CN110141704B

CN110141704B - ECMO closed prefilling device

Info

Publication number: CN110141704B
Application number: CN201910361604.1A
Authority: CN
Inventors: 鲁玉凤; 郭林; 叶婷; 董东伟; 王凤珍; 刘子由; 陈洪; 胡硕
Original assignee: First Affiliated Hospital of Gannan Medical University
Current assignee: First Affiliated Hospital of Gannan Medical University
Priority date: 2019-04-30
Filing date: 2019-04-30
Publication date: 2024-06-14
Anticipated expiration: 2039-04-30
Also published as: CN110141704A

Abstract

The invention relates to the field of medical equipment and discloses an ECMO closed type pre-flushing device which comprises an ECMO device and a precise transfusion suite communicated with the ECMO device, wherein the ECMO device comprises an ECMO machine, a centrifugal pump, a membrane lung, a drainage tube from an outlet end of the membrane lung to an inlet end of the centrifugal pump, a drainage tube from an outlet end of the centrifugal pump to an inlet end of the membrane lung and two interfaces on the drainage tube from an outlet end of the membrane lung to an inlet end of the centrifugal pump, the precise transfusion suite comprises a reflux bag and a pre-flushing bag, the pre-flushing bag and the reflux bag are communicated through a channel, the channel is provided with a filter head and a one-way check valve, and ECMO pre-flushing pipes for connecting the two interfaces are respectively arranged at the lower parts of the pre-flushing bag and the reflux bag. The invention breaks the bubble of the pre-flushing liquid in the pipe through the filter head, the pre-flushing liquid circulates and pre-flushes after passing through the one-way check valve, the pipeline pre-flushing of the ECMO device is realized, the air and the air bubbles in the pipeline are replaced, the time is saved, the pollution is reduced, the pre-flushing is thorough, the effective implementation of the ECMO is ensured, and the time is strived for rescuing patients.

Description

ECMO closed prefilling device

Technical Field

The invention relates to the field of medical equipment, in particular to an ECMO closed type pre-charging device.

Background

External membrane oxygenation (ECMO) is a technique for rescuing patients with severe heart and lung failure, representing a national, regional, hospital critical illness rescue level, and it is even currently believed that ECMO technology redefines the life and death boundaries. ECMO is an extracorporeal circulation technology which leaves a heart operating room, and the principle is that venous blood in a body is led out of the body, and is injected into an artery or a vein system of a patient after being subjected to artificial cardiopulmonary bypass oxygenation by special materials, so that partial cardiopulmonary substitution effect is achieved, and oxygenation blood supply of organ tissues of a human body is maintained.

The basic structure of ECMO comprises intravascular cannula, connecting tube, centrifugal pump (artificial heart), oxygenator (artificial lung), oxygen supply tube, and monitoring system. The disposable part is often formed into a bag in clinic, and the non-disposable part is bound and stored and is designed to be movable, so that the emergency capability is improved.

The function of the membrane lung is to oxidize non-oxygenated blood to oxygenated blood, also known as artificial lung. The ECMO oxygenator has two types, namely a silica gel film type and a hollow fiber type. The silica gel film type membrane has good lung compatibility, little plasma leakage and little damage to blood components, and is suitable for long-time assistance. For example, support of respiratory failure due to cardiopulmonary function waiting for transplantation and infection. The disadvantage is that it is difficult to exhaust and expensive. The hollow fiber membrane lung is easy to exhaust, plasma leakage is visible for 2-3 days, and the damage of blood components is relatively large, but the hollow fiber membrane lung is still the first-aid kit due to simple installation. If desired, the appropriate oxygenator may be replaced within one to two days after the condition is stabilized.

The function of the centrifugal pump is to create a motive force that drives the blood flow to one side of the conduit, resembling the function of the heart. There are mainly two types of centrifugal pumps in clinic: roller pump, centrifugal pump. Because the roller pump is not easy to move and difficult to manage, the centrifugal pump is preferred to be used as the centrifugal pump in the first-aid profession. The device has the advantages of convenient installation and movement, convenient management and small blood damage; the suction effect is realized within a reasonable negative pressure range, so that the problem of low flow caused by some reasons can be solved; the new generation of centrifugal pump is easy to control for low flow rate of children.

Along with the progress of technology, ECMO is increasingly used in critical diseases, but before the ECMO is used, the pipeline needs to be pre-filled, if the pre-filling and the air discharging are not thorough, air embolism can be generated, membrane lung coagulation is caused, and the life of a patient is threatened. Meanwhile, the primary pre-filling is not thorough, the time for secondary pre-filling is increased, the cost of patients is increased, and the like, so that the timely and effective application of ECMO is affected.

Disclosure of Invention

The invention aims to solve the problems, and provides an ECMO closed type pre-filling device, which can destroy pre-flushing liquid bubbles in a pipe through a filter head, can circularly pre-flush the pre-flushing liquid after the pre-flushing liquid passes through the filter head and a one-way check valve, and can realize pre-flushing of a pipeline of the ECMO device only by a small amount of pre-flushing liquid, and replace air and bubbles in the pipeline.

In order to achieve the above purpose, the ECMO closed type pre-charging device of the present invention is communicated with an ECMO device, where the ECMO device includes an ECMO machine, a centrifugal pump, a membrane lung, a drainage tube from an outlet end of the membrane lung to an inlet end of the centrifugal pump, a drainage tube from an outlet end of the centrifugal pump to an inlet end of the membrane lung, and a first interface and a second interface on the drainage tube from the outlet end of the membrane lung to the inlet end of the centrifugal pump;

A precision infusion set connected with the ECMO device, wherein the precision infusion set comprises a reflux bag and a pre-flushing bag;

the pre-flushing bag is communicated with the reflux bag through a channel, the channel is provided with a filter head and a one-way check valve, the lower part of the pre-flushing bag is provided with an ECMO pre-flushing pipe I of a first interface on a drainage tube which is connected with the outlet end of the membrane lung to the inlet end of the centrifugal pump, and the lower part of the reflux bag is provided with an ECMO pre-flushing pipe II of a second interface on the drainage tube which is connected with the outlet end of the membrane lung to the inlet end of the centrifugal pump;

the filter head is used for destroying bubbles in the pre-flushing liquid;

a jaw portion including a first vascular clamp, a second vascular clamp, a third vascular clamp, and a fourth vascular clamp;

The first vascular clamp is arranged on the ECMO drainage tube between the first interface and the second interface, and can prevent pre-flushing liquid flowing out of the outlet end of the membrane lung from returning to the inlet end of the centrifugal pump after being clamped;

the second vascular clamp is arranged on the drainage tube from the outlet end of the centrifugal pump to the inlet end of the membranous lung and is used for clamping a pipeline at the position when the ECMO machine is started or stopped;

The third vascular clamp is arranged on the second ECMO pre-flushing pipe at the lower part of the reflux bag;

the fourth vascular clamp is arranged on the ECMO pre-flushing pipe I at the lower part of the pre-flushing bag, and the third vascular clamp and the fourth vascular clamp can close/open the flow of pre-flushing liquid.

Preferably, the filter head is positioned on a channel which is communicated with the reflux bag and the pre-flushing bag and is fixedly connected with the one-way check valve.

Preferably, the filter head is a hollow structure composed of an outlet end, an inlet end and side walls extending therebetween, and the side walls of the filter head are provided with a plurality of filter holes penetrating along the side wall direction.

Preferably, the diameter of the filtering holes is 0.3-0.6 mm, and the length of the filtering holes is 5-8 mm.

Preferably, the filter head is of a boss type hollow structure, the left end of the filter head is an inlet end connected with the reflux bag, the right end of the filter head is an outlet end connected with the one-way check valve, and the opening diameter of the inlet end of the left end of the filter head is larger than that of the outlet end of the right end.

Preferably, the one-way check valve is a one-way valve body, the pre-flushing liquid entering the filter head can only enter the pre-flushing bag through the one-way check valve, and the pre-flushing liquid of the pre-flushing bag cannot directly enter the reflux bag through the one-way check valve.

Preferably, the first interface and the second interface are provided with internal threads, and one end of the ECMO pre-flushing pipe II at the lower part of the reflux bag and one end of the ECMO pre-flushing pipe I at the lower part of the pre-flushing bag are provided with external threads;

Preferably, the external thread of the first ECMO pre-flushing pipe at the lower part of the pre-flushing bag can be connected with the internal thread of the first interface, and the external thread of the second ECMO pre-flushing pipe at the lower part of the reflux bag can be connected with the internal thread of the second interface.

Preferably, the other end of the second ECMO pre-flushing pipe at the lower part of the reflux bag and the other end of the first ECMO pre-flushing pipe at the lower part of the pre-flushing bag are provided with puncture needles for connecting the pre-flushing bag and the reflux bag.

Preferably, the height of the channel, the filter head and the one-way check valve which are communicated with the pre-flushing bag and the reflux bag are positioned on the same horizontal plane and at 1/3-1/4 of the height of the pre-flushing bag.

Preferably, the bottom surfaces of the pre-flush bag and the return bag are the same size, and the volume of the return bag is not more than half of the volume of the pre-flush bag.

The beneficial effects of the invention are as follows: when the height of the pre-flushing liquid in the reflux bag exceeds the height of the filter head, the pre-flushing liquid in the reflux bag enters the pre-flushing bag through the filter head and the one-way check valve, and bubbles in the pre-flushing liquid are intercepted and destroyed through the filter head, so that bubbles are not easy to enter the ECMO pipeline, and the pre-flushing liquid can circulate in the pipeline. The whole pre-flushing is carried out in a closed environment, so that the tube drawing and intubation during the replacement of the pre-flushing bag in the traditional pre-flushing are avoided, the whole operation process is sterile, compared with the traditional method, the pre-flushing is more thorough, the time can be saved, the pollution is reduced, the effective implementation of ECMO can be ensured, the working efficiency is improved, the time is struggled for rescuing patients, and the cost is saved.

Drawings

FIG. 1 is a schematic diagram of an ECMO closed type pre-punching device according to a preferred embodiment of the present invention;

FIG. 2 is a cross-sectional view of a filter head of the present invention;

FIG. 3 is a cross-sectional view of a precision infusion set in accordance with a preferred embodiment of the invention;

Description of the reference numerals

1-Centrifugal pump, 2-membrane lung, 3-drainage tube, 31-interface one, 32-interface two, 4-drainage tube, 5-pre-flush bag, 51-ECMO pre-flush tube one, 6-reflux bag, 61-ECMO pre-flush tube two, 7-channel, 71-filter head, 711-outlet end, 712-inlet end, 713-sidewall 713, 714-filter hole, 72-one-way check valve, 81-first vascular clamp, 82-second vascular clamp, 83-third vascular clamp, 81-fourth vascular clamp.

Detailed Description

The invention will be described in detail below with reference to the drawings and the detailed description. It should be understood that the detailed description and specific examples, while indicating and illustrating the invention, are not intended to limit the invention.

Referring to fig. 1,2 and 3, the present invention provides an ECMO sealed priming device for priming the ECMO device.

The ECMO improved closed type pre-charging device is communicated with an ECMO device, wherein the ECMO device comprises an ECMO machine, a centrifugal pump 1, a membrane lung 2, a drainage tube 3 from the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1, a drainage tube 4 from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2, and a first interface 31 and a second interface 32 on the drainage tube 3 from the outlet end of the membrane lung 2 to the inlet end of the centrifugal pump 1 in the prior art; ;

The ECMO closed type pre-filling device further comprises a precise transfusion suite connected with the ECMO device, wherein the precise transfusion suite comprises a reflux bag 6 and a pre-flushing bag 5;

The pre-flushing bag 5 and the reflux bag 6 are communicated through a channel 7, the channel 7 is provided with a filter head 71 and a one-way check valve 72, the lower part of the pre-flushing bag 5 is provided with an ECMO pre-flushing pipe I51 which is connected with the outlet end of the membrane lung 2 to a first port 31 on the drainage tube 3 at the inlet end of the centrifugal pump 1, the lower part of the reflux bag 6 is provided with an ECMO pre-flushing pipe II 61 which is connected with the outlet end of the membrane lung 2 to a second port 32 on the drainage tube 3 at the inlet end of the centrifugal pump 1, and the pre-flushing bag 6 is used for providing pre-flushing liquid;

the filter head 71 is used for destroying bubbles in the pre-flushing liquid, the filter head 71 is provided with a filter hole 714, the filter hole 714 is communicated with the inside of the filter head 71, the reflux bag 6 and the one-way check valve 72, and when the pre-flushing liquid passes through the filter hole 714 of the filter head 71, the bubbles in the pre-flushing liquid can be destroyed.

The ECMO sealed priming device of the present invention is further provided with a jaw comprising a first vascular clamp 81, a second vascular clamp 82, a third vascular clamp 83 and a fourth vascular clamp 84;

The first vascular clamp 81 is arranged on the ECMO drainage tube 3 between the first port 31 and the second port 32, and prevents the pre-flushing liquid flowing out of the outlet end of the membrane lung 2 from returning to the inlet end of the centrifugal pump 1 after the first vascular clamp 81 is clamped.

The second vascular clamp 82 is arranged on the drainage tube 4 from the outlet end of the centrifugal pump 1 to the inlet end of the membrane lung 2, and the second vascular clamp 82 clamps the pipeline of the drainage tube 4 when the ECMO machine is started up/stopped;

A third vascular clamp 83 is arranged on the second ECMO pre-flushing pipe 61 at the lower part of the reflux bag 6, a fourth vascular clamp 84 is arranged on the first ECMO pre-flushing pipe 51 at the lower part of the pre-flushing bag 5, and the third vascular clamp 83 and the fourth vascular clamp 84 can close/open the flow of pre-flushing liquid.

When the invention is used for pre-flushing an ECMO pipeline, the pre-flushing liquid in the pre-flushing bag 5 is returned to the reflux bag 6 through the centrifugal pump 1 and the membrane lung 2 by the operation of the centrifugal pump 1, and when the height of the pre-flushing liquid in the reflux bag 6 exceeds the height of the filter head 71, the pre-flushing liquid enters the pre-flushing bag 5 through the filter head 71 and the one-way check valve 72, so that the circulating pre-flushing of the ECMO device is realized.

The first vessel clamp 81 is clamped such that the return bag 6, the pre-flush bag 5 and the channel 8 connecting the pre-flush bag 5 and the return bag 6 are a circulating pre-flush bypass replacing the length of tubing.

The filter head 71 is a hollow structure composed of an outlet end 711, an inlet end 712 and a side wall 713 extending therebetween, and the side wall 713 of the filter head 71 is provided with a plurality of filter holes 714 penetrating in the side wall direction, and the filter holes 714 communicate the inside of the filter head 71 with the reflux bag 6 and the one-way check valve 72.

The filter head 71 is a boss hollow structure with a large end and a small end, the large end is a pre-flushing liquid inlet end 712, and the small end is a pre-flushing liquid outlet end 711; the one-way check valve 72 is a one-way valve body, and the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way check valve 72, and the pre-flushing liquid in the pre-flushing bag 5 cannot directly enter the reflux bag 6 through the one-way check valve 72.

In a preferred embodiment of the present invention, the filter holes 714 have a diameter of 0.3 to 0.6mm and the filter holes 714 have a length of 5 to 8mm, and are capable of filtering bubbles in the pre-flush liquid so that the bubbles are ruptured after passing through the filter head 71.

Referring to fig. 3, in a preferred embodiment of the present invention, when the passage 7, the filter head 71 and the one-way check valve 72 communicating the pre-flushing bag 5 and the return bag 6 are located on the same horizontal level and at 1/4 of the height of the pre-flushing bag 5, and the pre-flushing liquid volume in the pre-flushing bag 5 is lowered by a height not smaller than the height of the filter head 71, the pre-flushing liquid height in the return bag 6 has exceeded the height of the filter head 71 and/or the pre-flushing liquid has filled the return bag 6, the circulating pre-flushing of the pre-flushing liquid is achieved.

The filter head 71 is of a boss type hollow structure, the left end of the filter head 71 is provided with an inlet end 712 which is connected with the reflux bag 6, the right end is provided with an outlet end 711 which is connected with the one-way check valve 72, the opening diameter of the inlet end 712 at the left end of the filter head 71 is larger than that of the outlet end 711 at the right end, and the design can enable bubbles to enter the filter head 71 more quickly and destroy the bubbles after passing through the filter holes 714.

The one-way check valve 72 is a one-way valve body, and the pre-flushing liquid entering the filter head 71 can only enter the pre-flushing bag 5 through the one-way check valve 72, and the pre-flushing liquid of the pre-flushing bag 5 cannot directly enter the reflux bag 6 through the one-way check valve 72.

In the prior ECMO device, the first interface 31 and the second interface 32 are provided with internal threads, and in a preferred embodiment of the invention, the external threads are arranged at the outlets of the second ECMO pre-flushing pipe 61 at the lower part of the reflux bag 6 and the first ECMO pre-flushing pipe 51 at the lower part of the pre-flushing bag 5, the external threads of the first ECMO pre-flushing pipe 51 at the lower part of the pre-flushing bag 5 are connected with the internal threads of the first interface 31, and the external threads of the second ECMO pre-flushing pipe 61 at the lower part of the reflux bag 6 are connected with the internal threads of the second interface 32, so that the quick communication between the precise transfusion suite and the ECMO pipeline is realized.

In a preferred embodiment of the invention, a plastic steel needle is arranged at the other end of the second ECMO pre-flushing pipe 61 at the lower part of the reflux bag 6 and the other end of the first ECMO pre-flushing pipe 51 at the lower part of the pre-flushing bag 5, so that the plastic steel needle can be quickly and directly inserted into the pre-flushing bag 5 and the reflux bag 6 to realize quick connection of the first ECMO pre-flushing pipe 51 and the pre-flushing bag 5, and quick connection of the second ECMO pre-flushing pipe 61 and the reflux bag 6.

In a preferred embodiment of the present invention, the reflux drum 6 and the pre-punching drum 5 may be manufactured in a bottle shape or a bag shape, and the bottom surface of the reflux drum 6 is the same size as the pre-punching drum 5; and/or the volume of the reflux bag 6 does not exceed half of the volume of the pre-flushing bag 5, the volume relation between the pre-flushing bag 5 and the reflux bag 6 satisfies that the height of the drop of the pre-flushing liquid in the pre-flushing bag 5 is not less than the height of the filter head 71, and the pre-flushing liquid height in the reflux bag 6 exceeds the height of the filter head 71, so that the pre-flushing circulation pre-flushing can be ensured.

In a preferred embodiment of the present invention, the use of the ECMO closed type pre-punching apparatus for pre-punching includes the steps of:

s1, preparing an ECMO pre-punched object and an ECMO machine, and ensuring that the ECMO machine is in a complete state;

s2, preparing ECMO pre-flushing liquid, and then adding the pre-flushing liquid into a pre-flushing bag 5 of the precise transfusion suite;

S3, connecting all parts of the ECMO device and the pre-punching device;

s4, firstly removing air in a pipeline of the drainage tube 3 at the inlet end of the centrifugal pump 1 by using the gravity principle, and then removing air in a pump head of the centrifugal pump 1;

S5, pre-flushing is carried out by utilizing the centrifugal pump 1;

and S6, after the pre-flushing is finished, the internal tube of the patient is finished, and the ECMO sleeve is opened to be connected with the internal tube of the patient.

Step S1, preparing an ECMO machine, a vascular clamp, a coupling agent, 700-800ml of ringer' S solution, a precise transfusion kit and an ECMO kit; the instrument validation includes connecting the ECMO power source, connecting the oxygen source and the gas source, and checking that the instrument is in a good standby state.

Step S2 comprises the steps of preparing 700-800ml of ringer' S solution into a pre-flushing bag 5 of a precise transfusion set, inserting a puncture needle of an ECMO pre-flushing pipe I51 into the pre-flushing bag 5, inserting a puncture needle of an ECMO pre-flushing pipe II 61 into a reflux bag 6, and keeping the ECMO pre-flushing pipe I51 and the ECMO pre-flushing pipe II 61 to be aseptically hung on an ECMO transfusion frame.

Step S3, connecting an ECMO device and a pre-flushing device, firstly opening an ECMO bag, connecting a drainage tube 3 with the inlet end of a centrifugal pump 1, fixing the drainage tube by using a self-locking ribbon, connecting a first interface 31 with a first ECMO pre-flushing tube 51 in a threaded manner, arranging a membrane lung 2 on an ECMO fixing frame, switching on an oxygen source and an air source, simultaneously starting a variable-temperature water tank, adding sterilizing injection water and not exceeding a water line, setting the temperature to be 35-37 ℃, connecting a pressure extension tube at two ends of an ECMO machine oxygenator, connecting the outlet end of the membrane lung 2 with the other end of the drainage tube 3, and connecting a second interface 32 with a second ECMO pre-flushing tube 61 in a threaded manner; after connection, the smooth pipeline is confirmed, the devices are firmly connected, and then the first vascular clamp 81 is used for clamping the ECMO drainage tube 3 between the first port 31 and the second port 32, and the clamping position is close to the inlet end of the centrifugal pump 1.

S4, opening a third vascular clamp 83 and a fourth vascular clamp 84, and enabling pre-flushing liquid to flow into a drainage tube 3 pipeline at the inlet end of the centrifugal pump 1 due to self gravity, and discharging air in an ECMO pre-flushing tube I51 at the front end drainage tube 3 of the centrifugal pump 1 and the bottom of the pre-flushing bag 5 by matching with the vascular clamp;

s42, reversely exhausting by using the vascular clamps again, exhausting air in the centrifugal pump 1, and enabling the second vascular clamps 82 to clamp a drainage tube 4 pipeline between the centrifugal pump 1 and the membrane lung 2 before the pre-flushing liquid reaches the membrane lung 2;

in the first pre-flushing step S41, the drainage tube 3 is connected with the centrifugal pump 1, the first port 31 is in threaded connection with the first ECMO pre-flushing tube 51, and then the fourth vascular clamp 84 is opened, so that air in the drainage tube 3 at the front end of the centrifugal pump 1 and the first ECMO pre-flushing tube 51 at the bottom of the pre-flushing bag 5 is discharged faster under the action of gravity, and when the centrifugal pump 1 is filled with pre-flushing liquid, the outlet end of the centrifugal pump 1 is communicated with the inlet end of the membrane lung 2 through the drainage tube 4, so that the pre-flushing time can be shortened.

S5, coating a coupling agent on the end of the centrifugal pump 1, and then loading the coupling agent into a driving device of the centrifugal pump 1 of the ECMO machine;

s52, instrument zeroing: starting the instrument for self-checking, wherein the instrument main switch is always kept in an ON state, and four 0 s appear ON a screen after a return-to-0 key is pressed for a long time, namely, the return-to-zero is successful;

S53, turning the centrifugal pump 1 to 1500, opening a second vascular clamp 82 at the outlet of the pump head of the centrifugal pump 1, turning the centrifugal pump 1 to 2500, and paying attention to the liquid levels in the reflux bag 6 and the pre-flushing bag 5; checking whether air bubbles remain in each joint in the pre-filling process, fastening each joint, and simultaneously removing air from the pressure extension pipes at two ends, the front and rear films of the films and the joints above the films;

S54, when the height of the pre-flushing liquid in the reflux bag 6 and the pre-flushing bag 5 is higher than that of the filter head 71, the ECMO starts self-circulation to remove residual bubbles in the pipeline, and no bubbles in the pipeline are confirmed again.

The step S6 comprises the following steps: s61, rotating the centrifugal pump 1 to 1500, clamping a drainage tube 4 pipeline at the outlet end of the centrifugal pump 1 by using a second vascular clamp 82, immediately rotating to 0, removing an ECMO pre-flushing pipe II 61 and an ECMO pre-flushing pipe I51, connecting an interface I31 and an interface II 32 by using a heparin cap, rotating to 1500, simultaneously loosening the first vascular clamp 81 and the second vascular clamp 82, and starting self-circulation of the instrument;

S62, placing the arterial cannula and the venous cannula, stopping the ECMO machine, opening the sleeve package, delivering the pipeline to a bench doctor in a sterile environment, straightening the whole circulating pipeline, and fixing the pipeline in a proper position.

In the pre-flushing process, air in the ECMO pipeline is replaced by the pre-flushing liquid in the precise transfusion suite, and bubbles in the pre-flushing liquid are destroyed by interception of the filter head 71, so that the circularly flowing pre-flushing liquid does not contain air, and the air in the ECMO pipeline can be discharged after repeated circularly pre-flushing; after the pre-flushing liquid in the pre-flushing bag 5 is pumped into the reflux bag 6, the reflux liquid flows back into the pre-flushing bag 5 through the channel 7, and the whole pre-flushing liquid can circularly flow.

The whole pre-flushing is carried out in a closed environment, so that the problem that the pre-flushing is not thorough due to tube drawing and intubation in the traditional pre-flushing process is avoided, the whole operation process is sterile, compared with the traditional method, the pre-flushing is more thorough, the time can be saved, the pollution can be reduced, the occurrence probability of complications such as membrane lung coagulation and air embolism can be reduced, the effective implementation of ECMO can be ensured, the working efficiency can be improved, the time can be saved for rescuing patients, and the cost can be saved.

The basic structure, the operation method and the advantages of the present invention are explained above for the preferred embodiment of the present invention, but the present invention is not limited thereto, and the technical solution of the present invention may be variously modified, including the combination of the respective technical features in any other suitable manner, within the scope of the technical concept of the present invention, and the simple modification and combination should also be regarded as the disclosure of the present invention, and all fall within the scope of the present invention.

Claims

1. An ECMO closed priming device comprising:

The ECMO device comprises an ECMO machine, a centrifugal pump (1), a membrane lung (2), a drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1), a drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2), and a first interface (31) and a second interface (32) on the drainage tube (3) from the outlet end of the membrane lung (2) to the inlet end of the centrifugal pump (1);

A precision transfusion set connected with the ECMO device, wherein the precision transfusion set comprises a reflux bag (6) and a pre-flushing bag (5);

The pre-flushing bag (5) is communicated with the reflux bag (6) through a channel (7), the channel (7) is provided with a filter head (71) and a one-way check valve (72), the lower part of the pre-flushing bag (5) is provided with an ECMO pre-flushing pipe I (51) for connecting the outlet end of the membrane lung (2) to a first interface (31) on a drainage tube (3) at the inlet end of the centrifugal pump (1), and the lower part of the reflux bag (6) is provided with a second ECMO pre-flushing pipe I (61) for connecting the outlet end of the membrane lung (2) to a second interface (32) on the drainage tube (3) at the inlet end of the centrifugal pump (1);

The filter head (71) is used for destroying bubbles in the pre-flushing liquid; the filter head (71) is of a boss type hollow structure, the left end of the filter head (71) is provided with an inlet end (712) which is connected with the reflux bag (6), the right end of the filter head is provided with an outlet end (711) which is connected with the one-way check valve (72), and the opening diameter of the inlet end (712) at the left end of the filter head (71) is larger than that of the outlet end (711) at the right end;

The one-way check valve (72) is a one-way valve body, the pre-flushing liquid entering the filter head (71) can only enter the pre-flushing bag (5) through the one-way check valve (72), and the pre-flushing liquid of the pre-flushing bag (5) cannot directly enter the reflux bag (6) through the one-way check valve (72);

A jaw portion including a first vascular clamp (81), a second vascular clamp (82), a third vascular clamp (83), and a fourth vascular clamp (84);

The first vascular clamp (81) is arranged on the ECMO drainage tube (3) between the first interface (31) and the second interface (32), and after the first vascular clamp (81) is clamped, the pre-flushing liquid flowing out of the outlet end of the membrane lung (2) can be prevented from returning to the inlet end of the centrifugal pump (1);

The second vascular clamp (82) is arranged on the drainage tube (4) from the outlet end of the centrifugal pump (1) to the inlet end of the membrane lung (2) and is used for clamping a pipeline at the position when the ECMO machine is started up/stopped;

The third vascular clamp (83) is arranged on the ECMO pre-flushing pipe II (61) at the lower part of the reflux bag (6);

The fourth vascular clamp (84) is arranged on the ECMO pre-flushing pipe I (51) at the lower part of the pre-flushing bag (5), and the third vascular clamp (83) and the fourth vascular clamp (84) can close/open the flow of pre-flushing liquid.

2. ECMO closed priming device according to claim 1, characterized in that the filter head (71) is located on a channel (7) communicating a return bag (6) and a pre-flushing bag (5) and is fixedly connected with the one-way check valve (72).

3. ECMO closed priming device according to claim 2, characterized in that the filter head (71) is a hollow structure consisting of an outlet end (711), an inlet end (712) and side walls (713) extending therebetween, the side walls (713) of the filter head (71) being provided with a plurality of filter holes (714) penetrating in the direction of the side walls.

4. An ECMO closed priming device as claimed in claim 3, wherein the diameter of the filter holes (714) is 0.3-0.6 mm, and the length of the filter holes (714) is 5-8 mm.

5. The ECMO closed type pre-filling apparatus according to any one of claims 1 to 4, wherein the first port (31) and the second port (32) are provided with internal threads, and one end of the second ECMO pre-flushing pipe (61) at the lower part of the reflux bag (6) and one end of the first ECMO pre-flushing pipe (51) at the lower part of the pre-flushing bag (5) are provided with external threads;

the external thread of the ECMO pre-flushing pipe I (51) at the lower part of the pre-flushing bag (5) can be connected with the internal thread of the connector I (31), and the external thread of the ECMO pre-flushing pipe II (61) at the lower part of the reflux bag (6) can be connected with the internal thread of the connector II (32).

6. ECMO closed type pre-filling apparatus according to any one of claims 1 to 4, characterized in that the other end of the ECMO pre-flushing pipe two (61) at the lower part of the reflux bag (6) and the other end of the ECMO pre-flushing pipe one (51) at the lower part of the pre-flushing bag (5) are provided with puncture needles for connecting the pre-flushing bag (5) and the reflux bag (6).

7. ECMO closed priming device according to any one of claims 1 to 4, characterized in that the channel (7) connecting the pre-flush bag (5) and the return bag (6), the filter head (71) and the one-way check valve (72) are at the same level and at the level of the pre-flush bag (5)Where it is located.

8. ECMO closed priming device according to claim 6, characterized in that the bottom surfaces of the priming bag (5) and the return bag (6) are of the same size and the volume of the return bag (6) does not exceed half the volume of the priming bag (5).