CN110037836B

CN110037836B - Skin-adhering bionic artificial breast and preparation method thereof

Info

Publication number: CN110037836B
Application number: CN201910325082.XA
Authority: CN
Inventors: 张妙玲; 范文静
Original assignee: Individual
Current assignee: Individual
Priority date: 2019-04-22
Filing date: 2019-04-22
Publication date: 2020-05-05
Anticipated expiration: 2039-04-22
Also published as: CN110037836A

Abstract

The invention belongs to the technical field of artificial breast manufacturing, and particularly relates to a skin-adhering bionic artificial breast and a preparation method thereof. The main structure of the bionic artificial breast comprises a cavity layer, a supporting layer and a bionic skin layer from inside to outside in sequence, the skin-adhering section of the main structure of the artificial breast further comprises a skin-adhering layer, the preparation process comprises the processes of molding, core injection, adhering the bionic skin layer, adhering the skin-adhering layer and the like, the preparation method is simple, the prepared bionic artificial breast has good skin-adhering property and good simulation property, and is suitable for being popularized and applied in a targeted manner.

Description

Skin-adhering bionic artificial breast and preparation method thereof

Technical Field

The invention belongs to the technical field of artificial breast manufacturing, and particularly relates to a skin-adhering bionic artificial breast and a preparation method thereof.

Background

Breast cancer is one of common malignant tumors of women and is high in the first ten causes of death, the incidence rate of breast cancer is second to cervical cancer in Chinese people, and the second place is the second place, although breast cancer is not the first ten causes of death of women in China, according to research, the average incidence age of breast cancer in Chinese people is eight to ten years less than that in European and American countries, and the incidence rate tends to be improved year by year.

Physical and psychological changes in physical impairment due to breast loss and psychological trauma have attracted attention from clinical medical workers and patients. Breast reconstruction after breast cancer operation can solve the problems to a certain extent, but patients are not suitable for breast reconstruction due to the visual reasons of disease conditions, age, economic conditions and the like.

The existing underwear specially used for the mastectomy is mainly characterized in that an interlayer is arranged on the underwear body corresponding to the cup parts at the resected side, the mastectomy person puts in two cushion bodies which are overlapped repeatedly, and the outer surfaces and the inner surfaces of the two cushion bodies have the same radian, so that the two cushion bodies are utilized to support the cup parts, and the situation that the cups at the side collapse due to no breast support is avoided. Therefore, a breast prosthesis is generally installed in a corresponding cup of the bra body to improve the breast shape and balance of the patient, and the breast prosthesis is made of various materials.

The shape and the weight of the current formed silica gel artificial breast are closest to the real skin material, most of the silica gel artificial breasts on the market are coated by a film, and are formed by silica gel without the film, but the problems of heavy weight, poor simulation and unreality exist no matter whether the silica gel artificial breast is coated by the film, and the weight bearing sense is strong when the artificial breast is worn; the artificial breast has the advantages that the artificial breast is pressed by pure sponge, has light weight and insufficient ductility, does not help the wound surface of a patient, can cause the weight imbalance of the left breast and the right breast of the human body, can cause the left and the right spines of the human body to be unbalanced for a long time, has very random shapes, and has insufficient appearance after being worn by the patient; no matter which kind of above artificial breast is not enough to stick skin to patient's skin, dressing and uncomfortable, no matter is patient's psychology, can not obtain fine solution in physiology and aesthetic measure chinese patent CN2017167795U discloses a structure of artificial breast bag, by the relative cavity bag body of sewing up the edge that first top layer is not inferior to second top layer cloth, this second top layer cloth comprises a table cloth and a table cloth, and is formed with a sack between upper surface cloth bottom edge and table cloth top edge, supplies the holding silica gel artificial breast. Can make the artificial breast and the human body generate structural support and elasticity to generate convection air, thereby effectively improving the air permeability. However, the artificial breast prepared by the utility model still needs to be improved in the aspects of fitting property, simulation property and the like.

Chinese patent application CN107854202A discloses a restore silica gel artificial milk next to shin, including the silica gel layer and with the skin layer is touched in the laminating of silica gel layer mutually, it has silica gel to fill in the silica gel layer, it has the thixotropy fluid to touch to fill in the skin layer, the silica gel artificial milk when using, touch the skin layer laminating human body, but the product that it made is the same with most of prior art in the aspect of pleasing to the eye and the fidelity, still can not satisfy the demand.

Therefore, although the artificial breast becomes an ideal choice for making up for the body defects and improving the external appearance after the operation of the patient, the common artificial breast products on the market have the problems of low simulation degree such as appearance, hand feeling, weight and the like, poor fitting property and the like.

Disclosure of Invention

In order to overcome the technical defects, the invention provides the skin-adhering bionic artificial breast which is simple in preparation method and good in simulation and adhesion of the prepared artificial breast.

In order to achieve the above purpose, the invention provides the following technical scheme:

a skin-adhering bionic artificial breast comprises a main body structure, wherein the main body structure sequentially comprises a cavity layer, a supporting layer and a bionic skin layer from inside to outside;

preferably, the biomimetic skin layer comprises a biomimetic nipple and a biomimetic skin;

preferably, the cavity layer is filled with liquid and air; preferably, the liquid is liquid silica gel or water;

preferably, the filling volume of the cavity layer is 85-90% of the total volume of the cavity (cavity filling saturation), wherein the liquid is 45-50% of the filling volume and the air is 50-55% of the filling volume.

Preferably, the support layer is made of medical silica gel;

preferably, the bionic skin layer is prepared from a high-molecular film;

preferably, the polymer film is a PE film (polyethylene film);

preferably, the polymer film is SBS (polystyrene-polydiene-polystyrene triblock copolymer) modified PE;

preferably, the raw materials for preparing the SBS modified PE comprise: PE, SBS, dibutyl phthalate and lubricant.

Preferably, the raw materials comprise, in percentage by weight of PE: 6-15% of SBS, 2-6% of dibutyl phthalate and 0.5-1% of lubricant.

Preferably, the preparation method of the SBS modified PE comprises the following steps: the raw materials are uniformly mixed, stirred at a high speed by a high-speed mixer, heated, plasticized and processed into a film.

Preferably, the skin-sticking layer is made of biological glue or medical silica gel.

Another objective of the present invention is to provide a method for preparing a skin-adhering biomimetic artificial breast, comprising the following steps:

(1) preparing an artificial breast structure by adopting a mould to form a supporting layer with a cavity inside;

(2) injecting liquid and air into the cavity to complete the core injection process;

(3) closing the supporting layer;

(4) a bionic skin layer is stuck and covered outside the supporting layer to form a main body structure of the artificial breast;

(5) covering a skin-sticking layer on the skin-sticking tangent plane of the main body structure of the artificial breast.

Preferably, in the step (1), the mold is made by 3D scanning of postoperative chest area data of a patient or female chest data required by conventional market, the mold is made of steel or aluminum, and the breast prosthesis structure is formed by demolding after reverse molding;

preferably, in step (2), the cavity has a degree of filling saturation of 85-90%;

preferably, in the step (3), the closing-in is performed by adopting a photo-curing technology or a silica gel glue brushing, solidifying and sealing;

preferably, in the step (4), the preparation method of the bionic skin layer comprises the following steps: the color-changing material is prepared by adopting a screen printing or ink-jet printing mode, the corresponding color of human skin is called, and the texture of the human skin is printed or printed on the high polymer film material.

Preferably, the bionic nipple and the bionic skin layer are integrally molded and printed;

preferably, after the bionic nipple and the bionic skin layer are printed and formed separately, the bionic nipple is pasted outside the bionic skin layer.

Preferably, in the step (5), the skin-adhering layer is brushed on the skin-adhering section in a brushing manner.

Compared with the prior art, the invention has the advantages that:

(1) the artificial breast prepared by the invention is more skin-friendly in hand feeling and more simulated in appearance; external force can be buffered, and the chest is effectively protected.

(2) The materials used in the invention are all nontoxic and harmless materials, and have good stability, good pasting effect and good skin-sticking performance.

(3) The artificial breast prepared by the invention can flexibly adjust the size of each product by controlling the amount of air or liquid which is careful according to the physical condition of a wearer, and can realize the purpose of personalized customization.

(4) The artificial breast can be customized in the chest area of a patient after a 3D scanning operation, and the effect that the height of a skin sticking surface is consistent with that of a wound surface is achieved.

Drawings

FIG. 1: a schematic diagram of a breast prosthesis structure;

FIG. 2: a schematic diagram of the manufacturing process of the artificial breast formed and printed by the bionic nipple and the bionic skin layer in an integrated manner;

FIG. 3: a schematic diagram of the manufacturing process of the artificial breast formed by separately printing the bionic nipple and the bionic skin layer;

the specific meanings of the symbols in the drawings are as follows: 1: liquid silica gel or water; 2: air; 3: a support layer; 4: a biomimetic skin layer; 5: simulating a nipple; 6: a skin-adhering layer;

the invention will now be further illustrated with reference to the accompanying drawings and examples:

Detailed Description

Example 1

The utility model provides a paste bionical artificial breast of skin, includes major structure, major structure includes cavity layer, supporting layer, bionical skin layer and bionical nipple from inside to outside in proper order, the major structure inboard of artificial breast still includes pastes the skin layer, and its preparation method is as follows:

(1) adopting female chest data required by the conventional market to manufacture a mold, adopting a steel mold to perform film pouring and demolding on medical silica gel to prepare an artificial breast structure, and forming a supporting layer with a cavity inside;

(2) injecting liquid silica gel and air into the cavity to ensure that the filling saturation of the cavity reaches 90 percent, wherein the percentage of the liquid silica gel to the air is 45 percent: 55%, completing the core injection process;

(3) closing the supporting layer by adopting a photocuring technology;

(4) pasting a bionic skin layer made of a PE film on the outer part of the supporting layer, wherein the bionic skin layer is prepared by adopting a screen printing mode, adjusting the corresponding color of the human skin, and printing the texture of the human skin on a high polymer film material; the nipple of the bionic skin layer and the skin are integrally formed (as shown in figure 2) to form a main body structure of the artificial breast;

(5) and brushing the biological glue on the skin-adhering section of the main body structure of the artificial breast in a glue brushing mode to form a skin-adhering layer.

Example 2

Preparing a polymer film:

PE, 8% SBS, 5% dibutyl phthalate and 0.7% lubricant are mixed uniformly, stirred at high speed by a high-speed mixer, heated and plasticized, and processed into a film to prepare the high polymer film.

(3) closing the supporting layer by adopting a photocuring technology;

(4) sticking a bionic skin layer made of a high polymer film on the outer part of the supporting layer, wherein the bionic skin layer is prepared by adopting a screen printing mode, adjusting the corresponding color of the human skin, and printing the texture of the human skin on the high polymer film material; the nipple of the bionic skin layer and the skin are integrally formed to form a main body structure of the artificial breast;

Example 3

Preparing a polymer film:

PE, 6% SBS, 2% dibutyl phthalate and 0.5% lubricant are mixed uniformly, stirred at high speed by a high-speed mixer, heated and plasticized, and processed into a film to prepare the high polymer film.

(1) preparing a mold by adopting 3D scanning of postoperative chest area data of a patient, and demoulding medical silica gel after the film is inverted by adopting an aluminum mold to prepare an artificial breast structure to form a supporting layer with a cavity inside;

(2) water and air were injected into the cavity to reach 85% cavity filling saturation, with a water to air percentage of 50%: 50%, completing the core injection process;

(3) closing the supporting layer in a sealing mode after the silica gel glue is brushed and solidified;

(4) sticking a bionic skin layer made of a high polymer film on the outer part of the supporting layer, wherein the bionic skin layer is prepared by adopting an ink-jet printing mode, the corresponding color of the human skin is called out, and the texture of the human skin is printed on the high polymer film material; after the bionic nipple and the bionic skin layer are printed and molded separately (as shown in figure 3), the bionic nipple is stuck outside the bionic skin layer to form a main body structure of the artificial breast;

(5) the high-viscosity medical silica gel is brushed on the skin-sticking tangent plane of the main body structure of the artificial breast in a glue brushing mode to form a skin-sticking layer.

Example 4

Preparing a polymer film:

PE, 15% SBS, 6% dibutyl phthalate and 1% lubricant are mixed uniformly, stirred at high speed by a high-speed mixer, heated and plasticized, and then processed into a film to prepare the high polymer film.

(2) injecting liquid silica gel and air into the cavity to ensure that the filling saturation of the cavity reaches 88%, wherein the percentage of the liquid silica gel to the air is 47%: 53%, completing the core injection process;

(3) closing the supporting layer by adopting a photocuring technology;

Comparative example 1 (different ratio of liquid silica gel to air compared with example 1)

(2) injecting liquid silica gel and air into the cavity to ensure that the filling saturation of the cavity reaches 85 percent, wherein the percentage of the liquid silica gel to the air is 65 percent: 35 percent, completing the core injection process;

(3) closing the supporting layer by adopting a photocuring technology;

(4) pasting a bionic skin layer made of a PE film on the outer part of the supporting layer, wherein the bionic skin layer is prepared by adopting a screen printing mode, adjusting the corresponding color of the human skin, and printing the texture of the human skin on a high polymer film material; the nipple of the bionic skin layer and the skin are integrally formed to form a main body structure of the artificial breast;

Comparative example 2 (different ratio of liquid silica gel to air compared with example 1)

(2) injecting liquid silica gel and air into the cavity to ensure that the filling saturation of the cavity reaches 85 percent, wherein the percentage of the liquid silica gel to the air is 25 percent: 75%, completing the core injection process;

(3) closing the supporting layer by adopting a photocuring technology;

Comparative example 3 (composition of polymer film is different from that of example 2)

Preparing a polymer film:

PE, 20% SBS, 5% dibutyl phthalate and 0.7% lubricant are mixed uniformly, stirred at high speed by a high-speed mixer, heated and plasticized, and processed into a film to prepare the high polymer film.

(3) closing the supporting layer by adopting a photocuring technology;

(4) sticking a bionic skin layer made of a high polymer film on the outer part of the supporting layer, wherein the bionic skin layer is prepared by adopting a screen printing mode, adjusting the corresponding color of the human skin, and printing the texture of the human skin on the high polymer film material; the nipple of the bionic skin layer and the skin are integrally formed (as shown in figure 2) to form a main body structure of the artificial breast;

COMPARATIVE EXAMPLE 4 (COMPARATIVE WITH THE PRIOR ART)

The silica gel artificial milk is prepared according to the method described in the specific example of the specification of the prior art CN 107854202A.

Examples of effects

Simulation test investigation: a random spot check of 50 persons was performed to fill out a simulation score for the products of examples 1-3 and comparative examples 1-3.

Skin-adhering property: and randomly dividing 60 persons into 6 groups, washing for 30min after wearing the shoes, and observing the falling condition.

Therefore, the bionic artificial breast prepared by the method has better simulation and skin-adhering property.

The above detailed description is specific to one possible embodiment of the present invention, and the embodiment is not intended to limit the scope of the present invention, and all equivalent implementations or modifications without departing from the scope of the present invention should be included in the technical scope of the present invention.

Claims

1. The preparation method of the skin-adhering bionic artificial breast is characterized in that the artificial breast comprises a main body structure, the main body structure sequentially comprises a cavity layer, a supporting layer and a bionic skin layer from inside to outside, the inner side of the main body structure of the artificial breast further comprises the skin-adhering layer, the skin-adhering layer is brushed on a skin-adhering section on the inner side of the main body structure in a glue brushing mode, and the bionic skin layer comprises a bionic nipple and a bionic skin; the supporting layer is made of medical silica gel; the bionic skin layer is prepared from a high-molecular film; the skin sticking layer is made of biological glue or medical silica gel;

the cavity layer is filled with liquid and air; the liquid is liquid silica gel; the filling volume of the cavity layer accounts for 85-90% of the total volume of the cavity, wherein the liquid accounts for 45-50% of the filling volume, and the air accounts for 50-55% of the filling volume;

the polymer film is an SBS modified PE film, and the SBS modified PE film is prepared from the following raw materials: PE, SBS, dibutyl phthalate and lubricant;

according to the weight percentage of PE, the raw materials comprise: 6-15% of SBS, 2-6% of dibutyl phthalate and 0.5-1% of lubricant;

the preparation method of the skin-adhering bionic artificial breast comprises the following steps:

(1) preparing a main body structure of the artificial breast by adopting a mould to form a supporting layer with a cavity inside;

(3) closing the supporting layer;

2. The method for preparing a skin-adhering biomimetic artificial breast according to claim 1,

in the step (1), the mold is made by 3D scanning of the chest area data after the operation of a patient or the female chest data required by the conventional market, the mold is a steel or aluminum mold, and the main structure of the artificial breast is formed by demolding after reverse molding;

in the step (3), the closing-in is carried out by adopting a photo-curing technology or a silica gel glue brushing solidification sealing;

in the step (4), the preparation method of the bionic skin layer comprises the following steps: the color-changing material is prepared by adopting a screen printing or ink-jet printing mode, the corresponding color of human skin is called out, and the human skin texture is printed on the high polymer film material;

in the step (5), the skin-sticking layer is brushed on the skin-sticking tangent plane in a glue brushing mode.

3. The method for preparing the skin-adhering bionic breast prosthesis according to claim 2, wherein the bionic skin layer comprises a bionic nipple and a bionic skin, and the bionic nipple and the bionic skin are integrally formed and printed.

4. The method for preparing the skin-attached bionic breast prosthesis according to claim 2, wherein the bionic skin layer comprises a bionic nipple and a bionic skin, and the bionic nipple is pasted outside the bionic skin after being printed and molded separately from the bionic skin.