CN110051770B - Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof - Google Patents
Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof Download PDFInfo
- Publication number
- CN110051770B CN110051770B CN201910449133.XA CN201910449133A CN110051770B CN 110051770 B CN110051770 B CN 110051770B CN 201910449133 A CN201910449133 A CN 201910449133A CN 110051770 B CN110051770 B CN 110051770B
- Authority
- CN
- China
- Prior art keywords
- parts
- servings
- preparation
- herbal medicine
- chinese herbal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract description 33
- 238000002360 preparation method Methods 0.000 title claims abstract description 32
- 241000411851 herbal medicine Species 0.000 title claims abstract description 27
- 230000000091 immunopotentiator Effects 0.000 title description 12
- 239000003814 drug Substances 0.000 claims abstract description 24
- 241000218671 Ephedra Species 0.000 claims abstract description 13
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 13
- 244000144730 Amygdalus persica Species 0.000 claims abstract description 10
- 241000132012 Atractylodes Species 0.000 claims abstract description 10
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 10
- 235000006040 Prunus persica var persica Nutrition 0.000 claims abstract description 10
- 241001289529 Fallopia multiflora Species 0.000 claims abstract description 8
- 235000006533 astragalus Nutrition 0.000 claims abstract description 8
- 229940079593 drug Drugs 0.000 claims abstract description 8
- 230000036039 immunity Effects 0.000 claims abstract description 5
- 241000748223 Alisma Species 0.000 claims abstract 3
- 241001061264 Astragalus Species 0.000 claims abstract 3
- 235000002722 Dioscorea batatas Nutrition 0.000 claims abstract 3
- 235000006536 Dioscorea esculenta Nutrition 0.000 claims abstract 3
- 240000001811 Dioscorea oppositifolia Species 0.000 claims abstract 3
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 claims abstract 3
- 244000170916 Paeonia officinalis Species 0.000 claims abstract 3
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims abstract 3
- 210000004233 talus Anatomy 0.000 claims abstract 3
- 238000009835 boiling Methods 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 14
- 241000245665 Taraxacum Species 0.000 claims description 12
- 238000000605 extraction Methods 0.000 claims description 9
- 241000007126 Codonopsis pilosula Species 0.000 claims description 7
- 239000000706 filtrate Substances 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 239000007788 liquid Substances 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 240000003173 Drymaria cordata Species 0.000 claims 1
- 240000004370 Pastinaca sativa Species 0.000 claims 1
- 235000017769 Pastinaca sativa subsp sativa Nutrition 0.000 claims 1
- 241000745988 Phyllostachys Species 0.000 claims 1
- 230000002708 enhancing effect Effects 0.000 claims 1
- 238000010298 pulverizing process Methods 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 210000004185 liver Anatomy 0.000 abstract description 7
- 235000021050 feed intake Nutrition 0.000 abstract description 4
- 210000003734 kidney Anatomy 0.000 abstract description 4
- 239000000126 substance Substances 0.000 abstract description 4
- 210000004369 blood Anatomy 0.000 abstract description 2
- 239000008280 blood Substances 0.000 abstract description 2
- 230000006870 function Effects 0.000 abstract description 2
- 238000000034 method Methods 0.000 abstract description 2
- 230000008569 process Effects 0.000 abstract description 2
- 241000756943 Codonopsis Species 0.000 abstract 1
- 241000287828 Gallus gallus Species 0.000 abstract 1
- 240000001949 Taraxacum officinale Species 0.000 abstract 1
- 244000144972 livestock Species 0.000 abstract 1
- 241000282898 Sus scrofa Species 0.000 description 9
- 230000000694 effects Effects 0.000 description 9
- 244000281702 Dioscorea villosa Species 0.000 description 7
- 241001106477 Paeoniaceae Species 0.000 description 7
- 244000197580 Poria cocos Species 0.000 description 7
- 235000008599 Poria cocos Nutrition 0.000 description 7
- 241000282887 Suidae Species 0.000 description 7
- 230000017260 vegetative to reproductive phase transition of meristem Effects 0.000 description 7
- 206010037660 Pyrexia Diseases 0.000 description 6
- 238000002156 mixing Methods 0.000 description 6
- 241000045403 Astragalus propinquus Species 0.000 description 5
- 241000112528 Ligusticum striatum Species 0.000 description 5
- 241001180876 Saposhnikovia Species 0.000 description 5
- 230000003907 kidney function Effects 0.000 description 5
- 230000003908 liver function Effects 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 238000000227 grinding Methods 0.000 description 4
- 238000008157 ELISA kit Methods 0.000 description 2
- 241000212322 Levisticum officinale Species 0.000 description 2
- 235000001188 Peltandra virginica Nutrition 0.000 description 2
- 240000001341 Reynoutria japonica Species 0.000 description 2
- 235000018167 Reynoutria japonica Nutrition 0.000 description 2
- 241000913745 Spatholobus Species 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 229940107666 astragalus root Drugs 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000007599 discharging Methods 0.000 description 2
- 239000003651 drinking water Substances 0.000 description 2
- 235000020188 drinking water Nutrition 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 239000001645 levisticum officinale Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000002791 soaking Methods 0.000 description 2
- 208000020401 Depressive disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000012674 herbal formulation Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 201000003102 mental depression Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/17—Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/884—Alismataceae (Water-plantain family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
本发明公开了一种用于治疗体弱仔猪的复方中草药免疫增强制剂，按重量份数计包括：党参10‑50份，炒白术5‑15份，淮山药10‑50份，赤芍1‑15份，碧桃干10‑50份，麻黄根10‑50份，茯苓10‑30份，泽泻10‑30份，生黄芪10‑30份，川芎10‑20份，何首乌10‑30份，鸡血藤10‑40份，蒲公英10‑40份，防风1‑15份；本发明的复方中草药制剂具有明显恢复体弱仔猪体质，增加采食量，保肝护肾，提高免疫力等的作用，该制剂可以替代部分化学药物，达到治疗体弱仔猪的目的，工艺简单，对设备要求低，易实施，所制得的复方中草药制剂饲喂方便，无毒、无害、无残留，安全性好，能满足人们对无公害畜产品的需求。The invention discloses a compound Chinese herbal medicine immune-enhancing preparation for treating weak piglets, comprising in parts by weight: 10-50 parts of Codonopsis Radix, 5-15 parts of fried Atractylodes, 10-50 parts of Chinese yam medicine, 1-5 parts of red peony root 15 servings, 10-50 servings of dried peaches, 10-50 servings of ephedra root, 10-30 servings of Poria, 10-30 servings of Alisma, 10-30 servings of raw Astragalus, 10-20 servings of Chuanxiong, 10-30 servings of Polygonum multiflorum, chicken 10-40 parts of blood vine, 10-40 parts of dandelion, 1-15 parts of windproof; the compound Chinese herbal medicine preparation of the invention has the functions of obviously restoring the physique of weak piglets, increasing feed intake, protecting liver and kidney, improving immunity, etc. The preparation can replace some chemical drugs to achieve the purpose of treating weak piglets, the process is simple, the equipment requirements are low, and the implementation is easy. , to meet people's demand for pollution-free livestock products.
Description
Technical Field
The invention relates to a compound Chinese herbal medicine immunopotentiator for treating weak piglets and a preparation method thereof, belonging to the technical field of traditional Chinese medicines.
Background
Poor immunity and weakness of piglets are typical characteristics under intensive pig raising production conditions, and the piglets grow slowly and have low breeding survival rate due to low appetite and poor liver and kidney functions of the weak piglets. At present, most pig farms are treated by chemical medicines, which can improve the constitution of piglets but can also cause medicine residues. Therefore, a compound Chinese herbal medicine immunopotentiator for treating weak piglets and a preparation method thereof are provided.
Disclosure of Invention
The invention mainly aims to provide a compound Chinese herbal medicine immunopotentiator for treating physically weak piglets and a preparation method thereof, which have the effects of obviously recovering the physical fitness of the physically weak piglets, increasing the feed intake, protecting the liver and the kidney, improving the immunity and the like, can replace partial chemical medicines, achieve the purpose of treating the physically weak piglets, and can effectively solve the problems in the background technology.
In order to achieve the purpose, the invention adopts the technical scheme that:
a compound Chinese herbal medicine immunopotentiator for treating weak piglets comprises the following components in parts by weight: 10-50 parts of codonopsis pilosula, 5-15 parts of fried bighead atractylodes rhizome, 10-50 parts of common yam rhizome, 1-15 parts of red paeony root, 10-50 parts of dried flowering peach, 10-50 parts of ephedra root, 10-30 parts of poria cocos, 10-30 parts of rhizoma alismatis, 10-30 parts of raw astragalus membranaceus, 10-20 parts of ligusticum wallichii, 10-30 parts of polygonum multiflorum, 10-40 parts of caulis spatholobi, 10-40 parts of dandelion and 1-15 parts of radix sileris.
The invention also provides a preparation method of the compound Chinese herbal medicine immunopotentiator for treating the weak piglets, which comprises the following steps:
(1) mixing radix codonopsitis, fried bighead atractylodes rhizome, common yam rhizome, red paeony root, dried flowering peach, tuckahoe, rhizoma alismatis, raw astragalus root, szechuan lovage rhizome, tuber fleeceflower root, suberect spatholobus stem, divaricate saposhnikovia root and the like according to the parts by weight, and carrying out superfine grinding on the mixture to obtain mixed traditional Chinese medicine superfine powder;
(2) micronizing radix Ephedrae and herba Taraxaci separately;
(3) after superfine grinding, respectively soaking the mixed traditional Chinese medicine superfine powder, the ephedra root superfine powder and the dandelion superfine powder in 10 times of water for 1 hour;
(4) placing radix Ephedrae micropowder into Chinese medicinal extraction tank, boiling, maintaining slightly boiling state for 0.5 hr, placing mixed Chinese medicinal micropowder into Chinese medicinal extraction tank, boiling, maintaining slightly boiling state for 1.5 hr, placing herba Taraxaci micropowder into Chinese medicinal extraction tank, boiling, and maintaining slightly boiling state for 1 hr;
(5) respectively discharging the liquid, filtering, adding 4 times of water into the residue, continuing decocting according to the above steps for three times, mixing the three filtrates, mixing the filtrates of the mixed traditional Chinese medicine, radix Ephedrae and herba Taraxaci, concentrating at 50-60 deg.C until the concentration of crude drug is 0.1g/mL, bottling, and sterilizing to obtain the Chinese herbal medicine compound preparation.
The compound Chinese herbal medicine preparation has the effects of obviously recovering the physique of the physically weak piglets, increasing the feed intake, protecting the liver and the kidney, improving the immunity and the like, can replace partial chemical medicines, achieves the aim of treating the physically weak piglets, has simple process, low equipment requirement and easy implementation, is convenient to feed, is non-toxic, harmless and residue-free, has good safety, and can meet the requirements of people on pollution-free animal products.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
A compound Chinese herbal medicine immunopotentiator for treating weak piglets comprises the following components in parts by weight: 10-50 parts of codonopsis pilosula, 5-15 parts of fried bighead atractylodes rhizome, 10-50 parts of common yam rhizome, 1-15 parts of red paeony root, 10-50 parts of dried flowering peach, 10-50 parts of ephedra root, 10-30 parts of poria cocos, 10-30 parts of rhizoma alismatis, 10-30 parts of raw astragalus membranaceus, 10-20 parts of ligusticum wallichii, 10-30 parts of polygonum multiflorum, 10-40 parts of caulis spatholobi, 10-40 parts of dandelion and 1-15 parts of radix sileris.
The invention also provides a preparation method of the compound Chinese herbal medicine immunopotentiator for treating the weak piglets, which comprises the following steps:
(1) mixing radix codonopsitis, fried bighead atractylodes rhizome, common yam rhizome, red paeony root, dried flowering peach, tuckahoe, rhizoma alismatis, raw astragalus root, szechuan lovage rhizome, tuber fleeceflower root, suberect spatholobus stem, divaricate saposhnikovia root and the like according to the parts by weight, and carrying out superfine grinding on the mixture to obtain mixed traditional Chinese medicine superfine powder;
(2) micronizing radix Ephedrae and herba Taraxaci separately;
(3) after superfine grinding, respectively soaking the mixed traditional Chinese medicine superfine powder, the ephedra root superfine powder and the dandelion superfine powder in 10 times of water for 1 hour;
(4) placing radix Ephedrae micropowder into Chinese medicinal extraction tank, boiling, maintaining slightly boiling state for 0.5 hr, placing mixed Chinese medicinal micropowder into Chinese medicinal extraction tank, boiling, maintaining slightly boiling state for 1.5 hr, placing herba Taraxaci micropowder into Chinese medicinal extraction tank, boiling, and maintaining slightly boiling state for 1 hr;
(5) respectively discharging the liquid, filtering, adding 4 times of water into the residue, continuing decocting according to the above steps for three times, mixing the three filtrates, mixing the filtrates of the mixed traditional Chinese medicine, radix Ephedrae and herba Taraxaci, concentrating at 50-60 deg.C until the concentration of crude drug is 0.1g/mL, bottling, and sterilizing to obtain the Chinese herbal medicine compound preparation.
Example 1
A compound Chinese herbal medicine immunopotentiator for treating weak pigs comprises the following components in parts by weight: 30 parts of codonopsis pilosula, 12 parts of fried bighead atractylodes rhizome, 30 parts of common yam rhizome, 12 parts of red paeony root, 30 parts of dried flowering peach, 30 parts of ephedra root, 15 parts of poria cocos, 15 parts of rhizoma alismatis, 20 parts of raw astragalus membranaceus, 12 parts of ligusticum wallichii, 15 parts of polygonum multiflorum, 30 parts of caulis spatholobi, 30 parts of dandelion and 10 parts of divaricate saposhnikovia root, and the compound preparation is prepared according to the preparation method.
Example 2
A compound Chinese herbal medicine immunopotentiator for treating weak pigs comprises the following components in parts by weight: 25 parts of codonopsis pilosula, 15 parts of fried bighead atractylodes rhizome, 35 parts of common yam rhizome, 13 parts of red paeony root, 37 parts of dried flowering peach, 40 parts of ephedra root, 25 parts of poria cocos, 18 parts of rhizoma alismatis, 25 parts of raw astragalus membranaceus, 20 parts of ligusticum wallichii, 20 parts of polygonum multiflorum, 40 parts of caulis spatholobi, 25 parts of dandelion and 5 parts of divaricate saposhnikovia root, and the compound preparation is prepared according to the preparation method.
Example 3
A compound Chinese herbal medicine immunopotentiator for treating weak pigs comprises the following components in parts by weight: 35 parts of codonopsis pilosula, 5 parts of fried bighead atractylodes rhizome, 40 parts of common yam rhizome, 15 parts of red paeony root, 25 parts of dried flowering peach, 20 parts of ephedra root, 30 parts of poria cocos, 25 parts of rhizoma alismatis, 30 parts of raw astragalus membranaceus, 18 parts of ligusticum wallichii, 25 parts of polygonum multiflorum, 20 parts of caulis spatholobi, 20 parts of dandelion and 15 parts of divaricate saposhnikovia root, and the compound preparation is prepared according to the preparation method.
200 weak pigs of 3 months old are selected and averagely divided into 4 groups, namely, an example 1 group, an example 2 group, an example 3 group and a control group, wherein each group comprises 50 pigs; the young weak piglets in the group of example 1, the group of example 2 and the group of example 3 are added with the compound Chinese herbal medicine preparation into drinking water according to the dose of 30g of crude drugs for each pig, and the drinking water is administrated once a day in the morning and once a day for 30 days continuously; the control group of young weak pigs was not treated at all; weighing after the administration, randomly taking 10 pigs in each group, collecting jugular venous blood by using a non-anticoagulation tube, centrifuging, taking serum, and detecting liver function (AST, ALT) and kidney function (CREA, BUN) according to the requirements of a full-automatic biochemical kit; detecting the swine fever antibody according to a detection method of a swine fever antibody ELISA kit; IgG level was detected according to the detection method of the IgG ELISA kit.
Before the test, the weak piglets show the symptoms of mental depression, anorexia, low lying and immobility, occasional walking, left shaking and right shaking, no response to the driving of breeders, lower weight than the piglets in the same period and the like, after the test, the weak piglets have the significant improvement of the spirit, strong driving response to the breeders, enhanced appetite, significantly increased feed intake, significantly increased exercise amount and exercise frequency, therefore, the compound Chinese herbal medicine preparation has better clinical curative effect on the weak piglets.
TABLE 1 influence (kg) of compound Chinese herbal medicine preparation on weight of physically weak piglets
Note: the same column of different letters indicates significant difference (P <0.05) and the same letters indicate insignificant difference (P > 0.05).
As can be seen from Table 1, before the test, the weight ratios of weak piglets of each group are uniform and the differences are not significant (P is more than 0.05); after the test, the weight of the weak piglets in the groups of example 1, example 2 and example 3 is higher than that of the control group, and the difference is significant (P <0.05), wherein the weight of the groups of example 1, example 2 and example 3 is the highest, but the difference is not significant (P >0.05) compared with the other groups 2, so that the compound Chinese herbal medicine preparation has the effect of increasing the weight of the weak piglets.
TABLE 2 influence of compound Chinese herbal medicine preparation on the level of swine fever antibody of physically weak piglets
Note: the same column of different letters indicates significant difference (P <0.05) and the same letters indicate insignificant difference (P > 0.05).
As can be seen from table 2, at the end of the experiment, the swine fever antibody levels of the weak piglets in the groups of example 1, example 2 and example 3 are significantly different (P <0.05) from those in the control group, wherein the swine fever antibody levels of the groups of example 1, example 2 and example 3 are the highest but are not significantly different (P >0.05) from those of the other groups 2, indicating that the compound herbal preparation has the effect of increasing the swine fever antibody level.
TABLE 3 Effect of Compound herbal formulations on piglet serum IgG levels
Note: the same column of different letters indicates significant difference (P <0.05) and the same letters indicate insignificant difference (P > 0.05).
As can be seen from table 3, at the end of the experiment, the serum IgG levels of the weak piglets in the groups of example 1, example 2 and example 3 were significantly different (P <0.05) from those in the control group, wherein the serum IgG antibody levels of the groups of example 1, example 2 and example 3 were the highest but the difference was not significant (P >0.05) from those of the other groups 2, indicating that the compound herbal preparation has the effect of increasing the serum IgG antibody level.
TABLE 4 influence of compound Chinese herbal medicine preparation on liver and kidney functions of piglets
Note: the same column of different letters indicates significant difference (P <0.05) and the same letters indicate insignificant difference (P > 0.05).
As can be seen from table 4, at the end of the test, the indexes of liver function (AST, ALT) and kidney function (CREA, BUN) of the physically weak piglets in example 1, example 2 and example 3 were lower than those of the control group, and the difference was significant (P <0.05), indicating that the compound Chinese herbal medicine preparation has the function of reducing the indexes of liver and kidney function of the physically weak piglets, and achieves the effect of protecting liver and kidney.
The foregoing shows and describes the general principles, essential features, and advantages of the invention. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed.
Claims (2)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910449133.XA CN110051770B (en) | 2019-05-28 | 2019-05-28 | Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910449133.XA CN110051770B (en) | 2019-05-28 | 2019-05-28 | Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN110051770A CN110051770A (en) | 2019-07-26 |
| CN110051770B true CN110051770B (en) | 2021-09-10 |
Family
ID=67324692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910449133.XA Active CN110051770B (en) | 2019-05-28 | 2019-05-28 | Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN110051770B (en) |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101653520A (en) * | 2008-08-22 | 2010-02-24 | 天津生机集团股份有限公司 | Chinese medicament composition for preventing and treating piglet intractable diarrhea and preparation method thereof |
| CN102772703A (en) * | 2012-08-02 | 2012-11-14 | 山西双鹰动物药业有限公司 | Drug for treating porcine reproductive and respiratory syndrome |
| CN103125776A (en) * | 2013-03-20 | 2013-06-05 | 江苏华锋国际农业博览园有限公司 | Preparation method of boar fatting forage |
| CN103251773A (en) * | 2013-05-21 | 2013-08-21 | 天津必佳药业集团有限公司 | Chinese medicine composite for treating pig high fever |
| CN103720988A (en) * | 2012-10-12 | 2014-04-16 | 天津君合心科技发展有限公司 | Chinese herbal medicine veterinary medicine compound for supplementing vacuity, tonifying qi and improving immunity |
| CN106819497A (en) * | 2017-04-17 | 2017-06-13 | 湖南赛福资源饲料科技有限公司 | A kind of feed for improving piglet anti diar rhea ability and preparation method thereof |
| CN106889341A (en) * | 2017-03-10 | 2017-06-27 | 天津市畜牧兽医研究所 | A kind of feed addictive for improving pigling immunity and preparation method and application |
| CN106913743A (en) * | 2015-12-24 | 2017-07-04 | 南京国雅信息科技有限公司 | A kind of herbal medicine of promotion growth of animal |
| CN106974094A (en) * | 2017-03-22 | 2017-07-25 | 长沙瑞多康生物科技有限公司 | A kind of feed of prevention swine gastric ulcer |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104147098A (en) * | 2014-08-25 | 2014-11-19 | 曹雨辰 | Traditional Chinese medicine veterinary drug ultra-micro powder for treating livestock and poultry immunosuppression disease and preparation method thereof |
| CN105192435A (en) * | 2015-11-02 | 2015-12-30 | 姚娟梅 | Traditional Chinese medicine feed additive for improving immunity of piglets, feed containing traditional Chinese medicine feed additive and preparation method of traditional Chinese medicine feed additive |
-
2019
- 2019-05-28 CN CN201910449133.XA patent/CN110051770B/en active Active
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101653520A (en) * | 2008-08-22 | 2010-02-24 | 天津生机集团股份有限公司 | Chinese medicament composition for preventing and treating piglet intractable diarrhea and preparation method thereof |
| CN102772703A (en) * | 2012-08-02 | 2012-11-14 | 山西双鹰动物药业有限公司 | Drug for treating porcine reproductive and respiratory syndrome |
| CN103720988A (en) * | 2012-10-12 | 2014-04-16 | 天津君合心科技发展有限公司 | Chinese herbal medicine veterinary medicine compound for supplementing vacuity, tonifying qi and improving immunity |
| CN103125776A (en) * | 2013-03-20 | 2013-06-05 | 江苏华锋国际农业博览园有限公司 | Preparation method of boar fatting forage |
| CN103251773A (en) * | 2013-05-21 | 2013-08-21 | 天津必佳药业集团有限公司 | Chinese medicine composite for treating pig high fever |
| CN106913743A (en) * | 2015-12-24 | 2017-07-04 | 南京国雅信息科技有限公司 | A kind of herbal medicine of promotion growth of animal |
| CN106889341A (en) * | 2017-03-10 | 2017-06-27 | 天津市畜牧兽医研究所 | A kind of feed addictive for improving pigling immunity and preparation method and application |
| CN106974094A (en) * | 2017-03-22 | 2017-07-25 | 长沙瑞多康生物科技有限公司 | A kind of feed of prevention swine gastric ulcer |
| CN106819497A (en) * | 2017-04-17 | 2017-06-13 | 湖南赛福资源饲料科技有限公司 | A kind of feed for improving piglet anti diar rhea ability and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 中兽药使仔猪增重;李宗燕;《畜牧兽医科技信息》;19990708(第13期);第4页 * |
| 参芪口服液质量控制及临床疗效观察;谭家风等;《上海医药》;19970315(第03期);第32-33页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN110051770A (en) | 2019-07-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN112972547B (en) | Traditional Chinese medicine composition for treating qi and blood deficiency syndrome and preparation method and application thereof | |
| CN102397372A (en) | Pharmaceutical composition, preparation and application of pharmaceutical composition in treating irritable bowel syndrome | |
| CN114558074A (en) | Traditional Chinese medicine composition for treating metabolic-related fatty liver disease and preparation method and application thereof | |
| CN101199672A (en) | Chinese medicine health care wine containing function of regulating human body immunity | |
| CN104288245A (en) | Pharmaceutical composition having functions of defying age and enhancing physique, preparation method and detection method thereof | |
| CN110051770B (en) | Compound Chinese herbal medicine immunopotentiator for treating weak piglets and preparation method thereof | |
| CN102225146A (en) | Formula and production technology of traditional Chinese medicine injection for controlling bird flu | |
| CN105327238A (en) | Traditional Chinese medicinal composition for tonifying spleen and stomach as well as preparation method and application of traditional Chinese medicinal composition | |
| CN111743994A (en) | Traditional Chinese medicine preparation for warming middle-jiao and invigorating spleen and preparation method thereof | |
| CN101485841B (en) | Health-care granule containing astragalus and coix seed | |
| CN109106887B (en) | Compound Chinese herbal medicine preparation for preventing white diarrhea of native chickens | |
| CN1289115C (en) | A kind of traditional Chinese medicine for improving immunity and preparation method thereof | |
| CN114366795B (en) | Traditional Chinese medicine composition and medicine for irritable bowel syndrome and preparation method and application thereof | |
| CN104306662A (en) | Traditional Chinese medicine composition for treating neurasthenia and preparation method thereof | |
| CN109876127B (en) | Blood-nourishing angelica sinensis capsule and preparation method thereof | |
| CN110960625A (en) | Chinese herbal medicine compound preparation for improving newcastle disease antibody level | |
| CN110025704B (en) | Compound Chinese herbal medicine preparation for treating piglet diarrhea and preparation method thereof | |
| CN115581740B (en) | Traditional Chinese medicine composition for preventing and treating porcine reproductive and respiratory syndrome and preparation method thereof | |
| CN110420258A (en) | A kind of cherokee rose root extract and its preparation method and application with establishing-Yang | |
| CN110396464A (en) | A kind of preparation method of milli wine | |
| CN103599317A (en) | Traditional Chinese medicinal composition for treating sleepiness and preparation method thereof | |
| CN101628012B (en) | Medicine composition with function of regulating immunity and preparation method thereof | |
| CN107007721B (en) | Traditional Chinese medicine compound preparation for treating anemia caused by qi deficiency of spleen and kidney and preparation method | |
| CN104548019A (en) | Use of traditional Chinese medicine preparation in preparation of medicine for treating diarrhea after chemotherapy | |
| CN109498794A (en) | A kind of Chinese medicine composition and preparation method thereof for improving immunity of livestock |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240531 Address after: Room 9001-9011, Shuangchuang Building (West Building), High tech Industrial Development Zone, Yu'an District, Lu'an City, Anhui Province, 237010 Patentee after: Lu'an Guonong Feed Co.,Ltd. Country or region after: China Address before: 237000 Hexi, Lu'an City, Anhui Province Patentee before: WEST ANHUI University Country or region before: China |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20240621 Address after: Zaolin Village, Shunhe Town, Yu'an District, Lu'an City, Anhui Province, 237146 Patentee after: Anhui Guonong livestock and poultry breeding technology Co.,Ltd. Country or region after: China Address before: Room 9001-9011, Shuangchuang Building (West Building), High tech Industrial Development Zone, Yu'an District, Lu'an City, Anhui Province, 237010 Patentee before: Lu'an Guonong Feed Co.,Ltd. Country or region before: China |
|
| TR01 | Transfer of patent right |