CN110201548A - A kind of quick peripheral plasma collector and its application method - Google Patents
A kind of quick peripheral plasma collector and its application method Download PDFInfo
- Publication number
- CN110201548A CN110201548A CN201910327922.6A CN201910327922A CN110201548A CN 110201548 A CN110201548 A CN 110201548A CN 201910327922 A CN201910327922 A CN 201910327922A CN 110201548 A CN110201548 A CN 110201548A
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- Prior art keywords
- capillary
- hemofilter
- blood
- air bag
- plasma
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Links
- 230000002093 peripheral effect Effects 0.000 title claims abstract description 13
- 238000000034 method Methods 0.000 title claims abstract description 12
- 210000002381 plasma Anatomy 0.000 claims abstract description 29
- 210000004369 blood Anatomy 0.000 claims abstract description 19
- 239000008280 blood Substances 0.000 claims abstract description 19
- 210000005259 peripheral blood Anatomy 0.000 claims abstract description 16
- 239000011886 peripheral blood Substances 0.000 claims abstract description 16
- 239000012528 membrane Substances 0.000 claims abstract description 13
- 210000003743 erythrocyte Anatomy 0.000 claims abstract description 9
- 210000000481 breast Anatomy 0.000 claims abstract description 4
- 238000001914 filtration Methods 0.000 claims description 5
- 210000005239 tubule Anatomy 0.000 claims description 5
- 238000000926 separation method Methods 0.000 claims description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 238000002615 hemofiltration Methods 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of quick peripheral plasma collector and its application methods, including air bag, the first capillary, hemofilter, the second capillary；The upper end of first capillary is socketed in air bag；The lower end of first capillary connects hemofilter upper end；The lower end of the hemofilter connects the second capillary；The air bag, the first capillary, hemofilter, the second capillary are connected to setting from top to bottom；The bosom of the hemofilter is equipped with blood filter membrane.Red blood cell in peripheral blood is efficiently separated out by the present invention by the blood filter membrane in hemofilter, significantly increases the convenience of micro sampled plasma.
Description
Technical field
The present invention relates to a kind of quick peripheral plasma collector and its application methods.
Background technique
Currently, many quickly detections need to be detected using blood plasma, blood generally is centrifugated using venous blood both at home and abroad
Slurry, and the method needs to acquire more blood, and needs special installation, it is now external to acquire peripheral blood capillary heparin tube
Red blood cell and blood plasma separate precedent not yet, realization of the invention will make it possible micro sampled plasma.
Summary of the invention
In view of the deficiencies of the prior art mentioned above, problems solved by the invention are as follows: providing a kind of take a blood sample by tip can
The collector and its method of quantitatively micro blood plasma are obtained after red blood cell and blood plasma are separated.
To solve the above problems, the technical solution adopted by the present invention is as follows:
A kind of quick peripheral plasma collector, including air bag, the first capillary, hemofilter, the second capillary；Described first mao
The upper end of tubule is socketed in air bag；The lower end of first capillary connects hemofilter upper end；Under the hemofilter
The second capillary of end connection；The air bag, the first capillary, hemofilter, the second capillary are connected to setting from top to bottom；It is described
Hemofilter bosom be equipped with blood filter membrane.
Further, internal diameter of the internal diameter of second capillary less than the first capillary.
A kind of application method of quick peripheral plasma collector, steps are as follows:
S1, the first capillary, hemofilter, the second capillary are successively sealed to connecting；
S2, peripheral blood is taken using the capillary action of the first capillary, acquire and air bag is socketed in first mao after finishing
The upper end of tubule；
S3, air bag is squeezed, so that peripheral blood is flowed from the first capillary to hemofilter, it is red thin after peripheral blood passes through hemofilter
Born of the same parents are isolated by filtration the blood plasma on the blood filtration membrane, separated and penetrate into the second capillary from blood filter membrane, realize peripheral blood
The separation of middle blood plasma and red blood cell.
Further, the internal diameter of second capillary is less than the internal diameter of the first capillary in order to which blood plasma is from the first capillary
Pipe sucks in the second capillary.
Further, second capillary selects different inner diameters and length to realize batcher function according to the demand of capacity
Energy.
Beneficial effects of the present invention
Red blood cell in peripheral blood is efficiently separated out by the present invention by the blood filter membrane in hemofilter, can be taken a blood sample by tip
Obtain quantitative micro blood plasma.
Detailed description of the invention
Fig. 1 is structural schematic diagram of the invention.
Fig. 2 is fractionation structural representation of the invention.
Specific embodiment
The content of present invention is described in further detail with reference to the accompanying drawing.
As illustrated in fig. 1 and 2, a kind of quick peripheral plasma collector, including air bag 1, the first capillary 2, hemofilter 3,
Two capillaries 5.The upper end of first capillary 2 is socketed in air bag 1；The lower end of first capillary 2 connects filter
3 upper end of blood device；The lower end of the hemofilter 3 connects the second capillary 5；The air bag 1, the first capillary 2, hemofilter 3,
Second capillary 5 is connected to setting from top to bottom；The bosom of the hemofilter 3 is equipped with blood filter membrane 4.Second capillary
Internal diameter of the internal diameter of pipe 5 less than the first capillary 2
A kind of application method of quick peripheral plasma collector, steps are as follows:
S1, the first capillary 2, hemofilter 3, the second capillary 5 are successively sealed to connecting.
S2, air bag 1 is socketed in after taking peripheral blood, acquisition to finish using the capillary action of the first capillary 2
The upper end of first capillary 2.
S3, air bag 1 is squeezed, so that peripheral blood is flowed from the first capillary 2 to hemofilter 3, when peripheral blood passes through hemofiltration
Red blood cell is isolated by filtration in blood filter membrane 4 after device 3, and the blood plasma separated penetrates into the second capillary 5 from blood filter membrane,
Realize the separation of blood plasma and red blood cell in peripheral blood.
It is further preferential, the internal diameter of second capillary 5 less than the first capillary 2 internal diameter in order to which blood plasma is from the
One capillary 2 sucks in the second capillary 5.Further preferably, second capillary 5 selects different according to the demand of capacity
Internal diameter and length are to realize batcher function.
Red blood cell in peripheral blood is efficiently separated out by the present invention by the blood filter membrane 4 in hemofilter 3, can pass through end
Tip blood sampling obtains quantitative micro blood plasma.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all in essence of the invention
Within mind and principle, any modification, equivalent replacement, improvement and so on be should all be included in the protection scope of the present invention.
Claims (5)
1. a kind of quick peripheral plasma collector, which is characterized in that including air bag, the first capillary, hemofilter, the second capillary
Pipe；The upper end of first capillary is socketed in air bag；The lower end of first capillary connects hemofilter upper end；Institute
The lower end for the hemofilter stated connects the second capillary；The air bag, the first capillary, hemofilter, the second capillary from upper and
Lower connection setting；The bosom of the hemofilter is equipped with blood filter membrane.
2. quick peripheral plasma collector according to claim 1, which is characterized in that the internal diameter of second capillary
Less than the internal diameter of the first capillary.
3. a kind of application method of quick peripheral plasma collector, which is characterized in that steps are as follows:
S1, the first capillary, hemofilter, the second capillary are successively sealed to connecting；
S2, peripheral blood is taken using the capillary action of the first capillary, acquire and air bag is socketed in first mao after finishing
The upper end of tubule；
S3, air bag is squeezed, so that peripheral blood is flowed from the first capillary to hemofilter, it is red thin after peripheral blood passes through hemofilter
Born of the same parents are isolated by filtration the blood plasma on the blood filtration membrane, separated and penetrate into the second capillary from blood filter membrane, realize peripheral blood
The separation of middle blood plasma and red blood cell.
4. the application method of quick peripheral plasma collector according to claim 3, which is characterized in that described second mao
The internal diameter of tubule less than the first capillary internal diameter in order to which blood plasma is out of first the second capillary of capillary suction.
5. the application method of quick peripheral plasma collector according to claim 3, which is characterized in that described second mao
Tubule selects different inner diameters and length to realize batcher function according to the demand of capacity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910327922.6A CN110201548A (en) | 2019-04-23 | 2019-04-23 | A kind of quick peripheral plasma collector and its application method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910327922.6A CN110201548A (en) | 2019-04-23 | 2019-04-23 | A kind of quick peripheral plasma collector and its application method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN110201548A true CN110201548A (en) | 2019-09-06 |
Family
ID=67786157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910327922.6A Pending CN110201548A (en) | 2019-04-23 | 2019-04-23 | A kind of quick peripheral plasma collector and its application method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110201548A (en) |
Citations (15)
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|---|---|---|---|---|
| US4653511A (en) * | 1984-10-05 | 1987-03-31 | Goch Thomas A | Microsample blood collecting device |
| JP2004344874A (en) * | 2002-11-19 | 2004-12-09 | Sekisui Chem Co Ltd | Separation membrane of plasma or serum and filter apparatus using separation membrane of plasma or serum |
| WO2005094681A1 (en) * | 2004-03-26 | 2005-10-13 | Sarstedt Ag & Co. | Device for collecting capillary blood |
| US20050232813A1 (en) * | 2004-04-16 | 2005-10-20 | Karmali Rashida A | Specimen collecting, processing and analytical assembly |
| JP2007003484A (en) * | 2005-06-27 | 2007-01-11 | Sekisui Chem Co Ltd | Specimen sampling container |
| CN201073303Y (en) * | 2007-02-11 | 2008-06-18 | 陈士连 | Disposable trace quantity blood samplingd evice |
| CN103499525A (en) * | 2013-09-03 | 2014-01-08 | 冯晓均 | Blood sample biochemical quantitative detection device |
| US20140154796A1 (en) * | 2012-12-03 | 2014-06-05 | Stanislav L. Karsten | Sampling Device and Method for Collection and Preservation of Live Cells from Tissues and Cell Cultures |
| CN205175737U (en) * | 2015-10-27 | 2016-04-20 | 光景生物科技(苏州)有限公司 | Blood sampling external member |
| CN205941073U (en) * | 2016-04-29 | 2017-02-08 | 广州天宝颂原生物科技开发有限公司 | Disposable ration blood sampling straw |
| TWI569861B (en) * | 2016-04-22 | 2017-02-11 | 國立高雄大學 | Blood adsorption separation material, blood filtration device and operation method thereof |
| CN206656887U (en) * | 2017-04-20 | 2017-11-21 | 遵义医学院附属医院 | On special-purpose taking blood taking bag in heparin tube blood constituent cross matching Dispette |
| US20180136194A1 (en) * | 2016-11-16 | 2018-05-17 | Quidel Corporation | Device for whole blood separation |
| CN208505741U (en) * | 2018-06-19 | 2019-02-15 | 江苏科华医疗器械科技有限公司 | A kind of novel all-in-one sample diluting device |
| CN209934477U (en) * | 2019-04-23 | 2020-01-14 | 江苏科华医疗器械科技有限公司 | Quick tip plasma collector |
-
2019
- 2019-04-23 CN CN201910327922.6A patent/CN110201548A/en active Pending
Patent Citations (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4653511A (en) * | 1984-10-05 | 1987-03-31 | Goch Thomas A | Microsample blood collecting device |
| JP2004344874A (en) * | 2002-11-19 | 2004-12-09 | Sekisui Chem Co Ltd | Separation membrane of plasma or serum and filter apparatus using separation membrane of plasma or serum |
| WO2005094681A1 (en) * | 2004-03-26 | 2005-10-13 | Sarstedt Ag & Co. | Device for collecting capillary blood |
| US20050232813A1 (en) * | 2004-04-16 | 2005-10-20 | Karmali Rashida A | Specimen collecting, processing and analytical assembly |
| CN1969184A (en) * | 2004-04-16 | 2007-05-23 | 拉希达·A·卡马利 | Sample Collection, Processing and Analysis Components |
| JP2007003484A (en) * | 2005-06-27 | 2007-01-11 | Sekisui Chem Co Ltd | Specimen sampling container |
| CN201073303Y (en) * | 2007-02-11 | 2008-06-18 | 陈士连 | Disposable trace quantity blood samplingd evice |
| US20140154796A1 (en) * | 2012-12-03 | 2014-06-05 | Stanislav L. Karsten | Sampling Device and Method for Collection and Preservation of Live Cells from Tissues and Cell Cultures |
| CN103499525A (en) * | 2013-09-03 | 2014-01-08 | 冯晓均 | Blood sample biochemical quantitative detection device |
| CN205175737U (en) * | 2015-10-27 | 2016-04-20 | 光景生物科技(苏州)有限公司 | Blood sampling external member |
| TWI569861B (en) * | 2016-04-22 | 2017-02-11 | 國立高雄大學 | Blood adsorption separation material, blood filtration device and operation method thereof |
| CN205941073U (en) * | 2016-04-29 | 2017-02-08 | 广州天宝颂原生物科技开发有限公司 | Disposable ration blood sampling straw |
| US20180136194A1 (en) * | 2016-11-16 | 2018-05-17 | Quidel Corporation | Device for whole blood separation |
| CN206656887U (en) * | 2017-04-20 | 2017-11-21 | 遵义医学院附属医院 | On special-purpose taking blood taking bag in heparin tube blood constituent cross matching Dispette |
| CN208505741U (en) * | 2018-06-19 | 2019-02-15 | 江苏科华医疗器械科技有限公司 | A kind of novel all-in-one sample diluting device |
| CN209934477U (en) * | 2019-04-23 | 2020-01-14 | 江苏科华医疗器械科技有限公司 | Quick tip plasma collector |
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| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190906 |