连接光阑的外侧，光源连接在衰减片的外侧，光源发出的光依次经过衰减片、光阑和透镜投射到光电倍增管；暗室机构设置在校验组件的外侧，暗室机构阻挡外界环境光线向校验组件投射；废液吸取机构连接暗室机构，废液吸取机构对聚光杯内的废液进行吸取。本技术方案可以实现反应杯的快速更换，又可以使检测物发出的瞬光或辉光有效的汇聚到光电倍增管上，同时避免外界杂光的进入和干扰，检测结果准确度高。The beneficial effects of the present invention are as follows: an optical path component, a verification component, a darkroom mechanism and a waste liquid suction mechanism are provided; the optical path component is provided with a photomultiplier tube, a light guide rod and a focusing cup, the photomultiplier tube is connected to the light guide rod, and the focusing cup is arranged on the side of the light guide rod; the verification component is provided with a lens, an aperture, an attenuation plate and a light source, the lens is connected to the outside of the focusing cup, the aperture is connected to the outside of the lens, the attenuation plate is connected to the outside of the aperture, the light source is connected to the outside of the attenuation plate, and the light emitted by the light source is sequentially projected to the photomultiplier tube through the attenuation plate, the aperture and the lens; the darkroom mechanism is arranged on the outside of the verification component, and the darkroom mechanism blocks the external ambient light from being projected to the verification component; the waste liquid suction mechanism is connected to the darkroom mechanism, and the waste liquid suction mechanism absorbs the waste liquid in the focusing cup. This technical solution can realize the rapid replacement of the reaction cup, and can effectively converge the instantaneous light or glow emitted by the detection object onto the photomultiplier tube, while avoiding the entry and interference of external stray light, and the detection result has high accuracy.
附图说明BRIEF DESCRIPTION OF THE DRAWINGS
为了更清楚地说明本发明的实施方式或现有技术中的技术方案，下面将对实施方式或现有技术描述中所需要使用的附图作简单地介绍。显而易见地，下面描述中的附图仅仅是示例性的，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据提供的附图引伸获得其它的实施附图。In order to more clearly illustrate the implementation of the present invention or the technical solution in the prior art, the following briefly introduces the drawings required for the implementation or the prior art description. Obviously, the drawings in the following description are only exemplary, and for ordinary technicians in this field, other implementation drawings can be derived from the provided drawings without creative work.
本说明书所绘示的结构、比例、大小等，均仅用以配合说明书所揭示的内容，以供熟悉此技术的人士了解与阅读，并非用以限定本发明可实施的限定条件，故不具技术上的实质意义，任何结构的修饰、比例关系的改变或大小的调整，在不影响本发明所能产生的功效及所能达成的目的下，均应仍落在本发明所揭示的技术内容得能涵盖的范围内。The structures, proportions, sizes, etc. illustrated in this specification are only used to match the contents disclosed in the specification so as to facilitate understanding and reading by persons familiar with the technology. They are not used to limit the conditions under which the present invention can be implemented, and therefore have no substantial technical significance. Any structural modification, change in proportion or adjustment of size shall still fall within the scope of the technical contents disclosed in the present invention without affecting the effects and purposes that can be achieved by the present invention.
图1为本发明实施例中提供的化学发光检测模组外部结构示意图；FIG1 is a schematic diagram of the external structure of a chemiluminescence detection module provided in an embodiment of the present invention;
图2为本发明实施例中提供的化学发光检测模组内部结构示意图；FIG2 is a schematic diagram of the internal structure of a chemiluminescence detection module provided in an embodiment of the present invention;
图3为本发明实施例中提供的化学发光检测模组光路组件和校验组件结构示意图；FIG3 is a schematic diagram of the structure of the optical path component and the verification component of the chemiluminescence detection module provided in an embodiment of the present invention;
图4为本发明实施例中提供的化学发光检测模组暗室机构内部示意图；FIG4 is a schematic diagram of the interior of a darkroom mechanism of a chemiluminescence detection module provided in an embodiment of the present invention;
图5为本发明实施例中提供的化学发光检测模组遮光板与安装板配合结构示意图；FIG5 is a schematic diagram of the matching structure of the chemiluminescence detection module light shielding plate and the mounting plate provided in an embodiment of the present invention;
图6为本发明实施例中提供的化学发光检测模组杯托和遮光板配合结构示意图。FIG. 6 is a schematic diagram of the coordination structure of the cup holder and the light shielding plate of the chemiluminescence detection module provided in an embodiment of the present invention.
图中，I、光路组件；II、校验组件；III、暗室机构；IV、废液吸取机构；In the figure, I, optical path component; II, calibration component; III, darkroom mechanism; IV, waste liquid suction mechanism;
1、光电倍增管；2、导光棒；3、聚光杯；4、透镜；5、光阑；6、衰减片；7、光源；8、安装板；9、遮光板；10、第一迷宫结构；11、第一导轨；12、牵拉弹簧；13、第二导轨；14、第二迷宫结构；15、杯托；16、驱动带；17、第一电机；18、电路板；19、底物接头；20、第二电机；21、第三导轨；22、同步带；23、转接块；24、提升杆；25、横臂；26、针座；27、吸液针；28、反应杯；29、上盖。1. Photomultiplier tube; 2. Light guide rod; 3. Focusing cup; 4. Lens; 5. Aperture; 6. Attenuation plate; 7. Light source; 8. Mounting plate; 9. Shading plate; 10. First maze structure; 11. First guide rail; 12. Pull spring; 13. Second guide rail; 14. Second maze structure; 15. Cup holder; 16. Drive belt; 17. First motor; 18. Circuit board; 19. Substrate connector; 20. Second motor; 21. Third guide rail; 22. Synchronous belt; 23. Adapter block; 24. Lifting rod; 25. Cross arm; 26. Needle holder; 27. Pipette needle; 28. Reaction cup; 29. Upper cover.
具体实施方式Detailed ways
为使本发明的上述目的、特征和优点能够更加明显易懂，下面结合附图对本发明的具体实施方式做详细的说明。在下面的描述中阐述了很多具体细节以便于充分理解本发明。但是本发明能够以很多不同于在此描述的其它方式来实施，本领域技术人员可以在不违背本发明内涵的情况下做类似改进，因此本发明不受下面公开的具体实施例的限制。In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.
除非另有定义，本文所使用的所有的技术和科学术语与属于本发明的技术领域的技术人员通常理解的含义相同。本文中在本发明的说明书中所使用的术语只是为了描述具体的实施方式的目的，不是旨在于限制本发明。本文所使用的术语“和/或”包括一个或多个相关的所列项目的任意的和所有的组合。Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art of the present invention. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and/or" used herein includes any and all combinations of one or more related listed items.
参见图1和图2，提供一种化学发光检测模组，包括光路组件I、校验组件II、暗室机构III和废液吸取机构IV；所述光路组件I包括光电倍增管1、导光棒2和聚光杯3，所述光电倍增管1连接所述导光棒2，所述聚光杯3设置在所述导光棒2的侧部；所述校验组件II包括透镜4、光阑5、衰减片6和光源7，所述透镜4连接在所述聚光杯3的外侧，所述光阑5连接在所述透镜4的外侧，所述衰减片6连接所述光阑5的外侧，所述光源7连接在所述衰减片6的外侧，光源7发出的光依次经过所述衰减片6、光阑5和透镜4投射到所述光电倍增管1；所述暗室机构III设置在所述校验组件II的外侧，暗室机构III阻挡外界环境光线向所述校验组件II投射；所述废液吸取机构IV连接所述暗室机构III，废液吸取机构IV对所述聚光杯3内的废液进行吸取。Referring to Figures 1 and 2, a chemiluminescence detection module is provided, including an optical path component I, a verification component II, a darkroom mechanism III and a waste liquid suction mechanism IV; the optical path component I includes a photomultiplier tube 1, a light guide rod 2 and a focusing cup 3, the photomultiplier tube 1 is connected to the light guide rod 2, and the focusing cup 3 is arranged on the side of the light guide rod 2; the verification component II includes a lens 4, an aperture 5, an attenuation plate 6 and a light source 7, the lens 4 is connected to the outside of the focusing cup 3, the aperture 5 is connected to the outside of the lens 4, the attenuation plate 6 is connected to the outside of the aperture 5, the light source 7 is connected to the outside of the attenuation plate 6, and the light emitted by the light source 7 is sequentially projected onto the photomultiplier tube 1 through the attenuation plate 6, the aperture 5 and the lens 4; the darkroom mechanism III is arranged on the outside of the verification component II, and the darkroom mechanism III blocks the external ambient light from being projected onto the verification component II; the waste liquid suction mechanism IV is connected to the darkroom mechanism III, and the waste liquid suction mechanism IV absorbs the waste liquid in the focusing cup 3.
参见图5和图6，化学发光检测模组的一个实施例中，所述暗室机构III包括安装板8和遮光板9，所述遮光板9通过第一迷宫结构10连接在所述安装板8的侧部，所述安装板8的侧部设有第一导轨11，安装板8的顶部连接有上盖29，所述遮光板9连接所述第一导轨11。所述遮光板9连接有牵拉弹簧12，所述牵拉弹簧12连接在所述安装板8的侧部。所述安装板8的侧部设有第二导轨13，所述第二导轨13和上盖29通过第二迷宫结构14连接有放置反应杯28的杯托15，所述杯托15连接有驱动带16，所述驱动带16连接有固定于所述安装板8侧部的第一电机17。第一电机17通过驱动带16能够带动杯托15沿第二导轨13移动。第一迷宫结构10和第二迷宫结构14通过设有若干次的翻折实现对外界环境光的遮挡，遮光板9能够沿第一导轨11上滑动，在非检测状态下遮挡光电倍增管1，避免光电倍增管1受到外界杂光干扰。Referring to FIG. 5 and FIG. 6 , in one embodiment of the chemiluminescence detection module, the darkroom mechanism III includes a mounting plate 8 and a shading plate 9, the shading plate 9 is connected to the side of the mounting plate 8 through a first maze structure 10, a first guide rail 11 is provided on the side of the mounting plate 8, a top cover 29 is connected to the top of the mounting plate 8, and the shading plate 9 is connected to the first guide rail 11. The shading plate 9 is connected to a pulling spring 12, and the pulling spring 12 is connected to the side of the mounting plate 8. A second guide rail 13 is provided on the side of the mounting plate 8, and the second guide rail 13 and the top cover 29 are connected to a cup holder 15 for placing a reaction cup 28 through a second maze structure 14, and the cup holder 15 is connected to a driving belt 16, and the driving belt 16 is connected to a first motor 17 fixed to the side of the mounting plate 8. The first motor 17 can drive the cup holder 15 to move along the second guide rail 13 through the driving belt 16. The first maze structure 10 and the second maze structure 14 are provided with a plurality of folds to shield the external ambient light. The shading plate 9 can slide along the first guide rail 11 to shield the photomultiplier tube 1 in a non-detection state to prevent the photomultiplier tube 1 from being disturbed by external stray light.
参见图3和图4，化学发光检测模组的一个实施例中，校验组件II设置在所述杯托15的内部，所述杯托15端部连接有电路板18，校验组件II的光源7连接在所述电路板18上。所述暗室机构III的顶部设有底物接头19，所述底物接头19连通反应杯28，底物接头19配置有底物管路，所述底物管路连接有旋转柱塞泵(底物管路和旋转柱塞泵附设结构未示出)。底物接头19用于向反应杯28中添加反应底物，电路板18上的光源7发出光，聚光杯3汇聚底物发出的光，通过导光棒2投射到光电倍增管1上。Referring to FIG. 3 and FIG. 4 , in one embodiment of the chemiluminescent detection module, the verification component II is arranged inside the cup holder 15, the end of the cup holder 15 is connected to a circuit board 18, and the light source 7 of the verification component II is connected to the circuit board 18. A substrate connector 19 is arranged on the top of the darkroom mechanism III, the substrate connector 19 is connected to the reaction cup 28, the substrate connector 19 is provided with a substrate pipeline, and the substrate pipeline is connected to a rotary piston pump (the substrate pipeline and the rotary piston pump attached structure are not shown). The substrate connector 19 is used to add a reaction substrate to the reaction cup 28, the light source 7 on the circuit board 18 emits light, the focusing cup 3 gathers the light emitted by the substrate, and projects it onto the photomultiplier tube 1 through the light guide rod 2.
参见图2，化学发光检测模组的一个实施例中，所述废液吸取机构IV包括第二电机20、第三导轨21、同步带22和吸废液组件，所述第二电机20连接在所述暗室机构III的下方，所述第三导轨21连接在所述暗室机构III的侧部，所述同步带22通过带轮连接在所述暗室机构III的侧部，所述带轮连接所述第二电机20，所述吸废液组件连接所述同步带22。所述同步带22连接有转接块23，所述转接块23沿所述第三导轨21进行滑动，所述吸废液组件连接在所述转接块23的上方。第二电机20通过带轮驱动同步带22运转，同步带22运转时转接块23沿第三导轨21上下移动，进而实现与转接块23连接的吸废液组件上下移动。Referring to Fig. 2, in one embodiment of the chemiluminescent detection module, the waste liquid suction mechanism IV includes a second motor 20, a third guide rail 21, a synchronous belt 22 and a waste liquid suction component, wherein the second motor 20 is connected to the bottom of the darkroom mechanism III, the third guide rail 21 is connected to the side of the darkroom mechanism III, the synchronous belt 22 is connected to the side of the darkroom mechanism III through a pulley, the pulley is connected to the second motor 20, and the waste liquid suction component is connected to the synchronous belt 22. The synchronous belt 22 is connected to a transfer block 23, the transfer block 23 slides along the third guide rail 21, and the waste liquid suction component is connected above the transfer block 23. The second motor 20 drives the synchronous belt 22 to operate through the pulley, and when the synchronous belt 22 operates, the transfer block 23 moves up and down along the third guide rail 21, thereby realizing the up and down movement of the waste liquid suction component connected to the transfer block 23.
具体的，所述吸废液组件包括提升杆24、横臂25、针座26和吸液针27，所述提升杆24连接在所述转接块23的上方，所述横臂25连接在所述提升杆24的顶部，横臂25延伸至暗室机构III的上方，所述针座26连接在所述横臂25的末端，所述吸液针27连接在所述针座26的下方。所述吸液针27连接有排液管，所述排液管连接有吸液泵(附设结构未示出)。吸液针27吸取的废液通过排液管在吸液泵的作用下排出。Specifically, the waste liquid suction assembly includes a lifting rod 24, a cross arm 25, a needle seat 26 and a liquid suction needle 27, wherein the lifting rod 24 is connected to the top of the adapter block 23, the cross arm 25 is connected to the top of the lifting rod 24, the cross arm 25 extends to the top of the darkroom mechanism III, the needle seat 26 is connected to the end of the cross arm 25, and the liquid suction needle 27 is connected to the bottom of the needle seat 26. The liquid suction needle 27 is connected to a liquid discharge pipe, and the liquid discharge pipe is connected to a liquid suction pump (attached structure is not shown). The waste liquid sucked by the liquid suction needle 27 is discharged through the liquid discharge pipe under the action of the liquid suction pump.
本发明设有光路组件I、校验组件II、暗室机构III和废液吸取机构IV；光路组件I设有光电倍增管1、导光棒2和聚光杯3，光电倍增管1连接导光棒2，聚光杯3设置在导光棒2的侧部；校验组件II设有透镜4、光阑5、衰减片6和光源7，透镜4连接在聚光杯3的外侧，光阑5连接在透镜4的外侧，衰减片6连接光阑5的外侧，光源7连接在衰减片6的外侧，光源7发出的光依次经过衰减片6、光阑5和透镜4投射到光电倍增管1；暗室机构III设置在校验组件II的外侧，暗室机构III阻挡外界环境光线向校验组件II投射；废液吸取机构IV连接暗室机构III，废液吸取机构IV对聚光杯3内的废液进行吸取。本技术方案，未检测状态下遮光板9由牵拉弹簧12牵拉遮住导光棒2和光电倍增管1，当盛有待测物的反应杯28放进杯托15中时，第一电机17通过驱动带16带动杯托15沿第二导轨13移动，同时与遮光板9配合，推开遮光板9，通过底物接头19开始加注底物，光电倍增管1记录光子数量。检测结束后，第一电机17带动杯托15在第二导轨13上移动到废液吸取位，第二电机20带动吸废液组件在第三导轨21上移动到反应杯28杯底，吸走检测完的废液，第二电机20带动吸废液组件在第三导轨21上移动到高位，第一电机17带动杯托15在第二导轨13上移动到抓手位，现有的抓手模块抓取反应杯28丢到废料仓。本技术方案可以实现反应杯28的快速更换，又可以使检测物发出的瞬光或辉光有效的汇聚到光电倍增管1上，同时避免外界杂光的进入和干扰，检测结果准确度高。The present invention is provided with an optical path component I, a verification component II, a darkroom mechanism III and a waste liquid suction mechanism IV; the optical path component I is provided with a photomultiplier tube 1, a light guide rod 2 and a focusing cup 3, the photomultiplier tube 1 is connected to the light guide rod 2, and the focusing cup 3 is arranged on the side of the light guide rod 2; the verification component II is provided with a lens 4, an aperture 5, an attenuation plate 6 and a light source 7, the lens 4 is connected to the outside of the focusing cup 3, the aperture 5 is connected to the outside of the lens 4, the attenuation plate 6 is connected to the outside of the aperture 5, the light source 7 is connected to the outside of the attenuation plate 6, and the light emitted by the light source 7 is projected onto the photomultiplier tube 1 through the attenuation plate 6, the aperture 5 and the lens 4 in sequence; the darkroom mechanism III is arranged on the outside of the verification component II, and the darkroom mechanism III blocks the external environment light from being projected onto the verification component II; the waste liquid suction mechanism IV is connected to the darkroom mechanism III, and the waste liquid suction mechanism IV absorbs the waste liquid in the focusing cup 3. In the present technical solution, in the non-detection state, the light shielding plate 9 is pulled by the pulling spring 12 to shield the light guide rod 2 and the photomultiplier tube 1. When the reaction cup 28 containing the object to be detected is placed in the cup holder 15, the first motor 17 drives the cup holder 15 to move along the second guide rail 13 through the driving belt 16, and at the same time cooperates with the light shielding plate 9 to push the light shielding plate 9, and starts to add the substrate through the substrate connector 19, and the photomultiplier tube 1 records the number of photons. After the detection is completed, the first motor 17 drives the cup holder 15 to move to the waste liquid suction position on the second guide rail 13, and the second motor 20 drives the waste liquid suction component to move to the bottom of the reaction cup 28 on the third guide rail 21 to suck away the waste liquid after the detection, and the second motor 20 drives the waste liquid suction component to move to the high position on the third guide rail 21, and the first motor 17 drives the cup holder 15 to move to the gripper position on the second guide rail 13, and the existing gripper module grabs the reaction cup 28 and throws it into the waste bin. This technical solution can realize the rapid replacement of the reaction cup 28, and can effectively converge the instantaneous light or glow emitted by the detection object onto the photomultiplier tube 1, while avoiding the entry and interference of external stray light, and the detection result is highly accurate.
以上所述实施例的各技术特征可以进行任意的组合，为使描述简洁，未对上述实施例中的各个技术特征所有可能的组合都进行描述，然而，只要这些技术特征的组合不存在矛盾，都应当认为是本说明书记载的范围。The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.
以上所述实施例仅表达了本发明的几种实施方式，其描述较为具体和详细，但并不能因此而理解为对发明专利范围的限制。应当指出的是，对于本领域的普通技术人员来说，在不脱离本发明构思的前提下，还可以做出若干变形和改进，这些都属于本发明的保护范围。因此，本发明专利的保护范围应以所附权利要求为准。The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.
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