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CN110095887A - Contact lens cleaning and sterilizing care instrument based on physical method - Google Patents

Contact lens cleaning and sterilizing care instrument based on physical method Download PDF

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Publication number
CN110095887A
CN110095887A CN201910441974.6A CN201910441974A CN110095887A CN 110095887 A CN110095887 A CN 110095887A CN 201910441974 A CN201910441974 A CN 201910441974A CN 110095887 A CN110095887 A CN 110095887A
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China
Prior art keywords
contact lens
cleaning
ultraviolet lamp
physical method
care instrument
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CN201910441974.6A
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孙雯
蒋宇强
芮冰如
俞晨
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HANGZHOU SHIHENG PHOTOELECTRIC CO Ltd
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HANGZHOU SHIHENG PHOTOELECTRIC CO Ltd
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Priority to CN201910441974.6A priority Critical patent/CN110095887A/en
Publication of CN110095887A publication Critical patent/CN110095887A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/02Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using physical phenomena, e.g. electricity, ultrasonics or ultrafiltration
    • A61L12/06Radiation, e.g. ultraviolet or microwaves
    • A61L12/063Ultraviolet radiation
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C13/00Assembling; Repairing; Cleaning
    • G02C13/008Devices specially adapted for cleaning contact lenses

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Optics & Photonics (AREA)
  • Eyeglasses (AREA)

Abstract

本发明公开了一种基于物理方法的角膜接触镜清洗消毒护理仪,包括外壳、水箱、紫外灯、微型排水泵、离心清洗部件、及控制电路;所述水箱用于盛水,其侧壁设有透明窗口,紫外灯设于透明窗口外,水箱中的水可由微型排水泵排出;离心清洗部件包括离心电机、旋转主支架、及固定于旋转主支架下的两只硅胶网状结构镜盒,离心电机通过旋转主支架带动两只镜盒旋转;该护理仪以水为清洗媒介,利用物理的方法对角膜接触镜进行清洗消毒杀菌,将角膜接触镜的深层清洁和消毒杀菌技术相结合,填补了国内外角膜接触镜绿色和环保消毒护理产品的空白。

The invention discloses a cleaning and disinfection care instrument for corneal contact lenses based on a physical method, which includes a housing, a water tank, an ultraviolet lamp, a micro drainage pump, a centrifugal cleaning component, and a control circuit; There is a transparent window, and the ultraviolet lamp is set outside the transparent window. The water in the water tank can be discharged by a micro drainage pump; the centrifugal cleaning parts include a centrifugal motor, a rotating main bracket, and two silicone mesh structure mirror boxes fixed under the rotating main bracket. The centrifugal motor drives the two mirror boxes to rotate by rotating the main bracket; the nursing device uses water as the cleaning medium to clean, disinfect and sterilize the contact lens with physical methods, and combines the deep cleaning and disinfection technology of the contact lens to fill Cleared the blank of domestic and foreign contact lens green and environmental protection disinfection care products.

Description

基于物理方法的角膜接触镜清洗消毒护理仪Contact lens cleaning and disinfection nursing device based on physical method

技术领域technical field

本发明属于角膜接触镜清洗、消毒技术领域,涉及一种角膜接触镜清洗消毒护理仪,尤其涉及一种基于物理方法的角膜接触镜清洗消毒护理仪。The invention belongs to the technical field of cleaning and disinfection of corneal contact lenses, and relates to a cleaning and disinfection nursing instrument for corneal contact lenses, in particular to a cleaning and disinfection nursing instrument for contact lenses based on physical methods.

背景技术Background technique

近视是我国最常见的眼部疾病,调查结果显示我国学生近视率已居世界第二位。小学生近视率为28%,初中生近视率为60%,高中生近视率为85%,大学生近视率为90%;男生14岁以上,女生13岁以上的近视不良率均超过80%。角膜接触镜(隐形眼镜)以其方便、舒适、美观等诸多优点被愈来愈多的患者尤其年轻人所喜爱,使用数量逐年增加;近年来越来越多的家长也倾向选择新型角膜接触镜(RGP、OK镜等)矫正青少年的近视及延缓近视发展,因此角膜接触镜的清洗、护理、消毒问题亟待关注。Myopia is the most common eye disease in my country, and the survey results show that the myopia rate of students in my country ranks second in the world. The myopia rate of primary school students is 28%, that of junior high school students is 60%, that of high school students is 85%, and that of college students is 90%. The rates of poor myopia for boys over the age of 14 and girls over the age of 13 are both over 80%. Contact lenses (contact lenses) are favored by more and more patients, especially young people, for their convenience, comfort, and aesthetics, and the number of use is increasing year by year; in recent years, more and more parents tend to choose new contact lenses (RGP, OK lens, etc.) to correct the myopia of young people and delay the development of myopia, so the cleaning, nursing and disinfection of contact lenses need to be paid attention to urgently.

目前角膜接触镜的清洁、消毒及护理,多采用化学的方法:即隐形眼镜护理液的反复冲洗、浸泡或除蛋白酶清洁镜片,普遍采用手反复揉搓和护理液的反复冲洗、浸泡或以除蛋白酶清洁镜片,易造成角膜接触镜的磨损、擦伤、破裂等。人们选择配戴角膜接触镜,意味着离不开各种各样的化学清洗液、消毒液和护理液。其成分复杂,如果一旦液体中有一种成分失效或者污染,则会带来眼部感染甚至失明的风险;此外,长期反复使用化学清洗消毒液还会引起眼表的各种疾病:如巨乳头性结膜炎、角膜知觉下降、干眼症等等。并且使用过的种种化学清洗液、消毒液和护理液的到处倾倒,也极大增加了对环境的污染。At present, the cleaning, disinfection and care of contact lenses mostly use chemical methods: that is, repeated washing, soaking or protease removal of contact lens care solution to clean the lens, and repeated hand rubbing and repeated washing and soaking of care solution or protease removal are generally used to clean the lens. Cleaning the lens can easily cause wear, scratches, cracks, etc. of the contact lens. People choose to wear contact lenses, which means that they cannot do without various chemical cleaning solutions, disinfectants and care solutions. Its components are complex, and if one of the components in the liquid fails or is contaminated, it will bring about the risk of eye infection or even blindness; in addition, repeated use of chemical cleaning and disinfecting solutions for a long time can also cause various diseases on the ocular surface: such as giant papillae Conjunctivitis, decreased corneal sensation, dry eye, etc. And the dumping of various chemical cleaning solutions, disinfectants and care solutions used has also greatly increased the pollution to the environment.

发明内容Contents of the invention

针对现有技术的不足,本发明提供一种基于物理方法的角膜接触镜清洗消毒护理仪,该护理仪以水为清洗媒介,利用物理的方法对角膜接触镜进行清洗消毒杀菌,将角膜接触镜的深层清洁和消毒杀菌技术相结合,填补了国内外角膜接触镜绿色和环保消毒护理产品的空白。Aiming at the deficiencies in the prior art, the present invention provides a contact lens cleaning and disinfection nursing instrument based on physical methods. The nursing instrument uses water as the cleaning medium, and uses physical methods to clean, disinfect and sterilize the contact lens, and the contact lens The combination of advanced deep cleaning and disinfection and sterilization technology fills the blank of domestic and foreign contact lens green and environmental protection disinfection care products.

本发明采用的技术方案如下:The technical scheme that the present invention adopts is as follows:

一种基于物理方法的角膜接触镜清洗消毒护理仪,包括外壳、水箱、紫外灯、微型排水泵、离心清洗部件、及控制电路;A contact lens cleaning and disinfection care instrument based on physical methods, including a housing, a water tank, an ultraviolet lamp, a micro drainage pump, centrifugal cleaning components, and a control circuit;

所述的外壳包括槽型底座、中框和上盖,水箱、紫外灯及微型排水泵均设置于槽型底座内,中框固定于底座上,且中框的镂空处正对水箱,上盖可打开地设于中框上方,关闭后上盖、中框与槽型底座之间形成密闭空间;The shell includes a trough-shaped base, a middle frame and an upper cover. The water tank, ultraviolet lamp and micro drainage pump are all arranged in the trough-shaped base, the middle frame is fixed on the base, and the hollow part of the middle frame is facing the water tank. It can be opened above the middle frame, and after closing, a closed space is formed between the upper cover, the middle frame and the groove base;

所述的水箱用于盛水,其侧壁设有透明窗口,紫外灯设于透明窗口外,水箱上设有出水口,该出水口与微型排水泵相连,微型排水泵的出水端与设于槽型底座上的排水口相连;The water tank is used to hold water, and its side wall is provided with a transparent window, and the ultraviolet lamp is arranged outside the transparent window. The drains on the grooved base are connected;

所述的离心清洗部件包括离心电机、旋转主支架、及固定于旋转主支架下的两只硅胶网状结构镜盒,离心电机设置于上盖底面,旋转主支架与离心电机的输出轴固定连接;The centrifugal cleaning part includes a centrifugal motor, a rotating main support, and two mirror boxes of silica gel mesh structure fixed under the rotating main support. The centrifugal motor is arranged on the bottom surface of the upper cover, and the rotating main support is fixedly connected to the output shaft of the centrifugal motor. ;

控制电路控制离心电机、紫外灯、微型排水泵的工作。The control circuit controls the work of the centrifugal motor, the ultraviolet lamp and the miniature drainage pump.

上述技术方案中,进一步的,所述的硅胶网状结构镜盒为硅胶材质、网状结构的镂空镜盒,用于放置角膜接触镜。In the above technical solution, further, the silicone mesh mirror box is a hollow mirror box made of silicone material and a mesh structure, which is used for placing corneal contact lenses.

进一步的,所述的两只硅胶网状结构镜盒分设于旋转主支架的两端。Further, the two silica gel mesh structure mirror boxes are respectively arranged at the two ends of the rotating main bracket.

进一步的,所述的透明窗口采用石英玻璃。Further, the transparent window is made of quartz glass.

更进一步的,所述的水箱两侧壁均设有石英玻璃透明窗口,每个透明窗口外设置一只紫外灯。Further, both sides of the water tank are provided with quartz glass transparent windows, and an ultraviolet lamp is arranged outside each transparent window.

进一步的,所述的消毒护理仪上设置有LED指示灯,用于显示工作状态。Further, the said disinfection nursing instrument is provided with LED indicator lights for displaying the working status.

进一步的,所述的消毒护理仪上设置有控制按钮,按下后护理仪自动进行如下工作:离心电机正向、反向交替旋转一定时间后,紫外灯亮起,微型排水泵工作,再过一段时间后,紫外灯关闭,离心电机停止旋转。Further, the disinfection nursing instrument is provided with a control button, and after being pressed, the nursing instrument automatically performs the following work: After the centrifugal motor rotates forward and reverse alternately for a certain period of time, the ultraviolet lamp lights up, the micro drainage pump works, and after a period of After the time, the UV lamp is turned off and the centrifuge motor stops rotating.

更进一步的,所述的离心电机旋转的速度为2次正反转运动/秒,在旋转3分钟后,紫外灯点亮,微型排水泵启动,再过3分钟后,紫外灯关闭,离心电机停止旋转。Furthermore, the rotation speed of the centrifugal motor is 2 forward and reverse motions per second. After 3 minutes of rotation, the ultraviolet lamp is lit, and the micro drainage pump is started. After another 3 minutes, the ultraviolet lamp is turned off, and the centrifugal motor Stop spinning.

更进一步的,所述的紫外灯的总功率为12W。Further, the total power of the ultraviolet lamp is 12W.

进一步的,所述的控制电路基于单片机实现。Further, the control circuit is implemented based on a single-chip microcomputer.

本发明的有益效果是:The beneficial effects of the present invention are:

本发明的护理仪是一种全新的角膜接触镜清洗消毒护理仪器,该仪器以水为清洗媒介利用物理的方法对角膜接触镜进行清洗消毒杀菌,将角膜接触镜的深层清洁和消毒杀菌技术相结合,可实现自动化控制,在整个清洗、消毒的过程中,不需要用手去接触镜片,有效防止了镜片的二次污染,且整个过程为纯物理过程,不涉及化学品的使用和污染,填补了国内外角膜接触镜绿色和环保消毒护理产品的空白。The nursing instrument of the present invention is a brand-new cleaning and disinfection nursing instrument for contact lenses. The instrument uses water as the cleaning medium to clean, disinfect and sterilize the contact lenses with physical methods, and combines the deep cleaning and disinfection technologies of the contact lenses. Combined, automatic control can be realized. During the whole process of cleaning and disinfection, there is no need to touch the lens with hands, which effectively prevents the secondary pollution of the lens, and the whole process is a purely physical process, which does not involve the use and pollution of chemicals. It fills the blank of domestic and foreign contact lens green and environmental protection disinfection care products.

本发明的护理仪清洗效果明显优于市售超声波清洗机,经过3分钟时间的清洗,用高倍显微镜在裂隙灯光源的环境下观察,任何镜片在定位弧、基弧、反转弧等处均无明显脂质、蛋白等泪分泌沉淀。The cleaning effect of the nursing instrument of the present invention is obviously better than that of the commercially available ultrasonic cleaning machine. After 3 minutes of cleaning, observe under the environment of the slit lamp light source with a high-power microscope, any lens can be seen at the positioning arc, base arc, inversion arc, etc. No obvious lipid, protein and other lacrimal secretion precipitation.

本发明的护理仪消毒效果优异,能够有效杀灭控制微生物,且与市面上角膜接触镜清洗仪不同,由于本护理仪使用水为媒介来进行清洗,在杀灭微生物的同时无任何清洗剂残留。The nursing device of the present invention has an excellent disinfection effect, can effectively kill and control microorganisms, and is different from the corneal contact lens cleaners on the market, because the nursing device uses water as a medium for cleaning, and there is no cleaning agent residue while killing microorganisms .

本发明的护理仪可以清洗任何类型的角膜接触镜,无需专用护理液,其兼容性极强。The care instrument of the invention can clean any type of corneal contact lens without special care solution, and has strong compatibility.

可以看出,本发明的护理仪将引领新一代角膜接触镜清洗消毒产品的发展。It can be seen that the nursing device of the present invention will lead the development of a new generation of contact lens cleaning and disinfection products.

附图说明Description of drawings

图1是本发明护理仪的一种具体结构示意图;Fig. 1 is a kind of specific structural representation of nursing apparatus of the present invention;

图2是离心清洗部件的一种具体结构示意图;Fig. 2 is a kind of specific structural representation of centrifugal cleaning part;

图3是硅胶网状结构镜盒的一种具体结构示意图;Fig. 3 is a kind of specific structural schematic diagram of silica gel mesh structure mirror box;

图4是水箱的一种具体结构示意图;Fig. 4 is a kind of specific structural representation of water tank;

图5是控制电路的一种具体结构示意图。Fig. 5 is a specific structural schematic diagram of the control circuit.

具体实施方式Detailed ways

下面结合附图对本发明的技术方案做进一步说明。The technical solution of the present invention will be further described below in conjunction with the accompanying drawings.

1.护理仪的结构设计及运行控制1. Structural design and operation control of the nursing instrument

本发明的护理仪包括外壳、水箱、紫外灯、微型排水泵、离心清洗部件、及控制电路;如图1所示,为本发明护理仪的一种具体结构,该实例仅用于对本发明方案进行说明解释而并非对本发明范围的限定。在该例中,护理仪包括:外壳底座1、12瓦紫外灯的整流器2、微型排水泵3、电源开关4、两支紫外灯管(每支6瓦)5、水箱6、中框(带有启动按钮和LED指示灯)7、pcb电路板8、两个硅胶网状结构镜盒9、旋转主支架10、离心电机11、上盖12;中框7固定于底座1上,且中框7的镂空处正对水箱6,上盖12设于中框7上方,关闭后上盖12、中框7与底座1之间形成密闭空间;水箱6用于盛水,其两个侧壁设有透明窗口(如图4),透明窗口采用对紫外线透过率达95%的石英玻璃,厚度0.8mm,每个透明窗口外各设一支紫外灯5,水箱上设有出水口,该出水口与微型排水泵3相连,微型排水泵3的出水端与设于底座1上的排水口相连,如图2,离心电机11设置于上盖12底面,旋转主支架10与离心电机11的输出轴固定连接;两个硅胶网状结构镜盒9分别安装在旋转主支架两端下方,硅胶网状结构镜盒9的结构如图3所示,Nursing instrument of the present invention comprises shell, water tank, ultraviolet lamp, miniature drainage pump, centrifugal cleaning part, and control circuit; As shown in Figure 1, is a kind of specific structure of nursing instrument of the present invention, and this example is only used for the scheme of the present invention They are presented by way of illustration and not limitation of the scope of the invention. In this example, the nursing instrument includes: shell base 1, rectifier 2 of 12-watt ultraviolet lamp, miniature drainage pump 3, power switch 4, two ultraviolet lamp tubes (each 6 watts) 5, water tank 6, middle frame (with There are start button and LED indicator light) 7, pcb circuit board 8, two mirror boxes of silica gel mesh structure 9, rotating main bracket 10, centrifugal motor 11, upper cover 12; the middle frame 7 is fixed on the base 1, and the middle frame The hollow part of 7 faces the water tank 6, and the loam cake 12 is arranged on the top of the middle frame 7. After closing, an airtight space is formed between the loam cake 12, the middle frame 7 and the base 1; the water tank 6 is used for holding water, and its two side walls are provided with Transparent window (as Fig. 4) is arranged, and transparent window adopts the quartz glass that UV transmittance reaches 95%, thickness 0.8mm, respectively establishes an ultraviolet lamp 5 outside each transparent window, is provided with water outlet on the water tank, this outlet The water outlet is connected to the micro drainage pump 3, and the water outlet of the micro drainage pump 3 is connected to the drainage port located on the base 1, as shown in Fig. The shaft is fixedly connected; two silicone mesh structure mirror boxes 9 are respectively installed under the two ends of the rotating main support, and the structure of the silicone mesh structure mirror box 9 is shown in Figure 3.

pcb电路板8上设置控制电路控制离心电机、紫外灯、微型排水泵的工作。本发明基于旋转离心方法,由于镜片的质量很小,所以只需提供1~3瓦直流电功率就足够了,旋转频率经多次反复试验以2次正转反转/秒为最佳,清洗时间经多次反复试验观察,以3分钟/次为最好,在高倍显微镜观察无眼液蛋白、脂质残留。图5为一种具体的控制电路结构,其中:FU是保险丝,BTA是3安培双向可控硅,T1是五瓦5V开关电源,D1-3是LED指示灯,B是12瓦紫外灯整流器,MOC4041是可控硅触发光耦,Q1-2是AO3401场效应晶体管,Q3-6是AO3400场效应晶体管,M1是离心电机,M2是微型排水泵电机,R1、9、10是1K电阻,R2~7是10k电阻,R8是10欧电阻,R11~16是100k电阻,R17是2.2k电阻,R18、19是120k电阻。电路工作过程如下:安下AN1按钮,单片机pic12f683开始工作,由7脚发出2转/秒的工作信号经过D6、R4、R6、Q5触发由Q1、2、3、4组成的“H”工作,从而使得电机M1工作,可以使镜片在硅胶网状结构镜盒内在纯净水中反复清洗3分钟,3分钟后单片机第3脚、第2脚分别给出输出信号,驱动M2放尽水箱中的水,同时打开紫外线,对镜片进行甩干脱水消毒。设定时间一到,就关闭镜片甩干、消毒系统。The pcb circuit board 8 is provided with a control circuit to control the work of the centrifugal motor, the ultraviolet lamp and the miniature drainage pump. The present invention is based on the rotary centrifugal method. Since the mass of the lens is very small, it is enough to provide only 1 to 3 watts of direct current power. After repeated tests, the rotation frequency is 2 forward and reverse rotations per second. The cleaning time After many repeated tests and observations, 3 minutes/time is the best, and there is no protein and lipid residue in eye fluid under high-power microscope observation. Figure 5 is a specific control circuit structure, wherein: FU is a fuse, BTA is a 3-amp triac, T1 is a five-watt 5V switching power supply, D1-3 is an LED indicator light, and B is a 12-watt ultraviolet lamp rectifier. MOC4041 is a thyristor trigger optocoupler, Q1-2 is AO3401 field effect transistor, Q3-6 is AO3400 field effect transistor, M1 is a centrifugal motor, M2 is a micro drainage pump motor, R1, 9, 10 are 1K resistors, R2~ 7 is a 10k resistor, R8 is a 10 ohm resistor, R11~16 is a 100k resistor, R17 is a 2.2k resistor, and R18 and 19 are 120k resistors. The working process of the circuit is as follows: put down the AN1 button, the single chip microcomputer pic12f683 starts to work, and the working signal of 2 revolutions per second is sent out from pin 7, and the "H" work composed of Q1, 2, 3 and 4 is triggered by D6, R4, R6 and Q5. So that the motor M1 works, and the lens can be repeatedly cleaned in pure water for 3 minutes in the silica gel mesh structure mirror box. After 3 minutes, the 3rd pin and the 2nd pin of the single chip microcomputer give output signals respectively, and drive M2 to drain the water in the water tank. At the same time, the ultraviolet light is turned on, and the lens is dried, dehydrated and disinfected. Once the set time is up, the lens drying and disinfection system will be turned off.

上述护理仪的整个操作过程如下:将待洗镜片分别安放在硅胶网状结构镜盒9内,在水箱6中放入100ml纯净水,盖上上盖12,插好电源,开启电源开关k,在中框上的LED会有指示,再按下AN启动按钮键,离心电机就会控制镜片在水箱中作2次/秒的正、反转运行;3分钟后,仪器自动会把水箱中的100ml纯净水排放出仪器外;同时,两支紫外灯管会自动点亮,此时离心电机仍在不停运转,在运转过程中,镜片的各个部位都会受到紫外线照射,同时在离心力的作用下,镜片上残留的水滴会被彻底甩干。再过3分钟后,仪器自动关闭紫外灯、离心电机也停止旋转,此时,角膜接触镜清洗消毒完毕。The whole operation process of the above-mentioned nursing device is as follows: place the lenses to be washed in the silica gel mesh structure mirror box 9 respectively, put 100ml of pure water in the water tank 6, cover the upper cover 12, plug in the power supply, turn on the power switch k, The LED on the middle frame will have an indication, and then press the AN start button, the centrifugal motor will control the lens to perform forward and reverse operation 2 times per second in the water tank; after 3 minutes, the instrument will automatically turn the lens in the water tank 100ml of pure water is discharged out of the instrument; at the same time, the two ultraviolet lamps will automatically light up, and the centrifugal motor is still running at this time. During the operation, all parts of the lens will be irradiated by ultraviolet rays. , the remaining water droplets on the lens will be completely dried. After another 3 minutes, the instrument automatically turns off the ultraviolet lamp and the centrifugal motor stops rotating. At this time, the cleaning and disinfection of the contact lens is completed.

2.护理仪的清洗消毒效果验证2. Verification of the cleaning and disinfection effect of the nursing instrument

选取目前市面上的一款角膜接触镜清洗仪与本发明的护理仪进行清洗消毒实验,采用生物指示剂抗性试验来进行验证。A contact lens cleaning instrument currently on the market and the nursing instrument of the present invention are selected to carry out cleaning and disinfection experiments, and a biological indicator resistance test is used for verification.

所采用的微生物有:The microorganisms used are:

细菌:金黄色葡萄球菌ATCC25923、铜绿假单胞菌ATCC27853、肺炎链球菌ATCC49619、表皮葡萄球菌;Bacteria: Staphylococcus aureus ATCC25923, Pseudomonas aeruginosa ATCC27853, Streptococcus pneumoniae ATCC49619, Staphylococcus epidermidis;

真菌:白色念珠菌ATCC14053、镰刀霉;Fungi: Candida albicans ATCC14053, Fusarium;

其中,金黄色葡萄球菌、铜绿假单胞菌、肺炎链球菌、白色念珠菌均为浙江大学医学院附属第一医院保存的标准菌株,表皮葡萄球菌、镰刀霉为浙江大学医学院附属第一医院实验室检出的临床菌株,均来自角膜刮片分泌物。Among them, Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumoniae, and Candida albicans were all standard strains preserved in the First Affiliated Hospital of Zhejiang University School of Medicine; The clinical strains detected in the laboratory all came from the secretion of corneal scrapings.

以金黄色葡萄球菌为例,试验流程如下:Taking Staphylococcus aureus as an example, the test procedure is as follows:

将灭菌的角膜接触镜镜片分为6组,每组重复六个镜片,将金黄色葡萄球菌的新鲜培养物(18~24小时)用无菌盐水调浊度至0.5Mcf,相当于108cfu/ml的菌悬液。滴染菌悬液10ul于已灭菌的镜片上,并用无菌滴管吸掉多余菌液,静置干燥后备用。Divide the sterilized contact lens lenses into 6 groups, each group repeats six lenses, adjust the turbidity of the fresh culture of Staphylococcus aureus (18-24 hours) to 0.5Mcf with sterile saline, which is equivalent to 10 8 cfu/ml bacterial suspension. Drop 10ul of the bacterial suspension on the sterilized lens, suck off the excess bacterial solution with a sterile dropper, let it dry and set it aside for later use.

(1)阴性对照组:不做任何处理(1) Negative control group: no treatment

(2)阳性对照组:滴染菌悬液,不做清洗(2) Positive control group: drop staining with bacterial suspension, without washing

(3)标准清洗组:用温和中性肥皂洗手后,放在手掌心并滴上4滴博视顿新洁护理液于镜上,小心搓擦镜片两面20秒,用博视顿新洁冲洗镜片5秒。(3) Standard cleaning group: After washing hands with mild neutral soap, put 4 drops of Boston Cleansing Care Solution on the palm of your hand and put it on the mirror. Carefully rub both sides of the lens for 20 seconds, then rinse with Bostons Cleansing Lens for 5 seconds.

(4)对照清洗仪(即市面角膜接触镜清洗仪)护理液清洗组:安置镜片,放入博视顿新洁护理液,电源,开启,按该清洗仪标准流程清洗镜片后,取出镜片。(4) Care solution cleaning group of the comparison cleaning device (that is, the corneal contact lens cleaning device in the market): place the lens, put in Boston's new cleaning care solution, power on, turn on, clean the lens according to the standard procedure of the cleaning device, and then take out the lens.

(5)对照清洗仪(即市面角膜接触镜清洗仪)纯净水清洗组:安置镜片,放入纯净水,电源,开启,按该清洗仪标准流程清洗镜片后,取出镜片。(5) Compared with the cleanser (that is, the corneal contact lens cleaner on the market) pure water cleaning group: place the lens, put in pure water, turn on the power, clean the lens according to the standard procedure of the cleaner, and then take out the lens.

(6)本发明护理仪清洗组:(6) Nursing instrument cleaning group of the present invention:

将镜片安放在护理仪中,加入100ml的纯净水,合上盖子后接通电源,按下清洗开关即可。经3分钟清洗后,水由仪器下方排水管排出,机器自行启动内部功率为12W的紫外灯照射3分钟,整体工作时间为6分钟,结束后取出镜片。Place the lens in the care device, add 100ml of pure water, close the lid, turn on the power, and press the cleaning switch. After 3 minutes of cleaning, the water is discharged from the drain pipe under the instrument, and the machine automatically starts the UV lamp with an internal power of 12W to irradiate for 3 minutes. The overall working time is 6 minutes, and the lens is taken out after the end.

分组清洗结束后将角膜接触镜置于2ml普通营养肉汤(杭州天和)中,于35℃±1℃恒温培养箱中培养18~24小时,观察肉汤浑浊情况。同时取10ul肉汤接种在哥伦比亚血琼脂平板(法国生物梅利埃)上观察生长菌落是否为接种菌。按上述流程分别进行金黄色葡萄球菌、表皮葡萄球菌,铜绿假单胞菌,肺炎链球菌,白色念珠菌的试验。对于镰刀霉则采用如下方法:将灭菌处理后的镜片与镰刀霉新鲜培养物接触作用一定时间后认为污染成功,根据上述分组情况分别处理每组镜片,清洗结束后用镜片直接涂抹于沙保氏培养基(郑州博赛)上,于35℃培养箱中培养18~24小时观察结果。After group cleaning, put the corneal contact lens in 2ml of ordinary nutrient broth (Hangzhou Tianhe) and incubate in a constant temperature incubator at 35°C±1°C for 18-24 hours, and observe the turbidity of the broth. At the same time, 10 ul of the broth was inoculated on a Columbia blood agar plate (Bio-Mélieux, France) to observe whether the growing colony was the inoculum. Tests on Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Streptococcus pneumoniae and Candida albicans were carried out according to the above procedure. For Fusarium mold, the following method is adopted: contact the sterilized lens with the fresh culture of Fusarium mold for a certain period of time, and then consider that the contamination is successful, treat each group of lenses separately according to the above grouping conditions, and apply the lens directly on the sand protection after cleaning. cultured in a 35°C incubator for 18-24 hours to observe the results.

将6种控制微生物每种重复试验6次,每次两只镜片,共72次清洗。通过外观观察(清洗液残留),肉汤培养(肉汤浑浊度)和平板培养(是否为接种菌)等几个标准来衡量几种清洗方法的清洗效果,无菌生长为合格,计算合格率见表1。Each of the 6 control microorganisms was tested 6 times, two lenses each time, and a total of 72 cleanings were performed. The cleaning effect of several cleaning methods is measured by several standards such as appearance observation (cleaning solution residue), broth culture (broth turbidity) and plate culture (whether it is inoculated bacteria), and the aseptic growth is qualified, and the qualified rate is calculated See Table 1.

表1不同清洗组角膜接触镜清洗效果比较Table 1 Comparison of cleaning effects of different cleaning groups for contact lenses

注:*72次清洗中经外观观察清洗液残留数为72例;Note: *72 cases of residual cleaning solution were observed in 72 times of cleaning;

△72次清洗中经肉汤培养2例肉汤浑浊;△ 2 cases of broth cultured in 72 washes were turbid;

▲72次清洗中经平板培养2例有细菌生长,且生长菌为接种菌。▲Bacteria grew in 2 cases after plate culture in 72 times of cleaning, and the growing bacteria were inoculum bacteria.

Claims (10)

1. a kind of contact lens cleaning and sterilizing care instrument based on physical method, which is characterized in that including shell, water tank, purple Outer lamp, micro-drainage pump, eccentric cleaning component and control circuit;
The shell includes groove profile pedestal, center and upper cover, and water tank, ultraviolet lamp and micro-drainage pump are all set in groove profile pedestal Interior, center is fixed on pedestal, and the hollow part face water tank of center, and upper cover is openably set to above center, after closing on Confined space is formed between lid, center and groove profile pedestal;
For the water tank for being filled with water, side wall is equipped with transparent window, and ultraviolet lamp is set to outside transparent window, and water tank is equipped with water outlet Mouthful, which is connected with micro-drainage pump, and the water outlet of micro-drainage pump is connected with the discharge outlet being set on groove profile pedestal;
The eccentric cleaning component includes two silica gel for being centrifuged motor, rotation main support and being fixed under rotation main support Reticular structure mirror case, centrifugation motor are set to upper cover bottom surface, and rotation main support is fixedly connected with the output shaft for being centrifuged motor;
The work of control circuit control centrifugation motor, ultraviolet lamp, micro-drainage pump.
2. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that institute The silica gel reticular structure mirror case stated is the hollow out mirror case of silica gel material, reticular structure, for placing contact lens.
3. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that institute The two silica gel reticular structure mirror cases stated are divided into the both ends of rotation main support.
4. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that institute The transparent window stated uses quartz glass.
5. the contact lens cleaning and sterilizing care instrument according to claim 4 based on physical method, which is characterized in that institute The water tank two sidewalls stated are equipped with quartz glass transparent window, and a ultraviolet lamp is arranged outside each transparent window.
6. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that institute It is provided with LED light on the disinfection nursing instrument stated, is used for display working condition.
7. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that institute Be provided with control button on the disinfection nursing instrument stated, press rear care instrument and worked as follows automatically: centrifugation motor is positive, reversed It is alternately rotated after a certain period of time, ultraviolet lamp lights, micro-drainage pump work, then after a period of time, ultraviolet lamp is closed, centrifugation electricity Machine stops rotating.
8. the contact lens cleaning and sterilizing care instrument according to claim 7 based on physical method, which is characterized in that institute The speed for the centrifugation motor rotation stated is 2 positive and negative rotation campaign/seconds, and after rotation 3 minutes, ultraviolet lamp is lighted, micro-drainage pump Starting, after 3 minutes, ultraviolet lamp is closed, and centrifugation motor stops rotating.
9. the contact lens cleaning and sterilizing care instrument according to claim 8 based on physical method, which is characterized in that institute The general power for the ultraviolet lamp stated is 12W.
10. the contact lens cleaning and sterilizing care instrument according to claim 1 based on physical method, which is characterized in that The control circuit is based on chip microcontroller.
CN201910441974.6A 2019-05-24 2019-05-24 Contact lens cleaning and sterilizing care instrument based on physical method Pending CN110095887A (en)

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Publication number Priority date Publication date Assignee Title
CN111505840A (en) * 2020-06-04 2020-08-07 武汉德邻莳海科技发展有限公司 An automatic cleaning instrument for orthokeratology lenses
CN112974454A (en) * 2021-04-25 2021-06-18 长沙迈博光电有限公司 Cleaning device for cleaning optical lens
CN113419360A (en) * 2021-06-23 2021-09-21 武汉爱尔眼科汉口医院有限公司 Investigation and intervention measure for pollution condition of cornea shaping mirror try-on piece
CN113885226A (en) * 2021-11-09 2022-01-04 苏州求同生物科技有限公司 Automatic neutralization device for deep cleaning of hard orthokeratology lens

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CN109212784A (en) * 2018-10-23 2019-01-15 杭州视亨光电有限公司 Automatic intelligent hydrodynamic force contact lens cleaning machine
CN210605248U (en) * 2019-05-24 2020-05-22 杭州视亨光电有限公司 Corneal contact lens cleaning and disinfecting nursing instrument based on physical method

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CN102274539A (en) * 2011-08-02 2011-12-14 杭州博士顿光学有限公司 Nursing instrument for corneal contact lens
CN106490805A (en) * 2016-12-09 2017-03-15 圆融健康科技(深圳)有限公司 Contact lens case
CN109212784A (en) * 2018-10-23 2019-01-15 杭州视亨光电有限公司 Automatic intelligent hydrodynamic force contact lens cleaning machine
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111505840A (en) * 2020-06-04 2020-08-07 武汉德邻莳海科技发展有限公司 An automatic cleaning instrument for orthokeratology lenses
CN112974454A (en) * 2021-04-25 2021-06-18 长沙迈博光电有限公司 Cleaning device for cleaning optical lens
CN113419360A (en) * 2021-06-23 2021-09-21 武汉爱尔眼科汉口医院有限公司 Investigation and intervention measure for pollution condition of cornea shaping mirror try-on piece
CN113885226A (en) * 2021-11-09 2022-01-04 苏州求同生物科技有限公司 Automatic neutralization device for deep cleaning of hard orthokeratology lens

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