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CN110236522A - Health screening method, system and medical equipment based on single-lead electrocardiogram - Google Patents

Health screening method, system and medical equipment based on single-lead electrocardiogram Download PDF

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CN110236522A
CN110236522A CN201910454467.6A CN201910454467A CN110236522A CN 110236522 A CN110236522 A CN 110236522A CN 201910454467 A CN201910454467 A CN 201910454467A CN 110236522 A CN110236522 A CN 110236522A
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health
characteristic
lead electrocardiogram
sequence
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李秋平
王新安
赵天夏
丘常沛
彭晨
吴晓春
马洁茹
张思旭
席俊辉
何春舅
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Peking University Shenzhen Graduate School
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346Analysis of electrocardiograms
    • A61B5/349Detecting specific parameters of the electrocardiograph cycle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7246Details of waveform analysis using correlation, e.g. template matching or determination of similarity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

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Abstract

本发明涉及医疗系统技术领域,公开了一种基于单导联心电图的健康筛查方法、系统及医疗设备。所述基于单导联心电图的健康筛查方法包括:采集用户的单导联心电图;分析采集的单导联心电图中心电信号pRRx序列的特征数据;将分析的pRRx序列的特征数据与预先训练的健康检测模型进行特征匹配;以及根据特征匹配的结果生成用户的健康检测数据。本发明可基于便携式可实时监测的心电监测设备和健康筛查方法,可以对用户进行日常监测并做健康筛查,有利于及时发现用户潜在的大病风险,提醒用户及时去医院做相应检查、诊断和及时治疗。

The invention relates to the technical field of medical systems, and discloses a health screening method, system and medical equipment based on a single-lead electrocardiogram. The health screening method based on a single-lead electrocardiogram includes: collecting a user's single-lead electrocardiogram; analyzing the characteristic data of the collected single-lead electrocardiogram central electrical signal pRRx sequence; combining the characteristic data of the analyzed pRRx sequence with the pre-trained The health detection model performs feature matching; and generates the user's health detection data according to the result of the feature matching. The present invention can be based on a portable ECG monitoring device and a health screening method capable of real-time monitoring, and can perform daily monitoring and health screening on users, which is conducive to timely discovering potential serious disease risks of users, and reminding users to go to the hospital for corresponding examinations in time, diagnosis and timely treatment.

Description

基于单导联心电图的健康筛查方法、系统及医疗设备Health screening method, system and medical equipment based on single-lead electrocardiogram

技术领域technical field

本发明涉及医疗设备技术领域,尤其涉及一种基于单导联心电图的健康筛查方法、系统及医疗设备。The invention relates to the technical field of medical equipment, in particular to a single-lead electrocardiogram-based health screening method, system and medical equipment.

背景技术Background technique

目前医院的健康检测和诊断的流程复杂繁琐,通常需要单独排队进行多个项目的常规检查比如抽血、心电图等,整个健康数据检测的便捷性、舒适性、工作效率和用户体验不佳。且对于健康检查频次不高的用户容易遗漏病症,并错过预防和治疗的最佳时机。At present, the process of health detection and diagnosis in hospitals is complicated and cumbersome. Usually, it is necessary to queue up for routine inspections of multiple items such as blood drawing and electrocardiogram. The convenience, comfort, work efficiency and user experience of the whole health data detection are not good. And for users who do not have a high frequency of health checkups, it is easy to miss symptoms and miss the best time for prevention and treatment.

发明内容Contents of the invention

鉴于此,本发明提供一种基于单导联心电图的健康筛查方法、系统及医疗设备,解决现有健康检查的便捷性、舒适性、工作效率和用户体验不佳的技术问题。In view of this, the present invention provides a single-lead electrocardiogram-based health screening method, system, and medical equipment to solve the technical problems of poor convenience, comfort, work efficiency, and user experience in existing health checks.

根据本发明一个实施例,提供一种基于单导联心电图的健康筛查方法,包括:采集用户的单导联心电图;分析采集的单导联心电图中心电信号pRRx序列的特征数据;将分析的pRRx序列的特征数据与预先训练的健康检测模型进行特征匹配;以及根据特征匹配的结果生成用户的健康检测数据。According to one embodiment of the present invention, a health screening method based on a single-lead electrocardiogram is provided, including: collecting a user's single-lead electrocardiogram; analyzing the characteristic data of the collected single-lead electrocardiogram central electrical signal pRRx sequence; The feature data of the pRRx sequence is matched with the pre-trained health detection model; and the user's health detection data is generated according to the result of the feature matching.

优选的,所述的基于单导联心电图的健康筛查方法还包括训练健康检测模型,其进一步包括:采集不同用户不同时间的生理参数以及对应的单导联心电图;分析采集的单导联心电图中心电信号pRRx序列的特征数据;通过训练模型算法对采集的生理参数以及对应分析的pRRx序列的特征数据进行机器学习和训练,以生成pRRx序列的特征数据和生理参数对应关系的模型函数;以及基于生成的模型函数和采集的生理参数数据生成健康检测模型。Preferably, the health screening method based on a single-lead electrocardiogram also includes training a health detection model, which further includes: collecting physiological parameters of different users at different times and corresponding single-lead electrocardiograms; analyzing the collected single-lead electrocardiograms The characteristic data of the central electrical signal pRRx sequence; machine learning and training are performed on the collected physiological parameters and the correspondingly analyzed characteristic data of the pRRx sequence through the training model algorithm to generate a model function of the corresponding relationship between the characteristic data of the pRRx sequence and the physiological parameters; and A health detection model is generated based on the generated model function and the collected physiological parameter data.

优选的,在所述根据特征匹配的结果生成用户的健康检测数据之后,还包括:获取用户在多个时间的健康监测数据;分析获取的多个时间的健康监测数据以获取用户的健康趋势数据;以及根据获取的健康监测数据和健康趋势数据获取用户的健康检测报告。Preferably, after the user's health monitoring data is generated according to the result of feature matching, it also includes: acquiring the user's health monitoring data at multiple times; analyzing the acquired health monitoring data at multiple times to obtain the user's health trend data ; and obtain the user's health detection report according to the obtained health monitoring data and health trend data.

优选的,所述pRRx序列的特征数据为线性特征和熵值非线性特征、分形维数非线性特征中的一种或组合,其中所述线性特征为pRRx序列的平均值、标准差、相邻序列差值的均方根、相邻序列差值的标准差中的一种或组合,所述分形维数非线性特征为pRRx序列直方分布信息熵、pRRx序列功率谱直方分布信息熵和pRRx序列功率谱全频段分布信息熵中的一种或组合,所述分形维数非线性特征为结构函数法计算所得的分形维数、相关函数法计算所得的分形维数、变差法计算所得的分形维数和均方根法计算所得的分形维数中的一种或组合。Preferably, the feature data of the pRRx sequence is one or a combination of linear features, entropy nonlinear features, and fractal dimension nonlinear features, wherein the linear features are the average value, standard deviation, adjacent One or a combination of the root mean square of the sequence difference and the standard deviation of the adjacent sequence difference, the non-linear characteristics of the fractal dimension are pRRx sequence histogram distribution information entropy, pRRx sequence power spectrum histogram distribution information entropy and pRRx sequence One or a combination of the information entropy of the power spectrum full frequency band distribution, the nonlinear feature of the fractal dimension is the fractal dimension calculated by the structure function method, the fractal dimension calculated by the correlation function method, and the fractal dimension calculated by the variation method One or a combination of fractal dimension and fractal dimension calculated by root mean square method.

优选的,所述分析采集的单导联心电图中心电信号pRRx序列的特征数据,包括:计算采集的单导联心电图中心电信号相邻pRRx序列之差大于阈值x毫秒的数量与全部相邻pRRx序列的数量的比值;以及通过设置值不同的阈值x对应获取每一阈值x对应的比值而形成pRRx序列。Preferably, the analysis of the characteristic data of the collected single-lead electrocardiogram central electrical signal pRRx sequence includes: calculating the difference between the collected single-lead electrocardiographic central electrical signal adjacent pRRx sequences greater than the threshold x milliseconds and all adjacent pRRx The ratio of the number of sequences; and by setting different thresholds x correspondingly to obtain the ratio corresponding to each threshold x to form a pRRx sequence.

根据本发明的另一个实施例,还提供一种基于单导联心电图的健康筛查系统,包括:心电图采集装置,用于采集用户的单导联心电图;特征分析装置,用于分析所述心电图采集装置采集的单导联心电图中心电信号pRRx序列的特征数据;特征匹配装置,用于将所述特征分析装置分析的pRRx序列的特征数据与健康检测训练模型装置预先训练的健康检测模型进行特征匹配;以及检测数据生成装置,用于根据所述特征匹配装置特征匹配的结果生成用户的健康检测数据。According to another embodiment of the present invention, a health screening system based on a single-lead electrocardiogram is also provided, including: an electrocardiogram acquisition device for collecting a user's single-lead electrocardiogram; a feature analysis device for analyzing the electrocardiogram The feature data of the single-lead electrocardiogram central electrical signal pRRx sequence collected by the acquisition device; the feature matching device is used to perform characteristic data of the pRRx sequence analyzed by the feature analysis device and the health detection model pre-trained by the health detection training model device Matching; and detection data generating means for generating user's health detection data according to the result of feature matching by the feature matching means.

优选的,所述的基于单导联心电图的健康数据检测系统还包括健康检测训练模型装置,其进一步包括:数据采集单元,用于采集不同用户不同时间的生理参数以及对应的单导联心电图;数据分析单元,用于分析所述数据采集单元采集的单导联心电图中心电信号pRRx序列的特征数据;模型函数训练单元,用于通过训练模型算法对所述数据采集单元采集的生理参数以及所述数据分析单元对应分析的pRRx序列的特征数据进行机器学习和训练,以生成pRRx序列的特征数据和生理参数对应关系的模型函数;以及健康检测模型生成单元,用于基于所述模型函数训练单元生成的模型函数和所述数据采集单元采集的生理参数数据生成健康检测模型。Preferably, the health data detection system based on a single-lead electrocardiogram also includes a health detection training model device, which further includes: a data collection unit for collecting physiological parameters of different users at different times and corresponding single-lead electrocardiograms; The data analysis unit is used to analyze the characteristic data of the single-lead electrocardiogram central electrical signal pRRx sequence collected by the data collection unit; the model function training unit is used to use the training model algorithm to collect the physiological parameters and the obtained data collection unit. The data analysis unit performs machine learning and training on the characteristic data of the pRRx sequence corresponding to the analysis, so as to generate a model function of the corresponding relationship between the characteristic data of the pRRx sequence and the physiological parameters; and a health detection model generation unit for training the unit based on the model function The generated model function and the physiological parameter data collected by the data collection unit generate a health detection model.

优选的,所述的基于单导联心电图的健康数据检测系统还包括检测报告生成装置,其进一步包括:数据获取单元,用于获取用户在多个时间的健康监测数据;趋势分析单元,用于分析所述数据获取单元获取的多个时间的健康监测数据以获取用户的健康趋势数据;以及检测报告生成单元,用于根据所述数据获取单元获取的健康监测数据和所述趋势分析单元分析的健康趋势数据获取用户的健康检测报告。Preferably, the single-lead electrocardiogram-based health data detection system also includes a detection report generation device, which further includes: a data acquisition unit, used to acquire health monitoring data of the user at multiple times; a trend analysis unit, used for Analyzing the health monitoring data obtained by the data acquisition unit at multiple times to obtain the user's health trend data; and a detection report generation unit for analyzing the health monitoring data obtained by the data acquisition unit and the trend analysis unit The health trend data obtains the user's health detection report.

优选的,所述pRRx序列的特征数据为线性特征和熵值非线性特征、分形维数非线性特征中的一种或组合,其中所述线性特征为pRRx序列的平均值、标准差、相邻序列差值的均方根、相邻序列差值的标准差中的一种或组合,所述分形维数非线性特征为pRRx序列直方分布信息熵、pRRx序列功率谱直方分布信息熵和pRRx序列功率谱全频段分布信息熵中的一种或组合,所述分形维数非线性特征为结构函数法计算所得的分形维数、相关函数法计算所得的分形维数、变差法计算所得的分形维数和均方根法计算所得的分形维数中的一种或组合。Preferably, the feature data of the pRRx sequence is one or a combination of linear features, entropy nonlinear features, and fractal dimension nonlinear features, wherein the linear features are the average value, standard deviation, adjacent One or a combination of the root mean square of the sequence difference and the standard deviation of the adjacent sequence difference, the non-linear characteristics of the fractal dimension are pRRx sequence histogram distribution information entropy, pRRx sequence power spectrum histogram distribution information entropy and pRRx sequence One or a combination of the information entropy of the power spectrum full frequency band distribution, the nonlinear feature of the fractal dimension is the fractal dimension calculated by the structure function method, the fractal dimension calculated by the correlation function method, and the fractal dimension calculated by the variation method One or a combination of fractal dimension and fractal dimension calculated by root mean square method.

根据本发明又一个实施例,还提供一种医疗设备,所述医疗设备包括上述的基于单导联心电图的健康筛查系统。According to still another embodiment of the present invention, there is also provided a medical device, which includes the above-mentioned health screening system based on a single-lead electrocardiogram.

本发明提供的基于单导联心电图的健康筛查方法、系统及医疗设备,采集用户的单导联心电图;分析采集的单导联心电图中心电信号pRRx序列的特征数据;将分析的pRRx序列的特征数据与预先训练的健康检测模型进行特征匹配;以及根据特征匹配的结果生成用户的健康检测数据。本发明可基于便携式可实时监测的心电监测设备和健康筛查方法,可以对用户进行日常监测并做健康筛查,有利于及时发现用户潜在的大病风险,提醒用户及时去医院做相应检查、诊断和及时治疗。The health screening method, system and medical equipment based on the single-lead electrocardiogram provided by the present invention collect the user's single-lead electrocardiogram; analyze the characteristic data of the collected single-lead electrocardiogram central electrical signal pRRx sequence; the analyzed pRRx sequence The feature data is matched with the pre-trained health detection model; and the user's health detection data is generated according to the result of the feature matching. The present invention can be based on a portable ECG monitoring device and a health screening method capable of real-time monitoring, and can perform daily monitoring and health screening on users, which is conducive to timely discovering potential serious disease risks of users, and reminding users to go to the hospital for corresponding examinations in time, diagnosis and timely treatment.

附图说明Description of drawings

为了更清楚地说明本发明实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单的介绍。显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings that need to be used in the description of the embodiments. Apparently, the drawings in the following description are only some embodiments of the present invention, and those skilled in the art can obtain other drawings according to these drawings without creative efforts.

图1为本发明一个实施例中基于单导联心电图的健康筛查方法的流程示意图。FIG. 1 is a schematic flowchart of a health screening method based on a single-lead electrocardiogram in an embodiment of the present invention.

图2为本发明一个实施例中分析pRRx序列的特征数据的流程示意图。Fig. 2 is a schematic flow chart of analyzing characteristic data of pRRx sequence in one embodiment of the present invention.

图3为本发明一个实施例中训练健康检测模型的流程示意图。Fig. 3 is a schematic flow chart of training a health detection model in an embodiment of the present invention.

图4为本发明一个实施例中生成用户的健康检测报告的流程示意图。Fig. 4 is a schematic flowchart of generating a user's health inspection report in an embodiment of the present invention.

图5为本发明另一个实施例中基于单导联心电图的健康数据检测系统的结构示意图。Fig. 5 is a schematic structural diagram of a health data detection system based on a single-lead electrocardiogram in another embodiment of the present invention.

图6为本发明另一个实施例中健康检测训练模型装置的结构示意图。Fig. 6 is a schematic structural diagram of a health detection training model device in another embodiment of the present invention.

图7为本发明另一个实施例中检测报告生成装置的结构示意图。Fig. 7 is a schematic structural diagram of a detection report generating device in another embodiment of the present invention.

图8为本发明再一个实施例中医疗设备的结构示意图。Fig. 8 is a schematic structural diagram of a medical device in another embodiment of the present invention.

具体实施方式Detailed ways

下面结合附图和具体实施方式对本发明的技术方案作进一步更详细的描述。显然,所描述的实施例仅仅是本发明的一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动的前提下所获得的所有其他实施例,都应属于本发明保护的范围。The technical solutions of the present invention will be further described in more detail in conjunction with the accompanying drawings and specific embodiments. Apparently, the described embodiments are only some of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

在本发明的描述中,需要理解的是,术语“第一”、“第二”等仅用于描述目的,而不能理解为指示或暗示相对重要性。在本发明的描述中,需要说明的是,除非另有明确的规定和限定,术语“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连。对于本领域的普通技术人员而言,可以结合具体情况理解上述术语在本发明中的具体含义。此外,在本发明的描述中,除非另有说明,“多个”的含义是两个或两个以上。In the description of the present invention, it should be understood that the terms "first", "second" and so on are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance. In the description of the present invention, it should be noted that unless otherwise specified and limited, the terms "connected" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral Ground connection; it can be mechanical connection or electrical connection; it can be direct connection or indirect connection through an intermediary. Those of ordinary skill in the art can understand the specific meanings of the above terms in the present invention in combination with specific situations. In addition, in the description of the present invention, unless otherwise specified, "plurality" means two or more.

流程图中或在此以其他方式描述的任何过程或方法描述可以被理解为,表示包括一个或更多个用于实现特定逻辑功能或过程的步骤的可执行指令的代码的模块、片段或部分,并且本发明的优选实施方式的范围包括另外的实现,其中可以不按所示出或讨论的顺序,包括根据所涉及的功能按基本同时的方式或按相反的顺序,来执行功能,这应被本发明的实施例所属技术领域的技术人员所理解。Any process or method descriptions in flowcharts or otherwise described herein may be understood to represent modules, segments or portions of code comprising one or more executable instructions for implementing specific logical functions or steps of the process , and the scope of preferred embodiments of the invention includes alternative implementations in which functions may be performed out of the order shown or discussed, including substantially concurrently or in reverse order depending on the functions involved, which shall It is understood by those skilled in the art to which the embodiments of the present invention pertain.

图1为本发明一个实施例中基于单导联心电图的健康数据检测方法的流程示意图。如图所示,所述基于单导联心电图的健康筛查方法,包括:Fig. 1 is a schematic flowchart of a health data detection method based on a single-lead electrocardiogram in an embodiment of the present invention. As shown in the figure, the health screening method based on the single-lead electrocardiogram includes:

步骤S101:采集用户的单导联心电图。Step S101: collecting a single-lead electrocardiogram of a user.

在本实施例中,当需要对用户进行健康数据检测时,可选用通用的单导联心电信号采集设备采集用户的单导联心电图,采集过程简单而无创伤,无需排队进行各个项目的常规检查,提升了健康检查的便捷性、舒适性、工作效率和用户体验。In this embodiment, when it is necessary to detect the user's health data, a general-purpose single-lead ECG signal acquisition device can be used to collect the user's single-lead ECG. Check, improving the convenience, comfort, work efficiency and user experience of health check.

步骤S102:分析采集的单导联心电图中心电信号pRRx序列的特征数据。Step S102: analyzing the characteristic data of the collected single-lead ECG central electrical signal pRRx sequence.

在本实施例中,进一步分析采集的单导联心电图中心电信号pRRx序列的特征数据。参见图2,所述分析采集的单导联心电图中心电信号pRRx序列的特征数据,包括:In this embodiment, the characteristic data of the collected single-lead ECG central electrical signal pRRx sequence are further analyzed. Referring to Fig. 2, the characteristic data of the single-lead electrocardiogram central electrical signal pRRx sequence of described analysis collection, include:

步骤S201:计算采集的单导联心电图中心电信号相邻pRRx序列之差大于阈值x毫秒的数量与全部相邻pRRx序列的数量的比值。Step S201: Calculate the ratio of the number of adjacent pRRx sequences whose central electrical signal of the collected single-lead ECG is greater than the threshold x milliseconds to the number of all adjacent pRRx sequences.

步骤S202:通过设置值不同的阈值x对应获取每一阈值x对应的比值而形成pRRx序列。Step S202: By setting thresholds x with different values correspondingly, obtaining the ratio corresponding to each threshold x to form a pRRx sequence.

在本实施例中,首先计算采集的单导联心电图中心电信号相邻pRRx序列之差大于阈值x毫秒的数量与全部相邻pRRx序列的数量的比值,然后通过设置值不同的阈值x对应获取每一阈值x对应的比值而形成pRRx序列,其计算公式为:In this embodiment, first calculate the ratio of the number of adjacent pRRx sequences whose difference between the collected single-lead ECG central electrical signal is greater than the threshold x milliseconds to the number of all adjacent pRRx sequences, and then obtain corresponding values by setting different thresholds x The ratio corresponding to each threshold x forms the pRRx sequence, and its calculation formula is:

在本实施例中,所述pRRx序列的特征数据为线性特征和熵值非线性特征、分形维数非线性特征中的一种或组合。In this embodiment, the feature data of the pRRx sequence is one or a combination of linear features, entropy nonlinear features, and fractal dimension nonlinear features.

所述线性特征为pRRx序列的平均值AVRR、标准差SDRR、相邻序列差值的均方根rMSSD、相邻序列差值的标准差SDSD中的一种或组合。The linear feature is one or a combination of the average value AVRR, the standard deviation SDRR of the pRRx sequence, the root mean square rMSSD of the difference between adjacent sequences, and the standard deviation SDSD of the difference between adjacent sequences.

所述分形维数非线性特征为pRRx序列直方分布信息熵、pRRx序列功率谱直方分布信息熵和pRRx序列功率谱全频段分布信息熵中的一种或组合。The non-linear feature of fractal dimension is one or a combination of information entropy of pRRx sequence histogram distribution, pRRx sequence power spectrum histogram distribution information entropy and pRRx sequence power spectrum full frequency band distribution information entropy.

对于概率分布函数p(x)的随机变量集A,熵的定义如式(2)所示:For the random variable set A of the probability distribution function p(x), the definition of entropy is shown in formula (2):

H(A)=-∑pA(x)logpA(x) (2)H(A)=-∑p A (x)logp A (x) (2)

可以获得的特征包括:Available features include:

(1)pRRx序列直方分布信息熵Sdh是对pRRx序列的数值分布信息熵;(1) pRRx sequence histogram distribution information entropy S dh is the numerical distribution information entropy of pRRx sequence;

(2)pRRx序列功率谱直方分布信息熵Sph是对pRRx序列进行离散傅里叶变换得到功率谱,然后根据功率谱序列的数值分布计算其信息熵;(2) The pRRx sequence power spectrum histogram distribution information entropy S ph is to perform discrete Fourier transform on the pRRx sequence to obtain the power spectrum, and then calculate its information entropy according to the numerical distribution of the power spectrum sequence;

(3)pRRx序列功率谱全频段分布信息熵Spf是对pRRx序列进行离散傅里叶变换得到功率谱,在全频段[fs/N,fs/2](信号的采样频率为fs,采样点数为N)内插入i-1个分点f1,f2,...,fm-1,将全频段分割成i个子频段。把每个频段内的功率密度之和作为该频段的功率密度,则得到m个功率密度。将这i个功率密度归一化得到每个频段出现的概率pi,则∑ipi=1,相应的功率谱全频段熵如式(3)所示:(3) pRRx sequence power spectrum full frequency distribution information entropy S pf is the power spectrum obtained by discrete Fourier transform of pRRx sequence, in the whole frequency band [f s /N, f s /2] (the sampling frequency of the signal is f s , the number of sampling points is N), inserting i-1 sub-points f 1 , f 2 , ..., f m-1 to divide the whole frequency band into i sub-frequency bands. Taking the sum of the power densities in each frequency band as the power density of the frequency band, m power densities are obtained. Normalize the i power density to obtain the probability p i of each frequency band, then ∑ i p i =1, and the corresponding entropy of the entire frequency band of the power spectrum is shown in formula (3):

在本实施例中,所述分形维数非线性特征为结构函数法计算所得的分形维数、相关函数法计算所得的分形维数、变差法计算所得的分形维数和均方根法计算所得的分形维数中的一种或组合。In this embodiment, the non-linear feature of the fractal dimension is the fractal dimension calculated by the structure function method, the fractal dimension calculated by the correlation function method, the fractal dimension calculated by the variation method and the root mean square method. One or a combination of the resulting fractal dimensions.

在本实施例中,对每段心电信号的pRRx序列进行非线性分析,也可以采用下面四种分形维数计算分析方法可以得到如下的特征指标:In this embodiment, the pRRx sequence of each segment of ECG is analyzed nonlinearly, and the following four fractal dimension calculation and analysis methods can also be used to obtain the following characteristic indicators:

(1)结构函数法计算所得的分形维数Dsf,其中,结构函数法是指对于给定的序列z(x),定义增量方差为结构函数,其关系为:(1) The fractal dimension D sf calculated by the structural function method, wherein the structural function method refers to defining the incremental variance as a structural function for a given sequence z(x), and its relationship is:

对于若干个标度τ,对序列z(x)的离散值计算出相应的S(τ),然后画出logS(τ)-logτ的函数曲线,在无标度区进行线性拟合,得到斜率α,则对应分形维数Dsf与斜率α的转化关系如式(5)所示:For several scales τ, calculate the corresponding S(τ) for the discrete values of the sequence z(x), then draw the function curve of logS(τ)-logτ, and perform linear fitting in the scale-free area to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D sf and the slope α is shown in formula (5):

(2)相关函数法计算所得的分形维数Dcf,其中,相关函数法是指对于给定的序列z(x),相关函数C(τ)定义为式(6)所示:(2) The fractal dimension D cf calculated by the correlation function method, where the correlation function method means that for a given sequence z(x), the correlation function C(τ) is defined as shown in formula (6):

C(τ)=AVE(z(x+τ)*z(x)),τ=1,2,3,...,N-1 (6)C(τ)=AVE(z(x+τ)*z(x)), τ=1, 2, 3, ..., N-1 (6)

其中,AVE(·)表示平均,τ表示两点距离。此时相关函数为幂型,由于不存在特征长度,则分布为分形,有C(τ)ατ。这时,画出logC(τ)-logτ的函数曲线,在无标度区进行线性拟合,得到斜率α,则对应分形维数Dcf与斜率α的转化关系如式(7)所示:Among them, AVE(·) represents the average, and τ represents the distance between two points. At this time, the correlation function is a power type, and since there is no characteristic length, the distribution is a fractal, with C(τ)ατ . At this time, draw the function curve of logC(τ)-logτ, and perform linear fitting in the scale-free area to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D cf and the slope α is shown in formula (7):

Dcf=2-α (7)D cf =2-α (7)

(3)变差法计算所得的分形维数Dvm,其中,变差法用宽为τ的矩形框首尾相接的将分形曲线覆盖起来,令第i个框内曲线的最大值和最小值之差为H(i),即为矩形的高度。将所有矩形的高和宽相乘得到总面积S(τ)。改变τ的大小,得到一系列的S(τ)。如式(8)所示:(3) The fractal dimension D vm calculated by the variation method, wherein, the variation method covers the fractal curve with a rectangular frame with a width of τ connected end to end, so that the maximum value and minimum value of the curve in the i-th frame The difference is H(i), which is the height of the rectangle. Multiply the height and width of all rectangles to get the total area S(τ). Change the size of τ to get a series of S(τ). As shown in formula (8):

画出log N(τ)-logτ的函数曲线,在无标度区进行线性拟合得到斜率α,则对应分形维数Dvm与斜率α的转化关系如式(7)所示。Draw the function curve of log N(τ)-logτ, and perform linear fitting in the scale-free region to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D vm and slope α is shown in formula (7).

(4)均方根法计算所得的分形维数Drms,其中,均方根法用宽为τ的矩形框首尾相接的将分形曲线覆盖起来,令第i个框内曲线的最大值和最小值之差为H(i),即为矩形的高度。计算这些矩形高度的均方根值S(τ)。改变τ的大小,得到一系列的S(τ)。画出log S(τ)-log τ的函数曲线,在无标度区进行线性拟合得到斜率α,则对应分形维数Drms与斜率α的转化关系如式(7)所示。(4) The fractal dimension D rms calculated by the root mean square method, wherein the root mean square method covers the fractal curve with a rectangular frame with a width τ connected end to end, so that the maximum value of the curve in the i-th frame and The minimum difference is H(i), which is the height of the rectangle. Compute the root mean square value S(τ) of the heights of these rectangles. Change the size of τ to get a series of S(τ). Draw the function curve of log S(τ)-log τ, and perform linear fitting in the scale-free region to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D rms and the slope α is shown in formula (7).

步骤S103:将分析的pRRx序列的特征数据与预先训练的健康检测模型进行特征匹配。Step S103: performing feature matching on the analyzed feature data of the pRRx sequence and the pre-trained health detection model.

参见图3,在进行特征匹配之前,需要预先训练健康检测模型。所述训练健康检测模型,包括:Referring to Figure 3, before feature matching, the health detection model needs to be pre-trained. The training health detection model includes:

步骤S301:采集不同用户不同时间的生理参数以及对应的单导联心电图。Step S301: collecting physiological parameters and corresponding single-lead electrocardiograms of different users at different times.

步骤S302:分析采集的单导联心电图中心电信号pRRx序列的特征数据。Step S302: analyzing the characteristic data of the collected single-lead ECG central electrical signal pRRx sequence.

步骤S303:通过训练模型算法对采集的生理参数以及对应分析的pRRx序列的特征数据进行机器学习和训练,以生成pRRx序列的特征数据和生理参数对应关系的模型函数。Step S303: Carry out machine learning and training on the collected physiological parameters and correspondingly analyzed characteristic data of the pRRx sequence through the training model algorithm to generate a model function of the corresponding relationship between the characteristic data of the pRRx sequence and the physiological parameters.

步骤S304:基于生成的模型函数和采集的生理参数数据生成健康检测模型。Step S304: Generate a health detection model based on the generated model function and the collected physiological parameter data.

在本实施例中,首先采集不同用户不同时间的生理参数以及对应的单导联心电图,然后分析采集的单导联心电图中心电信号pRRx序列的特征数据,再通过训练模型算法对采集的生理参数以及对应分析的pRRx序列的特征数据进行机器学习和训练,以生成pRRx序列的特征数据和生理参数对应关系的模型函数,最终基于生成的模型函数和采集的生理参数数据生成健康检测模型。In this embodiment, first collect the physiological parameters of different users at different times and the corresponding single-lead electrocardiogram, then analyze the characteristic data of the collected single-lead electrocardiogram center electrical signal pRRx sequence, and then use the training model algorithm to analyze the collected physiological parameters And machine learning and training are performed on the characteristic data of the corresponding analyzed pRRx sequence to generate a model function of the corresponding relationship between the characteristic data of the pRRx sequence and physiological parameters, and finally generate a health detection model based on the generated model function and the collected physiological parameter data.

其中,所述生理参数包括但不限于:年龄、性别、病史、血糖、体重指数、血压、尿常规、血钾、血红蛋白、血常规、血肌酐、血脂、尿酸、血流动力学监测结果、超声心动图或者颈动脉超声、尿蛋白、朐片、心电图、眼底、吸烟史、心内电生理检查结果、冠状动脉造影结果、疾病类型、阶段、并发症数量及严重程度等。Among them, the physiological parameters include but are not limited to: age, gender, medical history, blood sugar, body mass index, blood pressure, urine routine, blood potassium, hemoglobin, blood routine, blood creatinine, blood lipids, uric acid, hemodynamic monitoring results, ultrasound Cardiogram or carotid ultrasound, urine protein, X-ray film, electrocardiogram, fundus, smoking history, intracardiac electrophysiological examination results, coronary angiography results, disease type, stage, number and severity of complications, etc.

在分析获取到用户的特征数据和健康检测模型后,进一步将分析获取的特征数据与预先训练的健康检测模型进行特征匹配。具体的,将分析获取的所有特征数据逐项与预先训练的健康检测模型中的所有特征模板进行相似度匹配,当发现特定特征数据与其中一个特征模板相似度超过预设阈值时,判断两者特征匹配成功,否则判断两者特征匹配失败。After analyzing and obtaining the user's characteristic data and the health detection model, further perform feature matching on the analyzed and obtained characteristic data and the pre-trained health detection model. Specifically, all the feature data acquired by analysis are matched item by item with all feature templates in the pre-trained health detection model. When the similarity between specific feature data and one of the feature templates is found to exceed the preset threshold, the The feature matching is successful, otherwise it is judged that the feature matching between the two fails.

步骤S104:根据特征匹配的结果生成用户的健康检测数据。Step S104: Generate user's health detection data according to the result of feature matching.

在本实施例中,当分析获取的特征数据与预先训练的健康检测模型中特定特征模板匹配时,根据所述健康检测模型中心电信号pRRx序列的特征数据和生理参数对应关系的模型函数,可输出所述特定特征模板对应的生理参数数据而生成当前用户身体健康的检测数据,可方便快捷地基于健康检测数据、对用户的健康状况进行评估,对有疾病风险的情况进行筛查,提醒用户及时就医确诊并在最佳时机进行治疗。In this embodiment, when the characteristic data acquired by analysis matches the specific characteristic template in the pre-trained health detection model, according to the model function of the corresponding relationship between the characteristic data of the central electrical signal pRRx sequence of the health detection model and the physiological parameters, it can be Output the physiological parameter data corresponding to the specific feature template to generate the detection data of the current user's health, which can conveniently and quickly evaluate the user's health status based on the health detection data, screen the situation with disease risk, and remind the user Seek medical diagnosis in time and treat at the best time.

参见图4,在另一些实施例中,在上述实施例的基础上,可进一步生成用户的健康检测报告。所述生成用户的健康检测报告,包括:Referring to FIG. 4 , in some other embodiments, on the basis of the above embodiments, a user's health detection report may be further generated. The user's health detection report generated includes:

步骤S401:获取用户在多个时间的健康监测数据。Step S401: Obtain the user's health monitoring data at multiple times.

步骤S402:分析获取的多个时间的健康监测数据以获取用户的健康趋势数据。Step S402: Analyze the acquired health monitoring data at multiple times to obtain the user's health trend data.

步骤S403:根据获取的健康监测数据和健康趋势数据获取用户的健康检测报告。Step S403: Obtain the user's health detection report according to the obtained health monitoring data and health trend data.

在本实施例中,针对同一用户可在多个时间进行单导联心电图检测,获取用户在多个时间的健康监测数据,分析获取的多个时间的健康监测数据以获取用户的健康趋势数据,并根据获取的健康监测数据和健康趋势数据获取用户的健康检测报告,可基于便携式可实时监测的心电监测设备和健康筛查方法,可以对用户进行日常监测并做健康筛查,有利于及时发现用户潜在的大病风险,提醒用户及时去医院做相应检查、诊断和及时治疗。In this embodiment, single-lead ECG detection can be performed on the same user at multiple times, the user's health monitoring data at multiple times can be obtained, and the health monitoring data obtained at multiple times can be analyzed to obtain the user's health trend data. And according to the obtained health monitoring data and health trend data, the user's health detection report can be obtained. Based on the portable ECG monitoring equipment and health screening method that can be monitored in real time, it can conduct daily monitoring and health screening for users, which is conducive to timely Discover the user's potential risk of serious illness, and remind the user to go to the hospital for corresponding examination, diagnosis and timely treatment.

图5为本发明另一个实施例中基于单导联心电图的健康数据检测系统的结构示意图。基于上述方法实施例,本实施例的基于单导联心电图的健康数据检测系统100,包括心电图采集装置10、特征分析装置20、特征匹配装置30和检测数据生成装置40。Fig. 5 is a schematic structural diagram of a health data detection system based on a single-lead electrocardiogram in another embodiment of the present invention. Based on the above method embodiments, the single-lead ECG-based health data detection system 100 of this embodiment includes an ECG acquisition device 10 , a feature analysis device 20 , a feature matching device 30 and a detection data generation device 40 .

在本实施例中,当需要对用户进行健康数据检测时,可通过所述心电图采集装置10比如通用的单导联心电信号采集设备采集用户的单导联心电图,采集过程简单而无创伤,无需排队进行各个项目的常规检查,提升了健康检查的便捷性、舒适性、工作效率和用户体验。In this embodiment, when it is necessary to detect the user's health data, the user's single-lead ECG can be collected by the electrocardiogram acquisition device 10, such as a general-purpose single-lead ECG signal acquisition device, and the acquisition process is simple and non-invasive. There is no need to queue up for routine inspections of various items, which improves the convenience, comfort, work efficiency and user experience of health inspections.

在本实施例中,所述特征分析装置20进一步分析所述心电图采集装置10采集的单导联心电图中心电信号pRRx序列的特征数据。所述特征分析装置20包括首先计算采集的单导联心电图中心电信号相邻pRRx序列之差大于阈值x毫秒的数量与全部相邻pRRx序列的数量的比值,然后通过设置值不同的阈值x对应获取每一阈值x对应的比值而形成pRRx序列,其计算公式为:In this embodiment, the characteristic analysis device 20 further analyzes the characteristic data of the central electrical signal pRRx sequence of the single-lead electrocardiogram collected by the electrocardiogram collection device 10 . The feature analysis device 20 includes first calculating the ratio of the number of adjacent pRRx sequences in which the difference between the collected single-lead electrocardiogram central electrical signal is greater than the threshold x milliseconds to the number of all adjacent pRRx sequences, and then by setting different thresholds x to correspond to The ratio corresponding to each threshold x is obtained to form a pRRx sequence, and its calculation formula is:

在本实施例中,所述pRRx序列的特征数据为线性特征和熵值非线性特征、分形维数非线性特征中的一种或组合。In this embodiment, the feature data of the pRRx sequence is one or a combination of linear features, entropy nonlinear features, and fractal dimension nonlinear features.

所述线性特征为pRRx序列的平均值AVRR、标准差SDRR、相邻序列差值的均方根rMSSD、相邻序列差值的标准差SDSD中的一种或组合。The linear feature is one or a combination of the average value AVRR, the standard deviation SDRR of the pRRx sequence, the root mean square rMSSD of the difference between adjacent sequences, and the standard deviation SDSD of the difference between adjacent sequences.

所述分形维数非线性特征为pRRx序列直方分布信息熵、pRRx序列功率谱直方分布信息熵和pRRx序列功率谱全频段分布信息熵中的一种或组合。The non-linear feature of fractal dimension is one or a combination of information entropy of pRRx sequence histogram distribution, pRRx sequence power spectrum histogram distribution information entropy and pRRx sequence power spectrum full frequency band distribution information entropy.

对于概率分布函数p(x)的随机变量集A,熵的定义如式(2)所示:For the random variable set A of the probability distribution function p(x), the definition of entropy is shown in formula (2):

H(A)=-∑pA(x)log pA(x) (2)H(A)=-∑p A (x)log p A (x) (2)

可以获得的特征包括:Available features include:

(4)pRRx序列直方分布信息熵Sdh是对pRRx序列的数值分布信息熵;(4) pRRx sequence histogram distribution information entropy S dh is the numerical distribution information entropy of pRRx sequence;

(5)pRRx序列功率谱直方分布信息熵Sph是对pRRx序列进行离散傅里叶变换得到功率谱,然后根据功率谱序列的数值分布计算其信息熵;(5) The pRRx sequence power spectrum histogram distribution information entropy S ph is to perform discrete Fourier transform on the pRRx sequence to obtain the power spectrum, and then calculate its information entropy according to the numerical distribution of the power spectrum sequence;

(6)pRRx序列功率谱全频段分布信息熵Spf是对pRRx序列进行离散傅里叶变换得到功率谱,在全频段[fs/N,fs/2](信号的采样频率为fs,采样点数为N)内插入i-1个分点f1,f2,...,fm-1,将全频段分割成i个子频段。把每个频段内的功率密度之和作为该频段的功率密度,则得到m个功率密度。将这i个功率密度归一化得到每个频段出现的概率pi,则∑ipi=1,相应的功率谱全频段熵如式(3)所示:(6) pRRx sequence power spectrum full frequency distribution information entropy S pf is the power spectrum obtained by discrete Fourier transform of pRRx sequence, in the whole frequency band [f s /N, f s /2] (the sampling frequency of the signal is f s , the number of sampling points is N), inserting i-1 sub-points f 1 , f 2 , ..., f m-1 to divide the whole frequency band into i sub-frequency bands. Taking the sum of the power densities in each frequency band as the power density of the frequency band, m power densities are obtained. Normalize the i power density to obtain the probability p i of each frequency band, then ∑ i p i =1, and the corresponding entropy of the entire frequency band of the power spectrum is shown in formula (3):

在本实施例中,所述分形维数非线性特征为结构函数法计算所得的分形维数、相关函数法计算所得的分形维数、变差法计算所得的分形维数和均方根法计算所得的分形维数中的一种或组合。In this embodiment, the non-linear feature of the fractal dimension is the fractal dimension calculated by the structure function method, the fractal dimension calculated by the correlation function method, the fractal dimension calculated by the variation method and the root mean square method. One or a combination of the resulting fractal dimensions.

在本实施例中,对每段心电信号的pRRx序列进行非线性分析,也可以采用下面四种分形维数计算分析方法可以得到如下的特征指标:In this embodiment, the pRRx sequence of each segment of ECG is analyzed nonlinearly, and the following four fractal dimension calculation and analysis methods can also be used to obtain the following characteristic indicators:

(5)结构函数法计算所得的分形维数Dsf,其中,结构函数法是指对于给定的序列z(x),定义增量方差为结构函数,其关系为:(5) The fractal dimension D sf calculated by the structural function method, wherein the structural function method refers to defining the incremental variance as a structural function for a given sequence z(x), and its relationship is:

对于若干个标度τ,对序列z(x)的离散值计算出相应的S(τ),然后画出log S(τ)-logτ的函数曲线,在无标度区进行线性拟合,得到斜率α,则对应分形维数Dsf与斜率α的转化关系如式(5)所示:For several scales τ, the corresponding S(τ) is calculated for the discrete values of the sequence z(x), and then the function curve of log S(τ)-logτ is drawn, and linear fitting is carried out in the scale-free region to obtain The slope α, the conversion relationship between the corresponding fractal dimension D sf and the slope α is shown in formula (5):

(6)相关函数法计算所得的分形维数Dcf,其中,相关函数法是指对于给定的序列z(x),相关函数C(τ)定义为式(6)所示:(6) The fractal dimension D cf calculated by the correlation function method, where the correlation function method means that for a given sequence z(x), the correlation function C(τ) is defined as shown in formula (6):

C(τ)=AVE(z(x+τ)*z(x)),τ=1,2,3,...,N-1 (6)C(τ)=AVE(z(x+τ)*z(x)), τ=1, 2, 3, ..., N-1 (6)

其中,AVE(·)表示平均,τ表示两点距离。此时相关函数为幂型,由于不存在特征长度,则分布为分形,有C(τ)ατ。这时,画出log C(τ)-logτ的函数曲线,在无标度区进行线性拟合,得到斜率α,则对应分形维数Dcf与斜率α的转化关系如式(7)所示:Among them, AVE(·) represents the average, and τ represents the distance between two points. At this time, the correlation function is a power type, and since there is no characteristic length, the distribution is a fractal, with C(τ)ατ . At this time, draw the function curve of log C(τ)-logτ, and perform linear fitting in the scale-free area to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D cf and the slope α is shown in formula (7) :

Dcf=2-α (7)D cf =2-α (7)

(7)变差法计算所得的分形维数Dvm,其中,变差法用宽为τ的矩形框首尾相接的将分形曲线覆盖起来,令第i个框内曲线的最大值和最小值之差为H(i),即为矩形的高度。将所有矩形的高和宽相乘得到总面积S(τ)。改变τ的大小,得到一系列的S(τ)。如式(8)所示:(7) The fractal dimension D vm calculated by the variation method, wherein, the variation method covers the fractal curve with a rectangular frame with a width of τ connected end to end, so that the maximum value and minimum value of the curve in the i-th frame The difference is H(i), which is the height of the rectangle. Multiply the height and width of all rectangles to get the total area S(τ). Change the size of τ to get a series of S(τ). As shown in formula (8):

画出log N(τ)-logτ的函数曲线,在无标度区进行线性拟合得到斜率α,则对应分形维数Dvm与斜率α的转化关系如式(7)所示。Draw the function curve of log N(τ)-logτ, and perform linear fitting in the scale-free region to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D vm and slope α is shown in formula (7).

(8)均方根法计算所得的分形维数Drms,其中,均方根法用宽为τ的矩形框首尾相接的将分形曲线覆盖起来,令第i个框内曲线的最大值和最小值之差为H(i),即为矩形的高度。计算这些矩形高度的均方根值S(τ)。改变τ的大小,得到一系列的S(τ)。画出log S(τ)-logτ的函数曲线,在无标度区进行线性拟合得到斜率α,则对应分形维数Drms与斜率α的转化关系如式(7)所示。(8) The fractal dimension D rms calculated by the root mean square method, wherein the root mean square method covers the fractal curve with a rectangular frame with a width of τ connected end to end, so that the maximum value of the curve in the i-th frame and The minimum difference is H(i), which is the height of the rectangle. Compute the root mean square value S(τ) of the heights of these rectangles. Change the size of τ to get a series of S(τ). Draw the function curve of log S(τ)-logτ, and perform linear fitting in the scale-free region to obtain the slope α, then the conversion relationship between the corresponding fractal dimension D rms and the slope α is shown in formula (7).

参见图6,在所述特征匹配装置30进行特征匹配之前,需要通过健康检测训练模型装置50预先训练健康检测模型。所述健康检测训练模型装置50包括数据采集单元501、数据分析单元502、模型函数训练单元503和健康检测模型生成单元504。Referring to FIG. 6 , before the feature matching device 30 performs feature matching, the health detection model needs to be pre-trained by the health detection training model device 50 . The health detection training model device 50 includes a data collection unit 501 , a data analysis unit 502 , a model function training unit 503 and a health detection model generation unit 504 .

在本实施例中,首先所述数据采集单元501采集不同用户不同时间的生理参数以及对应的单导联心电图,然后所述数据分析单元502分析所述数据采集单元501采集的单导联心电图中心电信号pRRx序列的特征数据,所述模型函数训练单元503再通过训练模型算法对所述数据采集单元501采集的生理参数以及所述数据分析单元502对应分析的pRRx序列的特征数据进行机器学习和训练,以生成pRRx序列的特征数据和生理参数对应关系的模型函数,最终所述健康检测模型生成单元504基于所述模型函数训练单元503生成的模型函数和所述数据采集单元501采集的生理参数数据生成健康检测模型。In this embodiment, firstly, the data collection unit 501 collects physiological parameters and corresponding single-lead ECGs of different users at different times, and then the data analysis unit 502 analyzes the center of the single-lead ECGs collected by the data collection unit 501. The characteristic data of the electrical signal pRRx sequence, the model function training unit 503 performs machine learning and analysis on the physiological parameters collected by the data acquisition unit 501 and the characteristic data of the pRRx sequence correspondingly analyzed by the data analysis unit 502 through the training model algorithm Training to generate the model function of the corresponding relationship between the characteristic data of the pRRx sequence and the physiological parameters, and finally the health detection model generation unit 504 is based on the model function generated by the model function training unit 503 and the physiological parameters collected by the data acquisition unit 501 The data generates a health detection model.

其中,所述生理参数包括但不限于:年龄、性别、病史、血糖、体重指数、血压、尿常规、血钾、血红蛋白、血常规、血肌酐、血脂、尿酸、血流动力学监测结果、超声心动图或者颈动脉超声、尿蛋白、朐片、心电图、眼底、吸烟史、心内电生理检查结果、冠状动脉造影结果、疾病类型、阶段、并发症数量及严重程度等。Among them, the physiological parameters include but are not limited to: age, gender, medical history, blood sugar, body mass index, blood pressure, urine routine, blood potassium, hemoglobin, blood routine, blood creatinine, blood lipids, uric acid, hemodynamic monitoring results, ultrasound Cardiogram or carotid ultrasound, urine protein, X-ray film, electrocardiogram, fundus, smoking history, intracardiac electrophysiological examination results, coronary angiography results, disease type, stage, number and severity of complications, etc.

在所述特征分析装置20分析获取到用户的特征数据和健康检测模型后,所述特征匹配装置30进一步将特征分析装置20分析获取的特征数据与所述健康检测训练模型装置50预先训练的健康检测模型进行特征匹配。具体的,所述特征匹配装置30将所述特征分析装置20分析获取的所有特征数据逐项与所述健康检测训练模型装置50预先训练的健康检测模型中的所有特征模板进行相似度匹配,当发现特定特征数据与其中一个特征模板相似度超过预设阈值时,判断两者特征匹配成功,否则判断两者特征匹配失败。After the feature analysis device 20 analyzes and acquires the user's feature data and the health detection model, the feature matching device 30 further combines the feature data acquired by the feature analysis device 20 with the health test model pre-trained by the health detection training model device 50. The detection model performs feature matching. Specifically, the feature matching device 30 performs similarity matching on all the feature data acquired by the feature analysis device 20 and all feature templates in the health detection model pre-trained by the health detection training model device 50 item by item. When it is found that the similarity between the specific feature data and one of the feature templates exceeds the preset threshold, it is judged that the feature matching of the two is successful, otherwise it is judged that the feature matching of the two fails.

在本实施例中,当所述特征匹配装置30将所述特征分析装置20分析获取的特征数据与所述健康检测训练模型装置50预先训练的健康检测模型中特定特征模板匹配时,所述检测数据生成装置40根据所述健康检测模型中心电信号pRRx序列的特征数据和生理参数对应关系的模型函数,可输出所述特定特征模板对应的生理参数数据而生成当前用户身体健康的检测数据,提升了健康筛查的便捷性、舒适性、工作效率和用户体验。In this embodiment, when the feature matching device 30 matches the feature data acquired by the feature analysis device 20 with the specific feature template in the health detection model pre-trained by the health detection training model device 50, the detection The data generation device 40 can output the physiological parameter data corresponding to the specific characteristic template according to the model function of the corresponding relationship between the characteristic data of the electric signal pRRx sequence in the health detection model center and the physiological parameter to generate the detection data of the current user's physical health, and improve It improves the convenience, comfort, work efficiency and user experience of health screening.

在一些实施例中,在所述检测数据生成装置40根据特征匹配的结果生成健康检测数据之后,当生成的检测数据超出预设警戒范围时,还可进一步可通过文字、语音或跳出警报窗口等方式提醒检测数据,参见图7,在另一些实施例中,在上述实施例的基础上,可进一步包括检测报告生成装置70,其包括数据获取单元701、趋势分析单元702和检测报告生成单元703。In some embodiments, after the detection data generating device 40 generates the health detection data according to the result of feature matching, when the generated detection data exceeds the preset warning range, it can further use text, voice or jump out of the alarm window, etc. Ways to remind detection data, see Figure 7, in some other embodiments, on the basis of the above embodiments, a detection report generation device 70 may be further included, which includes a data acquisition unit 701, a trend analysis unit 702 and a detection report generation unit 703 .

在本实施例中,针对同一用户可在多个时间进行单导联心电图检测,所述数据获取单元701获取用户在多个时间的健康监测数据,所述趋势分析单元702分析所述数据获取单元701获取的多个时间的健康监测数据以获取用户的健康趋势数据,所述检测报告生成单元703根据健康监测数据和健康趋势数据获取用户的健康检测报告,可以对用户进行日常监测并做健康筛查,有利于及时发现用户潜在的大病风险,提醒用户及时去医院做相应检查、诊断和及时治疗。In this embodiment, single-lead ECG detection can be performed at multiple times for the same user, the data acquisition unit 701 acquires the health monitoring data of the user at multiple times, and the trend analysis unit 702 analyzes the data acquisition unit 701 obtains the health monitoring data of multiple times to obtain the user’s health trend data, and the detection report generation unit 703 obtains the user’s health detection report according to the health monitoring data and the health trend data, and can perform daily monitoring and health screening for the user. It is helpful to timely discover the potential risk of serious illness of the user, and remind the user to go to the hospital for corresponding examination, diagnosis and timely treatment in time.

图8为本发明再一个实施例中医疗设备的结构示意图。如图所示,本发明再一实施例还提供一种医疗设备200,所述医疗设备200包括上述实施例中的基于单导联心电图的健康数据检测系统100,可以对用户进行日常监测并做健康筛查,有利于及时发现用户潜在的大病风险,提醒用户及时去医院做相应检查、诊断和及时治疗。Fig. 8 is a schematic structural diagram of a medical device in another embodiment of the present invention. As shown in the figure, another embodiment of the present invention also provides a medical device 200, the medical device 200 includes the health data detection system 100 based on the single-lead electrocardiogram in the above embodiment, which can perform daily monitoring on the user and make Health screening is conducive to timely detection of potential serious disease risks of users, and reminds users to go to the hospital for corresponding examination, diagnosis and timely treatment.

应当理解,本发明的各部分可以用硬件、软件、固件或它们的组合来实现。在上述实施方式中,多个步骤或方法可以用存储在存储器中且由合适的指令执行系统执行的软件或固件来实现。例如,如果用硬件来实现,和在另一实施方式中一样,可用本领域公知的下列技术中的任一项或他们的组合来实现:具有用于对数据信号实现逻辑功能的逻辑门电路的离散逻辑电路,具有合适的组合逻辑门电路的专用集成电路,可编程门阵列(PGA),现场可编程门阵列(FPGA)等。It should be understood that various parts of the present invention can be realized by hardware, software, firmware or their combination. In the embodiments described above, various steps or methods may be implemented by software or firmware stored in memory and executed by a suitable instruction execution system. For example, if implemented in hardware, as in another embodiment, it can be implemented by any one or combination of the following techniques known in the art: Discrete logic circuits, ASICs with suitable combinational logic gates, programmable gate arrays (PGAs), field programmable gate arrays (FPGAs), etc.

在本说明书的描述中,参考术语“一个实施例”、“一些实施例”、“示例”、“具体示例”、或“一些示例”等描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本发明的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不一定指的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。In the description of this specification, reference to the terms "one embodiment", "some embodiments", "example", "specific examples", or "some examples" means that specific features described in connection with the embodiment or example, A structure, material or characteristic is included in at least one embodiment or example of the invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.

尽管已经示出和描述了本发明的实施例,本领域的普通技术人员可以理解:在不脱离本发明的原理和宗旨的情况下可以对这些实施例进行多种变化、修改、替换和变型,本发明的范围由权利要求及其等同物限定。Although the embodiments of the present invention have been shown and described, those skilled in the art can understand that various changes, modifications, substitutions and modifications can be made to these embodiments without departing from the principle and spirit of the present invention. The scope of the invention is defined by the claims and their equivalents.

Claims (10)

1. a kind of human health screening method based on single lead electrocardiogram characterized by comprising
Acquire the single lead electrocardiogram of user;
Analyze the characteristic of the single lead electrocardiogram center telecommunications pRRx sequence of acquisition;
The characteristic of the pRRx sequence of analysis and health detection model trained in advance are subjected to characteristic matching;And
The health detection data of user are generated according to the result of characteristic matching.
2. the human health screening method according to claim 1 based on single lead electrocardiogram, which is characterized in that further include training Health detection model, further comprising:
Acquire the physiological parameter and corresponding single lead electrocardiogram of different user different time;
Analyze the characteristic of the single lead electrocardiogram center telecommunications pRRx sequence of acquisition;
Machine is carried out by characteristic of the training pattern algorithm to the physiological parameter of acquisition and the pRRx sequence of correspondence analysis Study and training, to generate the characteristic of pRRx sequence and the pattern function of physiological parameter corresponding relationship;And
The physiological parameter data of pattern function and acquisition based on generation generates health detection model.
3. the health data detection method according to claim 1 or 2 based on single lead electrocardiogram, which is characterized in that After the health detection data for generating user according to the result of characteristic matching, further includes:
User is obtained in the health monitoring data of multiple times;
The health monitoring data of the multiple times obtained are analyzed to obtain the healthy trend data of user;And
It is reported according to the health monitoring data of acquisition and the health detection of healthy trend data acquisition user.
4. the health data detection method according to claim 1 or 2 based on single lead electrocardiogram, which is characterized in that institute The characteristic for stating pRRx sequence is one of linear character and entropy nonlinear characteristic, fractal dimension nonlinear characteristic or group It closes, wherein the linear character is poor for average value, standard deviation, the root mean square of flanking sequence difference, the flanking sequence of pRRx sequence One of standard deviation of value or combination, the fractal dimension nonlinear characteristic are pRRx sequence histogram distributed intelligence entropy, pRRx Sequence power is composed one of histogram distributed intelligence entropy and pRRx sequence power spectrum full frequency band distributed intelligence entropy or is combined, described point Shape dimension nonlinear characteristic calculates resulting fractal dimension for structure function method, correlation function algorithm calculates resulting fractal dimension, Variate-difference method calculates resulting fractal dimension and mean square root method calculates one of resulting fractal dimension or combination.
5. the human health screening method according to claim 1 based on single lead electrocardiogram, which is characterized in that the analysis is adopted The characteristic of the single lead electrocardiogram center telecommunications pRRx sequence of collection, comprising:
The difference for calculating the adjacent pRRx sequence of single lead electrocardiogram center telecommunications number of acquisition is greater than threshold value x milliseconds of quantity and whole The ratio of the quantity of adjacent pRRx sequence;And
PRRx sequence is formed by the corresponding corresponding ratio of each threshold value x that obtains of the different threshold value x of setting value.
6. a kind of human health screening system based on single lead electrocardiogram characterized by comprising
Electrocardiogram acquisition device, for acquiring the single lead electrocardiogram of user;
Feature analyzing apparatus, for analyzing the single lead electrocardiogram center telecommunications pRRx sequence of the electrocardiogram acquisition device acquisition The characteristic of column;
Characteristic matching device, characteristic and the health detection training of the pRRx sequence for analyzing the feature analyzing apparatus The health detection model that model equipment is trained in advance carries out characteristic matching;And
Detection data generating means, for generating the health detection of user according to the matched result of the characteristic matching device characteristic Data.
7. the human health screening system according to claim 6 based on single lead electrocardiogram, which is characterized in that further include health Training pattern device is detected, further comprising:
Data acquisition unit, for acquiring the physiological parameter and corresponding single lead electrocardiogram of different user different time;
Data analysis unit, for analyzing the single lead electrocardiogram center telecommunications pRRx sequence of the data acquisition unit acquisition Characteristic;
Pattern function training unit, physiological parameter for being acquired by training pattern algorithm to the data acquisition unit and The characteristic of the pRRx sequence of the data analysis unit correspondence analysis carries out machine learning and training, to generate pRRx sequence Characteristic and physiological parameter corresponding relationship pattern function;And
Health detection model generation unit, pattern function and the data for being generated based on the pattern function training unit The physiological parameter data of acquisition unit acquisition generates health detection model.
8. the human health screening system according to claim 6 or 7 based on single lead electrocardiogram, which is characterized in that further include Examining report generating means, further comprising:
Data capture unit, for obtaining user in the health monitoring data of multiple times;
Trend analysis unit, for analyzing the health monitoring data for multiple times that the data capture unit obtains to obtain use The healthy trend data at family;And
Examining report generation unit, health monitoring data and the trend analysis for being obtained according to the data capture unit The health detection report of the healthy trend data acquisition user of unit analysis.
9. the health data detection system according to claim 6 or 7 based on single lead electrocardiogram, which is characterized in that institute The characteristic for stating pRRx sequence is one of linear character and entropy nonlinear characteristic, fractal dimension nonlinear characteristic or group It closes, wherein the linear character is poor for average value, standard deviation, the root mean square of flanking sequence difference, the flanking sequence of pRRx sequence One of standard deviation of value or combination, the fractal dimension nonlinear characteristic are pRRx sequence histogram distributed intelligence entropy, pRRx Sequence power is composed one of histogram distributed intelligence entropy and pRRx sequence power spectrum full frequency band distributed intelligence entropy or is combined, described point Shape dimension nonlinear characteristic calculates resulting fractal dimension for structure function method, correlation function algorithm calculates resulting fractal dimension, Variate-difference method calculates resulting fractal dimension and mean square root method calculates one of resulting fractal dimension or combination.
10. a kind of Medical Devices, which is characterized in that the Medical Devices include being based on as claim 6 to 9 is described in any item The human health screening system of single lead electrocardiogram.
CN201910454467.6A 2019-05-28 2019-05-28 Health screening method, system and medical equipment based on single-lead electrocardiogram Pending CN110236522A (en)

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